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JUN-ICHI ABE

TitleProfessor
InstitutionMD Anderson
DepartmentCardiology
Address2121 Holcombe Blvd
Houston TX 77030-4244
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Millar MW, Najar RA, Slavin SA, Shadab M, Tahir I, Mahamed Z, Lin X, Abe JI, Wright TW, Dean DA, Fazal F, Rahman A, Millar MW, Najar RA, Slavin SA, Shadab M, Tahir I, Mahamed Z, Lin X, Abe JI, Wright TW, Dean DA, Fazal F, Rahman A. MTOR maintains endothelial cell integrity to limit lung vascular injury. J Biol Chem. 2024 Nov 06; 300(12):107952. PMID: 39510184.
      Citations:    Fields:    
    2. Abu Rmilah A, Adham A, Ikram-Ul H, Alzu'bi H, Nandan A, Jouni H, Hirashi S, Owen D, Deswal A, Lin SH, Abe JI, Chao TC, Browne J, Leiner T, Laack N, Herrmann J. Novel risk score for predicting acute cardiovascular and cerebrovascular events after chest radiotherapy in patients with breast or lung cancer. Eur J Prev Cardiol. 2024 Oct 25. PMID: 39453776.
      Citations:    Fields:    
    3. Abe JI, Allen BG, Beyer AM, Lewandowski D, Mapuskar KA, Subramanian V, Tamplin MR, Grumbach IM, Allen BG, Beyer AM, Lewandowski D, Mapuskar KA, Subramanian V, Tamplin MR, Grumbach IM. Radiation-Induced Macrovessel/Microvessel Disease. Arterioscler Thromb Vasc Biol. 2024 Dec; 44(12):2407-2415. PMID: 39445428.
      Citations:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
    4. Nead KT, Kim T, Joo L, McDowell T, Wong J, Chan IC, Brock E, Zhao J, Xu T, Tang C, Lee CL, Abe JI, Bolton KL, Liao Z, Scheet P, Lin SH, Nead KT, Kim T, Joo L, McDowell TL, Wong JW, Chan ICC, Brock E, Zhao J, Xu T, Tang C, Lee CL, Abe JI, Bolton KL, Liao Z, Scheet PA, Lin SH. Impact of cancer therapy on clonal hematopoiesis mutations and subsequent clinical outcomes. Blood Adv. 2024 10 08; 8(19):5215-5224. PMID: 38830141; PMCID: PMC11530395.
      Citations: 2     Fields:    Translation:Humans
    5. Koutroumpakis E, Naser MA, Mohamed ASR, Eraj SA, Jarre A, Shiao JC, Kamal M, Perni S, Phan JP, Morrison WH, Frank SJ, Gunn GB, Garden AS, Deswal A, Abe JI, Rosenthal DI, Mouhayar E, Fuller CD. Detection of Alteration in Carotid Artery Volumetry Using Standard-of-care Computed Tomography Surveillance Scans Following Unilateral Radiation Therapy for Early-stage Tonsillar Squamous Cell Carcinoma Survivors: A Cross-Sectional Internally-Matched Carotid Isodose Analysis. medRxiv. 2024 May 16. PMID: 38798400; PMCID: PMC11118557.
      Citations:    
    6. Chau KM, Dominic A, Davis EL, Kotla S, Berrios ET, Fahim A, Arunesh A, Li S, Zhao D, Chen K, Davis AR, Nguyen MTH, Wang Y, Evans SE, Wang G, Cooke JP, Abe JI, Huston DP, Le NT. TNIK regulation of interferon signaling and endothelial cell response to virus infection. Front Cardiovasc Med. 2023; 10:1213428. PMID: 38264262; PMCID: PMC10803426.
      Citations:    
    7. Reyes-Gibby CC, Qdaisat A, Ferrarotto R, Fadol A, Bischof JJ, Coyne CJ, Lipe DN, Hanna EY, Shete S, Abe JI, Yeung SJ. Cardiovascular events after cancer immunotherapy as oncologic emergencies: Analyses of 610 head and neck cancer patients treated with immune checkpoint inhibitors. Head Neck. 2024 03; 46(3):627-635. PMID: 38151809; PMCID: PMC10922978.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    8. Dhar SS, Brown C, Rizvi A, Reed L, Kotla S, Zod C, Abraham J, Abe JI, Rajaram V, Chen K, Lee M. Heterozygous Kmt2d loss diminishes enhancers to render medulloblastoma cells vulnerable to combinatory inhibition of lysine demethylation and oxidative phosphorylation. bioRxiv. 2023 Nov 09. PMID: 37961118; PMCID: PMC10634931.
      Citations:    
    9. Jain A, Casanova D, Padilla AV, Paniagua Bojorges A, Kotla S, Ko KA, Samanthapudi VSK, Chau K, Nguyen MTH, Wen J, Hernandez Gonzalez SL, Rodgers SP, Olmsted-Davis EA, Hamilton DJ, Reyes-Gibby C, Yeung SJ, Cooke JP, Herrmann J, Chini EN, Xu X, Yusuf SW, Yoshimoto M, Lorenzi PL, Hobbs B, Krishnan S, Koutroumpakis E, Palaskas NL, Wang G, Deswal A, Lin SH, Abe JI, Le NT. Premature senescence and cardiovascular disease following cancer treatments: mechanistic insights. Front Cardiovasc Med. 2023; 10:1212174. PMID: 37781317; PMCID: PMC10540075.
      Citations:    
    10. Savage H, Pareek S, Lee J, Ballar? R, Conterno Minussi D, Hayek K, Sadullozoda M, Lochmann BS, McQuade JL, LaVoy EC, Marmonti E, Patel H, Wang G, Imanishi M, Kotla S, Abe JI, Schadler K. Aerobic Exercise Alters the Melanoma Microenvironment and Modulates ERK5 S496 Phosphorylation. Cancer Immunol Res. 2023 09 01; 11(9):1168-1183. PMID: 37307577; PMCID: PMC10527747.
      Citations: 2     Fields:    Translation:AnimalsCells
    11. Nguyen MTH, Imanishi M, Li S, Chau K, Banerjee P, Velatooru LR, Ko KA, Samanthapudi VSK, Gi YJ, Lee LL, Abe RJ, McBeath E, Deswal A, Lin SH, Palaskas NL, Dantzer R, Fujiwara K, Borchrdt MK, Turcios EB, Olmsted-Davis EA, Kotla S, Cooke JP, Wang G, Abe JI, Le NT. Endothelial activation and fibrotic changes are impeded by laminar flow-induced CHK1-SENP2 activity through mechanisms distinct from endothelial-to-mesenchymal cell transition. Front Cardiovasc Med. 2023; 10:1187490. PMID: 37711550; PMCID: PMC10499395.
      Citations:    
    12. Ewer MS, Yusuf SW, Asmis R, Abe JI. Editorial: Case reports in cardio-oncology: 2022. Front Cardiovasc Med. 2023; 10:1235015. PMID: 37522080; PMCID: PMC10374430.
      Citations:    
    13. Abe JI, Imanishi M, Li S, Zhang A, Ko KA, Samanthapudi VSK, Lee LL, Bojorges AP, Gi YJ, Hobbs BP, Deswal A, Herrmann J, Lin SH, Chini EN, Shen YH, Schadler KL, Nguyen TH, Gupte AA, Reyes-Gibby C, Yeung SJ, Abe RJ, Olmsted-Davis EA, Krishnan S, Dantzer R, Palaskas NL, Cooke JP, Pownall HJ, Yoshimoto M, Fujiwara K, Hamilton DJ, Burks JK, Wang G, Le NT, Kotla S. An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis. Circ Res. 2023 06 23; 133(1):25-44. PMID: 37264926; PMCID: PMC10357365.
      Citations: 3     Fields:    Translation:Animals
    14. Banerjee P, Rosales JE, Chau K, Nguyen MTH, Kotla S, Lin SH, Deswal A, Dantzer R, Olmsted-Davis EA, Nguyen H, Wang G, Cooke JP, Abe JI, Le NT. Possible molecular mechanisms underlying the development of atherosclerosis in cancer survivors. Front Cardiovasc Med. 2023; 10:1186679. PMID: 37332576; PMCID: PMC10272458.
      Citations: 3     
    15. Gurshaney S, Morales-Alvarez A, Ezhakunnel K, Manalo A, Huynh TH, Abe JI, Le NT, Weiskopf D, Sette A, Lupu DS, Gardell SJ, Nguyen H. Metabolic dysregulation impairs lymphocyte function during severe SARS-CoV-2 infection. Commun Biol. 2023 04 07; 6(1):374. PMID: 37029220; PMCID: PMC10080180.
      Citations:    Translation:HumansCells
    16. Li S, Zhang P, Chen W, Ye L, Brannan KW, Le NT, Abe JI, Cooke JP, Wang G. A relay velocity model infers cell-dependent RNA velocity. Nat Biotechnol. 2024 Jan; 42(1):99-108. PMID: 37012448; PMCID: PMC10545816.
      Citations: 1     Fields:    
    17. Imanishi M, Cheng H, Kotla S, Deswal A, Le NT, Chini E, Ko KA, Samanthapudi VSK, Lee LL, Herrmann J, Xu X, Reyes-Gibby C, Yeung SJ, Schadler KL, Yusuf SW, Liao Z, Nurieva R, Amir ED, Burks JK, Palaskas NL, Cooke JP, Lin SH, Kobayashi M, Yoshimoto M, Abe JI. Radiation therapy induces immunosenescence mediated by p90RSK. Front Cardiovasc Med. 2022; 9:988713. PMID: 36426217; PMCID: PMC9680092.
      Citations: 3     
    18. Wang Y, Abe JI, Chau KM, Wang Y, Vu HT, Reddy Velatooru L, Gulraiz F, Imanishi M, Samanthapudi VSK, Nguyen MTH, Ko KA, Lee LL, Thomas TN, Olmsted-Davis EA, Kotla S, Fujiwara K, Cooke JP, Zhao D, Evans SE, Le NT. MAGI1 inhibits interferon signaling to promote influenza A infection. Front Cardiovasc Med. 2022; 9:791143. PMID: 36082118; PMCID: PMC9445416.
      Citations:    
    19. Koutroumpakis E, Agrawal N, Palaskas NL, Abe JI, Iliescu C, Yusuf SW, Deswal A. Myocardial Dysfunction in Patients with Cancer. Heart Fail Clin. 2022 Jul; 18(3):361-374. PMID: 35718412.
      Citations:    Fields:    Translation:Humans
    20. Ju Z, Thomas TN, Chiu YJ, Yamanouchi S, Yoshida Y, Abe JI, Takahashi A, Wang J, Fujiwara K, Hada M. Adaptation and Changes in Actin Dynamics and Cell Motility as Early Responses of Cultured Mammalian Cells to Altered Gravitational Vector. Int J Mol Sci. 2022 May 30; 23(11). PMID: 35682810; PMCID: PMC9181735.
      Citations:    Fields:    Translation:AnimalsCells
    21. Banerjee P, Olmsted-Davis EA, Deswal A, Nguyen MT, Koutroumpakis E, Palaskas NL, Lin SH, Kotla S, Reyes-Gibby C, Yeung SJ, Yusuf SW, Yoshimoto M, Kobayashi M, Yu B, Schadler K, Herrmann J, Cooke JP, Jain A, Chini E, Le NT, Abe JI. Cancer treatment-induced NAD+ depletion in premature senescence and late cardiovascular complications. J Cardiovasc Aging. 2022; 2. PMID: 35801078; PMCID: PMC9258520.
      Citations:    
    22. Shobayo F, Bajwa M, Koutroumpakis E, Hassan SA, Palaskas NL, Iliescu C, Abe JI, Mouhayar E, Karimzad K, Thompson KA, Deswal A, Yusuf SW. Acute coronary syndrome in patients with cancer. Expert Rev Cardiovasc Ther. 2022 Apr; 20(4):275-290. PMID: 35412407.
      Citations:    Fields:    Translation:Humans
    23. Abe RJ, Abe JI, Nguyen MTH, Olmsted-Davis EA, Mamun A, Banerjee P, Cooke JP, Fang L, Pownall H, Le NT. Free Cholesterol Bioavailability and Atherosclerosis. Curr Atheroscler Rep. 2022 05; 24(5):323-336. PMID: 35332444; PMCID: PMC9050774.
      Citations:    Fields:    Translation:HumansAnimals
    24. Le NT, Olmsted-Davis EA, Abe JI. Paradoxical effects of osteoprotegerin on vascular function: inhibiting inflammation while promoting oxidative stress? Clin Sci (Lond). 2022 03 18; 136(5):379-382. PMID: 35274135; PMCID: PMC8919090.
      Citations:    Fields:    Translation:HumansCells
    25. Wang X, Palaskas NL, Hobbs BP, Abe JI, Nead KT, Yusuf SW, Hermann J, Deswal A, Lin SH. The Impact of Radiation Dose to Heart Substructures on Major Coronary Events and Patient Survival after Chemoradiation Therapy for Esophageal Cancer. Cancers (Basel). 2022 Mar 03; 14(5). PMID: 35267613; PMCID: PMC8909404.
      Citations: 1     
    26. Koutroumpakis E, Deswal A, Yusuf SW, Abe JI, Nead KT, Potter AS, Liao Z, Lin SH, Palaskas NL. Radiation-Induced Cardiovascular Disease: Mechanisms, Prevention, and Treatment. Curr Oncol Rep. 2022 05; 24(5):543-553. PMID: 35192118.
      Citations:    Fields:    Translation:HumansPHPublic Health
    27. Banerjee P, Kotla S, Reddy Velatooru L, Abe RJ, Davis EA, Cooke JP, Schadler K, Deswal A, Herrmann J, Lin SH, Abe JI, Le NT. Senescence-Associated Secretory Phenotype as a Hinge Between Cardiovascular Diseases and Cancer. Front Cardiovasc Med. 2021; 8:763930. PMID: 34746270; PMCID: PMC8563837.
      Citations: 4     
    28. Kotla S, Zhang A, Imanishi M, Ko KA, Lin SH, Gi YJ, Moczygemba M, Isgandarova S, Schadler KL, Chung C, Milgrom SA, Banchs J, Yusuf SW, Amaya DN, Guo H, Thomas TN, Shen YH, Deswal A, Herrmann J, Kleinerman ES, Entman ML, Cooke JP, Schifitto G, Maggirwar SB, McBeath E, Gupte AA, Krishnan S, Patel ZS, Yoon Y, Burks JK, Fujiwara K, Brookes PS, Le NT, Hamilton DJ, Abe JI. Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation. Redox Biol. 2021 11; 47:102132. PMID: 34619528; PMCID: PMC8502954.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    29. Shen YH, Abe JI. Nrg1? as a Proangiogenesis Therapy: How Is Nrg1? Therapy Unique From Other Angiogenesis Therapies? Arterioscler Thromb Vasc Biol. 2021 08; 41(8):2315-2317. PMID: 34162231; PMCID: PMC8631478.
      Citations: 1     Fields:    
    30. Yano K, Takahashi RU, Shiotani B, Abe J, Shidooka T, Sudo Y, Yamamoto Y, Kan S, Sakagami H, Tahara H. PRPF19 regulates p53-dependent cellular senescence by modulating alternative splicing of MDM4 mRNA. J Biol Chem. 2021 07; 297(1):100882. PMID: 34144037; PMCID: PMC8274299.
      Citations: 2     Fields:    Translation:HumansCells
    31. Abe RJ, Savage H, Imanishi M, Banerjee P, Kotla S, Paez-Mayorga J, Taunton J, Fujiwara K, Won JH, Yusuf SW, Palaskas NL, Banchs J, Lin SH, Schadler KL, Abe JI, Le NT. Corrigendum: p90RSK-MAGI1 Module Controls Endothelial Permeability by Post-translational Modifications of MAGI1 and Hippo Pathway. Front Cardiovasc Med. 2021; 8:663486. PMID: 33681312; PMCID: PMC7934140.
      Citations:    
    32. Cornwell A, Palli R, Singh MV, Benoodt L, Tyrell A, Abe JI, Schifitto G, Maggirwar SB, Thakar J. Molecular characterization of atherosclerosis in HIV positive persons. Sci Rep. 2021 02 05; 11(1):3232. PMID: 33547350; PMCID: PMC7865026.
      Citations: 1     Fields:    Translation:HumansCells
    33. Abe JI, Yusuf SW, Deswal A, Herrmann J. Cardio-Oncology: Learning From the Old, Applying to the New. Front Cardiovasc Med. 2020; 7:601893. PMID: 33324688; PMCID: PMC7723824.
      Citations: 3     
    34. Abe RJ, Savage H, Imanishi M, Banerjee P, Kotla S, Paez-Mayorga J, Taunton J, Fujiwara K, Won JH, Yusuf SW, Palaskas NL, Banchs J, Lin SH, Schadler KL, Abe JI, Le NT. p90RSK-MAGI1 Module Controls Endothelial Permeability by Post-translational Modifications of MAGI1 and Hippo Pathway. Front Cardiovasc Med. 2020; 7:542485. PMID: 33304925; PMCID: PMC7693647.
      Citations: 3     
    35. Moudgil R, Samra G, Ko KA, Vu HT, Thomas TN, Luo W, Chang J, Reddy AK, Fujiwara K, Abe JI. Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway. Front Cardiovasc Med. 2020; 7:594123. PMID: 33330654; PMCID: PMC7709875.
      Citations: 2     
    36. Dominic A, Hamilton D, Abe JI. Mitochondria and chronic effects of cancer therapeutics: The clinical implications. J Thromb Thrombolysis. 2021 May; 51(4):884-889. PMID: 33079380; PMCID: PMC8055726.
      Citations: 3     Fields:    Translation:HumansCells
    37. Koutroumpakis E, Palaskas NL, Lin SH, Abe JI, Liao Z, Banchs J, Deswal A, Yusuf SW. Modern Radiotherapy and Risk of Cardiotoxicity. Chemotherapy. 2020; 65(3-4):65-76. PMID: 33049738.
      Citations: 4     Fields:    Translation:Humans
    38. Wang X, Palaskas NL, Yusuf SW, Abe JI, Lopez-Mattei J, Banchs J, Gladish GW, Lee P, Liao Z, Deswal A, Lin SH. Incidence and Onset of Severe Cardiac Events After Radiotherapy for Esophageal Cancer. J Thorac Oncol. 2020 10; 15(10):1682-1690. PMID: 32599073; PMCID: PMC9398884.
      Citations: 8     Fields:    Translation:Humans
    39. Kinoshita D, Shishido T, Takahashi T, Yokoyama M, Sugai T, Watanabe K, Tamura H, Nishiyama S, Takahashi H, Arimoto T, Miyamoto T, Watanabe T, Kishida S, Kadomatsu K, Abe JI, Takeishi Y, Konta T, Kubota I, Watanabe M. Growth Factor Midkine Aggravates Pulmonary Arterial Hypertension via Surface Nucleolin. Sci Rep. 2020 06 25; 10(1):10345. PMID: 32587339; PMCID: PMC7316741.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    40. Dominic A, Banerjee P, Hamilton DJ, Le NT, Abe JI. Time-dependent replicative senescence vs. disturbed flow-induced pre-mature aging in atherosclerosis. Redox Biol. 2020 10; 37:101614. PMID: 32863187; PMCID: PMC7767754.
      Citations: 12     Fields:    Translation:HumansCells
    41. McBeath E, Parker-Thornburg J, Fujii Y, Aryal N, Smith C, Hofmann MC, Abe JI, Fujiwara K. Rapid Evaluation of CRISPR Guides and Donors for Engineering Mice. Genes (Basel). 2020 Jun 08; 11(6). PMID: 32521708; PMCID: PMC7349695.
      Citations: 1     Fields:    Translation:Animals
    42. Quintana RA, Bui LP, Moudgil R, Palaskas N, Hassan S, Abe JI, Mouhayar E, Yusuf SW, Hernandez A, Banchs J. Speckle-Tracking Echocardiography in Cardio-Oncology and Beyond. Tex Heart Inst J. 2020 04 01; 47(2):96-107. PMID: 32603473; PMCID: PMC7328079.
      Citations: 2     Fields:    Translation:Humans
    43. Luo W, Wang Y, Zhang L, Ren P, Zhang C, Li Y, Azares AR, Zhang M, Guo J, Ghaghada KB, Starosolski ZA, Rajapakshe K, Coarfa C, Li Y, Chen R, Fujiwara K, Abe JI, Coselli JS, Milewicz DM, LeMaire SA, Shen YH. Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture. Circulation. 2020 01 07; 141(1):42-66. PMID: 31887080; PMCID: PMC6939474.
      Citations: 34     Fields:    Translation:AnimalsCells
    44. Mahadeo KM, Bajwa R, Abdel-Azim H, Lehmann LE, Duncan C, Zantek N, Vittorio J, Angelo J, McArthur J, Schadler K, Chan S, Tewari P, Khazal S, Auletta JJ, Choi SW, Shoberu B, Kalwak K, Harden A, Kebriaei P, Abe JI, Li S, Moffet JR, Abraham S, Tambaro FP, Kleinschmidt K, Richardson PG, Corbacioglu S, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network and the Pediatric Diseases Wor. Diagnosis, grading, and treatment recommendations for children, adolescents, and young adults with sinusoidal obstructive syndrome: an international expert position statement. Lancet Haematol. 2020 Jan; 7(1):e61-e72. PMID: 31818728.
      Citations: 9     Fields:    Translation:Humans
    45. Milgrom SA, Varghese B, Gladish GW, Choi AD, Dong W, Patel ZS, Chung CC, Rao A, Pinnix CC, Gunther JR, Dabaja BS, Lin SH, Hoffman KE, Huff JL, Slagowski J, Abe JI, Iliescu CA, Banchs J, Yusuf SW, Lopez-Mattei JC. Coronary Artery Dose-Volume Parameters Predict Risk of Calcification After Radiation Therapy. J Cardiovasc Imaging. 2019 Oct; 27(4):268-279. PMID: 31614398; PMCID: PMC6795565.
      Citations: 12     
    46. Kotla S, Le NT, Vu HT, Ko KA, Gi YJ, Thomas TN, Giancursio C, Lusis AJ, Cooke JP, Fujiwara K, Abe JI. Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase. Metabolism. 2019 11; 100:153962. PMID: 31476350; PMCID: PMC7059097.
      Citations: 8     Fields:    Translation:HumansCells
    47. Shen YH, Abe JI. Enigma of Inflammasome Activation by Kinases. Arterioscler Thromb Vasc Biol. 2019 08; 39(8):1501-1503. PMID: 31339780; PMCID: PMC6995302.
      Citations:    Fields:    Translation:HumansCells
    48. Lin L, Shi C, Sun Z, Le NT, Abe JI, Hu K. The Ser/Thr kinase p90RSK promotes kidney fibrosis by modulating fibroblast-epithelial crosstalk. J Biol Chem. 2019 06 21; 294(25):9901-9910. PMID: 31076505; PMCID: PMC6597816.
      Citations: 5     Fields:    Translation:AnimalsCells
    49. Kotla S, Vu HT, Ko KA, Wang Y, Imanishi M, Heo KS, Fujii Y, Thomas TN, Gi YJ, Mazhar H, Paez-Mayorga J, Shin JH, Tao Y, Giancursio CJ, Medina JL, Taunton J, Lusis AJ, Cooke JP, Fujiwara K, Le NT, Abe JI. Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2-interacting protein. JCI Insight. 2019 05 02; 4(9). PMID: 31045573; PMCID: PMC6538340.
      Citations: 11     Fields:    Translation:AnimalsCells
    50. Takahashi T, Shishido T, Kinoshita D, Watanabe K, Toshima T, Sugai T, Narumi T, Otaki Y, Tamura H, Nishiyama S, Arimoto T, Takahashi H, Miyamoto T, Watanabe T, Woo CH, Abe JI, Takeishi Y, Kubota I, Watanabe M. Cardiac Nuclear High-Mobility Group?Box?1 Ameliorates Pathological Cardiac Hypertrophy by Inhibiting DNA?Damage?Response. JACC Basic Transl Sci. 2019 Apr; 4(2):234-247. PMID: 31061925; PMCID: PMC6488753.
      Citations: 10     
    51. Abe JI, Sood AK, Martin JF. Editorial: Cardio-Oncology: From Bench to Bedside. Front Cardiovasc Med. 2019; 6:37. PMID: 31024931; PMCID: PMC6467926.
      Citations:    
    52. Abe JI, Ko KA, Kotla S, Wang Y, Paez-Mayorga J, Shin IJ, Imanishi M, Vu HT, Tao Y, Leiva-Juarez MM, Thomas TN, Medina JL, Won JH, Fujii Y, Giancursio CJ, McBeath E, Shin JH, Guzman L, Abe RJ, Taunton J, Mochizuki N, Faubion W, Cooke JP, Fujiwara K, Evans SE, Le NT. MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis. JCI Insight. 2019 04 04; 4(7). PMID: 30944250; PMCID: PMC6483653.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    53. Singh MV, Kotla S, Le NT, Ae Ko K, Heo KS, Wang Y, Fujii Y, Thi Vu H, McBeath E, Thomas TN, Jin Gi Y, Tao Y, Medina JL, Taunton J, Carson N, Dogra V, Doyley MM, Tyrell A, Lu W, Qiu X, Stirpe NE, Gates KJ, Hurley C, Fujiwara K, Maggirwar SB, Schifitto G, Abe JI. Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV-Positive Individuals. Circulation. 2019 02 26; 139(9):1199-1216. PMID: 30586719; PMCID: PMC6957233.
      Citations: 14     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    54. Le NT, Abe JI. MicroRNA 199a and the eNOS (Endothelial NO Synthase)/NO Pathway. Arterioscler Thromb Vasc Biol. 2018 10; 38(10):2278-2280. PMID: 30354226; PMCID: PMC6957222.
      Citations: 1     Fields:    
    55. Venkatesulu BP, Mahadevan LS, Aliru ML, Yang X, Bodd MH, Singh PK, Yusuf SW, Abe JI, Krishnan S. Radiation-Induced Endothelial Vascular?Injury: A Review of Possible Mechanisms. JACC Basic Transl Sci. 2018 Aug; 3(4):563-572. PMID: 30175280; PMCID: PMC6115704.
      Citations: 48     
    56. Ko KA, Wang Y, Kotla S, Fujii Y, Vu HT, Venkatesulu BP, Thomas TN, Medina JL, Gi YJ, Hada M, Grande-Allen J, Patel ZS, Milgrom SA, Krishnan S, Fujiwara K, Abe JI. Developing a Reliable Mouse Model for Cancer Therapy-Induced Cardiovascular Toxicity in Cancer Patients and Survivors. Front Cardiovasc Med. 2018; 5:26. PMID: 29675417; PMCID: PMC5896304.
      Citations: 3     
    57. Vu HT, Kotla S, Ko KA, Fujii Y, Tao Y, Medina J, Thomas T, Hada M, Sood AK, Singh PK, Milgrom SA, Krishnan S, Fujiwara K, Le NT, Abe JI. Ionizing Radiation Induces Endothelial Inflammation and Apoptosis via p90RSK-Mediated ERK5 S496 Phosphorylation. Front Cardiovasc Med. 2018; 5:23. PMID: 29594152; PMCID: PMC5861757.
      Citations: 5     
    58. Le NT, Abe JI. Regulation of Kir2.1 Function Under Shear Stress and Cholesterol Loading. J Am Heart Assoc. 2018 03 03; 7(5). PMID: 29502108; PMCID: PMC5866345.
      Citations: 1     Fields:    Translation:Animals
    59. Sylvester CB, Abe JI, Patel ZS, Grande-Allen KJ. Radiation-Induced Cardiovascular Disease: Mechanisms and Importance of Linear Energy Transfer. Front Cardiovasc Med. 2018; 5:5. PMID: 29445728; PMCID: PMC5797745.
      Citations: 22     
    60. Lin SC, Lee YC, Yu G, Cheng CJ, Zhou X, Chu K, Murshed M, Le NT, Baseler L, Abe JI, Fujiwara K, deCrombrugghe B, Logothetis CJ, Gallick GE, Yu-Lee LY, Maity SN, Lin SH. Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer. Dev Cell. 2017 06 05; 41(5):467-480.e3. PMID: 28586644; PMCID: PMC5512590.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    61. Ko KA, Fujiwara K, Krishnan S, Abe JI. En Face Preparation of Mouse Blood Vessels. J Vis Exp. 2017 05 19; (123). PMID: 28570508; PMCID: PMC5608002.
      Citations: 9     Fields:    Translation:Animals
    62. Mao Y, Luo W, Zhang L, Wu W, Yuan L, Xu H, Song J, Fujiwara K, Abe JI, LeMaire SA, Wang XL, Shen YH. STING-IRF3 Triggers Endothelial Inflammation in Response to Free Fatty Acid-Induced Mitochondrial Damage in Diet-Induced Obesity. Arterioscler Thromb Vasc Biol. 2017 05; 37(5):920-929. PMID: 28302626; PMCID: PMC5408305.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    63. Le NT, Martin JF, Fujiwara K, Abe JI. Sub-cellular localization specific SUMOylation in the heart. Biochim Biophys Acta Mol Basis Dis. 2017 08; 1863(8):2041-2055. PMID: 28130202; PMCID: PMC5716640.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    64. Abe JI, Sandhu UG, Hoang NM, Thangam M, Quintana-Quezada RA, Fujiwara K, Le NT. Coordination of Cellular Localization-Dependent Effects of Sumoylation in Regulating Cardiovascular and Neurological Diseases. Adv Exp Med Biol. 2017; 963:337-358. PMID: 28197922; PMCID: PMC5716632.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    65. Le NT, Sandhu UG, Quintana-Quezada RA, Hoang NM, Fujiwara K, Abe JI. Flow signaling and atherosclerosis. Cell Mol Life Sci. 2017 05; 74(10):1835-1858. PMID: 28039525; PMCID: PMC5391278.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    66. Abe J, Martin JF, Yeh ET. The Future of Onco-Cardiology: We Are Not Just "Side Effect Hunters". Circ Res. 2016 09 30; 119(8):896-9. PMID: 27688305; PMCID: PMC5147506.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    67. Abe J. Multiple Functions of Protein Inhibitor of Activated STAT1 in Regulating Endothelial Cell Proliferation and Inflammation. Arterioscler Thromb Vasc Biol. 2016 09; 36(9):1717-9. PMID: 27559144; PMCID: PMC5147510.
      Citations: 1     Fields:    Translation:Humans
    68. Abe J, Morrell C. Pyroptosis as a Regulated Form of Necrosis: PI+/Annexin V-/High Caspase 1/Low Caspase 9 Activity in Cells = Pyroptosis? Circ Res. 2016 05 13; 118(10):1457-60. PMID: 27174943; PMCID: PMC5137941.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    69. Heo KS, Berk BC, Abe J. Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events. Antioxid Redox Signal. 2016 09 01; 25(7):435-50. PMID: 26714841; PMCID: PMC5076483.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    70. Chang E, Abe JI. Kinase-SUMO networks in diabetes-mediated cardiovascular disease. Metabolism. 2016 May; 65(5):623-633. PMID: 27085771; PMCID: PMC5226250.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    71. Batchu SN, Xia J, Ko KA, Doyley MM, Abe J, Morrell CN, Korshunov VA. Axl modulates immune activation of smooth muscle cells in vein graft remodeling. Am J Physiol Heart Circ Physiol. 2015 Sep 15; 309(6):H1048-58. PMID: 26276821; PMCID: PMC4591360.
      Citations: 13     Fields:    Translation:AnimalsCells
    72. Cameron SJ, Ture SK, Mickelsen D, Chakrabarti E, Modjeski KL, McNitt S, Seaberry M, Field DJ, Le NT, Abe J, Morrell CN. Platelet Extracellular Regulated Protein Kinase 5 Is a Redox Switch and Triggers Maladaptive Platelet Responses and Myocardial Infarct Expansion. Circulation. 2015 Jul 07; 132(1):47-58. PMID: 25934838; PMCID: PMC4532543.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    73. Lee WR, Sacharidou A, Behling-Kelly E, Oltmann SC, Zhu W, Ahmed M, Gerard RD, Hui DY, Abe J, Shaul PW, Mineo C. PDZK1 prevents neointima formation via suppression of breakpoint cluster region kinase in vascular smooth muscle. PLoS One. 2015; 10(4):e0124494. PMID: 25886360; PMCID: PMC4401672.
      Citations:    Fields:    Translation:Animals
    74. Narumi T, Shishido T, Otaki Y, Kadowaki S, Honda Y, Funayama A, Honda S, Hasegawa H, Kinoshita D, Yokoyama M, Nishiyama S, Takahashi H, Arimoto T, Miyamoto T, Watanabe T, Tanaka A, Woo CH, Abe J, Takeishi Y, Kubota I. High-mobility group box 1-mediated heat shock protein beta 1 expression attenuates mitochondrial dysfunction and apoptosis. J Mol Cell Cardiol. 2015 May; 82:1-12. PMID: 25736854.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    75. Heo KS, Le NT, Cushman HJ, Giancursio CJ, Chang E, Woo CH, Sullivan MA, Taunton J, Yeh ET, Fujiwara K, Abe J. Disturbed flow-activated p90RSK kinase accelerates atherosclerosis by inhibiting SENP2 function. J Clin Invest. 2015 Mar 02; 125(3):1299-310. PMID: 25689261; PMCID: PMC4362265.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    76. Umetsu R, Abe J, Ueda N, Kato Y, Matsui T, Nakayama Y, Kinosada Y, Nakamura M. Association between Selective Serotonin Reuptake Inhibitor Therapy and Suicidality: Analysis of U.S. Food and Drug Administration Adverse Event Reporting System Data. Biol Pharm Bull. 2015; 38(11):1689-99. PMID: 26521821.
      Citations: 16     Fields:    Translation:Humans
    77. Abe J, Berk BC. Novel mechanisms of endothelial mechanotransduction. Arterioscler Thromb Vasc Biol. 2014 Nov; 34(11):2378-86. PMID: 25301843; PMCID: PMC4199910.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    78. Le NT, Takei Y, Izawa-Ishizawa Y, Heo KS, Lee H, Smrcka AV, Miller BL, Ko KA, Ture S, Morrell C, Fujiwara K, Akaike M, Abe J. Identification of activators of ERK5 transcriptional activity by high-throughput screening and the role of endothelial ERK5 in vasoprotective effects induced by statins and antimalarial agents. J Immunol. 2014 Oct 01; 193(7):3803-15. PMID: 25187658; PMCID: PMC4749510.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    79. Nakayama A, Matsuo H, Nakaoka H, Nakamura T, Nakashima H, Takada Y, Oikawa Y, Takada T, Sakiyama M, Shimizu S, Kawamura Y, Chiba T, Abe J, Wakai K, Kawai S, Okada R, Tamura T, Shichijo Y, Akashi A, Suzuki H, Hosoya T, Sakurai Y, Ichida K, Shinomiya N. Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors. Sci Rep. 2014 Jun 09; 4:5227. PMID: 24909660; PMCID: PMC5381477.
      Citations: 39     Fields:    Translation:Humans
    80. Heo KS, Fujiwara K, Abe J. Shear stress and atherosclerosis. Mol Cells. 2014 Jun; 37(6):435-40. PMID: 24781409; PMCID: PMC4086336.
      Citations: 42     Fields:    Translation:HumansCells
    81. Heo KS, Cushman HJ, Akaike M, Woo CH, Wang X, Qiu X, Fujiwara K, Abe J. ERK5 activation in macrophages promotes efferocytosis and inhibits atherosclerosis. Circulation. 2014 Jul 08; 130(2):180-91. PMID: 25001623; PMCID: PMC4439099.
      Citations: 25     Fields:    Translation:AnimalsCells
    82. Maruyama M, Yamamoto T, Abe J, Yodogawa K, Seino Y, Atarashi H, Shimizu W. Number needed to entrain: a new criterion for entrainment mapping in patients with intra-atrial reentrant tachycardia. Circ Arrhythm Electrophysiol. 2014 Jun; 7(3):490-6. PMID: 24762806.
      Citations: 3     Fields:    Translation:Humans
    83. Shum M, Roux PP, Abe J, Smadja-Lam?re N, D?l?ris P, Marette A. Insulin activates RSK (p90 ribosomal S6 kinase) to trigger a new negative feedback loop that regulates insulin signaling for glucose metabolism. J Biol Chem. 2013 Oct 25; 288(43):31165-76. PMID: 24036112; PMCID: PMC3829428.
      Citations: 10     Fields:    Translation:HumansCells
    84. Oikawa M, Wu M, Lim S, Knight WE, Miller CL, Cai Y, Lu Y, Blaxall BC, Takeishi Y, Abe J, Yan C. Cyclic nucleotide phosphodiesterase 3A1 protects the heart against ischemia-reperfusion injury. J Mol Cell Cardiol. 2013 Nov; 64:11-9. PMID: 23988739; PMCID: PMC3869570.
      Citations: 20     Fields:    Translation:AnimalsCells
    85. Abe J, Berk BC. Atheroprone flow activation of the sterol regulatory element binding protein 2 and nod-like receptor protein 3 inflammasome mediates focal atherosclerosis. Circulation. 2013 Aug 06; 128(6):579-82. PMID: 23838164; PMCID: PMC4091715.
      Citations: 15     Fields:    Translation:HumansAnimals
    86. Abe J, Berk BC. Cezanne paints inflammation by regulating ubiquitination. Circ Res. 2013 Jun 07; 112(12):1526-8. PMID: 23743222; PMCID: PMC3782741.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    87. Funayama A, Shishido T, Netsu S, Narumi T, Kadowaki S, Takahashi H, Miyamoto T, Watanabe T, Woo CH, Abe J, Kuwahara K, Nakao K, Takeishi Y, Kubota I. Cardiac nuclear high mobility group box 1 prevents the development of cardiac hypertrophy and heart failure. Cardiovasc Res. 2013 Sep 01; 99(4):657-64. PMID: 23708738; PMCID: PMC3746952.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    88. Abe J, Manabe I, Aikawa M, Aikawa E. Cardiovascular Inflammation 2012: Reactive Oxygen Species, SUMOylation, and Biomarkers in Cardiovascular Inflammation. Int J Inflam. 2013; 2013:953463. PMID: 23555068; PMCID: PMC3608100.
      Citations: 4     
    89. Heo KS, Chang E, Le NT, Cushman H, Yeh ET, Fujiwara K, Abe J. De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis. Circ Res. 2013 Mar 15; 112(6):911-23. PMID: 23381569; PMCID: PMC3697009.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    90. Le NT, Heo KS, Takei Y, Lee H, Woo CH, Chang E, McClain C, Hurley C, Wang X, Li F, Xu H, Morrell C, Sullivan MA, Cohen MS, Serafimova IM, Taunton J, Fujiwara K, Abe J. A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis. Circulation. 2013 Jan 29; 127(4):486-99. PMID: 23243209; PMCID: PMC3574639.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    91. Heo KS, Chang E, Takei Y, Le NT, Woo CH, Sullivan MA, Morrell C, Fujiwara K, Abe J. Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity. Arterioscler Thromb Vasc Biol. 2013 Feb; 33(2):321-9. PMID: 23202365; PMCID: PMC3548065.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    92. Heo KS, Fujiwara K, Abe J. Glucagon-like peptide-1 and its cardiovascular effects. Curr Atheroscler Rep. 2012 Oct; 14(5):422-8. PMID: 22878937.
      Citations: 8     Fields:    Translation:HumansAnimals
    93. Kim GY, Nigro P, Fujiwara K, Abe J, Berk BC. p62 binding to protein kinase C ? regulates tumor necrosis factor a-induced apoptotic pathway in endothelial cells. Arterioscler Thromb Vasc Biol. 2012 Dec; 32(12):2974-80. PMID: 23023376; PMCID: PMC4084716.
      Citations: 13     Fields:    Translation:HumansCells
    94. Le NT, Corsetti JP, Dehoff-Sparks JL, Sparks CE, Fujiwara K, Abe J. Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation. Int J Inflam. 2012; 2012:678190. PMID: 22991685; PMCID: PMC3443607.
      Citations: 10     
    95. Le NT, Takei Y, Shishido T, Woo CH, Chang E, Heo KS, Lee H, Lu Y, Morrell C, Oikawa M, McClain C, Wang X, Tournier C, Molina CA, Taunton J, Yan C, Fujiwara K, Patterson C, Yang J, Abe J. p90RSK targets the ERK5-CHIP ubiquitin E3 ligase activity in diabetic hearts and promotes cardiac apoptosis and dysfunction. Circ Res. 2012 Feb 17; 110(4):536-50. PMID: 22267842; PMCID: PMC3306797.
      Citations: 31     Fields:    Translation:AnimalsCells
    96. Heo KS, Fujiwara K, Abe J. Disturbed-flow-mediated vascular reactive oxygen species induce endothelial dysfunction. Circ J. 2011; 75(12):2722-30. PMID: 22076424; PMCID: PMC3620204.
      Citations: 42     Fields:    Translation:HumansCells
    97. Sakai H, Okafuji I, Nishikomori R, Abe J, Izawa K, Kambe N, Yasumi T, Nakahata T, Heike T. The CD40-CD40L axis and IFN-? play critical roles in Langhans giant cell formation. Int Immunol. 2012 Jan; 24(1):5-15. PMID: 22058328.
      Citations: 15     Fields:    Translation:HumansCells
    98. Heo KS, Lee H, Nigro P, Thomas T, Le NT, Chang E, McClain C, Reinhart-King CA, King MR, Berk BC, Fujiwara K, Woo CH, Abe J. PKC? mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation. J Cell Biol. 2011 May 30; 193(5):867-84. PMID: 21624955; PMCID: PMC3105539.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    99. Shi X, Yan C, Nadtochiy SM, Abe J, Brookes PS, Berk BC. p90 ribosomal S6 kinase regulates activity of the renin-angiotensin system: a pathogenic mechanism for ischemia-reperfusion injury. J Mol Cell Cardiol. 2011 Aug; 51(2):272-5. PMID: 21609719; PMCID: PMC3124613.
      Citations: 4     Fields:    Translation:Animals
    100. Nigro P, Abe J, Berk BC. Flow shear stress and atherosclerosis: a matter of site specificity. Antioxid Redox Signal. 2011 Sep 01; 15(5):1405-14. PMID: 21050140; PMCID: PMC3144425.
      Citations: 95     Fields:    Translation:HumansAnimalsCells
    101. Nigro P, Satoh K, O'Dell MR, Soe NN, Cui Z, Mohan A, Abe J, Alexis JD, Sparks JD, Berk BC. Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice. J Exp Med. 2011 Jan 17; 208(1):53-66. PMID: 21173104; PMCID: PMC3023134.
      Citations: 53     Fields:    Translation:AnimalsCells
    102. Chang E, Heo KS, Woo CH, Lee H, Le NT, Thomas TN, Fujiwara K, Abe J. MK2 SUMOylation regulates actin filament remodeling and subsequent migration in endothelial cells by inhibiting MK2 kinase and HSP27 phosphorylation. Blood. 2011 Feb 24; 117(8):2527-37. PMID: 21131586; PMCID: PMC3062414.
      Citations: 26     Fields:    Translation:HumansCells
    103. Jeon KI, Jono H, Miller CL, Cai Y, Lim S, Liu X, Gao P, Abe J, Li JD, Yan C. Ca2+/calmodulin-stimulated PDE1 regulates the beta-catenin/TCF signaling through PP2A B56 gamma subunit in proliferating vascular smooth muscle cells. FEBS J. 2010 Dec; 277(24):5026-39. PMID: 21078118; PMCID: PMC3059601.
      Citations: 20     Fields:    Translation:AnimalsCells
    104. Woo CH, Le NT, Shishido T, Chang E, Lee H, Heo KS, Mickelsen DM, Lu Y, McClain C, Spangenberg T, Yan C, Molina CA, Yang J, Patterson C, Abe J. Novel role of C terminus of Hsc70-interacting protein (CHIP) ubiquitin ligase on inhibiting cardiac apoptosis and dysfunction via regulating ERK5-mediated degradation of inducible cAMP early repressor. FASEB J. 2010 Dec; 24(12):4917-28. PMID: 20724525; PMCID: PMC2992371.
      Citations: 28     Fields:    Translation:AnimalsCells
    105. Nigro P, Abe J, Woo CH, Satoh K, McClain C, O'Dell MR, Lee H, Lim JH, Li JD, Heo KS, Fujiwara K, Berk BC. PKCzeta decreases eNOS protein stability via inhibitory phosphorylation of ERK5. Blood. 2010 Sep 16; 116(11):1971-9. PMID: 20538799; PMCID: PMC3173991.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    106. Jeon KI, Xu X, Aizawa T, Lim JH, Jono H, Kwon DS, Abe J, Berk BC, Li JD, Yan C. Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism. Proc Natl Acad Sci U S A. 2010 May 25; 107(21):9795-800. PMID: 20448200; PMCID: PMC2906898.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    107. Abe J, Yan C. CCN notch signaling in vascular smooth muscle cells: good or bad? Arterioscler Thromb Vasc Biol. 2010 Apr; 30(4):667-8. PMID: 20237327; PMCID: PMC3008587.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    108. Kimura TE, Jin J, Zi M, Prehar S, Liu W, Oceandy D, Abe J, Neyses L, Weston AH, Cartwright EJ, Wang X. Targeted deletion of the extracellular signal-regulated protein kinase 5 attenuates hypertrophic response and promotes pressure overload-induced apoptosis in the heart. Circ Res. 2010 Mar 19; 106(5):961-70. PMID: 20075332; PMCID: PMC3003662.
      Citations: 40     Fields:    Translation:AnimalsCells
    109. Woo CH, Abe J. SUMO--a post-translational modification with therapeutic potential? Curr Opin Pharmacol. 2010 Apr; 10(2):146-55. PMID: 20079693; PMCID: PMC3000872.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    110. Miller CL, Oikawa M, Cai Y, Wojtovich AP, Nagel DJ, Xu X, Xu H, Florio V, Rybalkin SD, Beavo JA, Chen YF, Li JD, Blaxall BC, Abe J, Yan C. Role of Ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase 1 in mediating cardiomyocyte hypertrophy. Circ Res. 2009 Nov 06; 105(10):956-64. PMID: 19797176; PMCID: PMC2803071.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    111. Xie S, Lee YF, Kim E, Chen LM, Ni J, Fang LY, Liu S, Lin SJ, Abe J, Berk B, Ho FM, Chang C. TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation. Proc Natl Acad Sci U S A. 2009 Aug 11; 106(32):13353-8. PMID: 19666541; PMCID: PMC2726407.
      Citations: 48     Fields:    Translation:AnimalsCells
    112. Satoh K, Nigro P, Matoba T, O'Dell MR, Cui Z, Shi X, Mohan A, Yan C, Abe J, Illig KA, Berk BC. Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms. Nat Med. 2009 Jun; 15(6):649-56. PMID: 19430489; PMCID: PMC2704983.
      Citations: 137     Fields:    Translation:Animals
    113. Abe J, Woo CH. NADPH oxidase in vascular injury: a new insight about its regulation and role in T cells. Circ Res. 2009 Jan 30; 104(2):147-9. PMID: 19179667; PMCID: PMC2731553.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    114. Alexis JD, Wang N, Che W, Lerner-Marmarosh N, Sahni A, Korshunov VA, Zou Y, Ding B, Yan C, Berk BC, Abe J. Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells. Circ Res. 2009 Jan 02; 104(1):69-78. PMID: 19023129; PMCID: PMC2642522.
      Citations: 25     Fields:    Translation:AnimalsCells
    115. Lu Z, Abe J, Taunton J, Lu Y, Shishido T, McClain C, Yan C, Xu SP, Spangenberg TM, Xu H. Reactive oxygen species-induced activation of p90 ribosomal S6 kinase prolongs cardiac repolarization through inhibiting outward K+ channel activity. Circ Res. 2008 Aug 01; 103(3):269-78. PMID: 18599872; PMCID: PMC2631445.
      Citations: 25     Fields:    Translation:AnimalsCells
    116. Satoh K, Matoba T, Suzuki J, O'Dell MR, Nigro P, Cui Z, Mohan A, Pan S, Li L, Jin ZG, Yan C, Abe J, Berk BC. Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation. Circulation. 2008 Jun 17; 117(24):3088-98. PMID: 18541741; PMCID: PMC2775430.
      Citations: 68     Fields:    Translation:Animals
    117. Shishido T, Woo CH, Ding B, McClain C, Molina CA, Yan C, Yang J, Abe J. Effects of MEK5/ERK5 association on small ubiquitin-related modification of ERK5: implications for diabetic ventricular dysfunction after myocardial infarction. Circ Res. 2008 Jun 06; 102(11):1416-25. PMID: 18467627; PMCID: PMC2614366.
      Citations: 41     Fields:    Translation:AnimalsCells
    118. Li L, Tatake RJ, Natarajan K, Taba Y, Garin G, Tai C, Leung E, Surapisitchat J, Yoshizumi M, Yan C, Abe J, Berk BC. Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells. Biochem Biophys Res Commun. 2008 May 23; 370(1):159-63. PMID: 18358237; PMCID: PMC2435412.
      Citations: 19     Fields:    Translation:AnimalsCells
    119. Woo CH, Shishido T, McClain C, Lim JH, Li JD, Yang J, Yan C, Abe J. Extracellular signal-regulated kinase 5 SUMOylation antagonizes shear stress-induced antiinflammatory response and endothelial nitric oxide synthase expression in endothelial cells. Circ Res. 2008 Mar 14; 102(5):538-45. PMID: 18218985.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    120. Pawlinski R, Tencati M, Hampton CR, Shishido T, Bullard TA, Casey LM, Andrade-Gordon P, Kotzsch M, Spring D, Luther T, Abe J, Pohlman TH, Verrier ED, Blaxall BC, Mackman N. Protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy. Circulation. 2007 Nov 13; 116(20):2298-306. PMID: 17967980; PMCID: PMC2848478.
      Citations: 61     Fields:    Translation:AnimalsCells
    121. Abe J. Role of PKCs and NF-kappaB activation in myocardial inflammation: enemy or ally? J Mol Cell Cardiol. 2007 Oct; 43(4):404-8. PMID: 17707396.
      Citations: 8     Fields:    Translation:AnimalsCells
    122. Garin G, Abe J, Mohan A, Lu W, Yan C, Newby AC, Rhaman A, Berk BC. Flow antagonizes TNF-alpha signaling in endothelial cells by inhibiting caspase-dependent PKC zeta processing. Circ Res. 2007 Jul 06; 101(1):97-105. PMID: 17525369.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    123. Yan C, Miller CL, Abe J. Regulation of phosphodiesterase 3 and inducible cAMP early repressor in the heart. Circ Res. 2007 Mar 02; 100(4):489-501. PMID: 17332439; PMCID: PMC4115784.
      Citations: 38     Fields:    Translation:HumansAnimals
    124. Yan C, Ding B, Shishido T, Woo CH, Itoh S, Jeon KI, Liu W, Xu H, McClain C, Molina CA, Blaxall BC, Abe J. Activation of extracellular signal-regulated kinase 5 reduces cardiac apoptosis and dysfunction via inhibition of a phosphodiesterase 3A/inducible cAMP early repressor feedback loop. Circ Res. 2007 Mar 02; 100(4):510-9. PMID: 17272811; PMCID: PMC4115673.
      Citations: 34     Fields:    Translation:AnimalsCells
    125. Goubaeva F, Mikami M, Giardina S, Ding B, Abe J, Yang J. Cardiac mitochondrial connexin 43 regulates apoptosis. Biochem Biophys Res Commun. 2007 Jan 05; 352(1):97-103. PMID: 17107662; PMCID: PMC1829482.
      Citations: 38     Fields:    Translation:AnimalsCells
    126. Woo CH, Massett MP, Shishido T, Itoh S, Ding B, McClain C, Che W, Vulapalli SR, Yan C, Abe J. ERK5 activation inhibits inflammatory responses via peroxisome proliferator-activated receptor delta (PPARdelta) stimulation. J Biol Chem. 2006 Oct 27; 281(43):32164-74. PMID: 16943204.
      Citations: 48     Fields:    Translation:AnimalsCells
    127. Abe J, Iozzo RV, Laplante P, Raymond MA, Labelle A, H?bert MJ. Perlecan proteolysis induces an alpha2beta1 integrin- and Src family kinase-dependent anti-apoptotic pathway in fibroblasts in the absence of focal adhesion kinase activation. J Biol Chem. 2006 Oct 13; 281(41):30383-92. PMID: 16882656.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    128. Abe J. Bone morphogenetic protein (BMP) family, SMAD signaling and Id helix-loop-helix proteins in the vasculature: the continuous mystery of BMPs pleotropic effects. J Mol Cell Cardiol. 2006 Jul; 41(1):4-7. PMID: 16762360.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    129. Maekawa N, Abe J, Shishido T, Itoh S, Ding B, Sharma VK, Sheu SS, Blaxall BC, Berk BC. Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury. Circulation. 2006 May 30; 113(21):2516-23. PMID: 16717153.
      Citations: 27     Fields:    Translation:AnimalsCells
    130. Shishido T, Nozaki N, Takahashi H, Arimoto T, Niizeki T, Koyama Y, Abe J, Takeishi Y, Kubota I. Central role of endogenous Toll-like receptor-2 activation in regulating inflammation, reactive oxygen species production, and subsequent neointimal formation after vascular injury. Biochem Biophys Res Commun. 2006 Jul 14; 345(4):1446-53. PMID: 16730663.
      Citations: 26     Fields:    Translation:Animals
    131. Itoh S, Ding B, Shishido T, Lerner-Marmarosh N, Wang N, Maekawa N, Berk BC, Takeishi Y, Yan C, Blaxall BC, Abe J. Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium. Circulation. 2006 Apr 11; 113(14):1787-98. PMID: 16585392.
      Citations: 19     Fields:    Translation:Animals
    132. Uno M, Abe J, Sawai C, Sakaue Y, Nishitani A, Yasuda Y, Tsuzuki K, Takano T, Ohno M, Maruyama T, Takeuchi Y. Effect of additional auditory and visual stimuli on continuous performance test (noise-generated CPT) in AD/HD children -- usefulness of noise-generated CPT. Brain Dev. 2006 Apr; 28(3):162-9. PMID: 16466882.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    133. Arimoto T, Takeishi Y, Takahashi H, Shishido T, Niizeki T, Koyama Y, Shiga R, Nozaki N, Nakajima O, Nishimaru K, Abe J, Endoh M, Walsh RA, Goto K, Kubota I. Cardiac-specific overexpression of diacylglycerol kinase zeta prevents Gq protein-coupled receptor agonist-induced cardiac hypertrophy in transgenic mice. Circulation. 2006 Jan 03; 113(1):60-6. PMID: 16380548.
      Citations: 31     Fields:    Translation:AnimalsCells
    134. Ding B, Abe J, Wei H, Xu H, Che W, Aizawa T, Liu W, Molina CA, Sadoshima J, Blaxall BC, Berk BC, Yan C. A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis. Proc Natl Acad Sci U S A. 2005 Oct 11; 102(41):14771-6. PMID: 16186489; PMCID: PMC1253575.
      Citations: 60     Fields:    Translation:AnimalsCells
    135. Pi X, Garin G, Xie L, Zheng Q, Wei H, Abe J, Yan C, Berk BC. BMK1/ERK5 is a novel regulator of angiogenesis by destabilizing hypoxia inducible factor 1alpha. Circ Res. 2005 Jun 10; 96(11):1145-51. PMID: 15879308.
      Citations: 29     Fields:    Translation:AnimalsCells
    136. Ding B, Abe JI, Wei H, Huang Q, Walsh RA, Molina CA, Zhao A, Sadoshima J, Blaxall BC, Berk BC, Yan C. Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure. Circulation. 2005 May 17; 111(19):2469-2476. PMID: 15867171; PMCID: PMC4108189.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    137. Itoh S, Lemay S, Osawa M, Che W, Duan Y, Tompkins A, Brookes PS, Sheu SS, Abe J. Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells. J Biol Chem. 2005 Jul 15; 280(28):26383-96. PMID: 15855164.
      Citations: 23     Fields:    Translation:AnimalsCells
    138. Itoh S, Ding B, Bains CP, Wang N, Takeishi Y, Jalili T, King GL, Walsh RA, Yan C, Abe J. Role of p90 ribosomal S6 kinase (p90RSK) in reactive oxygen species and protein kinase C beta (PKC-beta)-mediated cardiac troponin I phosphorylation. J Biol Chem. 2005 Jun 24; 280(25):24135-42. PMID: 15840586.
      Citations: 29     Fields:    Translation:AnimalsCells
    139. Takahashi H, Takeishi Y, Seidler T, Arimoto T, Akiyama H, Hozumi Y, Koyama Y, Shishido T, Tsunoda Y, Niizeki T, Nozaki N, Abe J, Hasenfuss G, Goto K, Kubota I. Adenovirus-mediated overexpression of diacylglycerol kinase-zeta inhibits endothelin-1-induced cardiomyocyte hypertrophy. Circulation. 2005 Mar 29; 111(12):1510-6. PMID: 15781737.
      Citations: 17     Fields:    Translation:AnimalsCells
    140. Akaike M, Che W, Marmarosh NL, Ohta S, Osawa M, Ding B, Berk BC, Yan C, Abe J. The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation in endothelial cells. Mol Cell Biol. 2004 Oct; 24(19):8691-704. PMID: 15367687; PMCID: PMC516745.
      Citations: 62     Fields:    Translation:HumansCells
    141. Cameron SJ, Itoh S, Baines CP, Zhang C, Ohta S, Che W, Glassman M, Lee JD, Yan C, Yang J, Abe J. Activation of big MAP kinase 1 (BMK1/ERK5) inhibits cardiac injury after myocardial ischemia and reperfusion. FEBS Lett. 2004 May 21; 566(1-3):255-60. PMID: 15147905.
      Citations: 19     Fields:    Translation:AnimalsCells
    142. Osawa M, Itoh S, Ohta S, Huang Q, Berk BC, Marmarosh NL, Che W, Ding B, Yan C, Abe J. ERK1/2 associates with the c-Met-binding domain of growth factor receptor-bound protein 2 (Grb2)-associated binder-1 (Gab1): role in ERK1/2 and early growth response factor-1 (Egr-1) nuclear accumulation. J Biol Chem. 2004 Jul 09; 279(28):29691-9. PMID: 15078886.
      Citations: 16     Fields:    Translation:AnimalsCells
    143. Bedirian A, Baldwin C, Abe J, Takano T, Lemay S. Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells. J Biol Chem. 2004 Apr 30; 279(18):19335-49. PMID: 14963042.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    144. Miyauchi M, Kobayashi Y, Miyauchi Y, Abe J, Morita N, Iwasaki YK, Hayashi M, Takano T. Parasympathetic blockade promotes recovery from atrial electrical remodeling induced by short-term rapid atrial pacing. Pacing Clin Electrophysiol. 2004 Jan; 27(1):33-7. PMID: 14720152.
      Citations:    Fields:    Translation:Humans
    145. Cameron SJ, Abe J, Malik S, Che W, Yang J. Differential role of MEK5alpha and MEK5beta in BMK1/ERK5 activation. J Biol Chem. 2004 Jan 09; 279(2):1506-12. PMID: 14583600.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    146. Lerner-Marmarosh N, Yoshizumi M, Che W, Surapisitchat J, Kawakatsu H, Akaike M, Ding B, Huang Q, Yan C, Berk BC, Abe J. Inhibition of tumor necrosis factor-[alpha]-induced SHP-2 phosphatase activity by shear stress: a mechanism to reduce endothelial inflammation. Arterioscler Thromb Vasc Biol. 2003 Oct 01; 23(10):1775-81. PMID: 12947019.
      Citations: 12     Fields:    Translation:Humans
    147. Aizawa T, Wei H, Miano JM, Abe J, Berk BC, Yan C. Role of phosphodiesterase 3 in NO/cGMP-mediated antiinflammatory effects in vascular smooth muscle cells. Circ Res. 2003 Sep 05; 93(5):406-13. PMID: 12919948.
      Citations: 49     Fields:    Translation:AnimalsCells
    148. Cameron SJ, Malik S, Akaike M, Lerner-Marmarosh N, Yan C, Lee JD, Abe J, Yang J. Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase activation. J Biol Chem. 2003 May 16; 278(20):18682-8. PMID: 12637502.
      Citations: 44     Fields:    Translation:HumansCells
    149. Yoshizumi M, Abe J, Tsuchiya K, Berk BC, Tamaki T. Stress and vascular responses: atheroprotective effect of laminar fluid shear stress in endothelial cells: possible role of mitogen-activated protein kinases. J Pharmacol Sci. 2003 Mar; 91(3):172-6. PMID: 12686737.
      Citations: 18     Fields:    Translation:HumansAnimals
    150. Tai LK, Okuda M, Abe J, Yan C, Berk BC. Fluid shear stress activates proline-rich tyrosine kinase via reactive oxygen species-dependent pathway. Arterioscler Thromb Vasc Biol. 2002 Nov 01; 22(11):1790-6. PMID: 12426206.
      Citations: 24     Fields:    Translation:AnimalsCells
    151. Matsui E, Musti KV, Abe J, Yamasaki K, Matsui I, Harata K. Molecular structure and novel DNA binding sites located in loops of flap endonuclease-1 from Pyrococcus horikoshii. J Biol Chem. 2002 Oct 04; 277(40):37840-7. PMID: 12147694.
      Citations: 11     Fields:    Translation:Cells
    152. Abe J, Berk BC. Hypoxia and HIF-1alpha stability: another stress-sensing mechanism for Shc. Circ Res. 2002 Jul 12; 91(1):4-6. PMID: 12114314.
      Citations: 2     Fields:    Translation:HumansCells
    153. Che W, Lerner-Marmarosh N, Huang Q, Osawa M, Ohta S, Yoshizumi M, Glassman M, Lee JD, Yan C, Berk BC, Abe J. Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression. Circ Res. 2002 Jun 14; 90(11):1222-30. PMID: 12065326.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    154. Huang Q, Lerner-Marmarosh N, Che W, Ohta S, Osawa M, Yoshizumi M, Glassman M, Yan C, Berk BC, Abe J. The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation. J Biol Chem. 2002 Aug 09; 277(32):29330-41. PMID: 12011040.
      Citations: 8     Fields:    Translation:AnimalsCells
    155. Saito Y, Hojo Y, Tanimoto T, Abe J, Berk BC. Protein kinase C-alpha and protein kinase C-epsilon are required for Grb2-associated binder-1 tyrosine phosphorylation in response to platelet-derived growth factor. J Biol Chem. 2002 Jun 28; 277(26):23216-22. PMID: 11940581.
      Citations: 7     Fields:    Translation:AnimalsCells
    156. Takeishi Y, Huang Q, Abe J, Che W, Lee JD, Kawakatsu H, Hoit BD, Berk BC, Walsh RA. Activation of mitogen-activated protein kinases and p90 ribosomal S6 kinase in failing human hearts with dilated cardiomyopathy. Cardiovasc Res. 2002 Jan; 53(1):131-7. PMID: 11744021.
      Citations: 48     Fields:    Translation:HumansCells
    157. Ohno M, Narita T, Abe J, Tsuzuki T, Yagi K, Takikita S, Takano T, Shimada M. Apoptosis in cerebrum of macular mutant mouse. Acta Neuropathol. 2002 Apr; 103(4):356-62. PMID: 11904755.
      Citations: 5     Fields:    Translation:Animals
    158. Berk BC, Abe JI, Min W, Surapisitchat J, Yan C. Endothelial atheroprotective and anti-inflammatory mechanisms. Ann N Y Acad Sci. 2001 Dec; 947:93-109; discussion 109-11. PMID: 11795313.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    159. Abe JI, Che W, Yoshizumi M, Huang Q, Glassman M, Ohta S, Wu Y, Arlinghaus R, Berk BC. Bcr in vascular smooth muscle cells involvement of Ras and Raf-1 activation by Bcr. Ann N Y Acad Sci. 2001 Dec; 947:341-3. PMID: 11795286.
      Citations: 2     Fields:    Translation:Animals
    160. Takeishi Y, Huang Q, Wang T, Glassman M, Yoshizumi M, Baines CP, Lee JD, Kawakatsu H, Che W, Lerner-Marmarosh N, Zhang C, Yan C, Ohta S, Walsh RA, Berk BC, Abe J. Src family kinase and adenosine differentially regulate multiple MAP kinases in ischemic myocardium: modulation of MAP kinases activation by ischemic preconditioning. J Mol Cell Cardiol. 2001 Nov; 33(11):1989-2005. PMID: 11708843.
      Citations: 11     Fields:    Translation:AnimalsCells
    161. Che W, Abe J, Yoshizumi M, Huang Q, Glassman M, Ohta S, Melaragno MG, Poppa V, Yan C, Lerner-Marmarosh N, Zhang C, Wu Y, Arlinghaus R, Berk BC. p160 Bcr mediates platelet-derived growth factor activation of extracellular signal-regulated kinase in vascular smooth muscle cells. Circulation. 2001 Sep 18; 104(12):1399-406. PMID: 11560856.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    162. Takeishi Y, Huang Q, Abe J, Glassman M, Che W, Lee JD, Kawakatsu H, Lawrence EG, Hoit BD, Berk BC, Walsh RA. Src and multiple MAP kinase activation in cardiac hypertrophy and congestive heart failure under chronic pressure-overload: comparison with acute mechanical stretch. J Mol Cell Cardiol. 2001 Sep; 33(9):1637-48. PMID: 11549343.
      Citations: 47     Fields:    Translation:AnimalsCells
    163. Lehoux S, Florian JA, Berk BC. 14-3-3 Binding to Na+/H+ exchanger isoform-1 is associated with serum-dependent activation of Na+/H+ exchange. J Biol Chem. 2001 May 11; 276(19):15794-800. PMID: 11279064.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    164. Yan C, Luo H, Lee JD, Abe J, Berk BC. Molecular cloning of mouse ERK5/BMK1 splice variants and characterization of ERK5 functional domains. J Biol Chem. 2001 Apr 06; 276(14):10870-8. PMID: 11139578.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    165. Yoshizumi M, Abe J, Haendeler J, Huang Q, Berk BC. Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species. J Biol Chem. 2000 Apr 21; 275(16):11706-12. PMID: 10766791.
      Citations: 49     Fields:    Translation:AnimalsCells
    166. Abe Ji, Baines CP, Berk BC. Role of mitogen-activated protein kinases in ischemia and reperfusion injury : the good and the bad. Circ Res. 2000 Mar 31; 86(6):607-9. PMID: 10746992.
      Citations: 30     Fields:    Translation:HumansAnimals
    167. Abe J, Okuda M, Huang Q, Yoshizumi M, Berk BC. Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras. J Biol Chem. 2000 Jan 21; 275(3):1739-48. PMID: 10636870.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    168. Takeishi Y, Abe Ji, Lee JD, Kawakatsu H, Walsh RA, Berk BC. Differential regulation of p90 ribosomal S6 kinase and big mitogen-activated protein kinase 1 by ischemia/reperfusion and oxidative stress in perfused guinea pig hearts. Circ Res. 1999 Dec 3-17; 85(12):1164-72. PMID: 10590243.
      Citations: 29     Fields:    Translation:Animals
    169. Abe J, Berk BC. Fyn and JAK2 mediate Ras activation by reactive oxygen species. J Biol Chem. 1999 Jul 23; 274(30):21003-10. PMID: 10409649.
      Citations: 37     Fields:    Translation:AnimalsCells
    170. Takahashi E, Abe J, Gallis B, Aebersold R, Spring DJ, Krebs EG, Berk BC. p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1. J Biol Chem. 1999 Jul 16; 274(29):20206-14. PMID: 10400637.
      Citations: 82     Fields:    Translation:AnimalsCells
    171. Deguchi J, Namba T, Hamada H, Nakaoka T, Abe J, Sato O, Miyata T, Makuuchi M, Kurokawa K, Takuwa Y. Targeting endogenous platelet-derived growth factor B-chain by adenovirus-mediated gene transfer potently inhibits in vivo smooth muscle proliferation after arterial injury. Gene Ther. 1999 Jun; 6(6):956-65. PMID: 10455397.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    172. Deguchi J, Abe J, Makuuchi M, Takuwa Y. Inhibitory effects of trapidil on PDGF signaling in balloon-injured rat carotid artery. Life Sci. 1999; 65(26):2791-9. PMID: 10622268.
      Citations: 1     Fields:    Translation:AnimalsCells
    173. Kusuhara M, Takahashi E, Peterson TE, Abe J, Ishida M, Han J, Ulevitch R, Berk BC. p38 Kinase is a negative regulator of angiotensin II signal transduction in vascular smooth muscle cells: effects on Na+/H+ exchange and ERK1/2. Circ Res. 1998 Oct 19; 83(8):824-31. PMID: 9776729.
      Citations: 27     Fields:    Translation:AnimalsCells
    174. Abe J, Deguchi J, Takuwa Y, Hara K, Ikari Y, Tamura T, Ohno M, Kurokawa K. Tyrosine phosphorylation of platelet derived growth factor beta receptors in coronary artery lesions: implications for vascular remodelling after directional coronary atherectomy and unstable angina pectoris. Heart. 1998 Apr; 79(4):400-6. PMID: 9616351; PMCID: PMC1728674.
      Citations: 6     Fields:    Translation:HumansCells
    175. Abe J, Berk BC. Reactive oxygen species as mediators of signal transduction in cardiovascular disease. Trends Cardiovasc Med. 1998 Feb; 8(2):59-64. PMID: 21235913.
      Citations: 41     Fields:    
    176. Abe J, Deguchi J, Matsumoto T, Takuwa N, Noda M, Ohno M, Makuuchi M, Kurokawa K, Takuwa Y. Stimulated activation of platelet-derived growth factor receptor in vivo in balloon-injured arteries: a link between angiotensin II and intimal thickening. Circulation. 1997 Sep 16; 96(6):1906-13. PMID: 9323080.
      Citations: 11     Fields:    Translation:AnimalsCells
    177. Abe Ji, Takahashi M, Ishida M, Lee JD, Berk BC. c-Src is required for oxidative stress-mediated activation of big mitogen-activated protein kinase 1. J Biol Chem. 1997 Aug 15; 272(33):20389-94. PMID: 9252345.
      Citations: 71     Fields:    Translation:AnimalsCells
    178. Takahashi E, Abe J, Berk BC. Angiotensin II stimulates p90rsk in vascular smooth muscle cells. A potential Na(+)-H+ exchanger kinase. Circ Res. 1997 Aug; 81(2):268-73. PMID: 9242188.
      Citations: 21     Fields:    Translation:AnimalsCells
    179. Shiojima I, Ikari Y, Abe J, Ishizaka N, Maemura K, Kurihara H, Isshiki TA, Suma H, Saeki H, Hara K, Tamura T, Yamaguchi T. Thrombotic occlusion of the coronary artery associated with accidental detachment of undeployed Palmaz-Schatz stent. Cathet Cardiovasc Diagn. 1996 Aug; 38(4):360-2. PMID: 8853142.
      Citations:    Fields:    Translation:Humans
    180. Abe J, Kusuhara M, Ulevitch RJ, Berk BC, Lee JD. Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase. J Biol Chem. 1996 Jul 12; 271(28):16586-90. PMID: 8663194.
      Citations: 120     Fields:    Translation:HumansAnimalsCells
    181. Abe J, Zhou W, Takuwa N, Taguchi J, Kurokawa K, Kumada M, Takuwa Y. A fumagillin derivative angiogenesis inhibitor, AGM-1470, inhibits activation of cyclin-dependent kinases and phosphorylation of retinoblastoma gene product but not protein tyrosyl phosphorylation or protooncogene expression in vascular endothelial cells. Cancer Res. 1994 Jul 01; 54(13):3407-12. PMID: 8012959.
      Citations: 28     Fields:    Translation:HumansCells
    182. Abe J, Zhou W, Taguchi J, Takuwa N, Miki K, Okazaki H, Kurokawa K, Kumada M, Takuwa Y. Suppression of neointimal smooth muscle cell accumulation in vivo by antisense cdc2 and cdk2 oligonucleotides in rat carotid artery. Biochem Biophys Res Commun. 1994 Jan 14; 198(1):16-24. PMID: 8292019.
      Citations: 14     Fields:    Translation:AnimalsCells
    183. Ishizaka N, Issiki T, Saeki F, Ishizaka Y, Ikari Y, Abe J, Soumitsu Y, Hashimoto H, Masaki K, Yamaguchi T. Angiographic follow-up after successful percutaneous coronary angioplasty for chronic total coronary occlusion: experience in 110 consecutive patients. Am Heart J. 1994 Jan; 127(1):8-12. PMID: 8273760.
      Citations: 7     Fields:    Translation:Humans
    184. Taguchi J, Abe J, Ohno M, Schwartz SM, Kurokawa K. Topical application of AT1 receptor antagonists prevents medial and neointimal proliferation after balloon injury. Blood Press Suppl. 1994; 5:38-42. PMID: 7889199.
      Citations:    Fields:    Translation:Animals
    185. Taguchi J, Abe J, Okazaki H, Ochiai M, Ohno M, Takuwa Y, Kurokawa K. Angiotensin converting enzyme inhibitors or DuP753 prevent neointimal formation following balloon injury with single topical or multiple systemic application. Biochem Biophys Res Commun. 1993 Oct 29; 196(2):969-74. PMID: 8240375.
      Citations:    Fields:    Translation:Animals
    186. Abe J, Yamaguchi T, Isshiki T, Naka H, Taguchi J, Ishizaka N, Kurokawa K, Saeki F, Ishizaka Y, Ui K, et al. Myocardial reperfusion can be predicted by myoglobin/creatine kinase ratio of a single blood sample obtained at the time of admission. Am Heart J. 1993 Aug; 126(2):279-85. PMID: 8337996.
      Citations: 2     Fields:    Translation:Humans
    187. Taguchi J, Abe J, Okazaki H, Takuwa Y, Kurokawa K. L-arginine inhibits neointimal formation following balloon injury. Life Sci. 1993; 53(23):PL387-92. PMID: 8246666.
      Citations: 2     Fields:    Translation:Animals
    188. Abe J, Yamaguchi T, Isshiki T, Naka H, Kawada Y, Katayama Y. Rapid quantitation of serum myoglobin by latex agglutination turbidimetry. Clin Chim Acta. 1991 Nov 09; 203(1):95-6. PMID: 1769124.
      Citations:    Fields:    Translation:Humans
    189. Role for SUMOylation in disturbed flow-induced atherosclerotic plaque formation. Biomedical Engineering Letters. 5:162-171.
    190. The Future of Onco-Cardiology. Circulation Research. 119:896-899.
    191. Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events. Antioxidants and Redox Signaling. 25:435-450.
    192. Multiple functions of protein inhibitor of activated STAT1 in regulating endothelial cell proliferation and inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 36:1717-1719.
    193. Flow signaling and atherosclerosis. Cellular and Molecular Life Sciences. 1-24.
    194. PDE1C deficiency antagonizes pathological cardiac remodeling and dysfunction. Proceedings of the National Academy of Sciences of the United States of America. 113:E7116-E7125.
    195. PDZK1 prevents neointima formation via suppression of breakpoint cluster region kinase in vascular smooth muscle. PLoS One. 10.
    196. Reactive oxygen species, SUMOylation, and endothelial inflammation. International Journal of Inflammation. 2012.
    197. Corrigendum to p90 ribosomal S6 kinase regulates activity of the renin-angiotensin system. Journal of Molecular and Cellular Cardiology. 52:292.
    198. Angiotensin II Stimulates p90rsk2 in vascular smooth muscle cells. FASEB Journal. 11.
    199. Response to letter regarding article, "protease-activated receptor-1 contributes to cardiac remodeling and hypertrophy". Circulation. 117.
    200. Pyroptosis as a Regulated Form of Necrosis. Circulation Research. 118:1457-1460.
    201. Shear stress-mediated signal transduction. 39-68.
    202. Response to letter regarding article, "role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemia and diabetic myocardium" [2]. Circulation. 114.
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