HELEN PIWNICA-WORMS to Phosphorylation
This is a "connection" page, showing publications HELEN PIWNICA-WORMS has written about Phosphorylation.
Connection Strength
1.134
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Phosphorylation of the E3 ubiquitin ligase RNF41 by the kinase Par-1b is required for epithelial cell polarity. J Cell Sci. 2014 Jan 15; 127(Pt 2):315-27.
Score: 0.064
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Casein kinase 1 functions as both penultimate and ultimate kinase in regulating Cdc25A destruction. Oncogene. 2010 Jun 10; 29(23):3324-34.
Score: 0.050
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DDB1 targets Chk1 to the Cul4 E3 ligase complex in normal cycling cells and in cells experiencing replication stress. Cancer Res. 2009 Mar 15; 69(6):2630-7.
Score: 0.046
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Phosphorylation of the Par-1 polarity kinase by protein kinase D regulates 14-3-3 binding and membrane association. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18378-83.
Score: 0.045
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Regulation of Chk2 ubiquitination and signaling through autophosphorylation of serine 379. Mol Cell Biol. 2008 Oct; 28(19):5874-85.
Score: 0.044
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GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers. Cancer Cell. 2008 Jan; 13(1):36-47.
Score: 0.043
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Phosphorylation of Chk1 by ATR is antagonized by a Chk1-regulated protein phosphatase 2A circuit. Mol Cell Biol. 2006 Oct; 26(20):7529-38.
Score: 0.039
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Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity. Curr Biol. 2004 Apr 20; 14(8):736-41.
Score: 0.033
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Chk1 kinase negatively regulates mitotic function of Cdc25A phosphatase through 14-3-3 binding. Mol Cell Biol. 2003 Nov; 23(21):7488-97.
Score: 0.032
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Cdc25A regulation: to destroy or not to destroy--is that the only question? Cell Cycle. 2003 Sep-Oct; 2(5):455-7.
Score: 0.032
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Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation. Mol Cancer Res. 2003 Jun; 1(8):598-609.
Score: 0.031
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Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):14795-800.
Score: 0.030
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14-3-3 binding regulates catalytic activity of human Wee1 kinase. Cell Growth Differ. 2001 Dec; 12(12):581-9.
Score: 0.028
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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol. 2001 Jul; 21(13):4129-39.
Score: 0.027
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The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01. J Biol Chem. 2000 Feb 25; 275(8):5600-5.
Score: 0.025
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Ca2+-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection. Mol Cell. 2019 06 20; 74(6):1123-1137.e6.
Score: 0.023
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Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1. Mol Cell. 2018 08 16; 71(4):606-620.e7.
Score: 0.022
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C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding. Cell Growth Differ. 1998 Mar; 9(3):197-208.
Score: 0.022
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Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science. 1997 Sep 05; 277(5331):1501-5.
Score: 0.021
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The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex. Mol Cell Biol. 1997 Feb; 17(2):571-83.
Score: 0.020
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Reversible phosphorylation and mitotic control. J Lab Clin Med. 1996 Oct; 128(4):350-4.
Score: 0.020
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Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth. Oncogene. 2016 11 17; 35(46):5977-5988.
Score: 0.019
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Identification of a 95-kDa WEE1-like tyrosine kinase in HeLa cells. Proc Natl Acad Sci U S A. 1995 Oct 10; 92(21):9638-42.
Score: 0.018
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Subcellular localization and Ser-137 phosphorylation regulate tumor-suppressive activity of profilin-1. J Biol Chem. 2015 Apr 03; 290(14):9075-86.
Score: 0.018
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Purification of a serine kinase that associates with and phosphorylates human Cdc25C on serine 216. J Biol Chem. 1994 Dec 02; 269(48):30461-9.
Score: 0.017
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mik1+ encodes a tyrosine kinase that phosphorylates p34cdc2 on tyrosine 15. J Biol Chem. 1994 Dec 02; 269(48):30530-7.
Score: 0.017
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Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol Cell Biol. 1994 Dec; 14(12):8420-31.
Score: 0.017
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Cell cycle regulation of the p34cdc2 inhibitory kinases. Mol Biol Cell. 1994 Sep; 5(9):989-1001.
Score: 0.017
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Reversible tyrosine phosphorylation and cell cycle control. Semin Cell Biol. 1993 Dec; 4(6):433-42.
Score: 0.016
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Phosphorylation and inactivation of the mitotic inhibitor Wee1 by the nim1/cdr1 kinase. Nature. 1993 Jun 24; 363(6431):736-8.
Score: 0.016
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Mechanisms of p34cdc2 regulation. Mol Cell Biol. 1993 Mar; 13(3):1675-85.
Score: 0.015
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Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase. Science. 1992 Sep 25; 257(5078):1955-7.
Score: 0.015
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p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):2917-21.
Score: 0.014
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cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2. Mol Biol Cell. 1992 Jan; 3(1):73-84.
Score: 0.014
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Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+ dependent manner. EMBO J. 1991 May; 10(5):1255-63.
Score: 0.013
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p107wee1 is a serine/threonine and tyrosine kinase that promotes the tyrosine phosphorylation of the cyclin/p34cdc2 complex. Cold Spring Harb Symp Quant Biol. 1991; 56:567-76.
Score: 0.013
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Regulation of pp60c-src and its interaction with polyomavirus middle T antigen in insect cells. J Virol. 1990 Jan; 64(1):61-8.
Score: 0.012
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The polarity protein Par1b/EMK/MARK2 regulates T cell receptor-induced microtubule-organizing center polarization. J Immunol. 2009 Jul 15; 183(2):1215-21.
Score: 0.012
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Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication. Cell Host Microbe. 2007 Jun 14; 1(4):275-86.
Score: 0.010
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Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src. Cell. 1987 Apr 10; 49(1):75-82.
Score: 0.010
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Identification of protein phosphorylation sites within Ser/Thr-rich cluster domains using site-directed mutagenesis and hybrid linear quadrupole ion trap Fourier transform ion cyclotron resonance mass spectrometry. Rapid Commun Mass Spectrom. 2007; 21(21):3443-51.
Score: 0.010
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New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases. Mol Cell Biol. 2006 Oct; 26(19):7086-102.
Score: 0.010
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Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarity. Proc Natl Acad Sci U S A. 2006 May 30; 103(22):8534-9.
Score: 0.010
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Accurate mass-driven analysis for the characterization of protein phosphorylation. Study of the human Chk2 protein kinase. Anal Chem. 2006 Apr 01; 78(7):2171-81.
Score: 0.009
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Lack of PTEN sequesters CHK1 and initiates genetic instability. Cancer Cell. 2005 Feb; 7(2):193-204.
Score: 0.009
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Dual phosphorylation controls Cdc25 phosphatases and mitotic entry. Nat Cell Biol. 2003 Jun; 5(6):545-51.
Score: 0.008
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Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):1990-5.
Score: 0.007
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C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1. Mol Cell. 2001 Nov; 8(5):983-93.
Score: 0.007
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The human decatenation checkpoint. Proc Natl Acad Sci U S A. 2001 Oct 09; 98(21):12044-9.
Score: 0.007
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New perspectives on Raf-1: the involvement of p21ras in the activation of Raf-1 and a potential role for Raf-1 in events occurring later in the cell cycle. Cold Spring Harb Symp Quant Biol. 1991; 56:251-63.
Score: 0.007
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Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Res. 2000 Nov 01; 60(21):5934-6.
Score: 0.007
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Replication checkpoint requires phosphorylation of the phosphatase Cdc25 by Cds1 or Chk1. Nature. 1998 Oct 01; 395(6701):507-10.
Score: 0.006
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14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity. Mol Cell Biol. 1998 Sep; 18(9):5229-38.
Score: 0.006
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Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3beta protein. J Biol Chem. 1997 Oct 24; 272(43):27281-7.
Score: 0.005
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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science. 1997 Sep 05; 277(5331):1497-501.
Score: 0.005
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Use of an oriented peptide library to determine the optimal substrates of protein kinases. Curr Biol. 1994 Nov 01; 4(11):973-82.
Score: 0.004
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Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5. FEBS Lett. 1993 Dec 28; 336(3):417-24.
Score: 0.004
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Purification and biochemical characterization of non-myristoylated recombinant pp60c-src kinase. Biochem J. 1992 Nov 01; 287 ( Pt 3):985-93.
Score: 0.004
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Cdc25 regulates the phosphorylation and activity of the Xenopus cdk2 protein kinase complex. J Biol Chem. 1992 Sep 05; 267(25):18040-6.
Score: 0.004
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Maturation-specific polyadenylation: in vitro activation by p34cdc2 and phosphorylation of a 58-kD CPE-binding protein. Genes Dev. 1991 Sep; 5(9):1697-708.
Score: 0.003
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Tyrosine phosphorylation of the gap junction protein connexin43 is required for the pp60v-src-induced inhibition of communication. Cell Regul. 1990 Dec; 1(13):989-1002.
Score: 0.003
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cdc2 gene expression at the G1 to S transition in human T lymphocytes. Science. 1990 Nov 09; 250(4982):805-8.
Score: 0.003
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Tyrosine phosphorylation is a signal for the trafficking of pp85, an 85-kDa phosphorylated polypeptide associated with phosphatidylinositol kinase activity. Proc Natl Acad Sci U S A. 1990 Jun; 87(12):4458-62.
Score: 0.003
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The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell. 1989 Sep 22; 58(6):1085-95.
Score: 0.003
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The carboxy terminus of pp60c-src is a regulatory domain and is involved in complex formation with the middle-T antigen of polyomavirus. Mol Cell Biol. 1988 Apr; 8(4):1736-47.
Score: 0.003
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Tyrosine phosphorylation in signal transduction. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 1:161-71.
Score: 0.003
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Differentiation of myeloid cells is accompanied by increased levels of pp60c-src protein and kinase activity. Proc Natl Acad Sci U S A. 1986 Jul; 83(14):5131-5.
Score: 0.002