Connection

HELEN PIWNICA-WORMS to Female

This is a "connection" page, showing publications HELEN PIWNICA-WORMS has written about Female.
Connection Strength

0.359
  1. Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast. Nat Commun. 2021 08 18; 12(1):5024.
    View in: PubMed
    Score: 0.022
  2. Pharmacologic profiling of patient-derived xenograft models of primary treatment-na?ve triple-negative breast cancer. Sci Rep. 2020 10 21; 10(1):17899.
    View in: PubMed
    Score: 0.021
  3. Fasting Reduces Intestinal Radiotoxicity, Enabling Dose-Escalated Radiation Therapy for Pancreatic Cancer. Int J Radiat Oncol Biol Phys. 2019 11 01; 105(3):537-547.
    View in: PubMed
    Score: 0.019
  4. Resistance to neoadjuvant chemotherapy in triple-negative breast cancer mediated by a reversible drug-tolerant state. Sci Transl Med. 2019 04 17; 11(488).
    View in: PubMed
    Score: 0.019
  5. High-resolution clonal mapping of multi-organ metastasis in triple negative breast cancer. Nat Commun. 2018 11 29; 9(1):5079.
    View in: PubMed
    Score: 0.018
  6. Stem cell enriched-epithelial spheroid cultures for rapidly assaying small intestinal radioprotectors and radiosensitizers in vitro. Sci Rep. 2018 10 18; 8(1):15410.
    View in: PubMed
    Score: 0.018
  7. Intratumoral Heterogeneity in Ductal Carcinoma In Situ: Chaos and Consequence. J Mammary Gland Biol Neoplasia. 2018 12; 23(4):191-205.
    View in: PubMed
    Score: 0.018
  8. p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer. Breast Cancer Res. 2016 Jan 27; 18(1):13.
    View in: PubMed
    Score: 0.015
  9. Fasting protects mice from lethal DNA damage by promoting small intestinal epithelial stem cell survival. Proc Natl Acad Sci U S A. 2015 Dec 22; 112(51):E7148-54.
    View in: PubMed
    Score: 0.015
  10. Contribution of p53 to metastasis. Cancer Discov. 2014 Apr; 4(4):405-14.
    View in: PubMed
    Score: 0.013
  11. Forkhead box O1 (FOXO1) protein, but not p53, contributes to robust induction of p21 expression in fasted mice. J Biol Chem. 2013 Sep 27; 288(39):27999-8008.
    View in: PubMed
    Score: 0.013
  12. Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models. J Clin Invest. 2012 Apr; 122(4):1541-52.
    View in: PubMed
    Score: 0.011
  13. Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis. Mol Cell Biol. 2010 Nov; 30(21):5043-56.
    View in: PubMed
    Score: 0.010
  14. A Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignancies. Cancer Chemother Pharmacol. 2011 Jun; 67(6):1225-37.
    View in: PubMed
    Score: 0.010
  15. Response of small intestinal epithelial cells to acute disruption of cell division through CDC25 deletion. Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12):4701-6.
    View in: PubMed
    Score: 0.009
  16. Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5680-5.
    View in: PubMed
    Score: 0.008
  17. Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases. Mol Cell Biol. 2005 Apr; 25(7):2853-60.
    View in: PubMed
    Score: 0.007
  18. BRCA1-Mediated Dual Regulation of Ferroptosis Exposes a Vulnerability to GPX4 and PARP Co-Inhibition in BRCA1-Deficient Cancers. Cancer Discov. 2024 Aug 02; 14(8):1476-1495.
    View in: PubMed
    Score: 0.007
  19. Targeting chemotherapy resistance in mesenchymal triple-negative breast cancer: a phase II trial of neoadjuvant angiogenic and mTOR inhibition with chemotherapy. Invest New Drugs. 2023 Jun; 41(3):391-401.
    View in: PubMed
    Score: 0.006
  20. Reprogramming of H3K9bhb at regulatory elements is a key feature of fasting in the small intestine. Cell Rep. 2021 11 23; 37(8):110044.
    View in: PubMed
    Score: 0.006
  21. Metabolic stress induces GD2+ cancer stem cell-like phenotype in triple-negative breast cancer. Br J Cancer. 2022 03; 126(4):615-627.
    View in: PubMed
    Score: 0.006
  22. Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer. Nat Commun. 2021 09 10; 12(1):5389.
    View in: PubMed
    Score: 0.006
  23. Absence of apparent phenotype in mice lacking Cdc25C protein phosphatase. Mol Cell Biol. 2001 Jun; 21(12):3853-61.
    View in: PubMed
    Score: 0.005
  24. Immune system dysfunction and autoimmune disease in mice lacking Emk (Par-1) protein kinase. Mol Cell Biol. 2001 May; 21(9):3206-19.
    View in: PubMed
    Score: 0.005
  25. Anti-GD2 antibody dinutuximab inhibits triple-negative breast tumor growth by targeting GD2+ breast cancer stem-like cells. J Immunother Cancer. 2021 03; 9(3).
    View in: PubMed
    Score: 0.005
  26. A comprehensive overview of metaplastic breast cancer: clinical features and molecular aberrations. Breast Cancer Res. 2020 11 04; 22(1):121.
    View in: PubMed
    Score: 0.005
  27. The RNA-binding protein AKAP8 suppresses tumor metastasis by antagonizing EMT-associated alternative splicing. Nat Commun. 2020 01 24; 11(1):486.
    View in: PubMed
    Score: 0.005
  28. Neoadjuvant Talazoparib for Patients With Operable Breast Cancer With a Germline BRCA Pathogenic Variant. J Clin Oncol. 2020 02 10; 38(5):388-394.
    View in: PubMed
    Score: 0.005
  29. Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. Cell. 2019 08 22; 178(5):1115-1131.e15.
    View in: PubMed
    Score: 0.005
  30. 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers. Clin Cancer Res. 2019 09 15; 25(18):5702-5716.
    View in: PubMed
    Score: 0.005
  31. Sphingosine Kinase 1 Signaling Promotes Metastasis of Triple-Negative Breast Cancer. Cancer Res. 2019 08 15; 79(16):4211-4226.
    View in: PubMed
    Score: 0.005
  32. Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer. Cancer Res. 2019 05 01; 79(9):2327-2338.
    View in: PubMed
    Score: 0.005
  33. Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation. Sci Rep. 2019 02 13; 9(1):1949.
    View in: PubMed
    Score: 0.005
  34. Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1. Mol Cell. 2018 08 16; 71(4):606-620.e7.
    View in: PubMed
    Score: 0.004
  35. CHK1 Inhibition in Small-Cell Lung Cancer Produces Single-Agent Activity in Biomarker-Defined Disease Subsets and Combination Activity with Cisplatin or Olaparib. Cancer Res. 2017 07 15; 77(14):3870-3884.
    View in: PubMed
    Score: 0.004
  36. Patient-derived xenograft (PDX) models in basic and translational breast cancer research. Cancer Metastasis Rev. 2016 12; 35(4):547-573.
    View in: PubMed
    Score: 0.004
  37. Phosphorylation of serine 367 of FOXC2 by p38 regulates ZEB1 and breast cancer metastasis, without impacting primary tumor growth. Oncogene. 2016 11 17; 35(46):5977-5988.
    View in: PubMed
    Score: 0.004
  38. Type I interferons link viral infection to enhanced epithelial turnover and repair. Cell Host Microbe. 2015 Jan 14; 17(1):85-97.
    View in: PubMed
    Score: 0.003
  39. A phase II study of UCN-01 in combination with irinotecan in patients with metastatic triple negative breast cancer. Breast Cancer Res Treat. 2013 Jan; 137(2):483-92.
    View in: PubMed
    Score: 0.003
  40. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature. 2012 Jun 10; 486(7403):353-60.
    View in: PubMed
    Score: 0.003
  41. Fine-tuning p53 activity through C-terminal modification significantly contributes to HSC homeostasis and mouse radiosensitivity. Genes Dev. 2011 Jul 01; 25(13):1426-38.
    View in: PubMed
    Score: 0.003
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.