Connection

HELEN PIWNICA-WORMS to Staurosporine

This is a "connection" page, showing publications HELEN PIWNICA-WORMS has written about Staurosporine.
Connection Strength

0.635
  1. Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models. J Clin Invest. 2012 Apr; 122(4):1541-52.
    View in: PubMed
    Score: 0.412
  2. A Phase 1 study of UCN-01 in combination with irinotecan in patients with resistant solid tumor malignancies. Cancer Chemother Pharmacol. 2011 Jun; 67(6):1225-37.
    View in: PubMed
    Score: 0.092
  3. Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding. Oncogene. 2001 Apr 05; 20(15):1839-51.
    View in: PubMed
    Score: 0.048
  4. The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01. J Biol Chem. 2000 Feb 25; 275(8):5600-5.
    View in: PubMed
    Score: 0.045
  5. A phase II study of UCN-01 in combination with irinotecan in patients with metastatic triple negative breast cancer. Breast Cancer Res Treat. 2013 Jan; 137(2):483-92.
    View in: PubMed
    Score: 0.027
  6. UCN-01 abrogates G2 arrest through a Cdc2-dependent pathway that is associated with inactivation of the Wee1Hu kinase and activation of the Cdc25C phosphatase. J Biol Chem. 1998 Dec 11; 273(50):33455-64.
    View in: PubMed
    Score: 0.010
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.