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ANDREW GLADDEN

TitleAssistant Professor
InstitutionMD Anderson
DepartmentGenetics
Address6767 Bertner St
Houston TX 77030-2603
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Parrish ML, Broaddus RR, Gladden AB. Mechanisms of mutant ?-catenin in endometrial cancer progression. Front Oncol. 2022; 12:1009345. PMID: 36248967; PMCID: PMC9556987.
      Citations: 1     
    2. Krneta-Stankic V, Corkins ME, Paulucci-Holthauzen A, Kloc M, Gladden AB, Miller RK. The Wnt/PCP formin Daam1 drives cell-cell adhesion during nephron development. Cell Rep. 2021 07 06; 36(1):109340. PMID: 34233186; PMCID: PMC8629027.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    3. Corkins ME, Krneta-Stankic V, Kloc M, McCrea PD, Gladden AB, Miller RK. Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis. PLoS One. 2019; 14(8):e0221698. PMID: 31469868; PMCID: PMC6716777.
      Citations: 4     Fields:    Translation:AnimalsCells
    4. Lopez EW, Vue Z, Broaddus RR, Behringer RR, Gladden AB. The ERM family member Merlin is required for endometrial gland morphogenesis. Dev Biol. 2018 10 15; 442(2):301-314. PMID: 30118662.
      Citations: 4     Fields:    Translation:AnimalsCells
    5. Williams E, Villar-Prados A, Bowser J, Broaddus R, Gladden AB. Loss of polarity alters proliferation and differentiation in low-grade endometrial cancers by disrupting Notch signaling. PLoS One. 2017; 12(12):e0189081. PMID: 29206870; PMCID: PMC5716545.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    6. Timsah Z, Ahmed Z, Ivan C, Berrout J, Gagea M, Zhou Y, Pena GN, Hu X, Vallien C, Kingsley CV, Lu Y, Hancock JF, Liu J, Gladden AB, Mills GB, Lopez-Berestein G, Hung MC, Sood AK, Bogdanov M, Ladbury JE. Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer. Oncogene. 2016 04 28; 35(17):2186-96. PMID: 26212011; PMCID: PMC4792786.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    7. Yang CC, Graves HK, Moya IM, Tao C, Hamaratoglu F, Gladden AB, Halder G. Differential regulation of the Hippo pathway by adherens junctions and apical-basal cell polarity modules. Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6):1785-90. PMID: 25624491; PMCID: PMC4330745.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    8. Hebert AM, DuBoff B, Casaletto JB, Gladden AB, McClatchey AI. Merlin/ERM proteins establish cortical asymmetry and centrosome position. Genes Dev. 2012 Dec 15; 26(24):2709-23. PMID: 23249734; PMCID: PMC3533076.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    9. Longworth MS, Walker JA, Anderssen E, Moon NS, Gladden A, Heck MM, Ramaswamy S, Dyson NJ. A shared role for RBF1 and dCAP-D3 in the regulation of transcription with consequences for innate immunity. PLoS Genet. 2012; 8(4):e1002618. PMID: 22496667; PMCID: PMC3320600.
      Citations: 29     Fields:    Translation:AnimalsCells
    10. Gladden AB, Hebert AM, Schneeberger EE, McClatchey AI. The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex. Dev Cell. 2010 Nov 16; 19(5):727-39. PMID: 21074722; PMCID: PMC3033574.
      Citations: 92     Fields:    Translation:AnimalsCells
    11. Benhamouche S, Curto M, Saotome I, Gladden AB, Liu CH, Giovannini M, McClatchey AI. Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver. Genes Dev. 2010 Aug 15; 24(16):1718-30. PMID: 20675406; PMCID: PMC2922501.
      Citations: 137     Fields:    Translation:AnimalsCells
    12. Aggarwal P, Lessie MD, Lin DI, Pontano L, Gladden AB, Nuskey B, Goradia A, Wasik MA, Klein-Szanto AJ, Rustgi AK, Bassing CH, Diehl JA. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes Dev. 2007 Nov 15; 21(22):2908-22. PMID: 18006686; PMCID: PMC2049193.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    13. Lin DI, Lessie MD, Gladden AB, Bassing CH, Wagner KU, Diehl JA. Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis. Oncogene. 2008 Feb 21; 27(9):1231-42. PMID: 17724472; PMCID: PMC3733559.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    14. Marzec M, Kasprzycka M, Lai R, Gladden AB, Wlodarski P, Tomczak E, Nowell P, Deprimo SE, Sadis S, Eck S, Schuster SJ, Diehl JA, Wasik MA. Mantle cell lymphoma cells express predominantly cyclin D1a isoform and are highly sensitive to selective inhibition of CDK4 kinase activity. Blood. 2006 Sep 01; 108(5):1744-50. PMID: 16690963; PMCID: PMC1895502.
      Citations: 66     Fields:    Translation:HumansCells
    15. Gladden AB, Woolery R, Aggarwal P, Wasik MA, Diehl JA. Expression of constitutively nuclear cyclin D1 in murine lymphocytes induces B-cell lymphoma. Oncogene. 2006 Feb 16; 25(7):998-1007. PMID: 16247460; PMCID: PMC2832762.
      Citations: 66     Fields:    Translation:AnimalsCells
    16. Gladden AB, Diehl JA. Location, location, location: the role of cyclin D1 nuclear localization in cancer. J Cell Biochem. 2005 Dec 01; 96(5):906-13. PMID: 16163738.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    17. Petre-Draviam CE, Williams EB, Burd CJ, Gladden A, Moghadam H, Meller J, Diehl JA, Knudsen KE. A central domain of cyclin D1 mediates nuclear receptor corepressor activity. Oncogene. 2005 Jan 13; 24(3):431-44. PMID: 15558026.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    18. Lu F, Gladden AB, Diehl JA. An alternatively spliced cyclin D1 isoform, cyclin D1b, is a nuclear oncogene. Cancer Res. 2003 Nov 01; 63(21):7056-61. PMID: 14612495.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    19. Gladden AB, Diehl JA. Cell cycle progression without cyclin E/CDK2: breaking down the walls of dogma. Cancer Cell. 2003 Sep; 4(3):160-2. PMID: 14522248.
      Citations: 28     Fields:    Translation:AnimalsCells
    20. Gladden AB, Diehl JA. The cyclin D1-dependent kinase associates with the pre-replication complex and modulates RB.MCM7 binding. J Biol Chem. 2003 Mar 14; 278(11):9754-60. PMID: 12519773.
      Citations: 34     Fields:    Translation:AnimalsCells
    21. Alt JR, Gladden AB, Diehl JA. p21(Cip1) Promotes cyclin D1 nuclear accumulation via direct inhibition of nuclear export. J Biol Chem. 2002 Mar 08; 277(10):8517-23. PMID: 11751903.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    22. P09-20 LB. Ultra-deep sequencing of full-length HIV-1 genomes identifies rapid viral evolution during acute infection. Retrovirology. 6.
    23. Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer. Oncogene.
    24. Differential regulation of the Hippo pathway by adherens junctions and apical- Basal cell polarity modules. Proceedings of the National Academy of Sciences of the United States of America. 112:1785-1790.
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