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This is a "connection" page, showing publications co-authored by KEN HE YOUNG and ZIJUN XU-MONETTE.
KEN HE YOUNG
Connection Strength
12.207
ZIJUN XU-MONETTE
  1. DNA mismatch repair defect and intratumor heterogeneous deficiency differently impact immune responses in diffuse large B-cell lymphoma. Oncoimmunology. 2024; 13(1):2384667.
    View in: PubMed
    Score: 0.980
  2. Tumor-Infiltrating Normal B Cells Revealed by Immunoglobulin Repertoire Clonotype Analysis Are Highly Prognostic and Crucial for Antitumor Immune Responses in DLBCL. Clin Cancer Res. 2023 12 01; 29(23):4808-4821.
    View in: PubMed
    Score: 0.935
  3. Therapeutic vaccines for aggressive B-cell lymphoma. Leuk Lymphoma. 2020 12; 61(13):3038-3051.
    View in: PubMed
    Score: 0.746
  4. PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response? Front Immunol. 2017; 8:1597.
    View in: PubMed
    Score: 0.617
  5. PD-1 expression and clinical PD-1 blockade in B-cell lymphomas. Blood. 2018 01 04; 131(1):68-83.
    View in: PubMed
    Score: 0.614
  6. The TP53 tumor suppressor and autophagy in malignant lymphoma. Autophagy. 2012 May 01; 8(5):842-5.
    View in: PubMed
    Score: 0.417
  7. Dysfunction of the TP53 tumor suppressor gene in lymphoid malignancies. Blood. 2012 Apr 19; 119(16):3668-83.
    View in: PubMed
    Score: 0.411
  8. Flow cytometry quantification of tumor-infiltrating lymphocytes to predict the survival of patients with diffuse large B-cell lymphoma. Front Immunol. 2024; 15:1335689.
    View in: PubMed
    Score: 0.236
  9. Correction: Mechanisms of ferroptosis and targeted therapeutic approaches in lymphoma. Cell Death Dis. 2024 Jan 09; 15(1):19.
    View in: PubMed
    Score: 0.235
  10. Mechanisms of ferroptosis and targeted therapeutic approaches in lymphoma. Cell Death Dis. 2023 11 25; 14(11):771.
    View in: PubMed
    Score: 0.233
  11. The progress of novel strategies on immune-based therapy in relapsed or refractory diffuse large B-cell lymphoma. Exp Hematol Oncol. 2023 Aug 14; 12(1):72.
    View in: PubMed
    Score: 0.229
  12. EBV-positive DLBCL frequently harbors somatic mutations associated with clonal hematopoiesis of indeterminate potential. Blood Adv. 2023 04 11; 7(7):1308-1311.
    View in: PubMed
    Score: 0.224
  13. Metabolic Reprogramming and Potential Therapeutic Targets in Lymphoma. Int J Mol Sci. 2023 Mar 13; 24(6).
    View in: PubMed
    Score: 0.222
  14. Genetic Subtyping and Phenotypic Characterization of the Immune Microenvironment and MYC/BCL2 Double Expression Reveal Heterogeneity in Diffuse Large B-cell Lymphoma. Clin Cancer Res. 2022 Mar 01; 28(5):972-983.
    View in: PubMed
    Score: 0.207
  15. Molecular and genetic biomarkers implemented from next-generation sequencing provide treatment insights in clinical practice for Waldenstr?m macroglobulinemia. Neoplasia. 2021 04; 23(4):361-374.
    View in: PubMed
    Score: 0.194
  16. Predictive Model for Idiopathic Multicentric Castleman Disease Supporting Treatment Decisions. Oncologist. 2021 01; 26(1):4-6.
    View in: PubMed
    Score: 0.190
  17. A refined cell-of-origin classifier with targeted NGS and artificial intelligence shows robust predictive value in DLBCL. Blood Adv. 2020 07 28; 4(14):3391-3404.
    View in: PubMed
    Score: 0.185
  18. Immunoglobulin somatic hypermutation has clinical impact in DLBCL and potential implications for immune checkpoint blockade and neoantigen-based immunotherapies. J Immunother Cancer. 2019 10 22; 7(1):272.
    View in: PubMed
    Score: 0.176
  19. Dysregulation of Cell Survival in Diffuse Large B Cell Lymphoma: Mechanisms and Therapeutic Targets. Front Oncol. 2019; 9:107.
    View in: PubMed
    Score: 0.168
  20. Immune Profiling and Quantitative Analysis Decipher the Clinical Role of Immune-Checkpoint Expression in the Tumor Immune Microenvironment of DLBCL. Cancer Immunol Res. 2019 04; 7(4):644-657.
    View in: PubMed
    Score: 0.168
  21. Different prevalence and clinical outcome of Epstein-Barr virus positive diffuse large B-cell lymphoma between North American and non-Western populations. Ann Transl Med. 2018 Jun; 6(11):236.
    View in: PubMed
    Score: 0.160
  22. Primary Bone Lymphoma Exhibits a Favorable Prognosis and Distinct Gene Expression Signatures Resembling Diffuse Large B-Cell Lymphoma Derived From Centrocytes in the Germinal Center. Am J Surg Pathol. 2017 Oct; 41(10):1309-1321.
    View in: PubMed
    Score: 0.152
  23. Clinical and pathological characteristics of HIV- and HHV-8-negative Castleman disease. Blood. 2017 03 23; 129(12):1658-1668.
    View in: PubMed
    Score: 0.145
  24. Assessment of CD37 B-cell antigen and cell of origin significantly improves risk prediction in diffuse large B-cell lymphoma. Blood. 2016 12 29; 128(26):3083-3100.
    View in: PubMed
    Score: 0.143
  25. Immunophenotypic and diagnostic characterization of angioimmunoblastic T-cell lymphoma by advanced flow cytometric technology. Leuk Lymphoma. 2016 12; 57(12):2804-2812.
    View in: PubMed
    Score: 0.138
  26. Clinical and Biologic Significance of MYC Genetic Mutations in De Novo Diffuse Large B-cell Lymphoma. Clin Cancer Res. 2016 07 15; 22(14):3593-605.
    View in: PubMed
    Score: 0.137
  27. p63 expression confers significantly better survival outcomes in high-risk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function. Aging (Albany NY). 2016 Feb; 8(2):345-65.
    View in: PubMed
    Score: 0.136
  28. Clinicopathologic features and outcomes of lymphoplasmacytic lymphoma patients with monoclonal IgG or IgA paraprotein expression. Leuk Lymphoma. 2016 May; 57(5):1104-13.
    View in: PubMed
    Score: 0.135
  29. Clinical features, tumor biology, and prognosis associated with MYC rearrangement and Myc overexpression in diffuse large B-cell lymphoma patients treated with rituximab-CHOP. Mod Pathol. 2015 Dec; 28(12):1555-73.
    View in: PubMed
    Score: 0.134
  30. Crystal-storing histiocytosis: a clinicopathological study of 13 cases. Histopathology. 2016 Mar; 68(4):482-91.
    View in: PubMed
    Score: 0.132
  31. Waldenstr?m macroglobulinemia with extramedullary involvement at initial diagnosis portends a poorer prognosis. J Hematol Oncol. 2015 Jun 24; 8:74.
    View in: PubMed
    Score: 0.130
  32. Clinical and biological significance of de novo CD5+ diffuse large B-cell lymphoma in Western countries. Oncotarget. 2015 Mar 20; 6(8):5615-33.
    View in: PubMed
    Score: 0.128
  33. Epstein-Barr virus-positive nodular lymphocyte predominant Hodgkin lymphoma. Ann Diagn Pathol. 2014 Aug; 18(4):203-9.
    View in: PubMed
    Score: 0.120
  34. Clonally related composite follicular lymphoma and mantle cell lymphoma with clinicopathologic features and biological implications. Hum Pathol. 2013 Dec; 44(12):2658-67.
    View in: PubMed
    Score: 0.115
  35. MDM2 phenotypic and genotypic profiling, respective to TP53 genetic status, in diffuse large B-cell lymphoma patients treated with rituximab-CHOP immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program. Blood. 2013 Oct 10; 122(15):2630-40.
    View in: PubMed
    Score: 0.115
  36. Mutational profile and prognostic significance of TP53 in diffuse large B-cell lymphoma patients treated with R-CHOP: report from an International DLBCL Rituximab-CHOP Consortium Program Study. Blood. 2012 Nov 08; 120(19):3986-96.
    View in: PubMed
    Score: 0.107
  37. Composite mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma: a clinicopathologic and molecular study. Hum Pathol. 2013 Jan; 44(1):110-21.
    View in: PubMed
    Score: 0.107
  38. Immunohistochemical double-hit score is a strong predictor of outcome in patients with diffuse large B-cell lymphoma treated with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone. J Clin Oncol. 2012 Oct 01; 30(28):3460-7.
    View in: PubMed
    Score: 0.105
  39. Molecular characteristics of mantle cell lymphoma presenting with clonal plasma cell component. Am J Surg Pathol. 2011 Feb; 35(2):177-89.
    View in: PubMed
    Score: 0.096
  40. Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma. Leukemia. 2023 10; 37(10):2094-2106.
    View in: PubMed
    Score: 0.057
  41. ETS1 phosphorylation at threonine 38 is associated with the cell of origin of diffuse large B cell lymphoma and sustains the growth of tumour cells. Br J Haematol. 2023 Oct; 203(2):244-254.
    View in: PubMed
    Score: 0.057
  42. Clinical relevance of MYC/BCL2 expression and cell of origin in patients with diffuse large b-cell lymphoma treated with autologous transplant. Bone Marrow Transplant. 2023 09; 58(9):1000-1007.
    View in: PubMed
    Score: 0.056
  43. Targetable vulnerability of deregulated FOXM1/PLK1 signaling axis in diffuse large B cell lymphoma. Am J Cancer Res. 2022; 12(10):4666-4679.
    View in: PubMed
    Score: 0.054
  44. Clinical characteristics and outcomes of Castleman disease: a multicenter Consortium study of 428 patients with 15-year follow-up. Am J Cancer Res. 2022; 12(9):4227-4240.
    View in: PubMed
    Score: 0.054
  45. Analysis of albumin as a prognostic factor in HHV-8/HIV-negative Castleman disease from a multicenter study. Leuk Lymphoma. 2022 12; 63(13):3082-3091.
    View in: PubMed
    Score: 0.054
  46. IRF8 is a transcriptional activator of CD37 expression in diffuse large B-cell lymphoma. Blood Adv. 2022 04 12; 6(7):2254-2266.
    View in: PubMed
    Score: 0.052
  47. Determining clinical course of diffuse large B-cell lymphoma using targeted transcriptome and machine learning algorithms. Blood Cancer J. 2022 02 01; 12(2):25.
    View in: PubMed
    Score: 0.051
  48. EBV+ high-grade B cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements: a multi-institutional study. Histopathology. 2022 Feb; 80(3):575-588.
    View in: PubMed
    Score: 0.051
  49. Transducin ?-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma. Haematologica. 2021 11 01; 106(11):2927-2939.
    View in: PubMed
    Score: 0.051
  50. A composite single-nucleotide polymorphism prediction signature for extranodal natural killer/T-cell lymphoma. Blood. 2021 08 12; 138(6):452-463.
    View in: PubMed
    Score: 0.050
  51. Genomic complexity is associated with epigenetic regulator mutations and poor prognosis in diffuse large B-cell lymphoma. Oncoimmunology. 2021; 10(1):1928365.
    View in: PubMed
    Score: 0.050
  52. MYD88 L265P elicits mutation-specific ubiquitination to drive NF-?B activation and lymphomagenesis. Blood. 2021 03 25; 137(12):1615-1627.
    View in: PubMed
    Score: 0.049
  53. Aggressive B-cell Lymphoma with MYC/TP53 Dual Alterations Displays Distinct Clinicopathobiological Features and Response to Novel Targeted Agents. Mol Cancer Res. 2021 02; 19(2):249-260.
    View in: PubMed
    Score: 0.047
  54. XPO1 expression worsens the prognosis of unfavorable DLBCL that can be effectively targeted by selinexor in the absence of mutant p53. J Hematol Oncol. 2020 11 04; 13(1):148.
    View in: PubMed
    Score: 0.047
  55. A Novel Predictive Model for Idiopathic Multicentric Castleman Disease: The International Castleman Disease Consortium Study. Oncologist. 2020 11; 25(11):963-973.
    View in: PubMed
    Score: 0.047
  56. Preclinical evaluation of a regimen combining chidamide and ABT-199 in acute myeloid leukemia. Cell Death Dis. 2020 09 18; 11(9):778.
    View in: PubMed
    Score: 0.047
  57. Targeting PD-L1 in non-small cell lung cancer using CAR T cells. Oncogenesis. 2020 Aug 13; 9(8):72.
    View in: PubMed
    Score: 0.046
  58. Prognostic factors, therapeutic approaches, and distinct immunobiologic features in patients with primary mediastinal large B-cell lymphoma on long-term follow-up. Blood Cancer J. 2020 05 04; 10(5):49.
    View in: PubMed
    Score: 0.046
  59. Ubiquitination of the DNA-damage checkpoint kinase CHK1 by TRAF4 is required for CHK1 activation. J Hematol Oncol. 2020 05 01; 13(1):40.
    View in: PubMed
    Score: 0.046
  60. LAG3: a novel immune checkpoint expressed by multiple lymphocyte subsets in diffuse large B-cell lymphoma. Blood Adv. 2020 04 14; 4(7):1367-1377.
    View in: PubMed
    Score: 0.045
  61. Uncovering the Role of RNA-Binding Protein hnRNP K in B-Cell Lymphomas. J Natl Cancer Inst. 2020 01 01; 112(1):95-106.
    View in: PubMed
    Score: 0.045
  62. Tissue-specific microRNA expression alters cancer susceptibility conferred by a TP53 noncoding variant. Nat Commun. 2019 11 07; 10(1):5061.
    View in: PubMed
    Score: 0.044
  63. Glyphosate induces benign monoclonal gammopathy and promotes multiple myeloma progression in mice. J Hematol Oncol. 2019 07 05; 12(1):70.
    View in: PubMed
    Score: 0.043
  64. PD-1/PD-L1 expression and interaction by automated quantitative immunofluorescent analysis show adverse prognostic impact in patients with diffuse large B-cell lymphoma having T-cell infiltration: a study from the International DLBCL Consortium Program. Mod Pathol. 2019 06; 32(6):741-754.
    View in: PubMed
    Score: 0.042
  65. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces peripheral blood abnormalities and plasma cell neoplasms resembling multiple myeloma in mice. Cancer Lett. 2019 01; 440-441:135-144.
    View in: PubMed
    Score: 0.041
  66. B-cell receptor-mediated NFATc1 activation induces IL-10/STAT3/PD-L1 signaling in diffuse large B-cell lymphoma. Blood. 2018 10 25; 132(17):1805-1817.
    View in: PubMed
    Score: 0.041
  67. Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma. Neoplasia. 2018 06; 20(6):574-593.
    View in: PubMed
    Score: 0.040
  68. Richter transformation driven by Epstein-Barr virus reactivation during therapy-related immunosuppression in chronic lymphocytic leukaemia. J Pathol. 2018 05; 245(1):61-73.
    View in: PubMed
    Score: 0.039
  69. Hepatitis C virus positive diffuse large B-cell lymphomas have distinct molecular features and lack BCL2 translocations. Br J Cancer. 2017 Nov 21; 117(11):1685-1688.
    View in: PubMed
    Score: 0.038
  70. AKT Hyperactivation and the Potential of AKT-Targeted Therapy in Diffuse Large B-Cell Lymphoma. Am J Pathol. 2017 Aug; 187(8):1700-1716.
    View in: PubMed
    Score: 0.037
  71. NF-?B p50 activation associated with immune dysregulation confers poorer survival for diffuse large B-cell lymphoma patients with wild-type p53. Mod Pathol. 2017 06; 30(6):854-876.
    View in: PubMed
    Score: 0.037
  72. RelA NF-?B subunit activation as a therapeutic target in diffuse large B-cell lymphoma. Aging (Albany NY). 2016 12 08; 8(12):3321-3340.
    View in: PubMed
    Score: 0.036
  73. Targeting the hexosamine biosynthetic pathway and O-linked N-acetylglucosamine cycling for therapeutic and imaging capabilities in diffuse large B-cell lymphoma. Oncotarget. 2016 Dec 06; 7(49):80599-80611.
    View in: PubMed
    Score: 0.036
  74. Stratifying diffuse large B-cell lymphoma patients treated with chemoimmunotherapy: GCB/non-GCB by immunohistochemistry is still a robust and feasible marker. Oncotarget. 2016 Apr 05; 7(14):18036-49.
    View in: PubMed
    Score: 0.034
  75. Prognostic impact of concurrent MYC and BCL6 rearrangements and expression in de novo diffuse large B-cell lymphoma. Oncotarget. 2016 Jan 19; 7(3):2401-16.
    View in: PubMed
    Score: 0.034
  76. Tetraspanin CD37 protects against the development of B cell lymphoma. J Clin Invest. 2016 Feb; 126(2):653-66.
    View in: PubMed
    Score: 0.034
  77. Prognostic impact of c-Rel nuclear expression and REL amplification and crosstalk between c-Rel and the p53 pathway in diffuse large B-cell lymphoma. Oncotarget. 2015 Sep 15; 6(27):23157-80.
    View in: PubMed
    Score: 0.033
  78. Prognostic and biological significance of survivin expression in patients with diffuse large B-cell lymphoma treated with rituximab-CHOP therapy. Mod Pathol. 2015 Oct; 28(10):1297-314.
    View in: PubMed
    Score: 0.033
  79. Evaluation of NF-?B subunit expression and signaling pathway activation demonstrates that p52 expression confers better outcome in germinal center B-cell-like diffuse large B-cell lymphoma in association with CD30 and BCL2 functions. Mod Pathol. 2015 Sep; 28(9):1202-13.
    View in: PubMed
    Score: 0.033
  80. Age cutoff for Epstein-Barr virus-positive diffuse large B-cell lymphoma--is it necessary? Oncotarget. 2015 Jun 10; 6(16):13933-45.
    View in: PubMed
    Score: 0.032
  81. The oncogenic microRNA miR-21 promotes regulated necrosis in mice. Nat Commun. 2015 May 20; 6:7151.
    View in: PubMed
    Score: 0.032
  82. Predicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models. BMC Cancer. 2015 Apr 08; 15:235.
    View in: PubMed
    Score: 0.032
  83. Diffuse large B-cell lymphoma classification system that associates normal B-cell subset phenotypes with prognosis. J Clin Oncol. 2015 Apr 20; 33(12):1379-88.
    View in: PubMed
    Score: 0.032
  84. Dysregulated CXCR4 expression promotes lymphoma cell survival and independently predicts disease progression in germinal center B-cell-like diffuse large B-cell lymphoma. Oncotarget. 2015 Mar 20; 6(8):5597-614.
    View in: PubMed
    Score: 0.032
  85. LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers. Nat Commun. 2014 Oct 17; 5:5218.
    View in: PubMed
    Score: 0.031
  86. Clinical implications of phosphorylated STAT3 expression in De Novo diffuse large B-cell lymphoma. Clin Cancer Res. 2014 Oct 01; 20(19):5113-23.
    View in: PubMed
    Score: 0.031
  87. Regulation of p53-targeting microRNAs by polycyclic aromatic hydrocarbons: Implications in the etiology of multiple myeloma. Mol Carcinog. 2015 Oct; 54(10):1060-9.
    View in: PubMed
    Score: 0.030
  88. Prevalence and clinical implications of cyclin D1 expression in diffuse large B-cell lymphoma (DLBCL) treated with immunochemotherapy: a report from the International DLBCL Rituximab-CHOP Consortium Program. Cancer. 2014 Jun 15; 120(12):1818-29.
    View in: PubMed
    Score: 0.030
  89. Prevalence and clinical implications of epstein-barr virus infection in de novo diffuse large B-cell lymphoma in Western countries. Clin Cancer Res. 2014 May 01; 20(9):2338-49.
    View in: PubMed
    Score: 0.030
  90. Rearrangements of MYC gene facilitate risk stratification in diffuse large B-cell lymphoma patients treated with rituximab-CHOP. Mod Pathol. 2014 Jul; 27(7):958-71.
    View in: PubMed
    Score: 0.029
  91. Breast implant-associated anaplastic large-cell lymphoma: long-term follow-up of 60 patients. J Clin Oncol. 2014 Jan 10; 32(2):114-20.
    View in: PubMed
    Score: 0.029
  92. Imbalanced matriptase pericellular proteolysis contributes to the pathogenesis of malignant B-cell lymphomas. Am J Pathol. 2013 Oct; 183(4):1306-17.
    View in: PubMed
    Score: 0.029
  93. Single nucleotide variation in the TP53 3' untranslated region in diffuse large B-cell lymphoma treated with rituximab-CHOP: a report from the International DLBCL Rituximab-CHOP Consortium Program. Blood. 2013 May 30; 121(22):4529-40.
    View in: PubMed
    Score: 0.028
  94. MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program. Blood. 2013 May 16; 121(20):4021-31; quiz 4250.
    View in: PubMed
    Score: 0.028
  95. CD30 expression defines a novel subgroup of diffuse large B-cell lymphoma with favorable prognosis and distinct gene expression signature: a report from the International DLBCL Rituximab-CHOP Consortium Program Study. Blood. 2013 Apr 04; 121(14):2715-24.
    View in: PubMed
    Score: 0.028
  96. Patients with diffuse large B-cell lymphoma of germinal center origin with BCL2 translocations have poor outcome, irrespective of MYC status: a report from an International DLBCL rituximab-CHOP Consortium Program Study. Haematologica. 2013 Feb; 98(2):255-63.
    View in: PubMed
    Score: 0.027
  97. High levels of nuclear MYC protein predict the presence of MYC rearrangement in diffuse large B-cell lymphoma. Am J Surg Pathol. 2012 Apr; 36(4):612-9.
    View in: PubMed
    Score: 0.026
  98. miRNA expression in diffuse large B-cell lymphoma treated with chemoimmunotherapy. Blood. 2011 Jul 28; 118(4):1034-40.
    View in: PubMed
    Score: 0.025
  99. The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation. Blood. 2011 Mar 24; 117(12):3391-401.
    View in: PubMed
    Score: 0.024
  100. A variant of the LRP4 gene affects the risk of chronic lymphocytic leukaemia transformation to Richter syndrome. Br J Haematol. 2011 Feb; 152(3):284-94.
    View in: PubMed
    Score: 0.024
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