STEPHEN YENZENLAISTEPHEN YENZEN LAI9565LAI, STEPHEN YENZENAssociate Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson25303977Pickering CR, Zhou JH, Lee JJ, Drummond JA, Peng SA, Saade RE, Tsai KY, Curry JL, Tetzlaff MT, Lai SY, Yu J, Muzny DM, Doddapaneni H, Shinbrot E, Covington KR, Zhang J, Seth S, Caulin C, Clayman GL, El-Naggar AK, Gibbs RA, Weber RS, Myers JN, Wheeler DA, Frederick MJClinical cancer research : an official journal of the American Association for Cancer ResearchMutational landscape of aggressive cutaneous squamous cell carcinoma. Clin Cancer Res. 2014 Dec 15; 20(24):6582-92.Clin Cancer Res2014-10-10T00:00:002014Mutational landscape of aggressive cutaneous squamous cell carcinoma.22770899Adachi M, Cui C, Dodge CT, Bhayani MK, Lai SYOral oncologyTargeting STAT3 inhibits growth and enhances radiosensitivity in head and neck squamous cell carcinoma. Oral Oncol. 2012 Dec; 48(12):1220-6.Oral Oncol2012-07-06T00:00:002012Targeting STAT3 inhibits growth and enhances radiosensitivity in head and neck squamous cell carcinoma.25427145Henderson YC, Ahn SH, Ryu J, Chen Y, Williams MD, El-Naggar AK, Gagea M, Schweppe RE, Haugen BR, Lai SY, Clayman GLThe Journal of clinical endocrinology and metabolismDevelopment and characterization of six new human papillary thyroid carcinoma cell lines. J Clin Endocrinol Metab. 2015 Feb; 100(2):E243-52.J Clin Endocrinol Metab2014-11-26T00:00:002014Development and characterization of six new human papillary thyroid carcinoma cell lines.1400 Pressler StHouston77030-4008TXAuthorship 1663002Authorship 1699282Authorship 1715541Authorship 1720202Authorship 1748741Authorship 1752331Authorship 17703112Authorship 1798917Authorship 1805753Authorship 1808042Authorship 1839591Authorship 1868213Authorship 1869637Authorship 1870244Authorship 18727614Authorship 1882539Authorship 1893583Authorship 1897459Authorship 1904612Authorship 19221515Authorship 1926065Authorship 1947264Authorship 1947684Authorship 1952282Authorship 195823815091212Cohen NA, Lai SY, Ziober AF, Ziober BLThe LaryngoscopeDysregulation of hypoxia inducible factor-1alpha in head and neck squamous cell carcinoma cell lines correlates with invasive potential. Laryngoscope. 2004 Mar; 114(3):418-23.Laryngoscope2004-03-01T00:00:002004Dysregulation of hypoxia inducible factor-1alpha in head and neck squamous cell carcinoma cell lines correlates with invasive potential.15381605Gadiparthi S, Lai SY, Branstetter BF, Ferris RLArchives of otolaryngology--head & neck surgeryRadiology quiz case 2. Parapharyngeal second branchial cleft cyst. Arch Otolaryngol Head Neck Surg. 2004 Sep; 130(9):1121, 1124-5.Arch Otolaryngol Head Neck Surg2004-09-01T00:00:002004Radiology quiz case 2. Parapharyngeal second branchial cleft cyst.15856028Lai SY, Childs EE, Xi S, Coppelli FM, Gooding WE, Wells A, Ferris RL, Grandis JROncogeneErythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma. Oncogene. 2005 Jun 23; 24(27):4442-9.Oncogene2005-06-23T00:00:002005Erythropoietin-mediated activation of JAK-STAT signaling contributes to cellular invasion in head and neck squamous cell carcinoma.18720358Nance MA, Seethala RR, Wang Y, Chiosea SI, Myers EN, Johnson JT, Lai SYCancerTreatment and survival outcomes based on histologic grading in patients with head and neck mucoepidermoid carcinoma. Cancer. 2008 Oct 15; 113(8):2082-9.Cancer2008-10-15T00:00:002008Treatment and survival outcomes based on histologic grading in patients with head and neck mucoepidermoid carcinoma.19405086Cano ER, Lai SY, Caylakli F, Johnson JT, Ferris RL, Carrau RL, Snyderman CH, Gooding WE, Simenthal AA, Myers ENHead & neckManagement of squamous cell carcinoma of the base of tongue with chemoradiation and brachytherapy. Head Neck. 2009 Nov; 31(11):1431-8.Head Neck2009-11-01T00:00:002009Management of squamous cell carcinoma of the base of tongue with chemoradiation and brachytherapy.20471303Lai SY, Johnson FMDrug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapyDefining the role of the JAK-STAT pathway in head and neck and thoracic malignancies: implications for future therapeutic approaches. Drug Resist Updat. 2010 Jun; 13(3):67-78.Drug Resist Updat2010-05-14T00:00:002010Defining the role of the JAK-STAT pathway in head and neck and thoracic malignancies: implications for future therapeutic approaches.21868535Murata S, Adachi M, Kioi M, Torigoe S, Ijichi K, Hasegawa Y, Ogawa T, Bhayani MK, Lai SY, Mitsudo K, Tohnai IAnticancer researchEtodolac improves 5-FU sensitivity of head and neck cancer cells through inhibition of thymidylate synthase. Anticancer Res. 2011 Sep; 31(9):2893-8.Anticancer Res2011-09-01T00:00:002011Etodolac improves 5-FU sensitivity of head and neck cancer cells through inhibition of thymidylate synthase.22085809Bhayani MK, Calin GA, Lai SYMutation researchFunctional relevance of miRNA sequences in human disease. Mutat Res. 2012 Mar 01; 731(1-2):14-9.Mutat Res2011-11-06T00:00:002011Functional relevance of miRNA sequences in human disease.Endocrine Neoplasia & HDHead & Neck SurgeryRadiation OncologyMD AndersonADEL KEL-NAGGARADEL K EL-NAGGAR8614EL-NAGGAR, ADEL KProfessorJEFFREY NMYERSJEFFREY N MYERS8712MYERS, JEFFREY NProfessorDAVIDROSENTHALDAVID ROSENTHAL9001ROSENTHAL, DAVIDProfessorKATHERINE AHUTCHESONKATHERINE A HUTCHESON9161HUTCHESON, KATHERINE AAssociate Professor5.487090.00340216766research areas7.3340.0252592213coauthor of183.71741.445560similar to11292selected publicationsERICH MSTURGISERICH M STURGIS8744STURGIS, ERICH MProfessorCLIFTONFULLERCLIFTON FULLER9750FULLER, CLIFTONAssistant ProfessorMARIA ECABANILLASMARIA E CABANILLAS8975CABANILLAS, MARIA EAssociate ProfessorADAM SGARDENADAM S GARDEN8442GARDEN, ADAM SProfessorAuthorship 2141022Authorship 2145331Authorship 2150262Authorship 2157134Authorship 2169394Authorship 2184351Authorship 2190762Authorship 2204361Authorship 2253695Authorship 22749613Authorship 2275504Authorship 2288192Authorship 2298802Authorship 2302672Authorship 2317687Authorship 2322017Authorship 2331926Authorship 2333622Authorship 23458527543676Gaffen SL, Lai SY, Xu W, Gouilleux F, Groner B, Goldsmith MA, Greene WCProceedings of the National Academy of Sciences of the United States of AmericaSignaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity. Proc Natl Acad Sci U S A. 1995 Aug 01; 92(16):7192-6.Proc Natl Acad Sci U S A1995-08-01T00:00:001995Signaling through the interleukin 2 receptor beta chain activates a STAT-5-like DNA-binding activity.7545674Liu KD, Lai SY, Goldsmith MA, Greene WCThe Journal of biological chemistryIdentification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction. J Biol Chem. 1995 Sep 22; 270(38):22176-81.J Biol Chem1995-09-22T00:00:001995Identification of a variable region within the cytoplasmic tail of the IL-2 receptor beta chain that is required for growth signal transduction.8552611Lai SY, Xu W, Gaffen SL, Liu KD, Longmore GD, Greene WC, Goldsmith MAProceedings of the National Academy of Sciences of the United States of AmericaThe molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes. Proc Natl Acad Sci U S A. 1996 Jan 09; 93(1):231-5.Proc Natl Acad Sci U S A1996-01-09T00:00:001996The molecular role of the common gamma c subunit in signal transduction reveals functional asymmetry within multimeric cytokine receptor complexes.9535918Bauer JH, Liu KD, You Y, Lai SY, Goldsmith MAThe Journal of biological chemistryHeteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and prevention of apoptosis. J Biol Chem. 1998 Apr 10; 273(15):9255-60.J Biol Chem1998-04-10T00:00:001998Heteromerization of the gammac chain with the interleukin-9 receptor alpha subunit leads to STAT activation and prevention of apoptosis.10026152Watowich SS, Liu KD, Xie X, Lai SY, Mikami A, Longmore GD, Goldsmith MAThe Journal of biological chemistryOligomerization and scaffolding functions of the erythropoietin receptor cytoplasmic tail. J Biol Chem. 1999 Feb 26; 274(9):5415-21.J Biol Chem1999-02-26T00:00:001999Oligomerization and scaffolding functions of the erythropoietin receptor cytoplasmic tail.11107684Lai S, Kelleher K, Sataloff RTEar, nose, & throat journalVocal fold granuloma: the "ball-valve" phenomenon. Ear Nose Throat J. 2000 Nov; 79(11):836.Ear Nose Throat J2000-11-01T00:00:002000Vocal fold granuloma: the "ball-valve" phenomenon.11694678Shah SS, Lai SY, Ruchelli E, Kazahaya K, Mahboubi SPediatricsRetropharyngeal aberrant thymus. Pediatrics. 2001 Nov; 108(5):E94.Pediatrics2001-11-01T00:00:002001Retropharyngeal aberrant thymus.12160294Lai SY, Deffenderfer OF, Hanson W, Phillips MP, Thaler ERThe LaryngoscopeIdentification of upper respiratory bacterial pathogens with the electronic nose. Laryngoscope. 2002 Jun; 112(6):975-9.Laryngoscope2002-06-01T00:00:002002Identification of upper respiratory bacterial pathogens with the electronic nose.17921898Nayak JV, Walvekar RR, Andrade RS, Daamen N, Lai SY, Argiris A, Smith RP, Heron DE, Ferris RL, Johnson JT, Branstetter BFThe LaryngoscopeDeferring planned neck dissection following chemoradiation for stage IV head and neck cancer: the utility of PET-CT. Laryngoscope. 2007 Dec; 117(12):2129-34.Laryngoscope2007-12-01T00:00:002007Deferring planned neck dissection following chemoradiation for stage IV head and neck cancer: the utility of PET-CT.19464819Heron DE, Ferris RL, Karamouzis M, Andrade RS, Deeb EL, Burton S, Gooding WE, Branstetter BF, Mountz JM, Johnson JT, Argiris A, Grandis JR, Lai SYInternational journal of radiation oncology, biology, physicsStereotactic body radiotherapy for recurrent squamous cell carcinoma of the head and neck: results of a phase I dose-escalation trial. Int J Radiat Oncol Biol Phys. 2009 Dec 01; 75(5):1493-500.Int J Radiat Oncol Biol Phys2009-05-21T00:00:002009Stereotactic body radiotherapy for recurrent squamous cell carcinoma of the head and neck: results of a phase I dose-escalation trial.20030819Ward BK, Seethala RR, Barnes EL, Lai SYHead & neck oncologyBasal cell adenocarcinoma of a hard palate minor salivary gland: case report and review of the literature. Head Neck Oncol. 2009 Dec 23; 1:41.Head Neck Oncol2009-12-23T00:00:002009Basal cell adenocarcinoma of a hard palate minor salivary gland: case report and review of the literature.20133969Epperly MW, Lai SY, Kanai AJ, Mason N, Lopresi B, Dixon T, Franicola D, Niu Y, Wilson WR, Greenberger JSIn vivo (Athens, Greece)Effectiveness of combined modality radiotherapy of orthotopic human squamous cell carcinomas in Nu/Nu mice using cetuximab, tirapazamine and MnSOD-plasmid liposome gene therapy. In Vivo. 2010 Jan-Feb; 24(1):1-8.In Vivo2010-01-01T00:00:002010Effectiveness of combined modality radiotherapy of orthotopic human squamous cell carcinomas in Nu/Nu mice using cetuximab, tirapazamine and MnSOD-plasmid liposome gene therapy.20862661Ragan DK, Lai SY, Bankson JANMR in biomedicineFast, reproducible measurement of the vascular input function in mice using constrained reconstruction and cardiac sampling. NMR Biomed. 2011 May; 24(4):373-84.NMR Biomed2010-09-22T00:00:002010Fast, reproducible measurement of the vascular input function in mice using constrained reconstruction and cardiac sampling.21284048Feinstein TM, Lai SY, Lenzner D, Gooding W, Ferris RL, Grandis JR, Myers EN, Johnson JT, Heron DE, Argiris AHead & neckPrognostic factors in patients with high-risk locally advanced salivary gland cancers treated with surgery and postoperative radiotherapy. Head Neck. 2011 Mar; 33(3):318-23.Head Neck2011-01-31T00:00:002011Prognostic factors in patients with high-risk locally advanced salivary gland cancers treated with surgery and postoperative radiotherapy.21953943Adachi M, Mitsudo K, Yamamoto N, Hagiwara S, Shigetomi T, Fujimoto Y, Lai SY, Tohnai IHead & neckChemoradiotherapy for maxillary sinus adenoid cystic carcinoma using superselective intra-arterial infusion via a superficial temporal artery. Head Neck. 2013 Mar; 35(3):E89-93.Head Neck2011-09-26T00:00:002011Chemoradiotherapy for maxillary sinus adenoid cystic carcinoma using superselective intra-arterial infusion via a superficial temporal artery.22887122Ramirez MS, Lai SY, Bankson JANMR in biomedicineA throughput-optimized array system for multiple-mouse MRI. NMR Biomed. 2013 Mar; 26(3):237-47.NMR Biomed2012-08-10T00:00:002012A throughput-optimized array system for multiple-mouse MRI.23322563Bhayani MK, Hutcheson KA, Barringer DA, Lisec A, Alvarez CP, Roberts DB, Lai SY, Lewin JSHead & neckGastrostomy tube placement in patients with oropharyngeal carcinoma treated with radiotherapy or chemoradiotherapy: factors affecting placement and dependence. Head Neck. 2013 Nov; 35(11):1634-40.Head Neck2013-01-16T00:00:002013Gastrostomy tube placement in patients with oropharyngeal carcinoma treated with radiotherapy or chemoradiotherapy: factors affecting placement and dependence.24051544Hutcheson KA, Bhayani MK, Beadle BM, Gold KA, Shinn EH, Lai SY, Lewin JJAMA otolaryngology-- head & neck surgeryEat and exercise during radiotherapy or chemoradiotherapy for pharyngeal cancers: use it or lose it. JAMA Otolaryngol Head Neck Surg. 2013 Nov; 139(11):1127-34.JAMA Otolaryngol Head Neck Surg2013-11-01T00:00:002013Eat and exercise during radiotherapy or chemoradiotherapy for pharyngeal cancers: use it or lose it.24633882Monroe MM, Lai SYCurrent oncology reportsSentinel lymph node biopsy for oral cancer: supporting evidence and recent novel developments. Curr Oncol Rep. 2014 May; 16(5):385.Curr Oncol Rep2014-05-01T00:00:002014Sentinel lymph node biopsy for oral cancer: supporting evidence and recent novel developments.25913249Zhou M, Chen Y, Adachi M, Wen X, Erwin B, Mawlawi O, Lai SY, Li CBiomaterialsSingle agent nanoparticle for radiotherapy and radio-photothermal therapy in anaplastic thyroid cancer. Biomaterials. 2015 Jul; 57:41-9.Biomaterials2015-04-24T00:00:002015Single agent nanoparticle for radiotherapy and radio-photothermal therapy in anaplastic thyroid cancer.Authorship 2388452Authorship 2390412Authorship 2397161Authorship 2406451Authorship 2407026Authorship 2412922Authorship 2450602Authorship 2469204Authorship 2480731Authorship 2481147Authorship 2492778Authorship 2507835Authorship 2509271Authorship 2514333Authorship 2547776Authorship 2553644Authorship 25574619Authorship 2558446Authorship 25604210Authorship 2584477Authorship 2589332Authorship 2599163Authorship 260222127665592Goldsmith MA, Lai SY, Xu W, Amaral MC, Kuczek ES, Parent LJ, Mills GB, Tarr KL, Longmore GD, Greene WCThe Journal of biological chemistryGrowth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain. J Biol Chem. 1995 Sep 15; 270(37):21729-37.J Biol Chem1995-09-15T00:00:001995Growth signal transduction by the human interleukin-2 receptor requires cytoplasmic tyrosines of the beta chain and non-tyrosine residues of the gamma c chain.8702919Gaffen SL, Lai SY, Ha M, Liu X, Hennighausen L, Greene WC, Goldsmith MAThe Journal of biological chemistryDistinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity. J Biol Chem. 1996 Aug 30; 271(35):21381-90.J Biol Chem1996-08-30T00:00:001996Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity.8887542Lai SY, Molden J, Liu KD, Puck JM, White MD, Goldsmith MAThe EMBO journalInterleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor alpha subunit. EMBO J. 1996 Sep 02; 15(17):4506-14.EMBO J1996-09-02T00:00:001996Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor alpha subunit.9005984Lai SY, Molden J, Goldsmith MAThe Journal of clinical investigationShared gamma(c) subunit within the human interleukin-7 receptor complex. A molecular basis for the pathogenesis of X-linked severe combined immunodeficiency. J Clin Invest. 1997 Jan 15; 99(2):169-77.J Clin Invest1997-01-15T00:00:001997Shared gamma(c) subunit within the human interleukin-7 receptor complex. A molecular basis for the pathogenesis of X-linked severe combined immunodeficiency.9446647Longmore GD, You Y, Molden J, Liu KD, Mikami A, Lai SY, Pharr P, Goldsmith MABloodRedundant and selective roles for erythropoietin receptor tyrosines in erythropoiesis in vivo. Blood. 1998 Feb 01; 91(3):870-8.Blood1998-02-01T00:00:001998Redundant and selective roles for erythropoietin receptor tyrosines in erythropoiesis in vivo.10381500Gaffen SL, Lai SY, Longmore GD, Liu KD, Goldsmith MABloodGenetic evidence for an additional factor required for erythropoietin-induced signal transduction. Blood. 1999 Jul 01; 94(1):74-86.Blood1999-07-01T00:00:001999Genetic evidence for an additional factor required for erythropoietin-induced signal transduction.12160263Wolfe SG, Lai SY, Bigelow DCThe LaryngoscopeBilateral squamous cell carcinoma of the external auditory canals. Laryngoscope. 2002 Jun; 112(6):1003-5.Laryngoscope2002-06-01T00:00:002002Bilateral squamous cell carcinoma of the external auditory canals.15967106Mohyeldin A, Lu H, Dalgard C, Lai SY, Cohen N, Acs G, Verma ANeoplasia (New York, N.Y.)Erythropoietin signaling promotes invasiveness of human head and neck squamous cell carcinoma. Neoplasia. 2005 May; 7(5):537-43.Neoplasia2005-05-01T00:00:002005Erythropoietin signaling promotes invasiveness of human head and neck squamous cell carcinoma.17028292Lai SY, Grandis JRJournal of clinical oncology : official journal of the American Society of Clinical OncologyUnderstanding the presence and function of erythropoietin receptors on cancer cells. J Clin Oncol. 2006 Oct 10; 24(29):4675-6.J Clin Oncol2006-10-10T00:00:002006Understanding the presence and function of erythropoietin receptors on cancer cells.17075408Deleyiannis FW, Rogers C, Lee E, Russavage J, Gastman B, Dunklebarger J, Lai S, Ferris R, Myers EN, Johnson JThe LaryngoscopeReconstruction of the lateral mandibulectomy defect: management based on prognosis and location and volume of soft tissue resection. Laryngoscope. 2006 Nov; 116(11):2071-80.Laryngoscope2006-11-01T00:00:002006Reconstruction of the lateral mandibulectomy defect: management based on prognosis and location and volume of soft tissue resection.17312569Lin CJ, Grandis JR, Carey TE, Gollin SM, Whiteside TL, Koch WM, Ferris RL, Lai SYHead & neckHead and neck squamous cell carcinoma cell lines: established models and rationale for selection. Head Neck. 2007 Feb; 29(2):163-88.Head Neck2007-02-01T00:00:002007Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.17980765Deleyiannis FW, Dunklebarger J, Lee E, Gastman B, Lai S, Ferris R, Myers EN, Johnson JAmerican journal of otolaryngologyReconstruction of the marginal mandibulectomy defect: an update. Am J Otolaryngol. 2007 Nov-Dec; 28(6):363-6.Am J Otolaryngol2007-11-01T00:00:002007Reconstruction of the marginal mandibulectomy defect: an update.17996485Lai SY, Ziober AF, Lee MN, Cohen NA, Falls EM, Ziober BLOral oncologyActivated Vav2 modulates cellular invasion through Rac1 and Cdc42 in oral squamous cell carcinoma. Oral Oncol. 2008 Jul; 44(7):683-8.Oral Oncol2007-11-09T00:00:002007Activated Vav2 modulates cellular invasion through Rac1 and Cdc42 in oral squamous cell carcinoma.18239938Chiosea SI, Barnes EL, Lai SY, Egloff AM, Sargent RL, Hunt JL, Seethala RRVirchows Archiv : an international journal of pathologyMucoepidermoid carcinoma of upper aerodigestive tract: clinicopathologic study of 78 cases with immunohistochemical analysis of Dicer expression. Virchows Arch. 2008 Jun; 452(6):629-35.Virchows Arch2008-02-01T00:00:002008Mucoepidermoid carcinoma of upper aerodigestive tract: clinicopathologic study of 78 cases with immunohistochemical analysis of Dicer expression.20587661Schwartz DL, Bankson JA, Lemos R, Lai SY, Thittai AK, He Y, Hostetter G, Demeure MJ, Von Hoff DD, Powis GMolecular cancer therapeuticsRadiosensitization and stromal imaging response correlates for the HIF-1 inhibitor PX-478 given with or without chemotherapy in pancreatic cancer. Mol Cancer Ther. 2010 Jul; 9(7):2057-67.Mol Cancer Ther2010-06-29T00:00:002010Radiosensitization and stromal imaging response correlates for the HIF-1 inhibitor PX-478 given with or without chemotherapy in pancreatic cancer.20622897Wheeler SE, Suzuki S, Thomas SM, Sen M, Leeman-Neill RJ, Chiosea SI, Kuan CT, Bigner DD, Gooding WE, Lai SY, Grandis JROncogeneEpidermal growth factor receptor variant III mediates head and neck cancer cell invasion via STAT3 activation. Oncogene. 2010 Sep 16; 29(37):5135-45.Oncogene2010-07-12T00:00:002010Epidermal growth factor receptor variant III mediates head and neck cancer cell invasion via STAT3 activation.21079141Argiris A, Heron DE, Smith RP, Kim S, Gibson MK, Lai SY, Branstetter BF, Posluszny DM, Wang L, Seethala RR, Dacic S, Gooding W, Grandis JR, Johnson JT, Ferris RLJournal of clinical oncology : official journal of the American Society of Clinical OncologyInduction docetaxel, cisplatin, and cetuximab followed by concurrent radiotherapy, cisplatin, and cetuximab and maintenance cetuximab in patients with locally advanced head and neck cancer. J Clin Oncol. 2010 Dec 20; 28(36):5294-300.J Clin Oncol2010-11-15T00:00:002010Induction docetaxel, cisplatin, and cetuximab followed by concurrent radiotherapy, cisplatin, and cetuximab and maintenance cetuximab in patients with locally advanced head and neck cancer.21363880Argiris A, Karamouzis MV, Smith R, Kotsakis A, Gibson MK, Lai SY, Kim S, Branstetter BF, Shuai Y, Romkes M, Wang L, Grandis JR, Ferris RL, Johnson JT, Heron DEAnnals of oncology : official journal of the European Society for Medical OncologyPhase I trial of pemetrexed in combination with cetuximab and concurrent radiotherapy in patients with head and neck cancer. Ann Oncol. 2011 Nov; 22(11):2482-2488.Ann Oncol2011-03-01T00:00:002011Phase I trial of pemetrexed in combination with cetuximab and concurrent radiotherapy in patients with head and neck cancer.21364021Schwartz DL, Bankson J, Bidaut L, He Y, Williams R, Lemos R, Thitai AK, Oh J, Volgin A, Soghomonyan S, Yeh HH, Nishii R, Mukhopadhay U, Alauddin M, Mushkudiani I, Kuno N, Krishnan S, Bornman W, Lai SY, Powis G, Hazle J, Gelovani JMolecular cancer research : MCRHIF-1-dependent stromal adaptation to ischemia mediates in vivo tumor radiation resistance. Mol Cancer Res. 2011 Mar; 9(3):259-70.Mol Cancer Res2011-03-01T00:00:002011HIF-1-dependent stromal adaptation to ischemia mediates in vivo tumor radiation resistance.22090359Sen B, Peng S, Woods DM, Wistuba I, Bell D, El-Naggar AK, Lai SY, Johnson FMClinical cancer research : an official journal of the American Association for Cancer ResearchSTAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma. Clin Cancer Res. 2012 Jan 01; 18(1):127-39.Clin Cancer Res2011-11-16T00:00:002011STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma.22981782Fatani HA, Sunbuli M, Lai SY, Bell DAnnals of diagnostic pathologyPhosphaturic mesenchymal tumor: a report of 6 patients treated at a single institution and comparison with reported series. Ann Diagn Pathol. 2013 Aug; 17(4):319-21.Ann Diagn Pathol2012-09-13T00:00:002012Phosphaturic mesenchymal tumor: a report of 6 patients treated at a single institution and comparison with reported series.23192211Hamilton JD, Lai SY, Ginsberg LEJournal of computer assisted tomographySuperimposed infection in mandibular osteoradionecrosis: diagnosis and outcomes. J Comput Assist Tomogr. 2012 Nov-Dec; 36(6):725-31.J Comput Assist Tomogr2012-11-01T00:00:002012Superimposed infection in mandibular osteoradionecrosis: diagnosis and outcomes.24475215Sandulache VC, Chen Y, Lee J, Rubinstein A, Ramirez MS, Skinner HD, Walker CM, Williams MD, Tailor R, Court LE, Bankson JA, Lai SYPloS oneEvaluation of hyperpolarized [1-??C]-pyruvate by magnetic resonance to detect ionizing radiation effects in real time. PLoS One. 2014; 9(1):e87031.PLoS One2014-01-27T00:00:002014Evaluation of hyperpolarized [1-??C]-pyruvate by magnetic resonance to detect ionizing radiation effects in real time.Authorship 2679614Authorship 2684871Authorship 2688161Authorship 2698353Authorship 271443618438259Deleyiannis FW, Rogers C, Ferris RL, Lai SY, Kim S, Johnson JThe LaryngoscopeReconstruction of the through-and-through anterior mandibulectomy defect: indications and limitations of the double-skin paddle fibular free flap. Laryngoscope. 2008 Aug; 118(8):1329-34.Laryngoscope2008-08-01T00:00:002008Reconstruction of the through-and-through anterior mandibulectomy defect: indications and limitations of the double-skin paddle fibular free flap.18767176Lai SY, Walvekar RR, Ferris RLHead & neckMinimally invasive video-assisted thyroidectomy: expanded indications and oncologic completeness. Head Neck. 2008 Nov; 30(11):1403-7.Head Neck2008-11-01T00:00:002008Minimally invasive video-assisted thyroidectomy: expanded indications and oncologic completeness.19204206Lai SY, Koppikar P, Thomas SM, Childs EE, Egloff AM, Seethala RR, Branstetter BF, Gooding WE, Muthukrishnan A, Mountz JM, Lui VW, Shin DM, Agarwala SS, Johnson R, Couture LA, Myers EN, Johnson JT, Mills G, Argiris A, Grandis JRJournal of clinical oncology : official journal of the American Society of Clinical OncologyIntratumoral epidermal growth factor receptor antisense DNA therapy in head and neck cancer: first human application and potential antitumor mechanisms. J Clin Oncol. 2009 Mar 10; 27(8):1235-42.J Clin Oncol2009-02-09T00:00:002009Intratumoral epidermal growth factor receptor antisense DNA therapy in head and neck cancer: first human application and potential antitumor mechanisms.20713769Lewis CM, Bell DM, Lai SYArchives of otolaryngology--head & neck surgeryPathology quiz case 2. 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