ANJANABHARDWAJANJANA BHARDWAJ9092BHARDWAJ, ANJANAAssistant Professorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson1515 Holcombe BlvdHouston77030-4009TXExperimental TherapeuticsMolecular & Cellular OncologyPediatricsSystems BiologyMD AndersonMIEN-CHIEHUNGMIEN-CHIE HUNG8427HUNG, MIEN-CHIEProfessor1.100660.00200327216research areas5.084360.060126611coauthor of40.12137.2992360similar to1131selected publicationsSHULINLISHULIN LI8595LI, SHULINProfessorGORDON BMILLSGORDON B MILLS8620MILLS, GORDON BProfessorISABELLEBEDROSIANISABELLE BEDROSIAN8959BEDROSIAN, ISABELLEProfessorCONSTANCEALBARRACINCONSTANCE ALBARRACIN8954ALBARRACIN, CONSTANCEProfessorGEORGE ACALINGEORGE A CALIN9408CALIN, GEORGE AProfessorAuthorship 2220542Authorship 2222217Authorship 2258593Authorship 2311061Authorship 2336452Authorship 233651215517885Aggarwal BB, Bhardwaj A, Aggarwal RS, Seeram NP, Shishodia S, Takada YAnticancer researchRole of resveratrol in prevention and therapy of cancer: preclinical and clinical studies. Anticancer Res. 2004 Sep-Oct; 24(5A):2783-840.Anticancer Res2004-09-01T00:00:002004Role of resveratrol in prevention and therapy of cancer: preclinical and clinical studies.15585412Li S, Wilkinson M, Xia X, David M, Xu L, Purkel-Sutton A, Bhardwaj AMolecular therapy : the journal of the American Society of Gene TherapyInduction of IFN-regulated factors and antitumoral surveillance by transfected placebo plasmid DNA. Mol Ther. 2005 Jan; 11(1):112-9.Mol Ther2005-01-01T00:00:002005Induction of IFN-regulated factors and antitumoral surveillance by transfected placebo plasmid DNA.18184911Hu Z, MacLean JA, Bhardwaj A, Wilkinson MFAnnals of the New York Academy of SciencesRegulation and function of the Rhox5 homeobox gene. Ann N Y Acad Sci. 2007 Dec; 1120:72-83.Ann N Y Acad Sci2007-12-01T00:00:002007Regulation and function of the Rhox5 homeobox gene.22322598Bhardwaj A, Song HW, Beildeck M, Kerkhofs S, Castoro R, Shanker S, De Gendt K, Suzuki K, Claessens F, Issa JP, Orgebin-Crist MC, Wilkinson MFMolecular endocrinology (Baltimore, Md.)DNA demethylation-dependent AR recruitment and GATA factors drive Rhox5 homeobox gene transcription in the epididymis. Mol Endocrinol. 2012 Apr; 26(4):538-49.Mol Endocrinol2012-02-09T00:00:002012DNA demethylation-dependent AR recruitment and GATA factors drive Rhox5 homeobox gene transcription in the epididymis.22896900Sharma RN, Bhardwaj A, Behera D, Khanduja KLIndian journal of biochemistry & biophysicsOxidative burden and antioxidant defense system in polymorphonuclear leukocytes of human lung diseases. Indian J Biochem Biophys. 2002 Apr; 39(2):124-9.Indian J Biochem Biophys2002-04-01T00:00:002002Oxidative burden and antioxidant defense system in polymorphonuclear leukocytes of human lung diseases.22900369Khanduja KL, Bhardwaj AIndian journal of biochemistry & biophysicsStable free radical scavenging and antiperoxidative properties of resveratrol compared in vitro with some other bioflavonoids. Indian J Biochem Biophys. 2003 Dec; 40(6):416-22.Indian J Biochem Biophys2003-12-01T00:00:002003Stable free radical scavenging and antiperoxidative properties of resveratrol compared in vitro with some other bioflavonoids.Authorship 2437781Authorship 2459851Authorship 2464941Authorship 2465232Authorship 248829111225982Bhardwaj A, Verma A, Majumdar S, Khanduja KLAsian journal of andrologyStatus of vitamin E and reduced glutathione in semen of oligozoospermic and azoospermic patients. Asian J Androl. 2000 Sep; 2(3):225-8.Asian J Androl2000-09-01T00:00:002000Status of vitamin E and reduced glutathione in semen of oligozoospermic and azoospermic patients.14601641Bhardwaj A, Aggarwal BBJournal of clinical immunologyReceptor-mediated choreography of life and death. J Clin Immunol. 2003 Sep; 23(5):317-32.J Clin Immunol2003-09-01T00:00:002003Receptor-mediated choreography of life and death.15489888Takada Y, Bhardwaj A, Potdar P, Aggarwal BBOncogeneNonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation. Oncogene. 2004 Dec 09; 23(57):9247-58.Oncogene2004-12-09T00:00:002004Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation.15832388Bhardwaj A, Wilkinson MFBioEssays : news and reviews in molecular, cellular and developmental biologyA metabolic enzyme doing double duty as a transcription factor. Bioessays. 2005 May; 27(5):467-71.Bioessays2005-05-01T00:00:002005A metabolic enzyme doing double duty as a transcription factor.17164350Bhardwaj A, Sethi G, Vadhan-Raj S, Bueso-Ramos C, Takada Y, Gaur U, Nair AS, Shishodia S, Aggarwal BBBloodResveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells. Blood. 2007 Mar 15; 109(6):2293-302.Blood2006-12-12T00:00:002006Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.26000884Bhardwaj A, Ganesan N, Tachibana K, Rajapakshe K, Albarracin CT, Gunaratne PH, Coarfa C, Bedrosian IPloS oneAnnexin A1 Preferentially Predicts Poor Prognosis of Basal-Like Breast Cancer Patients by Activating mTOR-S6 Signaling. PLoS One. 2015; 10(5):e0127678.PLoS One2015-05-22T00:00:002015Annexin A1 Preferentially Predicts Poor Prognosis of Basal-Like Breast Cancer Patients by Activating mTOR-S6 Signaling.Authorship 2647513Authorship 2658863Authorship 2663452Authorship 2685201Authorship 269668411683702Khanduja KL, Verma A, Bhardwaj AAndrologiaImpairment of human sperm motility and viability by quercetin is independent of lipid peroxidation. Andrologia. 2001 Sep; 33(5):277-81.Andrologia2001-09-01T00:00:002001Impairment of human sperm motility and viability by quercetin is independent of lipid peroxidation.12587722Khanduja KL, Sangari RK, Bhardwaj AIndian journal of experimental biologyCaffeine, quercetin and alizarin stimulate the exhalation of metabolic products of [14C]-N-nitrosodiethylamine in mice. Indian J Exp Biol. 2002 Jun; 40(6):739-44.Indian J Exp Biol2002-06-01T00:00:002002Caffeine, quercetin and alizarin stimulate the exhalation of metabolic products of [14C]-N-nitrosodiethylamine in mice.15228220Khanduja KL, Bhardwaj A, Kaushik GJournal of nutritional science and vitaminologyResveratrol inhibits N-nitrosodiethylamine-induced ornithine decarboxylase and cyclooxygenase in mice. J Nutr Sci Vitaminol (Tokyo). 2004 Feb; 50(1):61-5.J Nutr Sci Vitaminol (Tokyo)2004-02-01T00:00:002004Resveratrol inhibits N-nitrosodiethylamine-induced ornithine decarboxylase and cyclooxygenase in mice.18212046Bhardwaj A, Rao MK, Kaur R, Buttigieg MR, Wilkinson MFMolecular and cellular biologyGATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells. Mol Cell Biol. 2008 Apr; 28(7):2138-53.Mol Cell Biol2008-01-22T00:00:002008GATA factors and androgen receptor collaborate to transcriptionally activate the Rhox5 homeobox gene in Sertoli cells.21596314Bruno IG, Karam R, Huang L, Bhardwaj A, Lou CH, Shum EY, Song HW, Corbett MA, Gifford WD, Gecz J, Pfaff SL, Wilkinson MFMolecular cellIdentification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay. Mol Cell. 2011 May 20; 42(4):500-10.Mol Cell2011-05-20T00:00:002011Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay.Authorship 2788401Authorship 2899071Authorship 291860524811059Bhardwaj A, Rosen D, Liu M, Liu Y, Hao Q, Ganesan N, Etzel CJ, Gullett A, Albarracin CT, Bedrosian IPloS oneSuppression of Akt-mTOR pathway-a novel component of oncogene induced DNA damage response barrier in breast tumorigenesis. PLoS One. 2014; 9(5):e97076.PLoS One2014-05-08T00:00:002014Suppression of Akt-mTOR pathway-a novel component of oncogene induced DNA damage response barrier in breast tumorigenesis.25331959Rao MK, Matsumoto Y, Richardson ME, Panneerdoss S, Bhardwaj A, Ward JM, Shanker S, Bettegowda A, Wilkinson MFThe Journal of biological chemistryHormone-induced and DNA demethylation-induced relief of a tissue-specific and developmentally regulated block in transcriptional elongation. J Biol Chem. 2014 Dec 19; 289(51):35087-101.J Biol Chem2014-10-20T00:00:002014Hormone-induced and DNA demethylation-induced relief of a tissue-specific and developmentally regulated block in transcriptional elongation.74Professor10Assistant Professor14Associate Professor3Adjunct Associate Professor6Adjunct ProfessorBreast Surgical Oncology28160548Bhardwaj A, Singh H, Rajapakshe K, Tachibana K, Ganesan N, Pan Y, Gunaratne PH, Coarfa C, Bedrosian IOncotargetRegulation of miRNA-29c and its downstream pathways in preneoplastic progression of triple-negative breast cancer. Oncotarget. 2017 Mar 21; 8(12):19645-19660.Oncotarget2017-03-21T00:00:002017Regulation of miRNA-29c and its downstream pathways in preneoplastic progression of triple-negative breast cancer.Authorship 854553Authorship 855178Authorship 866660BloodErratum. Blood. 122:1325-1326.ErratumInternational Journal of Medicine, Biology and the EnvironmentAlizarin inhibits oxidative damage and lung tumors in mice induced by N-nitrosodiethylamine. International Journal of Medicine, Biology and the Environment. 29:85-90.Alizarin inhibits oxidative damage and lung tumors in mice induced by N-nitrosodiethylaminePLoS OneAnnexin A1 preferentially predicts poor prognosis of basal-like breast cancer patients by activating mTOR-S6 signaling. PLoS One. 10.Annexin A1 preferentially predicts poor prognosis of basal-like breast cancer patients by activating mTOR-S6 signalingAuthorship 8881291D018398Chemicals & Drugs49811440.651706Homeodomain ProteinsD012708Anatomy301500.915455Sertoli CellsD019161Chemicals & Drugs2148430.554271Hydroxymethylglutaryl-CoA Reductase InhibitorsD011230Concepts & IdeasDisorders34310480.596064Precancerous ConditionsAuthorship 938642130537987Bhardwaj A, Singh H, Trinidad CM, Albarracin CT, Hunt KK, Bedrosian IBreast cancer research : BCRThe isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer. Breast Cancer Res. 2018 12 11; 20(1):150.Breast Cancer Res2018-12-11T00:00:002018The isomiR-140-3p-regulated mevalonic acid pathway as a potential target for prevention of triple negative breast cancer.PathologyDepartment of MedicineDepartment of Molecular & Cellular BiologyMedicine-Athero & LipoproteinsMolecular & Cellular BiologyBaylor College of MedicineCRISTIANCOARFACRISTIAN COARFA0.000000000000000.000000000000001149COARFA, CRISTIANAssociate ProfessorCHRISTIEBALLANTYNECHRISTIE BALLANTYNE29.70978600000000-95.399866000000002252BALLANTYNE, CHRISTIEProfessorPREETHIGUNARATNEPREETHI GUNARATNE0.000000000000000.000000000000003337GUNARATNE, PREETHIAdjunct Associate ProfessorSALIMVIRANISALIM VIRANI29.70978600000000-95.399866000000003676VIRANI, SALIMAdjunct ProfessorD064726Disorders31811970.485786Triple Negative Breast NeoplasmsAuthorship 980212232204397Ju Z, Bhardwaj A, Embury MD, Singh H, Gunaratne PH, Bedrosian I, Wang JCancersIntegrative Analyses of Multilevel Omics Reveal Preneoplastic Breast to Possess a Molecular Landscape That is Globally Shared with Invasive Basal-Like Breast Cancer (Running Title: Molecular Landscape of Basal-Like Breast Cancer Progression). Cancers (Basel). 2020 Mar 19; 12(3).Cancers (Basel)2020-03-19T00:00:002020Integrative Analyses of Multilevel Omics Reveal Preneoplastic Breast to Possess a Molecular Landscape That is Globally Shared with Invasive Basal-Like Breast Cancer (Running Title: Molecular Landscape of Basal-Like Breast Cancer Progression).Authorship 1003349233092312Ju Z, Bhardwaj A, Embury MD, Singh H, Gunaratne PH, Bedrosian I, Wang JCancersErratum: Ju, Z., et al. Integrative Analyses of Multilevel Omics Reveal Preneoplastic Breast to Possess a Molecular Landscape That Is Globally Shared with Invasive Basal-Like Breast Cancer (Running Title: Molecular Landscape of Basal-Like Breast Cancer Progression). Cancers 2020, 12, 722. Cancers (Basel). 2020 Oct 20; 12(10).Cancers (Basel)2020-10-20T00:00:002020Erratum: Ju, Z., et al. Integrative Analyses of Multilevel Omics Reveal Preneoplastic Breast to Possess a Molecular Landscape That Is Globally Shared with Invasive Basal-Like Breast Cancer (Running Title: Molecular Landscape of Basal-Like Breast Cancer Progression). Cancers 2020, 12, 722.Authorship 1016945133893908Bhardwaj A, Embury MD, Rojo RD, Albarracin C, Bedrosian IBreast cancer research and treatmentEfficacy of fluvastatin and aspirin for prevention of hormonally insensitive breast cancer. Breast Cancer Res Treat. 2021 Jun; 187(2):363-374.Breast Cancer Res Treat2021-04-24T00:00:002021Efficacy of fluvastatin and aspirin for prevention of hormonally insensitive breast cancer.true1Associate ProfessorAssociate ProfessorAuthorship 1035461134902009Bhardwaj A, Sohni A, Lou CH, De Gendt K, Zhang F, Kim E, Subbarayalu P, Chan W, Kerkhofs S, Claessens F, Kimmins S, Rao MK, Meistrich M, Wilkinson MFEndocrinologyConcordant Androgen-Regulated Expression of Divergent Rhox5 Promoters in Sertoli Cells. Endocrinology. 2022 01 01; 163(1).Endocrinology2022-01-01T00:00:002022Concordant Androgen-Regulated Expression of Divergent Rhox5 Promoters in Sertoli Cells.true1Adjunct Associate ProfessorAdjunct Associate ProfessorAuthorship 1038446135296281Bhardwaj A, Embury MD, Ju Z, Wang J, Bedrosian IBMC cancerGene signature associated with resistance to fluvastatin chemoprevention for breast cancer. BMC Cancer. 2022 Mar 17; 22(1):282.BMC Cancer2022-03-17T00:00:002022Gene signature associated with resistance to fluvastatin chemoprevention for breast cancer.Authorship 1051067135869155Bhardwaj A, Rojo RD, Ju Z, Koh A, Tachibana K, Wang J, Bedrosian IScientific reportsThe molecular heterogeneity of the precancerous breast affects drug efficacy. Sci Rep. 2022 07 22; 12(1):12590.Sci Rep2022-07-22T00:00:002022The molecular heterogeneity of the precancerous breast affects drug efficacy.true1ProfessorProfessortrue1Adjunct ProfessorAdjunct ProfessorAuthorship 1080003637744342Mistretta B, Rankothgedera S, Castillo M, Rao M, Holloway K, Bhardwaj A, El Noafal M, Albarracin C, El-Zein R, Rezaei H, Su X, Akbani R, Shao XM, Czerniecki BJ, Karchin R, Bedrosian I, Gunaratne PHFrontiers in immunologyChimeric RNAs reveal putative neoantigen peptides for developing tumor vaccines for breast cancer. Front Immunol. 2023; 14:1188831.Front Immunol2023-09-06T00:00:002023Chimeric RNAs reveal putative neoantigen peptides for developing tumor vaccines for breast cancer.true1ProfessorProfessortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor