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LAVINIA P MIDDLETON

TitleProfessor
InstitutionMD Anderson
DepartmentPathology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Salem A, Wu Y, Ding Q, Middleton LP. Impact of NOTCH1 expression in primary breast adenoid cystic carcinoma. J Clin Pathol. 2024 Mar 12. PMID: 38471758.
      Citations:    Fields:    
    2. Chung HL, Middleton LP, Sun J, Whitman GJ. Immediate and delayed risk of breast cancer associated with classic lobular carcinoma in situ and its variants. Breast Cancer Res Treat. 2024 Mar 12. PMID: 38472593.
      Citations:    Fields:    
    3. Salem A, Wu Y, Albarracin CT, Middleton LP, Kalhor N, Peng Y, Huang X, Aung PP, Chen H, Sahin AA, Ding Q. A Comparative Evaluation of TRPS1 and GATA3 in adenoid cystic, secretory, and acinic cell carcinomas of the breast and salivary gland. Hum Pathol. 2024 Mar; 145:42-47. PMID: 38262580.
      Citations:    Fields:    Translation:Humans
    4. Ye Q, Chen H, Han C, Peng Y, Huang X, Sun H, Wu Y, Albarracin CT, Middleton LP, Sahin AA, Huo L, Ding Q. Nuclear staining for pan-Trk by immunohistochemistry is highly specific for secretory carcinoma of breast: pan-Trk in various subtypes of breast carcinoma. J Clin Pathol. 2023 Aug 16. PMID: 37586834.
      Citations:    Fields:    
    5. Olayinka O, Cox SE, Nasrazadani A, Resetkova E, Ivan D, Middleton LP. Invasive Carcinoma With Skin Adnexal Trichilemmal Hair Follicular Differentiation Occurring in the Breast: A Case Report With Detailed Immunohistochemical and Molecular Analysis. Int J Surg Pathol. 2023 Jul 31; 10668969231189166. PMID: 37525555.
      Citations:    Fields:    
    6. Mouabbi JA, Raghavendra AS, Bassett RL, Christgen M, Middleton L, Teshome M, Nasrazadani A, Hortobagyi G, Hassan A, Tripathy D, Layman RM. Absence of lobular carcinoma in situ is a poor prognostic marker in invasive lobular carcinoma. Eur J Cancer. 2023 09; 191:113250. PMID: 37573674; PMCID: PMC10529602.
      Citations:    Fields:    Translation:Humans
    7. Xie CL, Whitman GJ, Middleton LP, Bevers TB, Bedrosian I, Chung HL. Isolated Flat Epithelial Atypia: Upgrade Outcomes After Multidisciplinary Review-Based Management Using Excision or Imaging Surveillance. J Breast Imaging. 2023 Sep-Oct; 5(5):575-584. PMID: 37744722; PMCID: PMC10516722.
      Citations:    
    8. Zhou P, Chang N, Abraham SC, Albarracin CT, Huo L, Chen H, Ding Q, Resetkova E, Middleton LP, Sahin AA, Bu H, Wu Y. Metastatic nonhematopoietic neoplasms to the breast: a study of 238 cases. Hum Pathol. 2022 07; 125:59-67. PMID: 35447141.
      Citations:    Fields:    Translation:Humans
    9. Yoon EC, Wang G, Parkinson B, Huo L, Peng Y, Wang J, Salisbury T, Wu Y, Chen H, Albarracin CT, Resetkova E, Middleton LP, Krishnamurthy S, Gan Q, Sun H, Huang X, Shen T, Chen W, Parwani AV, Sahin AA, Li Z, Ding Q. TRPS1, GATA3, and SOX10 expression in triple-negative breast carcinoma. Hum Pathol. 2022 07; 125:97-107. PMID: 35413381.
      Citations:    Fields:    Translation:Humans
    10. Wang J, Wang WL, Sun H, Huo L, Wu Y, Chen H, Gan Q, Meis JM, Maloney N, Lazar AJ, Yoon EC, Albarracin CT, Krishnamurthy S, Middleton LP, Resetkova E, Yu W, Tan D, Lu W, Solis Soto LM, Wang S, Wistuba II, Parwani AV, Prieto VG, Sahin AA, Li Z, Ding Q. Expression of TRPS1 in phyllodes tumor and sarcoma of the breast. Hum Pathol. 2022 03; 121:73-80. PMID: 35063444.
      Citations:    Fields:    Translation:Humans
    11. Ronen S, Al-Rohil RN, Keiser E, Jour G, Nagarajan P, Tetzlaff MT, Curry JL, Ivan D, Middleton LP, Torres-Cabala CA, Gershenwald JE, Aung PP, Prieto VG. Discordance in Diagnosis of Melanocytic Lesions and Its Impact on Clinical Management. Arch Pathol Lab Med. 2021 12 01; 145(12):1505-1515. PMID: 33577643.
      Citations:    Fields:    Translation:HumansCells
    12. Del Valle Estopinal M, Middleton LP, Esmaeli B, Patel KP, Nowroozizadeh S, Williams MD. Primary Signet Ring Cell/Histiocytoid Carcinoma of the Eyelid: Clinicopathologic Analysis with Evaluation of the E-Cadherin/?-Catenin Complex and Associated Genetic Alterations. Case Rep Pathol. 2021; 2021:6628150. PMID: 34804623; PMCID: PMC8601830.
      Citations:    
    13. Chung HL, Tso HH, Middleton LP, Sun J, Leung JWT. Axillary Nodal Metastases in Invasive Lobular Carcinoma Versus Invasive Ductal Carcinoma: Comparison of Node Detection and Morphology by Ultrasound. AJR Am J Roentgenol. 2022 01; 218(1):33-41. PMID: 34319162.
      Citations: 1     Fields:    Translation:Humans
    14. Sheu TG, Hunt KK, Middleton LP. MYC and NOTCH1-positive postradiation cutaneous angiosarcoma of the breast. Breast J. 2021 03; 27(3):264-267. PMID: 33527629.
      Citations:    Fields:    Translation:Humans
    15. Oramas DM, Bell D, Middleton LP. Sinonasal analogue HPV related breast multiphenotypic carcinoma, a report of a case with the first description in the breast. Diagn Pathol. 2020 Nov 20; 15(1):137. PMID: 33218360; PMCID: PMC7678216.
      Citations: 1     Fields:    Translation:Humans
    16. Chung HL, Middleton LP. Breast amyloidosis in a dormant plasma cell myeloma. Breast J. 2020 11; 26(11):2263-2264. PMID: 32939920.
      Citations:    Fields:    Translation:Humans
    17. Bouobda GT, Gonzalez CE, Phipps RA, Middleton LP. Value Added Impact of Both Point-of-Care and Laboratory Lactic Acid Analysis When Emergently Evaluating Cancer Patients. Oncol Ther. 2020 Dec; 8(2):277-284. PMID: 32700044; PMCID: PMC7683647.
      Citations:    
    18. Richards D, Ayala AA, Wu Y, Middleton LP. Carcinoma In Situ Involving Sclerosing Adenosis on Core Biopsy: Diagnostic Pearls to Aid the Practicing Clinician and Avoid Overtreatment. Oncol Ther. 2020 Jun; 8(1):81-89. PMID: 32700071; PMCID: PMC7360013.
      Citations:    
    19. Le V, Wagar EA, Phipps RA, Del Guidice RE, Le H, Middleton LP. Improving Patient Experience of Wait Times and Courtesy Through Electronic Sign-in and Notification in the Phlebotomy Clinic. Arch Pathol Lab Med. 2020 06; 144(6):769-775. PMID: 31755777.
      Citations: 2     Fields:    Translation:Humans
    20. Speer ME, Adrada BE, Arribas EM, Hess KR, Middleton LP, Whitman GJ. Imaging of Intracystic Papillary Carcinoma. Curr Probl Diagn Radiol. 2019 Jul - Aug; 48(4):348-352. PMID: 30072190.
      Citations: 3     Fields:    Translation:Humans
    21. Brewster AM, Thomas P, Brown P, Coyne R, Yan Y, Checka C, Middleton L, Do KA, Bevers T. A System-Level Approach to Improve the Uptake of Antiestrogen Preventive Therapy among Women with Atypical Hyperplasia and Lobular Cancer In Situ. Cancer Prev Res (Phila). 2018 05; 11(5):295-302. PMID: 29618460.
      Citations: 1     Fields:    Translation:Humans
    22. Middleton LP, Phipps R, Routbort M, Prieto V, Medeiros LJ, Riben M, Contreras A, Kelley J, Patel K, Bingham J, Wagar EA. Fifteen-Year Journey to High Reliability in Pathology and Laboratory Medicine. Am J Med Qual. 2018 Sep/Oct; 33(5):530-539. PMID: 29512395.
      Citations:    Fields:    
    23. Cardoso F, Bartlett JMS, Slaets L, van Deurzen CHM, van Leeuwen-Stok E, Porter P, Linderholm B, Hedenfalk I, Martens J, Bayani J, van Asperen C, Murray M, Hudis C, Middleton L, Vermeij J, Punie K, Fraser J, Nowaczyk M, Rubio IT, Aebi S, Kelly C, Ruddy KJ, Winer E, Lago LD, Korde L, Benstead K, Bogler O, Goulioti T, Peric A, Aalders KC, Poncet C, Tryfonidis K, Giordano SH, Schr?der C, Nilsson C, Liti?re S. Characterization of male breast cancer: results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program. Ann Oncol. 2018 02 01; 29(2):405-417. PMID: 29092024; PMCID: PMC5834077.
      Citations: 95     Fields:    Translation:Humans
    24. Woodward WA, Fang P, Arriaga L, Gao H, Cohen EN, Reuben JM, Valero V, Le-Petross H, Middleton LP, Babiera GV, Strom EA, Tereffe W, Hoffman K, Smith BD, Buchholz TA, Perkins GH. A phase 2 study of capecitabine and concomitant radiation in women with advanced breast cancer. Int J Radiat Oncol Biol Phys. 2017 11 15; 99(4):777-783. PMID: 28843370; PMCID: PMC6072264.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    25. Zhang S, Huo L, Arribas E, Middleton LP. Adenomyoepithelioma of the breast with associated atypical lobular hyperplasia: a previously unrecognized association with management implications. Ann Diagn Pathol. 2015 Feb; 19(1):20-3. PMID: 25631879.
      Citations: 1     Fields:    Translation:Humans
    26. Khazai L, Middleton LP, Goktepe N, Liu BT, Sahin AA. Breast pathology second review identifies clinically significant discrepancies in over 10% of patients. J Surg Oncol. 2015 Feb; 111(2):192-7. PMID: 25273328.
      Citations: 9     Fields:    Translation:Humans
    27. Middleton LP, Feeley TW, Albright HW, Walters R, Hamilton SH. Second-opinion pathologic review is a patient safety mechanism that helps reduce error and decrease waste. J Oncol Pract. 2014 Jul; 10(4):275-80. PMID: 24695900.
      Citations: 7     Fields:    Translation:Humans
    28. Middleton LP, Sneige N, Coyne R, Shen Y, Dong W, Dempsey P, Bevers TB. Most lobular carcinoma in situ and atypical lobular hyperplasia diagnosed on core needle biopsy can be managed clinically with radiologic follow-up in a multidisciplinary setting. Cancer Med. 2014 Jun; 3(3):492-9. PMID: 24639339; PMCID: PMC4101740.
      Citations: 7     Fields:    Translation:Humans
    29. Wagar EA, Phipps R, Del Guidice R, Middleton LP, Bingham J, Prejean C, Johnson-Hamilton M, Philip P, Le NH, Muses W. Inpatient preanalytic process improvements. Arch Pathol Lab Med. 2013 Dec; 137(12):1753-60. PMID: 24283855.
      Citations:    Fields:    Translation:Humans
    30. Nayak A, Carkaci S, Gilcrease MZ, Liu P, Middleton LP, Bassett RL, Zhang J, Zhang H, Coyne RL, Bevers TB, Sneige N, Huo L. Benign papillomas without atypia diagnosed on core needle biopsy: experience from a single institution and proposed criteria for excision. Clin Breast Cancer. 2013 Dec; 13(6):439-49. PMID: 24119786; PMCID: PMC4605914.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    31. Li X, Deavers MT, Guo M, Liu P, Gong Y, Albarracin CT, Middleton LP, Huo L. The effect of prolonged cold ischemia time on estrogen receptor immunohistochemistry in breast cancer. Mod Pathol. 2013 Jan; 26(1):71-8. PMID: 22899286; PMCID: PMC3881416.
      Citations: 4     Fields:    Translation:Humans
    32. Wu Y, Mittendorf EA, Kelten C, Tucker SL, Wei W, Middleton LP, Broglio K, Buchholz TA, Hunt KK, Sahin AA. Occult axillary lymph node metastases do not have prognostic significance in early stage breast cancer. Cancer. 2012 Mar 15; 118(6):1507-14. PMID: 22009292.
      Citations: 1     Fields:    Translation:Humans
    33. Downs-Kelly E, Bell D, Perkins GH, Sneige N, Middleton LP. Clinical implications of margin involvement by pleomorphic lobular carcinoma in situ. Arch Pathol Lab Med. 2011 Jun; 135(6):737-43. PMID: 21631266.
      Citations: 18     Fields:    Translation:Humans
    34. Langsner RJ, Middleton LP, Sun J, Meric-Bernstam F, Hunt KK, Drezek RA, Yu TK. Wide-field imaging of fluorescent deoxy-glucose in ex vivo malignant and normal breast tissue. Biomed Opt Express. 2011 Jun 01; 2(6):1514-23. PMID: 21698015; PMCID: PMC3114220.
      Citations: 14     
    35. Tian Z, Wei B, Tang F, Wei W, Gilcrease MZ, Huo L, Albarracin CT, Resetkova E, Middleton L, Sahin A, Xing Y, Hunt KK, Chen J, Bu H, Rashid A, Abraham SC, Wu Y. Prognostic significance of tumor grading and staging in mammary carcinomas with neuroendocrine differentiation. Hum Pathol. 2011 Aug; 42(8):1169-77. PMID: 21334720.
      Citations: 20     Fields:    Translation:HumansCells
    36. Rosbach KJ, Shin D, Muldoon TJ, Quraishi MA, Middleton LP, Hunt KK, Meric-Bernstam F, Yu TK, Richards-Kortum RR, Yang W. High-resolution fiber optic microscopy with fluorescent contrast enhancement for the identification of axillary lymph node metastases in breast cancer: a pilot study. Biomed Opt Express. 2010 Sep 16; 1(3):911-922. PMID: 21258518; PMCID: PMC3018063.
      Citations: 10     
    37. Arun BK, Granville LA, Yin G, Middleton LP, Dawood S, Kau SW, Kamal A, Hsu L, Hortobagyi GN, Sahin AA. Glutathione-s-transferase-pi expression in early breast cancer: association with outcome and response to chemotherapy. Cancer Invest. 2010 Jun; 28(5):554-9. PMID: 20210524.
      Citations: 11     Fields:    Translation:Humans
    38. Albarracin C, Edgerton ME, Gilcrease MZ, Huo L, Krishnamurthy S, Middleton LP, Resetkova E, Sahin AA, Sneige N, Fraser WS, Wu Y. Is it too soon to start reporting HER2 genetic heterogeneity? Arch Pathol Lab Med. 2010 Feb; 134(2):162-3; author reply 163. PMID: 20121597.
      Citations: 1     Fields:    Translation:Humans
    39. Dominici LS, Kuerer HM, Babiera G, Hahn KM, Perkins G, Middleton L, Ramirez MM, Yang W, Hortobagyi GN, Theriault RL, Litton JK. Wound complications from surgery in pregnancy-associated breast cancer (PABC). Breast Dis. 2010; 31(1):1-5. PMID: 20519803.
      Citations: 7     Fields:    Translation:Humans
    40. Middleton LP, Price KM, Puig P, Heydon LJ, Tarco E, Sneige N, Barr K, Deavers MT. Implementation of American Society of Clinical Oncology/College of American Pathologists HER2 Guideline Recommendations in a tertiary care facility increases HER2 immunohistochemistry and fluorescence in situ hybridization concordance and decreases the number of inconclusive cases. Arch Pathol Lab Med. 2009 May; 133(5):775-80. PMID: 19415952.
      Citations: 23     Fields:    Translation:Humans
    41. Loya A, Guray M, Hennessy BT, Middleton LP, Buchholz TA, Valero V, Sahin AA. Prognostic significance of occult axillary lymph node metastases after chemotherapy-induced pathologic complete response of cytologically proven axillary lymph node metastases from breast cancer. Cancer. 2009 Apr 15; 115(8):1605-12. PMID: 19197997.
      Citations: 7     Fields:    Translation:Humans
    42. Wagner J, Boughey JC, Garrett B, Babiera G, Kuerer H, Meric-Bernstam F, Singletary E, Hunt KK, Middleton LP, Bedrosian I. Margin assessment after neoadjuvant chemotherapy in invasive lobular cancer. Am J Surg. 2009 Sep; 198(3):387-91. PMID: 19362281; PMCID: PMC4355914.
      Citations: 5     Fields:    Translation:Humans
    43. Beadle BM, Woodward WA, Middleton LP, Tereffe W, Strom EA, Litton JK, Meric-Bernstam F, Theriault RL, Buchholz TA, Perkins GH. The impact of pregnancy on breast cancer outcomes in women PMID: 19204903; PMCID: PMC3063387.
      Citations: 41     Fields:    Translation:Humans
    44. Boughey JC, Wagner J, Garrett BJ, Harker L, Middleton LP, Babiera GV, Meric-Bernstam F, Lucci A, Hunt KK, Bedrosian I. Neoadjuvant chemotherapy in invasive lobular carcinoma may not improve rates of breast conservation. Ann Surg Oncol. 2009 Jun; 16(6):1606-11. PMID: 19280264; PMCID: PMC4338983.
      Citations: 12     Fields:    Translation:Humans
    45. Yi M, Meric-Bernstam F, Middleton LP, Arun BK, Bedrosian I, Babiera GV, Hwang RF, Kuerer HM, Yang W, Hunt KK. Predictors of contralateral breast cancer in patients with unilateral breast cancer undergoing contralateral prophylactic mastectomy. Cancer. 2009 Mar 01; 115(5):962-71. PMID: 19172584; PMCID: PMC4365476.
      Citations: 18     Fields:    Translation:Humans
    46. Kuerer HM, Albarracin CT, Yang WT, Cardiff RD, Brewster AM, Symmans WF, Hylton NM, Middleton LP, Krishnamurthy S, Perkins GH, Babiera G, Edgerton ME, Czerniecki BJ, Arun BK, Hortobagyi GN. Ductal carcinoma in situ: state of the science and roadmap to advance the field. J Clin Oncol. 2009 Jan 10; 27(2):279-88. PMID: 19064970.
      Citations: 56     Fields:    Translation:HumansAnimals
    47. Mathew J, Perkins GH, Stephens T, Middleton LP, Yang WT. Primary breast cancer in men: clinical, imaging, and pathologic findings in 57 patients. AJR Am J Roentgenol. 2008 Dec; 191(6):1631-9. PMID: 19020230.
      Citations: 19     Fields:    Translation:Humans
    48. Gadre SA, Perkins GH, Sahin AA, Sneige N, Deavers MT, Middleton LP. Neovascularization in mucinous ductal carcinoma in situ suggests an alternative pathway for invasion. Histopathology. 2008 Nov; 53(5):545-53. PMID: 18983463.
      Citations: 2     Fields:    Translation:Humans
    49. Wang H, Arun BK, Wang H, Fuller GN, Zhang W, Middleton LP, Sahin AA. IGFBP2 and IGFBP5 overexpression correlates with the lymph node metastasis in T1 breast carcinomas. Breast J. 2008 May-Jun; 14(3):261-7. PMID: 18373644.
      Citations: 25     Fields:    Translation:Humans
    50. Nicolas MM, Wu Y, Middleton LP, Gilcrease MZ. Loss of myoepithelium is variable in solid papillary carcinoma of the breast. Histopathology. 2007 Nov; 51(5):657-65. PMID: 17927587.
      Citations: 8     Fields:    Translation:Humans
    51. Boughey JC, Middleton LP, Harker L, Garrett B, Fornage B, Hunt KK, Babiera GV, Dempsey P, Bedrosian I. Utility of ultrasound and fine-needle aspiration biopsy of the axilla in the assessment of invasive lobular carcinoma of the breast. Am J Surg. 2007 Oct; 194(4):450-5. PMID: 17826054.
      Citations: 9     Fields:    Translation:Humans
    52. Middleton LP, Perkins GH, Tucker SL, Sahin AA, Singletary SE. Expression of ERalpha and ERbeta in lobular carcinoma in situ. Histopathology. 2007 Jun; 50(7):875-80. PMID: 17543077.
      Citations: 4     Fields:    Translation:HumansCells
    53. Woodward WA, Huang EH, McNeese MD, Perkins GH, Tucker SL, Strom EA, Middleton L, Hahn K, Hortobagyi GN, Buchholz TA. African-American race is associated with a poorer overall survival rate for breast cancer patients treated with mastectomy and doxorubicin-based chemotherapy. Cancer. 2006 Dec 01; 107(11):2662-8. PMID: 17061247.
      Citations: 22     Fields:    Translation:Humans
    54. Oh JL, Dryden MJ, Woodward WA, Yu TK, Tereffe W, Strom EA, Perkins GH, Middleton L, Hunt KK, Giordano SH, Oswald MJ, Domain D, Buchholz TA. Locoregional control of clinically diagnosed multifocal or multicentric breast cancer after neoadjuvant chemotherapy and locoregional therapy. J Clin Oncol. 2006 Nov 01; 24(31):4971-5. PMID: 17075114.
      Citations: 16     Fields:    Translation:Humans
    55. Hahn KM, Johnson PH, Gordon N, Kuerer H, Middleton L, Ramirez M, Yang W, Perkins G, Hortobagyi GN, Theriault RL. Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero. Cancer. 2006 Sep 15; 107(6):1219-26. PMID: 16894524.
      Citations: 70     Fields:    Translation:HumansCTClinical Trials
    56. Erguvan-Dogan B, Whitman GJ, Nguyen VA, Dryden MJ, Stafford RJ, Hazle J, McAlee KR, Phelps MJ, Ice MF, Kuerer HM, Middleton LP. Specimen radiography in confirmation of MRI-guided needle localization and surgical excision of breast lesions. AJR Am J Roentgenol. 2006 Aug; 187(2):339-44. PMID: 16861535.
      Citations: 11     Fields:    Translation:Humans
    57. Guarneri V, Broglio K, Kau SW, Cristofanilli M, Buzdar AU, Valero V, Buchholz T, Meric F, Middleton L, Hortobagyi GN, Gonzalez-Angulo AM. Prognostic value of pathologic complete response after primary chemotherapy in relation to hormone receptor status and other factors. J Clin Oncol. 2006 Mar 01; 24(7):1037-44. PMID: 16505422.
      Citations: 190     Fields:    Translation:Humans
    58. Chagpar AB, Middleton LP, Sahin AA, Dempsey P, Buzdar AU, Mirza AN, Ames FC, Babiera GV, Feig BW, Hunt KK, Kuerer HM, Meric-Bernstam F, Ross MI, Singletary SE. Accuracy of physical examination, ultrasonography, and mammography in predicting residual pathologic tumor size in patients treated with neoadjuvant chemotherapy. Ann Surg. 2006 Feb; 243(2):257-64. PMID: 16432360; PMCID: PMC1448900.
      Citations: 66     Fields:    Translation:Humans
    59. Giordano SH, Perkins GH, Broglio K, Garcia SG, Middleton LP, Buzdar AU, Hortobagyi GN. Adjuvant systemic therapy for male breast carcinoma. Cancer. 2005 Dec 01; 104(11):2359-64. PMID: 16270318.
      Citations: 48     Fields:    Translation:Humans
    60. Chagpar A, Middleton LP, Sahin AA, Meric-Bernstam F, Kuerer HM, Feig BW, Ross MI, Ames FC, Singletary SE, Buchholz TA, Valero V, Hunt KK. Clinical outcome of patients with lymph node-negative breast carcinoma who have sentinel lymph node micrometastases detected by immunohistochemistry. Cancer. 2005 Apr 15; 103(8):1581-6. PMID: 15747375.
      Citations: 17     Fields:    Translation:Humans
    61. Maru D, Middleton LP, Wang S, Valero V, Sahin A. HER-2/neu and p53 overexpression as biomarkers of breast carcinoma in women age 30 years and younger. Cancer. 2005 Mar 01; 103(5):900-5. PMID: 15643600.
      Citations: 8     Fields:    Translation:Humans
    62. Vigneswaran N, Wu J, Muller S, Zacharias W, Narendran S, Middleton L. Expression analysis of cystatin C and M in laser-capture microdissectioned human breast cancer cells--a preliminary study. Pathol Res Pract. 2005; 200(11-12):753-62. PMID: 15792117.
      Citations: 9     Fields:    Translation:Humans
    63. Recine MA, Deavers MT, Middleton LP, Silva EG, Malpica A. Serous carcinoma of the ovary and peritoneum with metastases to the breast and axillary lymph nodes: a potential pitfall. Am J Surg Pathol. 2004 Dec; 28(12):1646-51. PMID: 15577686.
      Citations: 33     Fields:    Translation:Humans
    64. Wagner AE, Middleton LP, Whitman GJ. Intracystic papillary carcinoma of the breast with invasion. AJR Am J Roentgenol. 2004 Nov; 183(5):1516. PMID: 15505330.
      Citations: 10     Fields:    Translation:Humans
    65. Sanati S, Ayala AG, Middleton LP. Lymphoepithelioma-like carcinoma of the breast: report of a case mimicking lymphoma. Ann Diagn Pathol. 2004 Oct; 8(5):309-15. PMID: 15494940.
      Citations: 7     Fields:    Translation:HumansCells
    66. Selinko VL, Middleton LP, Dempsey PJ. Role of sonography in diagnosing and staging invasive lobular carcinoma. J Clin Ultrasound. 2004 Sep; 32(7):323-32. PMID: 15293298.
      Citations: 30     Fields:    Translation:Humans
    67. Shahar KH, Hunt KK, Thames HD, Ross MI, Perkins GH, Kuerer HM, Strom EA, McNeese MD, Meric F, Schechter NR, Sahin AA, Middleton LP, Buchholz TA. Factors predictive of having four or more positive axillary lymph nodes in patients with positive sentinel lymph nodes: implications for selection of radiation fields. Int J Radiat Oncol Biol Phys. 2004 Jul 15; 59(4):1074-9. PMID: 15234041.
      Citations: 5     Fields:    Translation:Humans
    68. Yared MA, Middleton LP, Meric F, Cristofanilli M, Sahin AA. Expression of c-kit proto-oncogene product in breast tissue. Breast J. 2004 Jul-Aug; 10(4):323-7. PMID: 15239791.
      Citations: 13     Fields:    Translation:Humans
    69. McGregor DK, Whitman GJ, Middleton LP. Myolipoma of the breast: mammographic, sonographic, and pathologic correlation. Breast J. 2004 May-Jun; 10(3):259-60. PMID: 15125757.
      Citations: 5     Fields:    Translation:Humans
    70. Ivan D, Selinko V, Sahin AA, Sneige N, Middleton LP. Accuracy of core needle biopsy diagnosis in assessing papillary breast lesions: histologic predictors of malignancy. Mod Pathol. 2004 Feb; 17(2):165-71. PMID: 14631369.
      Citations: 15     Fields:    Translation:Humans
    71. Middleton LP, Amin M, Gwyn K, Theriault R, Sahin A. Breast carcinoma in pregnant women: assessment of clinicopathologic and immunohistochemical features. Cancer. 2003 Sep 01; 98(5):1055-60. PMID: 12942575.
      Citations: 53     Fields:    Translation:Humans
    72. Perkins GH, Middleton LP. Breast cancer in men. BMJ. 2003 Aug 02; 327(7409):239-40. PMID: 12896911; PMCID: PMC1126640.
      Citations: 5     Fields:    Translation:Humans
    73. Dogan BE, Whitman GJ, Middleton LP, Phelps M. Intracystic papillary carcinoma of the breast. AJR Am J Roentgenol. 2003 Jul; 181(1):186. PMID: 12818855.
      Citations: 15     Fields:    Translation:Humans
    74. Ramalingam P, Middleton LP, Tamboli P, Troncoso P, Silva EG, Ayala AG. Invasive micropapillary carcinoma of the breast metastatic to the urinary bladder and endometrium: diagnostic pitfalls and review of the literature of tumors with micropapillary features. Ann Diagn Pathol. 2003 Apr; 7(2):112-9. PMID: 12715337.
      Citations: 7     Fields:    Translation:Humans
    75. Diaz LK, Hunt K, Ames F, Meric F, Kuerer H, Babiera G, Ross M, Singletary E, Middleton LP, Symmans WF, Krishnamurthy S, Sahin A, Sneige N, Gilcrease MZ. Histologic localization of sentinel lymph node metastases in breast cancer. Am J Surg Pathol. 2003 Mar; 27(3):385-9. PMID: 12604895.
      Citations: 5     Fields:    Translation:Humans
    76. Gupta D, Middleton LP, Whitaker MJ, Abrams J. Comparison of fluorescence and chromogenic in situ hybridization for detection of HER-2/neu oncogene in breast cancer. Am J Clin Pathol. 2003 Mar; 119(3):381-7. PMID: 12645340.
      Citations: 15     Fields:    Translation:Cells
    77. Middleton LP, Grant S, Stephens T, Stelling CB, Sneige N, Sahin AA. Lobular carcinoma in situ diagnosed by core needle biopsy: when should it be excised? Mod Pathol. 2003 Feb; 16(2):120-9. PMID: 12591964.
      Citations: 21     Fields:    Translation:Humans
    78. Teixeira MR, Pandis N, Heim S. Multicentric mammary carcinoma: evidence of monoclonal proliferation. Cancer. 2003 Feb 01; 97(3):715-7; author reply 717. PMID: 12548617.
      Citations: 2     Fields:    Translation:Humans
    79. Middleton LP, Chen V, Perkins GH, Pinn V, Page D. Histopathology of breast cancer among African-American women. Cancer. 2003 Jan 01; 97(1 Suppl):253-7. PMID: 12491489.
      Citations: 11     Fields:    Translation:Humans
    80. Cserni G. Sentinel lymph node histopathology in breast cancer. Am J Surg Pathol. 2002 Oct; 26(10):1368; author reply 1368. PMID: 12360053.
      Citations: 1     Fields:    Translation:Humans
    81. Solorzano CC, Middleton LP, Hunt KK, Mirza N, Meric F, Kuerer HM, Ross MI, Ames FC, Feig BW, Pollock RE, Singletary SE, Babiera G. Treatment and outcome of patients with intracystic papillary carcinoma of the breast. Am J Surg. 2002 Oct; 184(4):364-8. PMID: 12383904.
      Citations: 39     Fields:    Translation:Humans
    82. Gupta D, Wolf JA, Rubenchik IA, Middleton LP. Diagnostic pitfalls in fine needle aspiration cytology of atypical apocrine metaplasia in a breast lesion. A case report. Acta Cytol. 2002 Jul-Aug; 46(4):749-52. PMID: 12146046.
      Citations:    Fields:    Translation:HumansCells
    83. Wang J, Buchholz TA, Middleton LP, Allred DC, Tucker SL, Kuerer HM, Esteva FJ, Hortobagyi GN, Sahin AA. Assessment of histologic features and expression of biomarkers in predicting pathologic response to anthracycline-based neoadjuvant chemotherapy in patients with breast carcinoma. Cancer. 2002 Jun 15; 94(12):3107-14. PMID: 12115341.
      Citations: 24     Fields:    Translation:Humans
    84. Gupta D, Croitoru CM, Ayala AG, Sahin AA, Middleton LP. E-cadherin immunohistochemical analysis of histiocytoid carcinoma of the breast. Ann Diagn Pathol. 2002 06; 6(3):141-7. PMID: 12089723.
      Citations: 9     Fields:    Translation:HumansCells
    85. Middleton LP, Vlastos G, Mirza NQ, Eva S, Sahin AA. Multicentric mammary carcinoma: evidence of monoclonal proliferation. Cancer. 2002 Apr 01; 94(7):1910-6. PMID: 11932891.
      Citations: 12     Fields:    Translation:Humans
    86. Yared MA, Middleton LP, Smith TL, Kim HW, Ross MI, Hunt KK, Sahin AA. Recommendations for sentinel lymph node processing in breast cancer. Am J Surg Pathol. 2002 Mar; 26(3):377-82. PMID: 11859211.
      Citations: 12     Fields:    Translation:Humans
    87. Gupta D, Merino MI, Farhood A, Middleton LP. Metastases to breast simulating ductal carcinoma in situ: report of two cases and review of the literature. Ann Diagn Pathol. 2001 Feb; 5(1):15-20. PMID: 11172202.
      Citations: 11     Fields:    Translation:Humans
    88. Lei JY, Middleton LP, Guo XD, Duray PH, McWilliams G, Linehan WM, Merino MJ. Pigmented renal clear cell carcinoma with melanocytic differentiation. Hum Pathol. 2001 Feb; 32(2):233-6. PMID: 11230713.
      Citations: 3     Fields:    Translation:HumansCells
    89. Middleton LP, Palacios DM, Bryant BR, Krebs P, Otis CN, Merino MJ. Pleomorphic lobular carcinoma: morphology, immunohistochemistry, and molecular analysis. Am J Surg Pathol. 2000 Dec; 24(12):1650-6. PMID: 11117786.
      Citations: 34     Fields:    Translation:HumansCells
    90. Middleton LP, Tressera F, Sobel ME, Bryant BR, Alburquerque A, Grases P, Merino MJ. Infiltrating micropapillary carcinoma of the breast. Mod Pathol. 1999 May; 12(5):499-504. PMID: 10349988.
      Citations: 16     Fields:    Translation:HumansCells
    91. Middleton LP, Merino MJ, Popok SM, Ordonez NG, Ayala AG, Ro JY. Male adnexal tumour of probable Wolffian origin occurring in a seminal vesicle. Histopathology. 1998 Sep; 33(3):269-74. PMID: 9777394.
      Citations: 1     Fields:    Translation:Humans
    92. Quezado MM, Middleton LP, Bryant B, Lane K, Weiss SW, Merino MJ. Allelic loss on chromosome 22q in epithelioid sarcomas. Hum Pathol. 1998 Jun; 29(6):604-8. PMID: 9635681.
      Citations: 5     Fields:    Translation:HumansCells
    93. Middleton LP, Duray PH, Merino MJ. The histological spectrum of hemangiopericytoma: application of immunohistochemical analysis including proliferative markers to facilitate diagnosis and predict prognosis. Hum Pathol. 1998 Jun; 29(6):636-40. PMID: 9635686.
      Citations: 12     Fields:    Translation:Humans
    94. Kalaydjieva L, Nikolova A, Turnev I, Petrova J, Hristova A, Ishpekova B, Petkova I, Shmarov A, Stancheva S, Middleton L, Merlini L, Trogu A, Muddle JR, King RH, Thomas PK. Hereditary motor and sensory neuropathy--Lom, a novel demyelinating neuropathy associated with deafness in gypsies. Clinical, electrophysiological and nerve biopsy findings. Brain. 1998 Mar; 121 ( Pt 3):399-408. PMID: 9549516.
      Citations: 29     Fields:    Translation:Humans
    95. Kalaydjieva L, Hallmayer J, Chandler D, Savov A, Nikolova A, Angelicheva D, King RH, Ishpekova B, Honeyman K, Calafell F, Shmarov A, Petrova J, Turnev I, Hristova A, Moskov M, Stancheva S, Petkova I, Bittles AH, Georgieva V, Middleton L, Thomas PK. Gene mapping in Gypsies identifies a novel demyelinating neuropathy on chromosome 8q24. Nat Genet. 1996 Oct; 14(2):214-7. PMID: 8841199.
      Citations: 39     Fields:    Translation:HumansCells
    96. Waddy HM, Misra VP, King RH, Thomas PK, Middleton L, Ormerod IE. Focal cranial nerve involvement in chronic inflammatory demyelinating polyneuropathy: clinical and MRI evidence of peripheral and central lesions. J Neurol. 1989 Oct; 236(7):400-5. PMID: 2809641.
      Citations: 11     Fields:    Translation:HumansCells
    97. Holt IJ, Harding AE, Middleton L, Chrysostomou G, Said G, King RH, Thomas PK. Molecular genetics of amyloid neuropathy in Europe. Lancet. 1989 Mar 11; 1(8637):524-6. PMID: 2564060.
      Citations: 8     Fields:    Translation:Humans
    98. Inpatient preanalytic process improvements. Archives of Pathology and Laboratory Medicine. 137:1753-1760.
    99. Age-Related Lobular Involution and Risk of Breast Cancer. Breast Diseases. 19:50-51.
    100. Needle core biopsy in the diagnosis of phyllodes neoplasm. Breast Diseases. 19:50.
    101. Should the Extent of Lobular Neoplasia on Core Biopsy Influence the Decision for Excision?. Breast Diseases. 19:145-146.
    102. Pathologic findings from the national surgical adjuvant breast and bowel project. Breast Diseases. 15:274-275.
    103. Breast carcinoma in pregnant women. Breast Diseases. 15:44.
    104. Tubular carcinoma of the breast. Breast Diseases. 22:33-34.
    105. 2-18 Prediction of BRCA1 Status in Patients With Breast Cancer Using Estrogen Receptor and Basal Phenotype. Breast Diseases. 17:152.
    106. Pleomorphic Lobular Carcinoma of the Breast. Breast Diseases. 17:241.
    107. Current Multidisciplinary Management of High-Risk Breast Lesions. Current Breast Cancer Reports. 7:81-89.
    108. Correlation of tumor volume and surface area with lymph node status in patients with multifocal/multicentric breast carcinoma. Breast Diseases. 15:277-278.
    109. 2-17 Placental Cadherin and the Basal Epithelial Phenotype of BRCA1-Related Breast Cancer. Breast Diseases. 17:151.
    110. Preoperative Profiling of Symptomatic Breast Cancer by Diagnostic Core Biopsy. Breast Diseases. 18:66.
    111. The diagnosis of pleomorphic lobular carcinoma in situ warrants complete excision with negative margins. Current Breast Cancer Reports. 4:96-101.
    112. Breast conservation therapy for invasive lobular carcinoma. Breast Diseases. 16:178.
    113. False-negative core needle biopsies of the breast. Breast Diseases. 15:45.
    114. Utility of four-quadrant random sections in mastectomy specimens. Breast Diseases. 15:159-160.
    115. E-Cadherin Status in Breast Cancer Correlates With Histologic Type but Does Not Correlate With Established Prognostic Parameters. Breast Diseases. 18:66.
    116. Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type. Breast Diseases. 22:154-155.
    117. High-resolution fiber optic microscopy with fluorescent contrast enhancement for the identification of axillary lymph node metastases in breast cancer. Biomedical Optics Express. 1:911-922.
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