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VICKI D HUFF

TitleProfessor
InstitutionMD Anderson
DepartmentGenetics
Address6767 Bertner St
Houston TX 77030-2603
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Aloway JA, Ruteshouser EC, Huff V, Behringer RR. Generation of a Wt1 conditional deletion, nuclear red fluorescent protein reporter allele in the mouse. Differentiation. 2024 Jul-Aug; 138:100791. PMID: 38941819.
      Citations:    Fields:    Translation:Animals
    2. Garner M, Rajani B, Vaidya P, Dayeh SA, Cecchi AC, Miyake CC, Huff V, Wanat M, Wang E, Kurzlechner LM, Landstrom AP, An D, Liang Y, Moulik M, Wong TC, Cunha SR, Cannon A, Holt RL, Milewicz DM, Prakash SK, Garner M, Rajani B, Vaidya P, Dayeh SA, Cecchi AC, Miyake CC, Huff V, Wanat M, Wang E, Kurzlechner LM, Landstrom AP, An D, Liang Y, Moulik M, Wong TC, Cunha SR, Cannon A, Holt RL, Milewicz DM, Prakash SK. The UTHealth Houston Adult Cardiovascular Genomics Certificate Program: Efficacy and Impact on Healthcare Professionals. Res Sq. 2024 Jun 13. PMID: 38947076; PMCID: PMC11213163.
      Citations:    
    3. Murphy AJ, Cheng C, Williams J, Shaw TI, Pinto EM, Dieseldorff-Jones K, Brzezinski J, Renfro LA, Tornwall B, Huff V, Hong AL, Mullen EA, Crompton B, Dome JS, Fernandez CV, Geller JI, Ehrlich PF, Mulder H, Oak N, Maciezsek J, Jablonowski CM, Fleming AM, Pichavaram P, Morton CL, Easton J, Nichols KE, Clay MR, Santiago T, Zhang J, Yang J, Zambetti GP, Wang Z, Davidoff AM, Chen X. Genetic and epigenetic features of bilateral Wilms tumor predisposition in patients from the Children's Oncology Group AREN18B5-Q. Nat Commun. 2023 Dec 18; 14(1):8006. PMID: 38110397; PMCID: PMC10728430.
      Citations: 3     Fields:    Translation:HumansCells
    4. Perotti D, Williams RD, Wegert J, Brzezinski J, Maschietto M, Ciceri S, Gisselsson D, Gadd S, Walz AL, Furtwaengler R, Drost J, Al-Saadi R, Evageliou N, Gooskens SL, Hong AL, Murphy AJ, Ortiz MV, O'Sullivan MJ, Mullen EA, van den Heuvel-Eibrink MM, Fernandez CV, Graf N, Grundy PE, Geller JI, Dome JS, Perlman EJ, Gessler M, Huff V, Pritchard-Jones K. Hallmark discoveries in the biology of Wilms tumour. Nat Rev Urol. 2024 03; 21(3):158-180. PMID: 37848532.
      Citations:    Fields:    Translation:Humans
    5. Murphy AJ, Cheng C, Williams J, Shaw TI, Pinto EM, Dieseldorff-Jones K, Brzezinski J, Renfro LA, Tornwall B, Huff V, Hong AL, Mullen EA, Crompton B, Dome JS, Fernandez CV, Geller JI, Ehrlich PF, Mulder H, Oak N, Maciezsek J, Jablonowski C, Fleming AM, Pichavaram P, Morton CL, Easton J, Nichols KE, Clay MR, Santiago T, Zhang J, Yang J, Zambetti GP, Wang Z, Davidoff AM, Chen X. The Genetic and Epigenetic Features of Bilateral Wilms Tumor Predisposition: A Report from the Children's Oncology Group AREN18B5-Q Study. Res Sq. 2023 Mar 16. PMID: 36993649; PMCID: PMC10055651.
      Citations:    
    6. Gadd S, Huff V, Skol AD, Renfro LA, Fernandez CV, Mullen EA, Jones CD, Hoadley KA, Yap KL, Ramirez NC, Aris S, Phung QH, Perlman EJ. Genetic changes associated with relapse in favorable histology Wilms tumor: A Children's Oncology Group AREN03B2 study. Cell Rep Med. 2022 06 21; 3(6):100644. PMID: 35617957; PMCID: PMC9244995.
      Citations: 1     Fields:    Translation:Humans
    7. Mariottini C, Munari L, Gunzel E, Seco JM, Tzavaras N, Hansen J, Stern SA, Gao V, Aleyasin H, Sharma A, Azeloglu EU, Hodes GE, Russo SJ, Huff V, Birtwistle MR, Blitzer RD, Alberini CM, Iyengar R. Wilm's tumor 1 promotes memory flexibility. Nat Commun. 2019 08 21; 10(1):3756. PMID: 31434897; PMCID: PMC6704057.
      Citations: 3     Fields:    Translation:AnimalsCells
    8. Armstrong AE, Gadd S, Huff V, Gerhard DS, Dome JS, Perlman EJ. A unique subset of low-risk Wilms tumors is characterized by loss of function of TRIM28 (KAP1), a gene critical in early renal development: A Children's Oncology Group study. PLoS One. 2018; 13(12):e0208936. PMID: 30543698; PMCID: PMC6292605.
      Citations: 10     Fields:    Translation:HumansCells
    9. Annesley CE, Rabik C, Duffield AS, Rau RE, Magoon D, Li L, Huff V, Small D, Loeb DM, Brown P. Knock-in of the Wt1 R394W mutation causes MDS and cooperates with Flt3/ITD to drive aggressive myeloid neoplasms in mice. Oncotarget. 2018 Oct 19; 9(82):35313-35326. PMID: 30450160; PMCID: PMC6219680.
      Citations: 6     Fields:    
    10. Gadd S, Huff V, Walz AL, Ooms AHAG, Armstrong AE, Gerhard DS, Smith MA, Auvil JMG, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Hermida LC, Davidsen T, Gesuwan P, Ma Y, Zong Z, Mungall AJ, Moore RA, Marra MA, Dome JS, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Ross N, Gastier-Foster JM, Arold ST, Perlman EJ. A Children's Oncology Group and TARGET initiative exploring the genetic landscape of Wilms tumor. Nat Genet. 2017 Oct; 49(10):1487-1494. PMID: 28825729; PMCID: PMC5712232.
      Citations: 103     Fields:    Translation:HumansCells
    11. Chen M, Zhang L, Cui X, Lin X, Li Y, Wang Y, Wang Y, Qin Y, Chen D, Han C, Zhou B, Huff V, Gao F. Wt1 directs the lineage specification of sertoli and granulosa cells by repressing Sf1 expression. Development. 2017 01 01; 144(1):44-53. PMID: 27888191.
      Citations: 26     Fields:    Translation:AnimalsCells
    12. Ooms AH, Gadd S, Gerhard DS, Smith MA, Guidry Auvil JM, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Ma Y, Zong Z, Mungall AJ, Moore RA, Marra MA, Huff V, Dome JS, Chi YY, Tian J, Geller JI, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Walz AL, van den Heuvel-Eibrink MM, de Krijger RR, Ross N, Gastier-Foster JM, Perlman EJ. Significance of TP53 Mutation in Wilms Tumors with Diffuse Anaplasia: A Report from the Children's Oncology Group. Clin Cancer Res. 2016 Nov 15; 22(22):5582-5591. PMID: 27702824; PMCID: PMC5290091.
      Citations: 30     Fields:    Translation:Humans
    13. Huang L, Mokkapati S, Hu Q, Ruteshouser EC, Hicks MJ, Huff V. Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with ?-Catenin Activation or Wt1 Ablation and Igf2 Upregulation. Neoplasia. 2016 Feb; 18(2):71-81. PMID: 26936393; PMCID: PMC5005262.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    14. Perlman EJ, Gadd S, Arold ST, Radhakrishnan A, Gerhard DS, Jennings L, Huff V, Guidry Auvil JM, Davidsen TM, Dome JS, Meerzaman D, Hsu CH, Nguyen C, Anderson J, Ma Y, Mungall AJ, Moore RA, Marra MA, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Gastier-Foster JM, Ross N, Smith MA. MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours. Nat Commun. 2015 Dec 04; 6:10013. PMID: 26635203; PMCID: PMC4686660.
      Citations: 20     Fields:    Translation:HumansCells
    15. Palculict TB, Ruteshouser EC, Fan Y, Wang W, Strong L, Huff V. Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour. J Med Genet. 2016 06; 53(6):385-8. PMID: 26566882; PMCID: PMC4866907.
      Citations: 10     Fields:    Translation:Humans
    16. Zhang L, Chen M, Wen Q, Li Y, Wang Y, Wang Y, Qin Y, Cui X, Yang L, Huff V, Gao F. Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation. Proc Natl Acad Sci U S A. 2015 Mar 31; 112(13):4003-8. PMID: 25775596; PMCID: PMC4386376.
      Citations: 27     Fields:    Translation:AnimalsCells
    17. Walz AL, Ooms A, Gadd S, Gerhard DS, Smith MA, Guidry Auvil JM, Guidry Auvil JM, Meerzaman D, Chen QR, Hsu CH, Yan C, Nguyen C, Hu Y, Bowlby R, Brooks D, Ma Y, Mungall AJ, Moore RA, Schein J, Marra MA, Huff V, Dome JS, Chi YY, Mullighan CG, Ma J, Wheeler DA, Hampton OA, Jafari N, Ross N, Gastier-Foster JM, Perlman EJ. Recurrent DGCR8, DROSHA, and SIX homeodomain mutations in favorable histology Wilms tumors. Cancer Cell. 2015 Feb 09; 27(2):286-97. PMID: 25670082; PMCID: PMC4800737.
      Citations: 112     Fields:    Translation:Humans
    18. Shukrun R, Pode-Shakked N, Pleniceanu O, Omer D, Vax E, Peer E, Pri-Chen S, Jacob J, Hu Q, Harari-Steinberg O, Huff V, Dekel B. Wilms' tumor blastemal stem cells dedifferentiate to propagate the tumor bulk. Stem Cell Reports. 2014 Jul 08; 3(1):24-33. PMID: 25068119; PMCID: PMC4110791.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    19. Maturu P, Overwijk WW, Hicks J, Ekmekcioglu S, Grimm EA, Huff V. Characterization of the inflammatory microenvironment and identification of potential therapeutic targets in wilms tumors. Transl Oncol. 2014 Aug; 7(4):484-92. PMID: 24969538; PMCID: PMC4202801.
      Citations: 20     
    20. Mokkapati S, Niopek K, Huang L, Cunniff KJ, Ruteshouser EC, deCaestecker M, Finegold MJ, Huff V. ?-catenin activation in a novel liver progenitor cell type is sufficient to cause hepatocellular carcinoma and hepatoblastoma. Cancer Res. 2014 Aug 15; 74(16):4515-25. PMID: 24848510; PMCID: PMC4134699.
      Citations: 41     Fields:    Translation:AnimalsCells
    21. Libes JM, Seeley EH, Li M, Axt JR, Pierce J, Correa H, Newton M, Hansen E, Judd A, McDonald H, Caprioli RM, Naranjo A, Huff V, O'Neill JA, Lovvorn HN, Kenyan Wilms Tumor Consortium. Race disparities in peptide profiles of North American and Kenyan Wilms tumor specimens. J Am Coll Surg. 2014 Apr; 218(4):707-20. PMID: 24655859; PMCID: PMC3964369.
      Citations: 11     Fields:    Translation:Humans
    22. Gao F, Zhang J, Wang X, Yang J, Chen D, Huff V, Liu YX. Wt1 functions in ovarian follicle development by regulating granulosa cell differentiation. Hum Mol Genet. 2014 Jan 15; 23(2):333-41. PMID: 24009315.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    23. Wang XN, Li ZS, Ren Y, Jiang T, Wang YQ, Chen M, Zhang J, Hao JX, Wang YB, Sha RN, Huang Y, Liu X, Hu JC, Sun GQ, Li HG, Xiong CL, Xie J, Jiang ZM, Cai ZM, Wang J, Wang J, Huff V, Gui YT, Gao F. The Wilms tumor gene, Wt1, is critical for mouse spermatogenesis via regulation of sertoli cell polarity and is associated with non-obstructive azoospermia in humans. PLoS Genet. 2013; 9(8):e1003645. PMID: 23935527; PMCID: PMC3731222.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    24. Flores LG, Yeh HH, Soghomonyan S, Young D, Bankson J, Hu Q, Alauddin M, Huff V, Gelovani JG. Monitoring therapy with MEK inhibitor U0126 in a novel Wilms tumor model in Wt1 knockout Igf2 transgenic mice using 18F-FDG PET with dual-contrast enhanced CT and MRI: early metabolic response without inhibition of tumor growth. Mol Imaging Biol. 2013 Apr; 15(2):175-85. PMID: 22875335; PMCID: PMC3591528.
      Citations: 8     Fields:    Translation:Animals
    25. Kaftanovskaya EM, Neukirchner G, Huff V, Agoulnik AI. Left-sided cryptorchidism in mice with Wilms' tumour 1 gene deletion in gubernaculum testis. J Pathol. 2013 May; 230(1):39-47. PMID: 23288785; PMCID: PMC3819214.
      Citations: 7     Fields:    Translation:Animals
    26. Peng G, Fan Y, Palculict TB, Shen P, Ruteshouser EC, Chi AK, Davis RW, Huff V, Scharfe C, Wang W. Rare variant detection using family-based sequencing analysis. Proc Natl Acad Sci U S A. 2013 Mar 05; 110(10):3985-90. PMID: 23426633; PMCID: PMC3593912.
      Citations: 30     Fields:    Translation:Humans
    27. Shahidul Makki M, Cristy Ruteshouser E, Huff V. Ubiquitin specific protease 18 (Usp18) is a WT1 transcriptional target. Exp Cell Res. 2013 Mar 10; 319(5):612-22. PMID: 23291318; PMCID: PMC3791519.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    28. Dome JS, Fernandez CV, Mullen EA, Kalapurakal JA, Geller JI, Huff V, Gratias EJ, Dix DB, Ehrlich PF, Khanna G, Malogolowkin MH, Anderson JR, Naranjo A, Perlman EJ, COG Renal Tumors Committee. Children's Oncology Group's 2013 blueprint for research: renal tumors. Pediatr Blood Cancer. 2013 Jun; 60(6):994-1000. PMID: 23255438; PMCID: PMC4127041.
      Citations: 63     Fields:    Translation:Humans
    29. Gadd S, Huff V, Huang CC, Ruteshouser EC, Dome JS, Grundy PE, Breslow N, Jennings L, Green DM, Beckwith JB, Perlman EJ. Clinically relevant subsets identified by gene expression patterns support a revised ontogenic model of Wilms tumor: a Children's Oncology Group Study. Neoplasia. 2012 Aug; 14(8):742-56. PMID: 22952427; PMCID: PMC3431181.
      Citations: 52     Fields:    Translation:HumansCells
    30. Gadd S, Beezhold P, Jennings L, George D, Leuer K, Huang CC, Huff V, Tognon C, Sorensen PH, Triche T, Coffin CM, Perlman EJ. Mediators of receptor tyrosine kinase activation in infantile fibrosarcoma: a Children's Oncology Group study. J Pathol. 2012 Sep; 228(1):119-30. PMID: 22374738.
      Citations: 13     Fields:    Translation:Humans
    31. Huff V. Wilms' tumours: about tumour suppressor genes, an oncogene and a chameleon gene. Nat Rev Cancer. 2011 Feb; 11(2):111-21. PMID: 21248786; PMCID: PMC4332715.
      Citations: 97     Fields:    Translation:Humans
    32. Perlman EJ, Grundy PE, Anderson JR, Jennings LJ, Green DM, Dome JS, Shamberger RC, Ruteshouser EC, Huff V. WT1 mutation and 11P15 loss of heterozygosity predict relapse in very low-risk wilms tumors treated with surgery alone: a children's oncology group study. J Clin Oncol. 2011 Feb 20; 29(6):698-703. PMID: 21189373; PMCID: PMC3056654.
      Citations: 20     Fields:    Translation:HumansCells
    33. Hu Q, Gao F, Tian W, Ruteshouser EC, Wang Y, Lazar A, Stewart J, Strong LC, Behringer RR, Huff V. Wt1 ablation and Igf2 upregulation in mice result in Wilms tumors with elevated ERK1/2 phosphorylation. J Clin Invest. 2011 Jan; 121(1):174-83. PMID: 21123950; PMCID: PMC3007149.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    34. Vicent S, Chen R, Sayles LC, Lin C, Walker RG, Gillespie AK, Subramanian A, Hinkle G, Yang X, Saif S, Root DE, Huff V, Hahn WC, Sweet-Cordero EA. Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models. J Clin Invest. 2010 Nov; 120(11):3940-52. PMID: 20972333; PMCID: PMC2965578.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    35. Shamberger RC, Anderson JR, Breslow NE, Perlman EJ, Beckwith JB, Ritchey ML, Haase GM, Donaldson M, Grundy PE, Weetman R, Coppes MJ, Malogolowkin M, Shearer PD, Kletzel M, Thomas PR, Macklis R, Huff V, Weeks DA, Green DM. Long-term outcomes for infants with very low risk Wilms tumor treated with surgery alone in National Wilms Tumor Study-5. Ann Surg. 2010 Mar; 251(3):555-8. PMID: 20142733; PMCID: PMC2836016.
      Citations: 22     Fields:    Translation:Humans
    36. Subbiah V, Huff V, Wolff JE, Ketonen L, Lang FF, Stewart J, Langford L, Herzog CE. Bilateral gonadoblastoma with dysgerminoma and pilocytic astrocytoma with WT1 GT-IVS9 mutation: A 46 XY phenotypic female with Frasier syndrome. Pediatr Blood Cancer. 2009 Dec 15; 53(7):1349-51. PMID: 19653292.
      Citations: 6     Fields:    Translation:HumansCells
    37. Drake KM, Ruteshouser EC, Natrajan R, Harbor P, Wegert J, Gessler M, Pritchard-Jones K, Grundy P, Dome J, Huff V, Jones C, Aldred MA. Loss of heterozygosity at 2q37 in sporadic Wilms' tumor: putative role for miR-562. Clin Cancer Res. 2009 Oct 01; 15(19):5985-92. PMID: 19789318; PMCID: PMC2756455.
      Citations: 26     Fields:    Translation:HumansCells
    38. Ruteshouser EC, Robinson SM, Huff V. Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors. Genes Chromosomes Cancer. 2008 Jun; 47(6):461-70. PMID: 18311776; PMCID: PMC4332772.
      Citations: 75     Fields:    Translation:HumansCells
    39. Chang H, Gao F, Guillou F, Taketo MM, Huff V, Behringer RR. Wt1 negatively regulates beta-catenin signaling during testis development. Development. 2008 May; 135(10):1875-85. PMID: 18403409; PMCID: PMC4038296.
      Citations: 72     Fields:    Translation:AnimalsCells
    40. Katzman PJ, Arnold GL, Lagoe EC, Huff V. Universal nephroblastomatosis with bilateral hyperplastic nephromegaly in siblings. Pediatr Dev Pathol. 2009 Jan-Feb; 12(1):47-52. PMID: 18275253.
      Citations: 3     Fields:    Translation:Humans
    41. Malogolowkin M, Cotton CA, Green DM, Breslow NE, Perlman E, Miser J, Ritchey ML, Thomas PR, Grundy PE, D'Angio GJ, Beckwith JB, Shamberger RC, Haase GM, Donaldson M, Weetman R, Coppes MJ, Shearer P, Coccia P, Kletzel M, Macklis R, Tomlinson G, Huff V, Newbury R, Weeks D, National Wilms Tumor Study Group. Treatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A report from the National Wilms Tumor Study Group. Pediatr Blood Cancer. 2008 Feb; 50(2):236-41. PMID: 17539021.
      Citations: 47     Fields:    Translation:HumansCTClinical Trials
    42. Green DM, Cotton CA, Malogolowkin M, Breslow NE, Perlman E, Miser J, Ritchey ML, Thomas PR, Grundy PE, D'Angio GJ, Beckwith JB, Shamberger RC, Haase GM, Donaldson M, Weetman R, Coppes MJ, Shearer P, Coccia P, Kletzel M, Macklis R, Tomlinson G, Huff V, Newbury R, Weeks D. Treatment of Wilms tumor relapsing after initial treatment with vincristine and actinomycin D: a report from the National Wilms Tumor Study Group. Pediatr Blood Cancer. 2007 May; 48(5):493-9. PMID: 16547940.
      Citations: 19     Fields:    Translation:Humans
    43. Huff V. Wilms tumor genetics: a new, UnX-pected twist to the story. Cancer Cell. 2007 Feb; 11(2):105-7. PMID: 17292822.
      Citations: 2     Fields:    Translation:HumansCells
    44. Gao F, Maiti S, Alam N, Zhang Z, Deng JM, Behringer RR, Guillou F, Huff V, L?cureuil C. The Wilms tumor gene, Wt1, is required for Sox9 expression and maintenance of tubular architecture in the developing testis. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):11987-92. PMID: 16877546; PMCID: PMC1567685.
      Citations: 80     Fields:    Translation:AnimalsCells
    45. Grundy PE, Breslow NE, Li S, Perlman E, Beckwith JB, Ritchey ML, Shamberger RC, Haase GM, D'Angio GJ, Donaldson M, Coppes MJ, Malogolowkin M, Shearer P, Thomas PR, Macklis R, Tomlinson G, Huff V, Green DM, National Wilms Tumor Study Group. Loss of heterozygosity for chromosomes 1p and 16q is an adverse prognostic factor in favorable-histology Wilms tumor: a report from the National Wilms Tumor Study Group. J Clin Oncol. 2005 Oct 10; 23(29):7312-21. PMID: 16129848.
      Citations: 116     Fields:    Translation:HumansCellsCTClinical Trials
    46. Ruteshouser EC, Hendrickson BW, Colella S, Krahe R, Pinto L, Huff V. Genome-wide loss of heterozygosity analysis of WT1-wild-type and WT1-mutant Wilms tumors. Genes Chromosomes Cancer. 2005 Jun; 43(2):172-80. PMID: 15761866.
      Citations: 10     Fields:    Translation:HumansCells
    47. Gao F, Maiti S, Sun G, Ordonez NG, Udtha M, Deng JM, Behringer RR, Huff V. The Wt1+/R394W mouse displays glomerulosclerosis and early-onset renal failure characteristic of human Denys-Drash syndrome. Mol Cell Biol. 2004 Nov; 24(22):9899-910. PMID: 15509792; PMCID: PMC525476.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    48. Ruteshouser EC, Huff V. Familial Wilms tumor. Am J Med Genet C Semin Med Genet. 2004 Aug 15; 129C(1):29-34. PMID: 15264270.
      Citations: 13     Fields:    Translation:Humans
    49. Royer-Pokora B, Beier M, Henzler M, Alam R, Weirich A, Huff V, Schumacher V. Twenty-four new cases of WT1 germline mutations and review of the literature: genotype/phenotype correlations for Wilms tumor development. Am J Med Genet A. 2004 Jun 15; 127A(3):249-57. PMID: 15150775.
      Citations: 53     Fields:    Translation:Humans
    50. Anderson CE, Punnett HH, Huff V, de Chadar?vian JP. Characterization of a Wilms tumor in a 9-year-old girl with trisomy 18. Am J Med Genet A. 2003 Aug 15; 121A(1):52-5. PMID: 12900902.
      Citations: 8     Fields:    Translation:HumansCells
    51. Udtha M, Lee SJ, Alam R, Coombes K, Huff V. Upregulation of c-MYC in WT1-mutant tumors: assessment of WT1 putative transcriptional targets using cDNA microarray expression profiling of genetically defined Wilms' tumors. Oncogene. 2003 Jun 12; 22(24):3821-6. PMID: 12802290.
      Citations: 12     Fields:    Translation:HumansCells
    52. Green DM, Breslow NE, Beckwith JB, Ritchey ML, Shamberger RC, Haase GM, D'Angio GJ, Perlman E, Donaldson M, Grundy PE, Weetman R, Coppes MJ, Malogolowkin M, Shearer P, Coccia P, Kletzel M, Thomas PR, Macklis R, Tomlinson G, Huff V, Newbury R, Weeks D. Treatment with nephrectomy only for small, stage I/favorable histology Wilms' tumor: a report from the National Wilms' Tumor Study Group. J Clin Oncol. 2001 Sep 01; 19(17):3719-24. PMID: 11533093.
      Citations: 38     Fields:    Translation:HumansCTClinical Trials
    53. Ruteshouser EC, Ashworth LK, Huff V. Absence of PPP2R1A mutations in Wilms tumor. Oncogene. 2001 Apr 12; 20(16):2050-4. PMID: 11360189.
      Citations: 4     Fields:    Translation:Humans
    54. Dharnidharka VR, Ruteshouser EC, Rosen S, Kozakewich H, Harris HW, Herrin JT, Huff V. Pulmonary dysplasia, Denys-Drash syndrome and Wilms tumor 1 gene mutation in twins. Pediatr Nephrol. 2001 Mar; 16(3):227-31. PMID: 11322369.
      Citations: 8     Fields:    Translation:Humans
    55. Maiti S, Alam R, Amos CI, Huff V. Frequent association of beta-catenin and WT1 mutations in Wilms tumors. Cancer Res. 2000 Nov 15; 60(22):6288-92. PMID: 11103785.
      Citations: 78     Fields:    Translation:HumansCells
    56. Hussong JW, Perkins SL, Huff V, McDonald JM, Pysher TJ, Beckwith JB, Coffin CM. Familial Wilms' tumor with neural elements: characterization by histology, immunohistochemistry, and genetic analysis. Pediatr Dev Pathol. 2000 Nov-Dec; 3(6):561-7. PMID: 11000334.
      Citations: 3     Fields:    Translation:HumansCells
    57. Chao LY, Huff V, Strong LC, Saunders GF. Mutation in the PAX6 gene in twenty patients with aniridia. Hum Mutat. 2000; 15(4):332-9. PMID: 10737978.
      Citations: 14     Fields:    Translation:HumansCells
    58. el-Naggar AK, Lai S, Tucker SA, Clayman GL, Goepfert H, Hong WK, Huff V. Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinoma. Oncogene. 1999 Nov 25; 18(50):7063-9. PMID: 10597307.
      Citations: 16     Fields:    Translation:HumansCells
    59. Huff V. Wilms tumor genetics. Am J Med Genet. 1998 Oct 02; 79(4):260-7. PMID: 9781905.
      Citations: 35     Fields:    Translation:Humans
    60. McDonald JM, Douglass EC, Fisher R, Geiser CF, Krill CE, Strong LC, Virshup D, Huff V. Linkage of familial Wilms' tumor predisposition to chromosome 19 and a two-locus model for the etiology of familial tumors. Cancer Res. 1998 Apr 01; 58(7):1387-90. PMID: 9537236.
      Citations: 19     Fields:    Translation:HumansCells
    61. Huff V, Amos CI, Douglass EC, Fisher R, Geiser CF, Krill CE, Li FP, Strong LC, McDonald JM. Evidence for genetic heterogeneity in familial Wilms' tumor. Cancer Res. 1997 May 15; 57(10):1859-62. PMID: 9157975.
      Citations: 4     Fields:    Translation:HumansCells
    62. Huff V. Genotype/phenotype correlations in Wilms' tumor. Med Pediatr Oncol. 1996 Nov; 27(5):408-14. PMID: 8827067.
      Citations: 11     Fields:    Translation:HumansCells
    63. Gunning KB, Cohn SL, Tomlinson GE, Strong LC, Huff V. Analysis of possible WT1 RNA processing in primary Wilms tumors. Oncogene. 1996 Sep 19; 13(6):1179-85. PMID: 8808692.
      Citations: 3     Fields:    Translation:HumansCells
    64. El-Naggar AK, Hurr K, Huff V, Clayman GL, Luna MA, Batsakis JG. Microsatellite instability in preinvasive and invasive head and neck squamous carcinoma. Am J Pathol. 1996 Jun; 148(6):2067-72. PMID: 8669490; PMCID: PMC1861652.
      Citations: 11     Fields:    Translation:HumansCells
    65. El-Naggar AK, Hurr K, Huff V, Luna MA, Goepfert H, Batsakis JG. Allelic loss and replication errors at microsatellite loci on chromosome 11p in head and neck squamous carcinoma: association with aggressive biological features. Clin Cancer Res. 1996 May; 2(5):903-7. PMID: 9816248.
      Citations: 2     Fields:    Translation:HumansCells
    66. Priest JR, Watterson J, Strong L, Huff V, Woods WG, Byrd RL, Friend SH, Newsham I, Amylon MD, Pappo A, Mahoney DH, Langston C, Heyn R, Kohut G, Freyer DR, Bostrom B, Richardson MS, Barredo J, Dehner LP. Pleuropulmonary blastoma: a marker for familial disease. J Pediatr. 1996 Feb; 128(2):220-4. PMID: 8636815.
      Citations: 49     Fields:    Translation:HumansCells
    67. Mars WM, Patmasiriwat P, Maity T, Huff V, Weil MM, Saunders GF. Inheritance of unequal numbers of the genes encoding the human neutrophil defensins HP-1 and HP-3. J Biol Chem. 1995 Dec 22; 270(51):30371-6. PMID: 8530462.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    68. el-Naggar AK, Hurr K, Batsakis JG, Luna MA, Goepfert H, Huff V. Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma. Cancer Res. 1995 Jun 15; 55(12):2656-9. PMID: 7780981.
      Citations: 26     Fields:    Translation:HumansCells
    69. Heath B, Hill VM, Jackson CE, Zarbo RJ, Mallette LE, Chew SL, Besser GM, Thakker RV, Huff V, Szab? J, et al. Hereditary hyperparathyroidism-jaw tumor syndrome: the endocrine tumor gene HRPT2 maps to chromosome 1q21-q31. Am J Hum Genet. 1995 Apr; 56(4):944-50. PMID: 7717405; PMCID: PMC1801214.
      Citations: 46     Fields:    Translation:HumansCells
    70. Huff V, Jaffe N, Saunders GF, Strong LC, Villalba F, Ruteshouser EC. WT1 exon 1 deletion/insertion mutations in Wilms tumor patients, associated with di- and trinucleotide repeats and deletion hotspot consensus sequences. Am J Hum Genet. 1995 Jan; 56(1):84-90. PMID: 7825606; PMCID: PMC1801329.
      Citations: 11     Fields:    Translation:HumansCells
    71. Huff V. Parental origin of WT1 mutations and mental retardation in WAGR syndrome. Nat Genet. 1994 Sep; 8(1):13-4. PMID: 7987386.
      Citations:    Fields:    Translation:HumansCells
    72. Huff V, Joubert I, Badzioch M, Saunders G, Strong L, Perbal B, Martinerie C. Structural analysis of the human nov proto-oncogene and expression in Wilms tumor. Oncogene. 1994 Sep; 9(9):2729-32. PMID: 7520150.
      Citations: 20     Fields:    Translation:HumansCells
    73. Grundy PE, Telzerow PE, Breslow N, Moksness J, Huff V, Paterson MC. Loss of heterozygosity for chromosomes 16q and 1p in Wilms' tumors predicts an adverse outcome. Cancer Res. 1994 May 01; 54(9):2331-3. PMID: 8162576.
      Citations: 48     Fields:    Translation:HumansCells
    74. Fraizer GC, Wu YJ, Hewitt SM, Maity T, Ton CC, Huff V, Saunders GF. Transcriptional regulation of the human Wilms' tumor gene (WT1). Cell type-specific enhancer and promiscuous promoter. J Biol Chem. 1994 Mar 25; 269(12):8892-900. PMID: 8132626.
      Citations: 24     Fields:    Translation:HumansCells
    75. Huff V, Saunders GF. Wilms tumor genes. Biochim Biophys Acta. 1993 Dec 23; 1155(3):295-306. PMID: 8268188.
      Citations: 9     Fields:    Translation:Humans
    76. Coppes MJ, Huff V, Pelletier J. Denys-Drash syndrome: relating a clinical disorder to genetic alterations in the tumor suppressor gene WT1. J Pediatr. 1993 Nov; 123(5):673-8. PMID: 8229473.
      Citations: 15     Fields:    Translation:Humans
    77. Chao LY, Huff V, Tomlinson G, Riccardi VM, Strong LC, Saunders GF. Genetic mosaicism in normal tissues of Wilms' tumour patients. Nat Genet. 1993 Feb; 3(2):127-31. PMID: 8388768.
      Citations: 15     Fields:    Translation:HumansCells
    78. Huff V, Reeve AE, Leppert M, Strong LC, Douglass EC, Geiser CF, Li FP, Meadows A, Callen DF, Lenoir G, et al. Nonlinkage of 16q markers to familial predisposition to Wilms' tumor. Cancer Res. 1992 Nov 01; 52(21):6117-20. PMID: 1356625.
      Citations: 7     Fields:    Translation:HumansCells
    79. Miwa H, Tomlinson GE, Timmons CF, Huff V, Cohn SL, Strong LC, Saunders GF. RNA expression of the WT1 gene in Wilms' tumors in relation to histology. J Natl Cancer Inst. 1992 Feb 05; 84(3):181-7. PMID: 1311774.
      Citations: 9     Fields:    Translation:Humans
    80. Haddad FS. Re: Familial renal cell carcinoma: hereditary or coincidental? J Urol. 1991 Jul; 146(1):168. PMID: 2056584.
      Citations:    Fields:    Translation:Humans
    81. Huff V, Miwa H, Haber DA, Call KM, Housman D, Strong LC, Saunders GF. Evidence for WT1 as a Wilms tumor (WT) gene: intragenic germinal deletion in bilateral WT. Am J Hum Genet. 1991 May; 48(5):997-1003. PMID: 1673293; PMCID: PMC1683037.
      Citations: 45     Fields:    Translation:HumansCells
    82. Ton CC, Huff V, Call KM, Cohn S, Strong LC, Housman DE, Saunders GF. Smallest region of overlap in Wilms tumor deletions uniquely implicates an 11p13 zinc finger gene as the disease locus. Genomics. 1991 May; 10(1):293-7. PMID: 1646159.
      Citations: 14     Fields:    Translation:HumansCells
    83. Levinson AK, Johnson DE, Strong LC, Pathak S, Huff V, Saunders GF. Familial renal cell carcinoma: hereditary or coincidental? J Urol. 1990 Oct; 144(4):849-51. PMID: 2398557.
      Citations:    Fields:    Translation:Humans
    84. Huff V, Meadows A, Riccardi VM, Strong LC, Saunders GF. Parental origin of de novo constitutional deletions of chromosomal band 11p13. Am J Hum Genet. 1990 Jul; 47(1):155-60. PMID: 1971994; PMCID: PMC1683741.
      Citations: 15     Fields:    Translation:HumansCells
    85. Ton CC, Huff V, Weil MM, Strong LC, Saunders GF. A BglII RFLP detected by the probe JA8-1 at human chromosome band 11p13 (D11S417). Nucleic Acids Res. 1990 Feb 25; 18(4):1084. PMID: 1969141; PMCID: PMC330401.
      Citations: 1     Fields:    Translation:HumansCells
    86. Weil MM, Huff V, Compton DA, Strong LC, Saunders GF. An XmnI polymorphism detected by a human genomic clone from chromosomal band 11p13 [D11S416]. Nucleic Acids Res. 1990 Feb 11; 18(3):689. PMID: 1968626; PMCID: PMC333512.
      Citations:    Fields:    Translation:HumansCells
    87. Huff V, Compton DA, Strong LC, Saunders GF. A panel of restriction fragment length polymorphisms for chromosomal band 11p13. Hum Genet. 1990 Feb; 84(3):253-7. PMID: 1968033.
      Citations: 5     Fields:    Translation:HumansCells
    88. Huff V, Compton DA, Chao LY, Strong LC, Geiser CF, Saunders GF. Lack of linkage of familial Wilms' tumour to chromosomal band 11p13. Nature. 1988 Nov 24; 336(6197):377-8. PMID: 2848200.
      Citations: 39     Fields:    Translation:HumansCells
    89. Huff V, Cai W, Glorioso JC, Levine M. The carboxy-terminal 41 amino acids of herpes simplex virus type 1 glycoprotein B are not essential for production of infectious virus particles. J Virol. 1988 Nov; 62(11):4403-6. PMID: 2845151; PMCID: PMC253883.
      Citations: 12     Fields:    Translation:AnimalsCells
    90. Huff V, Compton D, Lewis W, Jones C, Strong LC, Saunders GF. An EcoRI polymorphism associated with a human genomic clone from band 11p13. Nucleic Acids Res. 1987 Sep 25; 15(18):7651. PMID: 2889190; PMCID: PMC306284.
      Citations: 3     Fields:    Translation:HumansCells
    91. DuFrain RJ, Littlefield LG, Morrison WD, Huff VD, Hutton D. Evaluation of chemically induced cytogenetic lesions in rabbit oocytes. III. A postimplantation analysis of streptonigrin effects. Mutat Res. 1984 Jun; 127(1):73-9. PMID: 6727905.
      Citations: 1     Fields:    Translation:AnimalsCells
    92. Wt1 directs the lineage specification of sertoli and granulosa cells by repressing Sf1 expression. Development (Cambridge). 144:44-53.
    93. Abrogation of WT1 function in Wilms' tumors. International Journal of Pediatric Hematology/Oncology. 5:45-46.
    94. Blotting assays. Cancer Bulletin. 47:268-271.
    95. Erratum to Recurrent DGCR8, DROSHA, and SIX Homeodomain Mutations in Favorable Histology Wilms Tumors [Cancer Cell., 27, 286-297 (2015)] DOI. Cancer Cell. 27:426.
    96. Clinical Outcome and Biological Predictors of Relapse After Nephrectomy Only for Very Low-risk Wilms Tumor. Annals of Surgery.
    97. Characterization of the inflammatory microenvironment and identification of potential therapeutic targets in wilms tumors. Translational Oncology. 7:484-492.
    98. MLLT1 YEATS domain mutations in clinically distinctive Favourable Histology Wilms tumours. Nature Communications. 6.
    99. Identification of germline DICER1 mutations and loss of heterozygosity in familial Wilms tumour. Journal of Medical Genetics. 53:385-388.
    100. Reply to B. Royer-Pokora et al. Journal of Clinical Oncology. 29.
    101. Nephron Progenitor But Not Stromal Progenitor Cells Give Rise to Wilms Tumors in Mouse Models with β-Catenin Activation or Wt1 Ablation and Igf2 Upregulation. Neoplasia (United States). 18:71-81.
    102. Significance of TP53 mutation in Wilms tumors with diffuse anaplasia. Clinical Cancer Research. 22:5582-5591.
    103. Inheritance and functionality of Wilms' tumor genes. Cancer Bulletin. 46:254-259.
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