JAGANNADHA KSASTRYJAGANNADHA K SASTRY8499SASTRY, JAGANNADHA KProfessorprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson17291642Manuri PR, Nehete B, Nehete PN, Reisenauer R, Wardell S, Courtney AN, Gambhira R, Lomada D, Chopra AK, Sastry KJVaccineIntranasal immunization with synthetic peptides corresponding to the E6 and E7 oncoproteins of human papillomavirus type 16 induces systemic and mucosal cellular immune responses and tumor protection. Vaccine. 2007 Apr 30; 25(17):3302-10.Vaccine2007-01-24T00:00:002007Intranasal immunization with synthetic peptides corresponding to the E6 and E7 oncoproteins of human papillomavirus type 16 induces systemic and mucosal cellular immune responses and tumor protection.19200815Thapa P, Zhang G, Xia C, Gelbard A, Overwijk WW, Liu C, Hwu P, Chang DZ, Courtney A, Sastry JK, Wang PG, Li C, Zhou DVaccineNanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy. Vaccine. 2009 May 26; 27(25-26):3484-8.Vaccine2009-02-05T00:00:002009Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy.19200849Courtney AN, Nehete PN, Nehete BP, Thapa P, Zhou D, Sastry KJVaccineAlpha-galactosylceramide is an effective mucosal adjuvant for repeated intranasal or oral delivery of HIV peptide antigens. Vaccine. 2009 May 26; 27(25-26):3335-41.Vaccine2009-02-05T00:00:002009Alpha-galactosylceramide is an effective mucosal adjuvant for repeated intranasal or oral delivery of HIV peptide antigens.19805372Fontenot D, He H, Hanabuchi S, Nehete PN, Zhang M, Chang M, Nehete B, Wang YH, Wang YH, Ma ZM, Lee HC, Ziegler SF, Courtney AN, Miller CJ, Sun SC, Liu YJ, Sastry KJProceedings of the National Academy of Sciences of the United States of AmericaTSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells. Proc Natl Acad Sci U S A. 2009 Sep 29; 106(39):16776-81.Proc Natl Acad Sci U S A2009-09-21T00:00:002009TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells.20414189He H, Courtney AN, Wieder E, Sastry KJJournal of visualized experiments : JoVEMulticolor flow cytometry analyses of cellular immune response in rhesus macaques. J Vis Exp. 2010 Apr 22; (38).J Vis Exp2010-04-22T00:00:002010Multicolor flow cytometry analyses of cellular immune response in rhesus macaques.21818755Courtney AN, Thapa P, Singh S, Wishahy AM, Zhou D, Sastry JEuropean journal of immunologyIntranasal but not intravenous delivery of the adjuvant a-galactosylceramide permits repeated stimulation of natural killer T cells in the lung. Eur J Immunol. 2011 Nov; 41(11):3312-22.Eur J Immunol2011-09-19T00:00:002011Intranasal but not intravenous delivery of the adjuvant a-galactosylceramide permits repeated stimulation of natural killer T cells in the lung.7455 Fannin StHouston77054-1901TXAuthorship 1642381Authorship 1648413Authorship 1662775Authorship 1670953Authorship 1680065Authorship 1680096Authorship 1711697Authorship 1732134Authorship 1745407Authorship 1753171Authorship 17720510Authorship 1806577Authorship 1826476Authorship 1830336Authorship 18346517Authorship 18444510Authorship 1850057Authorship 1858454Authorship 1858687Authorship 1883804Authorship 1898666Authorship 1920129Authorship 19205511Authorship 1929258Authorship 19438656401288Sastry KJ, Srivastava OP, Millet J, FitzJames PC, Aronson AIJournal of bacteriologyCharacterization of Bacillus subtilis mutants with a temperature-sensitive intracellular protease. J Bacteriol. 1983 Jan; 153(1):511-9.J Bacteriol1983-01-01T00:00:001983Characterization of Bacillus subtilis mutants with a temperature-sensitive intracellular protease.7576033Nehete PN, Arlinghaus RB, Sastry KJViral immunologyUse of helper T cell-inducing peptides from conserved regions in HIV-1 env in a noncovalent mixture with a CTL-inducing V3-loop peptide for in vivo induction of long-lasting systemic CTL response. Viral Immunol. 1994; 7(4):189-97.Viral Immunol1994-01-01T00:00:001994Use of helper T cell-inducing peptides from conserved regions in HIV-1 env in a noncovalent mixture with a CTL-inducing V3-loop peptide for in vivo induction of long-lasting systemic CTL response.8690775Nehete PN, Johnson PC, Schapiro SJ, Arlinghaus RB, Sastry KJJournal of clinical immunologyCross-reactive T-cell proliferative responses to V3 peptides corresponding to different geographical HIV-1 isolates in HIV-seropositive individuals. J Clin Immunol. 1996 Mar; 16(2):115-24.J Clin Immunol1996-03-01T00:00:001996Cross-reactive T-cell proliferative responses to V3 peptides corresponding to different geographical HIV-1 isolates in HIV-seropositive individuals.8902081Casement KS, Arlinghaus KB, Sastry KJAIDS (London, England)Cytotoxic T-lymphocyte response induced by a V3 loop synthetic peptide from an African HIV-1 isolate is cross-reactive against HIV-1 strains from North America/Europe region. AIDS. 1996 Oct; 10(12):1440-1.AIDS1996-10-01T00:00:001996Cytotoxic T-lymphocyte response induced by a V3 loop synthetic peptide from an African HIV-1 isolate is cross-reactive against HIV-1 strains from North America/Europe region.9918403Nehete PN, Lewis DE, Tang DN, Pollack MS, Sastry KJViral immunologyPresence of HLA-C-restricted cytotoxic T-lymphocyte responses in long-term nonprogressors infected with human immunodeficiency virus. Viral Immunol. 1998; 11(3):119-29.Viral Immunol1998-01-01T00:00:001998Presence of HLA-C-restricted cytotoxic T-lymphocyte responses in long-term nonprogressors infected with human immunodeficiency virus.9918406Nehete PN, Schapiro SJ, Johnson PC, Murthy KK, Satterfield WC, Sastry KJViral immunologyA synthetic peptide from the first conserved region in the envelope protein gp160 is a strong T-cell epitope in HIV-infected chimpanzees and humans. Viral Immunol. 1998; 11(3):147-58.Viral Immunol1998-01-01T00:00:001998A synthetic peptide from the first conserved region in the envelope protein gp160 is a strong T-cell epitope in HIV-infected chimpanzees and humans.12406507Nehete PN, Vela EM, Hossain MM, Sarkar AK, Yahi N, Fantini J, Sastry KJAntiviral researchA post-CD4-binding step involving interaction of the V3 region of viral gp120 with host cell surface glycosphingolipids is common to entry and infection by diverse HIV-1 strains. Antiviral Res. 2002 Dec; 56(3):233-51.Antiviral Res2002-12-01T00:00:002002A post-CD4-binding step involving interaction of the V3 region of viral gp120 with host cell surface glycosphingolipids is common to entry and infection by diverse HIV-1 strains.12733599Keeney TS, Nomura LE, Maecker HT, Sastry KJJournal of medical primatologyFlow cytometric analysis of macaque whole blood for antigen-specific intracellular cytokine production by T lymphocytes. J Med Primatol. 2003 Feb; 32(1):23-30.J Med Primatol2003-02-01T00:00:002003Flow cytometric analysis of macaque whole blood for antigen-specific intracellular cytokine production by T lymphocytes.15937350Sastry KJ, Nehete PN, Nehete BMethods in molecular biology (Clifton, N.J.)Improving the sensitivity of the ELISPOT analyses of antigen-specific cellular immune responses in rhesus macaques. Methods Mol Biol. 2005; 302:153-66.Methods Mol Biol2005-01-01T00:00:002005Improving the sensitivity of the ELISPOT analyses of antigen-specific cellular immune responses in rhesus macaques.16214207Hamada K, Sakaue M, Sarkar A, Buchl S, Satterfield W, Keeling M, Sastry J, Roth JA, Follen MGynecologic oncologyImmune responses to repetitive adenovirus-mediated gene transfer and restoration of gene expression by cyclophosphamide or etoposide. Gynecol Oncol. 2005 Dec; 99(3 Suppl 1):S177-86.Gynecol Oncol2005-10-07T00:00:002005Immune responses to repetitive adenovirus-mediated gene transfer and restoration of gene expression by cyclophosphamide or etoposide.18632641Wang-Johanning F, Radvanyi L, Rycaj K, Plummer JB, Yan P, Sastry KJ, Piyathilake CJ, Hunt KK, Johanning GLCancer researchHuman endogenous retrovirus K triggers an antigen-specific immune response in breast cancer patients. Cancer Res. 2008 Jul 15; 68(14):5869-77.Cancer Res2008-07-15T00:00:002008Human endogenous retrovirus K triggers an antigen-specific immune response in breast cancer patients.20454526Qin H, Nehete PN, He H, Nehete B, Buchl S, Cha SC, Sastry JK, Kwak LWJournal of biomedicine & biotechnologyPrime-boost vaccination using chemokine-fused gp120 DNA and HIV envelope peptides activates both immediate and long-term memory cellular responses in rhesus macaques. J Biomed Biotechnol. 2010; 2010:860160.J Biomed Biotechnol2010-05-05T00:00:002010Prime-boost vaccination using chemokine-fused gp120 DNA and HIV envelope peptides activates both immediate and long-term memory cellular responses in rhesus macaques.23127567Singh S, Shenoy S, Nehete PN, Yang P, Nehete B, Fontenot D, Yang G, Newman RA, Sastry KJFitoterapiaNerium oleander derived cardiac glycoside oleandrin is a novel inhibitor of HIV infectivity. Fitoterapia. 2013 Jan; 84:32-9.Fitoterapia2012-11-02T00:00:002012Nerium oleander derived cardiac glycoside oleandrin is a novel inhibitor of HIV infectivity.24282512Nehete PN, Hanley PW, Nehete BP, Yang G, Ruiz JC, Williams L, Abee CR, Sastry KJPloS onePhenotypic and functional characterization of lymphocytes from different age groups of Bolivian squirrel monkeys (Saimiri boliviensis boliviensis). PLoS One. 2013; 8(11):e79836.PLoS One2013-11-25T00:00:002013Phenotypic and functional characterization of lymphocytes from different age groups of Bolivian squirrel monkeys (Saimiri boliviensis boliviensis).24599269Singh S, Yang G, Schluns KS, Anthony SM, Sastry KJPloS oneSublingual vaccination induces mucosal and systemic adaptive immunity for protection against lung tumor challenge. PLoS One. 2014; 9(3):e90001.PLoS One2014-03-05T00:00:002014Sublingual vaccination induces mucosal and systemic adaptive immunity for protection against lung tumor challenge.Palliative Care & Rehabilitation MedicineRadiation OncologyVeterinary Medicine & SurgeryVeterinary SciencesMD Anderson2.266020.00553499418research areas4.276750.01737736coauthor of45.47518.0651860similar to1184selected publicationsPEIYINGYANGPEIYING YANG8795YANG, PEIYINGAssociate ProfessorPRAMOD NNEHETEPRAMOD N NEHETE8630NEHETE, PRAMOD NAssociate ProfessorANN HKLOPPANN H KLOPP9213KLOPP, ANN HAssociate ProfessorAuthorship 2123451Authorship 2124071Authorship 2142291Authorship 2148701Authorship 2154154Authorship 2157822Authorship 2166048Authorship 2205464Authorship 2218203Authorship 2220577Authorship 2227506Authorship 223853Authorship 2253635Authorship 22694042243081Sastry KJ, Reddy HR, Pandita R, Totpal K, Aggarwal BBThe Journal of biological chemistryHIV-1 tat gene induces tumor necrosis factor-beta (lymphotoxin) in a human B-lymphoblastoid cell line. J Biol Chem. 1990 Nov 25; 265(33):20091-3.J Biol Chem1990-11-25T00:00:001990HIV-1 tat gene induces tumor necrosis factor-beta (lymphotoxin) in a human B-lymphoblastoid cell line.2258362Sastry KJ, Arlinghaus RBHematologic pathologyA novel HIV vaccine strategy. Hematol Pathol. 1990; 4(3):157-9.Hematol Pathol1990-01-01T00:00:001990A novel HIV vaccine strategy.2835956Sastry KJ, Huang C, Chan TSBiochemical geneticsAdenosine kinase deficiency in tritiated deoxyadenosine-resistant mouse S49 lymphoma cell lines. Biochem Genet. 1987 Dec; 25(11-12):765-77.Biochem Genet1987-12-01T00:00:001987Adenosine kinase deficiency in tritiated deoxyadenosine-resistant mouse S49 lymphoma cell lines.6790385Sastry KJ, Strnadov? M, Chaloupka JFolia microbiologicaSynthesis of exocellular proteins during the exponential and stationary phase of growth of Bacillus megaterium. Folia Microbiol (Praha). 1981; 26(2):73-7.Folia Microbiol (Praha)1981-01-01T00:00:001981Synthesis of exocellular proteins during the exponential and stationary phase of growth of Bacillus megaterium.7720083Nehete PN, Casement KS, Arlinghaus RB, Sastry KJCellular immunologyStudies on in vivo induction of HIV-1 envelope-specific cytotoxic T lymphocytes by synthetic peptides from the V3 loop region of HIV-1 IIIB gp 120. Cell Immunol. 1995 Feb; 160(2):217-23.Cell Immunol1995-02-01T00:00:001995Studies on in vivo induction of HIV-1 envelope-specific cytotoxic T lymphocytes by synthetic peptides from the V3 loop region of HIV-1 IIIB gp 120.9519777Oka T, Sastry KJ, Nehete P, Schapiro SJ, Guo JQ, Talpaz M, Arlinghaus RBLeukemiaEvidence for specific immune response against P210 BCR-ABL in long-term remission CML patients treated with interferon. Leukemia. 1998 Feb; 12(2):155-63.Leukemia1998-02-01T00:00:001998Evidence for specific immune response against P210 BCR-ABL in long-term remission CML patients treated with interferon.10359207Sarkar AK, Mitchell MF, Hamada K, Buchl SJ, Satterfield WC, Schapiro SJ, Keeling ME, Sastry KJCancer gene therapyEvaluation of cellular immune responses in rhesus monkeys subjected to adenovirus-mediated gene transfer into the cervix. Cancer Gene Ther. 1999 May-Jun; 6(3):220-7.Cancer Gene Ther1999-05-01T00:00:001999Evaluation of cellular immune responses in rhesus monkeys subjected to adenovirus-mediated gene transfer into the cervix.15017035Starost MF, Hill LR, Nehete PN, Sastry KJVeterinary pathologyExtramedullary hematopoiesis in the mandibular lymph node of simian-human immunodeficiency virus-infected rhesus monkeys (Macaca mulatta): a report of three cases. Vet Pathol. 2004 Mar; 41(2):186-90.Vet Pathol2004-03-01T00:00:002004Extramedullary hematopoiesis in the mandibular lymph node of simian-human immunodeficiency virus-infected rhesus monkeys (Macaca mulatta): a report of three cases.15530705Lomada D, Gambhira R, Nehete PN, Guhad FA, Chopra AK, Peterson JW, Sastry KJVaccineA two-codon mutant of cholera toxin lacking ADP-ribosylating activity functions as an effective adjuvant for eliciting mucosal and systemic cellular immune responses to peptide antigens. Vaccine. 2004 Dec 09; 23(4):555-65.Vaccine2004-12-09T00:00:002004A two-codon mutant of cholera toxin lacking ADP-ribosylating activity functions as an effective adjuvant for eliciting mucosal and systemic cellular immune responses to peptide antigens.15755586Nehete PN, Nehete BP, Manuri P, Hill L, Palmer JL, Sastry KJVaccineProtection by dendritic cells-based HIV synthetic peptide cocktail vaccine: preclinical studies in the SHIV-rhesus model. Vaccine. 2005 Mar 18; 23(17-18):2154-9.Vaccine2005-03-18T00:00:002005Protection by dendritic cells-based HIV synthetic peptide cocktail vaccine: preclinical studies in the SHIV-rhesus model.16501119de Parseval A, Grant CK, Sastry KJ, Elder JHJournal of virologySequential CD134-CXCR4 interactions in feline immunodeficiency virus (FIV): soluble CD134 activates FIV Env for CXCR4-dependent entry and reveals a cryptic neutralization epitope. J Virol. 2006 Mar; 80(6):3088-91.J Virol2006-03-01T00:00:002006Sequential CD134-CXCR4 interactions in feline immunodeficiency virus (FIV): soluble CD134 activates FIV Env for CXCR4-dependent entry and reveals a cryptic neutralization epitope.17320923Fontenot D, Jones JK, Hossain MM, Nehete PN, Vela EM, Dwyer VA, Jagannadha Sastry KVirologyCritical role of Arg59 in the high-affinity gp120-binding region of CD4 for human immunodeficiency virus type 1 infection. Virology. 2007 Jun 20; 363(1):69-78.Virology2007-02-23T00:00:002007Critical role of Arg59 in the high-affinity gp120-binding region of CD4 for human immunodeficiency virus type 1 infection.17919453Fontenot DR, den Hollander P, Vela EM, Newman R, Sastry JK, Kumar RBiochemical and biophysical research communicationsDynein light chain 1 peptide inhibits human immunodeficiency virus infection in eukaryotic cells. Biochem Biophys Res Commun. 2007 Nov 30; 363(4):901-7.Biochem Biophys Res Commun2007-09-21T00:00:002007Dynein light chain 1 peptide inhibits human immunodeficiency virus infection in eukaryotic cells.18596086Sundstrom M, White RL, de Parseval A, Sastry KJ, Morris G, Grant CK, Elder JHJournal of virologyMapping of the CXCR4 binding site within variable region 3 of the feline immunodeficiency virus surface glycoprotein. J Virol. 2008 Sep; 82(18):9134-42.J Virol2008-07-02T00:00:002008Mapping of the CXCR4 binding site within variable region 3 of the feline immunodeficiency virus surface glycoprotein.Authorship 2356441Authorship 2368991Authorship 2377021Authorship 2377161Authorship 2388014Authorship 2389403Authorship 2391461Authorship 2391643Authorship 2427348Authorship 2448558Authorship 2449824Authorship 2461655Authorship 2476334Authorship 2508338Authorship 2556927Authorship 26056061316670Sastry KJ, Nehete PN, Venkatnarayanan S, Morkowski J, Platsoucas CD, Arlinghaus RBVirologyRapid in vivo induction of HIV-specific CD8+ cytotoxic T lymphocytes by a 15-amino acid unmodified free peptide from the immunodominant V3-loop of GP120. Virology. 1992 Jun; 188(2):502-9.Virology1992-06-01T00:00:001992Rapid in vivo induction of HIV-specific CD8+ cytotoxic T lymphocytes by a 15-amino acid unmodified free peptide from the immunodominant V3-loop of GP120.1372082Sastry JK, Nehete PN, Khan S, Nowak BJ, Plunkett W, Arlinghaus RB, Farquhar DMolecular pharmacologyMembrane-permeable dideoxyuridine 5'-monophosphate analogue inhibits human immunodeficiency virus infection. Mol Pharmacol. 1992 Mar; 41(3):441-5.Mol Pharmacol1992-03-01T00:00:001992Membrane-permeable dideoxyuridine 5'-monophosphate analogue inhibits human immunodeficiency virus infection.1715718Sastry KJ, Arlinghaus RBAIDS (London, England)Identification of T-cell epitopes without B-cell activity in the first and second conserved regions of the HIV Env protein. AIDS. 1991 Jun; 5(6):699-707.AIDS1991-06-01T00:00:001991Identification of T-cell epitopes without B-cell activity in the first and second conserved regions of the HIV Env protein.4062946Sastry KJ, Chan TS, Rodriguez LVBiochemical and biophysical research communicationsSelective overproduction of human dihydrofolate reductase in a methotrexate-resistant human-mouse somatic cell hybrid. Biochem Biophys Res Commun. 1985 Oct 30; 132(2):795-803.Biochem Biophys Res Commun1985-10-30T00:00:001985Selective overproduction of human dihydrofolate reductase in a methotrexate-resistant human-mouse somatic cell hybrid.7645219Casement KS, Nehete PN, Arlinghaus RB, Sastry KJVirologyCross-reactive cytotoxic T lymphocytes induced by V3 loop synthetic peptides from different strains of human immunodeficiency virus type 1. Virology. 1995 Aug 01; 211(1):261-7.Virology1995-08-01T00:00:001995Cross-reactive cytotoxic T lymphocytes induced by V3 loop synthetic peptides from different strains of human immunodeficiency virus type 1.7692087Nehete PN, Arlinghaus RB, Sastry KJJournal of virologyInhibition of human immunodeficiency virus type 1 infection and syncytium formation in human cells by V3 loop synthetic peptides from gp120. J Virol. 1993 Nov; 67(11):6841-6.J Virol1993-11-01T00:00:001993Inhibition of human immunodeficiency virus type 1 infection and syncytium formation in human cells by V3 loop synthetic peptides from gp120.8623835Mitchell MF, Hamada K, Sastry KJ, Sarkar A, Tortolero-Luna G, Wharton JT, Roth JAAmerican journal of obstetrics and gynecologyTransgene expression in the rhesus cervix mediated by an adenovirus expressing beta-galactosidase. Am J Obstet Gynecol. 1996 Apr; 174(4):1094-101.Am J Obstet Gynecol1996-04-01T00:00:001996Transgene expression in the rhesus cervix mediated by an adenovirus expressing beta-galactosidase.8760290Sastry KJ, Marin MC, Nehete PN, McConnell K, el-Naggar AK, McDonnell TJOncogeneExpression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells. Oncogene. 1996 Aug 01; 13(3):487-93.Oncogene1996-08-01T00:00:001996Expression of human immunodeficiency virus type I tat results in down-regulation of bcl-2 and induction of apoptosis in hematopoietic cells.11436543Dolbier CL, Cocke RR, Leiferman JA, Steinhardt MA, Schapiro SJ, Nehete PN, Perlman JE, Sastry JJournal of behavioral medicineDifferences in functional immune responses of high vs. low hardy healthy individuals. J Behav Med. 2001 Jun; 24(3):219-29.J Behav Med2001-06-01T00:00:002001Differences in functional immune responses of high vs. low hardy healthy individuals.11738745Nehete PN, Chitta S, Hossain MM, Hill L, Bernacky BJ, Baze W, Arlinghaus RB, Sastry KJVaccineProtection against chronic infection and AIDS by an HIV envelope peptide-cocktail vaccine in a pathogenic SHIV-rhesus model. Vaccine. 2001 Dec 12; 20(5-6):813-25.Vaccine2001-12-12T00:00:002001Protection against chronic infection and AIDS by an HIV envelope peptide-cocktail vaccine in a pathogenic SHIV-rhesus model.12823628Nehete PN, Gambhira R, Nehete BP, Sastry KJJournal of medical primatologyDendritic cells enhance detection of antigen-specific cellular immune responses by lymphocytes from rhesus macaques immunized with an HIV envelope peptide cocktail vaccine. J Med Primatol. 2003 Apr; 32(2):67-73.J Med Primatol2003-04-01T00:00:002003Dendritic cells enhance detection of antigen-specific cellular immune responses by lymphocytes from rhesus macaques immunized with an HIV envelope peptide cocktail vaccine.15061727Hill LR, Nehete PN, Schapiro SJ, Nehete BP, Sastry KJJournal of medical primatologySHIV transmission and susceptibility to re-exposure through social contact following vaccination with an HIV synthetic peptide-cocktail: a case study. J Med Primatol. 2004 Feb; 33(1):10-5.J Med Primatol2004-02-01T00:00:002004SHIV transmission and susceptibility to re-exposure through social contact following vaccination with an HIV synthetic peptide-cocktail: a case study.16188303Sarkar AK, Tortolero-Luna G, Follen M, Sastry KJGynecologic oncologyInverse correlation of cellular immune responses specific to synthetic peptides from the E6 and E7 oncoproteins of HPV-16 with recurrence of cervical intraepithelial neoplasia in a cross-sectional study. Gynecol Oncol. 2005 Dec; 99(3 Suppl 1):S251-61.Gynecol Oncol2005-09-26T00:00:002005Inverse correlation of cellular immune responses specific to synthetic peptides from the E6 and E7 oncoproteins of HPV-16 with recurrence of cervical intraepithelial neoplasia in a cross-sectional study.17920095Nehete PN, Nehete BP, Hill L, Manuri PR, Baladandayuthapani V, Feng L, Simmons J, Sastry KJVirologySelective induction of cell-mediated immunity and protection of rhesus macaques from chronic SHIV(KU2) infection by prophylactic vaccination with a conserved HIV-1 envelope peptide-cocktail. Virology. 2008 Jan 05; 370(1):130-41.Virology2007-10-24T00:00:002007Selective induction of cell-mediated immunity and protection of rhesus macaques from chronic SHIV(KU2) infection by prophylactic vaccination with a conserved HIV-1 envelope peptide-cocktail.21602924He H, Nehete PN, Nehete B, Wieder E, Yang G, Buchl S, Sastry KJPloS oneFunctional impairment of central memory CD4 T cells is a potential early prognostic marker for changing viral load in SHIV-infected rhesus macaques. PLoS One. 2011; 6(5):e19607.PLoS One2011-05-13T00:00:002011Functional impairment of central memory CD4 T cells is a potential early prognostic marker for changing viral load in SHIV-infected rhesus macaques.23612978Wang X, Singh S, Jung HY, Yang G, Jun S, Sastry KJ, Park JIThe Journal of biological chemistryHIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex. J Biol Chem. 2013 May 31; 288(22):15474-80.J Biol Chem2013-04-23T00:00:002013HIV-1 Vpr protein inhibits telomerase activity via the EDD-DDB1-VPRBP E3 ligase complex.Authorship 2642025Authorship 2657627Authorship 26761297662194Nehete PN, Murthy KK, Satterfield WC, Arlinghaus RB, Sastry KJAIDS (London, England)Studies on V3-specific cross-reactive T-cell responses in chimpanzees chronically infected with HIV-1IIIB. AIDS. 1995 Jun; 9(6):567-72.AIDS1995-06-01T00:00:001995Studies on V3-specific cross-reactive T-cell responses in chimpanzees chronically infected with HIV-1IIIB.14603541Follen M, Meyskens FL, Alvarez RD, Walker JL, Bell MC, Storthz KA, Sastry J, Roy K, Richards-Kortum R, Cornelison TLCancerCervical cancer chemoprevention, vaccines, and surrogate endpoint biomarkers. Cancer. 2003 Nov 01; 98(9 Suppl):2044-51.Cancer2003-11-01T00:00:002003Cervical cancer chemoprevention, vaccines, and surrogate endpoint biomarkers.18063450Mercier GT, Nehete PN, Passeri MF, Nehete BN, Weaver EA, Templeton NS, Schluns K, Buchl SS, Sastry KJ, Barry MAVaccineOral immunization of rhesus macaques with adenoviral HIV vaccines using enteric-coated capsules. Vaccine. 2007 Dec 17; 25(52):8687-701.Vaccine2007-11-05T00:00:002007Oral immunization of rhesus macaques with adenoviral HIV vaccines using enteric-coated capsules.Authorship 2762646Authorship 2763645Authorship 27644617856292Sastry KJ, Bender BS, Bell W, Small PA, Arlinghaus RBVaccineEffects of influenza virus-specific cytotoxic T-lymphocyte responses induced by a synthetic nucleoprotein peptide on the survival of mice challenged with a lethal dose of virus. Vaccine. 1994 Nov; 12(14):1281-7.Vaccine1994-11-01T00:00:001994Effects of influenza virus-specific cytotoxic T-lymphocyte responses induced by a synthetic nucleoprotein peptide on the survival of mice challenged with a lethal dose of virus.8471313Nehete PN, Satterfield WC, Matherne CM, Arlinghaus RB, Sastry KJAIDS research and human retrovirusesInduction of human immunodeficiency virus-specific T cell responses in rhesus monkeys by synthetic peptides from gp160. AIDS Res Hum Retroviruses. 1993 Mar; 9(3):235-40.AIDS Res Hum Retroviruses1993-03-01T00:00:001993Induction of human immunodeficiency virus-specific T cell responses in rhesus monkeys by synthetic peptides from gp160.8833270Sarkar AK, Tortolero-Luna G, Nehete PN, Arlinghaus RB, Mitchell MF, Sastry KJViral immunologyStudies on in vivo induction of cytotoxic T lymphocyte responses by synthetic peptides from E6 and E7 oncoproteins of human papillomavirus type 16. Viral Immunol. 1995; 8(3):165-74.Viral Immunol1995-01-01T00:00:001995Studies on in vivo induction of cytotoxic T lymphocyte responses by synthetic peptides from E6 and E7 oncoproteins of human papillomavirus type 16.25048139Singh S, Nehete P, Hanley P, Nehete B, Yang G, He H, Anthony SM, Schluns KS, Sastry KJMethods in molecular biology (Clifton, N.J.)Procedures for mucosal immunization and analyses of cellular immune response to candidate HIV vaccines in murine and nonhuman primate models. Methods Mol Biol. 2014; 1184:417-55.Methods Mol Biol2014-01-01T00:00:002014Procedures for mucosal immunization and analyses of cellular immune response to candidate HIV vaccines in murine and nonhuman primate models.25355873Crosby CM, Nehete P, Sastry KJ, Barry MAJournal of virologyAmplified and persistent immune responses generated by single-cycle replicating adenovirus vaccines. J Virol. 2015 Jan; 89(1):669-75.J Virol2014-10-29T00:00:002014Amplified and persistent immune responses generated by single-cycle replicating adenovirus vaccines.74Professor10Assistant Professor27Clinical Assistant Professor14Associate ProfessorLORRAINE RHILLLORRAINE R HILL11733HILL, LORRAINE RAssociate ProfessorAuthorship 3741903Authorship 374194921732950Hutchison AT, Schmitz JE, Miller CJ, Sastry KJ, Nehete PN, Major AM, Ansari AA, Tatevian N, Lewis DEJournal of medical primatologyIncreased inherent intestinal granzyme B expression may be associated with SIV pathogenesis in Asian non-human primates. J Med Primatol. 2011 Dec; 40(6):414-26.J Med Primatol2011-07-07T00:00:002011Increased inherent intestinal granzyme B expression may be associated with SIV pathogenesis in Asian non-human primates.Authorship 841925Authorship 850219Authorship 853366Authorship 856870Authorship 857112Authorship 857280Authorship 857766Authorship 858393Authorship 859071Authorship 860612Authorship 866474Authorship 868139VaccinesEnhancement of mucosal immunogenicity of viral vectored vaccines by the NKT cell agonist alpha-galactosylceramide as adjuvant. Vaccines. 2:686-706.Enhancement of mucosal immunogenicity of viral vectored vaccines by the NKT cell agonist alpha-galactosylceramide as adjuvantVirusesProtection against mucosal SHIV challenge by peptide and helper-dependent adenovirus vaccines. Viruses. 1:920-938.Protection against mucosal SHIV challenge by peptide and helper-dependent adenovirus vaccinesFederation ProceedingsAmplification of the dyhydrofolate reductase gene in methotrexate-resistant human-mouse somatic cell hybrids. Federation Proceedings. 43.Amplification of the dyhydrofolate reductase gene in methotrexate-resistant human-mouse somatic cell hybridsPLoS Neglected Tropical DiseasesThe Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections. PLoS Neglected Tropical Diseases. 10.The Hygiene Hypothesis and Its Inconvenient Truths about Helminth InfectionsFederation ProceedingsTwo-dimensional gel electrophoretic analysis (2D-PAGE) of selective human dihydrofolate reductase overproduction in a methotrexate resistant human-mouse somatic cell hybrid. Federation Proceedings. 44.Two-dimensional gel electrophoretic analysis (2D-PAGE) of selective human dihydrofolate reductase overproduction in a methotrexate resistant human-mouse somatic cell hybridApplied Animal Behaviour ScienceEffects of dominance status and environmental enrichment on cell-mediated immunity in rhesus macaques. Applied Animal Behaviour Science. 56:319-332.Effects of dominance status and environmental enrichment on cell-mediated immunity in rhesus macaquesCurrent Topics in Peptide and Protein ResearchIn vivo targeting of an HIV synthetic peptide cocktail vaccine to dendritic cells in rhesus macaques to prime antigen-specific cell-mediated immunity. Current Topics in Peptide and Protein Research. 11:37-48.In vivo targeting of an HIV synthetic peptide cocktail vaccine to dendritic cells in rhesus macaques to prime antigen-specific cell-mediated immunityJournal of Visualized ExperimentsMulticolor flow cytometry analyses of cellular immune response in rhesus macaques. Journal of Visualized Experiments. Multicolor flow cytometry analyses of cellular immune response in rhesus macaquesApplied Animal Behaviour ScienceA comparison of cell-mediated immune responses in rhesus macaques housed singly, in pairs, or in groups. Applied Animal Behaviour Science. 68:67-84.A comparison of cell-mediated immune responses in rhesus macaques housed singly, in pairs, or in groupsRetrovirologyInfectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaques. Retrovirology. 13.Infectious SIV resides in adipose tissue and induces metabolic defects in chronically infected rhesus macaquesViral ImmunologyErratum. Viral Immunology. 12:89.ErratumCanadian Journal of MicrobiologyDifferences in the regulation of exocellular proteinase synthesis during growth and sporogenesis of Bacillus megaterium. Canadian Journal of Microbiology. 28:1214-1218.Differences in the regulation of exocellular proteinase synthesis during growth and sporogenesis of Bacillus megaterium19333387Weaver EA, Nehete PN, Buchl SS, Senac JS, Palmer D, Ng P, Sastry KJ, Barry MAPloS oneComparison of replication-competent, first generation, and helper-dependent adenoviral vaccines. PLoS One. 2009; 4(3):e5059.PLoS One2009-03-31T00:00:002009Comparison of replication-competent, first generation, and helper-dependent adenoviral vaccines.20667573Lay MK, Atmar RL, Guix S, Bharadwaj U, He H, Neill FH, Sastry KJ, Yao Q, Estes MKVirologyNorwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans. Virology. 2010 Oct 10; 406(1):1-11.Virology2010-07-29T00:00:002010Norwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans.D008253Living Beings1957210.82424Macaca mulattaD015497Living Beings2136560.679739HIV-1D010446Chemicals & Drugs55312690.639635Peptide FragmentsD016915Chemicals & Drugs25780.934104AIDS VaccinesD016097Disorders291090.931219Simian Acquired Immunodeficiency SyndromeAuthorship 9248629Authorship 93428819Authorship 93521513Authorship 939160429916059Filgueira CS, Bruno G, Smith ZW, Chua CYX, Ballerini A, Folci M, Gilbert AL, Jain P, Sastry JK, Nehete PN, Shelton KA, Hill LR, Ali A, Youker KA, Grattoni ABiomedical microdevicesEfficacy of sustained delivery of GC-1 from a Nanofluidic system in a spontaneously obese non-human primate: a case study. Biomed Microdevices. 2018 06 18; 20(2):49.Biomed Microdevices2018-06-18T00:00:002018Efficacy of sustained delivery of GC-1 from a Nanofluidic system in a spontaneously obese non-human primate: a case study.29982595Anguiano-Zarate SS, Matchett WE, Nehete PN, Sastry JK, Marzi A, Barry MAThe Journal of infectious diseasesA Replicating Single-Cycle Adenovirus Vaccine Against Ebola Virus. J Infect Dis. 2018 11 05; 218(12):1883-1889.J Infect Dis2018-11-05T00:00:002018A Replicating Single-Cycle Adenovirus Vaccine Against Ebola Virus.30017792Dorta-Estremera S, Colbert LE, Nookala SS, Yanamandra AV, Yang G, Delgado A, Mikkelson M, Eifel P, Jhingran A, Lilie LL, Welsh J, Schmeler K, Sastry JK, Klopp AInternational journal of radiation oncology, biology, physicsKinetics of Intratumoral Immune Cell Activation During Chemoradiation for Cervical Cancer. Int J Radiat Oncol Biol Phys. 2018 11 01; 102(3):593-600.Int J Radiat Oncol Biol Phys2018-07-12T00:00:002018Kinetics of Intratumoral Immune Cell Activation During Chemoradiation for Cervical Cancer.30092254Chua CYX, Jain P, Ballerini A, Bruno G, Hood RL, Gupte M, Gao S, Di Trani N, Susnjar A, Shelton K, Bushman LR, Folci M, Filgueira CS, Marzinke MA, Anderson PL, Hu M, Nehete P, Arduino RC, Sastry JK, Grattoni AJournal of controlled release : official journal of the Controlled Release SocietyTranscutaneously refillable nanofluidic implant achieves sustained level of tenofovir diphosphate for HIV pre-exposure prophylaxis. J Control Release. 2018 09 28; 286:315-325.J Control Release2018-08-06T00:00:002018Transcutaneously refillable nanofluidic implant achieves sustained level of tenofovir diphosphate for HIV pre-exposure prophylaxis.ImmunologyDepartment of PediatricsDepartment of Molecular Virology & MicrobiologyDepartment of RadiologyDepartment of UrologyRadiologyUrologyMolecular Virology & MicrobiologyPediatrics-Hem/Onc Cell & Gene TheBaylor College of MedicineJAMESCROWEJAMES CROWE0.000000000000000.000000000000001560CROWE, JAMESAssociate ProfessorDAVIDHODAVID HO29.71079220000000-95.40005120000000411HO, DAVIDClinical Assistant ProfessorCLIONAROONEYCLIONA ROONEY0.000000000000000.000000000000003578ROONEY, CLIONAProfessorANDREWRICEANDREW RICE0.000000000000000.000000000000003326RICE, ANDREWProfessor23844034Weaver EA, Nehete PN, Nehete BP, Yang G, Buchl SJ, Hanley PW, Palmer D, Montefiori DC, Ferrari G, Ng P, Sastry KJ, Barry MAPloS oneComparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV. PLoS One. 2013; 8(7):e67574.PLoS One2013-07-03T00:00:002013Comparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV.true1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate ProfessorAuthorship 10000891032975128Yang P, Rhea PR, Conway T, Nookala S, Hegde V, Gagea M, Ajami NJ, Harribance SL, Ochoa J, Sastry JK, Cohen LIntegrative cancer therapiesHuman Biofield Therapy Modulates Tumor Microenvironment and Cancer Stemness in Mouse Lung Carcinoma. Integr Cancer Ther. 2020 Jan-Dec; 19:1534735420940398.Integr Cancer Ther2020-01-01T00:00:002020Human Biofield Therapy Modulates Tumor Microenvironment and Cancer Stemness in Mouse Lung Carcinoma.33178829Qin H, Nehete PN, He H, Nehete B, Buchl S, Cha SC, Sastry JK, Kwak LWBioMed research internationalCorrigendum to "Prime-Boost Vaccination Using Chemokine-Fused gp120 DNA and HIV Envelope Peptides Activates Both Immediate and Long-Term Memory Cellular Responses in Rhesus Macaques". Biomed Res Int. 2020; 2020:5471638.Biomed Res Int2020-10-29T00:00:002020Corrigendum to "Prime-Boost Vaccination Using Chemokine-Fused gp120 DNA and HIV Envelope Peptides Activates Both Immediate and Long-Term Memory Cellular Responses in Rhesus Macaques".Authorship 10484407true1Assistant ProfessorAssistant ProfessorPediatricts-Oncology AICTAuthorship 1057660635914613Singh VK, Chau E, Mishra A, DeAnda A, Hegde VL, Sastry JK, Haviland D, Jagannath C, Godin B, Khan AJournal of controlled release : official journal of the Controlled Release SocietyCD44 receptor targeted nanoparticles augment immunity against tuberculosis in mice. J Control Release. 2022 09; 349:796-811.J Control Release2022-08-03T00:00:002022CD44 receptor targeted nanoparticles augment immunity against tuberculosis in mice.Authorship 10659889Authorship 1066156212590791Bhore AV, Sastry J, Patke D, Gupte N, Bulakh PM, Lele S, Karmarkar A, Bharucha KE, Shrotri A, Pisal H, Suryawanshi N, Tripathy S, Risbud AR, Paranjape RS, Shankar AV, Kshirsagar A, Phadke MA, Joshi PL, Brookmeyer RS, Bollinger RCInternational journal of STD & AIDSSensitivity and specificity of rapid HIV testing of pregnant women in India. Int J STD AIDS. 2003 Jan; 14(1):37-41.Int J STD AIDS2003-01-01T00:00:002003Sensitivity and specificity of rapid HIV testing of pregnant women in India.36935860Gjyshi O, Grippin A, Andring L, Jhingran A, Lin LL, Bronk J, Eifel PJ, Joyner MM, Sastry JK, Yoshida-Court K, Solley TN, Napravnik TC, O'Hara MP, Hegde VL, Colbert LE, Klopp AHClinical and translational radiation oncologyCirculating neutrophils and tumor-associated myeloid cells function as a powerful biomarker for response to chemoradiation in locally advanced cervical cancer. Clin Transl Radiat Oncol. 2023 Mar; 39:100578.Clin Transl Radiat Oncol2023-01-11T00:00:002023Circulating neutrophils and tumor-associated myeloid cells function as a powerful biomarker for response to chemoradiation in locally advanced cervical cancer.true1Clinical Assistant ProfessorClinical Assistant Professortrue1Associate ProfessorAssociate Professortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate Professortrue1Associate ProfessorAssociate ProfessorAMYCOURTNEYAMY COURTNEY8141COURTNEY, AMYAssistant Professor