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GILBERT COTE

TitleProfessor
InstitutionMD Anderson
DepartmentEndocrine Neoplasia & HD
Address1400 Pressler St
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wang JR, Montierth M, Xu L, Goswami M, Zhao X, Cote G, Wang W, Iyer P, Dadu R, Busaidy NL, Lai SY, Gross ND, Ferrarotto R, Lu C, Gunn GB, Williams MD, Routbort M, Zafereo ME, Cabanillas ME. Impact of Somatic Mutations on Survival Outcomes in Patients With Anaplastic Thyroid Carcinoma. JCO Precis Oncol. 2022 08; 6:e2100504. PMID: 35977347; PMCID: PMC10530586.
      Citations:    
    2. Adashek JJ, Desai AP, Andreev-Drakhlin AY, Roszik J, Cote GJ, Subbiah V. Hallmarks of RET and Co-occuring Genomic Alterations in RET-aberrant Cancers. Mol Cancer Ther. 2021 10; 20(10):1769-1776. PMID: 34493590; PMCID: PMC8492504.
      Citations: 1     Fields:    Translation:HumansAnimals
    3. Qin Y, Wang JR, Wang Y, Iyer P, Cote GJ, Busaidy NL, Dadu R, Zafereo M, Williams MD, Ferrarotto R, Gunn GB, Wei P, Patel K, Hofmann MC, Cabanillas ME. Clinical Utility of Circulating Cell-Free DNA Mutations in Anaplastic Thyroid Carcinoma. Thyroid. 2021 08; 31(8):1235-1243. PMID: 33599171; PMCID: PMC8420950.
      Citations: 6     Fields:    Translation:Humans
    4. Maniakas A, Dadu R, Busaidy NL, Wang JR, Ferrarotto R, Lu C, Williams MD, Gunn GB, Hofmann MC, Cote G, Sperling J, Gross ND, Sturgis EM, Goepfert RP, Lai SY, Cabanillas ME, Zafereo M. Evaluation of Overall Survival in Patients With Anaplastic Thyroid Carcinoma, 2000-2019. JAMA Oncol. 2020 09 01; 6(9):1397-1404. PMID: 32761153; PMCID: PMC7411939.
      Citations: 35     Fields:    Translation:Humans
    5. Grubbs EG, Lechan RM, Edeiken-Monroe B, Cote GJ, Trotter C, Tischler AS, Gagel RF. HEREDITARY ENDOCRINE TUMOURS: CURRENT STATE-OF-THE-ART AND RESEARCH OPPORTUNITIES: Early thyroidectomy in multiple endocrine neoplasia: a four decade experience. Endocr Relat Cancer. 2020 08; 27(8):T1-T8. PMID: 32464600.
      Citations:    Fields:    Translation:Humans
    6. Dadu R, Bagheri-Yarmand R, Ringel MD, Grubbs EG, Zafereo M, Cote G, Gagel RF, Robinson BG, Shaw KR, Hu MI. HEREDITARY ENDOCRINE TUMOURS: CURRENT STATE-OF-THE-ART AND RESEARCH OPPORTUNITIES: The state of science in medullary thyroid carcinoma: current challenges and unmet needs. Endocr Relat Cancer. 2020 08; 27(8):T27-T39. PMID: 32580150.
      Citations: 2     Fields:    Translation:Humans
    7. Subbiah V, Cote GJ. Advances in Targeting RET-Dependent Cancers. Cancer Discov. 2020 04; 10(4):498-505. PMID: 32094155; PMCID: PMC7125013.
      Citations: 25     Fields:    Translation:HumansCells
    8. Maxwell JE, Gule-Monroe MK, Subbiah V, Hu M, Perrier ND, Cabanillas ME, Lee JE, Graham PH, Cote GJ, Busaidy NL, Grubbs EG. Novel use of a Clinical Laboratory Improvements Amendments (CLIA)-certified Cyclin-Dependent Kinase N2C (CDKN2C) loss assay in?sporadic medullary thyroid carcinoma. Surgery. 2020 01; 167(1):80-86. PMID: 31648931.
      Citations: 4     Fields:    Translation:Humans
    9. Hurst Z, Liyanarachchi S, He H, Brock P, Sipos J, Nabhan F, Kebebew E, Green P, Cote GJ, Sherman S, Walker CJ, Chang YS, Xue S, Hollingsworth B, Li W, Genutis L, Menq E, de la Chapelle A, Jhiang SM. Risk Haplotypes Uniquely Associated with Radioiodine-Refractory Thyroid Cancer Patients of High African Ancestry. Thyroid. 2019 04; 29(4):530-539. PMID: 30654714; PMCID: PMC6457887.
      Citations: 3     Fields:    Translation:Humans
    10. Iyer PC, Cote GJ, Hai T, Gule-Monroe M, Bui-Griffith J, Williams MD, Hess K, Hofmann MC, Dadu R, Zafereo M, Busaidy NL, Ferrarotto R, Subbiah V, Gross N, Gunn BG, Skinner HD, Garden AS, Cabanillas ME, Iyer PC, Cote GJ, Hai T, Gule-Monroe M, Bui-Griffith J, Williams MD, Hess K, Hofmann MC, Dadu R, Zafereo M, Busaidy NL, Ferrarotto R, Subbiah V, Gross N, Gunn BG, Skinner HD, Garden AS, Cabanillas ME. Circulating BRAF V600E Cell-Free DNA as a Biomarker in the Management of Anaplastic Thyroid Carcinoma. JCO Precis Oncol. 2018 Dec; 2. PMID: 35135166; PMCID: PMC9797231.
      Citations: 1     Fields:    
    11. Bagheri-Yarmand R, Sinha KM, Li L, Lu Y, Cote GJ, Sherman SI, Gagel RF. Combinations of Tyrosine Kinase Inhibitor and ERAD Inhibitor Promote Oxidative Stress-Induced Apoptosis through ATF4 and KLF9 in Medullary Thyroid Cancer. Mol Cancer Res. 2019 03; 17(3):751-760. PMID: 30552230; PMCID: PMC6902859.
      Citations: 7     Fields:    Translation:HumansCells
    12. Fisher SB, Cote GJ, Bui-Griffith JH, Lu W, Tang X, Hai T, Fisher KE, Williams MD, Wistuba II, Waguespack SG, Dorman CM, Ludwig MS, Graham PH, Perrier ND, Lee JE, Grubbs EG. Genetic characterization of medullary thyroid cancer in childhood survivors of the Chernobyl accident. Surgery. 2019 01; 165(1):58-63. PMID: 30392857.
      Citations:    Fields:    Translation:HumansPHPublic Health
    13. Puli OR, Danysh BP, McBeath E, Sinha DK, Hoang NM, Powell RT, Danysh HE, Cabanillas ME, Cote GJ, Hofmann MC. The Transcription Factor ETV5 Mediates BRAFV600E-Induced Proliferation and TWIST1 Expression in Papillary Thyroid Cancer Cells. Neoplasia. 2018 11; 20(11):1121-1134. PMID: 30265861; PMCID: PMC6161370.
      Citations: 12     Fields:    Translation:HumansCells
    14. Valenciaga A, Saji M, Yu L, Zhang X, Bumrah C, Yilmaz AS, Knippler CM, Miles W, Giordano TJ, Cote GJ, Ringel MD. Transcriptional targeting of oncogene addiction in medullary thyroid cancer. JCI Insight. 2018 08 23; 3(16). PMID: 30135308; PMCID: PMC6141185.
      Citations: 7     Fields:    Translation:HumansCells
    15. Jaber T, Hyde SM, Cote GJ, Grubbs EG, Giles WH, Stevens CA, Dadu R. A Homozygous RET K666N Genotype With an MEN2A Phenotype. J Clin Endocrinol Metab. 2018 04 01; 103(4):1269-1272. PMID: 29408964.
      Citations:    Fields:    Translation:Humans
    16. Romero Arenas MA, Rich TA, Hyde SM, Busaidy NL, Cote GJ, Hu MI, Gagel RF, Gidley PW, Jimenez C, Kupferman ME, Peterson SK, Sherman SI, Ying A, Bassett RL, Waguespack SG, Perrier ND, Grubbs EG. Recontacting Patients with Updated Genetic Testing Recommendations for Medullary Thyroid Carcinoma and Pheochromocytoma or Paraganglioma. Ann Surg Oncol. 2018 May; 25(5):1395-1402. PMID: 29427212; PMCID: PMC10013431.
      Citations: 6     Fields:    Translation:Humans
    17. Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z. EGFR-Induced and PKCe Monoubiquitylation-Dependent NF-?B Activation Upregulates PKM2 Expression and Promotes Tumorigenesis. Mol Cell. 2018 01 18; 69(2):347. PMID: 29351852; PMCID: PMC5794337.
      Citations: 4     Fields:    
    18. Cabanillas ME, Zafereo M, Williams MD, Ferrarotto R, Dadu R, Gross N, Gunn GB, Skinner H, Cote G, Grosu HB, Iyer P, Busaidy NL. Recent advances and emerging therapies in anaplastic thyroid carcinoma. F1000Res. 2018; 7. PMID: 31583077; PMCID: PMC6753603.
      Citations: 13     Fields:    
    19. Valenciaga A, Grubbs EG, Porter K, Wakely PE, Williams MD, Cote GJ, Vasko VV, Saji M, Ringel MD. Reduced Retinoblastoma Protein Expression Is Associated with Decreased Patient Survival in Medullary Thyroid Cancer. Thyroid. 2017 12; 27(12):1523-1533. PMID: 29105562; PMCID: PMC5734142.
      Citations: 5     Fields:    Translation:Humans
    20. Christakis I, Qiu W, Hyde SM, Cote GJ, Grubbs EG, Perrier ND, Lee JE. Genotype-phenotype pancreatic neuroendocrine tumor relationship in multiple endocrine neoplasia type 1 patients: A 23-year experience at a single institution. Surgery. 2018 01; 163(1):212-217. PMID: 29122330.
      Citations: 7     Fields:    Translation:Humans
    21. Cote GJ, Evers C, Hu MI, Grubbs EG, Williams MD, Hai T, Duose DY, Houston MR, Bui JH, Mehrotra M, Waguespack SG, Busaidy NL, Cabanillas ME, Habra MA, Luthra R, Sherman SI. Prognostic Significance of Circulating RET M918T Mutated Tumor DNA in Patients With Advanced Medullary Thyroid Carcinoma. J Clin Endocrinol Metab. 2017 09 01; 102(9):3591-3599. PMID: 28911154; PMCID: PMC5587058.
      Citations: 22     Fields:    Translation:Humans
    22. El Naofal M, Kim A, Yon HY, Baity M, Ming Z, Bui-Griffith J, Tang Z, Robinson M, Grubbs EG, Cote GJ, Hu P. Role of CDKN2C Fluorescence In Situ Hybridization in the Management of Medullary Thyroid Carcinoma. Ann Clin Lab Sci. 2017 Sep; 47(5):523-528. PMID: 29066476; PMCID: PMC7057027.
      Citations: 2     Fields:    Translation:HumansCells
    23. Voss RK, Feng L, Lee JE, Perrier ND, Graham PH, Hyde SM, Nieves-Munoz F, Cabanillas ME, Waguespack SG, Cote GJ, Gagel RF, Grubbs EG. Medullary Thyroid Carcinoma in MEN2A: ATA Moderate- or High-Risk RET Mutations Do Not Predict Disease Aggressiveness. J Clin Endocrinol Metab. 2017 08 01; 102(8):2807-2813. PMID: 28609830; PMCID: PMC5546858.
      Citations: 16     Fields:    Translation:Humans
    24. Long KL, Etzel C, Rich T, Hyde S, Perrier ND, Graham PH, Lee JE, Hu MI, Cote GJ, Gagel R, Grubbs EG. All in the family? Analyzing the impact of family history in addition to genotype on medullary thyroid carcinoma aggressiveness in MEN2A patients. Fam Cancer. 2017 04; 16(2):283-289. PMID: 27864651.
      Citations: 4     Fields:    Translation:Humans
    25. Hyde SM, Cote GJ, Grubbs EG. Genetics of Multiple Endocrine Neoplasia Type 1/Multiple Endocrine Neoplasia Type 2 Syndromes. Endocrinol Metab Clin North Am. 2017 06; 46(2):491-502. PMID: 28476233.
      Citations:    Fields:    Translation:Humans
    26. Rao SN, Zafereo M, Dadu R, Busaidy NL, Hess K, Cote GJ, Williams MD, William WN, Sandulache V, Gross N, Gunn GB, Lu C, Ferrarotto R, Lai SY, Cabanillas ME. Patterns of Treatment Failure in Anaplastic Thyroid Carcinoma. Thyroid. 2017 05; 27(5):672-681. PMID: 28068873; PMCID: PMC5802249.
      Citations: 44     Fields:    Translation:Humans
    27. Sandulache VC, Williams MD, Lai SY, Lu C, William WN, Busaidy NL, Cote GJ, Singh RR, Luthra R, Cabanillas ME. Real-Time Genomic Characterization Utilizing Circulating Cell-Free DNA in Patients with Anaplastic Thyroid Carcinoma. Thyroid. 2017 01; 27(1):81-87. PMID: 27785980; PMCID: PMC5704769.
      Citations: 28     Fields:    Translation:Humans
    28. Grubbs EG, Williams MD, Scheet P, Vattathil S, Perrier ND, Lee JE, Gagel RF, Hai T, Feng L, Cabanillas ME, Cote GJ. Role of CDKN2C Copy Number in Sporadic Medullary Thyroid Carcinoma. Thyroid. 2016 11; 26(11):1553-1562. PMID: 27610696; PMCID: PMC6453497.
      Citations: 12     Fields:    Translation:Humans
    29. Xu JY, Grubbs EG, Waguespack SG, Jimenez C, Gagel RF, Sosa JA, Sellin RV, Dadu R, Hu MI, Trotter CS, Jackson M, Rich TA, Hyde SM, Sherman SI, Cote GJ. Medullary Thyroid Carcinoma Associated with Germline RETK666N Mutation. Thyroid. 2016 12; 26(12):1744-1751. PMID: 27673361; PMCID: PMC5175438.
      Citations:    Fields:    Translation:Humans
    30. Xu JY, Handy B, Michaelis CL, Waguespack SG, Hu MI, Busaidy N, Jimenez C, Cabanillas ME, Fritsche HA, Cote GJ, Sherman SI. Detection and Prognostic Significance of Circulating Tumor Cells in Patients With Metastatic Thyroid Cancer. J Clin Endocrinol Metab. 2016 11; 101(11):4461-4467. PMID: 27575943; PMCID: PMC5095245.
      Citations: 11     Fields:    Translation:HumansCells
    31. Georgescu MM, Gagea M, Cote G. NHERF1/EBP50 Suppresses Wnt-?-Catenin Pathway-Driven Intestinal Neoplasia. Neoplasia. 2016 08; 18(8):512-23. PMID: 27566107; PMCID: PMC5018097.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    32. Christakis I, Qiu W, Silva Figueroa AM, Hyde S, Cote GJ, Busaidy NL, Williams M, Grubbs E, Lee JE, Perrier ND. Clinical Features, Treatments, and Outcomes of Patients with Thymic Carcinoids and Multiple Endocrine Neoplasia Type 1 Syndrome at MD Anderson Cancer Center. Horm Cancer. 2016 08; 7(4):279-87. PMID: 27311764; PMCID: PMC10355947.
      Citations: 13     Fields:    Translation:Humans
    33. Li X, Qian X, Peng LX, Jiang Y, Hawke DH, Zheng Y, Xia Y, Lee JH, Cote G, Wang H, Wang L, Qian CN, Lu Z. Corrigendum: A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation. Nat Cell Biol. 2016 05 27; 18(6):709. PMID: 27230532.
      Citations: 1     Fields:    
    34. Danysh BP, Rieger EY, Sinha DK, Evers CV, Cote GJ, Cabanillas ME, Hofmann MC. Long-term vemurafenib treatment drives inhibitor resistance through a spontaneous KRAS G12D mutation in a BRAF V600E papillary thyroid carcinoma model. Oncotarget. 2016 May 24; 7(21):30907-23. PMID: 27127178; PMCID: PMC5058727.
      Citations: 30     Fields:    Translation:HumansCells
    35. Christakis I, Busaidy NL, Cote GJ, Williams MD, Hyde SM, Silva Figueroa AM, Kwatampora LJ, Clarke CN, Qiu W, Lee JE, Perrier ND. Parathyroid carcinoma and atypical parathyroid neoplasms in MEN1 patients; A clinico-pathologic challenge. The MD Anderson case series and review of the literature. Int J Surg. 2016 Jul; 31:10-6. PMID: 27212590.
      Citations: 14     Fields:    Translation:Humans
    36. Li X, Qian X, Peng LX, Jiang Y, Hawke DH, Zheng Y, Xia Y, Lee JH, Cote G, Wang H, Wang L, Qian CN, Lu Z. A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma?formation. Nat Cell Biol. 2016 05; 18(5):561-71. PMID: 27088854; PMCID: PMC4888794.
      Citations: 68     Fields:    Translation:HumansCells
    37. Bible KC, Cote GJ, Demeure MJ, Elisei R, Jhiang S, Ringel MD, International Thyroid Oncology Group Correlative Science Committee. Correlative Studies in Clinical Trials: A Position Statement From the International Thyroid Oncology Group. J Clin Endocrinol Metab. 2015 Dec; 100(12):4387-95. PMID: 26418285; PMCID: PMC5399506.
      Citations: 4     Fields:    Translation:Humans
    38. Phan LM, Fuentes-Mattei E, Wu W, Velazquez-Torres G, Sircar K, Wood CG, Hai T, Jimenez C, Cote GJ, Ozsari L, Hofmann MC, Zheng S, Verhaak R, Pagliaro L, Cortez MA, Lee MH, Yeung SC, Habra MA. Hepatocyte Growth Factor/cMET Pathway Activation Enhances Cancer Hallmarks in Adrenocortical Carcinoma. Cancer Res. 2015 Oct 01; 75(19):4131-42. PMID: 26282167; PMCID: PMC4592476.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    39. Rich T, Jackson M, Shah K, Cote GJ, Jimenez C, Roman-Gonzalez A. Metastatic sympathetic paraganglioma in a patient with loss of the SDHC gene. Fam Cancer. 2015 Dec; 14(4):615-9. PMID: 26162468.
      Citations: 5     Fields:    Translation:Humans
    40. Cote G, Baghdadi S, Bouvier-Capely C, Ritt A, Peroux A, Fevrier L, Rebiere F, Agarande M. Impact of the uranium (VI) speciation in mineralised urines on its extraction by?calix[6]arene bearing hydroxamic groups used in chromatography columns. Talanta. 2015 Nov 01; 144:875-82. PMID: 26452903.
      Citations: 3     Fields:    Translation:Cells
    41. Pozo K, Hillmann A, Augustyn A, Plattner F, Hai T, Singh T, Ramezani S, Sun X, Pfragner R, Minna JD, Cote GJ, Chen H, Bibb JA, Nwariaku FE. Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis. Oncotarget. 2015 May 20; 6(14):12080-93. PMID: 25900242; PMCID: PMC4494924.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    42. Bagheri-Yarmand R, Sinha KM, Gururaj AE, Ahmed Z, Rizvi YQ, Huang SC, Ladbury JE, Bogler O, Williams MD, Cote GJ, Gagel RF. A novel dual kinase function of the RET proto-oncogene negatively regulates activating transcription factor 4-mediated apoptosis. J Biol Chem. 2015 May 01; 290(18):11749-61. PMID: 25795775; PMCID: PMC4416875.
      Citations: 20     Fields:    Translation:HumansCells
    43. Cote GJ, Grubbs EG, Hofmann MC. Thyroid C-Cell Biology and Oncogenic Transformation. Recent Results Cancer Res. 2015; 204:1-39. PMID: 26494382; PMCID: PMC5640981.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    44. Grubbs EG, Ng PK, Bui J, Busaidy NL, Chen K, Lee JE, Lu X, Lu H, Meric-Bernstam F, Mills GB, Palmer G, Perrier ND, Scott KL, Shaw KR, Waguespack SG, Williams MD, Yelensky R, Cote GJ. RET fusion as a novel driver of medullary thyroid carcinoma. J Clin Endocrinol Metab. 2015 Mar; 100(3):788-93. PMID: 25546157; PMCID: PMC4333032.
      Citations: 34     Fields:    Translation:Humans
    45. Rich TA, Feng L, Busaidy N, Cote GJ, Gagel RF, Hu M, Jimenez C, Lee JE, Perrier N, Sherman SI, Waguespack SG, Ying A, Grubbs E. Prevalence by age and predictors of medullary thyroid cancer in patients with lower risk germline RET proto-oncogene mutations. Thyroid. 2014 Jul; 24(7):1096-106. PMID: 24617864; PMCID: PMC4080849.
      Citations: 13     Fields:    Translation:Humans
    46. Baudin E, Habra MA, Deschamps F, Cote G, Dumont F, Cabanillas M, Arfi-Roufe J, Berdelou A, Moon B, Al Ghuzlan A, Patel S, Leboulleux S, Jimenez C. Therapy of endocrine disease: treatment of malignant pheochromocytoma and paraganglioma. Eur J Endocrinol. 2014 Sep; 171(3):R111-22. PMID: 24891137.
      Citations: 42     Fields:    Translation:HumansAnimals
    47. Georgescu MM, Cote G, Agarwal NK, White CL. NHERF1/EBP50 controls morphogenesis of 3D colonic glands by stabilizing PTEN and ezrin-radixin-moesin proteins at the apical membrane. Neoplasia. 2014 Apr; 16(4):365-74.e1-2. PMID: 24862762; PMCID: PMC4094837.
      Citations: 22     Fields:    Translation:HumansCells
    48. Dadu R, Devine C, Hernandez M, Waguespack SG, Busaidy NL, Hu MI, Jimenez C, Habra MA, Sellin RV, Ying AK, Cote GJ, Sherman SI, Cabanillas ME. Role of salvage targeted therapy in differentiated thyroid cancer patients who failed first-line sorafenib. J Clin Endocrinol Metab. 2014 Jun; 99(6):2086-94. PMID: 24628550; PMCID: PMC4037722.
      Citations: 35     Fields:    Translation:Humans
    49. Agarwal NK, Zhu X, Gagea M, White CL, Cote G, Georgescu MM. PHLPP2 suppresses the NF-?B pathway by inactivating IKK? kinase. Oncotarget. 2014 Feb 15; 5(3):815-23. PMID: 24553260; PMCID: PMC3996652.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    50. Cabanillas ME, Hu MI, Jimenez C, Grubbs EG, Cote GJ. Treating medullary thyroid cancer in the age of targeted therapy. Int J Endocr Oncol. 2014; 1(2):203-216. PMID: 25908961; PMCID: PMC4405124.
      Citations: 6     
    51. Romero Arenas MA, Morris LF, Rich TA, Cote GJ, Grubbs EG, Waguespack SG, Perrier ND. Preoperative multiple endocrine neoplasia type 1 diagnosis improves the surgical outcomes of pediatric patients with primary hyperparathyroidism. J Pediatr Surg. 2014 Apr; 49(4):546-50. PMID: 24726110.
      Citations: 2     Fields:    Translation:Humans
    52. Thosani S, Ayala-Ramirez M, Palmer L, Hu MI, Rich T, Gagel RF, Cote G, Waguespack SG, Habra MA, Jimenez C. The characterization of pheochromocytoma and its impact on overall survival in multiple endocrine neoplasia type 2. J Clin Endocrinol Metab. 2013 Nov; 98(11):E1813-9. PMID: 24030942; PMCID: PMC5399523.
      Citations: 26     Fields:    Translation:Humans
    53. Tuvim MJ, Clement CG, Huang ES, Cote GJ, Evans SE, Lei X, Deftos LJ, Gagel RF, Dickey BF. Deletion of the gene encoding calcitonin and calcitonin gene-related peptide a does not affect the outcome of severe infection in mice. Am J Respir Cell Mol Biol. 2013 Jul; 49(1):151-5. PMID: 23526213; PMCID: PMC3727888.
      Citations: 2     Fields:    Translation:AnimalsCells
    54. Larsson CA, Cote G, Quint?s-Cardama A. The changing mutational landscape of acute myeloid leukemia and myelodysplastic syndrome. Mol Cancer Res. 2013 Aug; 11(8):815-27. PMID: 23645565; PMCID: PMC4123851.
      Citations: 32     Fields:    Translation:HumansCells
    55. Yang W, Xia Y, Cao Y, Zheng Y, Bu W, Zhang L, You MJ, Koh MY, Cote G, Aldape K, Li Y, Verma IM, Chiao PJ, Lu Z. EGFR-induced and PKCe monoubiquitylation-dependent NF-?B activation upregulates PKM2 expression and promotes tumorigenesis. Mol Cell. 2012 Dec 14; 48(5):771-84. PMID: 23123196; PMCID: PMC3526114.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    56. Cote GJ, Zhu W, Thomas A, Martin E, Murad F, Sharina IG. Hydrogen peroxide alters splicing of soluble guanylyl cyclase and selectively modulates expression of splicing regulators in human cancer cells. PLoS One. 2012; 7(7):e41099. PMID: 22911749; PMCID: PMC3401163.
      Citations: 10     Fields:    Translation:HumansCells
    57. Hu MI, Cote GJ. Medullary thyroid carcinoma: who's on first? Thyroid. 2012 May; 22(5):451-3. PMID: 22545752.
      Citations: 5     Fields:    Translation:Humans
    58. Dickson PV, Rich TA, Xing Y, Cote GJ, Wang H, Perrier ND, Evans DB, Lee JE, Grubbs EG. Achieving eugastrinemia in MEN1 patients: both duodenal inspection and formal lymph node dissection are important. Surgery. 2011 Dec; 150(6):1143-52. PMID: 22136834.
      Citations: 8     Fields:    Translation:Humans
    59. Izaguirre DI, Zhu W, Hai T, Cheung HC, Krahe R, Cote GJ. PTBP1-dependent regulation of USP5 alternative RNA splicing plays a role in glioblastoma tumorigenesis. Mol Carcinog. 2012 Nov; 51(11):895-906. PMID: 21976412; PMCID: PMC3319169.
      Citations: 38     Fields:    Translation:HumansCells
    60. Waguespack SG, Rich TA, Perrier ND, Jimenez C, Cote GJ. Management of medullary thyroid carcinoma and MEN2 syndromes in childhood. Nat Rev Endocrinol. 2011 Aug 23; 7(10):596-607. PMID: 21862994.
      Citations: 28     Fields:    Translation:Humans
    61. Sharina IG, Cote GJ, Martin E, Doursout MF, Murad F. RNA splicing in regulation of nitric oxide receptor soluble guanylyl cyclase. Nitric Oxide. 2011 Oct 30; 25(3):265-74. PMID: 21867767; PMCID: PMC3190046.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    62. Molina JR, Agarwal NK, Morales FC, Hayashi Y, Aldape KD, Cote G, Georgescu MM. PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma. Oncogene. 2012 Mar 08; 31(10):1264-74. PMID: 21804599; PMCID: PMC3208076.
      Citations: 86     Fields:    Translation:HumansCells
    63. Ayala-Ramirez M, Feng L, Johnson MM, Ejaz S, Habra MA, Rich T, Busaidy N, Cote GJ, Perrier N, Phan A, Patel S, Waguespack S, Jimenez C. Clinical risk factors for malignancy and overall survival in patients with pheochromocytomas and sympathetic paragangliomas: primary tumor size and primary tumor location as prognostic indicators. J Clin Endocrinol Metab. 2011 Mar; 96(3):717-25. PMID: 21190975.
      Citations: 138     Fields:    Translation:Humans
    64. Jasim S, Ying AK, Waguespack SG, Rich TA, Grubbs EG, Jimenez C, Hu MI, Cote G, Habra MA. Multiple endocrine neoplasia type 2B with a RET proto-oncogene A883F mutation displays a more indolent form of medullary thyroid carcinoma compared with a RET M918T mutation. Thyroid. 2011 Feb; 21(2):189-92. PMID: 21186952; PMCID: PMC3025175.
      Citations: 21     Fields:    Translation:Humans
    65. Gao Y, Fotovati A, Lee C, Wang M, Cote G, Guns E, Toyota B, Faury D, Jabado N, Dunn SE. Inhibition of Y-box binding protein-1 slows the growth of glioblastoma multiforme and sensitizes to temozolomide independent O6-methylguanine-DNA methyltransferase. Mol Cancer Ther. 2009 Dec; 8(12):3276-84. PMID: 19996271.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    66. Zhu W, Hai T, Ye L, Cote GJ. Medullary Thyroid Carcinoma Cell Lines Contain a Self-Renewing CD133+ Population that Is Dependent on RET Activity. Endocr Rev. 2009 Dec 01; 30(7):933. PMID: 28199507.
      Citations:    Fields:    
    67. Zhu W, Hai T, Ye L, Cote GJ. Medullary thyroid carcinoma cell lines contain a self-renewing CD133+ population that is dependent on ret proto-oncogene activity. J Clin Endocrinol Metab. 2010 Jan; 95(1):439-44. PMID: 19897677; PMCID: PMC2805480.
      Citations: 17     Fields:    Translation:HumansCells
    68. Hu J, He X, Cote GJ, Krahe R. Singular Value Decomposition-based Alternative Splicing Detection. J Am Stat Assoc. 2009 09 01; 104(487):944-953. PMID: 20305737; PMCID: PMC2841408.
      Citations: 3     
    69. Cheung HC, Hai T, Zhu W, Baggerly KA, Tsavachidis S, Krahe R, Cote GJ. Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines. Brain. 2009 Aug; 132(Pt 8):2277-88. PMID: 19506066; PMCID: PMC2724917.
      Citations: 76     Fields:    Translation:HumansCells
    70. Habra MA, Jimenez C, Huang SC, Cote GJ, Murphy WA, Gagel RF, Hoff AO. Expression analysis of fibroblast growth factor-23, matrix extracellular phosphoglycoprotein, secreted frizzled-related protein-4, and fibroblast growth factor-7: identification of fibroblast growth factor-23 and matrix extracellular phosphoglycoprotein as major factors involved in tumor-induced osteomalacia. Endocr Pract. 2008 Dec; 14(9):1108-14. PMID: 19158050.
      Citations: 10     Fields:    Translation:HumansCells
    71. Carrette F, Catalette H, Cote G, Barale M, Lef?vre G, F?doroff M. Effect of the adsorption of lithium and borate species on the zeta potential of particles of cobalt ferrite, nickel ferrite, and magnetite. J Colloid Interface Sci. 2008 Dec 01; 328(1):34-40. PMID: 18834597.
      Citations: 2     Fields:    
    72. Ye L, Santarpia L, Cote GJ, El-Naggar AK, Gagel RF. High resolution array-comparative genomic hybridization profiling reveals deoxyribonucleic acid copy number alterations associated with medullary thyroid carcinoma. J Clin Endocrinol Metab. 2008 Nov; 93(11):4367-72. PMID: 18765511; PMCID: PMC2729231.
      Citations: 17     Fields:    Translation:HumansCells
    73. Cheung HC, Baggerly KA, Tsavachidis S, Bachinski LL, Neubauer VL, Nixon TJ, Aldape KD, Cote GJ, Krahe R. Global analysis of aberrant pre-mRNA splicing in glioblastoma using exon expression arrays. BMC Genomics. 2008 May 12; 9:216. PMID: 18474104; PMCID: PMC2410136.
      Citations: 41     Fields:    Translation:HumansCells
    74. Grubbs EG, Rich TA, Li G, Sturgis EM, Younes MN, Myers JN, Edeiken-Monroe B, Fornage BD, Monroe DP, Staerkel GA, Williams MD, Waguespack SG, Hu MI, Cote G, Gagel RF, Cohen J, Weber RS, Anaya DA, Holsinger FC, Perrier ND, Clayman GL, Evans DB. Recent advances in thyroid cancer. In brief. Curr Probl Surg. 2008 Mar; 45(3):149-51. PMID: 18346476.
      Citations: 1     Fields:    Translation:Humans
    75. Grubbs EG, Rich TA, Li G, Sturgis EM, Younes MN, Myers JN, Edeiken-Monroe B, Fornage BD, Monroe DP, Staerkel GA, Williams MD, Waguespack SG, Hu MI, Cote G, Gagel RF, Cohen J, Weber RS, Anaya DA, Holsinger FC, Perrier ND, Clayman GL, Evans DB. Recent advances in thyroid cancer. Curr Probl Surg. 2008 Mar; 45(3):156-250. PMID: 18346477.
      Citations: 19     Fields:    Translation:Humans
    76. Santarpia L, El-Naggar AK, Cote GJ, Myers JN, Sherman SI. Phosphatidylinositol 3-kinase/akt and ras/raf-mitogen-activated protein kinase pathway mutations in anaplastic thyroid cancer. J Clin Endocrinol Metab. 2008 Jan; 93(1):278-84. PMID: 17989125.
      Citations: 78     Fields:    Translation:HumansCells
    77. Evans DB, Rich TA, Cote GJ. Surgical management of familial hyperparathyroidism. Ann Surg Oncol. 2007 May; 14(5):1525-7. PMID: 17285397.
      Citations: 2     Fields:    Translation:Humans
    78. Evans DB, Shapiro SE, Cote GJ. Invited commentary: medullary thyroid cancer: the importance of RET testing. Surgery. 2007 Jan; 141(1):96-9. PMID: 17188173.
      Citations: 2     Fields:    Translation:Humans
    79. Cote G, Arnold A, Gagel RF, Jim?nez C. Review: Should patients with apparently sporadic pheochromocytomas or paragangliomas be screened for hereditary syndromes? J Clin Endocrinol Metab. 2006 Aug; 91(8):2851-8. PMID: 16735498.
      Citations: 33     Fields:    Translation:Humans
    80. Cheung HC, Corley LJ, Fuller GN, McCutcheon IE, Cote GJ. Polypyrimidine tract binding protein and Notch1 are independently re-expressed in glioma. Mod Pathol. 2006 Aug; 19(8):1034-41. PMID: 16729017.
      Citations: 29     Fields:    Translation:Humans
    81. Kouvaraki MA, Shapiro SE, Cote GJ, Lee JE, Yao JC, Waguespack SG, Gagel RF, Evans DB, Perrier ND. Management of pancreatic endocrine tumors in multiple endocrine neoplasia type 1. World J Surg. 2006 May; 30(5):643-53. PMID: 16680581.
      Citations: 34     Fields:    Translation:Humans
    82. Kouvaraki MA, Shapiro SE, Perrier ND, Cote GJ, Gagel RF, Hoff AO, Sherman SI, Lee JE, Evans DB. RET proto-oncogene: a review and update of genotype-phenotype correlations in hereditary medullary thyroid cancer and associated endocrine tumors. Thyroid. 2005 Jun; 15(6):531-44. PMID: 16029119.
      Citations: 56     Fields:    Translation:Humans
    83. Jin W, Cote GJ. Enhancer-dependent splicing of FGFR1 alpha-exon is repressed by RNA interference-mediated down-regulation of SRp55. Cancer Res. 2004 Dec 15; 64(24):8901-5. PMID: 15604250.
      Citations: 11     Fields:    Translation:HumansCells
    84. Bruno IG, Jin W, Cote GJ. Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements. Hum Mol Genet. 2004 Oct 15; 13(20):2409-20. PMID: 15333583.
      Citations: 39     Fields:    Translation:HumansCells
    85. Jimenez C, Habra MA, Huang SC, El-Naggar A, Shapiro SE, Evans DB, Cote G, Gagel RF. Pheochromocytoma and medullary thyroid carcinoma: a new genotype-phenotype correlation of the RET protooncogene 891 germline mutation. J Clin Endocrinol Metab. 2004 Aug; 89(8):4142-5. PMID: 15292360.
      Citations: 4     Fields:    Translation:Humans
    86. Jimenez C, Dang GT, Schultz PN, El-Naggar A, Shapiro S, Barnes EA, Evans DB, Vassilopoulou-Sellin R, Gagel RF, Cote GJ, Hoff AO. A novel point mutation of the RET protooncogene involving the second intracellular tyrosine kinase domain in a family with medullary thyroid carcinoma. J Clin Endocrinol Metab. 2004 Jul; 89(7):3521-6. PMID: 15240641.
      Citations: 12     Fields:    Translation:HumansCells
    87. McCutcheon IE, Hentschel SJ, Fuller GN, Jin W, Cote GJ. Expression of the splicing regulator polypyrimidine tract-binding protein in normal and neoplastic brain. Neuro Oncol. 2004 Jan; 6(1):9-14. PMID: 14769134; PMCID: PMC1871971.
      Citations: 29     Fields:    Translation:HumansCells
    88. Shapiro SE, Cote GC, Lee JE, Gagel RF, Evans DB. The role of genetics in the surgical management of familial endocrinopathy syndromes. J Am Coll Surg. 2003 Nov; 197(5):818-31. PMID: 14585420.
      Citations: 4     Fields:    Translation:Humans
    89. Cote GJ, Gagel RF. Lessons learned from the management of a rare genetic cancer. N Engl J Med. 2003 Oct 16; 349(16):1566-8. PMID: 14561800.
      Citations: 5     Fields:    Translation:Humans
    90. Jin W, Bruno IG, Xie TX, Sanger LJ, Cote GJ. Polypyrimidine tract-binding protein down-regulates fibroblast growth factor receptor 1 alpha-exon inclusion. Cancer Res. 2003 Oct 01; 63(19):6154-7. PMID: 14559795.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    91. Yip L, Cote GJ, Shapiro SE, Ayers GD, Herzog CE, Sellin RV, Sherman SI, Gagel RF, Lee JE, Evans DB. Multiple endocrine neoplasia type 2: evaluation of the genotype-phenotype relationship. Arch Surg. 2003 Apr; 138(4):409-16; discussion 416. PMID: 12686527.
      Citations: 39     Fields:    Translation:Humans
    92. Frelon S, Cote G, Madic C, Paquet F. The contribution of chemical speciation to internal dosimetry. Radiat Prot Dosimetry. 2003; 105(1-4):179-84. PMID: 14535231.
      Citations: 5     Fields:    Translation:HumansAnimalsPHPublic Health
    93. Hoff AO, Catala-Lehnen P, Thomas PM, Priemel M, Rueger JM, Nasonkin I, Bradley A, Hughes MR, Ordonez N, Cote GJ, Amling M, Gagel RF. Increased bone mass is an unexpected phenotype associated with deletion of the calcitonin gene. J Clin Invest. 2002 Dec; 110(12):1849-57. PMID: 12488435; PMCID: PMC151647.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    94. Kikumori T, Cote GJ, Gagel RF. Naturally occurring heterologous trans-splicing of adenovirus RNA with host cellular transcripts during infection. FEBS Lett. 2002 Jul 03; 522(1-3):41-6. PMID: 12095616.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    95. Kouvaraki MA, Lee JE, Shapiro SE, Gagel RF, Sherman SI, Sellin RV, Cote GJ, Evans DB. Genotype-phenotype analysis in multiple endocrine neoplasia type 1. Arch Surg. 2002 Jun; 137(6):641-7. PMID: 12049533.
      Citations: 48     Fields:    Translation:Humans
    96. Kikumori T, Cote GJ, Gagel RF. Promiscuity of pre-mRNA spliceosome-mediated trans splicing: a problem for gene therapy? Hum Gene Ther. 2001 Jul 20; 12(11):1429-41. PMID: 11485634.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    97. Becker P, Youlton R, Cote GJ, Gagel RF, Wohllk N. [Germline mutations of the ret proto-oncogene in Chilean patients with hereditary and sporadic medullary thyroid carcinoma]. Rev Med Chil. 2001 Jul; 129(7):713-8. PMID: 11552438.
      Citations: 3     Fields:    Translation:HumansCells
    98. Thomas PM, Nasonkin I, Zhang H, Gagel RF, Cote GJ. Structure of the mouse calcitonin/calcitonin gene-related peptide alpha and beta genes. DNA Seq. 2001; 12(2):131-5. PMID: 11761712.
      Citations: 4     Fields:    Translation:AnimalsCells
    99. Zhang L, Hoff AO, Wimalawansa SJ, Cote GJ, Gagel RF, Westlund KN. Arthritic calcitonin/alpha calcitonin gene-related peptide knockout mice have reduced nociceptive hypersensitivity. Pain. 2001 Jan; 89(2-3):265-73. PMID: 11166483.
      Citations: 65     Fields:    Translation:AnimalsCells
    100. Jin W, McCutcheon IE, Fuller GN, Huang ES, Cote GJ. Fibroblast growth factor receptor-1 alpha-exon exclusion and polypyrimidine tract-binding protein in glioblastoma multiforme tumors. Cancer Res. 2000 Mar 01; 60(5):1221-4. PMID: 10728679.
      Citations: 43     Fields:    Translation:HumansCells
    101. Hoff AO, Cote GJ, Gagel RF. Multiple endocrine neoplasias. Annu Rev Physiol. 2000; 62:377-411. PMID: 10845096.
      Citations: 14     Fields:    Translation:HumansAnimals
    102. Hoff AO, Cote GJ, Fritsche HA, Qiu H, Schultz PN, Gagel RF. Calcium-induced activation of a mutant G-protein-coupled receptor causes in vitro transformation of NIH/3T3 cells. Neoplasia. 1999 Dec; 1(6):485-91. PMID: 10935495; PMCID: PMC1508117.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    103. Dackiw AP, Cote GJ, Fleming JB, Schultz PN, Stanford P, Vassilopoulou-Sellin R, Evans DB, Gagel RF, Lee JE. Screening for MEN1 mutations in patients with atypical endocrine neoplasia. Surgery. 1999 Dec; 126(6):1097-103; discussion 1103-4. PMID: 10598193.
      Citations: 14     Fields:    Translation:Humans
    104. Fleming JB, Lee JE, Bouvet M, Schultz PN, Sherman SI, Sellin RV, Friend KE, Burgess MA, Cote GJ, Gagel RF, Evans DB. Surgical strategy for the treatment of medullary thyroid carcinoma. Ann Surg. 1999 Nov; 230(5):697-707. PMID: 10561095; PMCID: PMC1420925.
      Citations: 20     Fields:    Translation:Humans
    105. Jin W, Huang ES, Bi W, Cote GJ. Redundant intronic repressors function to inhibit fibroblast growth factor receptor-1 alpha-exon recognition in glioblastoma cells. J Biol Chem. 1999 Sep 24; 274(39):28035-41. PMID: 10488155.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    106. Parthasarathy R, Cote GJ, Gagel RF. Hammerhead ribozyme-mediated inactivation of mutant RET in medullary thyroid carcinoma. Cancer Res. 1999 Aug 15; 59(16):3911-4. PMID: 10463581.
      Citations: 6     Fields:    Translation:AnimalsCells
    107. Dang GT, Cote GJ, Schultz PN, Khorana S, Decker RA, Gagel RF. A codon 891 exon 15 RET proto-oncogene mutation in familial medullary thyroid carcinoma: a detection strategy. Mol Cell Probes. 1999 Feb; 13(1):77-9. PMID: 10024437.
      Citations: 5     Fields:    Translation:Humans
    108. Otonkoski T, Huopio H, Cote GJ, Chapman J, Cosgrove K, Ashfield R, Huang E, Komulainen J, Ashcroft FM, Dunne MJ, Kere J, Thomas PM, Amm?l? C. A point mutation inactivating the sulfonylurea receptor causes the severe form of persistent hyperinsulinemic hypoglycemia of infancy in Finland. Diabetes. 1999 Feb; 48(2):408-15. PMID: 10334322.
      Citations: 39     Fields:    Translation:HumansAnimals
    109. Jin W, Bi W, Huang ES, Cote GJ. Glioblastoma cell-specific expression of fibroblast growth factor receptor-1beta requires an intronic repressor of RNA splicing. Cancer Res. 1999 Jan 15; 59(2):316-9. PMID: 9927039.
      Citations: 7     Fields:    Translation:HumansCells
    110. Evans DB, Fleming JB, Lee JE, Cote G, Gagel RF. The surgical treatment of medullary thyroid carcinoma. Semin Surg Oncol. 1999 Jan-Feb; 16(1):50-63. PMID: 9890740.
      Citations: 7     Fields:    Translation:Humans
    111. Wohllk N, Thomas PM, Huang E, Cote GJ. A human succinate-ubiquinone oxidoreductase CII-3 subunit gene ending in a polymorphic dinucleotide repeat is located within the sulfonylurea receptor (SUR) gene. Mol Genet Metab. 1998 Nov; 65(3):187-90. PMID: 9851882.
      Citations: 4     Fields:    Translation:HumansCells
    112. Jin W, Huang ES, Bi W, Cote GJ. Exon sequence is required for regulated RNA splicing of the human fibroblast growth factor receptor-1 alpha-exon. J Biol Chem. 1998 Jun 26; 273(26):16170-6. PMID: 9632672.
      Citations: 3     Fields:    Translation:HumansCells
    113. Shefelbine SE, Khorana S, Schultz PN, Huang E, Thobe N, Hu ZJ, Fox GM, Jing S, Cote GJ, Gagel RF. Mutational analysis of the GDNF/RET-GDNFR alpha signaling complex in a kindred with vesicoureteral reflux. Hum Genet. 1998 Apr; 102(4):474-8. PMID: 9600247.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    114. Cote GJ, Lee JE, Evans DB, Huang E, Schultz PN, Dang GT, Qiu H, Shetelbine S, Sellin RV, Gagel RF. Five novel mutations in the familial multiple endocrine neoplasia type 1 (MEN1) gene. Mutations in brief no. 188. Online. Hum Mutat. 1998; 12(3):219. PMID: 10660339.
      Citations: 1     Fields:    Translation:Humans
    115. Deftos LJ, Nolan JJ, Seely BL, Clopton PL, Cote GJ, Whitham CL, Florek LJ, Christensen TA, Hill MR. Intrapulmonary drug delivery of salmon calcitonin. Calcif Tissue Int. 1997 Oct; 61(4):345-7. PMID: 9312206.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    116. Khachatryan A, Guerder S, Palluault F, Cote G, Solimena M, Valentijn K, Millet I, Flavell RA, Vignery A. Targeted expression of the neuropeptide calcitonin gene-related peptide to beta cells prevents diabetes in NOD mice. J Immunol. 1997 Feb 01; 158(3):1409-16. PMID: 9013986.
      Citations: 7     Fields:    Translation:AnimalsCells
    117. Cote GJ, Huang ES, Jin W, Morrison RS. Sequence requirements for regulated RNA splicing of the human fibroblast growth factor receptor-1 alpha exon. J Biol Chem. 1997 Jan 10; 272(2):1054-60. PMID: 8995402.
      Citations: 2     Fields:    Translation:HumansCells
    118. Eng C, Clayton D, Schuffenecker I, Lenoir G, Cote G, Gagel RF, van Amstel HK, Lips CJ, Nishisho I, Takai SI, Marsh DJ, Robinson BG, Frank-Raue K, Raue F, Xue F, Noll WW, Romei C, Pacini F, Fink M, Niederle B, Zedenius J, Komminoth P, Hendy GN, Mulligan LM, Nordenskj?ld M, et al. The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2. International RET mutation consortium analysis. JAMA. 1996 Nov 20; 276(19):1575-9. PMID: 8918855.
      Citations: 262     Fields:    Translation:Humans
    119. Wohllk N, Cote GJ, Bugalho MM, Ordonez N, Evans DB, Goepfert H, Khorana S, Schultz P, Richards CS, Gagel RF. Relevance of RET proto-oncogene mutations in sporadic medullary thyroid carcinoma. J Clin Endocrinol Metab. 1996 Oct; 81(10):3740-5. PMID: 8855832.
      Citations: 29     Fields:    Translation:HumansCells
    120. Thomas PM, Wohllk N, Huang E, Kuhnle U, Rabl W, Gagel RF, Cote GJ. Inactivation of the first nucleotide-binding fold of the sulfonylurea receptor, and familial persistent hyperinsulinemic hypoglycemia of infancy. Am J Hum Genet. 1996 Sep; 59(3):510-8. PMID: 8751851; PMCID: PMC1914902.
      Citations: 12     Fields:    Translation:HumansCells
    121. Kahn MA, Cote GJ, Gagel RF. RET protooncogene mutational analysis in multiple endocrine neoplasia syndrome type 2B: case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996 Sep; 82(3):288-94. PMID: 8884827.
      Citations: 3     Fields:    Translation:HumansCells
    122. Wohllk N, Cote GJ, Evans DB, Goepfert H, Ordonez NG, Gagel RF. Application of genetic screening information to the management of medullary thyroid carcinoma and multiple endocrine neoplasia type 2. Endocrinol Metab Clin North Am. 1996 Mar; 25(1):1-25. PMID: 8907678.
      Citations: 5     Fields:    Translation:HumansCells
    123. Thomas PM, Cote GJ, Wohllk N, Mathew PM, Gagel RF. The molecular basis for familial persistent hyperinsulinemic hypoglycemia of infancy. Proc Assoc Am Physicians. 1996 Jan; 108(1):14-9. PMID: 8834059.
      Citations: 3     Fields:    Translation:Humans
    124. Lou H, Yang Y, Cote GJ, Berget SM, Gagel RF. An intron enhancer containing a 5' splice site sequence in the human calcitonin/calcitonin gene-related peptide gene. Mol Cell Biol. 1995 Dec; 15(12):7135-42. PMID: 8524281; PMCID: PMC230969.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    125. Gagel RF, Cote GJ, Martins Bugalho MJ, Boyd AE, Cummings T, Goepfert H, Evans DB, Cangir A, Khorana S, Schultz PN. Clinical use of molecular information in the management of multiple endocrine neoplasia type 2A. J Intern Med. 1995 Oct; 238(4):333-41. PMID: 7595169.
      Citations: 6     Fields:    Translation:HumansCells
    126. Cote GJ, Wohllk N, Evans D, Goepfert H, Gagel RF. RET proto-oncogene mutations in multiple endocrine neoplasia type 2 and medullary thyroid carcinoma. Baillieres Clin Endocrinol Metab. 1995 Jul; 9(3):609-30. PMID: 7575334.
      Citations: 3     Fields:    Translation:Humans
    127. Thomas PM, Cote GJ, Wohllk N, Haddad B, Mathew PM, Rabl W, Aguilar-Bryan L, Gagel RF, Bryan J. Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy. Science. 1995 Apr 21; 268(5209):426-9. PMID: 7716548.
      Citations: 189     Fields:    Translation:HumansCells
    128. Thomas PM, Cote GJ, Hallman DM, Mathew PM. Homozygosity mapping, to chromosome 11p, of the gene for familial persistent hyperinsulinemic hypoglycemia of infancy. Am J Hum Genet. 1995 Feb; 56(2):416-21. PMID: 7847376; PMCID: PMC1801118.
      Citations: 14     Fields:    Translation:HumansCells
    129. Lou H, Cote GJ, Gagel RF. The calcitonin exon and its flanking intronic sequences are sufficient for the regulation of human calcitonin/calcitonin gene-related peptide alternative RNA splicing. Mol Endocrinol. 1994 Dec; 8(12):1618-26. PMID: 7535892.
      Citations: 6     Fields:    Translation:HumansCells
    130. Bugalho MJ, Cote GJ, Khorana S, Schultz PN, Gagel RF. Identification of a polymorphism in exon 11 of the RET protooncogene. Hum Mol Genet. 1994 Dec; 3(12):2263. PMID: 7881435.
      Citations: 6     Fields:    Translation:HumansCells
    131. Leaf A, Jorgensen MB, Jacobs AK, Cote G, Schoenfeld DA, Scheer J, Weiner BH, Slack JD, Kellett MA, Raizner AE, et al. Do fish oils prevent restenosis after coronary angioplasty? Circulation. 1994 Nov; 90(5):2248-57. PMID: 7955181.
      Citations: 41     Fields:    Translation:HumansCTClinical Trials
    132. Khorana S, Gagel RF, Cote GJ. Direct sequencing of PCR products in agarose gel slices. Nucleic Acids Res. 1994 Aug 25; 22(16):3425-6. PMID: 7915835; PMCID: PMC523740.
      Citations: 13     Fields:    Translation:HumansCells
    133. Cote GJ. Alternative RNA splicing of calcitonin/calcitonin gene-related peptide minigene transcripts in a thyroid C-cell line. Biochem Biophys Res Commun. 1994 Apr 29; 200(2):993-8. PMID: 8179637.
      Citations:    Fields:    Translation:HumansCells
    134. Cote GJ, Stolow DT, Peleg S, Berget SM, Gagel RF. Identification of exon sequences and an exon binding protein involved in alternative RNA splicing of calcitonin/CGRP. Nucleic Acids Res. 1992 May 11; 20(9):2361-6. PMID: 1594453; PMCID: PMC312354.
      Citations: 19     Fields:    Translation:HumansCells
    135. Cote GJ, Nguyen IN, Lips CJ, Berget SM, Gagel RF. Validation of an in vitro RNA processing system for CT/CGRP precursor mRNA. Nucleic Acids Res. 1991 Jul 11; 19(13):3601-6. PMID: 1649451; PMCID: PMC328385.
      Citations: 8     Fields:    Translation:Cells
    136. Cote GJ, Nguyen IN, Berget SM, Gagel RF. Calcitonin exon sequences influence alternative RNA processing. Mol Endocrinol. 1990 Nov; 4(11):1744-9. PMID: 2280774.
      Citations: 8     Fields:    Translation:HumansCells
    137. Peleg S, Abruzzese RV, Cote GJ, Gagel RF. Transcription of the human calcitonin gene is mediated by a C cell-specific enhancer containing E-box-like elements. Mol Endocrinol. 1990 Nov; 4(11):1750-7. PMID: 2280775.
      Citations: 9     Fields:    Translation:AnimalsCells
    138. Cote GJ, Abruzzese RV, Lips CJ, Gagel RF. Transfection of calcitonin gene regulatory elements into a cell culture model of the C cell. J Bone Miner Res. 1990 Feb; 5(2):165-71. PMID: 2316404.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    139. Robberson BL, Cote GJ, Berget SM. Exon definition may facilitate splice site selection in RNAs with multiple exons. Mol Cell Biol. 1990 Jan; 10(1):84-94. PMID: 2136768; PMCID: PMC360715.
      Citations: 324     Fields:    Translation:AnimalsCells
    140. Rogers DG, Cote GJ, Huang ES, Gagel RF. 1,25-Dihydroxyvitamin D3 silences 3',5'-cyclic adenosine monophosphate enhancement of somatostatin gene transcription in human thyroid C cells. Mol Endocrinol. 1989 Mar; 3(3):547-51. PMID: 2568585.
      Citations: 1     Fields:    Translation:HumansCells
    141. Cote GJ, Huang ES, Gagel RF. Calcitonin production: an examination of the regulatory effects of extracellular calcium and 1,25-dihydroxyvitamin D3. Horm Metab Res Suppl. 1989; 21:15-8. PMID: 2807150.
      Citations: 1     Fields:    Translation:HumansCells
    142. Peleg S, Cote GJ, Abruzzese RV, Gagel RF. Transcriptional regulation of the human calcitonin gene: a progress report. Henry Ford Hosp Med J. 1989; 37(3-4):194-7. PMID: 2639134.
      Citations:    Fields:    Translation:HumansCells
    143. Cote G, Jequier S, Kaplan P. Increased renal medullary echogenicity in patients with Williams syndrome. Pediatr Radiol. 1989; 19(6-7):481-3. PMID: 2671904.
      Citations: 1     Fields:    Translation:Humans
    144. Cote G, Psilas K, Kitsos G. [An example of dominant heredity in the transmission of primary open-angle glaucoma in a northwestern region of Greece]. J Fr Ophtalmol. 1988; 11(12):859-64. PMID: 3253316.
      Citations: 3     Fields:    Translation:Humans
    145. Cote GJ, Rogers DG, Huang ES, Gagel RF. The effect of 1,25-dihydroxyvitamin D3 treatment on calcitonin and calcitonin gene-related peptide mRNA levels in cultured human thyroid C-cells. Biochem Biophys Res Commun. 1987 Nov 30; 149(1):239-43. PMID: 3500723.
      Citations: 11     Fields:    Translation:HumansCells
    146. Cote GJ, Gould JA, Huang SC, Gagel RF. Studies of short-term secretion of peptides produced by alternative RNA processing. Mol Cell Endocrinol. 1987 Oct; 53(3):211-9. PMID: 2822513.
      Citations:    Fields:    Translation:Cells
    147. Wen BG, Burkhard AL, Cote GJ, Huang DP, Chiu JF. Hepatoma-associated nonhistone chromosomal proteins are present in active chromatin. Mol Cell Biochem. 1987 Jul; 76(1):75-84. PMID: 2442595.
      Citations:    Fields:    Translation:AnimalsCells
    148. Cote GJ, Chiu JF. The expressions of oncogenes and liver-specific genes in Morris hepatomas. Biochem Biophys Res Commun. 1987 Mar 13; 143(2):624-9. PMID: 2436615.
      Citations: 1     Fields:    Translation:Animals
    149. Wang Z, Cote GJ, Chiu JF. A specific alpha-fetoprotein gene binding protein in alpha-fetoprotein producing rat hepatomas. Biochem Biophys Res Commun. 1987 Feb 27; 143(1):110-5. PMID: 2435286.
      Citations:    Fields:    Translation:AnimalsCells
    150. Cote GJ, Gagel RF. Different mechanisms of calcitonin, calcitonin gene-related peptide, and somatostatin regulation by glucocorticoids in a cell culture of human medullary thyroid carcinoma. Henry Ford Hosp Med J. 1987; 35(2-3):149-52. PMID: 2891648.
      Citations: 1     Fields:    Translation:HumansCells
    151. Cote GJ, Gagel RF. Dexamethasone differentially affects the levels of calcitonin and calcitonin gene-related peptide mRNAs expressed in a human medullary thyroid carcinoma cell line. J Biol Chem. 1986 Nov 25; 261(33):15524-8. PMID: 3491070.
      Citations: 10     Fields:    Translation:HumansCells
    152. Cote GJ, Palmer WN, Leonhart K, Leong SS, Gagel RF. The regulation of somatostatin production in human medullary thyroid carcinoma cells by dexamethasone. J Biol Chem. 1986 Oct 05; 261(28):12930-5. PMID: 2875992.
      Citations: 4     Fields:    Translation:HumansCells
    153. Cote GJ, Wang Z, Chiu JF. alpha-Fetoprotein gene DNA-binding proteins. Arch Biochem Biophys. 1985 Nov 15; 243(1):320-4. PMID: 2415063.
      Citations: 2     Fields:    Translation:Animals
    154. Huang DP, Cote GJ, Massari RJ, Chiu JF. Dexamethasone inhibits alpha-fetoprotein gene transcription in neonatal rat liver and isolated nuclei. Nucleic Acids Res. 1985 Jun 11; 13(11):3873-90. PMID: 2409527; PMCID: PMC341283.
      Citations: 4     Fields:    Translation:AnimalsCells
    155. Cote GJ, Lastra BA, Cook JR, Huang DP, Chiu JF. Oncogene expression in rat hepatomas and during hepatocarcinogenesis. Cancer Lett. 1985 Mar; 26(2):121-7. PMID: 3978602.
      Citations: 7     Fields:    Translation:Animals
    156. Cote GJ, Chiu JF. Tissue specific control of alpha-fetoprotein gene expression. Biochem Biophys Res Commun. 1984 Apr 30; 120(2):677-85. PMID: 6203525.
      Citations: 1     Fields:    Translation:AnimalsCells
    157. Huang DP, Cote GJ, Ho KL, Chiu JF. The enhancement of specific gene transcription in isolated nuclei by added HeLa whole cell extract. Int J Biochem. 1984; 16(9):963-9. PMID: 6207060.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    158. Chiu JF, Huang DP, Burkhardt AL, Cote G, Schwartz CE. The alteration of gene expression in rat liver during chemical carcinogenesis. Arch Biochem Biophys. 1983 Apr 01; 222(1):310-20. PMID: 6838226.
      Citations: 4     Fields:    Translation:AnimalsCells
    159. All in the family? Analyzing the impact of family history in addition to genotype on medullary thyroid carcinoma aggressiveness in MEN2A patients. Familial Cancer. 1-7.
    160. Hepatocyte Growth Factor/cMET Pathway Activation Enhances Cancer Hallmarks in Adrenocortical Carcinoma. Cancer Research. 75:4131-4142.
    161. Tissue specificity of alpha-fetoprotein gene binding proteins. Federation Proceedings. 44.
    162. Long-Term vemurafenib treatment drives inhibitor resistance through a spontaneous KRAS G12D mutation in a BRAF V600E papillary thyroid carcinoma model. Oncotarget. 7:30907-30923.
    163. Detection and prognostic significance of circulating tumor cells in patients with metastatic thyroid cancer. Journal of Clinical Endocrinology and Metabolism. 101:4461-4467.
    164. Alpha-fetoprotein gene binding proteins.
    165. Molecular Diagnosis of Bone and Mineral Disorders. 193-196.
    166. NHERF1/EBP50 Suppresses Wnt-β-Catenin Pathway-Driven Intestinal Neoplasia. Neoplasia (United States).
    167. Examination of the alternative pathways of calcitonin pre-mRNA maturation in an in vitro RNA processing system. 64-68.
    168. Clinical Features, Treatments, and Outcomes of Patients with Thymic Carcinoids and Multiple Endocrine Neoplasia Type 1 Syndrome at MD Anderson Cancer Center. Hormones and Cancer. 1-9.
    169. Erratum. Human Molecular Genetics. 13:2725.
    170. Parathyroid carcinoma and atypical parathyroid neoplasms in MEN1 patients; A clinico-pathologic challenge. The MD Anderson case series and review of the literature. International Journal of Surgery. 31:10-16.
    171. A splicing switch from ketohexokinase-C to ketohexokinase-A drives hepatocellular carcinoma formation. Nature Cell Biology. 18:561-571.
    172. Medullary Thyroid Carcinoma Associated with Germline RETK666N Mutation. Thyroid. 26:1744-1751.
    173. Singular value decomposition-based alternative splicing detection. Journal of the American Statistical Association. 104:944-953.
    174. Real-Time Genomic Characterization Utilizing Circulating Cell-Free DNA in Patients with Anaplastic Thyroid Carcinoma. Thyroid. 27:81-87.
    175. Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis. Oncotarget. 6:12080-12093.
    176. Multiple endocrine neoplasia type 2. 393-399.
    177. Erratum. Nature Cell Biology. 18:709.
    178. Correlative studies in clinical trials. Journal of Clinical Endocrinology and Metabolism. 100:4387-4395.
    179. Role of CDKN2C copy number in sporadic medullary thyroid carcinoma. Thyroid. 26:1553-1562.
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