DANIELCARSONDANIEL CARSON 8233CARSON, DANIELSchlumberger Chair of Advanced Studies & Research; Professor of Biochemistry & Cell Biologyprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipDepartmentDivisionvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson6100 Main StreetHouston77005TXBioSciences at RiceRice UniversityCINDYFARACH-CARSONCINDY FARACH-CARSON 8234FARACH-CARSON, CINDYR & D Looney Professor3.479820.00468279208research areas0.4806940.0272468coauthor of18.9093.6427460similar to1133selected publicationsAuthorship 1576776Authorship 1577163Authorship 1577564Authorship 1577588Authorship 1577683Authorship 1577724Authorship 1577734Authorship 1577843Authorship 1578027Authorship 1578042Authorship 1578113Authorship 1578164Authorship 1578207Authorship 1578255Authorship 1578287Authorship 1578584Authorship 1578756Authorship 1578934Authorship 1579035Authorship 1579163Authorship 1579716Authorship 1580065Authorship 1580184Authorship 1580493Authorship 158125425062510Silva AL, Fuhrich DG, Carson DD, Engel BJ, Savaris RFEuropean journal of obstetrics, gynecology, and reproductive biologyMUC1 expression in fallopian tubes of women with hydrosalpinx. Eur J Obstet Gynecol Reprod Biol. 2014 Sep; 180:106-10.Eur J Obstet Gynecol Reprod Biol2014-06-25T00:00:002014MUC1 expression in fallopian tubes of women with hydrosalpinx.22916077Danysh BP, Constantinou PE, Lukianova-Hleb EY, Lapotko DO, Carson DDTheranosticsThe MUC1 Ectodomain: A Novel and Efficient Target for Gold Nanoparticle Clustering and Vapor Nanobubble Generation. Theranostics. 2012; 2(8):777-87.Theranostics2012-08-09T00:00:002012The MUC1 Ectodomain: A Novel and Efficient Target for Gold Nanoparticle Clustering and Vapor Nanobubble Generation.Cancer BiologyCancer Systems ImagingGynecological Oncology & Reproductive MedicineTranslational Molecular PathologyMD AndersonAMY BHEIMBERGERAMY B HEIMBERGER9035HEIMBERGER, AMY BProfessorKRISHNA PBHATKRISHNA P BHAT8976BHAT, KRISHNA PAssistant ProfessorPRATIP KBHATTACHARYAPRATIP K BHATTACHARYA9816BHATTACHARYA, PRATIP KAssociate ProfessorRAGHUKALLURIRAGHU KALLURI9841KALLURI, RAGHUProfessorANIL KSOODANIL K SOOD9048SOOD, ANIL KProfessor83R & D Looney Professor86Schlumberger Chair of Advanced Studies & Research; Professor of Biochemistry & Cell Biology11771669French MM, Gomes RR, Timpl R, H??k M, Czymmek K, Farach-Carson MC, Carson DDJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchChondrogenic activity of the heparan sulfate proteoglycan perlecan maps to the N-terminal domain I. J Bone Miner Res. 2002 Jan; 17(1):48-55.J Bone Miner Res2002-01-01T00:00:002002Chondrogenic activity of the heparan sulfate proteoglycan perlecan maps to the N-terminal domain I.12238817Liu R, Rohe B, Carson DD, Farach-Carson MCAntisense & nucleic acid drug developmentA rapid and simple nonradioactive method for in vitro testing of ribozyme activity. Antisense Nucleic Acid Drug Dev. 2002 Aug; 12(4):283-8.Antisense Nucleic Acid Drug Dev2002-08-01T00:00:002002A rapid and simple nonradioactive method for in vitro testing of ribozyme activity.74Professor10Assistant Professor14Associate Professor6Adjunct Professor15831077Farach-Carson MC, Hecht JT, Carson DDCritical reviews in eukaryotic gene expressionHeparan sulfate proteoglycans: key players in cartilage biology. Crit Rev Eukaryot Gene Expr. 2005; 15(1):29-48.Crit Rev Eukaryot Gene Expr2005-01-01T00:00:002005Heparan sulfate proteoglycans: key players in cartilage biology.17507691D'Souza SS, Daikoku T, Farach-Carson MC, Carson DDBiology of reproductionHeparanase expression and function during early pregnancy in mice. Biol Reprod. 2007 Sep; 77(3):433-41.Biol Reprod2007-05-16T00:00:002007Heparanase expression and function during early pregnancy in mice.17997086Farach-Carson MC, Brown AJ, Lynam M, Safran JB, Carson DDMatrix biology : journal of the International Society for Matrix BiologyA novel peptide sequence in perlecan domain IV supports cell adhesion, spreading and FAK activation. Matrix Biol. 2008 Mar; 27(2):150-60.Matrix Biol2007-10-10T00:00:002007A novel peptide sequence in perlecan domain IV supports cell adhesion, spreading and FAK activation.15696579Al-Shami R, Sorensen ES, Ek-Rylander B, Andersson G, Carson DD, Farach-Carson MCJournal of cellular biochemistryPhosphorylated osteopontin promotes migration of human choriocarcinoma cells via a p70 S6 kinase-dependent pathway. J Cell Biochem. 2005 Apr 15; 94(6):1218-33.J Cell Biochem2005-04-15T00:00:002005Phosphorylated osteopontin promotes migration of human choriocarcinoma cells via a p70 S6 kinase-dependent pathway.16826426Muir C, Chung LW, Carson DD, Farach-Carson MCClinical & experimental metastasisHypoxia increases VEGF-A production by prostate cancer and bone marrow stromal cells and initiates paracrine activation of bone marrow endothelial cells. Clin Exp Metastasis. 2006; 23(1):75-86.Clin Exp Metastasis2006-07-07T00:00:002006Hypoxia increases VEGF-A production by prostate cancer and bone marrow stromal cells and initiates paracrine activation of bone marrow endothelial cells.16889529Yang W, Gomes RR, Brown AJ, Burdett AR, Alicknavitch M, Farach-Carson MC, Carson DDTissue engineeringChondrogenic differentiation on perlecan domain I, collagen II, and bone morphogenetic protein-2-based matrices. Tissue Eng. 2006 Jul; 12(7):2009-24.Tissue Eng2006-07-01T00:00:002006Chondrogenic differentiation on perlecan domain I, collagen II, and bone morphogenetic protein-2-based matrices.16026543Hecht JT, Hayes E, Haynes R, Cole WG, Long RJ, Farach-Carson MC, Carson DDDifferentiation; research in biological diversityDifferentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes. Differentiation. 2005 Jun; 73(5):212-21.Differentiation2005-06-01T00:00:002005Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes.17442708Farach-Carson MC, Carson DDGlycobiologyPerlecan--a multifunctional extracellular proteoglycan scaffold. Glycobiology. 2007 Sep; 17(9):897-905.Glycobiology2007-04-18T00:00:002007Perlecan--a multifunctional extracellular proteoglycan scaffold.17579118O'Connor JC, Farach-Carson MC, Schneider CJ, Carson DDMolecular cancer research : MCRCoculture with prostate cancer cells alters endoglin expression and attenuates transforming growth factor-beta signaling in reactive bone marrow stromal cells. Mol Cancer Res. 2007 Jun; 5(6):585-603.Mol Cancer Res2007-06-01T00:00:002007Coculture with prostate cancer cells alters endoglin expression and attenuates transforming growth factor-beta signaling in reactive bone marrow stromal cells.17989358D'Souza SS, Fazleabas AT, Banerjee P, Sherwin JR, Sharkey AM, Farach-Carson MC, Carson DDBiology of reproductionDecidual heparanase activity is increased during pregnancy in the baboon (Papio anubis) and in in vitro decidualization of human stromal cells. Biol Reprod. 2008 Feb; 78(2):316-23.Biol Reprod2007-11-07T00:00:002007Decidual heparanase activity is increased during pregnancy in the baboon (Papio anubis) and in in vitro decidualization of human stromal cells.18980226D'Souza S, Yang W, Marchetti D, Muir C, Farach-Carson MC, Carson DDJournal of cellular biochemistryHIP/RPL29 antagonizes VEGF and FGF2 stimulated angiogenesis by interfering with HS-dependent responses. J Cell Biochem. 2008 Dec 01; 105(5):1183-93.J Cell Biochem2008-12-01T00:00:002008HIP/RPL29 antagonizes VEGF and FGF2 stimulated angiogenesis by interfering with HS-dependent responses.19382872Pradhan S, Zhang C, Jia X, Carson DD, Witt R, Farach-Carson MCTissue engineering. Part APerlecan domain IV peptide stimulates salivary gland cell assembly in vitro. Tissue Eng Part A. 2009 Nov; 15(11):3309-20.Tissue Eng Part A2009-11-01T00:00:002009Perlecan domain IV peptide stimulates salivary gland cell assembly in vitro.19629389Kirn-Safran C, Farach-Carson MC, Carson DDCellular and molecular life sciences : CMLSMultifunctionality of extracellular and cell surface heparan sulfate proteoglycans. Cell Mol Life Sci. 2009 Nov; 66(21):3421-34.Cell Mol Life Sci2009-07-24T00:00:002009Multifunctionality of extracellular and cell surface heparan sulfate proteoglycans.22509318Lukianova-Hleb EY, Ren X, Constantinou PE, Danysh BP, Shenefelt DL, Carson DD, Farach-Carson MC, Kulchitsky VA, Wu X, Wagner DS, Lapotko DOPloS oneImproved cellular specificity of plasmonic nanobubbles versus nanoparticles in heterogeneous cell systems. PLoS One. 2012; 7(4):e34537.PLoS One2012-04-03T00:00:002012Improved cellular specificity of plasmonic nanobubbles versus nanoparticles in heterogeneous cell systems.14745237Gomes RR, Farach-Carson MC, Carson DDCells, tissues, organsPerlecan functions in chondrogenesis: insights from in vitro and in vivo models. Cells Tissues Organs. 2004; 176(1-3):79-86.Cells Tissues Organs2004-01-01T00:00:002004Perlecan functions in chondrogenesis: insights from in vitro and in vivo models.16283481Savor? C, Zhang C, Muir C, Liu R, Wyrwa J, Shu J, Zhau HE, Chung LW, Carson DD, Farach-Carson MCClinical & experimental metastasisPerlecan knockdown in metastatic prostate cancer cells reduces heparin-binding growth factor responses in vitro and tumor growth in vivo. Clin Exp Metastasis. 2005; 22(5):377-90.Clin Exp Metastasis2005-01-01T00:00:002005Perlecan knockdown in metastatic prostate cancer cells reduces heparin-binding growth factor responses in vitro and tumor growth in vivo.16466400Gomes RR, Joshi SS, Farach-Carson MC, Carson DDDifferentiation; research in biological diversityRibozyme-mediated perlecan knockdown impairs chondrogenic differentiation of C3H10T1/2 fibroblasts. Differentiation. 2006 Feb; 74(1):53-63.Differentiation2006-02-01T00:00:002006Ribozyme-mediated perlecan knockdown impairs chondrogenic differentiation of C3H10T1/2 fibroblasts.16835755Gomes RR, Van Kuppevelt TH, Farach-Carson MC, Carson DDHistochemistry and cell biologySpatiotemporal distribution of heparan sulfate epitopes during murine cartilage growth plate development. Histochem Cell Biol. 2006 Dec; 126(6):713-22.Histochem Cell Biol2006-07-12T00:00:002006Spatiotemporal distribution of heparan sulfate epitopes during murine cartilage growth plate development.20665531Zhang C, Soori M, Miles FL, Sikes RA, Carson DD, Chung LW, Farach-Carson MCThe ProstateParacrine factors produced by bone marrow stromal cells induce apoptosis and neuroendocrine differentiation in prostate cancer cells. Prostate. 2011 Feb 01; 71(2):157-67.Prostate2011-02-01T00:00:002011Paracrine factors produced by bone marrow stromal cells induce apoptosis and neuroendocrine differentiation in prostate cancer cells.true1Schlumberger Chair of Advanced Studies & Research; Professor of Biochemistry & Cell BiologySchlumberger Chair of Advanced Studies & Research; Professor of Biochemistry & Cell Biologytrue1Associate ProfessorAssociate ProfessorD005109Anatomy2935540.76281Extracellular MatrixD019812Chemicals & Drugs29540.956195Heparan Sulfate ProteoglycansD020219Physiology45670.952113ChondrogenesisD010064Physiology652770.824957Embryo ImplantationD006497Chemicals & Drugs26360.976838Heparitin SulfateNeurosurgeryDepartment of MedicineDepartment of Molecular & Cellular BiologyDepartment of NeurosurgeryMedicine-Cardiovascular ScienceMolecular & Cellular BiologyNeurosurgeryBaylor College of MedicineFREDERICKLANGFREDERICK LANG29.70706480000000-95.397162400000001037LANG, FREDERICKAdjunct ProfessorNIKOLAOSFRANGOGIANNISNIKOLAOS FRANGOGIANNIS29.70508570000000-95.401808700000001993FRANGOGIANNIS, NIKOLAOSAdjunct ProfessorFRANCESCODEMAYOFRANCESCO DEMAYO0.000000000000000.000000000000003030DEMAYO, FRANCESCOAdjunct ProfessorJOHNLYDONJOHN LYDON0.000000000000000.000000000000003271LYDON, JOHNAssociate Professor31351252Hubka KM, Carson DD, Harrington DA, Farach-Carson MCActa biomaterialiaPerlecan domain I gradients establish stable biomimetic heparin binding growth factor gradients for cell migration in hydrogels. Acta Biomater. 2019 10 01; 97:385-398.Acta Biomater2019-07-24T00:00:002019Perlecan domain I gradients establish stable biomimetic heparin binding growth factor gradients for cell migration in hydrogels.true1R & D Looney ProfessorR & D Looney Professortrue1Adjunct ProfessorAdjunct Professortrue1Adjunct ProfessorAdjunct ProfessorAuthorship 101807111Authorship 10180733Authorship 10180762Authorship 10180784Authorship 10180844Authorship 10183589Authorship 1018474526059746Engel BJ, Constantinou PE, Sablatura LK, Doty NJ, Carson DD, Farach-Carson MC, Harrington DA, Zarembinski TIAdvanced healthcare materialsMultilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures. Adv Healthc Mater. 2015 Aug 05; 4(11):1664-74.Adv Healthc Mater2015-06-09T00:00:002015Multilayered, Hyaluronic Acid-Based Hydrogel Formulations Suitable for Automated 3D High Throughput Drug Screening of Cancer-Stromal Cell Cocultures.32413029Brasil da Costa FH, Lewis MS, Truong A, Carson DD, Farach-Carson MCPloS oneSULF1 suppresses Wnt3A-driven growth of bone metastatic prostate cancer in perlecan-modified 3D cancer-stroma-macrophage triculture models. PLoS One. 2020; 15(5):e0230354.PLoS One2020-05-15T00:00:002020SULF1 suppresses Wnt3A-driven growth of bone metastatic prostate cancer in perlecan-modified 3D cancer-stroma-macrophage triculture models.22201009Constantinou PE, Danysh BP, Dharmaraj N, Carson DDExpert review of endocrinology & metabolismTransmembrane mucins as novel therapeutic targets. Expert Rev Endocrinol Metab. 2011 Nov; 6(6):835-848.Expert Rev Endocrinol Metab2011-11-01T00:00:002011Transmembrane mucins as novel therapeutic targets.26450494Constantinou PE, Morgado M, Carson DDAdvances in anatomy, embryology, and cell biologyTransmembrane Mucin Expression and Function in Embryo Implantation and Placentation. Adv Anat Embryol Cell Biol. 2015; 216:51-68.Adv Anat Embryol Cell Biol2015-01-01T00:00:002015Transmembrane Mucin Expression and Function in Embryo Implantation and Placentation.26918940Morgado M, Sutton MN, Simmons M, Warren CR, Lu Z, Constantinou PE, Liu J, Francis LL, Conlan RS, Bast RC, Carson DDOncotargetTumor necrosis factor-a and interferon-? stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NF?B. Oncotarget. 2016 Mar 22; 7(12):14871-84.Oncotarget2016-03-22T00:00:002016Tumor necrosis factor-a and interferon-? stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NF?B.33982426Pudakalakatti S, Enriquez JS, McCowan C, Ramezani S, Davis JS, Zacharias NM, Bourgeois D, Constantinou PE, Harrington DA, Carson D, Farach-Carson MC, Bhattacharya PKWiley interdisciplinary reviews. Nanomedicine and nanobiotechnologyHyperpolarized MRI with silicon micro and nanoparticles: Principles and applications. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021 11; 13(6):e1722.Wiley Interdiscip Rev Nanomed Nanobiotechnol2021-05-13T00:00:002021Hyperpolarized MRI with silicon micro and nanoparticles: Principles and applications.Authorship 1056468935937580Pudakalakatti S, Audia A, Mukhopadhyay A, Enriquez JS, Bourgeois D, Tayob N, Zacharias NM, Millward SW, Carson D, Farach-Carson MC, Lang FF, Heimberger AB, Bhat KP, Bhattacharya PKReports (MDPI)NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors. Reports (MDPI). 2021 Dec; 4(4).Reports (MDPI)2021-10-01T00:00:002021NMR Spectroscopy-Based Metabolomics of Platelets to Analyze Brain Tumors.true1Adjunct ProfessorAdjunct Professortrue1ProfessorProfessortrue1ProfessorProfessortrue1Associate ProfessorAssociate Professortrue1Assistant ProfessorAssistant Professortrue1ProfessorProfessor24001398Farach-Carson MC, Warren CR, Harrington DA, Carson DDMatrix biology : journal of the International Society for Matrix BiologyBorder patrol: insights into the unique role of perlecan/heparan sulfate proteoglycan 2 at cell and tissue borders. Matrix Biol. 2014 Feb; 34:64-79.Matrix Biol2013-08-31T00:00:002013Border patrol: insights into the unique role of perlecan/heparan sulfate proteoglycan 2 at cell and tissue borders.24700612Warren CR, Grindel BJ, Francis L, Carson DD, Farach-Carson MCJournal of cellular biochemistryTranscriptional activation by NF?B increases perlecan/HSPG2 expression in the desmoplastic prostate tumor microenvironment. J Cell Biochem. 2014 Jul; 115(7):1322-33.J Cell Biochem2014-07-01T00:00:002014Transcriptional activation by NF?B increases perlecan/HSPG2 expression in the desmoplastic prostate tumor microenvironment.