CINDYFARACH-CARSONCINDY FARACH-CARSON 8234FARACH-CARSON, CINDYperlecan, extracellular matrix, bone metastasis, prostate cancer, tumor microenvironment, tissue engineering, salivary glandR & D Looney Professorprns:awardConferredByaward conferred byprns:coAuthorOfcoauthor ofFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:similarTosimilar toprns:sortOrdersort orderprns:startDatestart dateprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierAddressvivo:address1address line 1vivo:addressCitycityvivo:addressPostalCodepostal codevivo:addressStatestate or provincevivo:authorInAuthorshipselected publicationsvivo:authorRankauthor rank in publicationAuthorshipvivo:awardOrHonorawards and honorsAward or Honor ReceiptDepartmentDivisionvivo:freetextKeywordkeywordsvivo:hasResearchArearesearch areasvivo:hrJobTitleHR job titleInformation Resourcevivo:linkedAuthorlinked authorvivo:linkedInformationResourcelinked information resourcevivo:mailingAddressmailing addressvivo:personInPositionpositionsPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlerdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson6100 Main StreetHouston77005TXBioSciences at RiceRice University2.270740.00177599405research areas0.4805110.03850073coauthor of11.80973.0700960similar to1170selected publicationsDANIELCARSONDANIEL CARSON 8233CARSON, DANIELSchlumberger Chair of Advanced Studies & Research; Professor of Biochemistry & Cell BiologyAuthorship 1576447Authorship 1577758Authorship 1580191Anesthesiology & PeriOperative MedicineGenitourinary Medical OncologyTranslational Molecular PathologyMD AndersonPATRICIATRONCOSOPATRICIA TRONCOSO8504TRONCOSO, PATRICIAProfessorHUI-LINPANHUI-LIN PAN9317PAN, HUI-LINProfessorSUE-HWALINSUE-HWA LIN8429LIN, SUE-HWAProfessorCHRISTOPHER JLOGOTHETISCHRISTOPHER J LOGOTHETIS8480LOGOTHETIS, CHRISTOPHER JProfessor7925641Yue TL, McKenna PJ, Ohlstein EH, Farach-Carson MC, Butler WT, Johanson K, McDevitt P, Feuerstein GZ, Stadel JMExperimental cell researchOsteopontin-stimulated vascular smooth muscle cell migration is mediated by beta 3 integrin. Exp Cell Res. 1994 Oct; 214(2):459-64.Exp Cell Res1994-10-01T00:00:001994Osteopontin-stimulated vascular smooth muscle cell migration is mediated by beta 3 integrin.FLORENTELEFTERIOUFLORENT ELEFTERIOU10702ELEFTERIOU, FLORENTProfessor7794128Pinero GJ, Farach-Carson MC, Devoll RE, Aubin JE, Brunn JC, Butler WTArchives of oral biologyBone matrix proteins in osteogenesis and remodelling in the neonatal rat mandible as studied by immunolocalization of osteopontin, bone sialoprotein, alpha 2HS-glycoprotein and alkaline phosphatase. Arch Oral Biol. 1995 Feb; 40(2):145-55.Arch Oral Biol1995-02-01T00:00:001995Bone matrix proteins in osteogenesis and remodelling in the neonatal rat mandible as studied by immunolocalization of osteopontin, bone sialoprotein, alpha 2HS-glycoprotein and alkaline phosphatase.8304052van Dijk S, D'Errico JA, Somerman MJ, Farach-Carson MC, Butler WTJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchEvidence that a non-RGD domain in rat osteopontin is involved in cell attachment. J Bone Miner Res. 1993 Dec; 8(12):1499-506.J Bone Miner Res1993-12-01T00:00:001993Evidence that a non-RGD domain in rat osteopontin is involved in cell attachment.8475798McKee MD, Farach-Carson MC, Butler WT, Hauschka PV, Nanci AJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchUltrastructural immunolocalization of noncollagenous (osteopontin and osteocalcin) and plasma (albumin and alpha 2HS-glycoprotein) proteins in rat bone. J Bone Miner Res. 1993 Apr; 8(4):485-96.J Bone Miner Res1993-04-01T00:00:001993Ultrastructural immunolocalization of noncollagenous (osteopontin and osteocalcin) and plasma (albumin and alpha 2HS-glycoprotein) proteins in rat bone.9075637Devoll RE, Pinero GJ, Appelbaum ER, Dul E, Troncoso P, Butler WT, Farach-Carson MCCalcified tissue internationalImproved immunohistochemical staining of osteopontin (OPN) in paraffin-embedded archival bone specimens following antigen retrieval: anti-human OPN antibody recognizes multiple molecular forms. Calcif Tissue Int. 1997 Apr; 60(4):380-6.Calcif Tissue Int1997-04-01T00:00:001997Improved immunohistochemical staining of osteopontin (OPN) in paraffin-embedded archival bone specimens following antigen retrieval: anti-human OPN antibody recognizes multiple molecular forms.8079659Bronckers AL, Farach-Carson MC, Van Waveren E, Butler WTJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchImmunolocalization of osteopontin, osteocalcin, and dentin sialoprotein during dental root formation and early cementogenesis in the rat. J Bone Miner Res. 1994 Jun; 9(6):833-41.J Bone Miner Res1994-06-01T00:00:001994Immunolocalization of osteopontin, osteocalcin, and dentin sialoprotein during dental root formation and early cementogenesis in the rat.9792712Safran JB, Butler WT, Farach-Carson MCThe Journal of biological chemistryModulation of osteopontin post-translational state by 1, 25-(OH)2-vitamin D3. Dependence on Ca2+ influx. J Biol Chem. 1998 Nov 06; 273(45):29935-41.J Biol Chem1998-11-06T00:00:001998Modulation of osteopontin post-translational state by 1, 25-(OH)2-vitamin D3. Dependence on Ca2+ influx.10069535Devoll RE, Li W, Woods KV, Pinero GJ, Butler WT, Farach-Carson MC, Happonen RPJournal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral PathologyOsteopontin (OPN) distribution in premalignant and malignant lesions of oral epithelium and expression in cell lines derived from squamous cell carcinoma of the oral cavity. J Oral Pathol Med. 1999 Mar; 28(3):97-101.J Oral Pathol Med1999-03-01T00:00:001999Osteopontin (OPN) distribution in premalignant and malignant lesions of oral epithelium and expression in cell lines derived from squamous cell carcinoma of the oral cavity.83R & D Looney Professor86Schlumberger Chair of Advanced Studies & Research; Professor of Biochemistry & Cell Biology8486670Ross FP, Chappel J, Alvarez JI, Sander D, Butler WT, Farach-Carson MC, Mintz KA, Robey PG, Teitelbaum SL, Cheresh DAThe Journal of biological chemistryInteractions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption. J Biol Chem. 1993 May 05; 268(13):9901-7.J Biol Chem1993-05-05T00:00:001993Interactions between the bone matrix proteins osteopontin and bone sialoprotein and the osteoclast integrin alpha v beta 3 potentiate bone resorption.Authorship 3153085Authorship 3153095Authorship 3153106Authorship 3153112Authorship 3153122Authorship 3153132Authorship 3153143Authorship 3153153Authorship 3153162Authorship 3153173Authorship 3153184Authorship 3153191Authorship 3153206Authorship 3153212Authorship 3153224Authorship 3153236Authorship 3153243Authorship 3153254Authorship 31532611Authorship 3153271Authorship 3153282Authorship 3153296Authorship 3153304Authorship 3153313Authorship 3153321Authorship 3153333Authorship 3153344Authorship 3153354Authorship 31533612Authorship 3153372Authorship 3153382Authorship 3153395Authorship 3153402Authorship 3153413Authorship 3153421Authorship 3153431Authorship 3153443Authorship 3153453Authorship 3153462Authorship 3153476Authorship 3153482Authorship 3153498Authorship 3153506Authorship 3153516Authorship 31535210Authorship 3153534Authorship 3153544Authorship 3153556Authorship 3153561Authorship 3153573Authorship 3153581Authorship 3153594Authorship 3153601Authorship 3153617Authorship 3153621Authorship 3153632Authorship 3153644Authorship 3153656Authorship 3153661Authorship 3153674Authorship 3153682Authorship 3153694Authorship 3153701Authorship 3153718Authorship 3153721Authorship 3153732Authorship 3153742Rice University2016Presidential Mentoring AwardAAAS2010AAAS Member; Biological Sciences 1537006Farach-Carson MC, Wright GC, Butler WTBone and mineralImproved binding of acidic bone matrix proteins to cationized filters during solid phase assays. Bone Miner. 1992 Jan; 16(1):1-9.Bone Miner1992-01-01T00:00:001992Improved binding of acidic bone matrix proteins to cationized filters during solid phase assays.74Professor78Professor Emeritus1552175D'Souza RN, Bronckers AL, Happonen RP, Doga DA, Farach-Carson MC, Butler WTThe journal of histochemistry and cytochemistry : official journal of the Histochemistry SocietyDevelopmental expression of a 53 KD dentin sialoprotein in rat tooth organs. J Histochem Cytochem. 1992 Mar; 40(3):359-66.J Histochem Cytochem1992-03-01T00:00:001992Developmental expression of a 53 KD dentin sialoprotein in rat tooth organs.2065215Mizuno M, Farach-Carson MC, Pinero GJ, Fujisawa R, Brunn JC, Seyer JM, Bousfield GR, Mark MP, Butler WTBone and mineralIdentification of the rat bone 60K acidic glycoprotein as alpha 2HS-glycoprotein. Bone Miner. 1991 Apr; 13(1):1-21.Bone Miner1991-04-01T00:00:001991Identification of the rat bone 60K acidic glycoprotein as alpha 2HS-glycoprotein.2228315Chan JC, Scanlon M, Denhardt DT, Singh K, Mukherjee BB, Farach-Carson MC, Butler WTInternational journal of cancerImmunochemical comparison of transformation-associated protein and secreted phosphoprotein. Int J Cancer. 1990 Nov 15; 46(5):864-70.Int J Cancer1990-11-15T00:00:001990Immunochemical comparison of transformation-associated protein and secreted phosphoprotein.23832678Pradhan-Bhatt S, Harrington DA, Duncan RL, Farach-Carson MC, Jia X, Witt RLThe LaryngoscopeA novel in vivo model for evaluating functional restoration of a tissue-engineered salivary gland. Laryngoscope. 2014 Feb; 124(2):456-61.Laryngoscope2013-08-06T00:00:002013A novel in vivo model for evaluating functional restoration of a tissue-engineered salivary gland.1442202Ritter NM, Farach-Carson MC, Butler WTJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchEvidence for the formation of a complex between osteopontin and osteocalcin. J Bone Miner Res. 1992 Aug; 7(8):877-85.J Bone Miner Res1992-08-01T00:00:001992Evidence for the formation of a complex between osteopontin and osteocalcin.1484502Butler WT, Bhown M, Brunn JC, D'Souza RN, Farach-Carson MC, Happonen RP, Schrohenloher RE, Seyer JM, Somerman MJ, Foster RAMatrix (Stuttgart, Germany)Isolation, characterization and immunolocalization of a 53-kDal dentin sialoprotein (DSP). Matrix. 1992 Nov; 12(5):343-51.Matrix1992-11-01T00:00:001992Isolation, characterization and immunolocalization of a 53-kDal dentin sialoprotein (DSP).true1Schlumberger Chair of Advanced Studies & Research; Professor of Biochemistry & Cell BiologySchlumberger Chair of Advanced Studies & Research; Professor of Biochemistry & Cell BiologyD010006Anatomy1553650.822287OsteoblastsD019812Chemicals & Drugs29540.956211Heparan Sulfate ProteoglycansD012795Chemicals & Drugs881510.958543SialoglycoproteinsD002117Chemicals & Drugs661270.934687CalcitriolD002118Chemicals & Drugs52915430.610901Calcium10352025French MM, Smith SE, Akanbi K, Sanford T, Hecht J, Farach-Carson MC, Carson DDThe Journal of cell biologyExpression of the heparan sulfate proteoglycan, perlecan, during mouse embryogenesis and perlecan chondrogenic activity in vitro. J Cell Biol. 1999 May 31; 145(5):1103-15.J Cell Biol1999-05-31T00:00:001999Expression of the heparan sulfate proteoglycan, perlecan, during mouse embryogenesis and perlecan chondrogenic activity in vitro.22419946Xu X, Jha AK, Harrington DA, Farach-Carson MC, Jia XSoft matterHyaluronic Acid-Based Hydrogels: from a Natural Polysaccharide to Complex Networks. Soft Matter. 2012; 8(12):3280-3294.Soft Matter2012-01-01T00:00:002012Hyaluronic Acid-Based Hydrogels: from a Natural Polysaccharide to Complex Networks.21804947Lukianova-Hleb EY, Oginsky AO, Shenefelt DL, Drezek RA, Hafner JH, Farach-Carson MC, Lapotko DOJournal of nanomedicine & nanotechnologyRainbow Plasmonic Nanobubbles: Synergistic Activation of Gold Nanoparticle Clusters. J Nanomed Nanotechnol. 2011 Jan 01; 2(104):1-8.J Nanomed Nanotechnol2011-01-01T00:00:002011Rainbow Plasmonic Nanobubbles: Synergistic Activation of Gold Nanoparticle Clusters.20936090Jha AK, Malik MS, Farach-Carson MC, Duncan RL, Jia XSoft matterHierarchically structured, hyaluronic acid-based hydrogel matrices via the covalent integration of microgels into macroscopic networks. Soft Matter. 2010 Jun 15; 6(20):5045-5055.Soft Matter2010-06-15T00:00:002010Hierarchically structured, hyaluronic acid-based hydrogel matrices via the covalent integration of microgels into macroscopic networks.20594408Wang X, Gurski LA, Zhong S, Xu X, Pochan DJ, Farach-Carson MC, Jia XJournal of biomaterials science. Polymer editionAmphiphilic block co-polyesters bearing pendant cyclic ketal groups as nanocarriers for controlled release of camptothecin. J Biomater Sci Polym Ed. 2011; 22(10):1275-98.J Biomater Sci Polym Ed2011-01-01T00:00:002011Amphiphilic block co-polyesters bearing pendant cyclic ketal groups as nanocarriers for controlled release of camptothecin.19414073O'Connor RD, Zayzafoon M, Farach-Carson MC, Schanen NCBoneMecp2 deficiency decreases bone formation and reduces bone volume in a rodent model of Rett syndrome. Bone. 2009 Aug; 45(2):346-56.Bone2009-05-03T00:00:002009Mecp2 deficiency decreases bone formation and reduces bone volume in a rodent model of Rett syndrome.18589009Brown AJ, Alicknavitch M, D'Souza SS, Daikoku T, Kirn-Safran CB, Marchetti D, Carson DD, Farach-Carson MCBoneHeparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation. Bone. 2008 Oct; 43(4):689-99.Bone2008-06-06T00:00:002008Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation.16507112Datta MW, Hernandez AM, Schlicht MJ, Kahler AJ, DeGueme AM, Dhir R, Shah RB, Farach-Carson C, Barrett A, Datta SMolecular cancerPerlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway. Mol Cancer. 2006 Mar 01; 5:9.Mol Cancer2006-03-01T00:00:002006Perlecan, a candidate gene for the CAPB locus, regulates prostate cancer cell growth via the Sonic Hedgehog pathway.15758379Gomes R, Kirn-Safran C, Farach-Carson MC, Carson DDJournal of musculoskeletal & neuronal interactionsPerlecan: an important component of the cartilage pericellular matrix. J Musculoskelet Neuronal Interact. 2002 Dec; 2(6):511-6.J Musculoskelet Neuronal Interact2002-12-01T00:00:002002Perlecan: an important component of the cartilage pericellular matrix.15738663Yang WD, Gomes RR, Alicknavitch M, Farach-Carson MC, Carson DDTissue engineeringPerlecan domain I promotes fibroblast growth factor 2 delivery in collagen I fibril scaffolds. Tissue Eng. 2005 Jan-Feb; 11(1-2):76-89.Tissue Eng2005-01-01T00:00:002005Perlecan domain I promotes fibroblast growth factor 2 delivery in collagen I fibril scaffolds.15123837Nemere I, Farach-Carson MC, Rohe B, Sterling TM, Norman AW, Boyan BD, Safford SEProceedings of the National Academy of Sciences of the United States of AmericaRibozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells. Proc Natl Acad Sci U S A. 2004 May 11; 101(19):7392-7.Proc Natl Acad Sci U S A2004-04-29T00:00:002004Ribozyme knockdown functionally links a 1,25(OH)2D3 membrane binding protein (1,25D3-MARRS) and phosphate uptake in intestinal cells.12958687Bergh JJ, Shao Y, Akanbi K, Farach-Carson MCCalcified tissue internationalRodent osteoblastic cells express voltage-sensitive calcium channels lacking a gamma subunit. Calcif Tissue Int. 2003 Nov; 73(5):502-10.Calcif Tissue Int2003-09-10T00:00:002003Rodent osteoblastic cells express voltage-sensitive calcium channels lacking a gamma subunit.12952197Gomes RR, Farach Carson MC, Carson DDConnective tissue researchPerlecan-stimulated nodules undergo chondrogenic maturation in response to rhBMP-2 treatment in vitro. Connect Tissue Res. 2003; 44 Suppl 1:196-201.Connect Tissue Res2003-01-01T00:00:002003Perlecan-stimulated nodules undergo chondrogenic maturation in response to rhBMP-2 treatment in vitro.12528991Farach-Carson MC, Nemere ICurrent drug targetsMembrane receptors for vitamin D steroid hormones: potential new drug targets. Curr Drug Targets. 2003 Jan; 4(1):67-76.Curr Drug Targets2003-01-01T00:00:002003Membrane receptors for vitamin D steroid hormones: potential new drug targets.12097308Ta TV, Baraniak D, Julian J, Korostoff J, Carson DD, Farach-Carson MCJournal of dental researchHeparan sulfate interacting protein (HIP/L29) negatively regulates growth responses to basic fibroblast growth factor in gingival fibroblasts. J Dent Res. 2002 Apr; 81(4):247-52.J Dent Res2002-04-01T00:00:002002Heparan sulfate interacting protein (HIP/L29) negatively regulates growth responses to basic fibroblast growth factor in gingival fibroblasts.11691583Kiefer JA, Farach-Carson MCMatrix biology : journal of the International Society for Matrix BiologyType I collagen-mediated proliferation of PC3 prostate carcinoma cell line: implications for enhanced growth in the bone microenvironment. Matrix Biol. 2001 Nov; 20(7):429-37.Matrix Biol2001-11-01T00:00:002001Type I collagen-mediated proliferation of PC3 prostate carcinoma cell line: implications for enhanced growth in the bone microenvironment.11557366Li W, Farach-Carson MCBoneParathyroid hormone-stimulated resorption in calvaria cultured in serum-free medium is enhanced by the calcium-mobilizing activity of 1,25-dihydroxyvitamin D(3). Bone. 2001 Sep; 29(3):231-5.Bone2001-09-01T00:00:002001Parathyroid hormone-stimulated resorption in calvaria cultured in serum-free medium is enhanced by the calcium-mobilizing activity of 1,25-dihydroxyvitamin D(3).11243469Edlund M, Miyamoto T, Sikes RA, Ogle R, Laurie GW, Farach-Carson MC, Otey CA, Zhau HE, Chung LWCell growth & differentiation : the molecular biology journal of the American Association for Cancer ResearchIntegrin expression and usage by prostate cancer cell lines on laminin substrata. Cell Growth Differ. 2001 Feb; 12(2):99-107.Cell Growth Differ2001-02-01T00:00:002001Integrin expression and usage by prostate cancer cell lines on laminin substrata.11179744Farach-Carson MCSteroidsBioactive analogs that simulate subsets of biological activities of 1alpha,25(OH)(2)D(3) in osteoblasts. Steroids. 2001 Mar-May; 66(3-5):357-61.Steroids2001-03-01T00:00:002001Bioactive analogs that simulate subsets of biological activities of 1alpha,25(OH)(2)D(3) in osteoblasts.10873570Liu R, Xu Y, Farach-Carson MC, Vogel JJ, Karin NJBiochemical and biophysical research communications1,25 dihydroxyvitamin D(3) activates sphingomyelin turnover in ROS17/2.8 osteosarcoma cells without sphingolipid-induced changes in cytosolic Ca(2+). Biochem Biophys Res Commun. 2000 Jun 24; 273(1):95-100.Biochem Biophys Res Commun2000-06-24T00:00:0020001,25 dihydroxyvitamin D(3) activates sphingomyelin turnover in ROS17/2.8 osteosarcoma cells without sphingolipid-induced changes in cytosolic Ca(2+).10726209Lecrone V, Li W, Devoll RE, Logothetis C, Farach-Carson MCCell calciumCalcium signals in prostate cancer cells: specific activation by bone-matrix proteins. Cell Calcium. 2000 Jan; 27(1):35-42.Cell Calcium2000-01-01T00:00:002000Calcium signals in prostate cancer cells: specific activation by bone-matrix proteins.10722713Liu R, Li W, Karin NJ, Bergh JJ, Adler-Storthz K, Farach-Carson MCThe Journal of biological chemistryRibozyme ablation demonstrates that the cardiac subtype of the voltage-sensitive calcium channel is the molecular transducer of 1, 25-dihydroxyvitamin D(3)-stimulated calcium influx in osteoblastic cells. J Biol Chem. 2000 Mar 24; 275(12):8711-8.J Biol Chem2000-03-24T00:00:002000Ribozyme ablation demonstrates that the cardiac subtype of the voltage-sensitive calcium channel is the molecular transducer of 1, 25-dihydroxyvitamin D(3)-stimulated calcium influx in osteoblastic cells.10473115Thalmann GN, Sikes RA, Devoll RE, Kiefer JA, Markwalder R, Klima I, Farach-Carson CM, Studer UE, Chung LWClinical cancer research : an official journal of the American Association for Cancer ResearchOsteopontin: possible role in prostate cancer progression. Clin Cancer Res. 1999 Aug; 5(8):2271-7.Clin Cancer Res1999-08-01T00:00:001999Osteopontin: possible role in prostate cancer progression.PathologyDepartment of Orthopedic SurgeryDepartment of Molecular & Cellular BiologyMolecular & Cellular BiologyMolecular Physiology & BiophysicsOrthopedic SurgeryBaylor College of MedicineNANCYWEIGELNANCY WEIGEL0.000000000000000.000000000000002552WEIGEL, NANCYProfessor EmeritusXANDERWEHRENSXANDER WEHRENS0.000000000000000.00000000000000964WEHRENS, XANDERProfessortrue1R & D Looney ProfessorR & D Looney Professortrue1ProfessorProfessortrue1ProfessorProfessorDepartment of Integrative Physiology24447463Xu X, Sabanayagam CR, Harrington DA, Farach-Carson MC, Jia XBiomaterialsA hydrogel-based tumor model for the evaluation of nanoparticle-based cancer therapeutics. Biomaterials. 2014 Mar; 35(10):3319-30.Biomaterials2014-01-18T00:00:002014A hydrogel-based tumor model for the evaluation of nanoparticle-based cancer therapeutics.24115222Wang B, Lai X, Price C, Thompson WR, Li W, Quabili TR, Tseng WJ, Liu XS, Zhang H, Pan J, Kirn-Safran CB, Farach-Carson MC, Wang LJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral ResearchPerlecan-containing pericellular matrix regulates solute transport and mechanosensing within the osteocyte lacunar-canalicular system. J Bone Miner Res. 2014 Apr; 29(4):878-91.J Bone Miner Res2014-04-01T00:00:002014Perlecan-containing pericellular matrix regulates solute transport and mechanosensing within the osteocyte lacunar-canalicular system.9280067Norman AW, Okamura WH, Hammond MW, Bishop JE, Dormanen MC, Bouillon R, van Baelen H, Ridall AL, Daane E, Khoury R, Farach-Carson MCMolecular endocrinology (Baltimore, Md.)Comparison of 6-s-cis- and 6-s-trans-locked analogs of 1alpha,25-dihydroxyvitamin D3 indicates that the 6-s-cis conformation is preferred for rapid nongenomic biological responses and that neither 6-s-cis- nor 6-s-trans-locked analogs are preferred for genomic biological responses. Mol Endocrinol. 1997 Sep; 11(10):1518-31.Mol Endocrinol1997-09-01T00:00:001997Comparison of 6-s-cis- and 6-s-trans-locked analogs of 1alpha,25-dihydroxyvitamin D3 indicates that the 6-s-cis conformation is preferred for rapid nongenomic biological responses and that neither 6-s-cis- nor 6-s-trans-locked analogs are preferred for genomic biological responses.9316451Li W, Duncan RL, Karin NJ, Farach-Carson MCThe American journal of physiology1,25 (OH)2D3 enhances PTH-induced Ca2+ transients in preosteoblasts by activating L-type Ca2+ channels. Am J Physiol. 1997 Sep; 273(3 Pt 1):E599-605.Am J Physiol1997-09-01T00:00:0019971,25 (OH)2D3 enhances PTH-induced Ca2+ transients in preosteoblasts by activating L-type Ca2+ channels.9330292Meszaros JG, Farach-Carson MCMethods in enzymologyAssay of direct effect of 1,25-dihydroxyvitamin D3 on calcium ion influx into cultured osteoblasts. Methods Enzymol. 1997; 282:236-43.Methods Enzymol1997-01-01T00:00:001997Assay of direct effect of 1,25-dihydroxyvitamin D3 on calcium ion influx into cultured osteoblasts.9594755Snyder WR, Hoover J, Khoury R, Farach-Carson MCJournal of endodonticsEffect of agents used in perforation repair on osteoblastic cells. J Endod. 1997 Mar; 23(3):158-61.J Endod1997-03-01T00:00:001997Effect of agents used in perforation repair on osteoblastic cells.9084649Meszaros JG, Karin NJ, Farach-Carson MCConnective tissue researchVoltage-sensitive calcium channels in osteoblasts: mediators of plasma membrane signalling events. Connect Tissue Res. 1996; 35(1-4):107-11.Connect Tissue Res1996-01-01T00:00:001996Voltage-sensitive calcium channels in osteoblasts: mediators of plasma membrane signalling events.8955142Meszaros JG, Karin NJ, Akanbi K, Farach-Carson MCThe Journal of biological chemistryDown-regulation of L-type Ca2+ channel transcript levels by 1,25-dihyroxyvitamin D3. Osteoblastic cells express L-type alpha1C Ca2+ channel isoforms. J Biol Chem. 1996 Dec 20; 271(51):32981-5.J Biol Chem1996-12-20T00:00:001996Down-regulation of L-type Ca2+ channel transcript levels by 1,25-dihyroxyvitamin D3. Osteoblastic cells express L-type alpha1C Ca2+ channel isoforms.8603033Norman AW, Bishop JE, Collins ED, Seo EG, Satchell DP, Dormanen MC, Zanello SB, Farach-Carson MC, Bouillon R, Okamura WHThe Journal of steroid biochemistry and molecular biologyDiffering shapes of 1 alpha,25-dihydroxyvitamin D3 function as ligands for the D-binding protein, nuclear receptor and membrane receptor: a status report. J Steroid Biochem Mol Biol. 1996 Jan; 56(1-6 Spec No):13-22.J Steroid Biochem Mol Biol1996-01-01T00:00:001996Differing shapes of 1 alpha,25-dihydroxyvitamin D3 function as ligands for the D-binding protein, nuclear receptor and membrane receptor: a status report.7677781Liu R, Farach-Carson MC, Karin NJBiochemical and biophysical research communicationsEffects of sphingosine derivatives on MC3T3-E1 pre-osteoblasts: psychosine elicits release of calcium from intracellualr stores. Biochem Biophys Res Commun. 1995 Sep 14; 214(2):676-84.Biochem Biophys Res Commun1995-09-14T00:00:001995Effects of sphingosine derivatives on MC3T3-E1 pre-osteoblasts: psychosine elicits release of calcium from intracellualr stores.7782930Khoury RS, Weber J, Farach-Carson MCThe Journal of nutritionVitamin D metabolites modulate osteoblast activity by Ca+2 influx-independent genomic and Ca+2 influx-dependent nongenomic pathways. J Nutr. 1995 06; 125(6 Suppl):1699S-1703S.J Nutr1995-06-01T00:00:001995Vitamin D metabolites modulate osteoblast activity by Ca+2 influx-independent genomic and Ca+2 influx-dependent nongenomic pathways.7988430Khoury R, Ridall AL, Norman AW, Farach-Carson MCEndocrinologyTarget gene activation by 1,25-dihydroxyvitamin D3 in osteosarcoma cells is independent of calcium influx. Endocrinology. 1994 Dec; 135(6):2446-53.Endocrinology1994-12-01T00:00:001994Target gene activation by 1,25-dihydroxyvitamin D3 in osteosarcoma cells is independent of calcium influx.8238551Farach-Carson MC, Abe J, Nishii Y, Khoury R, Wright GC, Norman AWThe American journal of physiology22-Oxacalcitriol: dissection of 1,25(OH)2D3 receptor-mediated and Ca2+ entry-stimulating pathways. Am J Physiol. 1993 Nov; 265(5 Pt 2):F705-11.Am J Physiol1993-11-01T00:00:00199322-Oxacalcitriol: dissection of 1,25(OH)2D3 receptor-mediated and Ca2+ entry-stimulating pathways.8397195Norman AW, Bouillon R, Farach-Carson MC, Bishop JE, Zhou LX, Nemere I, Zhao J, Muralidharan KR, Okamura WHThe Journal of biological chemistryDemonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3. J Biol Chem. 1993 Sep 25; 268(27):20022-30.J Biol Chem1993-09-25T00:00:001993Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.8390978Norman AW, Okamura WH, Farach-Carson MC, Allewaert K, Branisteanu D, Nemere I, Muralidharan KR, Bouillon RThe Journal of biological chemistryStructure-function studies of 1,25-dihydroxyvitamin D3 and the vitamin D endocrine system. 1,25-dihydroxy-pentadeuterio-previtamin D3 (as a 6-s-cis analog) stimulates nongenomic but not genomic biological responses. J Biol Chem. 1993 Jul 05; 268(19):13811-9.J Biol Chem1993-07-05T00:00:001993Structure-function studies of 1,25-dihydroxyvitamin D3 and the vitamin D endocrine system. 1,25-dihydroxy-pentadeuterio-previtamin D3 (as a 6-s-cis analog) stimulates nongenomic but not genomic biological responses.1314073Norman AW, Nemere I, Zhou LX, Bishop JE, Lowe KE, Maiyar AC, Collins ED, Taoka T, Sergeev I, Farach-Carson MCThe Journal of steroid biochemistry and molecular biology1,25(OH)2-vitamin D3, a steroid hormone that produces biologic effects via both genomic and nongenomic pathways. J Steroid Biochem Mol Biol. 1992 Mar; 41(3-8):231-40.J Steroid Biochem Mol Biol1992-03-01T00:00:0019921,25(OH)2-vitamin D3, a steroid hormone that produces biologic effects via both genomic and nongenomic pathways.1655387Farach-Carson MC, Sergeev I, Norman AWEndocrinologyNongenomic actions of 1,25-dihydroxyvitamin D3 in rat osteosarcoma cells: structure-function studies using ligand analogs. Endocrinology. 1991 Oct; 129(4):1876-84.Endocrinology1991-10-01T00:00:001991Nongenomic actions of 1,25-dihydroxyvitamin D3 in rat osteosarcoma cells: structure-function studies using ligand analogs.2475510Farach-Carson MC, Carson DD, Collier JL, Lennarz WJ, Park HR, Wright GCThe Journal of cell biologyA calcium-binding, asparagine-linked oligosaccharide is involved in skeleton formation in the sea urchin embryo. J Cell Biol. 1989 Sep; 109(3):1289-99.J Cell Biol1989-09-01T00:00:001989A calcium-binding, asparagine-linked oligosaccharide is involved in skeleton formation in the sea urchin embryo.2845251Caffrey JM, Farach MCMolecular pharmacologyA monoclonal antibody specifically modulates dihydropyridine-sensitive calcium current in BC3H1 myocytes. Mol Pharmacol. 1988 Oct; 34(4):518-26.Mol Pharmacol1988-10-01T00:00:001988A monoclonal antibody specifically modulates dihydropyridine-sensitive calcium current in BC3H1 myocytes.3179390Farach MC, Tang JP, Decker GL, Carson DDBiology of reproductionDifferential effects of p-nitrophenyl-D-xylosides on mouse blastocysts and uterine epithelial cells. Biol Reprod. 1988 Sep; 39(2):443-55.Biol Reprod1988-09-01T00:00:001988Differential effects of p-nitrophenyl-D-xylosides on mouse blastocysts and uterine epithelial cells.2958379Farach MC, Tang JP, Decker GL, Carson DDDevelopmental biologyHeparin/heparan sulfate is involved in attachment and spreading of mouse embryos in vitro. Dev Biol. 1987 Oct; 123(2):401-10.Dev Biol1987-10-01T00:00:001987Heparin/heparan sulfate is involved in attachment and spreading of mouse embryos in vitro.3297856Farach MC, Valdizan M, Park HR, Decker GL, Lennarz WJDevelopmental biologyDevelopmental expression of a cell-surface protein involved in calcium uptake and skeleton formation in sea urchin embryos. Dev Biol. 1987 Aug; 122(2):320-31.Dev Biol1987-08-01T00:00:001987Developmental expression of a cell-surface protein involved in calcium uptake and skeleton formation in sea urchin embryos.3986913Carson DD, Farach MC, Earles DS, Decker GL, Lennarz WJCellA monoclonal antibody inhibits calcium accumulation and skeleton formation in cultured embryonic cells of the sea urchin. Cell. 1985 Jun; 41(2):639-48.Cell1985-06-01T00:00:001985A monoclonal antibody inhibits calcium accumulation and skeleton formation in cultured embryonic cells of the sea urchin.19431543Martinez-Carrion M, Gonzalez-Ros JM, Mattingly JR, Ferragut JA, Farach MC, Donnelly DBiophysical journalFluorescence probes for the study of acetylcholine receptor function. Biophys J. 1984 Jan; 45(1):141-3.Biophys J1984-01-01T00:00:001984Fluorescence probes for the study of acetylcholine receptor function.6833247Farach MC, Martinez-Carrion MThe Journal of biological chemistryA differential scanning calorimetry study of acetylcholine receptor-rich membranes from Torpedo californica. J Biol Chem. 1983 Apr 10; 258(7):4166-70.J Biol Chem1983-04-10T00:00:001983A differential scanning calorimetry study of acetylcholine receptor-rich membranes from Torpedo californica.6615803Gonzalez-Ros JM, Farach MC, Martinez-Carrion MBiochemistryLigand-induced effects at regions of acetylcholine receptor accessible to membrane lipids. Biochemistry. 1983 Aug 02; 22(16):3807-11.Biochemistry1983-08-02T00:00:001983Ligand-induced effects at regions of acetylcholine receptor accessible to membrane lipids.6625612Soler G, Farach MC, Farach HA, Mattingly JR, Martinez-Carrion MArchives of biochemistry and biophysicsReductive methylation as a probe of the heat-labile alpha-bungarotoxin-acetylcholine receptor membrane complex: evidence for surface interactions. Arch Biochem Biophys. 1983 Sep; 225(2):872-8.Arch Biochem Biophys1983-09-01T00:00:001983Reductive methylation as a probe of the heat-labile alpha-bungarotoxin-acetylcholine receptor membrane complex: evidence for surface interactions.7175977Mong FS, Farach MC, Martinez-Carrion MJournal of neuroscience researchPattern of acetylcholine receptor activity during regeneration of free muscle transplants of rats. J Neurosci Res. 1982; 8(1):27-33.J Neurosci Res1982-01-01T00:00:001982Pattern of acetylcholine receptor activity during regeneration of free muscle transplants of rats.7081993Farach MC, Mihovilovic M, Paraschos A, Martinez-Carrion MArchives of biochemistry and biophysicsEffect of anti-acetylcholine receptor Fab fragments from goats on functional membrane-bound receptor. Arch Biochem Biophys. 1982 Mar; 214(1):140-54.Arch Biochem Biophys1982-03-01T00:00:001982Effect of anti-acetylcholine receptor Fab fragments from goats on functional membrane-bound receptor.7225389Gonzalez-Ros JM, Paraschos A, Farach MC, Martinez-Carrion MBiochimica et biophysica actaCharacterization of acetylcholine receptor isolated from Torpedo californica electroplax through the use of an easily removable detergent, beta-D-octylglucopyranoside. Biochim Biophys Acta. 1981 May 06; 643(2):407-20.Biochim Biophys Acta1981-05-06T00:00:001981Characterization of acetylcholine receptor isolated from Torpedo californica electroplax through the use of an easily removable detergent, beta-D-octylglucopyranoside.true1Professor EmeritusProfessor Emeritustrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessortrue1ProfessorProfessor24001398Farach-Carson MC, Warren CR, Harrington DA, Carson DDMatrix biology : journal of the International Society for Matrix BiologyBorder patrol: insights into the unique role of perlecan/heparan sulfate proteoglycan 2 at cell and tissue borders. Matrix Biol. 2014 Feb; 34:64-79.Matrix Biol2013-08-31T00:00:002013Border patrol: insights into the unique role of perlecan/heparan sulfate proteoglycan 2 at cell and tissue borders.