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TAHIR HUSSAIN

TitleProfessor. Associate Dean for Research and Graduate Programs
InstitutionUniversity of Houston College of Pharmacy
DepartmentPharmacological & Pharmaceutical Sciences
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Nag S, Patel S, Mani S, Hussain T. Role of angiotensin type 2 receptor in improving lipid metabolism and preventing adiposity. Mol Cell Biochem. 2019 Nov; 461(1-2):195-204. PMID: 31414336.
      View in: PubMed
    2. Patel S, Dhande I, Gray EA, Ali Q, Hussain T. Prevention of lipopolysaccharide-induced CD11b+ immune cell infiltration in the kidney: role of AT2 receptors. Biosci Rep. 2019 May 31; 39(5). PMID: 31072913.
      View in: PubMed
    3. Patel S, Hussain T. Correction to: Dimerization of AT2 and Mas Receptors in Control of Blood Pressure. Curr Hypertens Rep. 2018 05 12; 20(5):47. PMID: 29754183.
      View in: PubMed
    4. Patel S, Hussain T. Dimerization of AT2 and Mas Receptors in Control of Blood Pressure. Curr Hypertens Rep. 2018 05 01; 20(5):41. PMID: 29717388.
      View in: PubMed
    5. Patel SN, Narayan P, Goldberg ID, Naaz F, Hussain T, Ali Q. Kidney Appreciates Stable Blood Pressure. Am J Hypertens. 2018 04 13; 31(5):532-533. PMID: 29272328.
      View in: PubMed
    6. Patel S, Hussain T. Role of AT2R (Angiotensin Type 2 Receptor) in Maintaining Sodium-Potassium Balance. Hypertension. 2018 04; 71(4):563-565. PMID: 29483226.
      View in: PubMed
    7. Boini KM, Hussain T, Li PL, Koka S. Trimethylamine-N-Oxide Instigates NLRP3 Inflammasome Activation and Endothelial Dysfunction. Cell Physiol Biochem. 2017; 44(1):152-162. PMID: 29130962.
      View in: PubMed
    8. Patel SN, Ali Q, Samuel P, Steckelings UM, Hussain T. Angiotensin II Type 2 Receptor and Receptor Mas Are Colocalized and Functionally Interdependent in Obese Zucker Rat Kidney. Hypertension. 2017 10; 70(4):831-838. PMID: 28827476.
      View in: PubMed
    9. Ali Q, Dhande I, Samuel P, Hussain T. Angiotensin type 2 receptor null mice express reduced levels of renal angiotensin II type 2 receptor/angiotensin (1-7)/Mas receptor and exhibit greater high-fat diet-induced kidney injury. J Renin Angiotensin Aldosterone Syst. 2016 Jul; 17(3). PMID: 27496559.
      View in: PubMed
    10. Patel SN, Ali Q, Hussain T. Angiotensin II Type 2-Receptor Agonist C21 Reduces Proteinuria and Oxidative Stress in Kidney of High-Salt-Fed Obese Zucker Rats. Hypertension. 2016 May; 67(5):906-15. PMID: 27021008.
      View in: PubMed
    11. Ali Q, Patel S, Hussain T. Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats. Am J Physiol Renal Physiol. 2015 Jun 15; 308(12):F1379-85. PMID: 25855512.
      View in: PubMed
    12. Nag S, Khan MA, Samuel P, Ali Q, Hussain T. Chronic angiotensin AT2R activation prevents high-fat diet-induced adiposity and obesity in female mice independent of estrogen. Metabolism. 2015 Jul; 64(7):814-25. PMID: 25869303.
      View in: PubMed
    13. Dhande I, Ma W, Hussain T. Angiotensin AT2 receptor stimulation is anti-inflammatory in lipopolysaccharide-activated THP-1 macrophages via increased interleukin-10 production. Hypertens Res. 2015 Jan; 38(1):21-9. PMID: 25209104.
      View in: PubMed
    14. Ali Q, Wu Y, Nag S, Hussain T. Estimation of angiotensin peptides in biological samples by LC/MS method. Anal Methods. 2014 Jan 21; 6(1):215-222. PMID: 24489613.
      View in: PubMed
    15. Ali Q, Wu Y, Hussain T. Chronic AT2 receptor activation increases renal ACE2 activity, attenuates AT1 receptor function and blood pressure in obese Zucker rats. Kidney Int. 2013 Nov; 84(5):931-9. PMID: 23823602.
      View in: PubMed
    16. Dhande I, Ali Q, Hussain T. Proximal tubule angiotensin AT2 receptors mediate an anti-inflammatory response via interleukin-10: role in renoprotection in obese rats. Hypertension. 2013 Jun; 61(6):1218-26. PMID: 23547236.
      View in: PubMed
    17. Samuel P, Khan MA, Nag S, Inagami T, Hussain T. Angiotensin AT(2) receptor contributes towards gender bias in weight gain. PLoS One. 2013; 8(1):e48425. PMID: 23341867.
      View in: PubMed
    18. Ali Q, Hussain T. AT2 receptor: Its role in obesity associated hypertension. Int J Clin Pharmacol Toxicol. 2012 Oct; 1(1):15-19. PMID: 27588222.
      View in: PubMed
    19. Asghar M, Tayebati SK, Lokhandwala MF, Hussain T. Potential dopamine-1 receptor stimulation in hypertension management. Curr Hypertens Rep. 2011 Aug; 13(4):294-302. PMID: 21633929.
      View in: PubMed
    20. Sabuhi R, Ali Q, Asghar M, Al-Zamily NR, Hussain T. Role of the angiotensin II AT2 receptor in inflammation and oxidative stress: opposing effects in lean and obese Zucker rats. Am J Physiol Renal Physiol. 2011 Mar; 300(3):F700-6. PMID: 21209001.
      View in: PubMed
    21. Sabuhi R, Asghar M, Hussain T. Inhibition of NAD(P)H oxidase potentiates AT2 receptor agonist-induced natriuresis in Sprague-Dawley rats. Am J Physiol Renal Physiol. 2010 Oct; 299(4):F815-20. PMID: 20668101.
      View in: PubMed
    22. Sourris KC, Morley AL, Koitka A, Samuel P, Coughlan MT, Penfold SA, Thomas MC, Bierhaus A, Nawroth PP, Yamamoto H, Allen TJ, Walther T, Hussain T, Cooper ME, Forbes JM. Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor. Diabetologia. 2010 Nov; 53(11):2442-51. PMID: 20631980.
      View in: PubMed
    23. Ali Q, Sabuhi R, Hussain T. High glucose up-regulates angiotensin II subtype 2 receptors via interferon regulatory factor-1 in proximal tubule epithelial cells. Mol Cell Biochem. 2010 Nov; 344(1-2):65-71. PMID: 20596758.
      View in: PubMed
    24. Siddiqui AH, Ali Q, Hussain T. Protective role of angiotensin II subtype 2 receptor in blood pressure increase in obese Zucker rats. Hypertension. 2009 Feb; 53(2):256-61. PMID: 19114640.
      View in: PubMed
    25. Siddiqui AH, Hussain T. Impaired angiotensin II AT(1) receptor function and enhanced Na, K-ATPase affinity for sodium in proximal tubule of streptozotocin-treated diabetic rats. Clin Exp Hypertens. 2007 Oct; 29(7):435-44. PMID: 17994353.
      View in: PubMed
    26. Shahid G, Hussain T. GRK2 negatively regulates glycogen synthesis in mouse liver FL83B cells. J Biol Chem. 2007 Jul 13; 282(28):20612-20. PMID: 17517892.
      View in: PubMed
    27. Siddiqui AH, Hussain T. Enhanced AT1 receptor-mediated vasocontractile response to ANG II in endothelium-denuded aorta of obese Zucker rats. Am J Physiol Heart Circ Physiol. 2007 Apr; 292(4):H1722-7. PMID: 17142345.
      View in: PubMed
    28. Hakam AC, Hussain T. Angiotensin II type 2 receptor agonist directly inhibits proximal tubule sodium pump activity in obese but not in lean Zucker rats. Hypertension. 2006 Jun; 47(6):1117-24. PMID: 16618840.
      View in: PubMed
    29. Hakam AC, Hussain T. Angiotensin II AT2 receptors inhibit proximal tubular Na+-K+-ATPase activity via a NO/cGMP-dependent pathway. Am J Physiol Renal Physiol. 2006 Jun; 290(6):F1430-6. PMID: 16380464.
      View in: PubMed
    30. Hakam AC, Siddiqui AH, Hussain T. Renal angiotensin II AT2 receptors promote natriuresis in streptozotocin-induced diabetic rats. Am J Physiol Renal Physiol. 2006 Feb; 290(2):F503-8. PMID: 16204414.
      View in: PubMed
    31. Banday AA, Siddiqui AH, Menezes MM, Hussain T. Insulin treatment enhances AT1 receptor function in OK cells. Am J Physiol Renal Physiol. 2005 Jun; 288(6):F1213-9. PMID: 15713908.
      View in: PubMed
    32. Hakam AC, Hussain T. Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats. Hypertension. 2005 Feb; 45(2):270-5. PMID: 15596573.
      View in: PubMed
    33. Banday AA, Hussain T, Lokhandwala MF. Renal dopamine D(1) receptor dysfunction is acquired and not inherited in obese Zucker rats. Am J Physiol Renal Physiol. 2004 Jul; 287(1):F109-16. PMID: 15068975.
      View in: PubMed
    34. Hussain T. Renal angiotensin II receptors, hyperinsulinemia, and obesity. Clin Exp Hypertens. 2003 Oct; 25(7):395-403. PMID: 14596364.
      View in: PubMed
    35. Asghar M, Hussain T, Lokhandwala MF. Overexpression of PKC-betaI and -delta contributes to higher PKC activity in the proximal tubules of old Fischer 344 rats. Am J Physiol Renal Physiol. 2003 Dec; 285(6):F1100-7. PMID: 12904329.
      View in: PubMed
    36. Banday AA, Asghar M, Hussain T, Lokhandwala MF. Dopamine-mediated inhibition of renal Na,K-ATPase is reduced by insulin. Hypertension. 2003 Jun; 41(6):1353-8. PMID: 12707290.
      View in: PubMed
    37. Hussain T, Lokhandwala MF. Renal dopamine receptors and hypertension. Exp Biol Med (Maywood). 2003 Feb; 228(2):134-42. PMID: 12563019.
      View in: PubMed
    38. Becker M, Umrani D, Lokhandwala MF, Hussain T. Increased renal angiotensin II AT1 receptor function in obese Zucker rat. Clin Exp Hypertens. 2003 Jan; 25(1):35-47. PMID: 12597523.
      View in: PubMed
    39. Umrani DN, Banday AA, Hussain T, Lokhandwala MF. Rosiglitazone treatment restores renal dopamine receptor function in obese Zucker rats. Hypertension. 2002 Dec; 40(6):880-5. PMID: 12468573.
      View in: PubMed
    40. Asghar M, Hussain T, Lokhandwala MF. Higher basal serine phosphorylation of D1A receptors in proximal tubules of old Fischer 344 rats. Am J Physiol Renal Physiol. 2002 Aug; 283(2):F350-5. PMID: 12110520.
      View in: PubMed
    41. Narkar VA, Hussain T, Lokhandwala MF. Activation of D2-like receptors causes recruitment of tyrosine-phosphorylated NKA alpha 1-subunits in kidney. Am J Physiol Renal Physiol. 2002 Dec; 283(6):F1290-5. PMID: 12388408.
      View in: PubMed
    42. Lucas-Teixeira VA, Hussain T, Serrão P, Soares-da-Silva P, Lokhandwala MF. Intestinal dopaminergic activity in obese and lean Zucker rats: response to high salt intake. Clin Exp Hypertens. 2002 Jul; 24(5):383-96. PMID: 12109778.
      View in: PubMed
    43. Narkar V, Hussain T, Lokhandwala M. Role of tyrosine kinase and p44/42 MAPK in D(2)-like receptor-mediated stimulation of Na(+), K(+)-ATPase in kidney. Am J Physiol Renal Physiol. 2002 Apr; 282(4):F697-702. PMID: 11880331.
      View in: PubMed
    44. Vieira-Coelho MA, Serrão P, Hussain T, Lokhandwala MF, Soares-da-Silva P. Salt intake and intestinal dopaminergic activity in adult and old Fischer 344 rats. Life Sci. 2001 Sep 14; 69(17):1957-68. PMID: 11589511.
      View in: PubMed
    45. Hogan YH, Florent G, Hussain T, Alkadhi KA. Cyclic AMP antagonizes adenosine-induced inhibition of ganglionic transmission. Brain Res. 1998 Mar 23; 787(2):242-7. PMID: 9518635.
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    46. Hasan A, Hussain T, Mustafa SJ, Srivastava PC. 2-substituted thioadenine nucleoside and nucleotide analogues: synthesis and receptor subtype binding affinities (1). Bioconjug Chem. 1994 Jul-Aug; 5(4):364-9. PMID: 7948104.
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    47. Shukla GS, Hussain T, Srivastava RS, Chandra SV. Glutathione peroxidase and catalase in liver, kidney, testis and brain regions of rats following cadmium exposure and subsequent withdrawal. Ind Health. 1989; 27(2):59-69. PMID: 2745162.
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    48. Shukla GS, Hussain T, Chandra SV. Protective effect of vitamin E on cadmium-induced alterations in lipofuscin and superoxide dismutase in rat brain regions. Pharmacol Toxicol. 1988 Oct; 63(4):305-6. PMID: 3194351.
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    49. Shukla GS, Hussain T, Chandra SV. Possible role of regional superoxide dismutase activity and lipid peroxide levels in cadmium neurotoxicity: in vivo and in vitro studies in growing rats. Life Sci. 1987 Nov 09; 41(19):2215-21. PMID: 3669920.
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    50. Hussain T, Ali MM, Chandra SV. The combined effect of Pb2+ and Mn2+ on monoamine uptake and Na+, K+-ATPase in striatal synaptosomes. J Appl Toxicol. 1987 Aug; 7(4):277-80. PMID: 3040846.
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    51. Hussain T, Shukla GS, Chandra SV. Effects of cadmium on superoxide dismutase and lipid peroxidation in liver and kidney of growing rats: in vivo and in vitro studies. Pharmacol Toxicol. 1987 May; 60(5):355-8. PMID: 3615346.
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    52. Saxena DK, Hussain T, Lal B, Chandra SV. Lead induced testicular dysfunction in weaned rats. Ind Health. 1986; 24(2):105-9. PMID: 3759508.
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    53. Chandra SV, Kalia K, Hussain T. Biogenic amines and some metals in brain of cadmium-exposed diabetic rats. J Appl Toxicol. 1985 Dec; 5(6):378-81. PMID: 4078219.
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    54. Bansal SK, Husain T, Murthy RC, Chandra SV. The effect of substrate and potassium on the inhibitory kinetics of MnCl2 on the enzyme K+-p-nitrophenyl phosphatase in rat brain. J Appl Toxicol. 1985 Feb; 5(1):35-8. PMID: 2985681.
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    55. Hussain T, Ali MM, Chandra SV. Effect of cadmium exposure on lipids, lipid peroxidation and metal distribution in rat brain regions. Ind Health. 1985; 23(3):199-205. PMID: 4066414.
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    56. Chandra SV, Murthy RC, Husain T, Bansal SK. Effect of interaction of heavy metals on (Na+ -K+) ATPase and the uptake of 3H-DA and 3H-NA in rat brain synaptosomes. Acta Pharmacol Toxicol (Copenh). 1984 Mar; 54(3):210-3. PMID: 6326468.
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