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JOYDIP DAS

TitleAssociate Professor
InstitutionUniversity of Houston College of Pharmacy
DepartmentPharmacological & Pharmaceutical Sciences
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wooden JI, Schuller K, Roman G, Das J, Leasure JL. Munc 13-1 heterozygosity does not alterVoluntary ethanol consumption or sensitivity in mice. Alcohol. 2019 Jun 29. PMID: 31265903.
      View in: PubMed
    2. Blanco FA, Czikora A, Kedei N, You Y, Mitchell GA, Pany S, Ghosh A, Blumberg PM, Das J. Munc13 Is a Molecular Target of Bryostatin 1. Biochemistry. 2019 Jul 09; 58(27):3016-3030. PMID: 31243993.
      View in: PubMed
    3. Das J. Identification of alcohol-binding site(s) in proteins using diazirine-based photoaffinity labeling and mass spectrometry. Chem Biol Drug Des. 2019 Jun; 93(6):1158-1165. PMID: 30346111.
      View in: PubMed
    4. Xu S, Pany S, Benny K, Tarique K, Al-Hatem O, Gajewski K, Leasure JL, Das J, Roman G. Ethanol Regulates Presynaptic Activity and Sedation through Presynaptic Unc13 Proteins in Drosophila. eNeuro. 2018 May-Jun; 5(3). PMID: 29911175.
      View in: PubMed
    5. Czikora A, Pany S, You Y, Saini AS, Lewin NE, Mitchell GA, Abramovitz A, Kedei N, Blumberg PM, Das J. Structural determinants of phorbol ester binding activity of the C1a and C1b domains of protein kinase C theta. Biochim Biophys Acta Biomembr. 2018 May; 1860(5):1046-1056. PMID: 29317197.
      View in: PubMed
    6. Das J, Kedei N, Kelsey JS, You Y, Pany S, Mitchell GA, Lewin NE, Blumberg PM. Critical Role of Trp-588 of Presynaptic Munc13-1 for Ligand Binding and Membrane Translocation. Biochemistry. 2018 02 06; 57(5):732-741. PMID: 29244485.
      View in: PubMed
    7. Das J, Fernandez J, Shah D, Williams L, Zagaar M. Case-based studies in teaching medicinal chemistry in PharmD curriculum: Perspectives of students, faculty, and pharmacists from academia. Curr Pharm Teach Learn. 2018 Jan - Feb; 10(1):85-89. PMID: 29248080.
      View in: PubMed
    8. Pany S, Ghosh A, You Y, Nguyen N, Das J. Resveratrol inhibits phorbol ester-induced membrane translocation of presynaptic Munc13-1. Biochim Biophys Acta Gen Subj. 2017 Nov; 1861(11 Pt A):2640-2651. PMID: 28713022.
      View in: PubMed
    9. Pany S, You Y, Das J. Curcumin Inhibits Protein Kinase Ca Activity by Binding to Its C1 Domain. Biochemistry. 2016 Nov 15; 55(45):6327-6336. PMID: 27776404.
      View in: PubMed
    10. Das J, Ramani R, Suraju MO. Polyphenol compounds and PKC signaling. Biochim Biophys Acta. 2016 10; 1860(10):2107-21. PMID: 27369735.
      View in: PubMed
    11. Das J. Drugs to Treat Alcohol Dependence-A Perspective. J Addict Depend. 2016; 2(2). PMID: 29756083.
      View in: PubMed
    12. Pany S, Majhi A, Das J. Selective Modulation of Protein Kinase C a over Protein Kinase C e by Curcumin and Its Derivatives in CHO-K1 Cells. Biochemistry. 2016 Apr 12; 55(14):2135-43. PMID: 26983836.
      View in: PubMed
    13. Das J. Novel N-pyrimidin-4-yl-3-amino-pyrrolo [3, 4-C] pyrazole derivatives as PKC kinase inhibitors: a patent evaluation of US2015099743 (A1). Expert Opin Ther Pat. 2016; 26(4):523-8. PMID: 26593678.
      View in: PubMed
    14. Pany S, Das J. Alcohol binding in the C1 (C1A+C1B) domain of protein kinase C epsilon. Biochim Biophys Acta. 2015 Nov; 1850(11):2368-76. PMID: 26210390.
      View in: PubMed
    15. Das J, Rahman GM. C1 domains: structure and ligand-binding properties. Chem Rev. 2014 Dec 24; 114(24):12108-31. PMID: 25375355.
      View in: PubMed
    16. Rahman GM, Das J. Modeling studies on the structural determinants for the DAG/phorbol ester binding to C1 domain. J Biomol Struct Dyn. 2015; 33(1):219-32. PMID: 24666138.
      View in: PubMed
    17. Das J, Xu S, Pany S, Guillory A, Shah V, Roman GW. The pre-synaptic Munc13-1 binds alcohol and modulates alcohol self-administration in Drosophila. J Neurochem. 2013 Sep; 126(6):715-26. PMID: 23692447.
      View in: PubMed
    18. Rahman GM, Shanker S, Lewin NE, Kedei N, Hill CS, Prasad BV, Blumberg PM, Das J. Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase C? (PKC?). Biochem J. 2013 Apr 01; 451(1):33-44. PMID: 23289588.
      View in: PubMed
    19. Pany S, Majhi A, Das J. PKC activation by resveratrol derivatives with unsaturated aliphatic chain. PLoS One. 2012; 7(12):e52888. PMID: 23285216.
      View in: PubMed
    20. Shanmugasundararaj S, Das J, Sandberg WS, Zhou X, Wang D, Messing RO, Bruzik KS, Stehle T, Miller KW. Structural and functional characterization of an anesthetic binding site in the second cysteine-rich domain of protein kinase Cd*. Biophys J. 2012 Dec 05; 103(11):2331-40. PMID: 23283232.
      View in: PubMed
    21. Das J. Protein Kinase C: The Drug Target One Must See. Med Chem (Los Angeles). 2012; 2(5). PMID: 29963330.
      View in: PubMed
    22. Das J, Pany S, Panchal S, Majhi A, Rahman GM. Binding of isoxazole and pyrazole derivatives of curcumin with the activator binding domain of novel protein kinase C. Bioorg Med Chem. 2011 Nov 01; 19(21):6196-202. PMID: 21975067.
      View in: PubMed
    23. Das J, Pany S, Majhi A. Chemical modifications of resveratrol for improved protein kinase C alpha activity. Bioorg Med Chem. 2011 Sep 15; 19(18):5321-33. PMID: 21880495.
      View in: PubMed
    24. Gupta SC, Kannappan R, Kim J, Rahman GM, Francis SK, Raveendran R, Nair MS, Das J, Aggarwal BB. Bharangin, a diterpenoid quinonemethide, abolishes constitutive and inducible nuclear factor-?B (NF-?B) activation by modifying p65 on cysteine 38 residue and reducing inhibitor of nuclear factor-?B a kinase activation, leading to suppression of NF-?B-regulated gene expression and sensitization of tumor cells to chemotherapeutic agents. Mol Pharmacol. 2011 Nov; 80(5):769-81. PMID: 21795584.
      View in: PubMed
    25. Howard RJ, Slesinger PA, Davies DL, Das J, Trudell JR, Harris RA. Alcohol-binding sites in distinct brain proteins: the quest for atomic level resolution. Alcohol Clin Exp Res. 2011 Sep; 35(9):1561-73. PMID: 21676006.
      View in: PubMed
    26. Das J. Aliphatic diazirines as photoaffinity probes for proteins: recent developments. Chem Rev. 2011 Aug 10; 111(8):4405-17. PMID: 21466226.
      View in: PubMed
    27. Majhi A, Rahman GM, Panchal S, Das J. Binding of curcumin and its long chain derivatives to the activator binding domain of novel protein kinase C. Bioorg Med Chem. 2010 Feb 15; 18(4):1591-8. PMID: 20100661.
      View in: PubMed
    28. Das J, Pany S, Rahman GM, Slater SJ. PKC epsilon has an alcohol-binding site in its second cysteine-rich regulatory domain. Biochem J. 2009 Jul 15; 421(3):405-13. PMID: 19432558.
      View in: PubMed
    29. Das J. Photoincorporation of azialcohol to the C1B domain of PKCdelta is buffer dependent. J Photochem Photobiol B. 2009 Jun 03; 95(3):185-8. PMID: 19359193.
      View in: PubMed
    30. Das J, Zhou X, Miller KW. Identification of an alcohol binding site in the first cysteine-rich domain of protein kinase Cdelta. Protein Sci. 2006 Sep; 15(9):2107-19. PMID: 16943444.
      View in: PubMed
    31. Das J, Addona GH, Sandberg WS, Husain SS, Stehle T, Miller KW. Identification of a general anesthetic binding site in the diacylglycerol-binding domain of protein kinase Cdelta. J Biol Chem. 2004 Sep 03; 279(36):37964-72. PMID: 15234976.
      View in: PubMed
    32. Das J, Crouch RK, Ma JX, Oprian DD, Kono M. Role of the 9-methyl group of retinal in cone visual pigments. Biochemistry. 2004 May 11; 43(18):5532-8. PMID: 15122919.
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    33. Ma J, Znoiko S, Othersen KL, Ryan JC, Das J, Isayama T, Kono M, Oprian DD, Corson DW, Cornwall MC, Cameron DA, Harosi FI, Makino CL, Crouch RK. A visual pigment expressed in both rod and cone photoreceptors. Neuron. 2001 Nov 08; 32(3):451-61. PMID: 11709156.
      View in: PubMed
    34. Ma JX, Kono M, Xu L, Das J, Ryan JC, Hazard ES, Oprian DD, Crouch RK. Salamander UV cone pigment: sequence, expression, and spectral properties. Vis Neurosci. 2001 May-Jun; 18(3):393-9. PMID: 11497415.
      View in: PubMed
    35. Das J, Crouch RK, Chong PL. Fluorescence properties of pyrylretinol. Photochem Photobiol. 2000 Sep; 72(3):415-20. PMID: 10989614.
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    36. Das J, Crouch RK, Govindjee R, Balashov S, Ebrey T. Studies on pyrylretinal analogues of bacteriorhodopsin. Photochem Photobiol. 1999 Dec; 70(6):949-56. PMID: 10628308.
      View in: PubMed
    37. Stecher H, Prezhdo O, Das J, Crouch RK, Palczewski K. Isomerization of all-trans-9- and 13-desmethylretinol by retinal pigment epithelial cells. Biochemistry. 1999 Oct 12; 38(41):13542-50. PMID: 10521261.
      View in: PubMed
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