WILLIAM H KLEIN

TitleProfessor
InstitutionMD Anderson
DepartmentSystems Biology
Address6767 Bertner St
Houston TX 77030-2603
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Budenz A, Sleight AG, Klein WMP. A qualitative study of online information-seeking preferences among cancer survivors. J Cancer Surviv. 2021 Sep 09. PMID: 34505207.
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    2. Gillman AS, Iles IA, Klein WMP, Biesecker BB, Lewis KL, Biesecker LG, Ferrer RA. The role of future-oriented affect in engagement with genomic testing results. J Behav Med. 2021 Sep 04. PMID: 34480685.
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    3. Iles IA, Gillman AS, Klein WMP, Ferrer RA, Kaufman A. Associations between absolute and relative electronic cigarette harm perceptions and information-seeking behaviours among US adult current, former and never smokers. Drug Alcohol Rev. 2021 Aug 03. PMID: 34342384.
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    4. Iles IA, Gillman AS, Ferrer RA, Klein WMP. Self-affirmation inductions to reduce defensive processing of threatening health risk information. Psychol Health. 2021 Jul 29; 1-22. PMID: 34323138.
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    5. Klein WMP, O'Connell ME, Bloch MH, Czajkowski SM, Green PA, Han PKJ, Moser RP, Nebeling LC, Vanderpool RC. Behavioral Research in Cancer Prevention and Control: Emerging Challenges and Opportunities. J Natl Cancer Inst. 2021 Jul 07. PMID: 34240206.
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    6. Chavez-Yenter D, Zhao J, Ratcliff CL, Kehoe K, Blumling A, Peterson E, Klein WMP, Sylvia Chou WY, Kaphingst KA. Theory utilization in current communication of cancer genetic testing research: Identified gaps and opportunities. Soc Sci Med. 2021 08; 282:114144. PMID: 34153821.
      Citations:    Fields:    Translation:Humans
    7. Peterson EB, Taber JM, Klein WMP. Information Avoidance, Self-affirmation, and Intentions to Receive Genomic Sequencing Results Among Members of an African Descent Cohort. Ann Behav Med. 2021 Jun 05. PMID: 34089040.
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    8. Huelsnitz CO, Turbitt E, Taber JM, Lewis KL, Biesecker LG, Biesecker BB, Klein WMP. Dyadic concordance and associations of beliefs with intentions to learn carrier results from genomic sequencing. J Behav Med. 2021 May 13. PMID: 33987754.
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    9. Packard A, Klein WH, Costantini F. Ret signaling in ureteric bud epithelial cells controls cell movements, cell clustering and bud formation. Development. 2021 05 01; 148(9). PMID: 33914865.
      Citations:    Fields:    Translation:AnimalsCells
    10. Sorgen LJ, Ferrer RA, Klein WMP, Kaufman AR. Smoking self-concept moderates the effects of self-affirmation on smoking-related beliefs and behavioral intentions. Psychol Health. 2021 Apr 19; 1-21. PMID: 33870815.
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    11. Klein WMP, Boutté AK, Brake H, Beal M, Lyon-Daniel K, Eisenhauer E, Grasso M, Hubbell B, Jenni KE, Lauer CJ, Lupia AW, Prue CE, Rausch P, Shapiro CD, Smith MD, Riley WT. Leveraging risk communication science across US federal agencies. Nat Hum Behav. 2021 04; 5(4):411-413. PMID: 33737732.
      Citations:    Fields:    Translation:HumansPHPublic Health
    12. Roberts MC, Seaman EL, Klein WMP, Ferrer RA, Han PKJ, Katki HA, Land SR, Liotta RA, Nations JA, Peterson PG. Patient Perspectives on the Risk-Based NLST Outcomes Tool for Lung Cancer Screening. J Cancer Educ. 2021 Mar 09. PMID: 33686613.
      Citations:    Fields:    
    13. Suls J, Ferrer RA, Klein WMP. Temporal and social comparative self-assessments of physical health in young, middle-aged, and young-old adults in the MIDUS study. J Behav Med. 2021 06; 44(3):333-344. PMID: 33682049.
      Citations:    Fields:    Translation:Humans
    14. Seaman EL, Robinson CD, Crane D, Taber JM, Ferrer RA, Harris PR, Klein WMP. Association of Spontaneous and Induced Self-Affirmation With Smoking Cessation in Users of a Mobile App: Randomized Controlled Trial. J Med Internet Res. 2021 03 05; 23(3):e18433. PMID: 33666561.
      Citations:    Fields:    Translation:Humans
    15. Kelly L, Seifi M, Ma R, Mitchell SJ, Rudolph U, Viola KL, Klein WL, Lambert JJ, Swinny JD. Identification of intraneuronal amyloid beta oligomers in locus coeruleus neurons of Alzheimer's patients and their potential impact on inhibitory neurotransmitter receptors and neuronal excitability. Neuropathol Appl Neurobiol. 2021 06; 47(4):488-505. PMID: 33119191.
      Citations: 4     Fields:    
    16. Turbitt E, Klein WMP, Rogers K, D'Amanda CS, Biesecker BB. Parental decision making about clinical trial enrollment: A survey of parents of children with Fragile X syndrome. Health Psychol. 2020 Dec; 39(12):1070-1077. PMID: 33252931.
      Citations:    Fields:    Translation:Humans
    17. Bitencourt ALB, Campos RM, Cline EN, Klein WL, Sebollela A. Antibody Fragments as Tools for Elucidating Structure-Toxicity Relationships and for Diagnostic/Therapeutic Targeting of Neurotoxic Amyloid Oligomers. Int J Mol Sci. 2020 Nov 24; 21(23). PMID: 33255488.
      Citations: 1     Fields:    Translation:HumansAnimals
    18. Dutcher JM, Eisenberger NI, Woo H, Klein WMP, Harris PR, Levine JM, Creswell JD. Neural mechanisms of self-affirmation's stress buffering effects. Soc Cogn Affect Neurosci. 2020 11 10; 15(10):1086-1096. PMID: 32248237.
      Citations: 3     Fields:    Translation:Humans
    19. Kaufman AR, Twesten JE, Suls J, McCaul KD, Ostroff JS, Ferrer RA, Brewer NT, Cameron LD, Halpern-Felsher B, Hay JL, Park ER, Peters E, Strong DR, Waters EA, Weinstein ND, Windschitl PD, Klein WMP. Measuring Cigarette Smoking Risk Perceptions. Nicotine Tob Res. 2020 10 29; 22(11):1937-1945. PMID: 31883013.
      Citations: 5     Fields:    Translation:Humans
    20. Davis KW, Roter DL, Schmidlen T, Scheinfeldt LB, Klein WMP. Testing a best practices risk result format to communicate genetic risks. Patient Educ Couns. 2021 05; 104(5):936-943. PMID: 33131927.
      Citations: 2     Fields:    Translation:Humans
    21. Rozema NB, Procissi D, Bertolino N, Viola KL, Nandwana V, Abdul N, Pribus S, Dravid V, Klein WL, Disterhoft JF, Weiss C. Aß oligomer induced cognitive impairment and evaluation of ACU193-MNS-based MRI in rabbit. Alzheimers Dement (N Y). 2020; 6(1):e12087. PMID: 33072847.
      Citations:    
    22. Schwartz MLB, Klein WMP, Erby LAH, Smith CH, Roter DL. The impact of the number of tests presented and a provider recommendation on decisions about genetic testing for cancer risk. Patient Educ Couns. 2021 02; 104(2):265-275. PMID: 32994107.
      Citations:    Fields:    Translation:Humans
    23. Ferrer RA, Taber JM, Sheeran P, Bryan AD, Cameron LD, Peters E, Lerner JS, Grenen E, Klein WMP. The role of incidental affective states in appetitive risk behavior: A meta-analysis. Health Psychol. 2020 Dec; 39(12):1109-1124. PMID: 32940529.
      Citations: 2     Fields:    Translation:Humans
    24. Ferrer RA, Cerully JL, Harris PR, Klein WMP. Greater benefit of self-affirmation for prevention-focused individuals prior to threatening health messages. Psychol Health. 2021 06; 36(6):719-738. PMID: 32781845.
      Citations:    Fields:    Translation:Humans
    25. Klein WMP, Ferrer RA, Kaufman AR. How (or Do) People "Think" About Cancer Risk, and Why That Matters. JAMA Oncol. 2020 07 01; 6(7):983-984. PMID: 32437492.
      Citations: 5     Fields:    Translation:Humans
    26. Reid AE, Ferrer RA, Kadirvel S, Biesecker BB, Lewis KL, Biesecker LG, Klein WMP. Roles of attitudes and injunctive norms in decisional conflict and disclosure following receipt of genome sequencing results. Soc Sci Med. 2020 10; 262:113147. PMID: 32624263.
      Citations:    Fields:    Translation:Humans
    27. Magnan RE, Schmiege SJ, Klein WMP, Bryan AD. Effects of peer versus expert exercise standards on exercise cognitions and behaviour. Psychol Health. 2020 11; 35(11):1407-1420. PMID: 32212932.
      Citations:    Fields:    Translation:Humans
    28. Welikovitch LA, Do Carmo S, Maglóczky Z, Malcolm JC, Loke J, Klein WL, Freund T, Cuello AC. Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain. Proc Natl Acad Sci U S A. 2020 03 24; 117(12):6844-6854. PMID: 32144141.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    29. Simonovic N, Taber JM, Klein WMP, Ferrer RA. Evidence that perceptions of and tolerance for medical ambiguity are distinct constructs: An analysis of nationally representative US data. Health Expect. 2020 06; 23(3):603-613. PMID: 32097530.
      Citations: 2     Fields:    Translation:Humans
    30. Klein WMP, Rothman AJ, Suls J. Bridging Behavioral Science with Cancer Prevention and Control: Contributions of an NCI Working Group (2009-2019). Cancer Prev Res (Phila). 2020 04; 13(4):337-342. PMID: 31969345.
      Citations:    Fields:    Translation:Humans
    31. Klein WMP, Jacobsen PB, Helzlsouer KJ. Alcohol and Cancer Risk: Clinical and Research Implications. JAMA. 2020 Jan 07; 323(1):23-24. PMID: 31834355.
      Citations: 4     Fields:    Translation:Humans
    32. Hagerman CJ, Ferrer RA, Klein WMP, Persky S. Association of parental guilt with harmful versus healthful eating and feeding from a virtual reality buffet. Health Psychol. 2020 Mar; 39(3):199-208. PMID: 31829660.
      Citations: 1     Fields:    Translation:Humans
    33. Wand H, Sturm AC, Erby L, Kindt I, Klein WMP. Genetic testing preferences and intentions in patients with clinically diagnosed familial hypercholesterolemia. J Genet Couns. 2020 12; 29(6):919-927. PMID: 31769116.
      Citations:    Fields:    Translation:Humans
    34. Ding Y, Zhao J, Zhang X, Wang S, Viola KL, Chow FE, Zhang Y, Lippa C, Klein WL, Gong Y. Amyloid Beta Oligomers Target to Extracellular and Intracellular Neuronal Synaptic Proteins in Alzheimer's Disease. Front Neurol. 2019; 10:1140. PMID: 31736856.
      Citations: 12     
    35. Zullo JM, Drake D, Aron L, O'Hern P, Dhamne SC, Davidsohn N, Mao CA, Klein WH, Rotenberg A, Bennett DA, Church GM, Colaiácovo MP, Yankner BA. Regulation of lifespan by neural excitation and REST. Nature. 2019 10; 574(7778):359-364. PMID: 31619788.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    36. Persky S, Ferrer RA, Klein WMP, Goldring MR, Cohen RW, Kistler WD, Yaremych HE, Bouhlal S. Effects of Fruit and Vegetable Feeding Messages on Mothers and Fathers: Interactions Between Emotional State and Health Message Framing. Ann Behav Med. 2019 08 16; 53(9):789-800. PMID: 30395145.
      Citations: 9     Fields:    Translation:HumansAnimals
    37. Wiseman KP, Klein WMP. Evaluating Correlates of Awareness of the Association between Drinking Too Much Alcohol and Cancer Risk in the United States. Cancer Epidemiol Biomarkers Prev. 2019 07; 28(7):1195-1201. PMID: 31043419.
      Citations: 5     Fields:    Translation:Humans
    38. Kiyama T, Long Y, Chen CK, Whitaker CM, Shay A, Wu H, Badea TC, Mohsenin A, Parker-Thornburg J, Klein WH, Mills SL, Massey SC, Mao CA. Essential Roles of Tbr1 in the Formation and Maintenance of the Orientation-Selective J-RGCs and a Group of OFF-Sustained RGCs in Mouse. Cell Rep. 2019 04 16; 27(3):900-915.e5. PMID: 30995485.
      Citations: 2     Fields:    Translation:AnimalsCells
    39. Rice EL, Klein WMP. Interactions among perceived norms and attitudes about health-related behaviors in U.S. adolescents. Health Psychol. 2019 Mar; 38(3):268-275. PMID: 30762406.
      Citations: 7     Fields:    Translation:Humans
    40. Czajkowski SM, Riley WT, Stoney CM, Klein WMP, Croyle RT. Key milestones during 40 years of behavioral medicine at the National Institutes of Health. J Behav Med. 2019 02; 42(1):34-51. PMID: 30825087.
      Citations:    Fields:    Translation:HumansPHPublic Health
    41. Turbitt E, Roberts MC, Taber JM, Waters EA, McNeel TS, Biesecker BB, Klein WMP. Genetic counseling, genetic testing, and risk perceptions for breast and colorectal cancer: Results from the 2015 National Health Interview Survey. Prev Med. 2019 06; 123:12-19. PMID: 30817954.
      Citations: 2     Fields:    Translation:Humans
    42. Klein WMP, McBride CM, Allen CG, Arredondo EM, Bloss CS, Kaphingst KA, Sturm AC, Wang C. Optimal Integration of Behavioral Medicine into Clinical Genetics and Genomics. Am J Hum Genet. 2019 02 07; 104(2):193-196. PMID: 30735659.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    43. Cline EN, Das A, Bicca MA, Mohammad SN, Schachner LF, Kamel JM, DiNunno N, Weng A, Paschall JD, Bu RL, Khan FM, Rollins MG, Ives AN, Shekhawat G, Nunes-Tavares N, de Mello FG, Compton PD, Kelleher NL, Klein WL. A novel crosslinking protocol stabilizes amyloid ß oligomers capable of inducing Alzheimer's-associated pathologies. J Neurochem. 2019 03; 148(6):822-836. PMID: 30565253.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    44. Xie Z, Shapiro LP, Cahill ME, Russell TA, Lacor PN, Klein WL, Penzes P. Kalirin-7 prevents dendritic spine dysgenesis induced by amyloid beta-derived oligomers. Eur J Neurosci. 2019 05; 49(9):1091-1101. PMID: 30565792.
      Citations: 6     Fields:    Translation:AnimalsCells
    45. Turbitt E, Roberts MC, Hollister BM, Lewis KL, Biesecker LG, Klein WMP. Ethnic identity and engagement with genome sequencing research. Genet Med. 2019 08; 21(8):1735-1743. PMID: 30568309.
      Citations: 1     Fields:    Translation:Humans
    46. Chou WS, Oh A, Klein WMP. Addressing Health-Related Misinformation on Social Media. JAMA. 2018 Dec 18; 320(23):2417-2418. PMID: 30428002.
      Citations: 78     Fields:    
    47. Ellis EM, Ferrer RA, Klein WMP. Factors beyond Lack of Knowledge That Predict "I Don't Know" Responses to Surveys That Assess HPV Knowledge. J Health Commun. 2018; 23(10-11):967-976. PMID: 30526402.
      Citations: 5     Fields:    
    48. Silver MI, Klein W, Samimi G, Minasian L, Loud J, Roberts MC. Concordance with BRCA1/2 testing guidelines among women in The Health of Women (HOW) Study®. Breast Cancer Res Treat. 2019 Feb; 173(3):719-726. PMID: 30413980.
      Citations: 3     Fields:    Translation:Humans
    49. Lewis KL, Heidlebaugh AR, Epps S, Han PKJ, Fishler KP, Klein WMP, Miller IM, Ng D, Hepler C, Biesecker BB, Biesecker LG. Knowledge, motivations, expectations, and traits of an African, African-American, and Afro-Caribbean sequencing cohort and comparisons to the original ClinSeq® cohort. Genet Med. 2019 06; 21(6):1355-1362. PMID: 30382154.
      Citations: 4     Fields:    Translation:Humans
    50. Ellis EM, Klein WMP, Orehek E, Ferrer RA. Effects of Emotion on Medical Decisions Involving Tradeoffs. Med Decis Making. 2018 11; 38(8):1027-1039. PMID: 30343624.
      Citations: 5     Fields:    Translation:Humans
    51. Kiyama T, Chen CK, Wang SW, Pan P, Ju Z, Wang J, Takada S, Klein WH, Mao CA. Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis. Mol Neurodegener. 2018 10 17; 13(1):56. PMID: 30333037.
      Citations: 16     Fields:    Translation:AnimalsCells
    52. Shapira R, Turbitt E, Erby LH, Biesecker BB, Klein WMP, Hooker GW. Adaptation of couples living with a high risk of breast/ovarian cancer and the association with risk-reducing surgery. Fam Cancer. 2018 10; 17(4):485-493. PMID: 29209897.
      Citations:    Fields:    Translation:Humans
    53. Dillard AJ, Ferrer RA, Bulthuis KRK, Klein WMP. Positive excessive drinker prototypes predict greater drinking and alcohol problems. Br J Health Psychol. 2018 11; 23(4):1000-1020. PMID: 30084206.
      Citations:    Fields:    Translation:Humans
    54. Roberts MC, Taber JM, Klein WM. Engagement with Genetic Information and Uptake of Genetic Testing: the Role of Trust and Personal Cancer History. J Cancer Educ. 2018 08; 33(4):893-900. PMID: 28105554.
      Citations: 6     Fields:    Translation:Humans
    55. Persky S, Kistler WD, Klein WMP, Ferrer RA. Internet Versus Virtual Reality Settings for Genomics Information Provision. Cyberpsychol Behav Soc Netw. 2019 Jan; 22(1):7-14. PMID: 29932735.
      Citations: 1     Fields:    Translation:Humans
    56. Hellwig LD, Biesecker BB, Lewis KL, Biesecker LG, James CA, Klein WMP. Ability of Patients to Distinguish Among Cardiac Genomic Variant Subclassifications. Circ Genom Precis Med. 2018 06; 11(6):e001975. PMID: 29848613.
      Citations: 4     Fields:    Translation:Humans
    57. Mendes ND, Fernandes A, Almeida GM, Santos LE, Selles MC, Lyra E Silva NM, Machado CM, Horta-Júnior JAC, Louzada PR, De Felice FG, Alves-Leon S, Marcondes J, Assirati JA, Matias CM, Klein WL, Garcia-Cairasco N, Ferreira ST, Neder L, Sebollela A. Free-floating adult human brain-derived slice cultures as a model to study the neuronal impact of Alzheimer's disease-associated Aß oligomers. J Neurosci Methods. 2018 09 01; 307:203-209. PMID: 29859877.
      Citations: 6     Fields:    Translation:HumansCells
    58. Reid AE, Taber JM, Ferrer RA, Biesecker BB, Lewis KL, Biesecker LG, Klein WMP. Associations of perceived norms with intentions to learn genomic sequencing results: Roles for attitudes and ambivalence. Health Psychol. 2018 06; 37(6):553-561. PMID: 29745680.
      Citations: 2     Fields:    Translation:Humans
    59. Klein WMP, Ferrer RA. On Being More Amenable to Threatening Risk Messages Concerning Close Others (vis-à-vis the Self). Pers Soc Psychol Bull. 2018 10; 44(10):1411-1423. PMID: 29716420.
      Citations: 1     Fields:    Translation:Humans
    60. Biesecker BB, Woolford SW, Klein WMP, Brothers KB, Umstead KL, Lewis KL, Biesecker LG, Han PKJ. Correction to: PUGS: A novel scale to assess perceptions of uncertainties in genome sequencing. Clin Genet. 2018 05; 93(5):1119. PMID: 29655271.
      Citations:    Fields:    
    61. Batista AF, Forny-Germano L, Clarke JR, Lyra E Silva NM, Brito-Moreira J, Boehnke SE, Winterborn A, Coe BC, Lablans A, Vital JF, Marques SA, Martinez AM, Gralle M, Holscher C, Klein WL, Houzel JC, Ferreira ST, Munoz DP, De Felice FG. The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease. J Pathol. 2018 05; 245(1):85-100. PMID: 29435980.
      Citations: 51     Fields:    Translation:AnimalsCells
    62. Roberts MC, Ferrer RA, Rendle KA, Kobrin SC, Taplin SH, Hesse BW, Klein WMP. Lay Beliefs About the Accuracy and Value of Cancer Screening. Am J Prev Med. 2018 May; 54(5):699-703. PMID: 29551327.
      Citations: 2     Fields:    Translation:Humans
    63. Kaufman AR, Dwyer LA, Land SR, Klein WMP, Park ER. Smoking-related health beliefs and smoking behavior in the National Lung Screening Trial. Addict Behav. 2018 09; 84:27-32. PMID: 29605757.
      Citations: 1     Fields:    Translation:Humans
    64. Lawal TA, Lewis KL, Johnston JJ, Heidlebaugh AR, Ng D, Gaston-Johansson FG, Klein WMP, Biesecker BB, Biesecker LG. Disclosure of cardiac variants of uncertain significance results in an exome cohort. Clin Genet. 2018 05; 93(5):1022-1029. PMID: 29383714.
      Citations: 4     Fields:    Translation:Humans
    65. Ferrer RA, Klein WMP, Avishai A, Jones K, Villegas M, Sheeran P. When does risk perception predict protection motivation for health threats? A person-by-situation analysis. PLoS One. 2018; 13(3):e0191994. PMID: 29494705.
      Citations: 14     Fields:    Translation:Humans
    66. Turbitt E, Roberts MC, Ferrer RA, Taber JM, Lewis KL, Biesecker LG, Biesecker BB, Klein WM. Intentions to share exome sequencing results with family members: exploring spousal beliefs and attitudes. Eur J Hum Genet. 2018 05; 26(5):735-739. PMID: 29476166.
      Citations:    Fields:    Translation:Humans
    67. Ellis EM, Ferrer RA, Taber JM, Klein WMP. Relationship of "don't know" responses to cancer knowledge and belief questions with colorectal cancer screening behavior. Health Psychol. 2018 04; 37(4):394-398. PMID: 29389156.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    68. Cline EN, Bicca MA, Viola KL, Klein WL. The Amyloid-ß Oligomer Hypothesis: Beginning of the Third Decade. J Alzheimers Dis. 2018; 64(s1):S567-S610. PMID: 29843241.
      Citations: 134     Fields:    Translation:HumansAnimals
    69. Ferrer RA, Lipkus IM, Cerully JL, McBride CM, Shepperd JA, Klein WMP. Developing a scale to assess health regulatory focus. Soc Sci Med. 2017 12; 195:50-60. PMID: 29144984.
      Citations: 3     Fields:    Translation:Humans
    70. Taber JM, Klein WMP, Persky S, Ferrer RA, Kaufman AR, Thai CL, Harris PR. Interest in and reactions to genetic risk information: The role of implicit theories and self-affirmation. Soc Sci Med. 2017 10; 190:101-110. PMID: 28858695.
      Citations:    Fields:    Translation:Humans
    71. Pitt J, Wilcox KC, Tortelli V, Diniz LP, Oliveira MS, Dobbins C, Yu XW, Nandamuri S, Gomes FCA, DiNunno N, Viola KL, De Felice FG, Ferreira ST, Klein WL. Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aß oligomers. Mol Biol Cell. 2017 Oct 01; 28(20):2623-2636. PMID: 28963439.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    72. Sebollela A, Cline EN, Popova I, Luo K, Sun X, Ahn J, Barcelos MA, Bezerra VN, Lyra E Silva NM, Patel J, Pinheiro NR, Qin LA, Kamel JM, Weng A, DiNunno N, Bebenek AM, Velasco PT, Viola KL, Lacor PN, Ferreira ST, Klein WL. A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-ß oligomers. J Neurochem. 2017 Sep; 142(6):934-947. PMID: 28670737.
      Citations: 7     Fields:    
    73. Taber JM, Klein WMP, Lewis KL, Johnston JJ, Biesecker LG, Biesecker BB. Reactions to clinical reinterpretation of a gene variant by participants in a sequencing study. Genet Med. 2018 03; 20(3):337-345. PMID: 28771245.
      Citations: 4     Fields:    Translation:Humans
    74. Haure-Mirande JV, Audrain M, Fanutza T, Kim SH, Klein WL, Glabe C, Readhead B, Dudley JT, Blitzer RD, Wang M, Zhang B, Schadt EE, Gandy S, Ehrlich ME. Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology. Acta Neuropathol. 2017 11; 134(5):769-788. PMID: 28612290.
      Citations: 28     Fields:    Translation:AnimalsCells
    75. Scheideler JK, Taber JM, Ferrer RA, Grenen EG, Klein WMP. Heart disease versus cancer: understanding perceptions of population prevalence and personal risk. J Behav Med. 2017 Oct; 40(5):839-845. PMID: 28577198.
      Citations: 1     Fields:    Translation:Humans
    76. Kiviniemi MT, Ellis EM, Hall MG, Moss JL, Lillie SE, Brewer NT, Klein WMP. Mediation, moderation, and context: Understanding complex relations among cognition, affect, and health behaviour. Psychol Health. 2018 01; 33(1):98-116. PMID: 28488897.
      Citations: 6     Fields:    Translation:Humans
    77. Cameron LD, Biesecker BB, Peters E, Taber JM, Klein WMP. Self-Regulation Principles Underlying Risk Perception and Decision Making within the Context of Genomic Testing. Soc Personal Psychol Compass. 2017 May; 11(5). PMID: 29225669.
      Citations: 5     
    78. Taber JM, Klein WM, Suls JM, Ferrer RA. Lay Awareness of the Relationship between Age and Cancer Risk. Ann Behav Med. 2017 Apr; 51(2):214-225. PMID: 27752991.
      Citations: 5     Fields:    Translation:Humans
    79. Fowler SL, Klein WMP, Ball L, McGuire J, Colditz GA, Waters EA. Using an Internet-Based Breast Cancer Risk Assessment Tool to Improve Social-Cognitive Precursors of Physical Activity. Med Decis Making. 2017 08; 37(6):657-669. PMID: 28363033.
      Citations: 5     Fields:    Translation:Humans
    80. Zhang Q, Zagozewski J, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Brown NL, Wigle JT, Schuurmans C, Eisenstat DD. Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina. Development. 2017 05 01; 144(9):1698-1711. PMID: 28356311.
      Citations: 10     Fields:    Translation:AnimalsCells
    81. DiChiara T, DiNunno N, Clark J, Bu RL, Cline EN, Rollins MG, Gong Y, Brody DL, Sligar SG, Velasco PT, Viola KL, Klein WL. Alzheimer's Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station. Yale J Biol Med. 2017 03; 90(1):45-61. PMID: 28356893.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    82. Seixas da Silva GS, Melo HM, Lourenco MV, Lyra E Silva NM, de Carvalho MB, Alves-Leon SV, de Souza JM, Klein WL, da-Silva WS, Ferreira ST, De Felice FG. Amyloid-ß oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons. J Biol Chem. 2017 05 05; 292(18):7395-7406. PMID: 28302722.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    83. Yin J, Zhao F, Chojnacki JE, Fulp J, Klein WL, Zhang S, Zhu X. NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer's Disease. Mol Neurobiol. 2018 03; 55(3):1977-1987. PMID: 28255908.
      Citations: 34     Fields:    Translation:Animals
    84. Klein WM, Grenen EG, O'Connell M, Blanch-Hartigan D, Chou WS, Hall KL, Taber JM, Vogel AL. Integrating knowledge across domains to advance the science of health behavior: overcoming challenges and facilitating success. Transl Behav Med. 2017 03; 7(1):98-105. PMID: 27520313.
      Citations: 4     Fields:    Translation:Humans
    85. Ferrer RA, Klein WM, Graff KA. Self-affirmation increases defensiveness toward health risk information among those experiencing negative emotions: Results from two national samples. Health Psychol. 2017 Apr; 36(4):380-391. PMID: 28206787.
      Citations: 4     Fields:    Translation:Humans
    86. Biesecker BB, Woolford SW, Klein WMP, Brothers KB, Umstead KL, Lewis KL, Biesecker LG, Han PKJ. PUGS: A novel scale to assess perceptions of uncertainties in genome sequencing. Clin Genet. 2017 Aug; 92(2):172-179. PMID: 27925165.
      Citations: 9     Fields:    Translation:Humans
    87. Solomon I, Harrington E, Hooker G, Erby L, Axilbund J, Hampel H, Semotiuk K, Blanco A, Klein WMP, Giardiello F, Leonard L. Lynch Syndrome Limbo: Patient Understanding of Variants of Uncertain Significance. J Genet Couns. 2017 Aug; 26(4):866-877. PMID: 28127677.
      Citations: 16     Fields:    Translation:Humans
    88. Ferrer RA, Klein WM, Persoskie A, Avishai-Yitshak A, Sheeran P. The Tripartite Model of Risk Perception (TRIRISK): Distinguishing Deliberative, Affective, and Experiential Components of Perceived Risk. Ann Behav Med. 2016 10; 50(5):653-663. PMID: 26961206.
      Citations: 47     Fields:    Translation:Humans
    89. Kessels LT, Harris PR, Ruiter RA, Klein WM. Attentional effects of self-affirmation in response to graphic antismoking images. Health Psychol. 2016 Aug; 35(8):891-7. PMID: 27505212.
      Citations: 2     Fields:    Translation:Humans
    90. Savioz A, Giannakopoulos P, Herrmann FR, Klein WL, Kövari E, Bouras C, Giacobini E. A Study of Aß Oligomers in the Temporal Cortex and Cerebellum of Patients with Neuropathologically Confirmed Alzheimer's Disease Compared to Aged Controls. Neurodegener Dis. 2016; 16(5-6):398-406. PMID: 27400224.
      Citations: 7     Fields:    Translation:HumansCells
    91. Taber JM, Klein WM, Ferrer RA, Augustson E, Patrick H. A Pilot Test of Self-Affirmations to Promote Smoking Cessation in a National Smoking Cessation Text Messaging Program. JMIR Mhealth Uhealth. 2016 Jun 08; 4(2):e71. PMID: 27278108.
      Citations: 3     Fields:    
    92. Persky S, Ferrer RA, Klein WM. Genomic Information may Inhibit Weight-Related Behavior Change Inclinations Among Individuals in a Fear State. Ann Behav Med. 2016 06; 50(3):452-9. PMID: 26850762.
      Citations: 5     Fields:    Translation:Humans
    93. Knight EM, Kim SH, Kottwitz JC, Hatami A, Albay R, Suzuki A, Lublin A, Alberini CM, Klein WL, Szabo P, Relkin NR, Ehrlich M, Glabe CG, Gandy S, Steele JW. Effective anti-Alzheimer Aß therapy involves depletion of specific Aß oligomer subtypes. Neurol Neuroimmunol Neuroinflamm. 2016 Jun; 3(3):e237. PMID: 27218118.
      Citations: 19     Fields:    
    94. Emanuel AS, Howell JL, Taber JM, Ferrer RA, Klein WM, Harris PR. Spontaneous self-affirmation is associated with psychological well-being: Evidence from a US national adult survey sample. J Health Psychol. 2018 01; 23(1):95-102. PMID: 27160152.
      Citations: 4     Fields:    Translation:Humans
    95. Persky S, Ferrer RA, Klein WM. Nonverbal and paraverbal behavior in (simulated) medical visits related to genomics and weight: a role for emotion and race. J Behav Med. 2016 Oct; 39(5):804-14. PMID: 27146511.
      Citations: 6     Fields:    Translation:Humans
    96. Lauritzen I, Pardossi-Piquard R, Bourgeois A, Pagnotta S, Biferi MG, Barkats M, Lacor P, Klein W, Bauer C, Checler F. Intraneuronal aggregation of the ß-CTF fragment of APP (C99) induces Aß-independent lysosomal-autophagic pathology. Acta Neuropathol. 2016 08; 132(2):257-276. PMID: 27138984.
      Citations: 59     Fields:    Translation:AnimalsCells
    97. Taber JM, Klein WM, Ferrer RA, Kent EE, Harris PR. Optimism and Spontaneous Self-affirmation are Associated with Lower Likelihood of Cognitive Impairment and Greater Positive Affect among Cancer Survivors. Ann Behav Med. 2016 Apr; 50(2):198-209. PMID: 26497697.
      Citations: 5     Fields:    Translation:Humans
    98. Umeda T, Ono K, Sakai A, Yamashita M, Mizuguchi M, Klein WL, Yamada M, Mori H, Tomiyama T. Rifampicin is a candidate preventive medicine against amyloid-ß and tau oligomers. Brain. 2016 05; 139(Pt 5):1568-86. PMID: 27020329.
      Citations: 31     Fields:    Translation:AnimalsCells
    99. Mao CA, Agca C, Mocko-Strand JA, Wang J, Ullrich-Lüter E, Pan P, Wang SW, Arnone MI, Frishman LJ, Klein WH. Substituting mouse transcription factor Pou4f2 with a sea urchin orthologue restores retinal ganglion cell development. Proc Biol Sci. 2016 Mar 16; 283(1826):20152978. PMID: 26962139.
      Citations: 2     Fields:    Translation:AnimalsCells
    100. Knight EM, Ruiz HH, Kim SH, Harte JC, Hsieh W, Glabe C, Klein WL, Attie AD, Buettner C, Ehrlich ME, Gandy S. Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1. Acta Neuropathol Commun. 2016 Feb 25; 4:16. PMID: 26916443.
      Citations: 6     Fields:    Translation:HumansAnimals
    101. Dutcher JM, Creswell JD, Pacilio LE, Harris PR, Klein WM, Levine JM, Bower JE, Muscatell KA, Eisenberger NI. Self-Affirmation Activates the Ventral Striatum: A Possible Reward-Related Mechanism for Self-Affirmation. Psychol Sci. 2016 Apr; 27(4):455-66. PMID: 26917214.
      Citations: 7     Fields:    Translation:Humans
    102. Beekman JB, Ferrer RA, Klein WM, Persky S. Effects of perceived weight discrimination on willingness to adopt unhealthy behaviours: influence of genomic information. Psychol Health. 2016; 31(3):334-48. PMID: 26406164.
      Citations: 2     Fields:    Translation:Humans
    103. Ferrer R, Klein WM. Risk perceptions and health behavior. Curr Opin Psychol. 2015 Oct 01; 5:85-89. PMID: 26258160.
      Citations: 120     Fields:    
    104. Taber JM, Howell JL, Emanuel AS, Klein WM, Ferrer RA, Harris PR. Associations of spontaneous self-affirmation with health care experiences and health information seeking in a national survey of US adults. Psychol Health. 2016; 31(3):292-309. PMID: 26315683.
      Citations: 4     Fields:    Translation:Humans
    105. Taber JM, Klein WM, Ferrer RA, Lewis KL, Harris PR, Shepperd JA, Biesecker LG. Information Avoidance Tendencies, Threat Management Resources, and Interest in Genetic Sequencing Feedback. Ann Behav Med. 2015 Aug; 49(4):616-21. PMID: 25582989.
      Citations: 17     Fields:    Translation:Humans
    106. Persoskie A, Ferrer RA, Taber JM, Klein WM, Parascandola M, Harris PR. Smoke-free air laws and quit attempts: Evidence for a moderating role of spontaneous self-affirmation. Soc Sci Med. 2015 Sep; 141:46-55. PMID: 26246033.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    107. Lewis KL, Han PK, Hooker GW, Klein WM, Biesecker LG, Biesecker BB. Characterizing Participants in the ClinSeq Genome Sequencing Cohort as Early Adopters of a New Health Technology. PLoS One. 2015; 10(7):e0132690. PMID: 26186621.
      Citations: 24     Fields:    Translation:Humans
    108. Kaufman AR, Suls JM, Klein WM. Communicating tobacco product harm: Compared to what? Addict Behav. 2016 Jan; 52:123-5. PMID: 26162963.
      Citations: 16     Fields:    Translation:HumansPHPublic Health
    109. Taber JM, Klein WM, Ferrer RA, Han PK, Lewis KL, Biesecker LG, Biesecker BB. Perceived ambiguity as a barrier to intentions to learn genome sequencing results. J Behav Med. 2015 Oct; 38(5):715-26. PMID: 26003053.
      Citations: 20     Fields:    Translation:Humans
    110. Kaufman AR, Koblitz AR, Persoskie A, Ferrer RA, Klein WM, Dwyer LA, Park ER. Factor Structure and Stability of Smoking-Related Health Beliefs in the National Lung Screening Trial. Nicotine Tob Res. 2016 Mar; 18(3):321-9. PMID: 25964503.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    111. Martinet V, Tonon S, Torres D, Azouz A, Nguyen M, Kohler A, Flamand V, Mao CA, Klein WH, Leo O, Goriely S. Type I interferons regulate eomesodermin expression and the development of unconventional memory CD8(+) T cells. Nat Commun. 2015 May 08; 6:7089. PMID: 25953241.
      Citations: 26     Fields:    Translation:AnimalsCells
    112. Wilcox KC, Marunde MR, Das A, Velasco PT, Kuhns BD, Marty MT, Jiang H, Luan CH, Sligar SG, Klein WL. Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen That Targets Binding Sites for Alzheimer's-Associated Aß Oligomers. PLoS One. 2015; 10(4):e0125263. PMID: 25928376.
      Citations: 14     Fields:    Translation:AnimalsCells
    113. Klein WM, Hamilton JG, Harris PR, Han PK. Health messaging to individuals who perceive ambiguity in health communications: the promise of self-affirmation. J Health Commun. 2015; 20(5):566-72. PMID: 25806652.
      Citations: 1     Fields:    Translation:Humans
    114. Baker-Nigh A, Vahedi S, Davis EG, Weintraub S, Bigio EH, Klein WL, Geula C. Neuronal amyloid-ß accumulation within cholinergic basal forebrain in ageing and Alzheimer's disease. Brain. 2015 Jun; 138(Pt 6):1722-37. PMID: 25732182.
      Citations: 60     Fields:    Translation:HumansCells
    115. Clarke JR, Lyra E Silva NM, Figueiredo CP, Frozza RL, Ledo JH, Beckman D, Katashima CK, Razolli D, Carvalho BM, Frazão R, Silveira MA, Ribeiro FC, Bomfim TR, Neves FS, Klein WL, Medeiros R, LaFerla FM, Carvalheira JB, Saad MJ, Munoz DP, Velloso LA, Ferreira ST, De Felice FG. Alzheimer-associated Aß oligomers impact the central nervous system to induce peripheral metabolic deregulation. EMBO Mol Med. 2015 Feb; 7(2):190-210. PMID: 25617315.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    116. Viola KL, Klein WL. Amyloid ß oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis. Acta Neuropathol. 2015 Feb; 129(2):183-206. PMID: 25604547.
      Citations: 162     Fields:    Translation:HumansAnimalsCells
    117. Viola KL, Sbarboro J, Sureka R, De M, Bicca MA, Wang J, Vasavada S, Satpathy S, Wu S, Joshi H, Velasco PT, MacRenaris K, Waters EA, Lu C, Phan J, Lacor P, Prasad P, Dravid VP, Klein WL. Towards non-invasive diagnostic imaging of early-stage Alzheimer's disease. Nat Nanotechnol. 2015 Jan; 10(1):91-8. PMID: 25531084.
      Citations: 38     Fields:    Translation:HumansAnimals
    118. Ferrer RA, Taber JM, Klein WM, Harris PR, Lewis KL, Biesecker LG. The role of current affect, anticipated affect and spontaneous self-affirmation in decisions to receive self-threatening genetic risk information. Cogn Emot. 2015; 29(8):1456-65. PMID: 25482843.
      Citations: 14     Fields:    Translation:Humans
    119. Sebollela A, Mustata GM, Luo K, Velasco PT, Viola KL, Cline EN, Shekhawat GS, Wilcox KC, Dravid VP, Klein WL. Elucidating molecular mass and shape of a neurotoxic Aß oligomer. ACS Chem Neurosci. 2014 Dec 17; 5(12):1238-45. PMID: 25343357.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    120. Knight EM, Williams HN, Stevens AC, Kim SH, Kottwitz JC, Morant AD, Steele JW, Klein WL, Yanagisawa K, Boyd RE, Lockhart DJ, Sjoberg ER, Ehrlich ME, Wustman BA, Gandy S. Evidence that small molecule enhancement of ß-hexosaminidase activity corrects the behavioral phenotype in Dutch APP(E693Q) mice through reduction of ganglioside-bound Aß. Mol Psychiatry. 2015 Feb; 20(1):109-17. PMID: 25349165.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    121. Taber JM, Klein WM, Ferrer RA, Lewis KL, Biesecker LG, Biesecker BB. Dispositional optimism and perceived risk interact to predict intentions to learn genome sequencing results. Health Psychol. 2015 Jul; 34(7):718-28. PMID: 25313897.
      Citations: 9     Fields:    Translation:Humans
    122. Forny-Germano L, Lyra e Silva NM, Batista AF, Brito-Moreira J, Gralle M, Boehnke SE, Coe BC, Lablans A, Marques SA, Martinez AM, Klein WL, Houzel JC, Ferreira ST, Munoz DP, De Felice FG. Alzheimer's disease-like pathology induced by amyloid-ß oligomers in nonhuman primates. J Neurosci. 2014 Oct 08; 34(41):13629-43. PMID: 25297091.
      Citations: 66     Fields:    Translation:AnimalsCells
    123. Han PK, Williams AE, Haskins A, Gutheil C, Lucas FL, Klein WM, Mazor KM. Individual differences in aversion to ambiguity regarding medical tests and treatments: association with cancer screening cognitions. Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12):2916-23. PMID: 25258015.
      Citations: 8     Fields:    Translation:Humans
    124. Joyal JS, Nim S, Zhu T, Sitaras N, Rivera JC, Shao Z, Sapieha P, Hamel D, Sanchez M, Zaniolo K, St-Louis M, Ouellette J, Montoya-Zavala M, Zabeida A, Picard E, Hardy P, Bhosle V, Varma DR, Gobeil F, Beauséjour C, Boileau C, Klein W, Hollenberg M, Ribeiro-da-Silva A, Andelfinger G, Chemtob S. Subcellular localization of coagulation factor II receptor-like 1 in neurons governs angiogenesis. Nat Med. 2014 Oct; 20(10):1165-73. PMID: 25216639.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    125. Klein WM, Shepperd JA, Suls J, Rothman AJ, Croyle RT. Realizing the promise of social psychology in improving public health. Pers Soc Psychol Rev. 2015 Feb; 19(1):77-92. PMID: 24981514.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    126. Heffern MC, Velasco PT, Matosziuk LM, Coomes JL, Karras C, Ratner MA, Klein WL, Eckermann AL, Meade TJ. Modulation of amyloid-ß aggregation by histidine-coordinating Cobalt(III) Schiff base complexes. Chembiochem. 2014 Jul 21; 15(11):1584-9. PMID: 24961930.
      Citations: 8     Fields:    Translation:Cells
    127. Iulita MF, Allard S, Richter L, Munter LM, Ducatenzeiler A, Weise C, Do Carmo S, Klein WL, Multhaup G, Cuello AC. Intracellular Aß pathology and early cognitive impairments in a transgenic rat overexpressing human amyloid precursor protein: a multidimensional study. Acta Neuropathol Commun. 2014 Jun 05; 2:61. PMID: 24903713.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    128. Biesecker BB, Klein W, Lewis KL, Fisher TC, Wright MF, Biesecker LG, Han PK. How do research participants perceive "uncertainty" in genome sequencing? Genet Med. 2014 Dec; 16(12):977-80. PMID: 24875302.
      Citations: 33     Fields:    Translation:Humans
    129. Gao Z, Mao CA, Pan P, Mu X, Klein WH. Transcriptome of Atoh7 retinal progenitor cells identifies new Atoh7-dependent regulatory genes for retinal ganglion cell formation. Dev Neurobiol. 2014 Nov; 74(11):1123-40. PMID: 24799426.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    130. Blair JA, Siedlak SL, Wolfram JA, Nunomura A, Castellani RJ, Ferreira ST, Klein WL, Wang Y, Casadesus G, Smith MA, Perry G, Zhu X, Lee HG. Accumulation of intraneuronal amyloid-ß is common in normal brain. Curr Alzheimer Res. 2014 May; 11(4):317-24. PMID: 24597504.
      Citations: 7     Fields:    Translation:Humans
    131. Klein WM, Ferrer RA, Graff KA, Kaufman AR, Han PK. Perceived ambiguity, fatalism, and believing cancer is more prevalent than heart disease. Am J Prev Med. 2014 Apr; 46(4):e45-7. PMID: 24650848.
      Citations: 5     Fields:    Translation:Humans
    132. Persoskie A, Ferrer RA, Nelson WL, Klein WM. Precancer risk perceptions predict postcancer subjective well-being. Health Psychol. 2014 Sep; 33(9):1023-32. PMID: 24588629.
      Citations: 6     Fields:    Translation:Humans
    133. Klein WM, Bloch M, Hesse BW, McDonald PG, Nebeling L, O'Connell ME, Riley WT, Taplin SH, Tesauro G. Behavioral research in cancer prevention and control: a look to the future. Am J Prev Med. 2014 Mar; 46(3):303-11. PMID: 24512871.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    134. Tesauro GM, Seger YR, Dijoseph L, Schnell JD, Klein WM. Assessing the value of a Small Grants Program for behavioral research in cancer control. Transl Behav Med. 2014 Mar; 4(1):79-85. PMID: 24653778.
      Citations: 2     Fields:    
    135. Harris PR, Brearley I, Sheeran P, Barker M, Klein WM, Creswell JD, Levine JM, Bond R. Combining self-affirmation with implementation intentions to promote fruit and vegetable consumption. Health Psychol. 2014 Jul; 33(7):729-36. PMID: 24490648.
      Citations: 9     Fields:    Translation:HumansAnimals
    136. Portnoy DB, Kaufman AR, Klein WM, Doyle TA, de Groot M. Cognitive and Affective Perceptions of Vulnerability as Predictors of Exercise Intentions among People with Type 2 Diabetes. J Risk Res. 2014 Jan 01; 17(2):177-193. PMID: 24563609.
      Citations: 12     
    137. Lourenco MV, Clarke JR, Frozza RL, Bomfim TR, Forny-Germano L, Batista AF, Sathler LB, Brito-Moreira J, Amaral OB, Silva CA, Freitas-Correa L, Espírito-Santo S, Campello-Costa P, Houzel JC, Klein WL, Holscher C, Carvalheira JB, Silva AM, Velloso LA, Munoz DP, Ferreira ST, De Felice FG. TNF-a mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer's ß-amyloid oligomers in mice and monkeys. Cell Metab. 2013 Dec 03; 18(6):831-43. PMID: 24315369.
      Citations: 120     Fields:    Translation:AnimalsCells
    138. Hamilton JG, Birmingham WC, Tehranifar P, Irwin ML, Klein WM, Nebeling L, Chubak J. Transitioning to independence and maintaining research careers in a new funding climate: american society of preventive oncology junior members interest group report. Cancer Epidemiol Biomarkers Prev. 2013 Nov; 22(11):2138-42. PMID: 24190867.
      Citations: 1     Fields:    Translation:Humans
    139. Napper LE, Harris PR, Klein WM. Combining self-affirmation with the extended parallel process model: the consequences for motivation to eat more fruit and vegetables. Health Commun. 2014; 29(6):610-8. PMID: 24138335.
      Citations: 5     Fields:    Translation:HumansAnimals
    140. Ehrman LA, Mu X, Waclaw RR, Yoshida Y, Vorhees CV, Klein WH, Campbell K. The LIM homeobox gene Isl1 is required for the correct development of the striatonigral pathway in the mouse. Proc Natl Acad Sci U S A. 2013 Oct 15; 110(42):E4026-35. PMID: 24082127.
      Citations: 34     Fields:    Translation:AnimalsCells
    141. Persoskie A, Ferrer RA, Klein WM. Association of cancer worry and perceived risk with doctor avoidance: an analysis of information avoidance in a nationally representative US sample. J Behav Med. 2014 Oct; 37(5):977-87. PMID: 24072430.
      Citations: 25     Fields:    Translation:Humans
    142. Kam TI, Song S, Gwon Y, Park H, Yan JJ, Im I, Choi JW, Choi TY, Kim J, Song DK, Takai T, Kim YC, Kim KS, Choi SY, Choi S, Klein WL, Yuan J, Jung YK. Fc?RIIb mediates amyloid-ß neurotoxicity and memory impairment in Alzheimer's disease. J Clin Invest. 2013 Jul; 123(7):2791-802. PMID: 23921129.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    143. Figueiredo CP, Clarke JR, Ledo JH, Ribeiro FC, Costa CV, Melo HM, Mota-Sales AP, Saraiva LM, Klein WL, Sebollela A, De Felice FG, Ferreira ST. Memantine rescues transient cognitive impairment caused by high-molecular-weight aß oligomers but not the persistent impairment induced by low-molecular-weight oligomers. J Neurosci. 2013 Jun 05; 33(23):9626-34. PMID: 23739959.
      Citations: 64     Fields:    Translation:AnimalsCells
    144. Portnoy DB, Ferrer RA, Bergman HE, Klein WM. Changing deliberative and affective responses to health risk: a meta-analysis. Health Psychol Rev. 2014; 8(3):296-318. PMID: 25053216.
      Citations: 13     Fields:    Translation:Humans
    145. Klein WM, Rothman AJ, Cameron LD. Theoretical innovations in social and personality psychology and implications for health: introduction to special issue. Health Psychol. 2013 May; 32(5):457-9. PMID: 23646830.
      Citations: 2     Fields:    Translation:Humans
    146. Creswell JD, Dutcher JM, Klein WM, Harris PR, Levine JM. Self-affirmation improves problem-solving under stress. PLoS One. 2013; 8(5):e62593. PMID: 23658751.
      Citations: 10     Fields:    Translation:Humans
    147. Nowotschin S, Costello I, Piliszek A, Kwon GS, Mao CA, Klein WH, Robertson EJ, Hadjantonakis AK. The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo. Genes Dev. 2013 May 01; 27(9):997-1002. PMID: 23651855.
      Citations: 21     Fields:    Translation:AnimalsCells
    148. Lithner CU, Lacor PN, Zhao WQ, Mustafiz T, Klein WL, Sweatt JD, Hernandez CM. Disruption of neocortical histone H3 homeostasis by soluble Aß: implications for Alzheimer's disease. Neurobiol Aging. 2013 Sep; 34(9):2081-90. PMID: 23582659.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    149. Wang J, Sun Z, Zhang Z, Saadi I, Wang J, Li X, Gao S, Engle JJ, Kuburas A, Fu X, Yu W, Klein WH, Russo AF, Amendt BA. Protein inhibitors of activated STAT (Pias1 and Piasy) differentially regulate pituitary homeobox 2 (PITX2) transcriptional activity. J Biol Chem. 2013 May 03; 288(18):12580-95. PMID: 23515314.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    150. Kondo T, Asai M, Tsukita K, Kutoku Y, Ohsawa Y, Sunada Y, Imamura K, Egawa N, Yahata N, Okita K, Takahashi K, Asaka I, Aoi T, Watanabe A, Watanabe K, Kadoya C, Nakano R, Watanabe D, Maruyama K, Hori O, Hibino S, Choshi T, Nakahata T, Hioki H, Kaneko T, Naitoh M, Yoshikawa K, Yamawaki S, Suzuki S, Hata R, Ueno S, Seki T, Kobayashi K, Toda T, Murakami K, Irie K, Klein WL, Mori H, Asada T, Takahashi R, Iwata N, Yamanaka S, Inoue H. Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aß and differential drug responsiveness. Cell Stem Cell. 2013 Apr 04; 12(4):487-96. PMID: 23434393.
      Citations: 264     Fields:    Translation:HumansCells
    151. Marty MT, Wilcox KC, Klein WL, Sligar SG. Nanodisc-solubilized membrane protein library reflects the membrane proteome. Anal Bioanal Chem. 2013 May; 405(12):4009-16. PMID: 23400332.
      Citations: 14     Fields:    Translation:Cells
    152. Mao CA, Cho JH, Wang J, Gao Z, Pan P, Tsai WW, Frishman LJ, Klein WH. Reprogramming amacrine and photoreceptor progenitors into retinal ganglion cells by replacing Neurod1 with Atoh7. Development. 2013 Feb 01; 140(3):541-51. PMID: 23293286.
      Citations: 21     Fields:    Translation:AnimalsCells
    153. Xiao C, Davis FJ, Chauhan BC, Viola KL, Lacor PN, Velasco PT, Klein WL, Chauhan NB. Brain transit and ameliorative effects of intranasally delivered anti-amyloid-ß oligomer antibody in 5XFAD mice. J Alzheimers Dis. 2013; 35(4):777-88. PMID: 23542865.
      Citations: 25     Fields:    Translation:HumansAnimals
    154. Klein WL. Synaptotoxic amyloid-ß oligomers: a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease? J Alzheimers Dis. 2013; 33 Suppl 1:S49-65. PMID: 22785404.
      Citations: 64     Fields:    Translation:HumansCells
    155. Ferrer RA, Portnoy DB, Klein WM. Worry and risk perceptions as independent and interacting predictors of health protective behaviors. J Health Commun. 2013; 18(4):397-409. PMID: 23272708.
      Citations: 27     Fields:    Translation:HumansAnimals
    156. Cho JH, Mao CA, Klein WH. Adult mice transplanted with embryonic retinal progenitor cells: new approach for repairing damaged optic nerves. Mol Vis. 2012; 18:2658-72. PMID: 23170059.
      Citations: 12     Fields:    Translation:AnimalsCells
    157. Mandal NA, Tran JT, Saadi A, Rahman AK, Huynh TP, Klein WH, Cho JH. Expression and localization of CERKL in the mammalian retina, its response to light-stress, and relationship with NeuroD1 gene. Exp Eye Res. 2013 Jan; 106:24-33. PMID: 23142158.
      Citations: 9     Fields:    Translation:AnimalsCellsPHPublic Health
    158. Velasco PT, Heffern MC, Sebollela A, Popova IA, Lacor PN, Lee KB, Sun X, Tiano BN, Viola KL, Eckermann AL, Meade TJ, Klein WL. Synapse-binding subpopulations of Aß oligomers sensitive to peptide assembly blockers and scFv antibodies. ACS Chem Neurosci. 2012 Nov 21; 3(11):972-81. PMID: 23173076.
      Citations: 18     Fields:    Translation:HumansCells
    159. Pitt J, Thorner M, Brautigan D, Larner J, Klein WL. Protection against the synaptic targeting and toxicity of Alzheimer's-associated Aß oligomers by insulin mimetic chiro-inositols. FASEB J. 2013 Jan; 27(1):199-207. PMID: 23073831.
      Citations: 14     Fields:    Translation:AnimalsCells
    160. Costa RO, Lacor PN, Ferreira IL, Resende R, Auberson YP, Klein WL, Oliveira CR, Rego AC, Pereira CM. Endoplasmic reticulum stress occurs downstream of GluN2B subunit of N-methyl-d-aspartate receptor in mature hippocampal cultures treated with amyloid-ß oligomers. Aging Cell. 2012 Oct; 11(5):823-33. PMID: 22708890.
      Citations: 27     Fields:    Translation:HumansCells
    161. Mizuguchi R, Naritsuka H, Mori K, Mao CA, Klein WH, Yoshihara Y. Tbr2 deficiency in mitral and tufted cells disrupts excitatory-inhibitory balance of neural circuitry in the mouse olfactory bulb. J Neurosci. 2012 Jun 27; 32(26):8831-44. PMID: 22745484.
      Citations: 22     Fields:    Translation:AnimalsCells
    162. Klein WM. Conducting multilevel intervention research: leveraging and looking beyond methodological advances. J Natl Cancer Inst Monogr. 2012 May; 2012(44):78-9. PMID: 22623599.
      Citations:    Fields:    Translation:Humans
    163. Shavers VL, Fagan P, Jones D, Klein WM, Boyington J, Moten C, Rorie E. The state of research on racial/ethnic discrimination in the receipt of health care. Am J Public Health. 2012 May; 102(5):953-66. PMID: 22494002.
      Citations: 97     Fields:    Translation:Humans
    164. Ferrer RA, Bergman HE, Klein WM. Worry as a predictor of nutrition behaviors: results from a nationally representative survey. Health Educ Behav. 2013 Feb; 40(1):88-96. PMID: 22505569.
      Citations: 6     Fields:    Translation:HumansAnimals
    165. Nunes-Tavares N, Santos LE, Stutz B, Brito-Moreira J, Klein WL, Ferreira ST, de Mello FG. Inhibition of choline acetyltransferase as a mechanism for cholinergic dysfunction induced by amyloid-ß peptide oligomers. J Biol Chem. 2012 Jun 01; 287(23):19377-85. PMID: 22505713.
      Citations: 37     Fields:    Translation:AnimalsCells
    166. Bomfim TR, Forny-Germano L, Sathler LB, Brito-Moreira J, Houzel JC, Decker H, Silverman MA, Kazi H, Melo HM, McClean PL, Holscher C, Arnold SE, Talbot K, Klein WL, Munoz DP, Ferreira ST, De Felice FG. An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aß oligomers. J Clin Invest. 2012 Apr; 122(4):1339-53. PMID: 22476196.
      Citations: 251     Fields:    Translation:HumansAnimalsCells
    167. Zhou Y, Klein WL. Aß oligomers-induced toxicity is attenuated in cells cultured with NbActiv4™ medium. Neurotox Res. 2012 Nov; 22(4):335-44. PMID: 22441766.
      Citations: 1     Fields:    Translation:AnimalsCells
    168. Ferrer RA, Klein WM, Zajac LE, Sutton-Tyrrell K, Muldoon MF, Kamarck TW. Unrealistic optimism is associated with subclinical atherosclerosis. Health Psychol. 2012 Nov; 31(6):815-20. PMID: 22429124.
      Citations: 4     Fields:    Translation:Humans
    169. Zou M, Li S, Klein WH, Xiang M. Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord. Dev Biol. 2012 Apr 15; 364(2):114-27. PMID: 22326227.
      Citations: 34     Fields:    Translation:AnimalsCells
    170. Umeda T, Tomiyama T, Kitajima E, Idomoto T, Nomura S, Lambert MP, Klein WL, Mori H. Hypercholesterolemia accelerates intraneuronal accumulation of Aß oligomers resulting in memory impairment in Alzheimer's disease model mice. Life Sci. 2012 Dec 10; 91(23-24):1169-76. PMID: 22273754.
      Citations: 25     Fields:    Translation:AnimalsCells
    171. Soura V, Stewart-Parker M, Williams TL, Ratnayaka A, Atherton J, Gorringe K, Tuffin J, Darwent E, Rambaran R, Klein W, Lacor P, Staras K, Thorpe J, Serpell LC. Visualization of co-localization in Aß42-administered neuroblastoma cells reveals lysosome damage and autophagosome accumulation related to cell death. Biochem J. 2012 Jan 15; 441(2):579-90. PMID: 21955321.
      Citations: 30     Fields:    Translation:HumansCells
    172. Bitel CL, Kasinathan C, Kaswala RH, Klein WL, Frederikse PH. Amyloid-ß and tau pathology of Alzheimer's disease induced by diabetes in a rabbit animal model. J Alzheimers Dis. 2012; 32(2):291-305. PMID: 22785400.
      Citations: 30     Fields:    Translation:Animals
    173. Ferrer RA, Dillard AJ, Klein WM. Projection, conformity and deviance regulation: a prospective study of alcohol use. Psychol Health. 2012; 27(6):688-703. PMID: 22172018.
      Citations: 5     Fields:    Translation:Humans
    174. Agca C, Elhajj MC, Klein WH, Venuti JM. Neurosensory and neuromuscular organization in tube feet of the sea urchin Strongylocentrotus purpuratus. J Comp Neurol. 2011 Dec 01; 519(17):3566-79. PMID: 21800307.
      Citations: 6     Fields:    Translation:AnimalsCells
    175. Han PK, Klein WM, Arora NK. Varieties of uncertainty in health care: a conceptual taxonomy. Med Decis Making. 2011 Nov-Dec; 31(6):828-38. PMID: 22067431.
      Citations: 131     Fields:    
    176. Ferreira ST, Klein WL. The Aß oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease. Neurobiol Learn Mem. 2011 Nov; 96(4):529-43. PMID: 21914486.
      Citations: 143     Fields:    Translation:HumansCells
    177. Ferrer RA, Hall KL, Portnoy DB, Ling BS, Han PK, Klein WM. Relationships among health perceptions vary depending on stage of readiness for colorectal cancer screening. Health Psychol. 2011 Sep; 30(5):525-35. PMID: 21534672.
      Citations: 22     Fields:    Translation:Humans
    178. Ferrer RA, Klein WM, Zajac LE, Land SR, Ling BS. An affective booster moderates the effect of gain- and loss-framed messages on behavioral intentions for colorectal cancer screening. J Behav Med. 2012 Aug; 35(4):452-61. PMID: 21850516.
      Citations: 15     Fields:    Translation:Humans
    179. Portnoy DB, Han PK, Ferrer RA, Klein WM, Clauser SB. Physicians' attitudes about communicating and managing scientific uncertainty differ by perceived ambiguity aversion of their patients. Health Expect. 2013 Dec; 16(4):362-72. PMID: 21838835.
      Citations: 19     Fields:    Translation:Humans
    180. Bao F, Wicklund L, Lacor PN, Klein WL, Nordberg A, Marutle A. Different ß-amyloid oligomer assemblies in Alzheimer brains correlate with age of disease onset and impaired cholinergic activity. Neurobiol Aging. 2012 Apr; 33(4):825.e1-13. PMID: 21683475.
      Citations: 44     Fields:    Translation:HumansCells
    181. Wilcox KC, Lacor PN, Pitt J, Klein WL. Aß oligomer-induced synapse degeneration in Alzheimer's disease. Cell Mol Neurobiol. 2011 Aug; 31(6):939-48. PMID: 21538118.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    182. Umeda T, Tomiyama T, Sakama N, Tanaka S, Lambert MP, Klein WL, Mori H. Intraneuronal amyloid ß oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo. J Neurosci Res. 2011 Jul; 89(7):1031-42. PMID: 21488093.
      Citations: 98     Fields:    Translation:HumansAnimalsCells
    183. Ferretti MT, Bruno MA, Ducatenzeiler A, Klein WL, Cuello AC. Intracellular Aß-oligomers and early inflammation in a model of Alzheimer's disease. Neurobiol Aging. 2012 Jul; 33(7):1329-42. PMID: 21414686.
      Citations: 47     Fields:    Translation:AnimalsCells
    184. Han PK, Klein WM, Killam B, Lehman T, Massett H, Freedman AN. Representing randomness in the communication of individualized cancer risk estimates: effects on cancer risk perceptions, worry, and subjective uncertainty about risk. Patient Educ Couns. 2012 Jan; 86(1):106-13. PMID: 21377311.
      Citations: 19     Fields:    Translation:Humans
    185. Bergman HE, Reeve BB, Moser RP, Scholl S, Klein WM. Development of a Comprehensive Heart Disease Knowledge Questionnaire. Am J Health Educ. 2011 Mar; 42(2):74-87. PMID: 21720571.
      Citations: 14     
    186. Ferretti MT, Partridge V, Leon WC, Canneva F, Allard S, Arvanitis DN, Vercauteren F, Houle D, Ducatenzeiler A, Klein WL, Glabe CG, Szyf M, Cuello AC. Transgenic mice as a model of pre-clinical Alzheimer's disease. Curr Alzheimer Res. 2011 Feb; 8(1):4-23. PMID: 21143159.
      Citations: 15     Fields:    Translation:HumansAnimals
    187. Meadows E, Flynn JM, Klein WH. Myogenin regulates exercise capacity but is dispensable for skeletal muscle regeneration in adult mdx mice. PLoS One. 2011 Jan 14; 6(1):e16184. PMID: 21264243.
      Citations: 14     Fields:    Translation:Animals
    188. Saraiva LM, Seixas da Silva GS, Galina A, da-Silva WS, Klein WL, Ferreira ST, De Felice FG. Amyloid-ß triggers the release of neuronal hexokinase 1 from mitochondria. PLoS One. 2010 Dec 16; 5(12):e15230. PMID: 21179577.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    189. Klein WM, Lipkus IM, Scholl SM, McQueen A, Cerully JL, Harris PR. Self-affirmation moderates effects of unrealistic optimism and pessimism on reactions to tailored risk feedback. Psychol Health. 2010 Dec; 25(10):1195-208. PMID: 20204982.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    190. Waters EA, Klein WM, Moser RP, Yu M, Waldron WR, McNeel TS, Freedman AN. Correlates of unrealistic risk beliefs in a nationally representative sample. J Behav Med. 2011 Jun; 34(3):225-35. PMID: 21110077.
      Citations: 23     Fields:    Translation:Humans
    191. Decker H, Jürgensen S, Adrover MF, Brito-Moreira J, Bomfim TR, Klein WL, Epstein AL, De Felice FG, Jerusalinsky D, Ferreira ST. N-methyl-D-aspartate receptors are required for synaptic targeting of Alzheimer's toxic amyloid-ß peptide oligomers. J Neurochem. 2010 Dec; 115(6):1520-9. PMID: 20950339.
      Citations: 58     Fields:    Translation:AnimalsCells
    192. Flynn JM, Meadows E, Fiorotto M, Klein WH. Myogenin regulates exercise capacity and skeletal muscle metabolism in the adult mouse. PLoS One. 2010 Oct 22; 5(10):e13535. PMID: 21042574.
      Citations: 19     Fields:    Translation:Animals
    193. Mao CA, Tsai WW, Cho JH, Pan P, Barton MC, Klein WH. Neuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell development. Dev Biol. 2011 Jan 01; 349(1):90-9. PMID: 20969844.
      Citations: 16     Fields:    Translation:AnimalsCells
    194. Kiyama T, Mao CA, Cho JH, Fu X, Pan P, Mu X, Klein WH. Overlapping spatiotemporal patterns of regulatory gene expression are required for neuronal progenitors to specify retinal ganglion cell fate. Vision Res. 2011 Jan 28; 51(2):251-9. PMID: 20951721.
      Citations: 18     Fields:    Translation:AnimalsCells
    195. Moresi V, Williams AH, Meadows E, Flynn JM, Potthoff MJ, McAnally J, Shelton JM, Backs J, Klein WH, Richardson JA, Bassel-Duby R, Olson EN. Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases. Cell. 2010 Oct 01; 143(1):35-45. PMID: 20887891.
      Citations: 178     Fields:    Translation:Animals
    196. Sessa A, Mao CA, Colasante G, Nini A, Klein WH, Broccoli V. Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons. Genes Dev. 2010 Aug 15; 24(16):1816-26. PMID: 20713522.
      Citations: 48     Fields:    Translation:AnimalsCells
    197. Nogalska A, D'Agostino C, Engel WK, Klein WL, Askanas V. Novel demonstration of amyloid-ß oligomers in sporadic inclusion-body myositis muscle fibers. Acta Neuropathol. 2010 Nov; 120(5):661-6. PMID: 20711838.
      Citations: 14     Fields:    Translation:Humans
    198. Han PK, Klein WM, Lehman T, Killam B, Massett H, Freedman AN. Communication of uncertainty regarding individualized cancer risk estimates: effects and influential factors. Med Decis Making. 2011 Mar-Apr; 31(2):354-66. PMID: 20671211.
      Citations: 32     Fields:    Translation:Humans
    199. Krafft GA, Klein WL. ADDLs and the signaling web that leads to Alzheimer's disease. Neuropharmacology. 2010 Sep-Oct; 59(4-5):230-42. PMID: 20650286.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    200. Renner M, Lacor PN, Velasco PT, Xu J, Contractor A, Klein WL, Triller A. Deleterious effects of amyloid beta oligomers acting as an extracellular scaffold for mGluR5. Neuron. 2010 Jun 10; 66(5):739-54. PMID: 20547131.
      Citations: 182     Fields:    Translation:AnimalsCells
    201. Tomiyama T, Matsuyama S, Iso H, Umeda T, Takuma H, Ohnishi K, Ishibashi K, Teraoka R, Sakama N, Yamashita T, Nishitsuji K, Ito K, Shimada H, Lambert MP, Klein WL, Mori H. A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo. J Neurosci. 2010 Apr 07; 30(14):4845-56. PMID: 20371804.
      Citations: 159     Fields:    Translation:HumansAnimalsCells
    202. Waters EA, Arora NK, Klein WM, Han PK. Perceived risk, trust and health-related quality of life among cancer survivors. Ann Behav Med. 2010 Feb; 39(1):91-7. PMID: 20333563.
      Citations: 14     Fields:    Translation:Humans
    203. Leon WC, Canneva F, Partridge V, Allard S, Ferretti MT, DeWilde A, Vercauteren F, Atifeh R, Ducatenzeiler A, Klein W, Szyf M, Alhonen L, Cuello AC. A novel transgenic rat model with a full Alzheimer's-like amyloid pathology displays pre-plaque intracellular amyloid-beta-associated cognitive impairment. J Alzheimers Dis. 2010; 20(1):113-26. PMID: 20164597.
      Citations: 60     Fields:    Translation:HumansAnimals
    204. Han PK, Moser RP, Klein WM, Beckjord EB, Dunlavy AC, Hesse BW. Predictors of perceived ambiguity about cancer prevention recommendations: sociodemographic factors and mass media exposures. Health Commun. 2009 Dec; 24(8):764-72. PMID: 20183385.
      Citations: 16     Fields:    Translation:Humans
    205. Shekhawat GS, Lambert MP, Sharma S, Velasco PT, Viola KL, Klein WL, Dravid VP. Soluble state high resolution atomic force microscopy study of Alzheimer's beta-amyloid oligomers. Appl Phys Lett. 2009 Nov 02; 95(18):183701. PMID: 19997583.
      Citations: 6     
    206. Klein WM, Harris PR. Self-affirmation enhances attentional bias toward threatening components of a persuasive message. Psychol Sci. 2009 Dec; 20(12):1463-7. PMID: 19883488.
      Citations: 11     Fields:    Translation:Humans
    207. Han PK, Reeve BB, Moser RP, Klein WM. Aversion to ambiguity regarding medical tests and treatments: measurement, prevalence, and relationship to sociodemographic factors. J Health Commun. 2009 Sep; 14(6):556-72. PMID: 19731127.
      Citations: 26     Fields:    Translation:HumansPHPublic Health
    208. Fu X, Kiyama T, Li R, Russell M, Klein WH, Mu X. Epitope-tagging Math5 and Pou4f2: new tools to study retinal ganglion cell development in the mouse. Dev Dyn. 2009 Sep; 238(9):2309-17. PMID: 19459208.
      Citations: 21     Fields:    Translation:AnimalsCells
    209. Dillard AJ, Midboe AM, Klein WM. The dark side of optimism: unrealistic optimism about problems with alcohol predicts subsequent negative event experiences. Pers Soc Psychol Bull. 2009 Nov; 35(11):1540-50. PMID: 19721102.
      Citations: 22     Fields:    Translation:Humans
    210. Pitt J, Roth W, Lacor P, Smith AB, Blankenship M, Velasco P, De Felice F, Breslin P, Klein WL. Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. Toxicol Appl Pharmacol. 2009 Oct 15; 240(2):189-97. PMID: 19631677.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    211. Peng S, Garzon DJ, Marchese M, Klein W, Ginsberg SD, Francis BM, Mount HT, Mufson EJ, Salehi A, Fahnestock M. Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease. J Neurosci. 2009 Jul 22; 29(29):9321-9. PMID: 19625522.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    212. Kiyota T, Yamamoto M, Xiong H, Lambert MP, Klein WL, Gendelman HE, Ransohoff RM, Ikezu T. CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction. PLoS One. 2009 Jul 10; 4(7):e6197. PMID: 19593388.
      Citations: 52     Fields:    Translation:AnimalsCells
    213. Kiyama T, Zhang J, Liang S, Liang S, Klein WH. Intragenomic evolution of a transcriptional enhancer in the genome of Strongylocentrotus purpuratus. Mar Genomics. 2009 Jun; 2(2):85-98. PMID: 21798176.
      Citations:    Fields:    
    214. Agca C, Klein WH, Venuti JM. Reduced O2 and elevated ROS in sea urchin embryos leads to defects in ectoderm differentiation. Dev Dyn. 2009 Jul; 238(7):1777-87. PMID: 19517573.
      Citations: 3     Fields:    Translation:AnimalsCells
    215. Han PK, Klein WM, Lehman TC, Massett H, Lee SC, Freedman AN. Laypersons' responses to the communication of uncertainty regarding cancer risk estimates. Med Decis Making. 2009 May-Jun; 29(3):391-403. PMID: 19470720.
      Citations: 27     Fields:    Translation:Humans
    216. Zhao WQ, Lacor PN, Chen H, Lambert MP, Quon MJ, Krafft GA, Klein WL. Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}. J Biol Chem. 2009 Jul 10; 284(28):18742-53. PMID: 19406747.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    217. Lu R, Vidal GS, Kelly JA, Delgado-Vega AM, Howard XK, Macwana SR, Dominguez N, Klein W, Burrell C, Harley IT, Kaufman KM, Bruner GR, Moser KL, Gaffney PM, Gilkeson GS, Wakeland EK, Li QZ, Langefeld CD, Marion MC, Divers J, Alarcón GS, Brown EE, Kimberly RP, Edberg JC, Ramsey-Goldman R, Reveille JD, McGwin G, Vilá LM, Petri MA, Bae SC, Cho SK, Bang SY, Kim I, Choi CB, Martin J, Vyse TJ, Merrill JT, Harley JB, Alarcón-Riquelme ME, Nath SK, James JA, Guthridge JM. Genetic associations of LYN with systemic lupus erythematosus. Genes Immun. 2009 Jul; 10(5):397-403. PMID: 19369946.
      Citations: 51     Fields:    Translation:Humans
    218. Guo L, Deshmukh H, Lu R, Vidal GS, Kelly JA, Kaufman KM, Dominguez N, Klein W, Kim-Howard X, Bruner GR, Scofield RH, Moser KL, Gaffney PM, Dozmorov IM, Gilkeson GS, Wakeland EK, Li QZ, Langefeld CD, Marion MC, Williams AH, Divers J, Alarcón GS, Brown EE, Kimberly RP, Edberg JC, Ramsey-Goldman R, Reveille JD, McGwin G, Vilá LM, Petri MA, Vyse TJ, Merrill JT, James JA, Nath SK, Harley JB, Guthridge JM. Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population. Genes Immun. 2009 Jul; 10(5):531-8. PMID: 19339986.
      Citations: 12     Fields:    Translation:Humans
    219. Anker JN, Hall WP, Lambert MP, Velasco PT, Mrksich M, Klein WL, Van Duyne RP. Detection and Identification of Bioanalytes with High Resolution LSPR Spectroscopy and MALDI Mass Spectrometry. J Phys Chem C Nanomater Interfaces. 2009 Mar 24; 113(15):5891-5894. PMID: 20161175.
      Citations: 10     
    220. Kiyota T, Yamamoto M, Schroder B, Jacobsen MT, Swan RJ, Lambert MP, Klein WL, Gendelman HE, Ransohoff RM, Ikezu T. AAV1/2-mediated CNS gene delivery of dominant-negative CCL2 mutant suppresses gliosis, beta-amyloidosis, and learning impairment of APP/PS1 mice. Mol Ther. 2009 May; 17(5):803-9. PMID: 19277012.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    221. Han PK, Lehman TC, Massett H, Lee SJ, Klein WM, Freedman AN. Conceptual problems in laypersons' understanding of individualized cancer risk: a qualitative study. Health Expect. 2009 Mar; 12(1):4-17. PMID: 19250148.
      Citations: 24     Fields:    Translation:Humans
    222. Lambert MP, Velasco PT, Viola KL, Klein WL. Targeting generation of antibodies specific to conformational epitopes of amyloid beta-derived neurotoxins. CNS Neurol Disord Drug Targets. 2009 Mar; 8(1):65-81. PMID: 19275637.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    223. De Felice FG, Vieira MN, Bomfim TR, Decker H, Velasco PT, Lambert MP, Viola KL, Zhao WQ, Ferreira ST, Klein WL. Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. Proc Natl Acad Sci U S A. 2009 Feb 10; 106(6):1971-6. PMID: 19188609.
      Citations: 224     Fields:    Translation:HumansAnimalsCells
    224. Agca C, Klein WH, Venuti JM. Respecification of ectoderm and altered Nodal expression in sea urchin embryos after cobalt and nickel treatment. Mech Dev. 2009 May-Jun; 126(5-6):430-42. PMID: 19368800.
      Citations: 3     Fields:    Translation:AnimalsCells
    225. Nishitsuji K, Tomiyama T, Ishibashi K, Ito K, Teraoka R, Lambert MP, Klein WL, Mori H. The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells. Am J Pathol. 2009 Mar; 174(3):957-69. PMID: 19164507.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    226. Wang XP, Zhang JH, Wang YJ, Feng Y, Zhang X, Sun XX, Li JL, Du XT, Lambert MP, Yang SG, Zhao M, Klein WL, Liu RT. Conformation-dependent single-chain variable fragment antibodies specifically recognize beta-amyloid oligomers. FEBS Lett. 2009 Feb 04; 583(3):579-84. PMID: 19162022.
      Citations: 21     Fields:    Translation:HumansCells
    227. Tchantchou F, Lacor PN, Cao Z, Lao L, Hou Y, Cui C, Klein WL, Luo Y. Stimulation of neurogenesis and synaptogenesis by bilobalide and quercetin via common final pathway in hippocampal neurons. J Alzheimers Dis. 2009; 18(4):787-98. PMID: 19661619.
      Citations: 44     Fields:    Translation:AnimalsCells
    228. Tang H, Macpherson P, Marvin M, Meadows E, Klein WH, Yang XJ, Goldman D. A histone deacetylase 4/myogenin positive feedback loop coordinates denervation-dependent gene induction and suppression. Mol Biol Cell. 2009 Feb; 20(4):1120-31. PMID: 19109424.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    229. Cho JH, Mu X, Wang SW, Klein WH. Retinal ganglion cell death and optic nerve degeneration by genetic ablation in adult mice. Exp Eye Res. 2009 Mar; 88(3):542-52. PMID: 19109949.
      Citations: 6     Fields:    Translation:AnimalsCells
    230. Sessa A, Mao CA, Hadjantonakis AK, Klein WH, Broccoli V. Tbr2 directs conversion of radial glia into basal precursors and guides neuronal amplification by indirect neurogenesis in the developing neocortex. Neuron. 2008 Oct 09; 60(1):56-69. PMID: 18940588.
      Citations: 183     Fields:    Translation:AnimalsCells
    231. Sapieha P, Sirinyan M, Hamel D, Zaniolo K, Joyal JS, Cho JH, Honoré JC, Kermorvant-Duchemin E, Varma DR, Tremblay S, Leduc M, Rihakova L, Hardy P, Klein WH, Mu X, Mamer O, Lachapelle P, Di Polo A, Beauséjour C, Andelfinger G, Mitchell G, Sennlaub F, Chemtob S. The succinate receptor GPR91 in neurons has a major role in retinal angiogenesis. Nat Med. 2008 Oct; 14(10):1067-76. PMID: 18836459.
      Citations: 127     Fields:    Translation:AnimalsCells
    232. Mao CA, Wang SW, Pan P, Klein WH. Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5. Development. 2008 Oct; 135(20):3379-88. PMID: 18787067.
      Citations: 22     Fields:    Translation:AnimalsCells
    233. Wu Y, Cao Z, Klein WL, Luo Y. Heat shock treatment reduces beta amyloid toxicity in vivo by diminishing oligomers. Neurobiol Aging. 2010 Jun; 31(6):1055-8. PMID: 18762355.
      Citations: 14     Fields:    Translation:HumansAnimals
    234. Meadows E, Cho JH, Flynn JM, Klein WH. Myogenin regulates a distinct genetic program in adult muscle stem cells. Dev Biol. 2008 Oct 15; 322(2):406-14. PMID: 18721801.
      Citations: 40     Fields:    Translation:AnimalsCells
    235. Gramling R, Klein W, Roberts M, Waring ME, Gramling D, Eaton CB. Self-rated cardiovascular risk and 15-year cardiovascular mortality. Ann Fam Med. 2008 Jul-Aug; 6(4):302-6. PMID: 18626029.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    236. Mu X, Fu X, Beremand PD, Thomas TL, Klein WH. Gene regulation logic in retinal ganglion cell development: Isl1 defines a critical branch distinct from but overlapping with Pou4f2. Proc Natl Acad Sci U S A. 2008 May 13; 105(19):6942-7. PMID: 18460603.
      Citations: 79     Fields:    Translation:AnimalsCells
    237. Hirata-Fukae C, Li HF, Hoe HS, Gray AJ, Minami SS, Hamada K, Niikura T, Hua F, Tsukagoshi-Nagai H, Horikoshi-Sakuraba Y, Mughal M, Rebeck GW, LaFerla FM, Mattson MP, Iwata N, Saido TC, Klein WL, Duff KE, Aisen PS, Matsuoka Y. Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model. Brain Res. 2008 Jun 24; 1216:92-103. PMID: 18486110.
      Citations: 109     Fields:    Translation:Animals
    238. McKee AC, Carreras I, Hossain L, Ryu H, Klein WL, Oddo S, LaFerla FM, Jenkins BG, Kowall NW, Dedeoglu A. Ibuprofen reduces Abeta, hyperphosphorylated tau and memory deficits in Alzheimer mice. Brain Res. 2008 May 01; 1207:225-36. PMID: 18374906.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    239. Viola KL, Velasco PT, Klein WL. Why Alzheimer's is a disease of memory: the attack on synapses by A beta oligomers (ADDLs). J Nutr Health Aging. 2008 Jan; 12(1):51S-7S. PMID: 18165846.
      Citations: 35     Fields:    Translation:HumansCells
    240. Mao CA, Kiyama T, Pan P, Furuta Y, Hadjantonakis AK, Klein WH. Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse. Development. 2008 Jan; 135(2):271-80. PMID: 18077589.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    241. Han PK, Moser RP, Klein WM. Perceived ambiguity about cancer prevention recommendations: associations with cancer-related perceptions and behaviours in a US population survey. Health Expect. 2007 Dec; 10(4):321-36. PMID: 17986069.
      Citations: 37     Fields:    Translation:Humans
    242. Klein W, Geaghan T, Macdonald T. Unplanned sexual activity as a consequence of alcohol use: a prospective study of risk perceptions and alcohol use among college freshmen. J Am Coll Health. 2007 Nov-Dec; 56(3):317-23. PMID: 18089515.
      Citations: 6     Fields:    Translation:Humans
    243. Durairajan SS, Yuan Q, Xie L, Chan WS, Kum WF, Koo I, Liu C, Song Y, Huang JD, Klein WL, Li M. Salvianolic acid B inhibits Abeta fibril formation and disaggregates preformed fibrils and protects against Abeta-induced cytotoxicty. Neurochem Int. 2008 Mar-Apr; 52(4-5):741-50. PMID: 17964692.
      Citations: 28     Fields:    Translation:HumansCells
    244. Zhao WQ, De Felice FG, Fernandez S, Chen H, Lambert MP, Quon MJ, Krafft GA, Klein WL. Amyloid beta oligomers induce impairment of neuronal insulin receptors. FASEB J. 2008 Jan; 22(1):246-60. PMID: 17720802.
      Citations: 200     Fields:    Translation:HumansAnimalsCells
    245. Kiyama T, Klein WH. SpGataE, a Strongylocentrotus purpuratus ortholog of mammalian Gata4/5/6: protein expression, interaction with putative target gene spec2a, and identification of friend of Gata factor SpFog1. Dev Genes Evol. 2007 Sep; 217(9):651-63. PMID: 17710433.
      Citations: 2     Fields:    Translation:AnimalsCells
    246. Davie JK, Cho JH, Meadows E, Flynn JM, Knapp JR, Klein WH. Target gene selectivity of the myogenic basic helix-loop-helix transcription factor myogenin in embryonic muscle. Dev Biol. 2007 Nov 15; 311(2):650-64. PMID: 17904117.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    247. Rishniw M, Fisher PW, Doran RM, Meadows E, Klein WH, Kotlikoff MI. Smooth muscle persists in the muscularis externa of developing and adult mouse esophagus. J Muscle Res Cell Motil. 2007; 28(2-3):153-65. PMID: 17638088.
      Citations: 8     Fields:    Translation:AnimalsCells
    248. De Felice FG, Wasilewska-Sampaio AP, Barbosa AC, Gomes FC, Klein WL, Ferreira ST. Cyclic AMP enhancers and Abeta oligomerization blockers as potential therapeutic agents in Alzheimer's disease. Curr Alzheimer Res. 2007 Jul; 4(3):263-71. PMID: 17627483.
      Citations: 13     Fields:    Translation:HumansAnimals
    249. Cho JH, Klein WH, Tsai MJ. Compensational regulation of bHLH transcription factors in the postnatal development of BETA2/NeuroD1-null retina. Mech Dev. 2007 Aug; 124(7-8):543-50. PMID: 17629466.
      Citations: 9     Fields:    Translation:AnimalsCells
    250. Ai D, Fu X, Wang J, Lu MF, Chen L, Baldini A, Klein WH, Martin JF. Canonical Wnt signaling functions in second heart field to promote right ventricular growth. Proc Natl Acad Sci U S A. 2007 May 29; 104(22):9319-24. PMID: 17519332.
      Citations: 83     Fields:    Translation:AnimalsCells
    251. De Felice FG, Wu D, Lambert MP, Fernandez SJ, Velasco PT, Lacor PN, Bigio EH, Jerecic J, Acton PJ, Shughrue PJ, Chen-Dodson E, Kinney GG, Klein WL. Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers. Neurobiol Aging. 2008 Sep; 29(9):1334-47. PMID: 17403556.
      Citations: 171     Fields:    Translation:HumansCells
    252. Han PK, Kobrin SC, Klein WM, Davis WW, Stefanek M, Taplin SH. Perceived ambiguity about screening mammography recommendations: association with future mammography uptake and perceptions. Cancer Epidemiol Biomarkers Prev. 2007 Mar; 16(3):458-66. PMID: 17372241.
      Citations: 32     Fields:    Translation:Humans
    253. De Felice FG, Velasco PT, Lambert MP, Viola K, Fernandez SJ, Ferreira ST, Klein WL. Abeta oligomers induce neuronal oxidative stress through an N-methyl-D-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine. J Biol Chem. 2007 Apr 13; 282(15):11590-601. PMID: 17308309.
      Citations: 347     Fields:    Translation:AnimalsCells
    254. Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, Wood M, Viola KL, Klein WL. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J Neurosci. 2007 Jan 24; 27(4):796-807. PMID: 17251419.
      Citations: 479     Fields:    Translation:AnimalsCells
    255. Wu Y, Wu Z, Butko P, Christen Y, Lambert MP, Klein WL, Link CD, Luo Y. Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans. J Neurosci. 2006 Dec 13; 26(50):13102-13. PMID: 17167099.
      Citations: 113     Fields:    Translation:Animals
    256. Lambert MP, Velasco PT, Chang L, Viola KL, Fernandez S, Lacor PN, Khuon D, Gong Y, Bigio EH, Shaw P, De Felice FG, Krafft GA, Klein WL. Monoclonal antibodies that target pathological assemblies of Abeta. J Neurochem. 2007 Jan; 100(1):23-35. PMID: 17116235.
      Citations: 134     Fields:    Translation:HumansAnimalsCells
    257. Sodergren E, Weinstock GM, Davidson EH, Cameron RA, Gibbs RA, Angerer RC, Angerer LM, Arnone MI, Burgess DR, Burke RD, Coffman JA, Dean M, Elphick MR, Ettensohn CA, Foltz KR, Hamdoun A, Hynes RO, Klein WH, Marzluff W, McClay DR, Morris RL, Mushegian A, Rast JP, Smith LC, Thorndyke MC, Vacquier VD, Wessel GM, Wray G, Zhang L, Elsik CG, Ermolaeva O, Hlavina W, Hofmann G, Kitts P, Landrum MJ, Mackey AJ, Maglott D, Panopoulou G, Poustka AJ, Pruitt K, Sapojnikov V, Song X, Souvorov A, Solovyev V, Wei Z, Whittaker CA, Worley K, Durbin KJ, Shen Y, Fedrigo O, Garfield D, Haygood R, Primus A, Satija R, Severson T, Gonzalez-Garay ML, Jackson AR, Milosavljevic A, Tong M, Killian CE, Livingston BT, Wilt FH, Adams N, Bellé R, Carbonneau S, Cheung R, Cormier P, Cosson B, Croce J, Fernandez-Guerra A, Genevière AM, Goel M, Kelkar H, Morales J, Mulner-Lorillon O, Robertson AJ, Goldstone JV, Cole B, Epel D, Gold B, Hahn ME, Howard-Ashby M, Scally M, Stegeman JJ, Allgood EL, Cool J, Judkins KM, McCafferty SS, Musante AM, Obar RA, Rawson AP, Rossetti BJ, Gibbons IR, Hoffman MP, Leone A, Istrail S, Materna SC, Samanta MP, Stolc V, Tongprasit W, Tu Q, Bergeron KF, Brandhorst BP, Whittle J, Berney K, Bottjer DJ, Calestani C, Peterson K, Chow E, Yuan QA, Elhaik E, Graur D, Reese JT, Bosdet I, Heesun S, Marra MA, Schein J, Anderson MK, Brockton V, Buckley KM, Cohen AH, Fugmann SD, Hibino T, Loza-Coll M, Majeske AJ, Messier C, Nair SV, Pancer Z, Terwilliger DP, Agca C, Arboleda E, Chen N, Churcher AM, Hallböök F, Humphrey GW, Idris MM, Kiyama T, Liang S, Mellott D, Mu X, Murray G, Olinski RP, Raible F, Rowe M, Taylor JS, Tessmar-Raible K, Wang D, Wilson KH, Yaguchi S, Gaasterland T, Galindo BE, Gunaratne HJ, Juliano C, Kinukawa M, Moy GW, Neill AT, Nomura M, Raisch M, Reade A, Roux MM, Song JL, Su YH, Townley IK, Voronina E, Wong JL, Amore G, Branno M, Brown ER, Cavalieri V, Duboc V, Duloquin L, Flytzanis C, Gache C, Lapraz F, Lepage T, Locascio A, Martinez P, Matassi G, Matranga V, Range R, Rizzo F, Röttinger E, Beane W, Bradham C, Byrum C, Glenn T, Hussain S, Manning G, Miranda E, Thomason R, Walton K, Wikramanayke A, Wu SY, Xu R, Brown CT, Chen L, Gray RF, Lee PY, Nam J, Oliveri P, Smith J, Muzny D, Bell S, Chacko J, Cree A, Curry S, Davis C, Dinh H, Dugan-Rocha S, Fowler J, Gill R, Hamilton C, Hernandez J, Hines S, Hume J, Jackson L, Jolivet A, Kovar C, Lee S, Lewis L, Miner G, Morgan M, Nazareth LV, Okwuonu G, Parker D, Pu LL, Thorn R, Wright R. The genome of the sea urchin Strongylocentrotus purpuratus. Science. 2006 Nov 10; 314(5801):941-52. PMID: 17095691.
      Citations: 368     Fields:    Translation:AnimalsCells
    258. Burke RD, Angerer LM, Elphick MR, Humphrey GW, Yaguchi S, Kiyama T, Liang S, Mu X, Agca C, Klein WH, Brandhorst BP, Rowe M, Wilson K, Churcher AM, Taylor JS, Chen N, Murray G, Wang D, Mellott D, Olinski R, Hallböök F, Thorndyke MC. A genomic view of the sea urchin nervous system. Dev Biol. 2006 Dec 01; 300(1):434-60. PMID: 16965768.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    259. Fu X, Sun H, Klein WH, Mu X. Beta-catenin is essential for lamination but not neurogenesis in mouse retinal development. Dev Biol. 2006 Nov 15; 299(2):424-37. PMID: 16959241.
      Citations: 45     Fields:    Translation:AnimalsCells
    260. Boutaud O, Montine TJ, Chang L, Klein WL, Oates JA. PGH2-derived levuglandin adducts increase the neurotoxicity of amyloid beta1-42. J Neurochem. 2006 Feb; 96(4):917-23. PMID: 16412101.
      Citations: 24     Fields:    Translation:AnimalsCells
    261. Knapp JR, Davie JK, Myer A, Meadows E, Olson EN, Klein WH. Loss of myogenin in postnatal life leads to normal skeletal muscle but reduced body size. Development. 2006 Feb; 133(4):601-10. PMID: 16407395.
      Citations: 50     Fields:    Translation:AnimalsCells
    262. Ohno M, Chang L, Tseng W, Oakley H, Citron M, Klein WL, Vassar R, Disterhoft JF. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1. Eur J Neurosci. 2006 Jan; 23(1):251-60. PMID: 16420434.
      Citations: 113     Fields:    Translation:Animals
    263. Klein WL. Synaptic targeting by A beta oligomers (ADDLS) as a basis for memory loss in early Alzheimer's disease. Alzheimers Dement. 2006 Jan; 2(1):43-55. PMID: 19595855.
      Citations: 38     Fields:    
    264. Dillard AJ, McCaul KD, Kelso PD, Klein WM. Resisting good news: reactions to breast cancer risk communication. Health Commun. 2006; 19(2):115-23. PMID: 16548702.
      Citations: 14     Fields:    Translation:Humans
    265. Han PK, Moser RP, Klein WM. Perceived ambiguity about cancer prevention recommendations: relationship to perceptions of cancer preventability, risk, and worry. J Health Commun. 2006; 11 Suppl 1:51-69. PMID: 16641074.
      Citations: 48     Fields:    Translation:Humans
    266. Dillard AJ, McCaul KD, Klein WM. Unrealistic optimism in smokers: implications for smoking myth endorsement and self-protective motivation. J Health Commun. 2006; 11 Suppl 1:93-102. PMID: 16641076.
      Citations: 50     Fields:    Translation:Humans
    267. Oddo S, Caccamo A, Tran L, Lambert MP, Glabe CG, Klein WL, LaFerla FM. Temporal profile of amyloid-beta (Abeta) oligomerization in an in vivo model of Alzheimer disease. A link between Abeta and tau pathology. J Biol Chem. 2006 Jan 20; 281(3):1599-604. PMID: 16282321.
      Citations: 151     Fields:    Translation:HumansAnimalsCells
    268. Villinski JT, Kiyama T, Dayal S, Zhang N, Liang S, Klein WH. Structure, expression, and transcriptional regulation of the Strongylocentrotus franciscanus spec gene family encoding intracellular calcium-binding proteins. Dev Genes Evol. 2005 Aug; 215(8):410-22. PMID: 15871032.
      Citations: 2     Fields:    Translation:AnimalsCells
    269. Kiyama T, Zhang N, Dayal S, Yun Lee P, Liang S, Villinski JT, Klein WH. Strongylocentrotus purpuratus transcription factor GATA-E binds to and represses transcription at an Otx-Goosecoid cis-regulatory element within the aboral ectoderm-specific spec2a enhancer. Dev Biol. 2005 Apr 15; 280(2):436-47. PMID: 15882584.
      Citations: 3     Fields:    Translation:AnimalsCells
    270. Mu X, Fu X, Sun H, Beremand PD, Thomas TL, Klein WH. A gene network downstream of transcription factor Math5 regulates retinal progenitor cell competence and ganglion cell fate. Dev Biol. 2005 Apr 15; 280(2):467-81. PMID: 15882586.
      Citations: 65     Fields:    Translation:AnimalsCells
    271. Mu X, Fu X, Sun H, Liang S, Maeda H, Frishman LJ, Klein WH. Ganglion cells are required for normal progenitor- cell proliferation but not cell-fate determination or patterning in the developing mouse retina. Curr Biol. 2005 Mar 29; 15(6):525-30. PMID: 15797020.
      Citations: 40     Fields:    Translation:AnimalsCells
    272. Haes AJ, Chang L, Klein WL, Van Duyne RP. Detection of a biomarker for Alzheimer's disease from synthetic and clinical samples using a nanoscale optical biosensor. J Am Chem Soc. 2005 Feb 23; 127(7):2264-71. PMID: 15713105.
      Citations: 99     Fields:    Translation:Humans
    273. Georganopoulou DG, Chang L, Nam JM, Thaxton CS, Mufson EJ, Klein WL, Mirkin CA. Nanoparticle-based detection in cerebral spinal fluid of a soluble pathogenic biomarker for Alzheimer's disease. Proc Natl Acad Sci U S A. 2005 Feb 15; 102(7):2273-6. PMID: 15695586.
      Citations: 152     Fields:    Translation:HumansCells
    274. Martin SE, Mu X, Klein WH. Identification of an N-terminal transcriptional activation domain within Brn3b/POU4f2. Differentiation. 2005 Feb; 73(1):18-27. PMID: 15733064.
      Citations: 2     Fields:    Translation:AnimalsCells
    275. Lacor PN, Buniel MC, Chang L, Fernandez SJ, Gong Y, Viola KL, Lambert MP, Velasco PT, Bigio EH, Finch CE, Krafft GA, Klein WL. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. J Neurosci. 2004 Nov 10; 24(45):10191-200. PMID: 15537891.
      Citations: 366     Fields:    Translation:HumansAnimalsCells
    276. Liang S, Zhao S, Mu X, Thomas T, Klein WH. Novel retinal genes discovered by mining the mouse embryonic RetinalExpress database. Mol Vis. 2004 Oct 08; 10:773-86. PMID: 15496829.
      Citations: 2     Fields:    Translation:Animals
    277. Dayal S, Kiyama T, Villinski JT, Zhang N, Liang S, Klein WH. Creation of cis-regulatory elements during sea urchin evolution by co-option and optimization of a repetitive sequence adjacent to the spec2a gene. Dev Biol. 2004 Sep 15; 273(2):436-53. PMID: 15328024.
      Citations: 9     Fields:    Translation:AnimalsCells
    278. Wikramanayake AH, Peterson R, Chen J, Huang L, Bince JM, McClay DR, Klein WH. Nuclear beta-catenin-dependent Wnt8 signaling in vegetal cells of the early sea urchin embryo regulates gastrulation and differentiation of endoderm and mesodermal cell lineages. Genesis. 2004 Jul; 39(3):194-205. PMID: 15282746.
      Citations: 46     Fields:    Translation:AnimalsCells
    279. Wang Z, Chang L, Klein WL, Thatcher GR, Venton DL. Per-6-substituted-per-6-deoxy beta-cyclodextrins inhibit the formation of beta-amyloid peptide derived soluble oligomers. J Med Chem. 2004 Jun 17; 47(13):3329-33. PMID: 15189029.
      Citations: 10     Fields:    
    280. Klein WL, Stine WB, Teplow DB. Small assemblies of unmodified amyloid beta-protein are the proximate neurotoxin in Alzheimer's disease. Neurobiol Aging. 2004 May-Jun; 25(5):569-80. PMID: 15172732.
      Citations: 152     Fields:    Translation:HumansAnimalsCells
    281. Bleijerveld OB, Klein W, Vaandrager AB, Helms JB, Houweling M. Control of the CDPethanolamine pathway in mammalian cells: effect of CTP:phosphoethanolamine cytidylyltransferase overexpression and the amount of intracellular diacylglycerol. Biochem J. 2004 May 01; 379(Pt 3):711-9. PMID: 14759225.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    282. Ohtoshi A, Wang SW, Maeda H, Saszik SM, Frishman LJ, Klein WH, Behringer RR. Regulation of retinal cone bipolar cell differentiation and photopic vision by the CVC homeobox gene Vsx1. Curr Biol. 2004 Mar 23; 14(6):530-6. PMID: 15043821.
      Citations: 47     Fields:    Translation:AnimalsCells
    283. Mu X, Beremand PD, Zhao S, Pershad R, Sun H, Scarpa A, Liang S, Thomas TL, Klein WH. Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina. Development. 2004 Mar; 131(6):1197-210. PMID: 14973295.
      Citations: 57     Fields:    Translation:AnimalsCells
    284. Mu X, Klein WH. A gene regulatory hierarchy for retinal ganglion cell specification and differentiation. Semin Cell Dev Biol. 2004 Feb; 15(1):115-23. PMID: 15036214.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    285. Chromy BA, Nowak RJ, Lambert MP, Viola KL, Chang L, Velasco PT, Jones BW, Fernandez SJ, Lacor PN, Horowitz P, Finch CE, Krafft GA, Klein WL. Self-assembly of Abeta(1-42) into globular neurotoxins. Biochemistry. 2003 Nov 11; 42(44):12749-60. PMID: 14596589.
      Citations: 155     Fields:    Translation:HumansAnimalsCells
    286. Moscucci M, Fox KA, Cannon CP, Klein W, López-Sendón J, Montalescot G, White K, Goldberg RJ. Predictors of major bleeding in acute coronary syndromes: the Global Registry of Acute Coronary Events (GRACE). Eur Heart J. 2003 Oct; 24(20):1815-23. PMID: 14563340.
      Citations: 133     Fields:    Translation:Humans
    287. Gong Y, Chang L, Viola KL, Lacor PN, Lambert MP, Finch CE, Krafft GA, Klein WL. Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss. Proc Natl Acad Sci U S A. 2003 Sep 02; 100(18):10417-22. PMID: 12925731.
      Citations: 334     Fields:    Translation:AnimalsCells
    288. Chang L, Bakhos L, Wang Z, Venton DL, Klein WL. Femtomole immunodetection of synthetic and endogenous amyloid-beta oligomers and its application to Alzheimer's disease drug candidate screening. J Mol Neurosci. 2003; 20(3):305-13. PMID: 14501013.
      Citations: 25     Fields:    Translation:AnimalsCells
    289. Wang SW, Mu X, Bowers WJ, Klein WH. Retinal ganglion cell differentiation in cultured mouse retinal explants. Methods. 2002 Dec; 28(4):448-56. PMID: 12507463.
      Citations: 14     Fields:    Translation:AnimalsCells
    290. Kim HJ, Chae SC, Lee DK, Chromy B, Lee SC, Park YC, Klein WL, Krafft GA, Hong ST. Selective neuronal degeneration induced by soluble oligomeric amyloid beta protein. FASEB J. 2003 Jan; 17(1):118-20. PMID: 12424218.
      Citations: 53     Fields:    Translation:AnimalsCells
    291. Klein WL. Abeta toxicity in Alzheimer's disease: globular oligomers (ADDLs) as new vaccine and drug targets. Neurochem Int. 2002 Nov; 41(5):345-52. PMID: 12176077.
      Citations: 192     Fields:    Translation:HumansAnimalsCells
    292. Yu J, Bakhos L, Chang L, Holterman MJ, Klein WL, Venton DL. Per-6-substituted beta-cyclodextrin libraries inhibit formation of beta-amyloid-peptide (A beta)-derived, soluble oligomers. J Mol Neurosci. 2002 Aug-Oct; 19(1-2):51-5. PMID: 12212793.
      Citations: 4     Fields:    Translation:Animals
    293. Li X, Bhattacharya C, Dayal S, Maity S, Klein WH. Ectoderm gene activation in sea urchin embryos mediated by the CCAAT-binding factor. Differentiation. 2002 May; 70(2-3):109-19. PMID: 12076338.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    294. Klein WL. ADDLs & protofibrils--the missing links? Neurobiol Aging. 2002 Mar-Apr; 23(2):231-5. PMID: 11804707.
      Citations: 25     Fields:    Translation:HumansCells
    295. Houweling M, Klein W, Geelen MJ. Regulation of phosphatidylcholine and phosphatidylethanolamine synthesis in rat hepatocytes by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR). Biochem J. 2002 Feb 15; 362(Pt 1):97-104. PMID: 11829744.
      Citations: 5     Fields:    Translation:AnimalsCells
    296. Wang HW, Pasternak JF, Kuo H, Ristic H, Lambert MP, Chromy B, Viola KL, Klein WL, Stine WB, Krafft GA, Trommer BL. Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus. Brain Res. 2002 Jan 11; 924(2):133-40. PMID: 11750898.
      Citations: 184     Fields:    Translation:AnimalsCells
    297. Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH. Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development. 2002 Jan; 129(2):467-77. PMID: 11807038.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    298. Brandhorst BP, Klein WH. Molecular patterning along the sea urchin animal-vegetal axis. Int Rev Cytol. 2002; 213:183-232. PMID: 11837893.
      Citations: 8     Fields:    Translation:Animals
    299. Mu X, Zhao S, Pershad R, Hsieh TF, Scarpa A, Wang SW, White RA, Beremand PD, Thomas TL, Gan L, Klein WH. Gene expression in the developing mouse retina by EST sequencing and microarray analysis. Nucleic Acids Res. 2001 Dec 15; 29(24):4983-93. PMID: 11812828.
      Citations: 27     Fields:    Translation:AnimalsCells
    300. Angerer LM, Oleksyn DW, Levine AM, Li X, Klein WH, Angerer RC. Sea urchin goosecoid function links fate specification along the animal-vegetal and oral-aboral embryonic axes. Development. 2001 Nov; 128(22):4393-404. PMID: 11714666.
      Citations: 24     Fields:    Translation:AnimalsCells
    301. Lambert MP, Viola KL, Chromy BA, Chang L, Morgan TE, Yu J, Venton DL, Krafft GA, Finch CE, Klein WL. Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies. J Neurochem. 2001 Nov; 79(3):595-605. PMID: 11701763.
      Citations: 107     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    302. Sumariwalla VM, Klein WH. Similar myogenic functions for myogenin and MRF4 but not MyoD in differentiated murine embryonic stem cells. Genesis. 2001 Aug; 30(4):239-49. PMID: 11536430.
      Citations: 7     Fields:    Translation:AnimalsCells
    303. Yuh CH, Li X, Davidson EH, Klein WH. Correct Expression of spec2a in the sea urchin embryo requires both Otx and other cis-regulatory elements. Dev Biol. 2001 Apr 15; 232(2):424-38. PMID: 11401403.
      Citations: 7     Fields:    Translation:AnimalsCells
    304. Klein WL, Krafft GA, Finch CE. Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum? Trends Neurosci. 2001 Apr; 24(4):219-24. PMID: 11250006.
      Citations: 313     Fields:    Translation:AnimalsCells
    305. Myer A, Olson EN, Klein WH. MyoD cannot compensate for the absence of myogenin during skeletal muscle differentiation in murine embryonic stem cells. Dev Biol. 2001 Jan 15; 229(2):340-50. PMID: 11203698.
      Citations: 27     Fields:    Translation:AnimalsCells
    306. Wang SW, Kim BS, Ding K, Wang H, Sun D, Johnson RL, Klein WH, Gan L. Requirement for math5 in the development of retinal ganglion cells. Genes Dev. 2001 Jan 01; 15(1):24-9. PMID: 11156601.
      Citations: 196     Fields:    Translation:AnimalsCells
    307. Chromy BA, Lambert MP, Klein WL. Increased Protein Tyrosine Phosphorylation in Apoptotic Neural Cell Death Due to Microtubule Perturbations. Neurotox Res. 2000 Dec; 2(4):357-372. PMID: 25242875.
      Citations:    Fields:    
    308. Longo VD, Viola KL, Klein WL, Finch CE. Reversible inactivation of superoxide-sensitive aconitase in Abeta1-42-treated neuronal cell lines. J Neurochem. 2000 Nov; 75(5):1977-85. PMID: 11032887.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    309. Klein W, Winkelmann D, Hahn M, Weber T, Marahiel MA. Molecular characterization of the transition state regulator AbrB from Bacillus stearothermophilus. Biochim Biophys Acta. 2000 Sep 07; 1493(1-2):82-90. PMID: 10978510.
      Citations:    Fields:    Translation:Cells
    310. Vivian JL, Olson EN, Klein WH. Thoracic skeletal defects in myogenin- and MRF4-deficient mice correlate with early defects in myotome and intercostal musculature. Dev Biol. 2000 Aug 01; 224(1):29-41. PMID: 10898959.
      Citations: 9     Fields:    Translation:Animals
    311. Wang SW, Gan L, Martin SE, Klein WH. Abnormal polarization and axon outgrowth in retinal ganglion cells lacking the POU-domain transcription factor Brn-3b. Mol Cell Neurosci. 2000 Aug; 16(2):141-56. PMID: 10924257.
      Citations: 34     Fields:    Translation:AnimalsCells
    312. Valdez MR, Richardson JA, Klein WH, Olson EN. Failure of Myf5 to support myogenic differentiation without myogenin, MyoD, and MRF4. Dev Biol. 2000 Mar 15; 219(2):287-98. PMID: 10694423.
      Citations: 38     Fields:    Translation:AnimalsCells
    313. Huang L, Li X, El-Hodiri HM, Dayal S, Wikramanayake AH, Klein WH. Involvement of Tcf/Lef in establishing cell types along the animal-vegetal axis of sea urchins. Dev Genes Evol. 2000 Feb; 210(2):73-81. PMID: 10664150.
      Citations: 5     Fields:    Translation:AnimalsCells
    314. Wagner DS, Gan L, Klein WH. Identification of a differentially expressed RNA helicase by gene trapping. Biochem Biophys Res Commun. 1999 Sep 07; 262(3):677-84. PMID: 10471385.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    315. Li X, Wikramanayake AH, Klein WH. Requirement of SpOtx in cell fate decisions in the sea urchin embryo and possible role as a mediator of beta-catenin signaling. Dev Biol. 1999 Aug 15; 212(2):425-39. PMID: 10433832.
      Citations: 9     Fields:    Translation:AnimalsCells
    316. Bladergroen BA, Bussière M, Klein W, Geelen MJ, Van Golde LM, Houweling M. Inhibition of phosphatidylcholine and phosphatidylethanolamine biosynthesis in rat-2 fibroblasts by cell-permeable ceramides. Eur J Biochem. 1999 Aug; 264(1):152-60. PMID: 10447683.
      Citations: 6     Fields:    Translation:AnimalsCells
    317. Vivian JL, Klein WH, Hasty P. Temporal, spatial and tissue-specific expression of a myogenin-lacZ transgene targeted to the Hprt locus in mice. Biotechniques. 1999 Jul; 27(1):154-62. PMID: 10407678.
      Citations: 8     Fields:    Translation:AnimalsCells
    318. Gan L, Wang SW, Huang Z, Klein WH. POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification. Dev Biol. 1999 Jun 15; 210(2):469-80. PMID: 10357904.
      Citations: 88     Fields:    Translation:HumansAnimalsCells
    319. Klein WH, Li X. Function and evolution of Otx proteins. Biochem Biophys Res Commun. 1999 May 10; 258(2):229-33. PMID: 10375352.
      Citations: 7     Fields:    Translation:AnimalsCells
    320. Vivian JL, Gan L, Olson EN, Klein WH. A hypomorphic myogenin allele reveals distinct myogenin expression levels required for viability, skeletal muscle development, and sternum formation. Dev Biol. 1999 Apr 01; 208(1):44-55. PMID: 10075840.
      Citations: 7     Fields:    Translation:AnimalsCells
    321. Olson EN, Klein WH. Muscle minus myoD. Dev Biol. 1998 Oct 15; 202(2):153-6. PMID: 9769168.
      Citations: 7     Fields:    Translation:AnimalsCells
    322. Wagner DS, Gan L, Klein WH. Expression of a gene trap reporter construct in a subset of cells in embryonic sites of hematopoiesis: evidence for alternative rRNA production in hematopoietic cells. Biochem Biophys Res Commun. 1998 Sep 29; 250(3):674-81. PMID: 9784405.
      Citations: 1     Fields:    Translation:AnimalsCells
    323. Wikramanayake AH, Huang L, Klein WH. beta-Catenin is essential for patterning the maternally specified animal-vegetal axis in the sea urchin embryo. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9343-8. PMID: 9689082.
      Citations: 60     Fields:    Translation:AnimalsCells
    324. Lin X, Gan L, Klein WH, Wells D. Expression and functional analysis of mouse EXT1, a homolog of the human multiple exostoses type 1 gene. Biochem Biophys Res Commun. 1998 Jul 30; 248(3):738-43. PMID: 9703997.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    325. Rawls A, Valdez MR, Zhang W, Richardson J, Klein WH, Olson EN. Overlapping functions of the myogenic bHLH genes MRF4 and MyoD revealed in double mutant mice. Development. 1998 Jul; 125(13):2349-58. PMID: 9609818.
      Citations: 37     Fields:    Translation:AnimalsCells
    326. Lambert MP, Barlow AK, Chromy BA, Edwards C, Freed R, Liosatos M, Morgan TE, Rozovsky I, Trommer B, Viola KL, Wals P, Zhang C, Finch CE, Krafft GA, Klein WL. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc Natl Acad Sci U S A. 1998 May 26; 95(11):6448-53. PMID: 9600986.
      Citations: 1134     Fields:    Translation:AnimalsCells
    327. Berg MM, Krafft GA, Klein WL. Rapid impact of beta-amyloid on paxillin in a neural cell line. J Neurosci Res. 1997 Dec 15; 50(6):979-89. PMID: 9452012.
      Citations: 8     Fields:    Translation:AnimalsCells
    328. Xiang M, Gan L, Li D, Chen ZY, Zhou L, O'Malley BW, Klein W, Nathans J. Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9445-50. PMID: 9256502.
      Citations: 95     Fields:    Translation:AnimalsCells
    329. Li X, Chuang CK, Mao CA, Angerer LM, Klein WH. Two Otx proteins generated from multiple transcripts of a single gene in Strongylocentrotus purpuratus. Dev Biol. 1997 Jul 15; 187(2):253-66. PMID: 9242422.
      Citations: 10     Fields:    Translation:AnimalsCells
    330. Myer A, Wagner DS, Vivian JL, Olson EN, Klein WH. Wild-type myoblasts rescue the ability of myogenin-null myoblasts to fuse in vivo. Dev Biol. 1997 May 15; 185(2):127-38. PMID: 9187078.
      Citations: 4     Fields:    Translation:AnimalsCells
    331. Klein WM. Objective standards are not enough: affective, self-evaluative, and behavioral responses to social comparison information. J Pers Soc Psychol. 1997 Apr; 72(4):763-74. PMID: 9108694.
      Citations: 28     Fields:    Translation:Humans
    332. Xiang M, Gan L, Li D, Zhou L, Chen ZY, Wagner D, O'Malley BW, Klein W, Nathans J. Role of the Brn-3 family of POU-domain genes in the development of the auditory/vestibular, somatosensory, and visual systems. Cold Spring Harb Symp Quant Biol. 1997; 62:325-36. PMID: 9598366.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    333. Wikramanayake AH, Klein WH. Multiple signaling events specify ectoderm and pattern the oral-aboral axis in the sea urchin embryo. Development. 1997 Jan; 124(1):13-20. PMID: 9006063.
      Citations: 9     Fields:    Translation:AnimalsCells
    334. Wang W, Wikramanayake AH, Gonzalez-Rimbau M, Vlahou A, Flytzanis CN, Klein WH. Very early and transient vegetal-plate expression of SpKrox1, a Krüppel/Krox gene from Stronglyocentrotus purpuratus. Mech Dev. 1996 Dec; 60(2):185-95. PMID: 9025071.
      Citations: 6     Fields:    Translation:AnimalsCells
    335. Stevens GR, Zhang C, Berg MM, Lambert MP, Barber K, Cantallops I, Routtenberg A, Klein WL. CNS neuronal focal adhesion kinase forms clusters that co-localize with vinculin. J Neurosci Res. 1996 Nov 15; 46(4):445-55. PMID: 8950704.
      Citations: 6     Fields:    Translation:AnimalsCells
    336. Horlacher R, Uhland K, Klein W, Ehrmann M, Boos W. Characterization of a cytoplasmic trehalase of Escherichia coli. J Bacteriol. 1996 Nov; 178(21):6250-7. PMID: 8892826.
      Citations: 17     Fields:    Translation:Cells
    337. Xiang M, Gan L, Zhou L, Klein WH, Nathans J. Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11950-5. PMID: 8876243.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    338. Brennan TJ, Olson EN, Klein WH, Winslow JW. Extensive motor neuron survival in the absence of secondary skeletal muscle fiber formation. J Neurosci Res. 1996 Jul 01; 45(1):57-68. PMID: 8811512.
      Citations: 2     Fields:    Translation:AnimalsCells
    339. Zhang C, Qiu HE, Krafft GA, Klein WL. A beta peptide enhances focal adhesion kinase/Fyn association in a rat CNS nerve cell line. Neurosci Lett. 1996 Jun 28; 211(3):187-90. PMID: 8817572.
      Citations: 9     Fields:    Translation:AnimalsCells
    340. Zhang C, Qiu HE, Krafft GA, Klein WL. Protein kinase C and F-actin are essential for stimulation of neuronal FAK tyrosine phosphorylation by G-proteins and amyloid beta protein. FEBS Lett. 1996 May 20; 386(2-3):185-8. PMID: 8647278.
      Citations: 4     Fields:    Translation:AnimalsCells
    341. Mao CA, Wikramanayake AH, Gan L, Chuang CK, Summers RG, Klein WH. Altering cell fates in sea urchin embryos by overexpressing SpOtx, an orthodenticle-related protein. Development. 1996 May; 122(5):1489-98. PMID: 8625836.
      Citations: 5     Fields:    Translation:AnimalsCells
    342. Gan L, Xiang M, Zhou L, Wagner DS, Klein WH, Nathans J. POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells. Proc Natl Acad Sci U S A. 1996 Apr 30; 93(9):3920-5. PMID: 8632990.
      Citations: 130     Fields:    Translation:AnimalsCells
    343. Cheng JQ, Ruggeri B, Klein WM, Sonoda G, Altomare DA, Watson DK, Testa JR. Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc Natl Acad Sci U S A. 1996 Apr 16; 93(8):3636-41. PMID: 8622988.
      Citations: 191     Fields:    Translation:HumansAnimalsCells
    344. Barber K, Mala RR, Lambert MP, Qiu R, MacDonald RC, Klein WL. Delivery of membrane-impermeant fluorescent probes into living neural cell populations by lipotransfer. Neurosci Lett. 1996 Mar 22; 207(1):17-20. PMID: 8710199.
      Citations: 6     Fields:    Translation:AnimalsCells
    345. Bodovitz S, Klein WL. Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J Biol Chem. 1996 Feb 23; 271(8):4436-40. PMID: 8626795.
      Citations: 117     Fields:    Translation:HumansCells
    346. Wang W, Klein WH. A G/C-rich DNA-regulatory element controls positive expression of the sea urchin Lytechinus pictus aboral ectoderm-specific LpS1 gene. DNA Cell Biol. 1996 Feb; 15(2):133-45. PMID: 8634141.
      Citations: 1     Fields:    Translation:AnimalsCells
    347. Chuang CK, Wikramanayake AH, Mao CA, Li X, Klein WH. Transient appearance of Strongylocentrotus purpuratus Otx in micromere nuclei: cytoplasmic retention of SpOtx possibly mediated through an alpha-actinin interaction. Dev Genet. 1996; 19(3):231-7. PMID: 8952065.
      Citations: 8     Fields:    Translation:AnimalsCells
    348. Rawls A, Morris JH, Rudnicki M, Braun T, Arnold HH, Klein WH, Olson EN. Myogenin's functions do not overlap with those of MyoD or Myf-5 during mouse embryogenesis. Dev Biol. 1995 Nov; 172(1):37-50. PMID: 7589813.
      Citations: 40     Fields:    Translation:AnimalsCells
    349. Klein W, Horlacher R, Boos W. Molecular analysis of treB encoding the Escherichia coli enzyme II specific for trehalose. J Bacteriol. 1995 Jul; 177(14):4043-52. PMID: 7608078.
      Citations: 18     Fields:    Translation:Cells
    350. Lambert MP, Sabo S, Zhang C, Enam SA, Klein WL. Constitutive Alzheimer's-type tau epitopes in a neuritogenic rat CNS cell line. Neurobiol Aging. 1995 Jul-Aug; 16(4):583-9. PMID: 8544909.
      Citations: 7     Fields:    Translation:AnimalsCells
    351. Martin H, Lambert MP, Barber K, Hinton S, Klein WL. Alzheimer's-associated phospho-tau epitope in human neuroblastoma cell cultures: up-regulation by fibronectin and laminin. Neuroscience. 1995 Jun; 66(4):769-79. PMID: 7651608.
      Citations: 1     Fields:    Translation:HumansCells
    352. Wikramanayake AH, Brandhorst BP, Klein WH. Autonomous and non-autonomous differentiation of ectoderm in different sea urchin species. Development. 1995 May; 121(5):1497-505. PMID: 7789279.
      Citations: 8     Fields:    Translation:Animals
    353. Barber K, Enam SA, Bodovitz S, Falduto M, Frail D, Klein WL. Particulate forms of APP in the extracellular milieu of cultured cells. Exp Neurol. 1995 Mar; 132(1):42-53. PMID: 7720825.
      Citations: 1     Fields:    Translation:AnimalsCells
    354. Gan L, Mao CA, Wikramanayake A, Angerer LM, Angerer RC, Klein WH. An orthodenticle-related protein from Strongylocentrotus purpuratus. Dev Biol. 1995 Feb; 167(2):517-28. PMID: 7875376.
      Citations: 6     Fields:    Translation:AnimalsCells
    355. Venuti JM, Morris JH, Vivian JL, Olson EN, Klein WH. Myogenin is required for late but not early aspects of myogenesis during mouse development. J Cell Biol. 1995 Feb; 128(4):563-76. PMID: 7532173.
      Citations: 69     Fields:    Translation:AnimalsCells
    356. Cheng TC, Tseng BS, Merlie JP, Klein WH, Olson EN. Activation of the myogenin promoter during mouse embryogenesis in the absence of positive autoregulation. Proc Natl Acad Sci U S A. 1995 Jan 17; 92(2):561-5. PMID: 7831329.
      Citations: 9     Fields:    Translation:AnimalsCells
    357. Sabo S, Lambert MP, Kessey K, Wade W, Krafft G, Klein WL. Interaction of beta-amyloid peptides with integrins in a human nerve cell line. Neurosci Lett. 1995 Jan 16; 184(1):25-8. PMID: 7739799.
      Citations: 11     Fields:    Translation:HumansCells
    358. Bodovitz S, Falduto MT, Frail DE, Klein WL. Iron levels modulate alpha-secretase cleavage of amyloid precursor protein. J Neurochem. 1995 Jan; 64(1):307-15. PMID: 7798927.
      Citations: 26     Fields:    Translation:AnimalsCells
    359. Ladror US, Kohnken RE, Wang GT, Manelli AM, Frail DE, Klein WL, Holzman TF, Krafft GA. Evidence against a role for the Kunitz domain in amyloidogenic and secretory processing of the amyloid precursor protein. J Neurochem. 1994 Dec; 63(6):2225-30. PMID: 7964742.
      Citations:    Fields:    Translation:HumansCells
    360. Lambert MP, Stevens G, Sabo S, Barber K, Wang G, Wade W, Krafft G, Snyder S, Holzman TF, Klein WL. Beta/A4-evoked degeneration of differentiated SH-SY5Y human neuroblastoma cells. J Neurosci Res. 1994 Nov 01; 39(4):377-85. PMID: 7533843.
      Citations: 19     Fields:    Translation:HumansCells
    361. Zhang C, Lambert MP, Bunch C, Barber K, Wade WS, Krafft GA, Klein WL. Focal adhesion kinase expressed by nerve cell lines shows increased tyrosine phosphorylation in response to Alzheimer's A beta peptide. J Biol Chem. 1994 Oct 14; 269(41):25247-50. PMID: 7929215.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    362. Wang GT, Ladror US, Holzman TF, Klein WL, Krafft GA. Cleavage of fluorogenic substrates for APP-processing proteases by human brain extracts. Ca(2+)-substrate interaction is responsible for Ca2+ stimulation of the neural protease activity. Mol Chem Neuropathol. 1994 Oct-Dec; 23(2-3):191-9. PMID: 7702708.
      Citations: 2     Fields:    Translation:HumansCells
    363. Mao CA, Gan L, Klein WH. Multiple Otx binding sites required for expression of the Strongylocentrotus purpuratus Spec2a gene. Dev Biol. 1994 Sep; 165(1):229-42. PMID: 8088441.
      Citations: 8     Fields:    Translation:AnimalsCells
    364. Ladror US, Wang GT, Klein WL, Holzman TF, Krafft GA. Potential beta PP-processing proteinase activities from Alzheimer's and control brain tissues. J Protein Chem. 1994 May; 13(4):357-66. PMID: 7986341.
      Citations:    Fields:    Translation:HumansCells
    365. Pope WB, Lambert MP, Leypold B, Seupaul R, Sletten L, Krafft G, Klein WL. Microtubule-associated protein tau is hyperphosphorylated during mitosis in the human neuroblastoma cell line SH-SY5Y. Exp Neurol. 1994 Apr; 126(2):185-94. PMID: 7925819.
      Citations: 27     Fields:    Translation:HumansCells
    366. Olson EN, Klein WH. bHLH factors in muscle development: dead lines and commitments, what to leave in and what to leave out. Genes Dev. 1994 Jan; 8(1):1-8. PMID: 8288123.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    367. Hasty P, Bradley A, Morris JH, Edmondson DG, Venuti JM, Olson EN, Klein WH. Muscle deficiency and neonatal death in mice with a targeted mutation in the myogenin gene. Nature. 1993 Aug 05; 364(6437):501-6. PMID: 8393145.
      Citations: 342     Fields:    Translation:Animals
    368. Skorupa AF, Klein WL. Developmentally regulated secreted factors control expression of muscarinic receptor subtypes in embryonic chick retina. J Neurochem. 1993 Jun; 60(6):2087-97. PMID: 8492118.
      Citations:    Fields:    Translation:AnimalsCells
    369. Gan L, Klein WH. A positive cis-regulatory element with a bicoid target site lies within the sea urchin Spec2a enhancer. Dev Biol. 1993 May; 157(1):119-32. PMID: 8097732.
      Citations: 3     Fields:    Translation:AnimalsCells
    370. Venuti JM, Gan L, Kozlowski MT, Klein WH. Developmental potential of muscle cell progenitors and the myogenic factor SUM-1 in the sea urchin embryo. Mech Dev. 1993 Apr; 41(1):3-14. PMID: 8389581.
      Citations: 5     Fields:    Translation:AnimalsCells
    371. Pope W, Enam SA, Bawa N, Miller BE, Ghanbari HA, Klein WL. Phosphorylated tau epitope of Alzheimer's disease is coupled to axon development in the avian central nervous system. Exp Neurol. 1993 Mar; 120(1):106-13. PMID: 7682967.
      Citations: 6     Fields:    Translation:AnimalsCells
    372. Klein W, Boos W. Induction of the lambda receptor is essential for effective uptake of trehalose in Escherichia coli. J Bacteriol. 1993 Mar; 175(6):1682-6. PMID: 8449875.
      Citations: 11     Fields:    Translation:Cells
    373. Tsui HC, Pope WB, Kim CS, Klein WL. Transient expression of adheron molecules during chick retinal development. J Neurobiol. 1992 Aug; 23(6):720-38. PMID: 1431842.
      Citations: 1     Fields:    Translation:AnimalsCells
    374. Martinic M, Lambert MP, Hua S, Klein WL. Cholinergic differentiation in neurogenic basal forebrain cultures. J Neurobiol. 1992 Apr; 23(3):252-69. PMID: 1624933.
      Citations:    Fields:    Translation:AnimalsCells
    375. Sirito M, Walker S, Lin Q, Kozlowski MT, Klein WH, Sawadogo M. Members of the USF family of helix-loop-helix proteins bind DNA as homo- as well as heterodimers. Gene Expr. 1992; 2(3):231-40. PMID: 1450663.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    376. Xiang M, Lu SY, Musso M, Karsenty G, Klein WH. A G-string positive cis-regulatory element in the LpS1 promoter binds two distinct nuclear factors distributed non-uniformly in Lytechinus pictus embryos. Development. 1991 Dec; 113(4):1345-55. PMID: 1811948.
      Citations: 8     Fields:    Translation:AnimalsCells
    377. Kozlowski MT, Gan L, Venuti JM, Sawadogo M, Klein WH. Sea urchin USF: a helix-loop-helix protein active in embryonic ectoderm cells. Dev Biol. 1991 Dec; 148(2):625-30. PMID: 1743406.
      Citations: 12     Fields:    Translation:AnimalsCells
    378. Hengge-Aronis R, Klein W, Lange R, Rimmele M, Boos W. Trehalose synthesis genes are controlled by the putative sigma factor encoded by rpoS and are involved in stationary-phase thermotolerance in Escherichia coli. J Bacteriol. 1991 Dec; 173(24):7918-24. PMID: 1744047.
      Citations: 137     Fields:    Translation:Cells
    379. Fonseca MI, Aguilar JS, Skorupa AF, Klein WL. Cellular mapping of m2 muscarinic receptors in rat olfactory bulb using an antiserum raised against a cytoplasmic loop peptide. Brain Res. 1991 Nov 01; 563(1-2):163-70. PMID: 1786528.
      Citations: 2     Fields:    Translation:AnimalsCells
    380. Venuti JM, Goldberg L, Chakraborty T, Olson EN, Klein WH. A myogenic factor from sea urchin embryos capable of programming muscle differentiation in mammalian cells. Proc Natl Acad Sci U S A. 1991 Jul 15; 88(14):6219-23. PMID: 2068103.
      Citations: 16     Fields:    Translation:AnimalsCells
    381. Xiang MQ, Ge T, Tomlinson CR, Klein WH. Structure and promoter activity of the LpS1 genes of Lytechinus pictus. Duplicated exons account for LpS1 proteins with eight calcium binding domains. J Biol Chem. 1991 Jun 05; 266(16):10524-33. PMID: 2037596.
      Citations: 5     Fields:    Translation:AnimalsCells
    382. Klein W, Ehmann U, Boos W. The repression of trehalose transport and metabolism in Escherichia coli by high osmolarity is mediated by trehalose-6-phosphate phosphatase. Res Microbiol. 1991 May; 142(4):359-71. PMID: 1651549.
      Citations: 12     Fields:    Translation:Cells
    383. van der Pal RH, Klein W, van Golde LM, Lopes-Cardozo M. Developmental profiles of arylsulfatases A and B in rat cerebral cortex and spinal cord. Biochim Biophys Acta. 1991 Feb 05; 1081(3):315-20. PMID: 1671824.
      Citations: 3     Fields:    Translation:Animals
    384. Pevny L, Simon MC, Robertson E, Klein WH, Tsai SF, D'Agati V, Orkin SH, Costantini F. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature. 1991 Jan 17; 349(6306):257-60. PMID: 1987478.
      Citations: 392     Fields:    Translation:AnimalsCells
    385. Gan L, Wessel GM, Klein WH. Regulatory elements from the related spec genes of Strongylocentrotus purpuratus yield different spatial patterns with a lacZ reporter gene. Dev Biol. 1990 Dec; 142(2):346-59. PMID: 1701736.
      Citations: 8     Fields:    Translation:AnimalsCells
    386. Tomlinson CR, Kozlowski MT, Klein WH. Ectoderm nuclei from sea urchin embryos contain a Spec-DNA binding protein similar to the vertebrate transcription factor USF. Development. 1990 Sep; 110(1):259-72. PMID: 2081463.
      Citations: 3     Fields:    Translation:AnimalsCells
    387. Wessel GM, Zhang W, Klein WH. Myosin heavy chain accumulates in dissimilar cell types of the macromere lineage in the sea urchin embryo. Dev Biol. 1990 Aug; 140(2):447-54. PMID: 1695586.
      Citations: 5     Fields:    Translation:AnimalsCells
    388. Boos W, Ehmann U, Forkl H, Klein W, Rimmele M, Postma P. Trehalose transport and metabolism in Escherichia coli. J Bacteriol. 1990 Jun; 172(6):3450-61. PMID: 2160944.
      Citations: 52     Fields:    Translation:Cells
    389. Gan L, Zhang W, Klein WH. Repetitive DNA sequences linked to the sea urchin spec genes contain transcriptional enhancer-like elements. Dev Biol. 1990 May; 139(1):186-96. PMID: 2328835.
      Citations: 10     Fields:    Translation:AnimalsCells
    390. Tomlinson CR, Klein WH. Temporal and spatial transcriptional regulation of the aboral ectoderm-specific Spec genes during sea urchin embryogenesis. Mol Reprod Dev. 1990 Apr; 25(4):328-38. PMID: 2328125.
      Citations: 6     Fields:    Translation:AnimalsCells
    391. van der Pal RH, Klein W, van Golde LM, Lopes-Cardozo M. Galactosylceramide sulfotransferase, arylsulfatase A and cerebroside sulfatase activity in different regions of developing rat brain. Biochim Biophys Acta. 1990 Mar 12; 1043(1):91-6. PMID: 1968763.
      Citations: 3     Fields:    Translation:AnimalsCells
    392. DeMello FG, DeMello MC, Hudson R, Klein WL. Selective expression of factors preventing cholinergic dedifferentiation. J Neurochem. 1990 Mar; 54(3):886-92. PMID: 2406375.
      Citations: 3     Fields:    Translation:AnimalsCells
    393. Tsui HC, Klein WL. Biochemical differentiation of nascent neurite junctions: unilateral localization of adheron components. Brain Res Dev Brain Res. 1990 Feb 01; 51(2):205-16. PMID: 2323029.
      Citations:    Fields:    Translation:AnimalsCells
    394. Lankford KL, Klein WL. Ultrastructure of individual neurons isolated from avian retina: occurrence of microtubule loops in dendrites. Brain Res Dev Brain Res. 1990 Feb 01; 51(2):217-24. PMID: 2323030.
      Citations: 4     Fields:    Translation:AnimalsCells
    395. Eldon ED, Montpetit IC, Nguyen T, Decker G, Valdizan MC, Klein WH, Brandhorst BP. Localization of the sea urchin Spec3 protein to cilia and Golgi complexes of embryonic ectoderm cells. Genes Dev. 1990 Jan; 4(1):111-22. PMID: 2407617.
      Citations: 1     Fields:    Translation:AnimalsCells
    396. Wessel GM, Goldberg L, Lennarz WJ, Klein WH. Gastrulation in the sea urchin is accompanied by the accumulation of an endoderm-specific mRNA. Dev Biol. 1989 Dec; 136(2):526-36. PMID: 2583374.
      Citations: 4     Fields:    Translation:AnimalsCells
    397. Klein WL, Sullivan J, Skorupa A, Aguilar JS. Plasticity of neuronal receptors. FASEB J. 1989 Aug; 3(10):2132-40. PMID: 2546848.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    398. Wessel GM, Zhang W, Tomlinson CR, Lennarz WJ, Klein WH. Transcription of the Spec 1-like gene of Lytechinus is selectively inhibited in response to disruption of the extracellular matrix. Development. 1989 Jun; 106(2):355-65. PMID: 2591320.
      Citations: 5     Fields:    Translation:AnimalsCells
    399. Xiang MQ, Bédard PA, Wessel G, Filion M, Brandhorst BP, Klein WH. Tandem duplication and divergence of a sea urchin protein belonging to the troponin C superfamily. J Biol Chem. 1988 Nov 15; 263(32):17173-80. PMID: 3182842.
      Citations: 6     Fields:    Translation:AnimalsCells
    400. James WM, Klein WL. Localization of acetylcholine receptors on isolated CNS neurons: cellular and subcellular differentiation. J Neurosci. 1988 Nov; 8(11):4225-38. PMID: 3183721.
      Citations:    Fields:    Translation:AnimalsCells
    401. Hardin PE, Angerer LM, Hardin SH, Angerer RC, Klein WH. Spec2 genes of Strongylocentrotus purpuratus. Structure and differential expression in embryonic aboral ectoderm cells. J Mol Biol. 1988 Aug 05; 202(3):417-31. PMID: 3172223.
      Citations: 11     Fields:    Translation:AnimalsCells
    402. Lankford KL, DeMello FG, Klein WL. D1-type dopamine receptors inhibit growth cone motility in cultured retina neurons: evidence that neurotransmitters act as morphogenic growth regulators in the developing central nervous system. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4567-71. PMID: 3380807.
      Citations: 16     Fields:    Translation:AnimalsCells
    403. Tsui HC, Schubert D, Klein WL. Molecular basis of growth cone adhesion: anchoring of adheron-containing filaments at adhesive loci. J Cell Biol. 1988 Jun; 106(6):2095-108. PMID: 3384855.
      Citations:    Fields:    Translation:AnimalsCells
    404. Lambert MP, Megerian T, Garden G, Klein WL. Soluble proteins from rat olfactory bulb promote the survival and differentiation of cultured basal forebrain neurons. Brain Res. 1988 Jun 01; 469(1-2):263-76. PMID: 3401803.
      Citations:    Fields:    Translation:AnimalsCells
    405. Warringa RA, van Berlo MF, Klein W, Lopes-Cardozo M. Cellular location of glutamine synthetase and lactate dehydrogenase in oligodendrocyte-enriched cultures from rat brain. J Neurochem. 1988 May; 50(5):1461-8. PMID: 2896229.
      Citations: 8     Fields:    Translation:AnimalsCells
    406. Cho NJ, Klein WL. Muscarinic acetylcholine receptors from avian retina and heart undergo different patterns of molecular maturation. J Neurochem. 1988 May; 50(5):1403-11. PMID: 3283293.
      Citations: 2     Fields:    Translation:AnimalsCells
    407. Lankford KL, DeMello FG, Klein WL. D1-type dopamine receptors inhibit growth cone motility in cultured retina neurons: evidence that neurotransmitters act as morphogenic growth regulators in the developing central nervous system. Proc Natl Acad Sci U S A. 1988 Apr; 85(8):2839-43. PMID: 3357895.
      Citations: 10     Fields:    Translation:AnimalsCells
    408. de Mello MC, Klein WL, de Mello FG. L-glutamate evoked release of GABA from cultured avian retina cells does not require glutamate receptor activation. Brain Res. 1988 Mar 08; 443(1-2):166-72. PMID: 2896053.
      Citations: 6     Fields:    Translation:AnimalsCells
    409. Eldon ED, Angerer LM, Angerer RC, Klein WH. Spec3: embryonic expression of a sea urchin gene whose product is involved in ectodermal ciliogenesis. Genes Dev. 1987 Dec; 1(10):1280-92. PMID: 2828169.
      Citations: 2     Fields:    Translation:AnimalsCells
    410. Hardin SH, Keast MJ, Hardin PE, Klein WH. Use of consensus oligonucleotides for detecting and isolating nucleic acids encoding calcium binding domains of the troponin C superfamily. Biochemistry. 1987 Jun 16; 26(12):3518-23. PMID: 3651394.
      Citations: 2     Fields:    Translation:AnimalsCells
    411. Lankford K, De Mello FG, Klein WL. A transient embryonic dopamine receptor inhibits growth cone motility and neurite outgrowth in a subset of avian retina neurons. Neurosci Lett. 1987 Mar 31; 75(2):169-74. PMID: 2952906.
      Citations: 10     Fields:    Translation:AnimalsCells
    412. Hardin PE, Klein WH. Unusual sequence conservation in the 5' and 3' untranslated regions of the sea urchin spec mRNAs. J Mol Evol. 1987; 25(2):126-33. PMID: 3116272.
      Citations: 3     Fields:    Translation:AnimalsCells
    413. Large TH, Lambert MP, Cohen NM, Klein WL. Autonomous control of phosphatidylinositol turnover by histamine and acetylcholine receptors in the N1E-115 neuron-like cell line. Neurosci Lett. 1986 May 06; 66(1):31-8. PMID: 3714112.
      Citations: 1     Fields:    Translation:Cells
    414. Large TH, Lambert MP, Gremillion MA, Klein WL. Parallel postnatal development of choline acetyltransferase activity and muscarinic acetylcholine receptors in the rat olfactory bulb. J Neurochem. 1986 Mar; 46(3):671-80. PMID: 3754001.
      Citations: 3     Fields:    Translation:AnimalsCells
    415. Floyd EE, Gong ZY, Brandhorst BP, Klein WH. Calmodulin gene expression during sea urchin development: persistence of a prevalent maternal protein. Dev Biol. 1986 Feb; 113(2):501-11. PMID: 3753945.
      Citations: 6     Fields:    Translation:AnimalsCells
    416. Rauh JJ, Lambert MP, Cho NJ, Chin H, Klein WL. Glycoprotein properties of muscarinic acetylcholine receptors from bovine cerebral cortex. J Neurochem. 1986 Jan; 46(1):23-32. PMID: 3940285.
      Citations: 1     Fields:    Translation:Animals
    417. Large TH, Rauh JJ, De Mello FG, Klein WL. Two molecular weight forms of muscarinic acetylcholine receptors in the avian central nervous system: switch in predominant form during differentiation of synapses. Proc Natl Acad Sci U S A. 1985 Dec; 82(24):8785-9. PMID: 3866251.
      Citations: 3     Fields:    Translation:AnimalsCells
    418. Tsui HC, Lankford KL, Klein WL. Differentiation of neuronal growth cones: specialization of filopodial tips for adhesive interactions. Proc Natl Acad Sci U S A. 1985 Dec; 82(23):8256-60. PMID: 3865227.
      Citations: 14     Fields:    Translation:AnimalsCells
    419. Hardin SH, Carpenter CD, Hardin PE, Bruskin AM, Klein WH. Structure of the Spec1 gene encoding a major calcium-binding protein in the embryonic ectoderm of the sea urchin, Strongylocentrotus purpuratus. J Mol Biol. 1985 Nov 20; 186(2):243-55. PMID: 2935638.
      Citations: 18     Fields:    Translation:AnimalsCells
    420. Lay JP, Schauerte W, Peichl L, Klein W, Korte F. Influence of benzene on the phytoplankton and on Daphnia pulex in compartments of an experimental pond. Ecotoxicol Environ Saf. 1985 Oct; 10(2):218-27. PMID: 4085381.
      Citations:    Fields:    Translation:Animals
    421. Large TH, Cho NJ, De Mello FG, Klein WL. Molecular alteration of a muscarinic acetylcholine receptor system during synaptogenesis. J Biol Chem. 1985 Jul 25; 260(15):8873-81. PMID: 2991223.
      Citations: 3     Fields:    Translation:AnimalsCells
    422. Lay JP, Schauerte W, Müller A, Klein W, Korte F. Long-term effects of 1,2,4-trichlorobenzene on freshwater plankton in an outdoor-model-ecosystem. Bull Environ Contam Toxicol. 1985 May; 34(5):761-9. PMID: 4005457.
      Citations:    Fields:    
    423. Scheunert I, Topp E, Schmitzer J, Klein W, Korte F. Formation and fate of bound residues of [14C]benzene and [14C]chlorobenzenes in soil and plants. Ecotoxicol Environ Saf. 1985 Apr; 9(2):159-70. PMID: 3987596.
      Citations: 1     Fields:    Translation:Animals
    424. James WM, Klein WL. alpha-Bungarotoxin receptors on neurons isolated from turtle retina: molecular heterogeneity of bipolar cells. J Neurosci. 1985 Feb; 5(2):352-61. PMID: 3973670.
      Citations: 1     Fields:    Translation:AnimalsCells
    425. Lopes-Cardozo M, Klein W. Contribution of acetoacetate to the synthesis of cholesterol and fatty acids in regions of developing rat brain in vivo. Neurochem Int. 1985; 7(4):647-53. PMID: 20492971.
      Citations: 1     Fields:    
    426. Tsui HT, Lankford KL, Ris H, Klein WL. Novel organization of microtubules in cultured central nervous system neurons: formation of hairpin loops at ends of maturing neurites. J Neurosci. 1984 Dec; 4(12):3002-13. PMID: 6502218.
      Citations: 17     Fields:    Translation:AnimalsCells
    427. Muesing M, Carpenter CD, Klein WH, Polisky B. High-level expression in Escherichia coli of calcium-binding domains of an embryonic sea urchin protein. Gene. 1984 Nov; 31(1-3):155-64. PMID: 6098520.
      Citations: 3     Fields:    Translation:AnimalsCells
    428. Carpenter CD, Bruskin AM, Hardin PE, Keast MJ, Anstrom J, Tyner AL, Brandhorst BP, Klein WH. Novel proteins belonging to the troponin C superfamily are encoded by a set of mRNAs in sea urchin embryos. Cell. 1984 Mar; 36(3):663-71. PMID: 6697391.
      Citations: 10     Fields:    Translation:Animals
    429. Ventura AL, Klein WL, de Mello FG. Differential ontogenesis of D1 and D2 dopaminergic receptors in the chick embryo retina. Brain Res. 1984 Feb; 314(2):217-23. PMID: 6200189.
      Citations: 5     Fields:    Translation:AnimalsCells
    430. Lopes-Cardozo M, Klein W. Ketone-body utilization and lipid synthesis by developing rat brain-a comparison between in vivo and in vitro experiments. Neurochem Int. 1984; 6(4):459-66. PMID: 20488069.
      Citations: 3     Fields:    
    431. Tsui HC, Ris H, Klein WL. Ultrastructural networks in growth cones and neurites of cultured central nervous system neurons. Proc Natl Acad Sci U S A. 1983 Sep; 80(18):5779-83. PMID: 6577454.
      Citations: 6     Fields:    Translation:AnimalsCells
    432. Scheunert I, Vockel D, Schmitzer J, Viswanathan R, Klein W, Korte F. Fate of chemicals in plant-soil systems: comparison of laboratory test data with results of open air long-term experiments. Ecotoxicol Environ Saf. 1983 Aug; 7(4):390-9. PMID: 6617565.
      Citations:    Fields:    Translation:AnimalsCells
    433. Lay JP, Klein W, Korte F. Elimination- and biodistribution studies of [14C]dodecylbenzene sulfonate in rats, following low dosing in the daily diet and a single i.p. administration. Toxicol Lett. 1983 Jun; 17(1-2):187-92. PMID: 6623504.
      Citations: 1     Fields:    Translation:Animals
    434. Lynn DA, Angerer LM, Bruskin AM, Klein WH, Angerer RC. Localization of a family of MRNAS in a single cell type and its precursors in sea urchin embryos. Proc Natl Acad Sci U S A. 1983 May; 80(9):2656-60. PMID: 6573676.
      Citations: 16     Fields:    Translation:AnimalsCells
    435. Forney JD, Epstein LM, Preer LB, Rudman BM, Widmayer DJ, Klein WH, Preer JR. Structure and expression of genes for surface proteins in Paramecium. Mol Cell Biol. 1983 Mar; 3(3):466-74. PMID: 6188948.
      Citations: 30     Fields:    Translation:AnimalsCells
    436. Siman RG, Klein WL. Differential regulation of muscarinic and nicotinic receptors by cholinergic stimulation in cultured avian retina cells. Brain Res. 1983 Feb 28; 262(1):99-108. PMID: 6831232.
      Citations: 3     Fields:    Translation:AnimalsCells
    437. Culotti JG, Klein WL. Occurrence of muscarinic acetylcholine receptors in wild type and cholinergic mutants of Caenorhabditis elegans. J Neurosci. 1983 Feb; 3(2):359-68. PMID: 6822867.
      Citations: 3     Fields:    Translation:AnimalsCells
    438. Cohen NM, Schmidt DM, McGlennen RC, Klein WL. Receptor-mediated increases in phosphatidylinositol turnover in neuron-like cell lines. J Neurochem. 1983 Feb; 40(2):547-54. PMID: 6822837.
      Citations: 4     Fields:    Translation:AnimalsCells
    439. James WM, Cheatham MA, Klein WL. Muscarinic acetylcholine receptor binding in the guinea pig cochlea. Hear Res. 1983 Jan; 9(1):113-21. PMID: 6826463.
      Citations: 2     Fields:    Translation:Animals
    440. Carpenter CD, Bruskin AM, Spain LM, Eldon ED, Klein WH. The 3' untranslated regions of two related mRNAs contain an element highly repeated in the sea urchin genome. Nucleic Acids Res. 1982 Dec 11; 10(23):7829-42. PMID: 6296792.
      Citations: 7     Fields:    Translation:AnimalsCells
    441. Schauerte W, Lay JP, Klein W, Korte F. Long-term fate of organochlorine xenobiotics in aquatic ecosystems. Distribution, residual behavior, and metabolism of hexachlorobenzene, pentachloronitrobenzene, and 4-chloroaniline in small experimental ponds. Ecotoxicol Environ Saf. 1982 Dec; 6(6):560-9. PMID: 7169047.
      Citations: 5     Fields:    Translation:AnimalsCells
    442. James WL, Klein WL. Autoradiography of dendritic acetylcholine receptors: a method for study of isolated neurons of the adult central nervous system in the turtle. Neurosci Lett. 1982 Sep 20; 32(1):5-10. PMID: 7145225.
      Citations:    Fields:    Translation:AnimalsCells
    443. de Mello MC, Ventura AL, Paes de Carvalho R, Klein WL, de Mello FG. Regulation of dopamine- and adenosine-dependent adenylate cyclase systems of chicken embryo retina cells in culture. Proc Natl Acad Sci U S A. 1982 Sep; 79(18):5708-12. PMID: 6291061.
      Citations: 12     Fields:    Translation:AnimalsCells
    444. Korte F, Klein W. Degradation of benzene in the environment. Ecotoxicol Environ Saf. 1982 Aug; 6(4):311-27. PMID: 7117183.
      Citations:    Fields:    Translation:HumansPHPublic Health
    445. Bruskin AM, Bedard PA, Tyner AL, Showman RM, Brandhorst BP, Klein WH. A family of proteins accumulating in ectoderm of sea urchin embryos specified by two related cDNA clones. Dev Biol. 1982 Jun; 91(2):317-24. PMID: 6284573.
      Citations: 3     Fields:    Translation:AnimalsCells
    446. Carpenter CD, Klein WH. A gradient of poly(A)+ RNA sequences in Xenopus laevis eggs and embryos. Dev Biol. 1982 May; 91(1):43-9. PMID: 6896500.
      Citations: 3     Fields:    Translation:AnimalsCells
    447. Freitag D, Geyer H, Kraus A, Viswanathan R, Kotzias D, Attar A, Klein W, Korte F. Ecotoxicological profile analysis. VII. Screening chemicals for their environmental behavior by comparative evaluation. Ecotoxicol Environ Saf. 1982 Feb; 6(1):60-81. PMID: 6802631.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    448. Siman RG, Klein WL. Specificity of muscarinic acetylcholine receptor regulation by receptor activity. J Neurochem. 1981 Nov; 37(5):1099-108. PMID: 7299390.
      Citations: 1     Fields:    Translation:AnimalsCells
    449. Bruskin AM, Tyner AL, Wells DE, Showman RM, Klein WH. Accumulation in embryogenesis of five mRNAs enriched in the ectoderm of the sea urchin pluteus. Dev Biol. 1981 Oct 30; 87(2):308-18. PMID: 6169573.
      Citations: 22     Fields:    Translation:AnimalsCells
    450. Richter E, Luger W, Klein W, Korte F, Weger N. Excretion of beta-hexachlorocyclohexane by the rat as influenced by oral paraffin, squalane, and Lutrol E 400. Ecotoxicol Environ Saf. 1981 Sep; 5(3):270-80. PMID: 6170505.
      Citations:    Fields:    Translation:Animals
    451. Malik JK, Lay JP, Klein W, Korte F. Biotransformation and disposition of the coumaphos metabolite 3-chloro-4-methyl-(4-14C)-7-hydroxycoumarin in rats. Arch Toxicol. 1981 Aug; 48(1):51-9. PMID: 7283748.
      Citations:    Fields:    Translation:Animals
    452. Wells DE, Showman RM, Klein WH, Raff RA. Delayed recruitment of maternal histone H3 mRNA in sea urchin embryos. Nature. 1981 Jul 30; 292(5822):477-8. PMID: 7254343.
      Citations: 11     Fields:    Translation:AnimalsCells
    453. Malik JK, Lay JP, Klein W, Korte F. Elimination pattern and biodistribution of [14C]chlorferron in rats. Toxicol Lett. 1981 Mar; 7(6):449-52. PMID: 7245230.
      Citations:    Fields:    Translation:Animals
    454. Lay JP, Klein W, Korte F, Richter E. Metabolism of beta-hexachlorocyclohexane-14C in rats following low dosing in the daily diet. J Environ Sci Health B. 1981; 16(3):227-38. PMID: 6166652.
      Citations: 1     Fields:    Translation:Animals
    455. Malik JK, Lay JP, Klein W, Korte F. Studies on 3-chloro-4-methyl-(4-14C)-7-hydroxycoumarin in rats. Adv Exp Med Biol. 1981; 136 Pt A:839-46. PMID: 7344495.
      Citations:    Fields:    Translation:Animals
    456. Scheunert I, Vockel D, Klein W, Korte F. Fate of 14C-allylalcohol herbicide in soils and crop residues. J Environ Sci Health B. 1981; 16(6):719-42. PMID: 7338596.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    457. Klein WL. Multiple binding states of muscarinic acetylcholine receptors in membranes from neuroblastoma x glioma hybrid cells. Biochem Biophys Res Commun. 1980 Apr 29; 93(4):1058-66. PMID: 7396897.
      Citations: 5     Fields:    Translation:AnimalsCells
    458. Shifrin GS, Klein WL. Regulation of muscarinic acetylcholine receptor concentration in cloned neuroblastoma cells. J Neurochem. 1980 Apr; 34(4):993-9. PMID: 7359145.
      Citations: 8     Fields:    Translation:AnimalsCells
    459. Klein WL. Regulation of muscarinic acetylcholine receptors. Proc West Pharmacol Soc. 1980; 23:449-58. PMID: 7403163.
      Citations:    Fields:    Translation:AnimalsCells
    460. Lay JP, Kamal M, Klein W, Korte F. Fate of 2,5,4'-trichlorobiphenyl in rats. Xenobiotica. 1979 Dec; 9(12):713-21. PMID: 119356.
      Citations: 1     Fields:    Translation:Animals
    461. Valdenaire K, Klein W. [Treatment of diabetic patients with insulin resistance and allergy using des-phe-insulin (author's transl)]. Dtsch Med Wochenschr. 1979 Nov 16; 104(46):1637-9. PMID: 499001.
      Citations: 1     Fields:    Translation:HumansAnimals
    462. Groener JE, Klein W, Van Golde LM. The effect of fasting and refeeding on the composition and synthesis of triacylglycerols, phosphatidylcholines, and phosphatidylethanolamines in rat liver. Arch Biochem Biophys. 1979 Nov; 198(1):287-95. PMID: 507846.
      Citations: 13     Fields:    Translation:Animals
    463. Klein WL, Nathanson N, Nirenberg M. Muscarinic acetylcholine receptor regulation by accelerated rate of receptor loss. Biochem Biophys Res Commun. 1979 Sep 27; 90(2):506-12. PMID: 508317.
      Citations: 11     Fields:    Translation:AnimalsCells
    464. Moza P, Scheunert I, Klein W, Korte F. Studies with 2,4',5-trichlorobiphenyl-14C and 2,2',4,4',6-pentachlorobiphenyl-14C in carrots, sugar beets, and soil. J Agric Food Chem. 1979 Sep-Oct; 27(5):1120-4. PMID: 121130.
      Citations: 6     Fields:    Translation:Animals
    465. Richter E, Lay JP, Klein W, Korte F. Paraffin-stimulated excretion of 2,4,6,2'4'-pentachlorobi[14C]phenyl by rats. Toxicol Appl Pharmacol. 1979 Aug; 50(1):17-23. PMID: 115115.
      Citations: 3     Fields:    Translation:Animals
    466. Siman RG, Klein WL. Cholinergic activity regulates muscarinic receptors in central nervous system cultures. Proc Natl Acad Sci U S A. 1979 Aug; 76(8):4141-5. PMID: 226997.
      Citations: 13     Fields:    Translation:AnimalsCells
    467. Freitag D, Geyer H, Klein W, Kraus AG, Lahaniatis E, Korte F. An approach for comparative screening of the environmental behavior of chemicals. Ecotoxicol Environ Saf. 1979 Jun; 3(2):144-51. PMID: 540557.
      Citations:    Fields:    Translation:AnimalsCellsPHPublic Health
    468. Conradt P, Müller WF, Loose L, Klein W, Coulston F, Korte F. Incorporation of [3H]uridine into RNA under the influence of dieldrin and polychlorinated biphenyls. Ecotoxicol Environ Saf. 1979 Mar; 3(1):10-7. PMID: 94286.
      Citations: 1     Fields:    Translation:AnimalsCells
    469. Richter E, Lay JP, Klein W, Korte F. Enhanced elimination of kepone-14C in rats fed liquid paraffin. J Agric Food Chem. 1979 Jan-Feb; 27(1):187-9. PMID: 84006.
      Citations: 1     Fields:    Translation:Animals
    470. Wold BJ, Klein WH, Hough-Evans BR, Britten RJ, Davidson EH. Sea urchin embryo mRNA sequences expressed in the nuclear RNA of adult tissues. Cell. 1978 Aug; 14(4):941-50. PMID: 688400.
      Citations: 33     Fields:    Translation:AnimalsCells
    471. Klein WH, Thomas TL, Lai C, Scheller RH, Britten RJ, Davidson EH. Characteristics of individual repetitive sequence families in the sea urchin genome studied with cloned repeats. Cell. 1978 Aug; 14(4):889-900. PMID: 688398.
      Citations: 18     Fields:    Translation:AnimalsCells
    472. Nathanson NM, Klein WL, Nirenberg M. Regulation of adenylate cyclase activity mediated by muscarinic acetylcholine receptors. Proc Natl Acad Sci U S A. 1978 Apr; 75(4):1788-91. PMID: 205870.
      Citations: 17     Fields:    Translation:Cells
    473. Galper JB, Klein W, Catterall WA. Muscarinic acetylcholine receptors in developing chick heart. J Biol Chem. 1977 Dec 10; 252(23):8692-9. PMID: 562880.
      Citations: 27     Fields:    Translation:AnimalsCells
    474. Galau GA, Klein WH, Britten RJ, Davidson EH. Significance of rare m RNA sequences in liver. Arch Biochem Biophys. 1977 Mar; 179(2):584-99. PMID: 851359.
      Citations: 15     Fields:    Translation:AnimalsCells
    475. Davidson EH, Klein WH, Britten RJ. Sequence organization in animal DNA and a speculation on hnRNA as a coordinate regulatory transcript. Dev Biol. 1977 Jan; 55(1):69-84. PMID: 832773.
      Citations: 24     Fields:    Translation:AnimalsCells
    476. Galau GA, Klein WH, Davis MM, Wold BJ, Britten RJ, Davidson EH. Structural gene sets active in embryos and adult tissues of the sea urchin. Cell. 1976 Apr; 7(4):487-505. PMID: 986248.
      Citations: 66     Fields:    Translation:AnimalsCells
    477. Kamal M, Weisgerber I, Klein W, Korte F. Contributions to ecological chemistry, CXIV1. Fate of 2,2'-dichlorobiphenyl-14C in rats upon long-term feeding. J Environ Sci Health B. 1976; 11(4):271-87. PMID: 826560.
      Citations:    Fields:    Translation:Animals
    478. Kohli J, Weisgerber I, Klein W, Korte F. Contributions to ecological chemistry CVII1. Fate of lindane-14C in lettuce, endives and soil under outdoor conditions. J Environ Sci Health B. 1976; 11(1):23-32. PMID: 58883.
      Citations: 1     Fields:    Translation:AnimalsPHPublic Health
    479. Haque A, Weisgerber I, Kotzias D, Klein W, Korte F. Contributions to ecological chemistry CXII1. Balance of conversion of buturon-14C in wheat under outdoor conditions. J Environ Sci Health B. 1976; 11(3):211-23. PMID: 977918.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    480. Greb W, Klein W, Coulston F, Golberg L, Korte F. Ecological chemistry. LXXXIII. In vitro metabolism of polychlorinated biphenyls-14-C. Bull Environ Contam Toxicol. 1975 Apr; 13(4):424-32. PMID: 805613.
      Citations: 4     Fields:    Translation:AnimalsCells