VARSHA V GANDHI

TitleProfessor
InstitutionMD Anderson
DepartmentExperimental Therapeutics
Address1881 East Road
Houston TX 77054-3005
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Timofeeva N, Gandhi V. Ibrutinib combinations in CLL therapy: scientific rationale and clinical results. Blood Cancer J. 2021 Apr 29; 11(4):79. PMID: 33927183.
      Citations:    Fields:    
    2. Buettner R, Nguyen LXT, Morales C, Chen MH, Wu X, Chen LS, Hoang DH, Hernandez Vargas S, Pullarkat V, Gandhi V, Marcucci G, Rosen ST. Targeting the metabolic vulnerability of acute myeloid leukemia blasts with a combination of venetoclax and 8-chloro-adenosine. J Hematol Oncol. 2021 Apr 26; 14(1):70. PMID: 33902674.
      Citations:    Fields:    
    3. Bose P, Gandhi V. Managing chronic lymphocytic leukemia in 2020: an update on recent clinical advances with a focus on BTK and BCL-2 inhibitors. Fac Rev. 2021; 10:22. PMID: 33718939.
      Citations:    
    4. Sarkar A, Stellrecht CM, Vangapandu HV, Ayres M, Kaipparettu BA, Park JH, Balakrishnan K, Burks JK, Pandita TK, Hittelman WN, Neelapu SS, Gandhi V. Ataxia-telangiectasia mutated interacts with Parkin and induces mitophagy independent of kinase activity. Evidence from mantle cell lymphoma. Haematologica. 2021 Feb 01; 106(2):495-512. PMID: 32029507.
      Citations: 4     Fields:    
    5. Timofeeva N, Gandhi V. Metabolism meets apoptosis in AML. Leuk Lymphoma. 2021 03; 62(3):514-516. PMID: 33356786.
      Citations:    Fields:    Translation:Humans
    6. Sarkar A, Gandhi V. Activation of ATM kinase by ROS generated during ionophore-induced mitophagy in human T and B cell malignancies. Mol Cell Biochem. 2021 Jan; 476(1):417-423. PMID: 32996079.
      Citations:    Fields:    
    7. Yi X, Sarkar A, Kismali G, Aslan B, Ayres M, Iles LR, Keating MJ, Wierda WG, Long JP, Bertilaccio MTS, Gandhi V. AMG-176, an Mcl-1 Antagonist, Shows Preclinical Efficacy in Chronic Lymphocytic Leukemia. Clin Cancer Res. 2020 07 15; 26(14):3856-3867. PMID: 31937611.
      Citations: 10     Fields:    
    8. Banerjee P, Zhang R, Ivan C, Galletti G, Clise-Dwyer K, Barbaglio F, Scarfò L, Aracil M, Klein C, Wierda W, Plunkett W, Caligaris-Cappio F, Gandhi V, Keating MJ, Bertilaccio MTS. Trabectedin Reveals a Strategy of Immunomodulation in Chronic Lymphocytic Leukemia. Cancer Immunol Res. 2019 12; 7(12):2036-2051. PMID: 31530560.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    9. Jain N, Gandhi V, Wierda W. Ibrutinib and Venetoclax for First-Line Treatment of CLL. Reply. N Engl J Med. 2019 08 22; 381(8):789. PMID: 31433937.
      Citations:    Fields:    Translation:Humans
    10. Chen LS, Keating MJ, Wierda WG, Gandhi V. Induction of apoptosis by MCL-1 inhibitors in chronic lymphocytic leukemia cells. Leuk Lymphoma. 2019 12; 60(12):3063-3066. PMID: 31161836.
      Citations: 1     Fields:    Translation:Humans
    11. Jain N, Keating M, Thompson P, Ferrajoli A, Burger J, Borthakur G, Takahashi K, Estrov Z, Fowler N, Kadia T, Konopleva M, Alvarado Y, Yilmaz M, DiNardo C, Bose P, Ohanian M, Pemmaraju N, Jabbour E, Sasaki K, Kanagal-Shamanna R, Patel K, Jorgensen J, Garg N, Wang X, Sondermann K, Cruz N, Wei C, Ayala A, Plunkett W, Kantarjian H, Gandhi V, Wierda W. Ibrutinib and Venetoclax for First-Line Treatment of CLL. N Engl J Med. 2019 05 30; 380(22):2095-2103. PMID: 31141631.
      Citations: 74     Fields:    Translation:HumansCTClinical Trials
    12. Galan-Cobo A, Sitthideatphaiboon P, Qu X, Poteete A, Pisegna MA, Tong P, Chen PH, Boroughs LK, Rodriguez MLM, Zhang W, Parlati F, Wang J, Gandhi V, Skoulidis F, DeBerardinis RJ, Minna JD, Heymach JV. LKB1 and KEAP1/NRF2 Pathways Cooperatively Promote Metabolic Reprogramming with Enhanced Glutamine Dependence in KRAS-Mutant Lung Adenocarcinoma. Cancer Res. 2019 07 01; 79(13):3251-3267. PMID: 31040157.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    13. Cervantes-Gomez F, Stellrecht CM, Ayres ML, Keating MJ, Wierda WG, Gandhi V. PIM kinase inhibitor, AZD1208, inhibits protein translation and induces autophagy in primary chronic lymphocytic leukemia cells. Oncotarget. 2019 Apr 19; 10(29):2793-2809. PMID: 31073371.
      Citations: 4     Fields:    
    14. Buettner R, Nguyen LXT, Kumar B, Morales C, Liu C, Chen LS, Pemovska T, Synold TW, Palmer J, Thompson R, Li L, Hoang DH, Zhang B, Ghoda L, Kowolik C, Kontro M, Leitch C, Wennerberg K, Yu X, Chen CC, Horne D, Gandhi V, Pullarkat V, Marcucci G, Rosen ST. 8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia. J Cell Physiol. 2019 Feb 15. PMID: 30770553.
      Citations: 4     Fields:    
    15. Bose P, Chen LS, Gandhi V. Ibrutinib dose and clinical outcome in chronic lymphocytic leukemia - learning from the 'real world'. Leuk Lymphoma. 2019 07; 60(7):1603-1605. PMID: 30724681.
      Citations: 1     Fields:    Translation:Humans
    16. Vangapandu HV, Gandhi V. Extracellular Flux Assays to Determine Oxidative Phosphorylation and Glycolysis in Chronic Lymphocytic Leukemia Cells. Methods Mol Biol. 2019; 1881:121-128. PMID: 30350202.
      Citations: 1     Fields:    Translation:HumansCells
    17. Aslan B, Ayres ML, Gandhi V. Ex Vivo Pharmacological Profiling in Chronic Lymphocytic Leukemia Cells. Methods Mol Biol. 2019; 1881:19-25. PMID: 30350194.
      Citations:    Fields:    Translation:HumansCells
    18. Bertilaccio MTS, Zhang R, Banerjee P, Gandhi V. In Vitro Assay to Study CLL and Monocyte Interactions. Methods Mol Biol. 2019; 1881:113-119. PMID: 30350201.
      Citations: 1     Fields:    Translation:HumansCells
    19. Chen W, Fan H, Balakrishnan K, Wang Y, Sun H, Fan Y, Gandhi V, Arnold LA, Peng X. Discovery and Optimization of Novel Hydrogen Peroxide Activated Aromatic Nitrogen Mustard Derivatives as Highly Potent Anticancer Agents. J Med Chem. 2018 10 25; 61(20):9132-9145. PMID: 30247905.
      Citations: 7     Fields:    Translation:HumansCells
    20. Chen LS, Bose P, Cruz ND, Jiang Y, Wu Q, Thompson PA, Feng S, Kroll MH, Qiao W, Huang X, Jain N, Wierda WG, Keating MJ, Gandhi V. A pilot study of lower doses of ibrutinib in patients with chronic lymphocytic leukemia. Blood. 2018 11 22; 132(21):2249-2259. PMID: 30254130.
      Citations: 17     Fields:    Translation:HumansCellsCTClinical Trials
    21. Elsayed AH, Cao X, Crews KR, Gandhi V, Plunkett W, Rubnitz JE, Ribeiro RC, Pounds SB, Lamba JK. Comprehensive Ara-C SNP score predicts leukemic cell intracellular ara-CTP levels in pediatric acute myeloid leukemia patients. Pharmacogenomics. 2018 09 01; 19(14):1101-1110. PMID: 30088438.
      Citations: 1     Fields:    Translation:Humans
    22. Abou Dalle I, Cortes JE, Pinnamaneni P, Lamothe B, Diaz Duque A, Randhawa J, Pemmaraju N, Jabbour E, Ferrajoli A, Wierda WG, Estrov Z, Konopleva M, Ravandi F, Alvarado Y, Borthakur G, Gandhi V, Kantarjian HM. A Pilot Phase II Study of Erlotinib for the Treatment of Patients with Relapsed/Refractory Acute Myeloid Leukemia. Acta Haematol. 2018; 140(1):30-39. PMID: 30071517.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    23. Vangapandu HV, Alston B, Morse J, Ayres ML, Wierda WG, Keating MJ, Marszalek JR, Gandhi V. Biological and metabolic effects of IACS-010759, an OxPhos inhibitor, on chronic lymphocytic leukemia cells. Oncotarget. 2018 May 18; 9(38):24980-24991. PMID: 29861847.
      Citations: 11     Fields:    
    24. Cortes J, Tamura K, DeAngelo DJ, de Bono J, Lorente D, Minden M, Uy GL, Kantarjian H, Chen LS, Gandhi V, Godin R, Keating K, McEachern K, Vishwanathan K, Pease JE, Dean E. Phase I studies of AZD1208, a proviral integration Moloney virus kinase inhibitor in solid and haematological cancers. Br J Cancer. 2018 05; 118(11):1425-1433. PMID: 29765150.
      Citations: 12     Fields:    Translation:HumansCellsCTClinical Trials
    25. Patel VK, Lamothe B, Ayres ML, Gay J, Cheung JP, Balakrishnan K, Ivan C, Morse J, Nelson M, Keating MJ, Wierda WG, Marszalek JR, Gandhi V. Pharmacodynamics and proteomic analysis of acalabrutinib therapy: similarity of on-target effects to ibrutinib and rationale for combination therapy. Leukemia. 2018 04; 32(4):920-930. PMID: 29099493.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    26. Bose P, Gandhi V. Recent therapeutic advances in chronic lymphocytic leukemia. F1000Res. 2017; 6:1924. PMID: 29152232.
      Citations: 5     Fields:    
    27. Vangapandu HV, Chen H, Wierda WG, Keating MJ, Korkut A, Gandhi V. Proteomics profiling identifies induction of caveolin-1 in chronic lymphocytic leukemia cells by bone marrow stromal cells. Leuk Lymphoma. 2018 06; 59(6):1427-1438. PMID: 28971726.
      Citations: 2     Fields:    Translation:HumansCells
    28. Vangapandu HV, Ayres ML, Bristow CA, Wierda WG, Keating MJ, Balakrishnan K, Stellrecht CM, Gandhi V. The Stromal Microenvironment Modulates Mitochondrial Oxidative Phosphorylation in Chronic Lymphocytic Leukemia Cells. Neoplasia. 2017 Oct; 19(10):762-771. PMID: 28863345.
      Citations: 9     Fields:    Translation:HumansCells
    29. Vangapandu HV, Havranek O, Ayres ML, Kaipparettu BA, Balakrishnan K, Wierda WG, Keating MJ, Davis RE, Stellrecht CM, Gandhi V. B-cell Receptor Signaling Regulates Metabolism in Chronic Lymphocytic Leukemia. Mol Cancer Res. 2017 12; 15(12):1692-1703. PMID: 28835371.
      Citations: 12     Fields:    Translation:HumansCells
    30. Stellrecht CM, Chen LS, Ayres ML, Dennison JB, Shentu S, Chen Y, Keating MJ, Wierda WG, Gandhi V. Chlorinated adenosine analogue induces AMPK and autophagy in chronic lymphocytic leukaemia cells during therapy. Br J Haematol. 2017 10; 179(2):266-271. PMID: 28737232.
      Citations: 6     Fields:    Translation:HumansCells
    31. Short NJ, Kantarjian H, Ravandi F, Huang X, Xiao L, Garcia-Manero G, Plunkett W, Gandhi V, Sasaki K, Pemmaraju N, Daver NG, Borthakur G, Jain N, Konopleva M, Estrov Z, Kadia TM, Wierda WG, DiNardo CD, Brandt M, O'Brien SM, Cortes JE, Jabbour E. A phase I/II randomized trial of clofarabine or fludarabine added to idarubicin and cytarabine for adults with relapsed or refractory acute myeloid leukemia. Leuk Lymphoma. 2018 04; 59(4):813-820. PMID: 28718728.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    32. Jabbour E, Short NJ, Ravandi F, Huang X, Xiao L, Garcia-Manero G, Plunkett W, Gandhi V, Sasaki K, Pemmaraju N, Daver NG, Borthakur G, Jain N, Konopleva M, Estrov Z, Kadia TM, Wierda WG, DiNardo CD, Brandt M, O'Brien SM, Cortes JE, Kantarjian H. A randomized phase 2 study of idarubicin and cytarabine with clofarabine or fludarabine in patients with newly diagnosed acute myeloid leukemia. Cancer. 2017 Nov 15; 123(22):4430-4439. PMID: 28708931.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    33. Yang Q, Modi P, Korkut A, Fernandes SM, Hanna J, Brown JR, Gandhi V. Changes in Bcl-2 Family Protein Profile During Idelalisib Therapy Mimic Those During Duvelisib Therapy in Chronic Lymphocytic Leukemia Lymphocytes. JCO Precis Oncol. 2017; 1. PMID: 32913964.
      Citations:    
    34. Vangapandu HV, Jain N, Gandhi V. Duvelisib: a phosphoinositide-3 kinase d/? inhibitor for chronic lymphocytic leukemia. Expert Opin Investig Drugs. 2017 May; 26(5):625-632. PMID: 28388280.
      Citations: 13     Fields:    Translation:HumansAnimals
    35. Jain N, Balakrishnan K, Ferrajoli A, O'Brien SM, Burger JA, Kadia TM, Cortes JE, Ayres ML, Tambaro FP, Keating MJ, Gandhi V, Wierda WG. A phase I-II trial of fludarabine, bendamustine and rituximab (FBR) in previously treated patients with CLL. Oncotarget. 2017 Mar 28; 8(13):22104-22112. PMID: 27655665.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    36. Wang Y, Fan H, Balakrishnan K, Lin Z, Cao S, Chen W, Fan Y, Guthrie QA, Sun H, Teske KA, Gandhi V, Arnold LA, Peng X. Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells. Eur J Med Chem. 2017 Jun 16; 133:197-207. PMID: 28388522.
      Citations: 5     Fields:    Translation:HumansCells
    37. Baljevic M, Zaman S, Baladandayuthapani V, Lin YH, de Partovi CM, Berkova Z, Amini B, Thomas SK, Shah JJ, Weber DM, Fu M, Cleeland CS, Wang XS, Stellrecht CM, Davis RE, Gandhi V, Orlowski RZ. Phase II study of the c-MET inhibitor tivantinib (ARQ 197) in patients with relapsed or relapsed/refractory multiple myeloma. Ann Hematol. 2017 Jun; 96(6):977-985. PMID: 28337527.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    38. Modi P, Balakrishnan K, Yang Q, Wierda WG, Keating MJ, Gandhi V. Idelalisib and bendamustine combination is synergistic and increases DNA damage response in chronic lymphocytic leukemia cells. Oncotarget. 2017 Mar 07; 8(10):16259-16274. PMID: 28187444.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    39. Bose P, Gandhi V, Konopleva M. Pathways and mechanisms of venetoclax resistance. Leuk Lymphoma. 2017 09; 58(9):1-17. PMID: 28140720.
      Citations: 39     Fields:    Translation:HumansAnimals
    40. Gandhi V, Jalali R. A Conference of New Ideas in Cancer-Challenging Dogmas. Cancer Res. 2017 01 15; 77(2):234-237. PMID: 28062401.
      Citations:    Fields:    Translation:Humans
    41. Patel V, Balakrishnan K, Bibikova E, Ayres M, Keating MJ, Wierda WG, Gandhi V. Comparison of Acalabrutinib, A Selective Bruton Tyrosine Kinase Inhibitor, with Ibrutinib in Chronic Lymphocytic Leukemia Cells. Clin Cancer Res. 2017 Jul 15; 23(14):3734-3743. PMID: 28034907.
      Citations: 24     Fields:    Translation:HumansCells
    42. Patel VM, Balakrishnan K, Douglas M, Tibbitts T, Xu EY, Kutok JL, Ayers M, Sarkar A, Guerrieri R, Wierda WG, O'Brien S, Jain N, Stern HM, Gandhi V. Duvelisib treatment is associated with altered expression of apoptotic regulators that helps in sensitization of chronic lymphocytic leukemia cells to venetoclax (ABT-199). Leukemia. 2017 09; 31(9):1872-1881. PMID: 28017967.
      Citations: 22     Fields:    Translation:HumansCellsCTClinical Trials
    43. Kadia TM, Gandhi V. Nelarabine in the treatment of pediatric and adult patients with T-cell acute lymphoblastic leukemia and lymphoma. Expert Rev Hematol. 2017 Jan; 10(1):1-8. PMID: 27869523.
      Citations: 5     Fields:    Translation:HumansAnimals
    44. Mendes VIS, Bartholomeusz GA, Ayres M, Gandhi V, Salvador JAR. Corrigendum to "Synthesis and cytotoxic activity of novel A-ring cleaved ursolic acid derivatives in human non-small cell lung cancer cells" [Eur. J. Med. Chem. 123 (2016) 317-331]. Eur J Med Chem. 2016 11 29; 124:1004-1005. PMID: 27783971.
      Citations:    Fields:    
    45. Phillip CJ, Zaman S, Shentu S, Balakrishnan K, Zhang J, Baladandayuthapani V, Taverna P, Redkar S, Wang M, Stellrecht CM, Gandhi V. Erratum to: Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines. J Hematol Oncol. 2016 10 13; 9(1):110. PMID: 27737688.
      Citations: 1     Fields:    
    46. Bose P, Gandhi VV, Keating MJ. Pharmacokinetic and pharmacodynamic evaluation of ibrutinib for the treatment of chronic lymphocytic leukemia: rationale for lower doses. Expert Opin Drug Metab Toxicol. 2016 Nov; 12(11):1381-1392. PMID: 27686109.
      Citations: 7     Fields:    
    47. Patel P, Vora H, Aggarwal BB, Gandhi V, Mehta K, Pathak S. Prevention and Treatment of Cancer: Hypes and Hopes 6th International Translational Cancer Research Conference. Anticancer Res. 2016 09; 36(9):4971-5. PMID: 27630358.
      Citations:    Fields:    Translation:Humans
    48. Mendes VIS, Bartholomeusz GA, Ayres M, Gandhi V, Salvador JAR. Synthesis and cytotoxic activity of novel A-ring cleaved ursolic acid derivatives in human non-small cell lung cancer cells. Eur J Med Chem. 2016 Nov 10; 123:317-331. PMID: 27484517.
      Citations: 5     Fields:    Translation:HumansCells
    49. Balakrishnan K, Fu M, Onida F, Wierda WG, Keating MJ, Gandhi V. Reactivation of Smac-mediated apoptosis in chronic lymphocytic leukemia cells: mechanistic studies of Smac mimetic. Oncotarget. 2016 Jun 28; 7(26):39458-39472. PMID: 27223062.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    50. Yang Q, Chen LS, Ha MJ, Do KA, Neelapu SS, Gandhi V. Idelalisib Impacts Cell Growth through Inhibiting Translation-Regulatory Mechanisms in Mantle Cell Lymphoma. Clin Cancer Res. 2017 Jan 01; 23(1):181-192. PMID: 27342398.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    51. Chen LS, Yang JY, Liang H, Cortes JE, Gandhi V. Protein profiling identifies mTOR pathway modulation and cytostatic effects of Pim kinase inhibitor, AZD1208, in acute myeloid leukemia. Leuk Lymphoma. 2016 12; 57(12):2863-2873. PMID: 27054578.
      Citations: 5     Fields:    Translation:HumansCells
    52. Lamothe B, Wierda WG, Keating MJ, Gandhi V. Carfilzomib Triggers Cell Death in Chronic Lymphocytic Leukemia by Inducing Proapoptotic and Endoplasmic Reticulum Stress Responses. Clin Cancer Res. 2016 Sep 15; 22(18):4712-26. PMID: 27026200.
      Citations: 8     Fields:    Translation:HumansCells
    53. Sarkar A, Balakrishnan K, Chen J, Patel V, Neelapu SS, McMurray JS, Gandhi V. Molecular evidence of Zn chelation of the procaspase activating compound B-PAC-1 in B cell lymphoma. Oncotarget. 2016 Jan 19; 7(3):3461-76. PMID: 26658105.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    54. Patel V, Keating MJ, Wierda WG, Gandhi V. Preclinical combination of TP-0903, an AXL inhibitor and B-PAC-1, a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia. Leuk Lymphoma. 2016; 57(6):1494-7. PMID: 26440741.
      Citations: 5     Fields:    Translation:HumansCells
    55. Cervantes-Gomez F, Lavergne B, Keating MJ, Wierda WG, Gandhi V. Combination of Pim kinase inhibitors and Bcl-2 antagonists in chronic lymphocytic leukemia cells. Leuk Lymphoma. 2016 Feb; 57(2):436-444. PMID: 26088877.
      Citations: 5     Fields:    
    56. Kearney AY, Fan YH, Giri U, Saigal B, Gandhi V, Heymach JV, Zurita AJ. 8-Chloroadenosine Sensitivity in Renal Cell Carcinoma Is Associated with AMPK Activation and mTOR Pathway Inhibition. PLoS One. 2015; 10(8):e0135962. PMID: 26313261.
      Citations: 5     Fields:    Translation:HumansCells
    57. Zaman S, Wang R, Gandhi V. Targeting executioner procaspase-3 with the procaspase-activating compound B-PAC-1 induces apoptosis in multiple myeloma cells. Exp Hematol. 2015 Nov; 43(11):951-962.e3. PMID: 26257207.
      Citations: 6     Fields:    Translation:HumansCells
    58. Wang J, Yin H, Panandikar A, Gandhi V, Sen S. Elevated cyclin A associated kinase activity promotes sensitivity of metastatic human cancer cells to DNA antimetabolite drug. Int J Oncol. 2015 Aug; 47(2):782-90. PMID: 26058363.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    59. Balakrishnan K, Peluso M, Fu M, Rosin NY, Burger JA, Wierda WG, Keating MJ, Faia K, O'Brien S, Kutok JL, Gandhi V. The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL. Leukemia. 2015 Sep; 29(9):1811-22. PMID: 25917267.
      Citations: 58     Fields:    Translation:HumansCells
    60. Cervantes-Gomez F, Lamothe B, Woyach JA, Wierda WG, Keating MJ, Balakrishnan K, Gandhi V. Pharmacological and Protein Profiling Suggests Venetoclax (ABT-199) as Optimal Partner with Ibrutinib in Chronic Lymphocytic Leukemia. Clin Cancer Res. 2015 Aug 15; 21(16):3705-15. PMID: 25829398.
      Citations: 73     Fields:    Translation:HumansCells
    61. Zaman S, Shentu S, Yang J, He J, Orlowski RZ, Stellrecht CM, Gandhi V. Targeting the pro-survival protein MET with tivantinib (ARQ 197) inhibits growth of multiple myeloma cells. Neoplasia. 2015 Mar; 17(3):289-300. PMID: 25810013.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    62. Yang Q, Modi P, Newcomb T, Quéva C, Gandhi V. Idelalisib: First-in-Class PI3K Delta Inhibitor for the Treatment of Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, and Follicular Lymphoma. Clin Cancer Res. 2015 Apr 01; 21(7):1537-42. PMID: 25670221.
      Citations: 57     Fields:    Translation:Humans
    63. Lamothe B, Cervantes-Gomez F, Sivina M, Wierda WG, Keating MJ, Gandhi V. Proteasome inhibitor carfilzomib complements ibrutinib's action in chronic lymphocytic leukemia. Blood. 2015 Jan 08; 125(2):407-10. PMID: 25573971.
      Citations: 12     Fields:    Translation:HumansCells
    64. Patel V, Balakrishnan K, Keating MJ, Wierda WG, Gandhi V. Expression of executioner procaspases and their activation by a procaspase-activating compound in chronic lymphocytic leukemia cells. Blood. 2015 Feb 12; 125(7):1126-36. PMID: 25538042.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    65. Balakrishnan K, Burger JA, Fu M, Doifode T, Wierda WG, Gandhi V. Regulation of Mcl-1 expression in context to bone marrow stromal microenvironment in chronic lymphocytic leukemia. Neoplasia. 2014 Dec; 16(12):1036-46. PMID: 25499217.
      Citations: 19     Fields:    Translation:HumansCells
    66. Mehta K, Gandhi V, Pathak S, Aggarwal BB, Grover RK. Multi-targeted approach to cancer treatment: an international translational cancer research symposium. Anticancer Res. 2014 Nov; 34(11):6791-5. PMID: 25368293.
      Citations: 4     Fields:    Translation:HumansCells
    67. Chen LS, Keating MJ, Gandhi V. Blood collection methods affect cellular protein integrity: implications for clinical trial biomarkers and ZAP-70 in CLL. Blood. 2014 Aug 14; 124(7):1192-5. PMID: 25124785.
      Citations: 2     Fields:    Translation:Humans
    68. Chen W, Balakrishnan K, Kuang Y, Han Y, Fu M, Gandhi V, Peng X. Reactive oxygen species (ROS) inducible DNA cross-linking agents and their effect on cancer cells and normal lymphocytes. J Med Chem. 2014 Jun 12; 57(11):4498-510. PMID: 24801734.
      Citations: 19     Fields:    Translation:HumansCells
    69. El-Mabhouh AA, Ayres ML, Shpall EJ, Baladandayuthapani V, Keating MJ, Wierda WG, Gandhi V. Evaluation of bendamustine in combination with fludarabine in primary chronic lymphocytic leukemia cells. Blood. 2014 Jun 12; 123(24):3780-9. PMID: 24747434.
      Citations: 12     Fields:    Translation:HumansCells
    70. Gandhi V, Plunkett W, Cortes JE. Omacetaxine: a protein translation inhibitor for treatment of chronic myelogenous leukemia. Clin Cancer Res. 2014 Apr 01; 20(7):1735-40. PMID: 24501394.
      Citations: 32     Fields:    Translation:HumansCells
    71. Zaman S, Wang R, Gandhi V. Targeting the apoptosis pathway in hematologic malignancies. Leuk Lymphoma. 2014 Sep; 55(9):1980-92. PMID: 24295132.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    72. Yang Q, Chen LS, Gandhi V. Mechanism-based combinations with Pim kinase inhibitors in cancer treatments. Curr Pharm Des. 2014; 20(42):6670-81. PMID: 25341939.
      Citations: 1     Fields:    Translation:HumansAnimals
    73. Faderl S, Balakrishnan K, Thomas DA, Ravandi F, Borthakur G, Burger J, Ferrajoli A, Cortes J, O'Brien S, Kadia T, Feliu J, Plunkett W, Gandhi V, Kantarjian HM. Phase I and extension study of clofarabine plus cyclophosphamide in patients with relapsed/refractory acute lymphoblastic leukemia. Clin Lymphoma Myeloma Leuk. 2014 Jun; 14(3):231-8. PMID: 24440659.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    74. Phillip CJ, Zaman S, Shentu S, Balakrishnan K, Zhang J, Baladandayuthapani V, Taverna P, Redkar S, Wang M, Stellrecht CM, Gandhi V. Targeting MET kinase with the small-molecule inhibitor amuvatinib induces cytotoxicity in primary myeloma cells and cell lines. J Hematol Oncol. 2013 Dec 10; 6:92. PMID: 24326130.
      Citations: 11     Fields:    Translation:HumansCells
    75. Balakrishnan K, Gandhi V. Uncoupling endoplasmic reticulum stress and autophagy: a potential implication for chronic lymphocytic leukemia therapy. Leuk Lymphoma. 2013 Dec; 54(12):2581-3. PMID: 23656199.
      Citations:    Fields:    Translation:Humans
    76. Gandhi V. A new feature in Leukemia & Lymphoma: "Emerging drug profile". Leuk Lymphoma. 2013 Oct; 54(10):2131-2. PMID: 24041378.
      Citations:    Fields:    Translation:Humans
    77. Patel V, Chen LS, Wierda WG, Balakrishnan K, Gandhi V. Impact of bone marrow stromal cells on Bcl-2 family members in chronic lymphocytic leukemia. Leuk Lymphoma. 2014 Apr; 55(4):899-910. PMID: 23837491.
      Citations: 12     Fields:    Translation:HumansCells
    78. Cao X, Mitra AK, Pounds S, Crews KR, Gandhi V, Plunkett W, Dolan ME, Hartford C, Raimondi S, Campana D, Downing J, Rubnitz JE, Ribeiro RC, Lamba JK. RRM1 and RRM2 pharmacogenetics: association with phenotypes in HapMap cell lines and acute myeloid leukemia patients. Pharmacogenomics. 2013 Sep; 14(12):1449-66. PMID: 24024897.
      Citations: 12     Fields:    Translation:HumansCells
    79. Yang Q, Chen LS, Neelapu SS, Gandhi V. Combination of Pim kinase inhibitor SGI-1776 and bendamustine in B-cell lymphoma. Clin Lymphoma Myeloma Leuk. 2013 Sep; 13 Suppl 2:S355-62. PMID: 24290221.
      Citations: 8     Fields:    Translation:HumansCells
    80. Cervantes-Gomez F, Chen LS, Orlowski RZ, Gandhi V. Biological effects of the Pim kinase inhibitor, SGI-1776, in multiple myeloma. Clin Lymphoma Myeloma Leuk. 2013 Sep; 13 Suppl 2:S317-29. PMID: 23988451.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    81. Balakrishnan K, Gandhi V. Bcl-2 antagonists: a proof of concept for CLL therapy. Invest New Drugs. 2013 Oct; 31(5):1384-94. PMID: 23907405.
      Citations: 14     Fields:    Translation:HumansAnimals
    82. DiNardo CD, O'Brien S, Gandhi VV, Ravandi F. Elacytarabine (CP-4055) in the treatment of acute myeloid leukemia. Future Oncol. 2013 Aug; 9(8):1073-82. PMID: 23902239.
      Citations: 4     Fields:    Translation:Humans
    83. Sandoval MR, Balakrishnan K, Luthra R, Keating M, Gandhi V. DNA repair initiation induces expression of ribonucleotide reductase in human chronic lymphocytic leukemia cells. Leuk Lymphoma. 2014 Apr; 55(4):876-83. PMID: 23772636.
      Citations: 2     Fields:    Translation:HumansCells
    84. Balakrishnan K, Ravandi F, Bantia S, Franklin A, Gandhi V. Preclinical and clinical evaluation of forodesine in pediatric and adult B-cell acute lymphoblastic leukemia. Clin Lymphoma Myeloma Leuk. 2013 Aug; 13(4):458-66. PMID: 23773454.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    85. Gandhi V, Mehta K, Pathak S, Aggarwal BB. Meeting report: leaders in translational cancer research meet in Udaipur, a historical town of India: an International Symposium onTranslational Cancer Research: Cancer Prevention. Udaipur, Rajasthan, India, december 16-19, 2011. Anticancer Res. 2013 Apr; 33(4):1777-81. PMID: 23564834.
      Citations:    Fields:    Translation:HumansAnimalsCells
    86. Byers LA, Diao L, Wang J, Saintigny P, Girard L, Peyton M, Shen L, Fan Y, Giri U, Tumula PK, Nilsson MB, Gudikote J, Tran H, Cardnell RJ, Bearss DJ, Warner SL, Foulks JM, Kanner SB, Gandhi V, Krett N, Rosen ST, Kim ES, Herbst RS, Blumenschein GR, Lee JJ, Lippman SM, Ang KK, Mills GB, Hong WK, Weinstein JN, Wistuba II, Coombes KR, Minna JD, Heymach JV. An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clin Cancer Res. 2013 Jan 01; 19(1):279-90. PMID: 23091115.
      Citations: 351     Fields:    Translation:HumansAnimalsCells
    87. Yang Q, Chen LS, Neelapu SS, Miranda RN, Medeiros LJ, Gandhi V. Transcription and translation are primary targets of Pim kinase inhibitor SGI-1776 in mantle cell lymphoma. Blood. 2012 Oct 25; 120(17):3491-500. PMID: 22955922.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    88. Balakrishnan K, Aggarwal S, Wierda W, Gandhi V. Bax and Bak are required for apogossypolone, a BH3-mimetic, induced apoptosis in chronic lymphocytic leukemia cells. Leuk Lymphoma. 2013 May; 54(5):1097-100. PMID: 22866921.
      Citations: 8     Fields:    Translation:HumansAnimals
    89. McBrayer SK, Yarrington M, Qian J, Feng G, Shanmugam M, Gandhi V, Krett NL, Rosen ST. Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms. PLoS One. 2012; 7(7):e41455. PMID: 22848499.
      Citations: 8     Fields:    Translation:HumansCells
    90. Peng X, Gandhi V. ROS-activated anticancer prodrugs: a new strategy for tumor-specific damage. Ther Deliv. 2012 Jul; 3(7):823-33. PMID: 22900465.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    91. Gandhi V, Balakrishnan K. CCL2 in chronic lymphocytic leukemia: a macro in microenvironment? Leuk Lymphoma. 2012 Oct; 53(10):1849-50. PMID: 22563818.
      Citations: 2     Fields:    Translation:Humans
    92. Jabbour E, Garcia-Manero G, Cortes J, Ravandi F, Plunkett W, Gandhi V, Faderl S, O'Brien S, Borthakur G, Kadia T, Burger J, Konopleva M, Brandt M, Huang X, Kantarjian H. Twice-daily fludarabine and cytarabine combination with or without gentuzumab ozogamicin is effective in patients with relapsed/refractory acute myeloid leukemia, high-risk myelodysplastic syndrome, and blast- phase chronic myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2012 Aug; 12(4):244-51. PMID: 22534616.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    93. Pillai RN, Chen LS, Ayres ML, Nowak BJ, Thomas MW, Shpall EJ, Keating MJ, Gandhi V. Multifaceted actions of 8-amino-adenosine kill BCR-ABL positive cells. Leuk Lymphoma. 2012 Oct; 53(10):2024-32. PMID: 22448923.
      Citations: 1     Fields:    Translation:HumansCells
    94. Balakrishnan K, Gandhi V. Protein kinases: emerging therapeutic targets in chronic lymphocytic leukemia. Expert Opin Investig Drugs. 2012 Apr; 21(4):409-23. PMID: 22409342.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    95. Ponader S, Chen SS, Buggy JJ, Balakrishnan K, Gandhi V, Wierda WG, Keating MJ, O'Brien S, Chiorazzi N, Burger JA. The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo. Blood. 2012 Feb 02; 119(5):1182-9. PMID: 22180443.
      Citations: 253     Fields:    Translation:HumansAnimalsCells
    96. Tam CS, Gandhi V. Modifying the immune system to treat chronic lymphocytic leukemia. Leuk Lymphoma. 2012 Feb; 53(2):177-8. PMID: 21895547.
      Citations:    Fields:    Translation:Humans
    97. Kuang Y, Balakrishnan K, Gandhi V, Peng X. Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs. J Am Chem Soc. 2011 Dec 07; 133(48):19278-81. PMID: 22035519.
      Citations: 46     Fields:    Translation:HumansCells
    98. Cervantes-Gomez F, Nimmanapalli R, Gandhi V. ATP analog enhances the actions of a heat shock protein 90 inhibitor in multiple myeloma cells. J Pharmacol Exp Ther. 2011 Nov; 339(2):545-54. PMID: 21821695.
      Citations: 3     Fields:    Translation:HumansCells
    99. Faderl S, Garcia-Manero G, Jabbour E, Ravandi F, Borthakur G, Estrov Z, Gandhi V, Byrd AL, Kwari M, Cortes J, Kantarjian HM. A randomized study of 2 dose levels of intravenous clofarabine in the treatment of patients with higher-risk myelodysplastic syndrome. Cancer. 2012 Feb 01; 118(3):722-8. PMID: 21751197.
      Citations: 12     Fields:    Translation:Humans
    100. Balakrishnan K, Gandhi V. The micros in harmony: microRNA and microenvironment. Leuk Lymphoma. 2011 Sep; 52(9):1626-9. PMID: 21740342.
      Citations:    Fields:    Translation:HumansCells
    101. Mitra AK, Crews KR, Pounds S, Cao X, Feldberg T, Ghodke Y, Gandhi V, Plunkett W, Dolan ME, Hartford C, Raimondi S, Campana D, Downing J, Rubnitz JE, Ribeiro RC, Lamba JK. Genetic variants in cytosolic 5'-nucleotidase II are associated with its expression and cytarabine sensitivity in HapMap cell lines and in patients with acute myeloid leukemia. J Pharmacol Exp Ther. 2011 Oct; 339(1):9-23. PMID: 21712425.
      Citations: 24     Fields:    Translation:HumansCells
    102. Chen LS, Redkar S, Taverna P, Cortes JE, Gandhi V. Mechanisms of cytotoxicity to Pim kinase inhibitor, SGI-1776, in acute myeloid leukemia. Blood. 2011 Jul 21; 118(3):693-702. PMID: 21628411.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    103. Lamba JK, Crews KR, Pounds SB, Cao X, Gandhi V, Plunkett W, Razzouk BI, Lamba V, Baker SD, Raimondi SC, Campana D, Pui CH, Downing JR, Rubnitz JE, Ribeiro RC. Identification of predictive markers of cytarabine response in AML by integrative analysis of gene-expression profiles with multiple phenotypes. Pharmacogenomics. 2011 Mar; 12(3):327-39. PMID: 21449673.
      Citations: 11     Fields:    Translation:Humans
    104. Zhang H, Gogada R, Yadav N, Lella RK, Badeaux M, Ayres M, Gandhi V, Tang DG, Chandra D. Defective molecular timer in the absence of nucleotides leads to inefficient caspase activation. PLoS One. 2011 Jan 27; 6(1):e16379. PMID: 21297999.
      Citations: 8     Fields:    Translation:HumansCells
    105. Gandhi V. Yet another nucleoside analog for pancreatic cancer. Gastroenterology. 2011 Feb; 140(2):400-4. PMID: 21172332.
      Citations:    Fields:    Translation:HumansAnimalsCells
    106. Gandhi V. Targeting kinases in CML CLL. Blood. 2010 Sep 23; 116(12):1999-2000. PMID: 20864583.
      Citations:    Fields:    
    107. Dennison JB, Shanmugam M, Ayres ML, Qian J, Krett NL, Medeiros LJ, Neelapu SS, Rosen ST, Gandhi V. 8-Aminoadenosine inhibits Akt/mTOR and Erk signaling in mantle cell lymphoma. Blood. 2010 Dec 16; 116(25):5622-30. PMID: 20844237.
      Citations: 13     Fields:    Translation:HumansCells
    108. Chen LS, Balakrishnan K, Gandhi V. Inflammation and survival pathways: chronic lymphocytic leukemia as a model system. Biochem Pharmacol. 2010 Dec 15; 80(12):1936-45. PMID: 20696142.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    109. Al-Kali A, Gandhi V, Ayoubi M, Keating M, Ravandi F. Forodesine: review of preclinical and clinical data. Future Oncol. 2010 Aug; 6(8):1211-7. PMID: 20799866.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    110. Chen R, Chubb S, Cheng T, Hawtin RE, Gandhi V, Plunkett W. Responses in mantle cell lymphoma cells to SNS-032 depend on the biological context of each cell line. Cancer Res. 2010 Aug 15; 70(16):6587-97. PMID: 20663900.
      Citations: 14     Fields:    Translation:HumansCells
    111. Gandhi V, Mehta K, Pathak S, Ravindran B, Mishra S, Aggarwal BB. City of temples discusses signaling templates in cancer cells. Third International Symposium on Translational Cancer Research: Cell Signaling & Cancer Therapy. Bhubaneswar, Orissa, India, December 18th through 21st, 2009. Anticancer Res. 2010 Jun; 30(6):2477-80. PMID: 20651411.
      Citations:    Fields:    Translation:HumansAnimalsCells
    112. Balakrishnan K, Burger JA, Quiroga MP, Henneberg M, Ayres ML, Wierda WG, Gandhi V. Influence of bone marrow stromal microenvironment on forodesine-induced responses in CLL primary cells. Blood. 2010 Aug 19; 116(7):1083-91. PMID: 20442367.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    113. Lyu MA, Rai D, Ahn KS, Sung B, Cheung LH, Marks JW, Aggarwal BB, Aguiar RC, Gandhi V, Rosenblum MG. The rGel/BLyS fusion toxin inhibits diffuse large B-cell lymphoma growth in vitro and in vivo. Neoplasia. 2010 May; 12(5):366-75. PMID: 20454508.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    114. Balakrishnan K, Verma D, O'Brien S, Kilpatrick JM, Chen Y, Tyler BF, Bickel S, Bantia S, Keating MJ, Kantarjian H, Gandhi V, Ravandi F. Phase 2 and pharmacodynamic study of oral forodesine in patients with advanced, fludarabine-treated chronic lymphocytic leukemia. Blood. 2010 Aug 12; 116(6):886-92. PMID: 20427701.
      Citations: 13     Fields:    Translation:HumansCellsCTClinical Trials
    115. Faderl S, Garcia-Manero G, Estrov Z, Ravandi F, Borthakur G, Cortes JE, O'Brien S, Gandhi V, Plunkett W, Byrd A, Kwari M, Kantarjian HM. Oral clofarabine in the treatment of patients with higher-risk myelodysplastic syndrome. J Clin Oncol. 2010 Jun 01; 28(16):2755-60. PMID: 20421540.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    116. Dennison JB, Ayres ML, Kaluarachchi K, Plunkett W, Gandhi V. Intracellular succinylation of 8-chloroadenosine and its effect on fumarate levels. J Biol Chem. 2010 Mar 12; 285(11):8022-30. PMID: 20064937.
      Citations: 3     Fields:    Translation:HumansCells
    117. Frey JA, Gandhi V. 8-Amino-adenosine inhibits multiple mechanisms of transcription. Mol Cancer Ther. 2010 Jan; 9(1):236-45. PMID: 20053765.
      Citations: 10     Translation:HumansCells
    118. Gandhi V, Burger JA. Bendamustine in B-Cell Malignancies: The New 46-Year-Old Kid on the Block. Clin Cancer Res. 2009 Dec 15; 15(24):7456-7461. PMID: 19996200.
      Citations: 6     Fields:    
    119. Chen LS, Du-Cuny L, Vethantham V, Hawke DH, Manley JL, Zhang S, Gandhi V. Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues. Biochem Pharmacol. 2010 Mar 01; 79(5):669-77. PMID: 19814999.
      Citations: 13     Fields:    Translation:Animals
    120. Burger JA, Gandhi V. The lymphatic tissue microenvironments in chronic lymphocytic leukemia: in vitro models and the significance of CD40-CD154 interactions. Blood. 2009 Sep 17; 114(12):2560-1; author reply 2561-2. PMID: 19762501.
      Citations: 8     Fields:    Translation:Humans
    121. Kurtova AV, Balakrishnan K, Chen R, Ding W, Schnabl S, Quiroga MP, Sivina M, Wierda WG, Estrov Z, Keating MJ, Shehata M, Jäger U, Gandhi V, Kay NE, Plunkett W, Burger JA. Diverse marrow stromal cells protect CLL cells from spontaneous and drug-induced apoptosis: development of a reliable and reproducible system to assess stromal cell adhesion-mediated drug resistance. Blood. 2009 Nov 12; 114(20):4441-50. PMID: 19762485.
      Citations: 135     Fields:    Translation:HumansAnimalsCells
    122. Chen LS, Redkar S, Bearss D, Wierda WG, Gandhi V. Pim kinase inhibitor, SGI-1776, induces apoptosis in chronic lymphocytic leukemia cells. Blood. 2009 Nov 05; 114(19):4150-7. PMID: 19734450.
      Citations: 76     Fields:    Translation:HumansCells
    123. Dennison JB, Balakrishnan K, Gandhi V. Preclinical activity of 8-chloroadenosine with mantle cell lymphoma: roles of energy depletion and inhibition of DNA and RNA synthesis. Br J Haematol. 2009 Nov; 147(3):297-307. PMID: 19709085.
      Citations: 18     Fields:    Translation:HumansCells
    124. Shanmugam M, McBrayer SK, Qian J, Raikoff K, Avram MJ, Singhal S, Gandhi V, Schumacker PT, Krett NL, Rosen ST. Targeting glucose consumption and autophagy in myeloma with the novel nucleoside analogue 8-aminoadenosine. J Biol Chem. 2009 Sep 25; 284(39):26816-30. PMID: 19648108.
      Citations: 21     Fields:    Translation:HumansCells
    125. Stellrecht CM, Ayres M, Arya R, Gandhi V. A unique RNA-directed nucleoside analog is cytotoxic to breast cancer cells and depletes cyclin E levels. Breast Cancer Res Treat. 2010 Jun; 121(2):355-64. PMID: 19641990.
      Citations: 15     Fields:    Translation:HumansCells
    126. Pounds S, Cheng C, Cao X, Crews KR, Plunkett W, Gandhi V, Rubnitz J, Ribeiro RC, Downing JR, Lamba J. PROMISE: a tool to identify genomic features with a specific biologically interesting pattern of associations with multiple endpoint variables. Bioinformatics. 2009 Aug 15; 25(16):2013-9. PMID: 19528086.
      Citations: 9     Fields:    
    127. Quiroga MP, Balakrishnan K, Kurtova AV, Sivina M, Keating MJ, Wierda WG, Gandhi V, Burger JA. B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406. Blood. 2009 Jul 30; 114(5):1029-37. PMID: 19491390.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    128. Chen LS, Nowak BJ, Ayres ML, Krett NL, Rosen ST, Zhang S, Gandhi V. Inhibition of ATP synthase by chlorinated adenosine analogue. Biochem Pharmacol. 2009 Sep 15; 78(6):583-91. PMID: 19477165.
      Citations: 13     Fields:    Translation:Cells
    129. Stellrecht CM, Gandhi V. Myeloma antioxidant status: the good, the bad and the reactive. Leuk Lymphoma. 2009 May; 50(5):691-3. PMID: 19347768.
      Citations: 1     Fields:    Translation:Humans
    130. Cervantes-Gomez F, Nimmanapalli R, Gandhi V. Transcription inhibition of heat shock proteins: a strategy for combination of 17-allylamino-17-demethoxygeldanamycin and actinomycin d. Cancer Res. 2009 May 01; 69(9):3947-54. PMID: 19383903.
      Citations: 5     Fields:    Translation:HumansCells
    131. Rubnitz JE, Crews KR, Pounds S, Yang S, Campana D, Gandhi VV, Raimondi SC, Downing JR, Razzouk BI, Pui CH, Ribeiro RC. Combination of cladribine and cytarabine is effective for childhood acute myeloid leukemia: results of the St Jude AML97 trial. Leukemia. 2009 Aug; 23(8):1410-6. PMID: 19242495.
      Citations: 23     Fields:    Translation:Humans
    132. Guo Y, Köck K, Ritter CA, Chen ZS, Grube M, Jedlitschky G, Illmer T, Ayres M, Beck JF, Siegmund W, Ehninger G, Gandhi V, Kroemer HK, Kruh GD, Schaich M. Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival. Clin Cancer Res. 2009 Mar 01; 15(5):1762-9. PMID: 19240178.
      Citations: 28     Fields:    Translation:HumansCells
    133. Chen R, Wierda WG, Chubb S, Hawtin RE, Fox JA, Keating MJ, Gandhi V, Plunkett W. Mechanism of action of SNS-032, a novel cyclin-dependent kinase inhibitor, in chronic lymphocytic leukemia. Blood. 2009 May 07; 113(19):4637-45. PMID: 19234140.
      Citations: 66     Fields:    Translation:HumansCells
    134. Sampath D, Gandhi V. Dialing resistance up a Notch. Leuk Lymphoma. 2009 Feb; 50(2):158-9. PMID: 19235014.
      Citations:    Fields:    Translation:HumansCells
    135. Sánchez-Vega B, Gandhi V. Glucocorticoid resistance in a multiple myeloma cell line is regulated by a transcription elongation block in the glucocorticoid receptor gene (NR3C1). Br J Haematol. 2009 Mar; 144(6):856-64. PMID: 19133980.
      Citations: 7     Fields:    Translation:HumansCells
    136. Stellrecht CM, Gandhi V. MET receptor tyrosine kinase as a therapeutic anticancer target. Cancer Lett. 2009 Jul 18; 280(1):1-14. PMID: 19100682.
      Citations: 16     Fields:    Translation:HumansCells
    137. Borthakur G, Kantarjian H, Wang X, Plunkett WK, Gandhi VV, Faderl S, Garcia-Manero G, Ravandi F, Pierce S, Estey EH. Treatment of core-binding-factor in acute myelogenous leukemia with fludarabine, cytarabine, and granulocyte colony-stimulating factor results in improved event-free survival. Cancer. 2008 Dec 01; 113(11):3181-5. PMID: 18932257.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    138. Gandhi V, Balakrishnan K, Chen LS. Mcl-1: the 1 in CLL. Blood. 2008 Nov 01; 112(9):3538-40. PMID: 18948586.
      Citations: 15     Fields:    
    139. Balakrishnan K, Burger JA, Wierda WG, Gandhi V. AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance. Blood. 2009 Jan 01; 113(1):149-53. PMID: 18836097.
      Citations: 64     Fields:    Translation:HumansCells
    140. Balakrishnan K, Wierda WG, Keating MJ, Gandhi V. Gossypol, a BH3 mimetic, induces apoptosis in chronic lymphocytic leukemia cells. Blood. 2008 Sep 01; 112(5):1971-80. PMID: 18566329.
      Citations: 34     Fields:    Translation:HumansCells
    141. Phillip CJ, Stellrecht CM, Nimmanapalli R, Gandhi V. Targeting MET transcription as a therapeutic strategy in multiple myeloma. Cancer Chemother Pharmacol. 2009 Mar; 63(4):587-97. PMID: 18509644.
      Citations: 11     Fields:    Translation:HumansCells
    142. Nimmanapalli R, Gerbino E, Dalton WS, Gandhi V, Alsina M. HSP70 inhibition reverses cell adhesion mediated and acquired drug resistance in multiple myeloma. Br J Haematol. 2008 Aug; 142(4):551-61. PMID: 18503584.
      Citations: 19     Fields:    Translation:HumansCells
    143. Chen LS, Plunkett W, Gandhi V. Polyadenylation inhibition by the triphosphates of deoxyadenosine analogues. Leuk Res. 2008 Oct; 32(10):1573-81. PMID: 18433867.
      Citations: 4     Fields:    Translation:Cells
    144. Faderl S, Gandhi V, Kantarjian HM. Potential role of novel nucleoside analogs in the treatment of acute myeloid leukemia. Curr Opin Hematol. 2008 Mar; 15(2):101-7. PMID: 18300755.
      Citations: 4     Fields:    Translation:Humans
    145. Gandhi V, Tam C, O'Brien S, Jewell RC, Rodriguez CO, Lerner S, Plunkett W, Keating MJ. Phase I trial of nelarabine in indolent leukemias. J Clin Oncol. 2008 Mar 01; 26(7):1098-105. PMID: 18309944.
      Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
    146. Chen LS, Stellrecht CM, Gandhi V. RNA-directed agent, cordycepin, induces cell death in multiple myeloma cells. Br J Haematol. 2008 Mar; 140(6):682-391. PMID: 18205859.
      Citations: 22     Fields:    Translation:HumansCells
    147. Gandhi V. Questions about gemcitabine dose rate: answered or unanswered? J Clin Oncol. 2007 Dec 20; 25(36):5691-4. PMID: 18089862.
      Citations: 4     Fields:    Translation:Humans
    148. Gandhi V, Balakrishnan K. Pharmacology and mechanism of action of forodesine, a T-cell targeted agent. Semin Oncol. 2007 Dec; 34(6 Suppl 5):S8-12. PMID: 18086347.
      Citations: 11     Fields:    Translation:HumansCells
    149. Stellrecht CM, Phillip CJ, Cervantes-Gomez F, Gandhi V. Multiple myeloma cell killing by depletion of the MET receptor tyrosine kinase. Cancer Res. 2007 Oct 15; 67(20):9913-20. PMID: 17942923.
      Citations: 20     Fields:    Translation:Humans
    150. Tili E, Michaille JJ, Gandhi V, Plunkett W, Sampath D, Calin GA. miRNAs and their potential for use against cancer and other diseases. Future Oncol. 2007 Oct; 3(5):521-37. PMID: 17927518.
      Citations: 42     Fields:    Translation:HumansAnimals
    151. Kantarjian HM, Jeha S, Gandhi V, Wess M, Faderl S. Clofarabine: past, present, and future. Leuk Lymphoma. 2007 Oct; 48(10):1922-30. PMID: 17852710.
      Citations: 21     Fields:    Translation:HumansAnimals
    152. Lamba JK, Crews K, Pounds S, Schuetz EG, Gresham J, Gandhi V, Plunkett W, Rubnitz J, Ribeiro R. Pharmacogenetics of deoxycytidine kinase: identification and characterization of novel genetic variants. J Pharmacol Exp Ther. 2007 Dec; 323(3):935-45. PMID: 17855478.
      Citations: 39     Fields:    Translation:HumansCells
    153. Flanagan SA, Gandhi V, Meckling KA. Guanosine acts intracellularly to initiate apoptosis in NB4 cells: A role for nucleoside transport. Leuk Lymphoma. 2007 Sep; 48(9):1816-27. PMID: 17786719.
      Citations: 3     Fields:    Translation:HumansCells
    154. Karp JE, Ricklis RM, Balakrishnan K, Briel J, Greer J, Gore SD, Smith BD, McDevitt MA, Carraway H, Levis MJ, Gandhi V. A phase 1 clinical-laboratory study of clofarabine followed by cyclophosphamide for adults with refractory acute leukemias. Blood. 2007 Sep 15; 110(6):1762-9. PMID: 17562873.
      Citations: 27     Fields:    Translation:HumansCellsCTClinical Trials
    155. Gandhi V. p53 as a predictor for chemotherapy response in CLL cells. Leuk Lymphoma. 2007 Feb; 48(2):219-20. PMID: 17325877.
      Citations: 1     Fields:    Translation:Humans
    156. Ravandi F, Gandhi V. Novel purine nucleoside analogues for T-cell-lineage acute lymphoblastic leukaemia and lymphoma. Expert Opin Investig Drugs. 2006 Dec; 15(12):1601-13. PMID: 17107284.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    157. Sánchez-Vega B, Krett N, Rosen ST, Gandhi V. Glucocorticoid receptor transcriptional isoforms and resistance in multiple myeloma cells. Mol Cancer Ther. 2006 Dec; 5(12):3062-70. PMID: 17172408.
      Citations: 13     Translation:HumansCells
    158. Nimmanapalli R, Lyu MA, Du M, Keating MJ, Rosenblum MG, Gandhi V. The growth factor fusion construct containing B-lymphocyte stimulator (BLyS) and the toxin rGel induces apoptosis specifically in BAFF-R-positive CLL cells. Blood. 2007 Mar 15; 109(6):2557-64. PMID: 17119117.
      Citations: 13     Fields:    Translation:HumansCells
    159. Chen R, Gandhi V, Plunkett W. A sequential blockade strategy for the design of combination therapies to overcome oncogene addiction in chronic myelogenous leukemia. Cancer Res. 2006 Nov 15; 66(22):10959-66. PMID: 17108134.
      Citations: 29     Fields:    Translation:HumansCells
    160. Gandhi V, Plunkett W. Clofarabine and nelarabine: two new purine nucleoside analogs. Curr Opin Oncol. 2006 Nov; 18(6):584-90. PMID: 16988579.
      Citations: 12     Fields:    Translation:Humans
    161. Gandhi V, Plunkett W, Bonate PL, Du M, Nowak B, Lerner S, Keating MJ. Clinical and pharmacokinetic study of clofarabine in chronic lymphocytic leukemia: strategy for treatment. Clin Cancer Res. 2006 Jul 01; 12(13):4011-7. PMID: 16818700.
      Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
    162. Chandra D, Bratton SB, Person MD, Tian Y, Martin AG, Ayres M, Fearnhead HO, Gandhi V, Tang DG. Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome. Cell. 2006 Jun 30; 125(7):1333-46. PMID: 16814719.
      Citations: 52     Fields:    Translation:HumansCells
    163. Balakrishnan K, Nimmanapalli R, Ravandi F, Keating MJ, Gandhi V. Forodesine, an inhibitor of purine nucleoside phosphorylase, induces apoptosis in chronic lymphocytic leukemia cells. Blood. 2006 Oct 01; 108(7):2392-8. PMID: 16778146.
      Citations: 22     Fields:    Translation:HumansCells
    164. Mehta K, Gandhi V, Aggarwal BB. All pathways to cancer apoptosis meeting in Thiruvananthapuram (India). Cell Death Differ. 2006 Dec; 13(12):2163-4. PMID: 16741526.
      Citations:    Fields:    Translation:HumansAnimalsCells
    165. Gandhi V, Keating MJ, Bate G, Kirkpatrick P. Nelarabine. Nat Rev Drug Discov. 2006 Jan; 5(1):17-8. PMID: 16485343.
      Citations: 7     Fields:    Translation:HumansCells
    166. Sampath D, Cortes J, Estrov Z, Du M, Shi Z, Andreeff M, Gandhi V, Plunkett W. Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial. Blood. 2006 Mar 15; 107(6):2517-24. PMID: 16293603.
      Citations: 44     Fields:    Translation:HumansCellsCTClinical Trials
    167. Balakrishnan K, Wierda WG, Keating MJ, Gandhi V. Mechanisms of cell death of chronic lymphocytic leukemia lymphocytes by RNA-directed agent, 8-NH2-adenosine. Clin Cancer Res. 2005 Sep 15; 11(18):6745-52. PMID: 16166456.
      Citations: 9     Fields:    Translation:HumansCells
    168. Gandhi V, Kilpatrick JM, Plunkett W, Ayres M, Harman L, Du M, Bantia S, Davisson J, Wierda WG, Faderl S, Kantarjian H, Thomas D. A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine). Blood. 2005 Dec 15; 106(13):4253-60. PMID: 16131572.
      Citations: 26     Fields:    Translation:HumansCellsCTClinical Trials
    169. Jabbour E, Verstovsek S, Giles F, Gandhi V, Cortes J, O'Brien S, Plunkett W, Garcia-Manero G, Jackson CE, Kantarjian H, Andreeff M. 2-Chlorodeoxyadenosine and cytarabine combination therapy for idiopathic hypereosinophilic syndrome. Cancer. 2005 Aug 01; 104(3):541-6. PMID: 15977212.
      Citations: 4     Fields:    Translation:Humans
    170. Chen R, Keating MJ, Gandhi V, Plunkett W. Transcription inhibition by flavopiridol: mechanism of chronic lymphocytic leukemia cell death. Blood. 2005 Oct 01; 106(7):2513-9. PMID: 15972445.
      Citations: 99     Fields:    Translation:HumansCells
    171. Kurtzberg J, Ernst TJ, Keating MJ, Gandhi V, Hodge JP, Kisor DF, Lager JJ, Stephens C, Levin J, Krenitsky T, Elion G, Mitchell BS. Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies. J Clin Oncol. 2005 May 20; 23(15):3396-403. PMID: 15908652.
      Citations: 32     Fields:    Translation:HumansCTClinical Trials
    172. Faderl S, Gandhi V, Keating MJ, Jeha S, Plunkett W, Kantarjian HM. The role of clofarabine in hematologic and solid malignancies--development of a next-generation nucleoside analog. Cancer. 2005 May 15; 103(10):1985-95. PMID: 15803490.
      Citations: 20     Fields:    Translation:Humans
    173. Ghias K, Ma C, Gandhi V, Platanias LC, Krett NL, Rosen ST. 8-Amino-adenosine induces loss of phosphorylation of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase 1/2, and Akt kinase: role in induction of apoptosis in multiple myeloma. Mol Cancer Ther. 2005 Apr; 4(4):569-77. PMID: 15827330.
      Citations: 15     Translation:HumansCells
    174. Balakrishnan K, Stellrecht CM, Genini D, Ayres M, Wierda WG, Keating MJ, Leoni LM, Gandhi V. Cell death of bioenergetically compromised and transcriptionally challenged CLL lymphocytes by chlorinated ATP. Blood. 2005 Jun 01; 105(11):4455-62. PMID: 15718423.
      Citations: 24     Fields:    Translation:HumansCells
    175. Bonate PL, Craig A, Gaynon P, Gandhi V, Jeha S, Kadota R, Lam GN, Plunkett W, Razzouk B, Rytting M, Steinherz P, Weitman S. Population pharmacokinetics of clofarabine, a second-generation nucleoside analog, in pediatric patients with acute leukemia. J Clin Pharmacol. 2004 Nov; 44(11):1309-22. PMID: 15496649.
      Citations: 9     Fields:    Translation:Humans
    176. Krett NL, Davies KM, Ayres M, Ma C, Nabhan C, Gandhi V, Rosen ST. 8-amino-adenosine is a potential therapeutic agent for multiple myeloma. Mol Cancer Ther. 2004 Nov; 3(11):1411-20. PMID: 15542780.
      Citations: 15     Translation:HumansCells
    177. Cooper T, Ayres M, Nowak B, Gandhi V. Biochemical modulation of cytarabine triphosphate by clofarabine. Cancer Chemother Pharmacol. 2005 Apr; 55(4):361-368. PMID: 15723262.
      Citations: 25     Fields:    Translation:HumansCells
    178. Faderl S, Gandhi V, O'Brien S, Bonate P, Cortes J, Estey E, Beran M, Wierda W, Garcia-Manero G, Ferrajoli A, Estrov Z, Giles FJ, Du M, Kwari M, Keating M, Plunkett W, Kantarjian H. Results of a phase 1-2 study of clofarabine in combination with cytarabine (ara-C) in relapsed and refractory acute leukemias. Blood. 2005 Feb 01; 105(3):940-7. PMID: 15486072.
      Citations: 52     Fields:    Translation:HumansCTClinical Trials
    179. Cooper T, Kantarjian H, Plunkett W, Gandhi V. Clofarabine in adult acute leukemias: clinical success and pharmacokinetics. Nucleosides Nucleotides Nucleic Acids. 2004 Oct; 23(8-9):1417-23. PMID: 15571270.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    180. Krett NL, Ayres M, Nabhan C, Ma C, Nowak B, Nawrocki S, Rosen ST, Gandhi V. In vitro assessment of nucleoside analogs in multiple myeloma. Cancer Chemother Pharmacol. 2004 Aug; 54(2):113-21. PMID: 15133625.
      Citations: 3     Fields:    Translation:HumansCells
    181. Gandhi V, Kantarjian H, Faderl S, Bonate P, Du M, Ayres M, Rios MB, Keating MJ, Plunkett W. Pharmacokinetics and pharmacodynamics of plasma clofarabine and cellular clofarabine triphosphate in patients with acute leukemias. Clin Cancer Res. 2003 Dec 15; 9(17):6335-42. PMID: 14695132.
      Citations: 17     Fields:    Translation:HumansCellsCTClinical Trials
    182. Giles FJ, Fracasso PM, Kantarjian HM, Cortes JE, Brown RA, Verstovsek S, Alvarado Y, Thomas DA, Faderl S, Garcia-Manero G, Wright LP, Samson T, Cahill A, Lambert P, Plunkett W, Sznol M, DiPersio JF, Gandhi V. Phase I and pharmacodynamic study of Triapine, a novel ribonucleotide reductase inhibitor, in patients with advanced leukemia. Leuk Res. 2003 Dec; 27(12):1077-83. PMID: 12921943.
      Citations: 26     Fields:    Translation:HumansCTClinical Trials
    183. Stellrecht CM, Rodriguez CO, Ayres M, Gandhi V. RNA-directed actions of 8-chloro-adenosine in multiple myeloma cells. Cancer Res. 2003 Nov 15; 63(22):7968-74. PMID: 14633728.
      Citations: 24     Fields:    Translation:HumansCells
    184. Jeha S, Gandhi V, Chan KW, McDonald L, Ramirez I, Madden R, Rytting M, Brandt M, Keating M, Plunkett W, Kantarjian H. Clofarabine, a novel nucleoside analog, is active in pediatric patients with advanced leukemia. Blood. 2004 Feb 01; 103(3):784-9. PMID: 14551141.
      Citations: 62     Fields:    Translation:HumansCTClinical Trials
    185. Flanagan SA, Gandhi V, Secrist JA, Meckling KA. The novel nucleoside transport system exhibited by NB4 cells, csg, transports deoxyguanosine analogues, including ara-G. Biochem Pharmacol. 2003 Sep 01; 66(5):733-7. PMID: 12948853.
      Citations: 1     Fields:    Translation:HumansCells
    186. Kantarjian H, Gandhi V, Cortes J, Verstovsek S, Du M, Garcia-Manero G, Giles F, Faderl S, O'Brien S, Jeha S, Davis J, Shaked Z, Craig A, Keating M, Plunkett W, Freireich EJ. Phase 2 clinical and pharmacologic study of clofarabine in patients with refractory or relapsed acute leukemia. Blood. 2003 Oct 01; 102(7):2379-86. PMID: 12791647.
      Citations: 70     Fields:    Translation:HumansCTClinical Trials
    187. Rodriguez CO, Stellrecht CM, Gandhi V. Mechanisms for T-cell selective cytotoxicity of arabinosylguanine. Blood. 2003 Sep 01; 102(5):1842-8. PMID: 12750168.
      Citations: 23     Fields:    Translation:HumansCells
    188. Wright K, Popli S, Gandhi VC, Lentino JR, Reyes CV, Leehey DJ. Paecilomyces peritonitis: case report and review of the literature. Clin Nephrol. 2003 Apr; 59(4):305-10. PMID: 12708573.
      Citations: 3     Fields:    Translation:HumansAnimals
    189. Kantarjian HM, Gandhi V, Kozuch P, Faderl S, Giles F, Cortes J, O'Brien S, Ibrahim N, Khuri F, Du M, Rios MB, Jeha S, McLaughlin P, Plunkett W, Keating M. Phase I clinical and pharmacology study of clofarabine in patients with solid and hematologic cancers. J Clin Oncol. 2003 Mar 15; 21(6):1167-73. PMID: 12637486.
      Citations: 42     Fields:    Translation:HumansCTClinical Trials
    190. Sharma GG, Gupta A, Wang H, Scherthan H, Dhar S, Gandhi V, Iliakis G, Shay JW, Young CS, Pandita TK. hTERT associates with human telomeres and enhances genomic stability and DNA repair. Oncogene. 2003 Jan 09; 22(1):131-46. PMID: 12527915.
      Citations: 75     Fields:    Translation:HumansCells
    191. Nabhan C, Gajria D, Krett NL, Gandhi V, Ghias K, Rosen ST. Caspase activation is required for gemcitabine activity in multiple myeloma cell lines. Mol Cancer Ther. 2002 Nov; 1(13):1221-7. PMID: 12479703.
      Citations: 9     Translation:HumansCells
    192. Stellrecht CM, Gandhi V. Concurrent isolation of ribosomal, messenger, and low molecular weight RNA. Biotechniques. 2002 Nov; 33(5):1122-4. PMID: 12449393.
      Citations:    Fields:    Translation:HumansCells
    193. Crews KR, Gandhi V, Srivastava DK, Razzouk BI, Tong X, Behm FG, Plunkett W, Raimondi SC, Pui CH, Rubnitz JE, Stewart CF, Ribeiro RC. Interim comparison of a continuous infusion versus a short daily infusion of cytarabine given in combination with cladribine for pediatric acute myeloid leukemia. J Clin Oncol. 2002 Oct 15; 20(20):4217-24. PMID: 12377965.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    194. Gandhi V. Metabolism and mechanisms of action of bendamustine: rationales for combination therapies. Semin Oncol. 2002 Aug; 29(4 Suppl 13):4-11. PMID: 12170425.
      Citations: 29     Fields:    Translation:HumansCells
    195. Gandhi V, Chen W, Ayres M, Rhie JK, Madden TL, Newman RA. Plasma and cellular pharmacology of 8-chloro-adenosine in mice and rats. Cancer Chemother Pharmacol. 2002 Aug; 50(2):85-94. PMID: 12172971.
      Citations: 7     Fields:    Translation:AnimalsCells
    196. Rodriguez CO, Mitchell BS, Ayres M, Eriksson S, Gandhi V. Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. Cancer Res. 2002 Jun 01; 62(11):3100-5. PMID: 12036920.
      Citations: 17     Fields:    Translation:HumansCells
    197. Lin-Lee YC, Nakamura S, Gandhi V, Curley SA, Stüber D, Burkot TR, Kuo MT. Prolonged stability and sustained prodrug cell killing activity using receptor-mediated delivery of malarial circumsporozoite-cytosine deaminase fusion protein into liver cancer cells. Mol Cancer Ther. 2002 May; 1(7):461-7. PMID: 12479264.
      Citations: 1     Translation:HumansCells
    198. Gandhi V, Plunkett W, Du M, Ayres M, Estey EH. Prolonged infusion of gemcitabine: clinical and pharmacodynamic studies during a phase I trial in relapsed acute myelogenous leukemia. J Clin Oncol. 2002 Feb 01; 20(3):665-73. PMID: 11821446.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    199. Faderl S, Gandhi V, Kantarjian H, Plunkett W. New nucleoside analogues in clinical development. Cancer Chemother Biol Response Modif. 2002; 20:37-58. PMID: 12703199.
      Citations: 1     Fields:    Translation:HumansAnimals
    200. Gandhi V, Plunkett W. Cellular and clinical pharmacology of fludarabine. Clin Pharmacokinet. 2002; 41(2):93-103. PMID: 11888330.
      Citations: 63     Fields:    Translation:HumansCells
    201. Zhou Y, Achanta G, Pelicano H, Gandhi V, Plunkett W, Huang P. Action of (E)-2'-deoxy-2'-(fluoromethylene)cytidine on DNA metabolism: incorporation, excision, and cellular response. Mol Pharmacol. 2002 Jan; 61(1):222-9. PMID: 11752224.
      Citations: 5     Fields:    Translation:HumansCells
    202. Nabhan C, Krett N, Gandhi V, Rosen S. Gemcitabine in hematologic malignancies. Curr Opin Oncol. 2001 Nov; 13(6):514-21. PMID: 11673693.
      Citations: 7     Fields:    Translation:HumansCells
    203. Patel SR, Gandhi V, Jenkins J, Papadopolous N, Burgess MA, Plager C, Plunkett W, Benjamin RS. Phase II clinical investigation of gemcitabine in advanced soft tissue sarcomas and window evaluation of dose rate on gemcitabine triphosphate accumulation. J Clin Oncol. 2001 Aug 01; 19(15):3483-9. PMID: 11481354.
      Citations: 62     Fields:    Translation:HumansCellsCTClinical Trials
    204. Gandhi V, Ayres M, Halgren RG, Krett NL, Newman RA, Rosen ST. 8-chloro-cAMP and 8-chloro-adenosine act by the same mechanism in multiple myeloma cells. Cancer Res. 2001 Jul 15; 61(14):5474-9. PMID: 11454694.
      Citations: 35     Fields:    Translation:HumansCells
    205. Gandhi V, Plunkett W, Weller S, Du M, Ayres M, Rodriguez CO, Ramakrishna P, Rosner GL, Hodge JP, O'Brien S, Keating MJ. Evaluation of the combination of nelarabine and fludarabine in leukemias: clinical response, pharmacokinetics, and pharmacodynamics in leukemia cells. J Clin Oncol. 2001 Apr 15; 19(8):2142-52. PMID: 11304766.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    206. Plunkett W, Gandhi V. Purine and pyrimidine nucleoside analogs. Cancer Chemother Biol Response Modif. 2001; 19:21-45. PMID: 11686015.
      Citations: 15     Fields:    Translation:HumansAnimals
    207. Boorgu R, Dubrow AJ, Levin NW, My H, Canaud BJ, Lentino JR, Wentworth DW, Hatch DA, Megerman J, Prosl FR, Gandhi VC, Ing TS. Adjunctive antibiotic/anticoagulant lock therapy in the treatment of bacteremia associated with the use of a subcutaneously implanted hemodialysis access device. ASAIO J. 2000 Nov-Dec; 46(6):767-70. PMID: 11110278.
      Citations: 4     Fields:    Translation:Humans
    208. Rodriguez CO, Plunkett W, Paff MT, Du M, Nowak B, Ramakrishna P, Keating MJ, Gandhi V. High-performance liquid chromatography method for the determination and quantitation of arabinosylguanine triphosphate and fludarabine triphosphate in human cells. J Chromatogr B Biomed Sci Appl. 2000 Aug 18; 745(2):421-30. PMID: 11043760.
      Citations: 7     Fields:    Translation:HumansCells
    209. Kisor DF, Plunkett W, Kurtzberg J, Mitchell B, Hodge JP, Ernst T, Keating MJ, Gandhi V. Pharmacokinetics of nelarabine and 9-beta-D-arabinofuranosyl guanine in pediatric and adult patients during a phase I study of nelarabine for the treatment of refractory hematologic malignancies. J Clin Oncol. 2000 Mar; 18(5):995-1003. PMID: 10694549.
      Citations: 13     Fields:    Translation:HumansCTClinical Trials
    210. Giles FJ, O'Brien SM, Santini V, Gandhi V, Plunkett W, Seymour JF, Robertson LE, Kantarjian HM, Keating MJ. Sequential cis-platinum and fludarabine with or without arabinosyl cytosine in patients failing prior fludarabine therapy for chronic lymphocytic leukemia: a phase II study. Leuk Lymphoma. 1999 Dec; 36(1-2):57-65. PMID: 10613450.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    211. Rodriguez CO, Gandhi V. Arabinosylguanine-induced apoptosis of T-lymphoblastic cells: incorporation into DNA is a necessary step. Cancer Res. 1999 Oct 01; 59(19):4937-43. PMID: 10519407.
      Citations: 13     Fields:    Translation:HumansCells
    212. Dumontet C, Fabianowska-Majewska K, Mantincic D, Callet Bauchu E, Tigaud I, Gandhi V, Lepoivre M, Peters GJ, Rolland MO, Wyczechowska D, Fang X, Gazzo S, Voorn DA, Vanier-Viornery A, MacKey J. Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562. Br J Haematol. 1999 Jul; 106(1):78-85. PMID: 10444166.
      Citations: 28     Fields:    Translation:HumansCells
    213. Aguayo A, Cortes JE, Kantarjian HM, Beran M, Gandhi V, Plunkett W, Kurtzberg J, Keating MJ. Complete hematologic and cytogenetic response to 2-amino-9-beta-D-arabinosyl-6-methoxy-9H-guanine in a patient with chronic myelogenous leukemia in T-cell blastic phase: a case report and review of the literature. Cancer. 1999 Jan 01; 85(1):58-64. PMID: 9921974.
      Citations: 4     Fields:    Translation:HumansCells
    214. Gandhi V, Plunkett W, Rodriguez CO, Nowak BJ, Du M, Ayres M, Kisor DF, Mitchell BS, Kurtzberg J, Keating MJ. Compound GW506U78 in refractory hematologic malignancies: relationship between cellular pharmacokinetics and clinical response. J Clin Oncol. 1998 Nov; 16(11):3607-15. PMID: 9817282.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    215. Levin NW, Yang PM, Hatch DA, Dubrow AJ, Caraiani NS, Ing TS, Gandhi VC, Alto A, Davila SM, Prosl FR, Polaschegg HD, Megerman J. Initial results of a new access device for hemodialysis technical note. Kidney Int. 1998 Nov; 54(5):1739-45. PMID: 9844153.
      Citations: 3     Fields:    Translation:Humans
    216. Levin NW, Yang PM, Hatch DA, Dubrow AJ, Caraiani NS, Ing TS, Gandhi VC, Alto A, Davila SM, Prosl FR, Polaschegg HD, Megerman J. New access device for hemodialysis. ASAIO J. 1998 Sep-Oct; 44(5):M529-31. PMID: 9804487.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    217. Emelife-Obi C, Chow MT, Qamar-Rohail H, Leehey DJ, Gandhi VC, Ing TS. Use of a phosphorus-enriched hemodialysate to prevent hypophosphatemia in a patient with renal failure-related pericarditis. Clin Nephrol. 1998 Aug; 50(2):131-3. PMID: 9725787.
      Citations:    Fields:    Translation:Humans
    218. Gandhi V, Plunkett W, Kantarjian H, Talpaz M, Robertson LE, O'Brien S. Cellular pharmacodynamics and plasma pharmacokinetics of parenterally infused hydroxyurea during a phase I clinical trial in chronic myelogenous leukemia. J Clin Oncol. 1998 Jul; 16(7):2321-31. PMID: 9667246.
      Citations: 10     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    219. Gandhi V, Xu YZ, Estey E. Accumulation of arabinosyluracil 5'-triphosphate during arabinosylcytosine therapy in circulating blasts of patients with acute myelogenous leukemia. Clin Cancer Res. 1998 Jul; 4(7):1719-26. PMID: 9676847.
      Citations: 3     Fields:    Translation:Humans
    220. Rodriguez CO, Legha JK, Estey E, Keating MJ, Gandhi V. Pharmacological and biochemical strategies to increase the accumulation of arabinofuranosylguanine triphosphatein primary human leukemia cells. Clin Cancer Res. 1997 Nov; 3(11):2107-13. PMID: 9815603.
      Citations: 4     Fields:    Translation:Humans
    221. Gandhi V, Estey E, Du M, Keating MJ, Plunkett W. Minimum dose of fludarabine for the maximal modulation of 1-beta-D-arabinofuranosylcytosine triphosphate in human leukemia blasts during therapy. Clin Cancer Res. 1997 Sep; 3(9):1539-45. PMID: 9815841.
      Citations: 12     Fields:    Translation:HumansCells
    222. Gandhi V, Huang P, Chapman AJ, Chen F, Plunkett W. Incorporation of fludarabine and 1-beta-D-arabinofuranosylcytosine 5'-triphosphates by DNA polymerase alpha: affinity, interaction, and consequences. Clin Cancer Res. 1997 Aug; 3(8):1347-55. PMID: 9815818.
      Citations: 8     Fields:    Translation:HumansCells
    223. Plunkett W, Gandhi V. Pharmacology of purine nucleoside analogues. Hematol Cell Ther. 1996 Dec; 38 Suppl 2:S67-74. PMID: 9137959.
      Citations: 2     Fields:    Translation:HumansAnimals
    224. Keating MJ, O'Brien S, McLaughlin P, Dimopoulos M, Gandhi V, Plunkett W, Lerner S, Kantarjian H, Estey E. Clinical experience with fludarabine in hemato-oncology. Hematol Cell Ther. 1996 Dec; 38 Suppl 2:S83-91. PMID: 9137961.
      Citations: 3     Fields:    Translation:Humans
    225. Gandhi V, Legha J, Chen F, Hertel LW, Plunkett W. Excision of 2',2'-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA. Cancer Res. 1996 Oct 01; 56(19):4453-9. PMID: 8813140.
      Citations: 18     Fields:    
    226. Plunkett W, Huang P, Searcy CE, Gandhi V. Gemcitabine: preclinical pharmacology and mechanisms of action. Semin Oncol. 1996 Oct; 23(5 Suppl 10):3-15. PMID: 8893876.
      Citations: 82     Fields:    Translation:HumansAnimals
    227. Kornblau SM, Gandhi V, Andreeff HM, Beran M, Kantarjian HM, Koller CA, O'Brien S, Plunkett W, Estey E. Clinical and laboratory studies of 2-chlorodeoxyadenosine +/- cytosine arabinoside for relapsed or refractory acute myelogenous leukemia in adults. Leukemia. 1996 Oct; 10(10):1563-9. PMID: 8847890.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    228. Gandhi V, Estey EH, Keating MJ, Plunkett W. Intracellular pharmacodynamics in leukemia therapy. Rinsho Ketsueki. 1996 May; 37(5):369-79. PMID: 8691580.
      Citations:    Fields:    Translation:Humans
    229. Seymour JF, Huang P, Plunkett W, Gandhi V. Influence of fludarabine on pharmacokinetics and pharmacodynamics of cytarabine: implications for a continuous infusion schedule. Clin Cancer Res. 1996 Apr; 2(4):653-8. PMID: 9816215.
      Citations: 12     Fields:    Translation:HumansCells
    230. Loughlin S, Gandhi V, Plunkett W, Zwelling LA. The effect of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 1-beta-D-arabinofuranosylcytosine on the cell cycle phase distribution, topoisomerase II level, mitoxantrone cytotoxicity, and DNA strand break production in K562 human leukemia cells. Cancer Chemother Pharmacol. 1996; 38(3):261-8. PMID: 8646801.
      Citations:    Fields:    Translation:HumansCells
    231. Gandhi V, Estey E, Keating MJ, Chucrallah A, Plunkett W. Chlorodeoxyadenosine and arabinosylcytosine in patients with acute myelogenous leukemia: pharmacokinetic, pharmacodynamic, and molecular interactions. Blood. 1996 Jan 01; 87(1):256-64. PMID: 8547650.
      Citations: 24     Fields:    Translation:HumansCellsCTClinical Trials
    232. Plunkett W, Huang P, Gandhi V. Preclinical characteristics of gemcitabine. Anticancer Drugs. 1995 Dec; 6 Suppl 6:7-13. PMID: 8718419.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    233. Plunkett W, Huang P, Xu YZ, Heinemann V, Grunewald R, Gandhi V. Gemcitabine: metabolism, mechanisms of action, and self-potentiation. Semin Oncol. 1995 Aug; 22(4 Suppl 11):3-10. PMID: 7481842.
      Citations: 174     Fields:    Translation:HumansAnimalsCells
    234. Gandhi V, Mineishi S, Huang P, Yang Y, Chubb S, Chapman AJ, Nowak BJ, Hertel LW, Plunkett W. Difluorodeoxyguanosine: cytotoxicity, metabolism, and actions on DNA synthesis in human leukemia cells. Semin Oncol. 1995 Aug; 22(4 Suppl 11):61-7. PMID: 7481847.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    235. Ejaz AA, Nisar N, Gandhi VC, Eilers DB, Shirazi PH, Ing TS. Metastatic soft tissue calcification in chronic renal failure detected by radionuclide imaging. Clin Nucl Med. 1995 Jun; 20(6):505-7. PMID: 7648732.
      Citations:    Fields:    Translation:Humans
    236. Gandhi V, Mineishi S, Huang P, Chapman AJ, Yang Y, Chen F, Nowak B, Chubb S, Hertel LW, Plunkett W. Cytotoxicity, metabolism, and mechanisms of action of 2',2'-difluorodeoxyguanosine in Chinese hamster ovary cells. Cancer Res. 1995 Apr 01; 55(7):1517-24. PMID: 7533664.
      Citations: 7     Fields:    Translation:AnimalsCells
    237. Gandhi V, Estey E, Du M, Nowak B, Keating MJ, Plunkett W. Modulation of the cellular metabolism of cytarabine and fludarabine by granulocyte-colony-stimulating factor during therapy of acute myelogenous leukemia. Clin Cancer Res. 1995 Feb; 1(2):169-78. PMID: 9815970.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    238. Ejaz AA, McShane AP, Gandhi VC, Leehey DJ, Ing TS. Hypomagnesemia in continuous ambulatory peritoneal dialysis patients dialyzed with a low-magnesium peritoneal dialysis solution. Perit Dial Int. 1995; 15(1):61-4. PMID: 7734563.
      Citations: 11     Fields:    Translation:Humans
    239. Ing TS, Yu AW, Agrawal B, Tiwari PK, McShane AP, Kuna PP, Gandhi VC. Continuous ambulatory peritoneal dialysis using self-made, ultrafiltration-sterilized, L-lactate-based dialysis solution. Int J Artif Organs. 1994 Sep; 17(9):488-91. PMID: 7890437.
      Citations:    Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    240. Gandhi V, Du M, Kantarjian HM, Plunkett W. Effect of granulocyte-macrophage colony-stimulating factor on the metabolism of arabinosylcytosine triphosphate in blasts during therapy of patients with chronic myelogenous leukemia. Leukemia. 1994 Sep; 8(9):1463-8. PMID: 8090026.
      Citations:    Fields:    Translation:HumansCells
    241. Yu AW, Olabi AZ, Gupta DK, Zhou FQ, Gandhi VC, Ing TS. Effects of euhydric peritoneal dialysis solutions containing mixture of bicarbonate and lactate or lactate alone on neutrophilic superoxide production. ASAIO J. 1994 Jul-Sep; 40(3):M900-1. PMID: 8555643.
      Citations:    Fields:    Translation:HumansCells
    242. Ing TS, Yu AW, Nagaraja V, Amin NA, Ayache S, Gandhi VC, Daugirdas JT. Employing L-lactic acid powder in the preparation of a dry "acid concentrate" for use in a bicarbonate-based dialysis solution-generating system: experience in hemodialysis patients. Int J Artif Organs. 1994 Feb; 17(2):70-3. PMID: 8039942.
      Citations:    Fields:    Translation:Humans
    243. Plunkett W, Gandhi V. Evolution of the arabinosides and the pharmacology of fludarabine. Drugs. 1994; 47 Suppl 6:30-8. PMID: 7525187.
      Citations: 1     Fields:    Translation:HumansAnimals
    244. Gandhi V, Huang P, Plunkett W. Fludarabine inhibits DNA replication: a rationale for its use in the treatment of acute leukemias. Leuk Lymphoma. 1994; 14 Suppl 2:3-9. PMID: 7881348.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    245. Gandhi V, Estey E, Plunkett W. Modulation of arabinosylcytosine metabolism during leukemia therapy. Adv Exp Med Biol. 1994; 370:119-24. PMID: 7544948.
      Citations: 2     Fields:    Translation:Humans
    246. Keating MJ, O'Brien S, Plunkett W, Robertson LE, Gandhi V, Estey E, Dimopoulos M, Cabanillas F, Kemena A, Kantarjian H. Fludarabine phosphate: a new active agent in hematologic malignancies. Semin Hematol. 1994 Jan; 31(1):28-39. PMID: 7510070.
      Citations: 2     Fields:    Translation:HumansAnimals
    247. Keating MJ, McLaughlin P, Plunkett W, Robertson LE, O'Brien S, Gandhi V, Gregoire V, Yang L, Cabanillas F. Fludarabine--present status and future developments in chronic lymphocytic leukemia and lymphoma. Ann Oncol. 1994; 5 Suppl 2:79-83. PMID: 8204523.
      Citations: 1     Fields:    Translation:HumansCells
    248. Gandhi V, Robertson LE, Keating MJ, Plunkett W. Combination of fludarabine and arabinosylcytosine for treatment of chronic lymphocytic leukemia: clinical efficacy and modulation of arabinosylcytosine pharmacology. Cancer Chemother Pharmacol. 1994; 34(1):30-6. PMID: 8174200.
      Citations: 3     Fields:    Translation:Humans
    249. Keating MJ, O'Brien S, Robertson LE, Kantarjian H, Dimopoulos M, McLaughlin P, Cabanillas F, Gregoire V, Li YY, Gandhi V, et al. The expanding role of fludarabine in hematologic malignancies. Leuk Lymphoma. 1994; 14 Suppl 2:11-6. PMID: 7533576.
      Citations: 2     Fields:    Translation:Humans
    250. Plunkett W, Gandhi V, Huang P, Robertson LE, Yang LY, Gregoire V, Estey E, Keating MJ. Fludarabine: pharmacokinetics, mechanisms of action, and rationales for combination therapies. Semin Oncol. 1993 Oct; 20(5 Suppl 7):2-12. PMID: 8235690.
      Citations: 28     Fields:    Translation:Humans
    251. Keating MJ, O'Brien S, Robertson LE, Kantarjian H, Dimopoulos M, McLaughlin P, Cabanillas F, Gregoire V, Yang LY, Gandhi V, et al. New initiatives with fludarabine monophosphate in hematologic malignancies. Semin Oncol. 1993 Oct; 20(5 Suppl 7):13-20. PMID: 7694371.
      Citations: 1     Fields:    Translation:Humans
    252. Suki S, Kantarjian H, Gandhi V, Estey E, O'Brien S, Beran M, Rios MB, Plunkett W, Keating M. Fludarabine and cytosine arabinoside in the treatment of refractory or relapsed acute lymphocytic leukemia. Cancer. 1993 Oct 01; 72(7):2155-60. PMID: 8374873.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    253. Gandhi V, Kemena A, Keating MJ, Plunkett W. Cellular pharmacology of fludarabine triphosphate in chronic lymphocytic leukemia cells during fludarabine therapy. Leuk Lymphoma. 1993 May; 10(1-2):49-56. PMID: 8374523.
      Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
    254. Estey E, Plunkett W, Gandhi V, Rios MB, Kantarjian H, Keating MJ. Fludarabine and arabinosylcytosine therapy of refractory and relapsed acute myelogenous leukemia. Leuk Lymphoma. 1993 Mar; 9(4-5):343-50. PMID: 8394169.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    255. Plunkett W, Gandhi V. Cellular pharmacodynamics of anticancer drugs. Semin Oncol. 1993 Feb; 20(1):50-63. PMID: 8475410.
      Citations: 9     Fields:    Translation:Humans
    256. Gandhi V, Estey E, Keating MJ, Plunkett W. Biochemical modulation of arabinosylcytosine for therapy of leukemias. Leuk Lymphoma. 1993; 10 Suppl:109-14. PMID: 8481660.
      Citations: 13     Fields:    Translation:Humans
    257. Gandhi V, Estey E, Keating MJ, Plunkett W. Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy. J Clin Oncol. 1993 Jan; 11(1):116-24. PMID: 8418222.
      Citations: 56     Fields:    Translation:Humans
    258. Gandhi V. Fludarabine for treatment of adult acute myelogenous leukemia. Leuk Lymphoma. 1993; 11 Suppl 2:7-13. PMID: 8124234.
      Citations:    Fields:    Translation:Humans
    259. Ing TS, Yu AW, Agrawal B, Ansari AU, Leehey DJ, Gandhi VC, Nawab ZM. Increasing plasma phosphorus values by enriching with phosphorus the "acid concentrate" of a bicarbonate-buffered dialysate delivery system. Int J Artif Organs. 1992 Dec; 15(12):701-3. PMID: 1493944.
      Citations:    Fields:    Translation:Humans
    260. Gandhi VC, Jones DJ. Protein kinase C modulates the release of [3H]5-hydroxytryptamine in the spinal cord of the rat: the role of L-type voltage-dependent calcium channels. Neuropharmacology. 1992 Nov; 31(11):1101-9. PMID: 1282220.
      Citations: 2     Fields:    Translation:AnimalsCells
    261. Dalal S, Gandhi VC, Yu AW, Bhate DV, Said RA, Rahman MA, Ing TS. Penile calcification in maintenance hemodialysis patients. Urology. 1992 Nov; 40(5):422-4. PMID: 1441038.
      Citations: 3     Fields:    Translation:Humans
    262. Ing TS, Yu AW, Thompson KD, Ansari AU, McShane AP, Gandhi VC, Filkins JP. Peritoneal dialysis using conventional, lactate--containing solution sterilized by ultrafiltration. Int J Artif Organs. 1992 Nov; 15(11):658-60. PMID: 1490757.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    263. Yu AW, Zhou XJ, Zhou FQ, Nawab ZM, Gandhi VC, Ing TS, Vaziri ND. Neutrophilic intracellular acidosis induced by conventional, lactate-containing peritoneal dialysis solutions. Int J Artif Organs. 1992 Nov; 15(11):661-5. PMID: 1490758.
      Citations: 1     Fields:    Translation:HumansCells
    264. Yu AW, Soundararajan R, Nawab ZM, Gandhi VC, Rahman MA, Popli S, Ing TS. Raising plasma phosphorus levels by phosphorus-enriched, bicarbonate-containing dialysate in hemodialysis patients. Artif Organs. 1992 Aug; 16(4):414-6. PMID: 10078284.
      Citations:    Fields:    Translation:Humans
    265. Gandhi V, Kemena A, Keating MJ, Plunkett W. Fludarabine infusion potentiates arabinosylcytosine metabolism in lymphocytes of patients with chronic lymphocytic leukemia. Cancer Res. 1992 Feb 15; 52(4):897-903. PMID: 1737352.
      Citations: 18     Fields:    Translation:HumansCells
    266. Gandhi V, Plunkett W. Cell cycle-specific metabolism of arabinosyl nucleosides in K562 human leukemia cells. Cancer Chemother Pharmacol. 1992; 31(1):11-7. PMID: 1458554.
      Citations: 4     Fields:    Translation:HumansCells
    267. Kemena A, Gandhi V, Shewach DS, Keating M, Plunkett W. Inhibition of fludarabine metabolism by arabinosylcytosine during therapy. Cancer Chemother Pharmacol. 1992; 31(3):193-9. PMID: 1464155.
      Citations: 5     Fields:    Translation:HumansCells
    268. Stauderman KA, Gandhi VC, Jones DJ. Fluoxetine-induced inhibition of synaptosomal [3H]5-HT release: possible Ca(2+)-channel inhibition. Life Sci. 1992; 50(26):2125-38. PMID: 1608295.
      Citations: 5     Fields:    Translation:AnimalsCells
    269. Gandhi VK, Dalal SB, Sharma JR, Vani SN. Cardiomyopathy in children in Ahmedabad. Indian J Pediatr. 1991 Sep-Oct; 58(5):665-70. PMID: 1813411.
      Citations:    Fields:    Translation:Humans
    270. Yu AW, Manahan FJ, Filkins JP, Mohammed MS, Soundararajan R, McShane AP, Gandhi VC, Ing TS. Peritoneal dialysis using bicarbonate-containing solution sterilized by ultrafiltration. Int J Artif Organs. 1991 Aug; 14(8):463-5. PMID: 1937936.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    271. Gandhi VC, Jones DJ. G-protein modulation of [3H]serotonin release through the L-type calcium channel. Ann N Y Acad Sci. 1991; 635:455-8. PMID: 1720604.
      Citations:    Fields:    Translation:Cells
    272. Gandhi V, Huang P, Xu YZ, Heinemann V, Plunkett W. Metabolism and action of 2',2'-difluorodeoxycytidine: self-potentiation of cytotoxicity. Adv Exp Med Biol. 1991; 309A:125-30. PMID: 1789190.
      Citations: 5     Fields:    Translation:HumansCells
    273. Gandhi VC, Jones DJ. Modulation of [3H]serotonin release by dihydropyridines in spinal cord synaptosomes. Eur J Pharmacol. 1990 Oct 09; 187(2):271-80. PMID: 1703081.
      Citations: 1     Fields:    Translation:AnimalsCells
    274. Plunkett W, Huang P, Gandhi V. Metabolism and action of fludarabine phosphate. Semin Oncol. 1990 Oct; 17(5 Suppl 8):3-17. PMID: 1699280.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    275. Gandhi V, Plunkett W. Modulatory activity of 2',2'-difluorodeoxycytidine on the phosphorylation and cytotoxicity of arabinosyl nucleosides. Cancer Res. 1990 Jun 15; 50(12):3675-80. PMID: 2340517.
      Citations: 26     Fields:    Translation:HumansCells
    276. Ajam M, Ramanujam LS, Gandhi VC, Leehey DJ, Ing TS, Schnell TG, Daugirdas JT. Colon-cancer screening in dialysis patients. Artif Organs. 1990 Apr; 14(2):95-7. PMID: 2350261.
      Citations: 4     Fields:    Translation:Humans
    277. Gandhi V, Nowak B, Keating MJ, Plunkett W. Modulation of arabinosylcytosine metabolism by arabinosyl-2-fluoroadenine in lymphocytes from patients with chronic lymphocytic leukemia: implications for combination therapy. Blood. 1989 Nov 01; 74(6):2070-5. PMID: 2478221.
      Citations: 11     Fields:    Translation:HumansCells
    278. Gandhi V, Plunkett W. Interaction of arabinosyl nucleotides in K562 human leukemia cells. Biochem Pharmacol. 1989 Oct 15; 38(20):3551-8. PMID: 2479383.
      Citations: 3     Fields:    Translation:HumansCells
    279. Leehey DJ, Daugirdas JT, Popli S, Gandhi VC, Pifarré R, Ing TS. Predicting need for surgical drainage of pericardial effusion in patients with end-stage renal disease. Int J Artif Organs. 1989 Oct; 12(10):618-25. PMID: 2680996.
      Citations: 2     Fields:    Translation:Humans
    280. Manahan FJ, Ramanujam L, Ajam M, Ing TS, Gandhi VC, Daugirdas JT. Post to predialysis plasma urea nitrogen ratio, ultrafiltration and weight to estimate K.t/V. Use in auditing the amount of dialysis being administered. ASAIO Trans. 1989 Jul-Sep; 35(3):511-2. PMID: 2597521.
      Citations: 1     Fields:    Translation:Humans
    281. Gandhi VC, Ross DH. In vivo morphine decreases [3H]nimodipine receptor binding in rat brain regions. Neurochem Res. 1988 Dec; 13(12):1175-81. PMID: 2853309.
      Citations:    Fields:    Translation:Animals
    282. Gandhi VC, Jones DJ. Identification and characterization of [3H]nitrendipine binding sites in rat spinal cord. J Pharmacol Exp Ther. 1988 Nov; 247(2):473-80. PMID: 2460614.
      Citations: 1     Fields:    Translation:Animals
    283. Gandhi VC, Ross DH. The effect of kappa agonist U50-488H on [3H]nimodipine receptor binding in rat brain regions. Eur J Pharmacol. 1988 May 20; 150(1-2):51-7. PMID: 2841143.
      Citations: 3     Fields:    Translation:Animals
    284. Gandhi V, Plunkett W. Modulation of arabinosylnucleoside metabolism by arabinosylnucleotides in human leukemia cells. Cancer Res. 1988 Jan 15; 48(2):329-34. PMID: 3335008.
      Citations: 28     Fields:    Translation:HumansCells
    285. Gandhi VC, Ross DH. A novel kappa agonist inhibits [3H]nimodipine binding to a Ca++ channel receptor protein in rat brain. Biochem Biophys Res Commun. 1987 Dec 31; 149(3):1042-8. PMID: 2447885.
      Citations:    Fields:    Translation:AnimalsCells
    286. Danhauser L, Plunkett W, Liliemark J, Gandhi V, Iacoboni S, Keating M. Comparison between the plasma and intracellular pharmacology of 1-beta-D-arabinofuranosylcytosine and 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-monophosphate in patients with relapsed leukemia. Leukemia. 1987 Sep; 1(9):638-43. PMID: 3478543.
      Citations: 14     Fields:    Translation:HumansCells
    287. Gandhi VC, Ross DH. Alpha-adrenergic receptor regulation of Ca2+/Mg2+-ATPase in brain synaptic membranes. Neurochem Res. 1987 Sep; 12(9):801-7. PMID: 2890113.
      Citations: 3     Fields:    Translation:AnimalsCells
    288. Daugirdas JT, Potempa LD, Dinh N, Gandhi VC, Ivanovich PT, Ing TS. Plate, coil, and hollow-fiber cuprammonium cellulose dialyzers: discrepancy between incidence of anaphylactic reactions and degree of complement activation. Artif Organs. 1987 Apr; 11(2):140-3. PMID: 3593043.
      Citations:    Fields:    Translation:Humans
    289. Gandhi V, Danhauser L, Plunkett W. Separation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate and 9-beta-D-arabinofuranosyl-2-fluoroadenine 5'-triphosphate in human leukemia cells by high-performance liquid chromatography. J Chromatogr. 1987 Jan 23; 413:293-9. PMID: 3558682.
      Citations: 5     Fields:    Translation:HumansCells
    290. Gandhi VC, Ross DH. Alterations in alpha-adrenergic and muscarinic cholinergic receptor binding in rat brain following nonionizing radiation. Radiat Res. 1987 Jan; 109(1):90-9. PMID: 3027740.
      Citations:    Fields:    Translation:Animals
    291. Daugirdas JT, Leehey DJ, Popli S, Hoffman W, Zayas I, Gandhi VC, Ing TS. Induction of peritoneal fluid eosinophilia and/or monocytosis by intraperitoneal air injection. Am J Nephrol. 1987; 7(2):116-20. PMID: 3605232.
      Citations: 6     Fields:    Translation:HumansCells
    292. Gandhi VC, Ross DH. Effects of alcohol on alpha-adrenergic receptor regulation of calcium ATPase in liver plasma membranes. Alcohol. 1987 Jan-Feb; 4(1):25-30. PMID: 3030358.
      Citations: 2     Fields:    Translation:AnimalsCells
    293. Daugirdas JT, Gandhi VC, McShane AP, Leehey DJ, Chan AY, Jablokow VR, Ing TS. Peritoneal sclerosis in continuous ambulatory peritoneal dialysis patients dialyzed exclusively with lactate-buffered dialysate. Int J Artif Organs. 1986 Nov; 9(6):413-6. PMID: 3818115.
      Citations:    Fields:    Translation:Humans
    294. Daugirdas JT, Leehey DJ, Popli S, McCray GM, Gandhi VC, Pifarré R, Ing TS. Subxiphoid pericardiostomy for hemodialysis-associated pericardial effusion. Arch Intern Med. 1986 Jun; 146(6):1113-5. PMID: 3718097.
      Citations: 2     Fields:    Translation:Humans
    295. Daugirdas JT, Leehey DJ, Popli S, Gandhi VC, Zayas I, Hoffman W, Ing TS. Induction of peritoneal-fluid eosinophilia by intraperitoneal air in patients on continuous ambulatory peritoneal dialysis. N Engl J Med. 1985 Dec 05; 313(23):1481. PMID: 4058558.
      Citations:    Fields:    Translation:HumansCells
    296. Gandhi VC, Leehey DJ, Stanley MM, Nemchausky BA, Daugirdas JT, Greenlee HB, Jablokow VR, Ing TS. Peritoneo-venous shunting in patients with cirrhotic ascites and end-stage renal failure. Am J Kidney Dis. 1985 Sep; 6(3):185-7. PMID: 4036962.
      Citations:    Fields:    Translation:Humans
    297. Ing TS, Daugirdas JT, Nawab ZM, Gandhi VC, Leehey DJ, Popli S. Preparation of a bicarbonate-buffered, plasma-resembling parenteral solution. Int J Artif Organs. 1985 Jul; 8(4):231-2. PMID: 4055099.
      Citations:    Fields:    Translation:Humans
    298. Ing TS, Daugirdas JT, Gandhi VC, Popli S. Bicarbonate-buffered peritoneal dialysis. Int J Artif Organs. 1985 May; 8(3):121-4. PMID: 4030129.
      Citations:    Fields:    Translation:Humans
    299. Gandhi VC, Jones MA, Keenan RW. Residual complement activity after incubation with myelin isolated from both the central and peripheral nervous tissues. Mol Immunol. 1985 Apr; 22(4):495-8. PMID: 4033668.
      Citations:    Fields:    Translation:AnimalsCells
    300. Chandran PK, Humayun HM, Daugirdas JT, Nawab ZM, Gandhi VC, Ing TS. Blood eosinophilia in patients undergoing maintenance peritoneal dialysis. Arch Intern Med. 1985 Jan; 145(1):114-6. PMID: 3970622.
      Citations: 4     Fields:    Translation:Humans
    301. Popli S, Daugirdas JT, Ing TS, Geis WP, Leehey DJ, Gandhi VC. Pyocystis in a renal transplant recipient with a defunctionalized bladder. Am J Nephrol. 1985; 5(6):431-2. PMID: 3909818.
      Citations: 1     Fields:    Translation:Humans
    302. Purandare VV, Ing TS, Daugirdas JT, Gandhi VC, Chejfec G. Acquired cystic disease in kidneys of patients with chronic renal failure. Artif Organs. 1984 Nov; 8(4):501. PMID: 6508606.
      Citations:    Fields:    Translation:Humans
    303. Gutman RA, Blumenkrantz MJ, Chan YK, Barbour GL, Gandhi VC, Shen FH, Tucker T, Murawski BJ, Coburn JW, Curtis FK. Controlled comparison of hemodialysis and peritoneal dialysis: Veterans Administration multicenter study. Kidney Int. 1984 Oct; 26(4):459-70. PMID: 6396439.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    304. Humayun HM, Daugirdas JT, Ing TS, Leehey DJ, Gandhi VC, Popli S. Chylous ascites in a patient treated with intermittent peritoneal dialysis. Artif Organs. 1984 Aug; 8(3):358-60. PMID: 6477204.
      Citations: 1     Fields:    Translation:Humans
    305. Ing TS, Gandhi VC, Daugirdas JT, Reid RW, Hunt J, Popli S. Peritoneal dialysis using bicarbonate-buffered dialysate. Int J Artif Organs. 1984 May; 7(3):166. PMID: 6735508.
      Citations:    Fields:    Translation:Humans
    306. Ing TS, Purandare VV, Daugirdas JT, Hano JE, Battersby DG, Gandhi VC. Slow continuous hemodialysis. Int J Artif Organs. 1984 Jan; 7(1):53. PMID: 6698633.
      Citations:    Fields:    Translation:Animals
    307. Ing TS, Daugirdas JT, Gandhi VC. Peritoneal sclerosis in peritoneal dialysis patients. Am J Nephrol. 1984; 4(3):173-6. PMID: 6742010.
      Citations: 6     Fields:    Translation:Humans
    308. Ing TS, Daugirdas JT, Gandhi VC, Leehey DJ. Sclerosing peritonitis after peritoneal dialysis. Lancet. 1983 Nov 05; 2(8358):1080. PMID: 6138621.
      Citations:    Fields:    Translation:Humans
    309. Ing TS, Daugirdas JT, Popli S, Gandhi VC. First-use syndrome with cuprammonium cellulose dialyzers. Int J Artif Organs. 1983 Sep; 6(5):235-9. PMID: 6642720.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    310. Ing TS, Humayun HM, Daugirdas JT, Reid RW, Hano JE, Gandhi VC, Popli S. Preparation of bicarbonate-containing dialysate for peritoneal dialysis. Int J Artif Organs. 1983 Jul; 6(4):217-8. PMID: 6313530.
      Citations:    Fields:    
    311. Gandhi VC, Ing TS, Daugirdas JT, Hagen C, Blumenkrantz MJ, Jablokow VR. Failure of peritoneal dialysis due to peritoneal sclerosis. Int J Artif Organs. 1983 Mar; 6(2):97. PMID: 6840899.
      Citations: 2     Fields:    Translation:Humans
    312. Wu MJ, Osanloo EO, Molnar ZV, Daugirdas JT, Gandhi VC, Ing TS. Poststreptococcal crescentic glomerulonephritis in a patient with preexisting membranous glomerulonephropathy. Nephron. 1983; 35(1):62-5. PMID: 6888627.
      Citations: 1     Fields:    Translation:Humans
    313. Sharp ZD, Gandhi VV, Procunier JD. X chromosome nucleolus organizer mutants which alter major type I repeat multiplicity in Drosophila melanogaster. Mol Gen Genet. 1983; 190(3):438-43. PMID: 6308398.
      Citations: 6     Fields:    Translation:AnimalsCells
    314. Popli S, Stroka G, Ing TS, Daugirdas JT, Norusis MJ, Hano JE, Gandhi VC. Transdermal clonidine for hypertensive patients. Clin Ther. 1983; 5(6):624-8. PMID: 6627288.
      Citations: 6     Fields:    Translation:Humans
    315. Ing TS, Gandhi VC, Daugirdas JT, Hunt J, Reid RW, Merkel FK, Gibson S. Peritoneal dialysis using bicarbonate-containing dialysate produced by an on-line method. Artif Organs. 1982 Nov; 6(4):457-8. PMID: 7165560.
      Citations:    Fields:    Translation:Humans
    316. Giacchino JL, Geis WP, Wittenstein BH, Gandhi VC. Recent trends in vascular access. Am Surg. 1982 Oct; 48(10):501-4. PMID: 7137712.
      Citations:    Fields:    Translation:Humans
    317. Popli S, Ing TS, Daugirdas JT, Kheirbek AO, Viol GW, Vilbar RM, Gandhi VC. Severe reactions to Cuprophan capillary dialyzers. Artif Organs. 1982 Aug; 6(3):312-5. PMID: 7181733.
      Citations: 1     Fields:    Translation:Humans
    318. Al-Kudsi RR, Daugirdas JT, Ing TS, Kheirbek AO, Popli S, Hano JE, Gandhi VC. Extreme hyperglycemia in dialysis patients. Clin Nephrol. 1982 May; 17(5):228-31. PMID: 7047032.
      Citations: 14     Fields:    Translation:Humans
    319. Ing TS, Gandhi VC, Daugirdas JT, Hunt J, Quon MJ, Ropli S. Peritoneal dialysis using bicarbonate-containing dialysate produced by automated dialysate delivery machine. Artif Organs. 1982 Feb; 6(1):67-9. PMID: 7073526.
      Citations:    Fields:    Translation:Humans
    320. Gandhi VV, Sharp ZD, Procunier JD. Analysis of Y chromosome nucleolar organizer mutants in Drosophila melanogaster. Biochem Biophys Res Commun. 1982 Jan 29; 104(2):778-84. PMID: 6803790.
      Citations: 4     Fields:    Translation:AnimalsCells
    321. Wu MJ, Ing TS, Soung LS, Daugirdas JT, Hano JE, Gandhi VC. Amantadine hydrochloride pharmacokinetics in patients with impaired renal function. Clin Nephrol. 1982 Jan; 17(1):19-23. PMID: 7035042.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    322. Ing TS, Quon MJ, Daugirdas JT, Liu P, Gandhi VC, Reid RR. "One-line" preparation of bicarbonate-containing dialysate for use in peritoneal dialysis. Int J Artif Organs. 1981 Nov; 4(6):308. PMID: 7333690.
      Citations: 1     Fields:    
    323. Humayun HM, Ing TS, Daugirdas JT, Gandhi VC, Popli S, Robinson JA, Hano JE, Zayas I. Peritoneal fluid eosinophilia in patients undergoing maintenance peritoneal dialysis. Arch Intern Med. 1981 Aug; 141(9):1172-3. PMID: 7259377.
      Citations: 4     Fields:    Translation:HumansCells
    324. Giacchino JL, Geis WP, Wittenstein BH, Bansal VK, Gandhi VC, Vertuno LL. Surgery, nutritional support, and survival in patients with end-stage renal disease. Arch Surg. 1981 May; 116(5):634-40. PMID: 6786259.
      Citations:    Fields:    Translation:Humans
    325. Ing TS, Quon MJ, Daugirdas JT, Gandhi VC, Epstein MB. Preparation of bicarbonate-containing peritoneal dialysate using an automated dialysate delivery system. Int J Artif Organs. 1981 May; 4(3):148-9. PMID: 7275345.
      Citations:    Fields:    Translation:Humans
    326. Ing TS, Daugirdas JT, Popli S, Kheirbek AO, Humayun HM, Gandhi VC, Chapa SM. Treatment of refractory hemodialysis ascites with maintenance peritoneal dialysis. Clin Nephrol. 1981 Apr; 15(4):198-202. PMID: 7237867.
      Citations: 1     Fields:    Translation:Humans
    327. Daugirdas JT, Ing TS, Humayn HH, Weber DS, Chen WT, Gandhi VC, Reid RR, Hano JE. Two-hour, high-surface-area hemodialysis: a feasibility study. Int J Artif Organs. 1981 Jan; 4(1):13-6. PMID: 6783553.
      Citations:    Fields:    Translation:HumansCells
    328. Spencer H, Kramer L, Gatza C, Norris C, Wiatrowski E, Gandhi VC. Fluoride metabolism in patients with chronic renal failure. Arch Intern Med. 1980 Oct; 140(10):1331-5. PMID: 7425768.
      Citations: 1     Fields:    Translation:Humans
    329. Ing TS, Daugirdas JT, Popli S, Kheirbek AO, Gandhi VC. Treatment of refractory hemodialysis ascites with maintenance peritoneal dialysis. Int J Artif Organs. 1980 Sep; 3(5):311. PMID: 7461865.
      Citations:    Fields:    Translation:Humans
    330. Gandhi VC, Humayun HM, Ing TS, Daugirdas JT, Jablokow VR, Iwatsuki S, Geis WP, Hano JE. Sclerotic thickening of the peritoneal membrane in maintenance peritoneal dialysis patients. Arch Intern Med. 1980 Sep; 140(9):1201-3. PMID: 7406618.
      Citations: 48     Fields:    Translation:Humans
    331. Chen WT, Ing TS, Daugirdas JT, Humayun HM, Brescia DJ, Gandhi VC, Hano JE, Kheirbek AO. Hydrostatic ultrafiltration during hemodialysis using decreasing sodium dialysate. Artif Organs. 1980 Aug; 4(3):187-91. PMID: 7417032.
      Citations:    Fields:    Translation:HumansCells
    332. Soung LS, Ing TS, Daugirdas JT, Wu MJ, Gandhi VC, Ivanovich PT, Hano JE, Viol GW. Amantadine hydrochloride pharmacokinetics in hemodialysis patients. Ann Intern Med. 1980 Jul; 93(1):46-9. PMID: 7396313.
      Citations: 8     Fields:    Translation:Humans
    333. Blumenkrantz MJ, Kopple JD, Gutman RA, Chan YK, Barbour GL, Roberts C, Shen FH, Gandhi VC, Tucker CT, Curtis FK, Coburn JW. Methods for assessing nutritional status of patients with renal failure. Am J Clin Nutr. 1980 Jul; 33(7):1567-85. PMID: 7395778.
      Citations: 29     Fields:    Translation:Humans
    334. Daugirdas JT, Ing TS, Gandhi VC, Hano JE, Chen WT, Yuan L. Kinetics of peritoneal fluid absorption in patients with chronic renal failure. J Lab Clin Med. 1980 Mar; 95(3):351-61. PMID: 7354240.
      Citations: 4     Fields:    Translation:HumansCells
    335. Chen WT, Ing TS, Daugirdas JT, Brescia DJ, Humayun H, Gandhi VC, Hano JE, Quon MJ. A method of deliverying dialysate of constantly decreasing osmolality during dialysis. Artif Organs. 1979 Nov; 3(4):377-9. PMID: 533432.
      Citations:    Fields:    
    336. Vilbar RM, Daugirdas JT, Ing TS, Gandhi VC, Popli S, Chen WT. Treatment of dialysis elbow by simple aspiration. J Dial. 1979; 3(4):327-30. PMID: 263954.
      Citations:    Fields:    Translation:Humans
    337. Humayun H, Daugirdas JT, Gandhi VC, Geis WP, Giacchino J, Ing TS. Intra-abdominal abscesses in a patient treated with maintenance peritoneal dialysis. J Dial. 1979; 3(4):331-5. PMID: 263955.
      Citations:    Fields:    Translation:Humans
    338. Gandhi VC, Kamadana MR, Ing TS, Daugirdas JT, Viol GW, Robinson JA, Geis WP, Hano JE. Aseptic peritonitis in patients on maintenance peritoneal dialysis. Nephron. 1979; 24(5):257-9. PMID: 503270.
      Citations:    Fields:    Translation:Humans
    339. Kheirbek AO, Ing TS, Viol GW, Vilbar RM, Bansal VK, Gandhi VC, Geis WP, Hano JE. Treatment of metabolic alkalosis with hemofiltration in patients with renal insufficiency. Nephron. 1979; 24(2):91-2. PMID: 492418.
      Citations:    Fields:    Translation:Humans
    340. Osanloo EO, Berlin BS, Popli S, Ing TS, Cummings JE, Gandhi VC, Geis WP, Hano JE. Antibody responses to influenza vaccination in patients with chronic renal failure. Kidney Int. 1978 Dec; 14(6):614-8. PMID: 748672.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
    341. Vilbar RM, Ing TS, Shin KD, Gandhi VC, Viol GW, Chen WT, Geis WP, Hano JE. Treatment of metabolic alkalosis with peritoneal dialysis in a patient with renal failure. Artif Organs. 1978 Nov; 2(4):421-2. PMID: 743016.
      Citations:    Fields:    Translation:Humans
    342. Pillay VK, Gandhi VC, Mahurkar SD, Dunea G. Modification of mild proteinuria by postural and other mechanisms affecting haemodynamics. S Afr Med J. 1976 Sep 25; 50(41):1598-600. PMID: 982214.
      Citations:    Fields:    Translation:Humans
    343. Pillay VK, Wang F, Gandhi VC, Lee HJ, Dunea G. Uraemia from benign hypertension. S Afr Med J. 1974 May 11; 48(22):953-6. PMID: 4275958.
      Citations:    Fields:    Translation:Humans
    344. Datta SK, Gandhi VC, Lee HJ, Pillay VK, Dunea G. Granuloma in systemic lupus erythematosus. S Afr Med J. 1972 Oct 14; 46(41):1514-6. PMID: 4645026.
      Citations: 2     Fields:    Translation:Humans
    345. Pillay VK, Gandhi VC, Sharma BK, Smith EC, Dunea G. Effect of hydration and furosemide given intravenously on proteinuria. Arch Intern Med. 1972 Jul; 130(1):90-2. PMID: 5035985.
      Citations: 3     Fields:    Translation:Humans
    346. Sharma BK, Rodriguez H, Gandhi VC, Smith EC, Pillay VK, Dunea G. Trial of oral neomycin during peritoneal dialysis. Am J Med Sci. 1971 Sep; 262(3):175-8. PMID: 4946828.
      Citations:    Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    347. Bendamustine in B-cell malignancies. Clinical Cancer Research. 15:7456-7461.
    348. Clofarabine in paediatric patients with acute lymphoblastic leukaemia. Drugs and Therapy Perspectives. 22:3-5.
    349. 2',2'-difluorodeoxycytidine metabolism and mechanism of action in human leukemia cells. Nucleosides and Nucleotides. 8:775-785.
    350. Pharmacological and protein profiling suggests venetoclax (ABT-199) as optimal partner with ibrutinib in chronic lymphocytic leukemia. Clinical Cancer Research. 21:3705-3715.
    351. Gemcitabine. Nucleosides and Nucleotides. 16:1261-1270.
    352. Erratum. European Journal of Medicinal Chemistry. 124:1004-1005.
    353. Carfilzomib triggers cell death in chronic lymphocytic leukemia by inducing proapoptotic and endoplasmic reticulum stress responses. Clinical Cancer Research. 22:4712-4726.
    354. Targeting executioner procaspase-3 with the procaspase-activating compound B-PAC-1 induces apoptosis in multiple myeloma cells. Experimental Hematology. 43:951-962.e3.
    355. Combination of Pim kinase inhibitors and Bcl-2 antagonists in chronic lymphocytic leukemia cells. Leukemia and Lymphoma. 57:436-444.
    356. Pim kinases in aml. 177-199.
    357. Histological and Histochemical Studies on the Cotyledons of Some Legumes II. Reserve metabolites during seed development. Cytologia. 52:847-858.
    358. BIOMASS ENERGY PRODUCTION FROM FOREST TREES BY TISSUE CULTURE. 69-99.
    359. Does ATP promote or protect cells from apoptosis?. Cancer Biology and Therapy. 5:712.
    360. Pharmacokinetic and pharmacodynamic evaluation of ibrutinib for the treatment of chronic lymphocytic leukemia. Expert Opinion on Drug Metabolism and Toxicology. 1-12.
    361. Preclinical combination of TP-0903, an AXL inhibitor and B-PAC-1, a procaspase-activating compound with ibrutinib in chronic lymphocytic leukemia. Leukemia and Lymphoma.
    362. Idelalisib. Clinical Cancer Research. 21:1537-1542.
    363. 8-chloroadenosine sensitivity in renal cell carcinoma is associated with AMPK activation and mTOR pathway inhibition. PLoS One. 10.
    364. Forodesine. Haematologica Meeting Reports. 3:70.
    365. Nelarabine in the treatment of pediatric and adult patients with T-cell acute lymphoblastic leukemia and lymphoma. Expert Review of Hematology. 10:1-8.
    366. Cellular pharmacodynamics as a guide to leukemia therapy. Cancer Bulletin. 46:8-14.
    367. Molecular evidence of Zn chelation of the procaspase activating compound B-PAC-1 in B cell lymphoma. Oncotarget. 7:3461-3476.
    368. Erratum. Future Oncology. 11:1584.
    369. Mass propagation and genetic improvement of forest trees for biomass production by tissue culture. Biomass. 2:5-15.
    370. Clofarabine. Pediatric Drugs. 7:265-266.
    371. Idelalisib for the treatment of B-cell malignancies. Expert Opinion on Orphan Drugs. 3:109-123.
    372. Prevention and treatment of cancer. Anticancer Research. 36:4971-4975.
    373. Reactivation of smac-mediated apoptosis in chronic lymphocytic leukemia cells. Oncotarget. 7:39458-39472.
    374. ACS Symposium Series. 639:265-278.
    375. Elevated cyclin A associated kinase activity promotes sensitivity of metastatic human cancer cells to DNA antimetabolite drug. International Journal of Oncology. 47:782-790.
    376. Forodesine - Preclinical studies. Haematologica Reports. 2:35-37.
    377. Synthesis and cytotoxic activity of novel A-ring cleaved ursolic acid derivatives in human non-small cell lung cancer cells. European Journal of Medicinal Chemistry. 123:317-331.
    378. Protein profiling identifies mTOR pathway modulation and cytostatic effects of Pim kinase inhibitor, AZD1208, in acute myeloid leukemia. Leukemia and Lymphoma. 1-11.
    379. Decrease in total protein level of bruton's tyrosine kinase during ibrutinib therapy in chronic lymphocytic leukemia lymphocytes. Leukemia. 30:1803-1804.
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