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SAMIR HANASH

TitleProfessor
InstitutionMD Anderson
DepartmentClinical Cancer Prevention
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Fahrmann JF, Vykoukal J, Fleury A, Tripathi S, Dennison JB, Murage E, Wang P, Yu CY, Capello M, Creighton CJ, Do KA, Long JP, Irajizad E, Peterson C, Katayama H, Disis ML, Arun B, Hanash S. Association between plasma diacetylspermine and tumor spermine synthase with outcome in triple negative breast cancer. J Natl Cancer Inst. 2019 Sep 10. PMID: 31503278.
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    2. Riquelme E, Zhang Y, Zhang L, Montiel M, Zoltan M, Dong W, Quesada P, Sahin I, Chandra V, San Lucas A, Scheet P, Xu H, Hanash SM, Feng L, Burks JK, Do KA, Peterson CB, Nejman D, Tzeng CD, Kim MP, Sears CL, Ajami N, Petrosino J, Wood LD, Maitra A, Straussman R, Katz M, White JR, Jenq R, Wargo J, McAllister F. Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes. Cell. 2019 Aug 08; 178(4):795-806.e12. PMID: 31398337.
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    3. Chekouo T, Stingo FC, Class CA, Yan Y, Bohannan Z, Wei Y, Garcia-Manero G, Hanash S, Do KA. Investigating protein patterns in human leukemia cell line experiments: A Bayesian approach for extremely small sample sizes. Stat Methods Med Res. 2019 Jun 07; 962280219852721. PMID: 31172886.
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    4. Wang R, Song S, Harada K, Ghazanfari Amlashi F, Badgwell B, Pizzi MP, Xu Y, Zhao W, Dong X, Jin J, Wang Y, Scott A, Ma L, Huo L, Vicente D, Blum Murphy M, Shanbhag N, Tatlonghari G, Thomas I, Rogers J, Kobayashi M, Vykoukal J, Estrella JS, Roy-Chowdhuri S, Han G, Zhang S, Mao X, Song X, Zhang J, Gu J, Johnson RL, Calin GA, Peng G, Lee JS, Hanash SM, Futreal A, Wang Z, Wang L, Ajani JA. Multiplex profiling of peritoneal metastases from gastric adenocarcinoma identified novel targets and molecular subtypes that predict treatment response. Gut. 2019 Jun 06. PMID: 31171626.
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    5. Bocci F, Tripathi SC, Vilchez Mercedes SA, George JT, Casabar JP, Wong PK, Hanash SM, Levine H, Onuchic JN, Jolly MK. NRF2 activates a partial epithelial-mesenchymal transition and is maximally present in a hybrid epithelial/mesenchymal phenotype. Integr Biol (Camb). 2019 06 01; 11(6):251-263. PMID: 31329868.
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    6. Liu X, Yue Z, Cao Y, Taylor L, Zhang Q, Choi SW, Hanash S, Ito S, Chen JY, Wu H, Paczesny S. Graft-Versus-Host Disease-Free Antitumoral Signature After Allogeneic Donor Lymphocyte Injection Identified by Proteomics and Systems Biology. JCO Precis Oncol. 2019; 3. PMID: 31406955.
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    7. Katayama H, Tsou P, Kobayashi M, Capello M, Wang H, Esteva F, Disis ML, Hanash S. A plasma protein derived TGFß signature is a prognostic indicator in triple negative breast cancer. NPJ Precis Oncol. 2019; 3:10. PMID: 30963111.
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    8. Fahrmann JF, Bantis LE, Capello M, Scelo G, Dennison JB, Patel N, Murage E, Vykoukal J, Kundnani DL, Foretova L, Fabianova E, Holcatova I, Janout V, Feng Z, Yip-Schneider M, Zhang J, Brand R, Taguchi A, Maitra A, Brennan P, Max Schmidt C, Hanash S. A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2019 Apr 01; 111(4):372-379. PMID: 30137376.
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    9. Yao W, Rose JL, Wang W, Seth S, Jiang H, Taguchi A, Liu J, Yan L, Kapoor A, Hou P, Chen Z, Wang Q, Nezi L, Xu Z, Yao J, Hu B, Pettazzoni PF, Ho IL, Feng N, Ramamoorthy V, Jiang S, Deng P, Ma GJ, Den P, Tan Z, Zhang SX, Wang H, Wang YA, Deem AK, Fleming JB, Carugo A, Heffernan TP, Maitra A, Viale A, Ying H, Hanash S, DePinho RA, Draetta GF. Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer. Nature. 2019 Apr; 568(7752):410-414. PMID: 30918400.
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    10. Follia L, Ferrero G, Mandili G, Beccuti M, Giordano D, Spadi R, Satolli MA, Evangelista A, Katayama H, Hong W, Momin AA, Capello M, Hanash SM, Novelli F, Cordero F. Integrative Analysis of Novel Metabolic Subtypes in Pancreatic Cancer Fosters New Prognostic Biomarkers. Front Oncol. 2019; 9:115. PMID: 30873387.
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    11. Yan Y, Sun N, Wang H, Kobayashi M, Ladd JJ, Long JP, Lo KC, Patel J, Sullivan E, Albert T, Goodman GE, Do KA, Hanash SM. Whole Genome-Derived Tiled Peptide Arrays Detect Prediagnostic Autoantibody Signatures in Non-Small-Cell Lung Cancer. Cancer Res. 2019 Apr 01; 79(7):1549-1557. PMID: 30723114.
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    12. Jia D, George JT, Tripathi SC, Kundnani DL, Lu M, Hanash SM, Onuchic JN, Jolly MK, Levine H. Testing the gene expression classification of the EMT spectrum. Phys Biol. 2019 01 18; 16(2):025002. PMID: 30557866.
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    13. Capello M, Vykoukal JV, Katayama H, Bantis LE, Wang H, Kundnani DL, Aguilar-Bonavides C, Aguilar M, Tripathi SC, Dhillon DS, Momin AA, Peters H, Katz MH, Alvarez H, Bernard V, Ferri-Borgogno S, Brand R, Adler DG, Firpo MA, Mulvihill SJ, Molldrem JJ, Feng Z, Taguchi A, Maitra A, Hanash SM. Exosomes harbor B cell targets in pancreatic adenocarcinoma and exert decoy function against complement-mediated cytotoxicity. Nat Commun. 2019 01 16; 10(1):254. PMID: 30651550.
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    14. Guida F, Sun N, Bantis LE, Muller DC, Li P, Taguchi A, Dhillon D, Kundnani DL, Patel NJ, Yan Q, Byrnes G, Moons KGM, Tjønneland A, Panico S, Agnoli C, Vineis P, Palli D, Bueno-de-Mesquita B, Peeters PH, Agudo A, Huerta JM, Dorronsoro M, Barranco MR, Ardanaz E, Travis RC, Byrne KS, Boeing H, Steffen A, Kaaks R, Hüsing A, Trichopoulou A, Lagiou P, La Vecchia C, Severi G, Boutron-Ruault MC, Sandanger TM, Weiderpass E, Nøst TH, Tsilidis K, Riboli E, Grankvist K, Johansson M, Goodman GE, Feng Z, Brennan P, Johansson M, Hanash SM. Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins. JAMA Oncol. 2018 10 01; 4(10):e182078. PMID: 30003238.
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    15. Jolly MK, Somarelli JA, Sheth M, Biddle A, Tripathi SC, Armstrong AJ, Hanash SM, Bapat SA, Rangarajan A, Levine H. Hybrid epithelial/mesenchymal phenotypes promote metastasis and therapy resistance across carcinomas. Pharmacol Ther. 2019 Feb; 194:161-184. PMID: 30268772.
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    16. Jolly MK, Preca BT, Tripathi SC, Jia D, George JT, Hanash SM, Brabletz T, Stemmler MP, Maurer J, Levine H. Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer. APL Bioeng. 2018 Sep; 2(3):031908. PMID: 31069317.
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    17. Wang T, Fahrmann JF, Lee H, Li YJ, Tripathi SC, Yue C, Zhang C, Lifshitz V, Song J, Yuan Y, Somlo G, Jandial R, Ann D, Hanash S, Jove R, Yu H. JAK/STAT3-Regulated Fatty Acid ß-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance. Cell Metab. 2018 06 05; 27(6):1357. PMID: 29874570.
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    18. Hanash SM, Ostrin EJ, Fahrmann JF. Blood based biomarkers beyond genomics for lung cancer screening. Transl Lung Cancer Res. 2018 Jun; 7(3):327-335. PMID: 30050770.
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    19. Khosravi N, Caetano MS, Cumpian AM, Unver N, De la Garza Ramos C, Noble O, Daliri S, Hernandez BJ, Gutierrez BA, Evans SE, Hanash S, Alekseev AM, Yang Y, Chang SH, Nurieva R, Kadara H, Chen J, Ostrin EJ, Moghaddam SJ. IL22 Promotes Kras-Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties. Cancer Immunol Res. 2018 07; 6(7):788-797. PMID: 29764837.
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    20. Ostrin EJ, Little DR, Gerner-Mauro KN, Sumner EA, Ríos-Corzo R, Ambrosio E, Holt SE, Forcioli-Conti N, Akiyama H, Hanash SM, Kimura S, Huang SXL, Chen J. ß-Catenin maintains lung epithelial progenitors after lung specification. Development. 2018 03 09; 145(5). PMID: 29440304.
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    21. Cohen JD, Li L, Wang Y, Thoburn C, Afsari B, Danilova L, Douville C, Javed AA, Wong F, Mattox A, Hruban RH, Wolfgang CL, Goggins MG, Dal Molin M, Wang TL, Roden R, Klein AP, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Vogelstein JT, Browne JD, Schoen RE, Brand RE, Tie J, Gibbs P, Wong HL, Mansfield AS, Jen J, Hanash SM, Falconi M, Allen PJ, Zhou S, Bettegowda C, Diaz LA, Tomasetti C, Kinzler KW, Vogelstein B, Lennon AM, Papadopoulos N. Detection and localization of surgically resectable cancers with a multi-analyte blood test. Science. 2018 Feb 23; 359(6378):926-930. PMID: 29348365.
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    22. Shiels MS, Kirk GD, Drummond MB, Dhillon D, Hanash SM, Taguchi A, Engels EA. HIV Infection and Circulating Levels of Prosurfactant Protein B and Surfactant Protein D. J Infect Dis. 2018 01 17; 217(3):413-417. PMID: 29272472.
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    23. Unver N, Delgado O, Zeleke K, Cumpian A, Tang X, Caetano MS, Wang H, Katayama H, Yu H, Szabo E, Wistuba II, Moghaddam SJ, Hanash SM, Ostrin EJ. Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol. Int J Cancer. 2018 04 01; 142(7):1405-1417. PMID: 29134640.
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    24. Wang T, Fahrmann JF, Lee H, Li YJ, Tripathi SC, Yue C, Zhang C, Lifshitz V, Song J, Yuan Y, Somlo G, Jandial R, Ann D, Hanash S, Jove R, Yu H. JAK/STAT3-Regulated Fatty Acid ß-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance. Cell Metab. 2018 01 09; 27(1):136-150.e5. PMID: 29249690.
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    25. Hanash S. The Wide World of Molecular Profiling for Tumor Classification. Clin Chem. 2018 04; 64(4):743-744. PMID: 29097505.
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    26. Jia D, Jolly MK, Tripathi SC, Den Hollander P, Huang B, Lu M, Celiktas M, Ramirez-Peña E, Ben-Jacob E, Onuchic JN, Hanash SM, Mani SA, Levine H. Distinguishing mechanisms underlying EMT tristability. Cancer Converg. 2017; 1(1):2. PMID: 29623961.
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    27. Bocci F, Jolly MK, Tripathi SC, Aguilar M, Hanash SM, Levine H, Onuchic JN. Numb prevents a complete epithelial-mesenchymal transition by modulating Notch signalling. J R Soc Interface. 2017 11; 14(136). PMID: 29187638.
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    28. Vykoukal J, Sun N, Aguilar-Bonavides C, Katayama H, Tanaka I, Fahrmann JF, Capello M, Fujimoto J, Aguilar M, Wistuba II, Taguchi A, Ostrin EJ, Hanash SM. Plasma-derived extracellular vesicle proteins as a source of biomarkers for lung adenocarcinoma. Oncotarget. 2017 Nov 10; 8(56):95466-95480. PMID: 29221141.
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    29. Mbofung RM, McKenzie JA, Malu S, Zhang M, Peng W, Liu C, Kuiatse I, Tieu T, Williams L, Devi S, Ashkin E, Xu C, Huang L, Zhang M, Talukder AH, Tripathi SC, Khong H, Satani N, Muller FL, Roszik J, Heffernan T, Allison JP, Lizee G, Hanash SM, Proia D, Amaria R, Davis RE, Hwu P. HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes. Nat Commun. 2017 09 06; 8(1):451. PMID: 28878208.
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    30. Cohen JD, Javed AA, Thoburn C, Wong F, Tie J, Gibbs P, Schmidt CM, Yip-Schneider MT, Allen PJ, Schattner M, Brand RE, Singhi AD, Petersen GM, Hong SM, Kim SC, Falconi M, Doglioni C, Weiss MJ, Ahuja N, He J, Makary MA, Maitra A, Hanash SM, Dal Molin M, Wang Y, Li L, Ptak J, Dobbyn L, Schaefer J, Silliman N, Popoli M, Goggins MG, Hruban RH, Wolfgang CL, Klein AP, Tomasetti C, Papadopoulos N, Kinzler KW, Vogelstein B, Lennon AM. Combined circulating tumor DNA and protein biomarker-based liquid biopsy for the earlier detection of pancreatic cancers. Proc Natl Acad Sci U S A. 2017 09 19; 114(38):10202-10207. PMID: 28874546.
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    31. Basourakos SP, Davis JW, Chapin BF, Ward JF, Pettaway CA, Pisters LL, Navai N, Achim MF, Wang X, Chen HC, Choi S, Kuban D, Troncoso P, Hanash S, Thompson TC, Kim J. Baseline and longitudinal plasma caveolin-1 level as a biomarker in active surveillance for early-stage prostate cancer. BJU Int. 2018 01; 121(1):69-76. PMID: 28710901.
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    32. Kodama M, Kodama T, Newberg JY, Katayama H, Kobayashi M, Hanash SM, Yoshihara K, Wei Z, Tien JC, Rangel R, Hashimoto K, Mabuchi S, Sawada K, Kimura T, Copeland NG, Jenkins NA. In vivo loss-of-function screens identify KPNB1 as a new druggable oncogene in epithelial ovarian cancer. Proc Natl Acad Sci U S A. 2017 08 29; 114(35):E7301-E7310. PMID: 28811376.
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    33. Schliekelman MJ, Creighton CJ, Baird BN, Chen Y, Banerjee P, Bota-Rabassedas N, Ahn YH, Roybal JD, Chen F, Zhang Y, Mishra DK, Kim MP, Liu X, Mino B, Villalobos P, Rodriguez-Canales J, Behrens C, Wistuba II, Hanash SM, Kurie JM. Thy-1+ Cancer-associated Fibroblasts Adversely Impact Lung Cancer Prognosis. Sci Rep. 2017 07 25; 7(1):6478. PMID: 28744021.
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    34. Tripathi SC, Fahrmann JF, Celiktas M, Aguilar M, Marini KD, Jolly MK, Katayama H, Wang H, Murage EN, Dennison JB, Watkins DN, Levine H, Ostrin EJ, Taguchi A, Hanash SM. MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway. Cancer Res. 2017 08 15; 77(16):4414-4425. PMID: 28646020.
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    35. Jolly MK, Tripathi SC, Somarelli JA, Hanash SM, Levine H. Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding? Mol Oncol. 2017 07; 11(7):739-754. PMID: 28548388.
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    36. Kerros C, Tripathi SC, Zha D, Mehrens JM, Sergeeva A, Philips AV, Qiao N, Peters HL, Katayama H, Sukhumalchandra P, Ruisaard KE, Perakis AA, St John LS, Lu S, Mittendorf EA, Clise-Dwyer K, Herrmann AC, Alatrash G, Toniatti C, Hanash SM, Ma Q, Molldrem JJ. Neuropilin-1 mediates neutrophil elastase uptake and cross-presentation in breast cancer cells. J Biol Chem. 2017 06 16; 292(24):10295-10305. PMID: 28468826.
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    37. Inamoto Y, Martin PJ, Paczesny S, Tabellini L, Momin AA, Mumaw CL, Flowers MED, Lee SJ, Carpenter PA, Storer BE, Hanash S, Hansen JA. Association of Plasma CD163 Concentration with De Novo-Onset Chronic Graft-versus-Host Disease. Biol Blood Marrow Transplant. 2017 Aug; 23(8):1250-1256. PMID: 28455006.
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    38. Capello M, Bantis LE, Scelo G, Zhao Y, Li P, Dhillon DS, Patel NJ, Kundnani DL, Wang H, Abbruzzese JL, Maitra A, Tempero MA, Brand R, Firpo MA, Mulvihill SJ, Katz MH, Brennan P, Feng Z, Taguchi A, Hanash SM. Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer. J Natl Cancer Inst. 2017 04 01; 109(4). PMID: 28376157.
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    39. Peters HL, Tripathi SC, Kerros C, Katayama H, Garber HR, St John LS, Federico L, Meraz IM, Roth JA, Sepesi B, Majidi M, Ruisaard K, Clise-Dwyer K, Roszik J, Gibbons DL, Heymach JV, Swisher SG, Bernatchez C, Alatrash G, Hanash S, Molldrem JJ. Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells. Cancer Immunol Res. 2017 04; 5(4):319-329. PMID: 28254787.
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    40. Çeliktas M, Tanaka I, Tripathi SC, Fahrmann JF, Aguilar-Bonavides C, Villalobos P, Delgado O, Dhillon D, Dennison JB, Ostrin EJ, Wang H, Behrens C, Do KA, Gazdar AF, Hanash SM, Taguchi A. Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma. J Natl Cancer Inst. 2017 03 01; 109(3):1-9. PMID: 28376202.
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    41. Mustachio LM, Lu Y, Tafe LJ, Memoli V, Rodriguez-Canales J, Mino B, Villalobos PA, Wistuba I, Katayama H, Hanash SM, Roszik J, Kawakami M, Cho KJ, Hancock JF, Chinyengetere F, Hu S, Liu X, Freemantle SJ, Dmitrovsky E. Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer. Mol Cancer Res. 2017 07; 15(7):905-914. PMID: 28242811.
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    42. Sun N, Taguchi A, Hanash S. Switching Roles of TGF-ß in Cancer Development: Implications for Therapeutic Target and Biomarker Studies. J Clin Med. 2016 Nov 30; 5(12). PMID: 27916872.
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    43. Rho JH, Ladd JJ, Li CI, Potter JD, Zhang Y, Shelley D, Shibata D, Coppola D, Yamada H, Toyoda H, Tada T, Kumada T, Brenner DE, Hanash SM, Lampe PD. Protein and glycomic plasma markers for early detection of adenoma and colon cancer. Gut. 2018 03; 67(3):473-484. PMID: 27821646.
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    44. Chen Y, Guo H, Terajima M, Banerjee P, Liu X, Yu J, Momin AA, Katayama H, Hanash SM, Burns AR, Fields GB, Yamauchi M, Kurie JM. Lysyl Hydroxylase 2 Is Secreted by Tumor Cells and Can Modify Collagen in the Extracellular Space. J Biol Chem. 2016 Dec 09; 291(50):25799-25808. PMID: 27803159.
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    45. Tsou P, Katayama H, Ostrin EJ, Hanash SM. The Emerging Role of B Cells in Tumor Immunity. Cancer Res. 2016 10 01; 76(19):5597-5601. PMID: 27634765.
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    46. Zhang C, Suo J, Katayama H, Wei Y, Garcia-Manero G, Hanash S. Quantitative proteomic analysis of histone modifications in decitabine sensitive and resistant leukemia cell lines. Clin Proteomics. 2016; 13:14. PMID: 27382363.
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    47. Fu R, Wang P, Ma W, Taguchi A, Wong CH, Zhang Q, Gazdar A, Hanash SM, Zhou Q, Zhong H, Feng Z. A statistical method for detecting differentially expressed SNVs based on next-generation RNA-seq data. Biometrics. 2017 03; 73(1):42-51. PMID: 27276420.
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    48. Jolly MK, Tripathi SC, Jia D, Mooney SM, Celiktas M, Hanash SM, Mani SA, Pienta KJ, Ben-Jacob E, Levine H. Stability of the hybrid epithelial/mesenchymal phenotype. Oncotarget. 2016 May 10; 7(19):27067-84. PMID: 27008704.
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    49. Li W, Liu L, Gomez A, Zhang J, Ramadan A, Zhang Q, Choi SW, Zhang P, Greenson JK, Liu C, Jiang D, Virts E, Kelich SL, Chu HW, Flynn R, Blazar BR, Hanenberg H, Hanash S, Paczesny S. Proteomics analysis reveals a Th17-prone cell population in presymptomatic graft-versus-host disease. JCI Insight. 2016 May 05; 1(6). PMID: 27195312.
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    50. Caetano MS, Zhang H, Cumpian AM, Gong L, Unver N, Ostrin EJ, Daliri S, Chang SH, Ochoa CE, Hanash S, Behrens C, Wistuba II, Sternberg C, Kadara H, Ferreira CG, Watowich SS, Moghaddam SJ. IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer. Cancer Res. 2016 06 01; 76(11):3189-99. PMID: 27197187.
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    51. Wang OH, Azizian N, Guo M, Capello M, Deng D, Zang F, Fry J, Katz MH, Fleming JB, Lee JE, Wolff RA, Hanash S, Wang H, Maitra A. Prognostic and Functional Significance of MAP4K5 in Pancreatic Cancer. PLoS One. 2016; 11(3):e0152300. PMID: 27023625.
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    52. Tripathi SC, Peters HL, Taguchi A, Katayama H, Wang H, Momin A, Jolly MK, Celiktas M, Rodriguez-Canales J, Liu H, Behrens C, Wistuba II, Ben-Jacob E, Levine H, Molldrem JJ, Hanash SM, Ostrin EJ. Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome. Proc Natl Acad Sci U S A. 2016 Mar 15; 113(11):E1555-64. PMID: 26929325.
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    53. Redis RS, Vela LE, Lu W, Ferreira de Oliveira J, Ivan C, Rodriguez-Aguayo C, Adamoski D, Pasculli B, Taguchi A, Chen Y, Fernandez AF, Valledor L, Van Roosbroeck K, Chang S, Shah M, Kinnebrew G, Han L, Atlasi Y, Cheung LH, Huang GY, Monroig P, Ramirez MS, Catela Ivkovic T, Van L, Ling H, Gafà R, Kapitanovic S, Lanza G, Bankson JA, Huang P, Lai SY, Bast RC, Rosenblum MG, Radovich M, Ivan M, Bartholomeusz G, Liang H, Fraga MF, Widger WR, Hanash S, Berindan-Neagoe I, Lopez-Berestein G, Ambrosio ALB, Gomes Dias SM, Calin GA. Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2. Mol Cell. 2016 Feb 18; 61(4):640. PMID: 28934601.
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    54. Hanash S, Taguchi A, Wang H, Ostrin EJ. Deciphering the complexity of the cancer proteome for diagnostic applications. Expert Rev Mol Diagn. 2016; 16(4):399-405. PMID: 26694525.
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    55. Redis RS, Vela LE, Lu W, Ferreira de Oliveira J, Ivan C, Rodriguez-Aguayo C, Adamoski D, Pasculli B, Taguchi A, Chen Y, Fernandez AF, Valledor L, Van Roosbroeck K, Chang S, Shah M, Kinnebrew G, Han L, Atlasi Y, Cheung LH, Huang GY, Monroig P, Ramirez MS, Catela Ivkovic T, Van L, Ling H, Gafà R, Kapitanovic S, Lanza G, Bankson JA, Huang P, Lai SY, Bast RC, Rosenblum MG, Radovich M, Ivan M, Bartholomeusz G, Liang H, Fraga MF, Widger WR, Hanash S, Berindan-Neagoe I, Lopez-Berestein G, Ambrosio ALB, Gomes Dias SM, Calin GA. Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2. Mol Cell. 2016 Feb 18; 61(4):520-534. PMID: 26853146.
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    56. Ruhaak LR, Stroble C, Dai J, Barnett M, Taguchi A, Goodman GE, Miyamoto S, Gandara D, Feng Z, Lebrilla CB, Hanash S. Serum Glycans as Risk Markers for Non-Small Cell Lung Cancer. Cancer Prev Res (Phila). 2016 Apr; 9(4):317-23. PMID: 26813970.
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    57. Lim SO, Li CW, Xia W, Lee HH, Chang SS, Shen J, Hsu JL, Raftery D, Djukovic D, Gu H, Chang WC, Wang HL, Chen ML, Huo L, Chen CH, Wu Y, Sahin A, Hanash SM, Hortobagyi GN, Hung MC. EGFR Signaling Enhances Aerobic Glycolysis in Triple-Negative Breast Cancer Cells to Promote Tumor Growth and Immune Escape. Cancer Res. 2016 Mar 01; 76(5):1284-96. PMID: 26759242.
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    58. Pankova D, Chen Y, Terajima M, Schliekelman MJ, Baird BN, Fahrenholtz M, Sun L, Gill BJ, Vadakkan TJ, Kim MP, Ahn YH, Roybal JD, Liu X, Parra Cuentas ER, Rodriguez J, Wistuba II, Creighton CJ, Gibbons DL, Hicks JM, Dickinson ME, West JL, Grande-Allen KJ, Hanash SM, Yamauchi M, Kurie JM. Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma. Mol Cancer Res. 2016 Mar; 14(3):287-95. PMID: 26631572.
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    59. Annesley T, Diamandis E, Bachmann L, Hanash S, Hart B, Javahery R, Singh R, Smith R. A Spectrum of Views on Clinical Mass Spectrometry. Clin Chem. 2016 Jan; 62(1):30-6. PMID: 26553793.
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    60. Taguchi A, Rho JH, Yan Q, Zhang Y, Zhao Y, Xu H, Tripathi SC, Wang H, Brenner DE, Kucherlapati M, Kucherlapati R, Boutin AT, Wang YA, DePinho RA, Feng Z, Lampe PD, Hanash SM. MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas. Cancer Prev Res (Phila). 2015 Nov; 8(11):1112-9. PMID: 26342024.
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    61. Wikoff WR, Hanash S, DeFelice B, Miyamoto S, Barnett M, Zhao Y, Goodman G, Feng Z, Gandara D, Fiehn O, Taguchi A. Diacetylspermine Is a Novel Prediagnostic Serum Biomarker for Non-Small-Cell Lung Cancer and Has Additive Performance With Pro-Surfactant Protein B. J Clin Oncol. 2015 Nov 20; 33(33):3880-6. PMID: 26282655.
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    62. Akil A, Zhang Q, Mumaw CL, Raiker N, Yu J, Velez de Mendizabal N, Haneline LS, Robertson KA, Skiles J, Diaz-Ricart M, Carreras E, Renbarger J, Hanash S, Bies RR, Paczesny S. Biomarkers for Diagnosis and Prognosis of Sinusoidal Obstruction Syndrome after Hematopoietic Cell Transplantation. Biol Blood Marrow Transplant. 2015 Oct; 21(10):1739-45. PMID: 26172478.
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    64. Capello M, Lee M, Wang H, Babel I, Katz MH, Fleming JB, Maitra A, Wang H, Tian W, Taguchi A, Hanash SM. Carboxylesterase 2 as a Determinant of Response to Irinotecan and Neoadjuvant FOLFIRINOX Therapy in Pancreatic Ductal Adenocarcinoma. J Natl Cancer Inst. 2015 Aug; 107(8). PMID: 26025324.
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    65. Miyamoto S, Taylor SL, Barupal DK, Taguchi A, Wohlgemuth G, Wikoff WR, Yoneda KY, Gandara DR, Hanash SM, Kim K, Fiehn O. Systemic Metabolomic Changes in Blood Samples of Lung Cancer Patients Identified by Gas Chromatography Time-of-Flight Mass Spectrometry. Metabolites. 2015 Apr 09; 5(2):192-210. PMID: 25859693.
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    66. Mischak H, Critselis E, Hanash S, Gallagher WM, Vlahou A, Ioannidis JP. Epidemiologic design and analysis for proteomic studies: a primer on -omic technologies. Am J Epidemiol. 2015 May 01; 181(9):635-47. PMID: 25792606.
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    67. Wang H, Hanash S. Mass spectrometry based proteomics for absolute quantification of proteins from tumor cells. Methods. 2015 Jun 15; 81:34-40. PMID: 25794949.
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    68. Suo J, Medina D, Herrera S, Zheng ZY, Jin L, Chamness GC, Contreras A, Gutierrez C, Hilsenbeck S, Umar A, Foekens JA, Hanash S, Schiff R, Zhang XH, Chang EC. Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells. Cell Biosci. 2015; 5:10. PMID: 25774287.
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    69. Schliekelman MJ, Taguchi A, Zhu J, Dai X, Rodriguez J, Celiktas M, Zhang Q, Chin A, Wong CH, Wang H, McFerrin L, Selamat SA, Yang C, Kroh EM, Garg KS, Behrens C, Gazdar AF, Laird-Offringa IA, Tewari M, Wistuba II, Thiery JP, Hanash SM. Molecular portraits of epithelial, mesenchymal, and hybrid States in lung adenocarcinoma and their relevance to survival. Cancer Res. 2015 May 01; 75(9):1789-800. PMID: 25744723.
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    70. Taguchi A, Delgado O, Celiktas M, Katayama H, Wang H, Gazdar AF, Hanash SM. Proteomic signatures associated with p53 mutational status in lung adenocarcinoma. Proteomics. 2014 Dec; 14(23-24):2750-9. PMID: 25331784.
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    71. Lu M, Huang B, Hanash SM, Onuchic JN, Ben-Jacob E. Modeling putative therapeutic implications of exosome exchange between tumor and immune cells. Proc Natl Acad Sci U S A. 2014 Oct 07; 111(40):E4165-74. PMID: 25246552.
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    72. Taguchi A, Taylor AD, Rodriguez J, Celiktas M, Liu H, Ma X, Zhang Q, Wong CH, Chin A, Girard L, Behrens C, Lam WL, Lam S, Minna JD, Wistuba II, Gazdar AF, Hanash SM. A search for novel cancer/testis antigens in lung cancer identifies VCX/Y genes, expanding the repertoire of potential immunotherapeutic targets. Cancer Res. 2014 Sep 01; 74(17):4694-705. PMID: 24970476.
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    73. Mao J, Ladd J, Gad E, Rastetter L, Johnson MM, Marzbani E, Childs JS, Lu H, Dang Y, Broussard E, Stanton SE, Hanash SM, Disis ML. Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer. J Transl Med. 2014 May 10; 12:121. PMID: 24886063.
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    74. Hanash S, Schliekelman M. Proteomic profiling of the tumor microenvironment: recent insights and the search for biomarkers. Genome Med. 2014 Feb 27; 6(2):12. PMID: 24713112.
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    75. Hanash SM, Taguchi A. Mouse to human blood-based cancer biomarker discovery strategies. Cold Spring Harb Protoc. 2014 Feb 01; 2014(2):144-9. PMID: 24173314.
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    76. Peng G, Chun-Jen Lin C, Mo W, Dai H, Park YY, Kim SM, Peng Y, Mo Q, Siwko S, Hu R, Lee JS, Hennessy B, Hanash S, Mills GB, Lin SY. Genome-wide transcriptome profiling of homologous recombination DNA repair. Nat Commun. 2014; 5:3361. PMID: 24553445.
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    77. Prentice RL, Zhao S, Johnson M, Aragaki A, Hsia J, Jackson RD, Rossouw JE, Manson JE, Hanash SM. Proteomic risk markers for coronary heart disease and stroke: validation and mediation of randomized trial hormone therapy effects on these diseases. Genome Med. 2013; 5(12):112. PMID: 24373343.
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    78. Sin DD, Tammemagi CM, Lam S, Barnett MJ, Duan X, Tam A, Auman H, Feng Z, Goodman GE, Hanash S, Taguchi A. Pro-surfactant protein B as a biomarker for lung cancer prediction. J Clin Oncol. 2013 Dec 20; 31(36):4536-43. PMID: 24248694.
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    79. Zhang S, Mercado-Uribe I, Hanash S, Liu J. iTRAQ-based proteomic analysis of polyploid giant cancer cells and budding progeny cells reveals several distinct pathways for ovarian cancer development. PLoS One. 2013; 8(11):e80120. PMID: 24348907.
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    80. Tam KW, Zhang W, Soh J, Stastny V, Chen M, Sun H, Thu K, Rios JJ, Yang C, Marconett CN, Selamat SA, Laird-Offringa IA, Taguchi A, Hanash S, Shames D, Ma X, Zhang MQ, Lam WL, Gazdar A. CDKN2A/p16 inactivation mechanisms and their relationship to smoke exposure and molecular features in non-small-cell lung cancer. J Thorac Oncol. 2013 Nov; 8(11):1378-88. PMID: 24077454.
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    81. Vander Lugt MT, Braun TM, Hanash S, Ritz J, Ho VT, Antin JH, Zhang Q, Wong CH, Wang H, Chin A, Gomez A, Harris AC, Levine JE, Choi SW, Couriel D, Reddy P, Ferrara JL, Paczesny S. ST2 as a marker for risk of therapy-resistant graft-versus-host disease and death. N Engl J Med. 2013 Aug 08; 369(6):529-39. PMID: 23924003.
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    82. Ruhaak LR, Nguyen UT, Stroble C, Taylor SL, Taguchi A, Hanash SM, Lebrilla CB, Kim K, Miyamoto S. Enrichment strategies in glycomics-based lung cancer biomarker development. Proteomics Clin Appl. 2013 Oct; 7(9-10):664-76. PMID: 23640812.
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    83. Taguchi A, Hanash S, Rundle A, McKeague IW, Tang D, Darakjy S, Gaziano JM, Sesso HD, Perera F. Circulating pro-surfactant protein B as a risk biomarker for lung cancer. Cancer Epidemiol Biomarkers Prev. 2013 Oct; 22(10):1756-61. PMID: 23897585.
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    84. Hansen JA, Hanash SM, Tabellini L, Baik C, Lawler RL, Grogan BM, Storer B, Chin A, Johnson M, Wong CH, Zhang Q, Martin PJ, McDonald GB. A novel soluble form of Tim-3 associated with severe graft-versus-host disease. Biol Blood Marrow Transplant. 2013 Sep; 19(9):1323-30. PMID: 23791624.
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    86. Chao T, Ladd JJ, Qiu J, Johnson MM, Israel R, Chin A, Wang H, Prentice RL, Feng Z, Disis ML, Hanash S. Proteomic profiling of the autoimmune response to breast cancer antigens uncovers a suppressive effect of hormone therapy. Proteomics Clin Appl. 2013 Jun; 7(5-6):327-36. PMID: 23401414.
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    87. Wu SL, Taylor AD, Lu Q, Hanash SM, Im H, Snyder M, Hancock WS. Identification of potential glycan cancer markers with sialic acid attached to sialic acid and up-regulated fucosylated galactose structures in epidermal growth factor receptor secreted from A431 cell line. Mol Cell Proteomics. 2013 May; 12(5):1239-49. PMID: 23371026.
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    88. Ladd JJ, Chao T, Johnson MM, Qiu J, Chin A, Israel R, Pitteri SJ, Mao J, Wu M, Amon LM, McIntosh M, Li C, Prentice R, Disis N, Hanash S. Autoantibody signatures involving glycolysis and splicesome proteins precede a diagnosis of breast cancer among postmenopausal women. Cancer Res. 2013 Mar 01; 73(5):1502-13. PMID: 23269276.
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    89. Liu S, Im H, Bairoch A, Cristofanilli M, Chen R, Deutsch EW, Dalton S, Fenyo D, Fanayan S, Gates C, Gaudet P, Hincapie M, Hanash S, Kim H, Jeong SK, Lundberg E, Mias G, Menon R, Mu Z, Nice E, Paik YK, Uhlen M, Wells L, Wu SL, Yan F, Zhang F, Zhang Y, Snyder M, Omenn GS, Beavis RC, Hancock WS. A chromosome-centric human proteome project (C-HPP) to characterize the sets of proteins encoded in chromosome 17. J Proteome Res. 2013 Jan 04; 12(1):45-57. PMID: 23259914.
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    90. LeBeau AM, Lee M, Murphy ST, Hann BC, Warren RS, Delos Santos R, Kurhanewicz J, Hanash SM, VanBrocklin HF, Craik CS. Imaging a functional tumorigenic biomarker in the transformed epithelium. Proc Natl Acad Sci U S A. 2013 Jan 02; 110(1):93-8. PMID: 23248318.
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    91. Taguchi A, Hanash SM. Unleashing the power of proteomics to develop blood-based cancer markers. Clin Chem. 2013 Jan; 59(1):119-26. PMID: 23099557.
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    92. Hanash S. A call for a fresh new look at the plasma proteome. Proteomics Clin Appl. 2012 Oct; 6(9-10):443-6. PMID: 22930569.
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    93. Thomé CH, dos Santos GA, Ferreira GA, Scheucher PS, Izumi C, Leopoldino AM, Simão AM, Ciancaglini P, de Oliveira KT, Chin A, Hanash SM, Falcão RP, Rego EM, Greene LJ, Faça VM. Linker for activation of T-cell family member2 (LAT2) a lipid raft adaptor protein for AKT signaling, is an early mediator of alkylphospholipid anti-leukemic activity. Mol Cell Proteomics. 2012 Dec; 11(12):1898-912. PMID: 23001822.
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    94. Li CI, Mirus JE, Zhang Y, Ramirez AB, Ladd JJ, Prentice RL, McIntosh MW, Hanash SM, Lampe PD. Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study. Breast Cancer Res Treat. 2012 Sep; 135(2):611-8. PMID: 22903690.
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    95. Lu H, Ladd J, Feng Z, Wu M, Goodell V, Pitteri SJ, Li CI, Prentice R, Hanash SM, Disis ML. Evaluation of known oncoantibodies, HER2, p53, and cyclin B1, in prediagnostic breast cancer sera. Cancer Prev Res (Phila). 2012 Aug; 5(8):1036-43. PMID: 22715141.
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    96. Press JZ, Reyes M, Pitteri SJ, Pennil C, Garcia R, Goff BA, Hanash SM, Swisher EM. Microparticles from ovarian carcinomas are shed into ascites and promote cell migration. Int J Gynecol Cancer. 2012 May; 22(4):546-52. PMID: 22315094.
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    97. Paik YK, Omenn GS, Uhlen M, Hanash S, Marko-Varga G, Aebersold R, Bairoch A, Yamamoto T, Legrain P, Lee HJ, Na K, Jeong SK, He F, Binz PA, Nishimura T, Keown P, Baker MS, Yoo JS, Garin J, Archakov A, Bergeron J, Salekdeh GH, Hancock WS. Standard guidelines for the chromosome-centric human proteome project. J Proteome Res. 2012 Apr 06; 11(4):2005-13. PMID: 22443261.
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    98. Kani K, Faca VM, Hughes LD, Zhang W, Fang Q, Shahbaba B, Luethy R, Erde J, Schmidt J, Pitteri SJ, Zhang Q, Katz JE, Gross ME, Plevritis SK, McIntosh MW, Jain A, Hanash S, Agus DB, Mallick P. Quantitative proteomic profiling identifies protein correlates to EGFR kinase inhibition. Mol Cancer Ther. 2012 May; 11(5):1071-81. PMID: 22411897.
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    99. Hanash S, Schliekelman M, Zhang Q, Taguchi A. Integration of proteomics into systems biology of cancer. Wiley Interdiscip Rev Syst Biol Med. 2012 Jul-Aug; 4(4):327-37. PMID: 22407608.
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    100. Paik YK, Jeong SK, Omenn GS, Uhlen M, Hanash S, Cho SY, Lee HJ, Na K, Choi EY, Yan F, Zhang F, Zhang Y, Snyder M, Cheng Y, Chen R, Marko-Varga G, Deutsch EW, Kim H, Kwon JY, Aebersold R, Bairoch A, Taylor AD, Kim KY, Lee EY, Hochstrasser D, Legrain P, Hancock WS. The Chromosome-Centric Human Proteome Project for cataloging proteins encoded in the genome. Nat Biotechnol. 2012 Mar 07; 30(3):221-3. PMID: 22398612.
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    101. Amon LM, Pitteri SJ, Li CI, McIntosh M, Ladd JJ, Disis M, Porter P, Wong CH, Zhang Q, Lampe P, Prentice RL, Hanash SM. Concordant release of glycolysis proteins into the plasma preceding a diagnosis of ER+ breast cancer. Cancer Res. 2012 Apr 15; 72(8):1935-42. PMID: 22367215.
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    102. Ladd JJ, Busald T, Johnson MM, Zhang Q, Pitteri SJ, Wang H, Brenner DE, Lampe PD, Kucherlapati R, Feng Z, Prentice RL, Hanash SM. Increased plasma levels of the APC-interacting protein MAPRE1, LRG1, and IGFBP2 preceding a diagnosis of colorectal cancer in women. Cancer Prev Res (Phila). 2012 Apr; 5(4):655-64. PMID: 22277732.
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    103. Hanash S, Taguchi A. Application of proteomics to cancer early detection. Cancer J. 2011 Nov-Dec; 17(6):423-8. PMID: 22157286.
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    105. Hanash SM. Why have protein biomarkers not reached the clinic? Genome Med. 2011 Oct 26; 3(10):66. PMID: 22030259.
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    106. Schliekelman MJ, Gibbons DL, Faca VM, Creighton CJ, Rizvi ZH, Zhang Q, Wong CH, Wang H, Ungewiss C, Ahn YH, Shin DH, Kurie JM, Hanash SM. Targets of the tumor suppressor miR-200 in regulation of the epithelial-mesenchymal transition in cancer. Cancer Res. 2011 Dec 15; 71(24):7670-82. PMID: 21987723.
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    107. Ferrara JL, Harris AC, Greenson JK, Braun TM, Holler E, Teshima T, Levine JE, Choi SW, Huber E, Landfried K, Akashi K, Vander Lugt M, Reddy P, Chin A, Zhang Q, Hanash S, Paczesny S. Regenerating islet-derived 3-alpha is a biomarker of gastrointestinal graft-versus-host disease. Blood. 2011 Dec 15; 118(25):6702-8. PMID: 21979939.
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    108. Taguchi A, Politi K, Pitteri SJ, Lockwood WW, Faça VM, Kelly-Spratt K, Wong CH, Zhang Q, Chin A, Park KS, Goodman G, Gazdar AF, Sage J, Dinulescu DM, Kucherlapati R, Depinho RA, Kemp CJ, Varmus HE, Hanash SM. Lung cancer signatures in plasma based on proteome profiling of mouse tumor models. Cancer Cell. 2011 Sep 13; 20(3):289-99. PMID: 21907921.
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    109. Fang Q, Kani K, Faca VM, Zhang W, Zhang Q, Jain A, Hanash S, Agus DB, McIntosh MW, Mallick P. Impact of protein stability, cellular localization, and abundance on proteomic detection of tumor-derived proteins in plasma. PLoS One. 2011; 6(7):e23090. PMID: 21829587.
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    110. Pitteri SJ, Kelly-Spratt KS, Gurley KE, Kennedy J, Buson TB, Chin A, Wang H, Zhang Q, Wong CH, Chodosh LA, Nelson PS, Hanash SM, Kemp CJ. Tumor microenvironment-derived proteins dominate the plasma proteome response during breast cancer induction and progression. Cancer Res. 2011 Aug 01; 71(15):5090-100. PMID: 21653680.
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    111. Zeng Z, Hincapie M, Pitteri SJ, Hanash S, Schalkwijk J, Hogan JM, Wang H, Hancock WS. A proteomics platform combining depletion, multi-lectin affinity chromatography (M-LAC), and isoelectric focusing to study the breast cancer proteome. Anal Chem. 2011 Jun 15; 83(12):4845-54. PMID: 21513341.
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    112. Kelly-Spratt KS, Pitteri SJ, Gurley KE, Liggitt D, Chin A, Kennedy J, Wong CH, Zhang Q, Buson TB, Wang H, Hanash SM, Kemp CJ. Plasma proteome profiles associated with inflammation, angiogenesis, and cancer. PLoS One. 2011 May 12; 6(5):e19721. PMID: 21589862.
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    113. Hanash S. Harnessing the immune response for cancer detection. Cancer Epidemiol Biomarkers Prev. 2011 Apr; 20(4):569-70. PMID: 21454417.
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    114. Hanash S. Progress in mining the human proteome for disease applications. OMICS. 2011 Mar; 15(3):133-9. PMID: 21375461.
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    115. Hanash SM, Baik CS, Kallioniemi O. Emerging molecular biomarkers--blood-based strategies to detect and monitor cancer. Nat Rev Clin Oncol. 2011 Mar; 8(3):142-50. PMID: 21364687.
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    117. Wang H, Hanash S. Intact-protein analysis system for discovery of serum-based disease biomarkers. Methods Mol Biol. 2011; 728:69-85. PMID: 21468941.
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    118. Zhang Q, Faca V, Hanash S. Mining the plasma proteome for disease applications across seven logs of protein abundance. J Proteome Res. 2011 Jan 07; 10(1):46-50. PMID: 21062094.
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    119. Pitteri SJ, Hanash SM. Confounding effects of hormone replacement therapy in protein biomarker studies. Cancer Epidemiol Biomarkers Prev. 2011 Jan; 20(1):134-9. PMID: 21037107.
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    120. Pitteri SJ, Amon LM, Busald Buson T, Zhang Y, Johnson MM, Chin A, Kennedy J, Wong CH, Zhang Q, Wang H, Lampe PD, Prentice RL, McIntosh MW, Hanash SM, Li CI. Detection of elevated plasma levels of epidermal growth factor receptor before breast cancer diagnosis among hormone therapy users. Cancer Res. 2010 Nov 01; 70(21):8598-606. PMID: 20959476.
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    121. Hanash S, Taguchi A. The grand challenge to decipher the cancer proteome. Nat Rev Cancer. 2010 09; 10(9):652-60. PMID: 20733593.
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    122. Prentice RL, Paczesny S, Aragaki A, Amon LM, Chen L, Pitteri SJ, McIntosh M, Wang P, Buson Busald T, Hsia J, Jackson RD, Rossouw JE, Manson JE, Johnson K, Eaton C, Hanash SM. Novel proteins associated with risk for coronary heart disease or stroke among postmenopausal women identified by in-depth plasma proteome profiling. Genome Med. 2010 Jul 28; 2(7):48. PMID: 20667078.
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    123. Paczesny S, Braun TM, Levine JE, Hogan J, Crawford J, Coffing B, Olsen S, Choi SW, Wang H, Faca V, Pitteri S, Zhang Q, Chin A, Kitko C, Mineishi S, Yanik G, Peres E, Hanauer D, Wang Y, Reddy P, Hanash S, Ferrara JL. Elafin is a biomarker of graft-versus-host disease of the skin. Sci Transl Med. 2010 Jan 06; 2(13):13ra2. PMID: 20371463.
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    124. Pitteri S, Hanash S. A systems approach to the proteomic identification of novel cancer biomarkers. Dis Markers. 2010; 28(4):233-9. PMID: 20534908.
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    125. Pitteri SJ, Hanash SM, Aragaki A, Amon LM, Chen L, Busald Buson T, Paczesny S, Katayama H, Wang H, Johnson MM, Zhang Q, McIntosh M, Wang P, Kooperberg C, Rossouw JE, Jackson RD, Manson JE, Hsia J, Liu S, Martin L, Prentice RL. Postmenopausal estrogen and progestin effects on the serum proteome. Genome Med. 2009 Dec 24; 1(12):121. PMID: 20034393.
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    126. Wang H, Wong CH, Chin A, Kennedy J, Zhang Q, Hanash S. Quantitative serum proteomics using dual stable isotope coding and nano LC-MS/MSMS. J Proteome Res. 2009 Dec; 8(12):5412-22. PMID: 19817497.
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    127. Pitteri SJ, JeBailey L, Faça VM, Thorpe JD, Silva MA, Ireton RC, Horton MB, Wang H, Pruitt LC, Zhang Q, Cheng KH, Urban N, Hanash SM, Dinulescu DM. Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery. PLoS One. 2009 Nov 19; 4(11):e7916. PMID: 19936259.
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    128. Zeng Z, Hincapie M, Haab BB, Hanash S, Pitteri SJ, Kluck S, Hogan JM, Kennedy J, Hancock WS. The development of an integrated platform to identify breast cancer glycoproteome changes in human serum. J Chromatogr A. 2010 May 07; 1217(19):3307-15. PMID: 19782370.
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    129. Garcia J, Faca V, Jarzembowski J, Zhang Q, Park J, Hanash S. Comprehensive profiling of the cell surface proteome of Sy5Y neuroblastoma cells yields a subset of proteins associated with tumor differentiation. J Proteome Res. 2009 Aug; 8(8):3791-6. PMID: 19505085.
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    130. Jeong SK, Kwon MS, Lee EY, Lee HJ, Cho SY, Kim H, Yoo JS, Omenn GS, Aebersold R, Hanash S, Paik YK. BiomarkerDigger: a versatile disease proteome database and analysis platform for the identification of plasma cancer biomarkers. Proteomics. 2009 Jul; 9(14):3729-40. PMID: 19639590.
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    131. Taylor AD, Hancock WS, Hincapie M, Taniguchi N, Hanash SM. Towards an integrated proteomic and glycomic approach to finding cancer biomarkers. Genome Med. 2009 Jun 04; 1(6):57. PMID: 19519948.
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    132. Bell AW, Deutsch EW, Au CE, Kearney RE, Beavis R, Sechi S, Nilsson T, Bergeron JJ. A HUPO test sample study reveals common problems in mass spectrometry-based proteomics. Nat Methods. 2009 Jun; 6(6):423-30. PMID: 19448641.
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    133. Diamandis EP, Hanash S, Lopez M, Carr S, Petricoin EF. Protein quantification by mass spectrometry: is it ready for prime time? Clin Chem. 2009 Jul; 55(7):1427-30. PMID: 19443560.
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    134. Katayama H, Paczesny S, Prentice R, Aragaki A, Faca VM, Pitteri SJ, Zhang Q, Wang H, Silva M, Kennedy J, Rossouw J, Jackson R, Hsia J, Chlebowski R, Manson J, Hanash S. Application of serum proteomics to the Women's Health Initiative conjugated equine estrogens trial reveals a multitude of effects relevant to clinical findings. Genome Med. 2009 Apr 29; 1(4):47. PMID: 19402886.
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    135. Vilar E, Mukherjee B, Kuick R, Raskin L, Misek DE, Taylor JM, Giordano TJ, Hanash SM, Fearon ER, Rennert G, Gruber SB. Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. Clin Cancer Res. 2009 Apr 15; 15(8):2829-39. PMID: 19351759.
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    136. Harsha HC, Kandasamy K, Ranganathan P, Rani S, Ramabadran S, Gollapudi S, Balakrishnan L, Dwivedi SB, Telikicherla D, Selvan LD, Goel R, Mathivanan S, Marimuthu A, Kashyap M, Vizza RF, Mayer RJ, Decaprio JA, Srivastava S, Hanash SM, Hruban RH, Pandey A. A compendium of potential biomarkers of pancreatic cancer. PLoS Med. 2009 Apr 07; 6(4):e1000046. PMID: 19360088.
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    137. Qiu J, Hanash S. Autoantibody profiling for cancer detection. Clin Lab Med. 2009 Mar; 29(1):31-46. PMID: 19389549.
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    138. Hung KE, Faca V, Song K, Sarracino DA, Richard LG, Krastins B, Forrester S, Porter A, Kunin A, Mahmood U, Haab BB, Hanash SM, Kucherlapati R. Comprehensive proteome analysis of an Apc mouse model uncovers proteins associated with intestinal tumorigenesis. Cancer Prev Res (Phila). 2009 Mar; 2(3):224-33. PMID: 19240248.
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    139. Faça VM, Hanash SM. In-depth proteomics to define the cell surface and secretome of ovarian cancer cells and processes of protein shedding. Cancer Res. 2009 Feb 01; 69(3):728-30. PMID: 19155298.
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    140. Faca V, Wang H, Hanash S. Proteomic global profiling for cancer biomarker discovery. Methods Mol Biol. 2009; 492:309-20. PMID: 19241042.
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    141. Souchelnytskyi S, Hanash S. Focus on breast cancer proteomics. Proteomics Clin Appl. 2009 Jan; 3(1):5. PMID: 21136931.
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    142. Menon R, Zhang Q, Zhang Y, Fermin D, Bardeesy N, DePinho RA, Lu C, Hanash SM, Omenn GS, States DJ. Identification of novel alternative splice isoforms of circulating proteins in a mouse model of human pancreatic cancer. Cancer Res. 2009 Jan 01; 69(1):300-9. PMID: 19118015.
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    143. Wang H, Hanash S. Electrospray mass spectrometry for quantitative plasma proteome analysis. Methods Mol Biol. 2009; 564:227-42. PMID: 19544026.
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    144. May D, Liu Y, Law W, Fitzgibbon M, Wang H, Hanash S, McIntosh M. Peptide sequence confidence in accurate mass and time analysis and its use in complex proteomics experiments. J Proteome Res. 2008 Dec; 7(12):5148-56. PMID: 19367719.
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    145. Vaisocherová H, Faca VM, Taylor AD, Hanash S, Jiang S. Comparative study of SPR and ELISA methods based on analysis of CD166/ALCAM levels in cancer and control human sera. Biosens Bioelectron. 2009 Mar 15; 24(7):2143-8. PMID: 19157844.
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    146. Fang Q, Strand A, Law W, Faca VM, Fitzgibbon MP, Hamel N, Houle B, Liu X, May DH, Poschmann G, Roy L, Stühler K, Ying W, Zhang J, Zheng Z, Bergeron JJ, Hanash S, He F, Leavitt BR, Meyer HE, Qian X, McIntosh MW. Brain-specific proteins decline in the cerebrospinal fluid of humans with Huntington disease. Mol Cell Proteomics. 2009 Mar; 8(3):451-66. PMID: 18984577.
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    147. McIntosh M, Anderson G, Drescher C, Hanash S, Urban N, Brown P, Gambhir SS, Coukos G, Laird PW, Nelson B, Palmer C. Ovarian cancer early detection claims are biased. Clin Cancer Res. 2008 Nov 15; 14(22):7574; author reply 7577-9. PMID: 18948385.
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    148. Liu Y, Kuick R, Hanash S, Richardson B. DNA methylation inhibition increases T cell KIR expression through effects on both promoter methylation and transcription factors. Clin Immunol. 2009 Feb; 130(2):213-24. PMID: 18945643.
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    149. Paczesny S, Krijanovski OI, Braun TM, Choi SW, Clouthier SG, Kuick R, Misek DE, Cooke KR, Kitko CL, Weyand A, Bickley D, Jones D, Whitfield J, Reddy P, Levine JE, Hanash SM, Ferrara JL. A biomarker panel for acute graft-versus-host disease. Blood. 2009 Jan 08; 113(2):273-8. PMID: 18832652.
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    150. Creighton CJ, Nagaraja AK, Hanash SM, Matzuk MM, Gunaratne PH. A bioinformatics tool for linking gene expression profiling results with public databases of microRNA target predictions. RNA. 2008 Nov; 14(11):2290-6. PMID: 18812437.
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    151. Qiu J, Choi G, Li L, Wang H, Pitteri SJ, Pereira-Faca SR, Krasnoselsky AL, Randolph TW, Omenn GS, Edelstein C, Barnett MJ, Thornquist MD, Goodman GE, Brenner DE, Feng Z, Hanash SM. Occurrence of autoantibodies to annexin I, 14-3-3 theta and LAMR1 in prediagnostic lung cancer sera. J Clin Oncol. 2008 Nov 01; 26(31):5060-6. PMID: 18794547.
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    152. Luethy R, Kessner DE, Katz JE, Maclean B, Grothe R, Kani K, Faça V, Pitteri S, Hanash S, Agus DB, Mallick P. Precursor-ion mass re-estimation improves peptide identification on hybrid instruments. J Proteome Res. 2008 Sep; 7(9):4031-9. PMID: 18707148.
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    153. Kim YS, Son OL, Lee JY, Kim SH, Oh S, Lee YS, Kim CH, Yoo JS, Lee JH, Miyoshi E, Taniguchi N, Hanash SM, Yoo HS, Ko JH. Lectin precipitation using phytohemagglutinin-L(4) coupled to avidin-agarose for serological biomarker discovery in colorectal cancer. Proteomics. 2008 Aug; 8(16):3229-35. PMID: 18633972.
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    154. Shedden K, Taylor JM, Enkemann SA, Tsao MS, Yeatman TJ, Gerald WL, Eschrich S, Jurisica I, Giordano TJ, Misek DE, Chang AC, Zhu CQ, Strumpf D, Hanash S, Shepherd FA, Ding K, Seymour L, Naoki K, Pennell N, Weir B, Verhaak R, Ladd-Acosta C, Golub T, Gruidl M, Sharma A, Szoke J, Zakowski M, Rusch V, Kris M, Viale A, Motoi N, Travis W, Conley B, Seshan VE, Meyerson M, Kuick R, Dobbin KK, Lively T, Jacobson JW, Beer DG. Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med. 2008 Aug; 14(8):822-7. PMID: 18641660.
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    155. Faça VM, Ventura AP, Fitzgibbon MP, Pereira-Faça SR, Pitteri SJ, Green AE, Ireton RC, Zhang Q, Wang H, O'Briant KC, Drescher CW, Schummer M, McIntosh MW, Knudsen BS, Hanash SM. Proteomic analysis of ovarian cancer cells reveals dynamic processes of protein secretion and shedding of extra-cellular domains. PLoS One. 2008 Jun 18; 3(6):e2425. PMID: 18560578.
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    156. Faca VM, Song KS, Wang H, Zhang Q, Krasnoselsky AL, Newcomb LF, Plentz RR, Gurumurthy S, Redston MS, Pitteri SJ, Pereira-Faca SR, Ireton RC, Katayama H, Glukhova V, Phanstiel D, Brenner DE, Anderson MA, Misek D, Scholler N, Urban ND, Barnett MJ, Edelstein C, Goodman GE, Thornquist MD, McIntosh MW, DePinho RA, Bardeesy N, Hanash SM. A mouse to human search for plasma proteome changes associated with pancreatic tumor development. PLoS Med. 2008 Jun 10; 5(6):e123. PMID: 18547137.
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    157. Zhang Q, Menon R, Deutsch EW, Pitteri SJ, Faca VM, Wang H, Newcomb LF, Depinho RA, Bardeesy N, Dinulescu D, Hung KE, Kucherlapati R, Jacks T, Politi K, Aebersold R, Omenn GS, States DJ, Hanash SM. A mouse plasma peptide atlas as a resource for disease proteomics. Genome Biol. 2008; 9(6):R93. PMID: 18522751.
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    158. Wang H, Hanash SM. Increased throughput and reduced carryover of mass spectrometry-based proteomics using a high-efficiency nonsplit nanoflow parallel dual-column capillary HPLC system. J Proteome Res. 2008 Jul; 7(7):2743-55. PMID: 18512973.
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    159. Ehrlich M, Sanchez C, Shao C, Nishiyama R, Kehrl J, Kuick R, Kubota T, Hanash SM. ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. Autoimmunity. 2008 May; 41(4):253-71. PMID: 18432406.
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    160. Krasnoselsky AL, Faca VM, Pitteri SJ, Zhang Q, Hanash SM. Isoform analysis of LC-MS/MS data from multidimensional fractionation of the serum proteome. J Proteome Res. 2008 Jun; 7(6):2546-52. PMID: 18419151.
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    161. Hanash SM, Pitteri SJ, Faca VM. Mining the plasma proteome for cancer biomarkers. Nature. 2008 Apr 03; 452(7187):571-9. PMID: 18385731.
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    162. Pitteri SJ, Faca VM, Kelly-Spratt KS, Kasarda AE, Wang H, Zhang Q, Newcomb L, Krasnoselsky A, Paczesny S, Choi G, Fitzgibbon M, McIntosh MW, Kemp CJ, Hanash SM. Plasma proteome profiling of a mouse model of breast cancer identifies a set of up-regulated proteins in common with human breast cancer cells. J Proteome Res. 2008 Apr; 7(4):1481-9. PMID: 18311905.
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    163. Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Björling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, Bustelo XR, Cagney G, Cantin GT, Cardasis HL, Celis JE, Chaerkady R, Chu F, Cole PA, Costello CE, Cotter RJ, Crockett D, DeLany JP, De Marzo AM, DeSouza LV, Deutsch EW, Dransfield E, Drewes G, Droit A, Dunn MJ, Elenitoba-Johnson K, Ewing RM, Van Eyk J, Faca V, Falkner J, Fang X, Fenselau C, Figeys D, Gagné P, Gelfi C, Gevaert K, Gimble JM, Gnad F, Goel R, Gromov P, Hanash SM, Hancock WS, Harsha HC, Hart G, Hays F, He F, Hebbar P, Helsens K, Hermeking H, Hide W, Hjernø K, Hochstrasser DF, Hofmann O, Horn DM, Hruban RH, Ibarrola N, James P, Jensen ON, Jensen PH, Jung P, Kandasamy K, Kheterpal I, Kikuno RF, Korf U, Körner R, Kuster B, Kwon MS, Lee HJ, Lee YJ, Lefevre M, Lehvaslaiho M, Lescuyer P, Levander F, Lim MS, Löbke C, Loo JA, Mann M, Martens L, Martinez-Heredia J, McComb M, McRedmond J, Mehrle A, Menon R, Miller CA, Mischak H, Mohan SS, Mohmood R, Molina H, Moran MF, Morgan JD, Moritz R, Morzel M, Muddiman DC, Nalli A, Navarro JD, Neubert TA, Ohara O, Oliva R, Omenn GS, Oyama M, Paik YK, Pennington K, Pepperkok R, Periaswamy B, Petricoin EF, Poirier GG, Prasad TS, Purvine SO, Rahiman BA, Ramachandran P, Ramachandra YL, Rice RH, Rick J, Ronnholm RH, Salonen J, Sanchez JC, Sayd T, Seshi B, Shankari K, Sheng SJ, Shetty V, Shivakumar K, Simpson RJ, Sirdeshmukh R, Siu KW, Smith JC, Smith RD, States DJ, Sugano S, Sullivan M, Superti-Furga G, Takatalo M, Thongboonkerd V, Trinidad JC, Uhlen M, Vandekerckhove J, Vasilescu J, Veenstra TD, Vidal-Taboada JM, Vihinen M, Wait R, Wang X, Wiemann S, Wu B, Xu T, Yates JR, Zhong J, Zhou M, Zhu Y, Zurbig P, Pandey A. Human Proteinpedia enables sharing of human protein data. Nat Biotechnol. 2008 Feb; 26(2):164-7. PMID: 18259167.
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    164. Pereira-Faca SR, Kuick R, Puravs E, Zhang Q, Krasnoselsky AL, Phanstiel D, Qiu J, Misek DE, Hinderer R, Tammemagi M, Landi MT, Caporaso N, Pfeiffer R, Edelstein C, Goodman G, Barnett M, Thornquist M, Brenner D, Hanash SM. Identification of 14-3-3 theta as an antigen that induces a humoral response in lung cancer. Cancer Res. 2007 Dec 15; 67(24):12000-6. PMID: 18089831.
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    165. Madoz-Gúrpide J, Kuick R, Wang H, Misek DE, Hanash SM. Integral protein microarrays for the identification of lung cancer antigens in sera that induce a humoral immune response. Mol Cell Proteomics. 2008 Feb; 7(2):268-81. PMID: 17916591.
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    166. Pitteri SJ, Hanash SM. Proteomic approaches for cancer biomarker discovery in plasma. Expert Rev Proteomics. 2007 Oct; 4(5):589-90. PMID: 17941811.
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    167. Faca V, Hanash S. In-depth quantitative proteomics for pancreatic cancer biomarker discovery. Expert Opin Med Diagn. 2007 Sep; 1(1):81-9. PMID: 23489270.
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    168. Hanash S. It takes a village to develop biomarkers. J Proteome Res. 2007 Sep; 6(9):3362. PMID: 17924484.
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    169. Faca V, Krasnoselsky A, Hanash S. Innovative proteomic approaches for cancer biomarker discovery. Biotechniques. 2007 Sep; 43(3):279, 281-3, 285. PMID: 17907570.
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    170. Faca V, Pitteri SJ, Newcomb L, Glukhova V, Phanstiel D, Krasnoselsky A, Zhang Q, Struthers J, Wang H, Eng J, Fitzgibbon M, McIntosh M, Hanash S. Contribution of protein fractionation to depth of analysis of the serum and plasma proteomes. J Proteome Res. 2007 Sep; 6(9):3558-65. PMID: 17696519.
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    171. Forrester S, Qiu J, Mangold L, Partin A, Misek D, Phinney B, Whitten D, Andrews P, Diamandis E, Omenn GS, Hanash S, Haab BB. An experimental strategy for quantitative analysis of the humoral immune response to prostate cancer antigens using natural protein microarrays. Proteomics Clin Appl. 2007 May; 1(5):494-505. PMID: 21136701.
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    172. Wu R, Hendrix-Lucas N, Kuick R, Zhai Y, Schwartz DR, Akyol A, Hanash S, Misek DE, Katabuchi H, Williams BO, Fearon ER, Cho KR. Mouse model of human ovarian endometrioid adenocarcinoma based on somatic defects in the Wnt/beta-catenin and PI3K/Pten signaling pathways. Cancer Cell. 2007 Apr; 11(4):321-33. PMID: 17418409.
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    173. Kuick R, Misek DE, Monsma DJ, Webb CP, Wang H, Peterson KJ, Pisano M, Omenn GS, Hanash SM. Discovery of cancer biomarkers through the use of mouse models. Cancer Lett. 2007 Apr 28; 249(1):40-8. PMID: 17320282.
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    174. Seliger B, Fedorushchenko A, Brenner W, Ackermann A, Atkins D, Hanash S, Lichtenfels R. Ubiquitin COOH-terminal hydrolase 1: a biomarker of renal cell carcinoma associated with enhanced tumor cell proliferation and migration. Clin Cancer Res. 2007 Jan 01; 13(1):27-37. PMID: 17200335.
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    175. Song K, Hanash S. Unraveling the complex proteome for biomarker discovery in gastrointestinal and liver diseases. Gastroenterology. 2006 Nov; 131(5):1375-8. PMID: 17064703.
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    176. Mannová P, Fang R, Wang H, Deng B, McIntosh MW, Hanash SM, Beretta L. Modification of host lipid raft proteome upon hepatitis C virus replication. Mol Cell Proteomics. 2006 Dec; 5(12):2319-25. PMID: 16943187.
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    177. Gupta A, Williams BR, Hanash SM, Rawwas J. Cellular retinoic acid-binding protein II is a direct transcriptional target of MycN in neuroblastoma. Cancer Res. 2006 Aug 15; 66(16):8100-8. PMID: 16912187.
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    178. Faca V, Coram M, Phanstiel D, Glukhova V, Zhang Q, Fitzgibbon M, McIntosh M, Hanash S. Quantitative analysis of acrylamide labeled serum proteins by LC-MS/MS. J Proteome Res. 2006 Aug; 5(8):2009-18. PMID: 16889424.
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    179. Djuric U, El-Maarri O, Lamb B, Kuick R, Seoud M, Coullin P, Oldenburg J, Hanash S, Slim R. Familial molar tissues due to mutations in the inflammatory gene, NALP7, have normal postzygotic DNA methylation. Hum Genet. 2006 Oct; 120(3):390-5. PMID: 16874523.
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    180. Kubisch CH, Gukovsky I, Lugea A, Pandol SJ, Kuick R, Misek DE, Hanash SM, Logsdon CD. Long-term ethanol consumption alters pancreatic gene expression in rats: a possible connection to pancreatic injury. Pancreas. 2006 Jul; 33(1):68-76. PMID: 16804415.
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    181. Chignard N, Shang S, Wang H, Marrero J, Bréchot C, Hanash S, Beretta L. Cleavage of endoplasmic reticulum proteins in hepatocellular carcinoma: Detection of generated fragments in patient sera. Gastroenterology. 2006 Jun; 130(7):2010-22. PMID: 16762624.
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    182. Giordano TJ, Au AY, Kuick R, Thomas DG, Rhodes DR, Wilhelm KG, Vinco M, Misek DE, Sanders D, Zhu Z, Ciampi R, Hanash S, Chinnaiyan A, Clifton-Bligh RJ, Robinson BG, Nikiforov YE, Koenig RJ. Delineation, functional validation, and bioinformatic evaluation of gene expression in thyroid follicular carcinomas with the PAX8-PPARG translocation. Clin Cancer Res. 2006 Apr 01; 12(7 Pt 1):1983-93. PMID: 16609007.
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    183. States DJ, Omenn GS, Blackwell TW, Fermin D, Eng J, Speicher DW, Hanash SM. Challenges in deriving high-confidence protein identifications from data gathered by a HUPO plasma proteome collaborative study. Nat Biotechnol. 2006 Mar; 24(3):333-8. PMID: 16525410.
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    184. Murdoch S, Djuric U, Mazhar B, Seoud M, Khan R, Kuick R, Bagga R, Kircheisen R, Ao A, Ratti B, Hanash S, Rouleau GA, Slim R. Mutations in NALP7 cause recurrent hydatidiform moles and reproductive wastage in humans. Nat Genet. 2006 Mar; 38(3):300-2. PMID: 16462743.
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    185. Davis MA, Hanash S. High-throughput genomic technology in research and clinical management of breast cancer. Plasma-based proteomics in early detection and therapy. Breast Cancer Res. 2006; 8(6):217. PMID: 17184556.
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    186. Rauch A, Bellew M, Eng J, Fitzgibbon M, Holzman T, Hussey P, Igra M, Maclean B, Lin CW, Detter A, Fang R, Faca V, Gafken P, Zhang H, Whiteaker J, Whitaker J, States D, Hanash S, Paulovich A, McIntosh MW. Computational Proteomics Analysis System (CPAS): an extensible, open-source analytic system for evaluating and publishing proteomic data and high throughput biological experiments. J Proteome Res. 2006 Jan; 5(1):112-21. PMID: 16396501.
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    187. Hong SH, Misek DE, Wang H, Puravs E, Hinderer R, Giordano TJ, Greenson JK, Brenner DE, Simeone DM, Logsdon CD, Hanash SM. Identification of a Specific Vimentin Isoform That Induces an Antibody Response in Pancreatic Cancer. Biomark Insights. 2006; 1:175-183. PMID: 18769604.
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    188. Giordano TJ, Kuick R, Thomas DG, Misek DE, Vinco M, Sanders D, Zhu Z, Ciampi R, Roh M, Shedden K, Gauger P, Doherty G, Thompson NW, Hanash S, Koenig RJ, Nikiforov YE. Molecular classification of papillary thyroid carcinoma: distinct BRAF, RAS, and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis. Oncogene. 2005 Oct 06; 24(44):6646-56. PMID: 16007166.
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    189. Gao WM, Kuick R, Orchekowski RP, Misek DE, Qiu J, Greenberg AK, Rom WN, Brenner DE, Omenn GS, Haab BB, Hanash SM. Distinctive serum protein profiles involving abundant proteins in lung cancer patients based upon antibody microarray analysis. BMC Cancer. 2005 Aug 23; 5:110. PMID: 16117833.
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    190. Misek DE, Kuick R, Wang H, Galchev V, Deng B, Zhao R, Tra J, Pisano MR, Amunugama R, Allen D, Walker AK, Strahler JR, Andrews P, Omenn GS, Hanash SM. A wide range of protein isoforms in serum and plasma uncovered by a quantitative intact protein analysis system. Proteomics. 2005 Aug; 5(13):3343-52. PMID: 16047307.
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    191. Omenn GS, States DJ, Adamski M, Blackwell TW, Menon R, Hermjakob H, Apweiler R, Haab BB, Simpson RJ, Eddes JS, Kapp EA, Moritz RL, Chan DW, Rai AJ, Admon A, Aebersold R, Eng J, Hancock WS, Hefta SA, Meyer H, Paik YK, Yoo JS, Ping P, Pounds J, Adkins J, Qian X, Wang R, Wasinger V, Wu CY, Zhao X, Zeng R, Archakov A, Tsugita A, Beer I, Pandey A, Pisano M, Andrews P, Tammen H, Speicher DW, Hanash SM. Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database. Proteomics. 2005 Aug; 5(13):3226-45. PMID: 16104056.
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    192. Ping P, Vondriska TM, Creighton CJ, Gandhi TK, Yang Z, Menon R, Kwon MS, Cho SY, Drwal G, Kellmann M, Peri S, Suresh S, Gronborg M, Molina H, Chaerkady R, Rekha B, Shet AS, Gerszten RE, Wu H, Raftery M, Wasinger V, Schulz-Knappe P, Hanash SM, Paik YK, Hancock WS, States DJ, Omenn GS, Pandey A. A functional annotation of subproteomes in human plasma. Proteomics. 2005 Aug; 5(13):3506-19. PMID: 16104058.
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    193. Rozek LS, Lipkin SM, Fearon ER, Hanash S, Giordano TJ, Greenson JK, Kuick R, Misek DE, Taylor JM, Douglas JA, Rennert G, Gruber SB. CDX2 polymorphisms, RNA expression, and risk of colorectal cancer. Cancer Res. 2005 Jul 01; 65(13):5488-92. PMID: 15994917.
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    194. Li JY, Kuick R, Thompson RC, Misek DE, Lai YM, Liu YQ, Chai BX, Hanash SM, Gantz I. Arcuate nucleus transcriptome profiling identifies ankyrin repeat and suppressor of cytokine signalling box-containing protein 4 as a gene regulated by fasting in central nervous system feeding circuits. J Neuroendocrinol. 2005 Jun; 17(6):394-404. PMID: 15929745.
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    195. Wang H, Hanash S. Intact-protein based sample preparation strategies for proteome analysis in combination with mass spectrometry. Mass Spectrom Rev. 2005 May-Jun; 24(3):413-26. PMID: 15389852.
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    196. Hinoi T, Gesina G, Akyol A, Kuick R, Hanash S, Giordano TJ, Gruber SB, Fearon ER. CDX2-regulated expression of iron transport protein hephaestin in intestinal and colonic epithelium. Gastroenterology. 2005 Apr; 128(4):946-61. PMID: 15825077.
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    197. Shedden KA, Kshirsagar MP, Schwartz DR, Wu R, Yu H, Misek DE, Hanash S, Katabuchi H, Ellenson LH, Fearon ER, Cho KR. Histologic type, organ of origin, and Wnt pathway status: effect on gene expression in ovarian and uterine carcinomas. Clin Cancer Res. 2005 Mar 15; 11(6):2123-31. PMID: 15788657.
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    198. Williams TM, Williams ME, Kuick R, Misek D, McDonagh K, Hanash S, Innis JW. Candidate downstream regulated genes of HOX group 13 transcription factors with and without monomeric DNA binding capability. Dev Biol. 2005 Mar 15; 279(2):462-80. PMID: 15733672.
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    199. Creighton CJ, Bromberg-White JL, Misek DE, Monsma DJ, Brichory F, Kuick R, Giordano TJ, Gao W, Omenn GS, Webb CP, Hanash SM. Analysis of tumor-host interactions by gene expression profiling of lung adenocarcinoma xenografts identifies genes involved in tumor formation. Mol Cancer Res. 2005 Mar; 3(3):119-29. PMID: 15798092.
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    200. Shedden K, Chen W, Kuick R, Ghosh D, Macdonald J, Cho KR, Giordano TJ, Gruber SB, Fearon ER, Taylor JM, Hanash S. Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data. BMC Bioinformatics. 2005 Feb 10; 6:26. PMID: 15705192.
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    201. Wang H, Clouthier SG, Galchev V, Misek DE, Duffner U, Min CK, Zhao R, Tra J, Omenn GS, Ferrara JL, Hanash SM. Intact-protein-based high-resolution three-dimensional quantitative analysis system for proteome profiling of biological fluids. Mol Cell Proteomics. 2005 May; 4(5):618-25. PMID: 15703445.
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    202. Steel LF, Haab BB, Hanash SM. Methods of comparative proteomic profiling for disease diagnostics. J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Feb 05; 815(1-2):275-84. PMID: 15652816.
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    203. Dobbin KK, Beer DG, Meyerson M, Yeatman TJ, Gerald WL, Jacobson JW, Conley B, Buetow KH, Heiskanen M, Simon RM, Minna JD, Girard L, Misek DE, Taylor JM, Hanash S, Naoki K, Hayes DN, Ladd-Acosta C, Enkemann SA, Viale A, Giordano TJ. Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays. Clin Cancer Res. 2005 Jan 15; 11(2 Pt 1):565-72. PMID: 15701842.
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    204. Misek DE, Kuick R, Hanash SM, Logsdon CD. Oligonucleotide-directed microarray gene profiling of pancreatic adenocarcinoma. Methods Mol Med. 2005; 103:175-87. PMID: 15542906.
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    205. Nam MJ, Kee MK, Kuick R, Hanash SM. Identification of defensin alpha6 as a potential biomarker in colon adenocarcinoma. J Biol Chem. 2005 Mar 04; 280(9):8260-5. PMID: 15613481.
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    206. Marcus B, Arenberg D, Lee J, Kleer C, Chepeha DB, Schmalbach CE, Islam M, Paul S, Pan Q, Hanash S, Kuick R, Merajver SD, Teknos TN. Prognostic factors in oral cavity and oropharyngeal squamous cell carcinoma. Cancer. 2004 Dec 15; 101(12):2779-87. PMID: 15546137.
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    207. Misek DE, Imafuku Y, Hanash SM. Application of proteomic technologies to tumor analysis. Pharmacogenomics. 2004 Dec; 5(8):1129-37. PMID: 15584879.
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    208. Binkley CE, Zhang L, Greenson JK, Giordano TJ, Kuick R, Misek D, Hanash S, Logsdon CD, Simeone DM. The molecular basis of pancreatic fibrosis: common stromal gene expression in chronic pancreatitis and pancreatic adenocarcinoma. Pancreas. 2004 Nov; 29(4):254-63. PMID: 15502640.
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    209. Nakamura K, Aebersold R, Bairoch A, Dunn M, Celis J, Hanash S, Hochstrasser D, Humphrey-Smith I, James P, Klose J, LaBaer J, Langen H, Mann M, Parekh R, Patterson S, Pearce C, Poepstorff P, Simpson RJ, Tomlinson I, Tsugita A, Yates J. [From genome to proteome--aim of human proteomics]. Seikagaku. 2004 Oct; 76(10):1271-4. PMID: 15580857.
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    210. Engstrom LD, Youkilis AS, Gorelick JL, Zheng D, Ackley V, Petroff CA, Benson LQ, Coon MR, Zhu X, Hanash SM, Wechsler DS. Mxi1-0, an alternatively transcribed Mxi1 isoform, is overexpressed in glioblastomas. Neoplasia. 2004 Sep-Oct; 6(5):660-73. PMID: 15548375.
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    211. Girard S, Vossman E, Misek DE, Podevin P, Hanash S, Bréchot C, Beretta L. Hepatitis C virus NS5A-regulated gene expression and signaling revealed via microarray and comparative promoter analyses. Hepatology. 2004 Sep; 40(3):708-18. PMID: 15349911.
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    212. Barnes BJ, Richards J, Mancl M, Hanash S, Beretta L, Pitha PM. Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection. J Biol Chem. 2004 Oct 22; 279(43):45194-207. PMID: 15308637.
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    213. Hong SH, Misek DE, Wang H, Puravs E, Giordano TJ, Greenson JK, Brenner DE, Simeone DM, Logsdon CD, Hanash SM. An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer. Cancer Res. 2004 Aug 01; 64(15):5504-10. PMID: 15289361.
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    214. Hanash S. Integrated global profiling of cancer. Nat Rev Cancer. 2004 08; 4(8):638-44. PMID: 15286743.
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    215. Oelke K, Lu Q, Richardson D, Wu A, Deng C, Hanash S, Richardson B. Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors. Arthritis Rheum. 2004 Jun; 50(6):1850-60. PMID: 15188362.
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    216. Zatkova A, Ullmann R, Rouillard JM, Lamb BJ, Kuick R, Hanash SM, Schnittger S, Schoch C, Fonatsch C, Wimmer K. Distinct sequences on 11q13.5 and 11q23-24 are frequently coamplified with MLL in complexly organized 11q amplicons in AML/MDS patients. Genes Chromosomes Cancer. 2004 Apr; 39(4):263-76. PMID: 14978788.
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    217. Asakawa J, Kuick R, Kodaira M, Nakamura N, Katayama H, Pierce D, Funamoto S, Preston D, Satoh C, Neel JV, Hanash S. A genome scanning approach to assess the genetic effects of radiation in mice and humans. Radiat Res. 2004 Apr; 161(4):380-90. PMID: 15038760.
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    218. Chen G, Wang H, Miller CT, Thomas DG, Gharib TG, Misek DE, Giordano TJ, Orringer MB, Hanash SM, Beer DG. Reduced selenium-binding protein 1 expression is associated with poor outcome in lung adenocarcinomas. J Pathol. 2004 Mar; 202(3):321-9. PMID: 14991897.
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    219. Qiu J, Madoz-Gurpide J, Misek DE, Kuick R, Brenner DE, Michailidis G, Haab BB, Omenn GS, Hanash S. Development of natural protein microarrays for diagnosing cancer based on an antibody response to tumor antigens. J Proteome Res. 2004 Mar-Apr; 3(2):261-7. PMID: 15113102.
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    220. Gharib TG, Chen G, Huang CC, Misek DE, Iannettoni MD, Hanash SM, Orringer MB, Beer DG. Genomic and proteomic analyses of vascular endothelial growth factor and insulin-like growth factor-binding protein 3 in lung adenocarcinomas. Clin Lung Cancer. 2004 Mar; 5(5):307-12. PMID: 15086970.
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    221. Hanash S. Building a foundation for the human proteome: the role of the Human Proteome Organization. J Proteome Res. 2004 Mar-Apr; 3(2):197-9. PMID: 15113094.
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    222. Schmalbach CE, Chepeha DB, Giordano TJ, Rubin MA, Teknos TN, Bradford CR, Wolf GT, Kuick R, Misek DE, Trask DK, Hanash S. Molecular profiling and the identification of genes associated with metastatic oral cavity/pharynx squamous cell carcinoma. Arch Otolaryngol Head Neck Surg. 2004 Mar; 130(3):295-302. PMID: 15023835.
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    223. Cuezva JM, Chen G, Alonso AM, Isidoro A, Misek DE, Hanash SM, Beer DG. The bioenergetic signature of lung adenocarcinomas is a molecular marker of cancer diagnosis and prognosis. Carcinogenesis. 2004 Jul; 25(7):1157-63. PMID: 14963017.
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    224. Zatkova A, Rouillard JM, Hartmann W, Lamb BJ, Kuick R, Eckart M, von Schweinitz D, Koch A, Fonatsch C, Pietsch T, Hanash SM, Wimmer K. Amplification and overexpression of the IGF2 regulator PLAG1 in hepatoblastoma. Genes Chromosomes Cancer. 2004 Feb; 39(2):126-37. PMID: 14695992.
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    225. Hanash S. HUPO initiatives relevant to clinical proteomics. Mol Cell Proteomics. 2004 Apr; 3(4):298-301. PMID: 14747694.
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    226. Imafuku Y, Omenn GS, Hanash S. Proteomics approaches to identify tumor antigen directed autoantibodies as cancer biomarkers. Dis Markers. 2004; 20(3):149-53. PMID: 15502247.
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    227. Hanash S. The emerging field of protein microarrays. Proteomics. 2003 Nov; 3(11):2075. PMID: 14595827.
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    228. Chen J, Mo R, Lescure PA, Misek DE, Hanash S, Rochford R, Hobbs M, Yung RL. Aging is associated with increased T-cell chemokine expression in C57BL/6 mice. J Gerontol A Biol Sci Med Sci. 2003 Nov; 58(11):975-83. PMID: 14630877.
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    229. Shedden KA, Taylor JM, Giordano TJ, Kuick R, Misek DE, Rennert G, Schwartz DR, Gruber SB, Logsdon C, Simeone D, Kardia SL, Greenson JK, Cho KR, Beer DG, Fearon ER, Hanash S. Accurate molecular classification of human cancers based on gene expression using a simple classifier with a pathological tree-based framework. Am J Pathol. 2003 Nov; 163(5):1985-95. PMID: 14578198.
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    230. Nam MJ, Madoz-Gurpide J, Wang H, Lescure P, Schmalbach CE, Zhao R, Misek DE, Kuick R, Brenner DE, Hanash SM. Molecular profiling of the immune response in colon cancer using protein microarrays: occurrence of autoantibodies to ubiquitin C-terminal hydrolase L3. Proteomics. 2003 Nov; 3(11):2108-15. PMID: 14595809.
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    231. Bouwman K, Qiu J, Zhou H, Schotanus M, Mangold LA, Vogt R, Erlandson E, Trenkle J, Partin AW, Misek D, Omenn GS, Haab BB, Hanash S. Microarrays of tumor cell derived proteins uncover a distinct pattern of prostate cancer serum immunoreactivity. Proteomics. 2003 Nov; 3(11):2200-7. PMID: 14595819.
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    232. Chen G, Gharib TG, Wang H, Huang CC, Kuick R, Thomas DG, Shedden KA, Misek DE, Taylor JM, Giordano TJ, Kardia SL, Iannettoni MD, Yee J, Hogg PJ, Orringer MB, Hanash SM, Beer DG. Protein profiles associated with survival in lung adenocarcinoma. Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23):13537-42. PMID: 14573703.
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    233. Jang JH, Hanash S. Profiling of the cell surface proteome. Proteomics. 2003 Oct; 3(10):1947-54. PMID: 14625857.
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    234. Grolleau A, Misek DE, Kuick R, Hanash S, Mulé JJ. Inducible expression of macrophage receptor Marco by dendritic cells following phagocytic uptake of dead cells uncovered by oligonucleotide arrays. J Immunol. 2003 Sep 15; 171(6):2879-88. PMID: 12960310.
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    235. Miller CT, Chen G, Gharib TG, Wang H, Thomas DG, Misek DE, Giordano TJ, Yee J, Orringer MB, Hanash SM, Beer DG. Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas. Oncogene. 2003 Sep 11; 22(39):7950-7. PMID: 12970743.
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    236. van den Boom J, Wolter M, Kuick R, Misek DE, Youkilis AS, Wechsler DS, Sommer C, Reifenberger G, Hanash SM. Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction. Am J Pathol. 2003 Sep; 163(3):1033-43. PMID: 12937144.
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    237. Ji B, Chen XQ, Misek DE, Kuick R, Hanash S, Ernst S, Najarian R, Logsdon CD. Pancreatic gene expression during the initiation of acute pancreatitis: identification of EGR-1 as a key regulator. Physiol Genomics. 2003 Jun 24; 14(1):59-72. PMID: 12709512.
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    238. Creighton C, Kuick R, Misek DE, Rickman DS, Brichory FM, Rouillard JM, Omenn GS, Hanash S. Profiling of pathway-specific changes in gene expression following growth of human cancer cell lines transplanted into mice. Genome Biol. 2003; 4(7):R46. PMID: 12844362.
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    239. Schwartz DR, Wu R, Kardia SL, Levin AM, Huang CC, Shedden KA, Kuick R, Misek DE, Hanash SM, Taylor JM, Reed H, Hendrix N, Zhai Y, Fearon ER, Cho KR. Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas. Cancer Res. 2003 Jun 01; 63(11):2913-22. PMID: 12782598.
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    240. Logsdon CD, Simeone DM, Binkley C, Arumugam T, Greenson JK, Giordano TJ, Misek DE, Kuick R, Hanash S. Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer. Cancer Res. 2003 May 15; 63(10):2649-57. PMID: 12750293.
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    241. Lu Q, Wu A, Ray D, Deng C, Attwood J, Hanash S, Pipkin M, Lichtenheld M, Richardson B. DNA methylation and chromatin structure regulate T cell perforin gene expression. J Immunol. 2003 May 15; 170(10):5124-32. PMID: 12734359.
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    242. Wu R, Lin L, Beer DG, Ellenson LH, Lamb BJ, Rouillard JM, Kuick R, Hanash S, Schwartz DR, Fearon ER, Cho KR. Amplification and overexpression of the L-MYC proto-oncogene in ovarian carcinomas. Am J Pathol. 2003 May; 162(5):1603-10. PMID: 12707044.
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    243. Creighton C, Hanash S, Beer D. Gene expression patterns define pathways correlated with loss of differentiation in lung adenocarcinomas. FEBS Lett. 2003 Apr 10; 540(1-3):167-70. PMID: 12681502.
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    244. Wang H, Hanash S. Multi-dimensional liquid phase based separations in proteomics. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Apr 05; 787(1):11-8. PMID: 12659729.
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    245. Chen G, Gharib TG, Thomas DG, Huang CC, Misek DE, Kuick RD, Giordano TJ, Iannettoni MD, Orringer MB, Hanash SM, Beer DG. Proteomic analysis of eIF-5A in lung adenocarcinomas. Proteomics. 2003 Apr; 3(4):496-504. PMID: 12687616.
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    246. Ichiba T, Teshima T, Kuick R, Misek DE, Liu C, Takada Y, Maeda Y, Reddy P, Williams DL, Hanash SM, Ferrara JL. Early changes in gene expression profiles of hepatic GVHD uncovered by oligonucleotide microarrays. Blood. 2003 Jul 15; 102(2):763-71. PMID: 12663442.
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    247. Hanash S. Disease proteomics. Nature. 2003 Mar 13; 422(6928):226-32. PMID: 12634796.
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    248. Chen G, Wang H, Gharib TG, Huang CC, Thomas DG, Shedden KA, Kuick R, Taylor JM, Kardia SL, Misek DE, Giordano TJ, Iannettoni MD, Orringer MB, Hanash SM, Beer DG. Overexpression of oncoprotein 18 correlates with poor differentiation in lung adenocarcinomas. Mol Cell Proteomics. 2003 Feb; 2(2):107-16. PMID: 12644570.
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    249. Giordano TJ, Thomas DG, Kuick R, Lizyness M, Misek DE, Smith AL, Sanders D, Aljundi RT, Gauger PG, Thompson NW, Taylor JM, Hanash SM. Distinct transcriptional profiles of adrenocortical tumors uncovered by DNA microarray analysis. Am J Pathol. 2003 Feb; 162(2):521-31. PMID: 12547710.
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    250. Mo R, Chen J, Han Y, Bueno-Cannizares C, Misek DE, Lescure PA, Hanash S, Yung RL. T cell chemokine receptor expression in aging. J Immunol. 2003 Jan 15; 170(2):895-904. PMID: 12517955.
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    251. Hanash S. Harnessing immunity for cancer marker discovery. Nat Biotechnol. 2003 Jan; 21(1):37-8. PMID: 12511908.
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    252. Hanash S, Creighton C. Making sense of microarray data to classify cancer. Pharmacogenomics J. 2003; 3(6):308-11. PMID: 14597962.
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    253. Creighton C, Hanash S. Expression of matrix metalloproteinase 9 (MMP-9/gelatinase B) in adenocarcinomas strongly correlated with expression of immune response genes. In Silico Biol. 2003; 3(3):301-11. PMID: 12954092.
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    254. Creighton C, Hanash S. Mining gene expression databases for association rules. Bioinformatics. 2003 Jan; 19(1):79-86. PMID: 12499296.
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    255. Madoz-Gurpide J, Hanash SM. Molecular analysis of cancer using DNA and protein microarrays. Adv Exp Med Biol. 2003; 532:51-8. PMID: 12908549.
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    256. Shin BK, Wang H, Yim AM, Le Naour F, Brichory F, Jang JH, Zhao R, Puravs E, Tra J, Michael CW, Misek DE, Hanash SM. Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function. J Biol Chem. 2003 Feb 28; 278(9):7607-16. PMID: 12493773.
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    257. Moran CJ, Arenberg DA, Huang CC, Giordano TJ, Thomas DG, Misek DE, Chen G, Iannettoni MD, Orringer MB, Hanash S, Beer DG. RANTES expression is a predictor of survival in stage I lung adenocarcinoma. Clin Cancer Res. 2002 Dec; 8(12):3803-12. PMID: 12473593.
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    258. Richards J, Le Naour F, Hanash S, Beretta L. Integrated genomic and proteomic analysis of signaling pathways in dendritic cell differentiation and maturation. Ann N Y Acad Sci. 2002 Dec; 975:91-100. PMID: 12538157.
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    259. Hinoi T, Lucas PC, Kuick R, Hanash S, Cho KR, Fearon ER. CDX2 regulates liver intestine-cadherin expression in normal and malignant colon epithelium and intestinal metaplasia. Gastroenterology. 2002 Nov; 123(5):1565-77. PMID: 12404231.
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    260. Shin BK, Wang H, Hanash S. Proteomics approaches to uncover the repertoire of circulating biomarkers for breast cancer. J Mammary Gland Biol Neoplasia. 2002 Oct; 7(4):407-13. PMID: 12882525.
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    261. Lin L, Miller CT, Contreras JI, Prescott MS, Dagenais SL, Wu R, Yee J, Orringer MB, Misek DE, Hanash SM, Glover TW, Beer DG. The hepatocyte nuclear factor 3 alpha gene, HNF3alpha (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas. Cancer Res. 2002 Sep 15; 62(18):5273-9. PMID: 12234996.
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    262. Tra J, Kondo T, Lu Q, Kuick R, Hanash S, Richardson B. Infrequent occurrence of age-dependent changes in CpG island methylation as detected by restriction landmark genome scanning. Mech Ageing Dev. 2002 Sep; 123(11):1487-503. PMID: 12425956.
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    263. Gharib TG, Chen G, Wang H, Huang CC, Prescott MS, Shedden K, Misek DE, Thomas DG, Giordano TJ, Taylor JM, Kardia S, Yee J, Orringer MB, Hanash S, Beer DG. Proteomic analysis of cytokeratin isoforms uncovers association with survival in lung adenocarcinoma. Neoplasia. 2002 Sep-Oct; 4(5):440-8. PMID: 12192603.
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    264. Misek DE, Chang CL, Kuick R, Hinderer R, Giordano TJ, Beer DG, Hanash SM. Transforming properties of a Q18-->E mutation of the microtubule regulator Op18. Cancer Cell. 2002 Sep; 2(3):217-28. PMID: 12242154.
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    265. Zhu X, Wimmer K, Kuick R, Lamb BJ, Motyka S, Jasty R, Castle VP, Hanash SM. N-myc modulates expression of p73 in neuroblastoma. Neoplasia. 2002 Sep-Oct; 4(5):432-9. PMID: 12192602.
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    266. Schwartz DR, Kardia SL, Shedden KA, Kuick R, Michailidis G, Taylor JM, Misek DE, Wu R, Zhai Y, Darrah DM, Reed H, Ellenson LH, Giordano TJ, Fearon ER, Hanash SM, Cho KR. Gene expression in ovarian cancer reflects both morphology and biological behavior, distinguishing clear cell from other poor-prognosis ovarian carcinomas. Cancer Res. 2002 Aug 15; 62(16):4722-9. PMID: 12183431.
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    267. Wang H, Hanash SM. Contributions of proteome profiling to the molecular analysis of cancer. Technol Cancer Res Treat. 2002 Aug; 1(4):237-46. PMID: 12625782.
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    268. Hanash S. Samir Hanash discusses how HUPO aims to globalize proteomics research (interview by Joanna Owens). Drug Discov Today. 2002 Aug 01; 7(15):797-801. PMID: 12546963.
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    269. Ross SE, Erickson RL, Gerin I, DeRose PM, Bajnok L, Longo KA, Misek DE, Kuick R, Hanash SM, Atkins KB, Andresen SM, Nebb HI, Madsen L, Kristiansen K, MacDougald OA. Microarray analyses during adipogenesis: understanding the effects of Wnt signaling on adipogenesis and the roles of liver X receptor alpha in adipocyte metabolism. Mol Cell Biol. 2002 Aug; 22(16):5989-99. PMID: 12138207.
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    270. Naour FL, Brichory F, Beretta L, Hanash SM. Identification of tumor-associated antigens using proteomics. Technol Cancer Res Treat. 2002 Aug; 1(4):257-62. PMID: 12625784.
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    271. Beer DG, Kardia SL, Huang CC, Giordano TJ, Levin AM, Misek DE, Lin L, Chen G, Gharib TG, Thomas DG, Lizyness ML, Kuick R, Hayasaka S, Taylor JM, Iannettoni MD, Orringer MB, Hanash S. Gene-expression profiles predict survival of patients with lung adenocarcinoma. Nat Med. 2002 Aug; 8(8):816-24. PMID: 12118244.
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    272. Chen G, Gharib TG, Huang CC, Thomas DG, Shedden KA, Taylor JM, Kardia SL, Misek DE, Giordano TJ, Iannettoni MD, Orringer MB, Hanash SM, Beer DG. Proteomic analysis of lung adenocarcinoma: identification of a highly expressed set of proteins in tumors. Clin Cancer Res. 2002 Jul; 8(7):2298-305. PMID: 12114434.
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    273. Hanash S, Celis JE. The Human Proteome Organization: a mission to advance proteome knowledge. Mol Cell Proteomics. 2002 Jun; 1(6):413-4. PMID: 12169681.
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    274. Girard S, Shalhoub P, Lescure P, Sabile A, Misek DE, Hanash S, Bréchot C, Beretta L. An altered cellular response to interferon and up-regulation of interleukin-8 induced by the hepatitis C viral protein NS5A uncovered by microarray analysis. Virology. 2002 Apr 10; 295(2):272-83. PMID: 12033786.
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    275. Grolleau A, Bowman J, Pradet-Balade B, Puravs E, Hanash S, Garcia-Sanz JA, Beretta L. Global and specific translational control by rapamycin in T cells uncovered by microarrays and proteomics. J Biol Chem. 2002 Jun 21; 277(25):22175-84. PMID: 11943782.
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    276. Leung JY, Kolligs FT, Wu R, Zhai Y, Kuick R, Hanash S, Cho KR, Fearon ER. Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling. J Biol Chem. 2002 Jun 14; 277(24):21657-65. PMID: 11940574.
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    277. Hanash SM, Madoz-Gurpide J, Misek DE. Identification of novel targets for cancer therapy using expression proteomics. Leukemia. 2002 Apr; 16(4):478-85. PMID: 11960325.
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    278. Chen G, Gharib TG, Huang CC, Taylor JM, Misek DE, Kardia SL, Giordano TJ, Iannettoni MD, Orringer MB, Hanash SM, Beer DG. Discordant protein and mRNA expression in lung adenocarcinomas. Mol Cell Proteomics. 2002 Apr; 1(4):304-13. PMID: 12096112.
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    279. Wimmer K, Zhu Xx XX, Rouillard JM, Ambros PF, Lamb BJ, Kuick R, Eckart M, Weinhäusl A, Fonatsch C, Hanash SM. Combined restriction landmark genomic scanning and virtual genome scans identify a novel human homeobox gene, ALX3, that is hypermethylated in neuroblastoma. Genes Chromosomes Cancer. 2002 Mar; 33(3):285-94. PMID: 11807986.
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    280. Le Naour F, Brichory F, Misek DE, Bréchot C, Hanash SM, Beretta L. A distinct repertoire of autoantibodies in hepatocellular carcinoma identified by proteomic analysis. Mol Cell Proteomics. 2002 Mar; 1(3):197-203. PMID: 12096119.
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    281. Hanash SM, Beretta LM. Operomics: integrated genomic and proteomic profiling of cells and tissues. Brief Funct Genomic Proteomic. 2002 Feb; 1(1):10-22. PMID: 15251063.
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    282. Li JY, Lescure PA, Misek DE, Lai YM, Chai BX, Kuick R, Thompson RC, Demo RM, Kurnit DM, Michailidis G, Hanash SM, Gantz I. Food deprivation-induced expression of minoxidil sulfotransferase in the hypothalamus uncovered by microarray analysis. J Biol Chem. 2002 Mar 15; 277(11):9069-76. PMID: 11782476.
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    283. Hanash SM, Bobek MP, Rickman DS, Williams T, Rouillard JM, Kuick R, Puravs E. Integrating cancer genomics and proteomics in the post-genome era. Proteomics. 2002 Jan; 2(1):69-75. PMID: 11788993.
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    284. Hanash SM. Global profiling of gene expression in cancer using genomics and proteomics. Curr Opin Mol Ther. 2001 Dec; 3(6):538-45. PMID: 11804268.
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    285. Ehrlich M, Buchanan KL, Tsien F, Jiang G, Sun B, Uicker W, Weemaes CM, Smeets D, Sperling K, Belohradsky BH, Tommerup N, Misek DE, Rouillard JM, Kuick R, Hanash SM. DNA methyltransferase 3B mutations linked to the ICF syndrome cause dysregulation of lymphogenesis genes. Hum Mol Genet. 2001 Dec 01; 10(25):2917-31. PMID: 11741835.
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    286. Hanash S, Petricoin E, Liotta L. A meeting of minds in proteomics. Proteomics. 2001 Dec; 1(12):1475-8. PMID: 11822353.
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    287. Brichory F, Beer D, Le Naour F, Giordano T, Hanash S. Proteomics-based identification of protein gene product 9.5 as a tumor antigen that induces a humoral immune response in lung cancer. Cancer Res. 2001 Nov 01; 61(21):7908-12. PMID: 11691811.
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    288. Erson AE, Niell BL, DeMers SK, Rouillard JM, Hanash SM, Petty EM. Overexpressed genes/ESTs and characterization of distinct amplicons on 17q23 in breast cancer cells. Neoplasia. 2001 Nov-Dec; 3(6):521-6. PMID: 11774034.
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    289. Chang CL, Hora N, Huberman N, Hinderer R, Kukuruga M, Hanash SM. Oncoprotein 18 levels and phosphorylation mediate megakaryocyte polyploidization in human erythroleukemia cells. Proteomics. 2001 Nov; 1(11):1415-23. PMID: 11922601.
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    290. Le Naour F, Misek DE, Krause MC, Deneux L, Giordano TJ, Scholl S, Hanash SM. Proteomics-based identification of RS/DJ-1 as a novel circulating tumor antigen in breast cancer. Clin Cancer Res. 2001 Nov; 7(11):3328-35. PMID: 11705844.
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    291. Madoz-Gúrpide J, Wang H, Misek DE, Brichory F, Hanash SM. Protein based microarrays: a tool for probing the proteome of cancer cells and tissues. Proteomics. 2001 Oct; 1(10):1279-87. PMID: 11721639.
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    292. Srinivas PR, Srivastava S, Hanash S, Wright GL. Proteomics in early detection of cancer. Clin Chem. 2001 Oct; 47(10):1901-11. PMID: 11568117.
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    293. Giordano TJ, Shedden KA, Schwartz DR, Kuick R, Taylor JM, Lee N, Misek DE, Greenson JK, Kardia SL, Beer DG, Rennert G, Cho KR, Gruber SB, Fearon ER, Hanash S. Organ-specific molecular classification of primary lung, colon, and ovarian adenocarcinomas using gene expression profiles. Am J Pathol. 2001 Oct; 159(4):1231-8. PMID: 11583950.
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    294. Oh JM, Brichory F, Puravs E, Kuick R, Wood C, Rouillard JM, Tra J, Kardia S, Beer D, Hanash S. A database of protein expression in lung cancer. Proteomics. 2001 Oct; 1(10):1303-19. PMID: 11721642.
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    295. Waghray A, Feroze F, Schober MS, Yao F, Wood C, Puravs E, Krause M, Hanash S, Chen YQ. Identification of androgen-regulated genes in the prostate cancer cell line LNCaP by serial analysis of gene expression and proteomic analysis. Proteomics. 2001 Oct; 1(10):1327-38. PMID: 11721644.
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    296. Hanash S. Mining the cancer proteome. Proteomics. 2001 Oct; 1(10):1189-90. PMID: 11721630.
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    297. Rickman DS, Bobek MP, Misek DE, Kuick R, Blaivas M, Kurnit DM, Taylor J, Hanash SM. Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis. Cancer Res. 2001 Sep 15; 61(18):6885-91. PMID: 11559565.
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    298. Verma M, Wright GL, Hanash SM, Gopal-Srivastava R, Srivastava S. Proteomic approaches within the NCI early detection research network for the discovery and identification of cancer biomarkers. Ann N Y Acad Sci. 2001 Sep; 945:103-15. PMID: 11708463.
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    299. Bidon N, Brichory F, Hanash S, Bourguet P, Dazord L, Le Pennec JP. Two messenger RNAs and five isoforms for Po66-CBP, a galectin-8 homolog in a human lung carcinoma cell line. Gene. 2001 Aug 22; 274(1-2):253-62. PMID: 11675018.
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    300. Brichory FM, Misek DE, Yim AM, Krause MC, Giordano TJ, Beer DG, Hanash SM. An immune response manifested by the common occurrence of annexins I and II autoantibodies and high circulating levels of IL-6 in lung cancer. Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17):9824-9. PMID: 11504947.
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    301. Rouillard JM, Erson AE, Kuick R, Asakawa J, Wimmer K, Muleris M, Petty EM, Hanash S. Virtual genome scan: a tool for restriction landmark-based scanning of the human genome. Genome Res. 2001 Aug; 11(8):1453-9. PMID: 11483587.
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    302. Yung R, Ray D, Eisenbraun JK, Deng C, Attwood J, Eisenbraun MD, Johnson K, Miller RA, Hanash S, Richardson B. Unexpected effects of a heterozygous dnmt1 null mutation on age-dependent DNA hypomethylation and autoimmunity. J Gerontol A Biol Sci Med Sci. 2001 Jun; 56(6):B268-76. PMID: 11382789.
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    303. Hanash S. 2-D or not 2-D--is there a future for 2-D gels in proteomics? Insights from the York proteomics meeting. Proteomics. 2001 May; 1(5):635-7. PMID: 11678032.
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    304. Le Naour F, Hohenkirk L, Grolleau A, Misek DE, Lescure P, Geiger JD, Hanash S, Beretta L. Profiling changes in gene expression during differentiation and maturation of monocyte-derived dendritic cells using both oligonucleotide microarrays and proteomics. J Biol Chem. 2001 May 25; 276(21):17920-31. PMID: 11279020.
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    305. Rickman DS, Tyagi R, Zhu XX, Bobek MP, Song S, Blaivas M, Misek DE, Israel MA, Kurnit DM, Ross DA, Kish PE, Hanash SM. The gene for the axonal cell adhesion molecule TAX-1 is amplified and aberrantly expressed in malignant gliomas. Cancer Res. 2001 Mar 01; 61(5):2162-8. PMID: 11280781.
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    306. Deng C, Kaplan MJ, Yang J, Ray D, Zhang Z, McCune WJ, Hanash SM, Richardson BC. Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients. Arthritis Rheum. 2001 Feb; 44(2):397-407. PMID: 11229472.
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    307. Charrin S, Le Naour F, Oualid M, Billard M, Faure G, Hanash SM, Boucheix C, Rubinstein E. The major CD9 and CD81 molecular partner. Identification and characterization of the complexes. J Biol Chem. 2001 Apr 27; 276(17):14329-37. PMID: 11278880.
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    308. Hiyama E, Hiyama K, Ohtsu K, Yamaoka H, Fukuba I, Matsuura Y, Yokoyama T. Biological characteristics of neuroblastoma with partial deletion in the short arm of chromosome 1. Med Pediatr Oncol. 2001 Jan; 36(1):67-74. PMID: 11464909.
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    309. Hanash S, Brichory F, Beer D. A proteomic approach to the identification of lung cancer markers. Dis Markers. 2001; 17(4):295-300. PMID: 11790896.
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    310. Wimmer K, Zhu XX, Lamb BJ, Kuick R, Ambros P, Kovar H, Thoraval D, Elkahloun A, Meltzer P, Hanash SM. Two-dimensional DNA electrophoresis identifies novel CpG islands frequently coamplified with MYCN in neuroblastoma. Med Pediatr Oncol. 2001 Jan; 36(1):75-9. PMID: 11464910.
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    311. Lin L, Prescott MS, Zhu Z, Singh P, Chun SY, Kuick RD, Hanash SM, Orringer MB, Glover TW, Beer DG. Identification and characterization of a 19q12 amplicon in esophageal adenocarcinomas reveals cyclin E as the best candidate gene for this amplicon. Cancer Res. 2000 Dec 15; 60(24):7021-7. PMID: 11156406.
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    312. Grolleau A, Kaplan MJ, Hanash SM, Beretta L, Richardson B. Impaired translational response and increased protein kinase PKR expression in T cells from lupus patients. J Clin Invest. 2000 Dec; 106(12):1561-8. PMID: 11120763.
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    313. Prasannan L, Misek DE, Hinderer R, Michon J, Geiger JD, Hanash SM. Identification of beta-tubulin isoforms as tumor antigens in neuroblastoma. Clin Cancer Res. 2000 Oct; 6(10):3949-56. PMID: 11051243.
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    314. Hanash SM. Operomics: molecular analysis of tissues from DNA to RNA to protein. Clin Chem Lab Med. 2000 Sep; 38(9):805-13. PMID: 11097332.
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    315. Hanash SM. Biomedical applications of two-dimensional electrophoresis using immobilized pH gradients: current status. Electrophoresis. 2000 Apr; 21(6):1202-9. PMID: 10786892.
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    316. Wall DB, Kachman MT, Gong S, Hinderer R, Parus S, Misek DE, Hanash SM, Lubman DM. Isoelectric focusing nonporous RP HPLC: a two-dimensional liquid-phase separation method for mapping of cellular proteins with identification using MALDI-TOF mass spectrometry. Anal Chem. 2000 Mar 15; 72(6):1099-111. PMID: 10740846.
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    317. Kondo T, Bobek MP, Kuick R, Lamb B, Zhu X, Narayan A, Bourc'his D, Viegas-Péquignot E, Ehrlich M, Hanash SM. Whole-genome methylation scan in ICF syndrome: hypomethylation of non-satellite DNA repeats D4Z4 and NBL2. Hum Mol Genet. 2000 Mar 01; 9(4):597-604. PMID: 10699183.
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    318. Lin L, Aggarwal S, Glover TW, Orringer MB, Hanash S, Beer DG. A minimal critical region of the 8p22-23 amplicon in esophageal adenocarcinomas defined using sequence tagged site-amplification mapping and quantitative polymerase chain reaction includes the GATA-4 gene. Cancer Res. 2000 Mar 01; 60(5):1341-7. PMID: 10728696.
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    319. Zhu X, Deng C, Kuick R, Yung R, Lamb B, Neel JV, Richardson B, Hanash S. Analysis of human peripheral blood T cells and single-cell-derived T cell clones uncovers extensive clonal CpG island methylation heterogeneity throughout the genome. Proc Natl Acad Sci U S A. 1999 Jul 06; 96(14):8058-63. PMID: 10393947.
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    320. Schickle H, Lamb BJ, Hanash SM. Horizontal two-dimensional electrophoresis of complex DNA samples using precast gel systems. Electrophoresis. 1999 Jun; 20(6):1233-8. PMID: 10380763.
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    321. Oh JM, Hanash SM, Teichroew D. Mining protein data from two-dimensional gels: tools for systematic post-planned analyses. Electrophoresis. 1999 Apr-May; 20(4-5):766-74. PMID: 10344246.
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    322. Soldes OS, Kuick RD, Thompson IA, Hughes SJ, Orringer MB, Iannettoni MD, Hanash SM, Beer DG. Differential expression of Hsp27 in normal oesophagus, Barrett's metaplasia and oesophageal adenocarcinomas. Br J Cancer. 1999 Feb; 79(3-4):595-603. PMID: 10027336.
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    323. Ferbus D, Fléchon A, Muleris M, Li Y, Hanash S, Terris B, Hammel P, Pibouin L, Dutrillaux B, Goubin G. Amplification and over-expression of OZF, a gene encoding a zinc finger protein, in human pancreatic carcinomas. Int J Cancer. 1999 Jan 29; 80(3):369-72. PMID: 9935176.
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    324. Wimmer K, Zhu XX, Lamb BJ, Kuick R, Ambros PF, Kovar H, Thoraval D, Motyka S, Alberts JR, Hanash SM. Co-amplification of a novel gene, NAG, with the N-myc gene in neuroblastoma. Oncogene. 1999 Jan 07; 18(1):233-8. PMID: 9926938.
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    325. Jin X, Chen Y, Lubman DM, Misek D, Hanash SM. Capillary electrophoresis/tandem mass spectrometry for analysis of proteins from two-dimensional sodium dodecyl sulfate polyacrylamide gel electrophoresis. Rapid Commun Mass Spectrom. 1999; 13(23):2327-34. PMID: 10567930.
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    326. Chen Y, Jin X, Misek D, Hinderer R, Hanash SM, Lubman DM. Identification of proteins from two-dimensional gel electrophoresis of human erythroleukemia cells using capillary high performance liquid chromatography/electrospray-ion trap-reflectron time-of-flight mass spectrometry with two-dimensional topographic map analysis of in-gel tryptic digest products. Rapid Commun Mass Spectrom. 1999; 13(19):1907-16. PMID: 10487937.
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    327. Hughes SJ, Glover TW, Zhu XX, Kuick R, Thoraval D, Orringer MB, Beer DG, Hanash S. A novel amplicon at 8p22-23 results in overexpression of cathepsin B in esophageal adenocarcinoma. Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21):12410-5. PMID: 9770500.
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    328. Curtis LJ, Li Y, Gerbault-Seureau M, Kuick R, Dutrillaux AM, Goubin G, Fawcett J, Cram S, Dutrillaux B, Hanash S, Muleris M. Amplification of DNA sequences from chromosome 19q13.1 in human pancreatic cell lines. Genomics. 1998 Oct 01; 53(1):42-55. PMID: 9787076.
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    329. Deng C, Yang J, Scott J, Hanash S, Richardson BC. Role of the ras-MAPK signaling pathway in the DNA methyltransferase response to DNA hypomethylation. Biol Chem. 1998 Aug-Sep; 379(8-9):1113-20. PMID: 9792444.
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    330. Hanash SM, Teichroew D. Mining the human proteome: experience with the human lymphoid protein database. Electrophoresis. 1998 Aug; 19(11):2004-9. PMID: 9740061.
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    331. Almeida A, Zhu XX, Vogt N, Tyagi R, Muleris M, Dutrillaux AM, Dutrillaux B, Ross D, Malfoy B, Hanash S. GAC1, a new member of the leucine-rich repeat superfamily on chromosome band 1q32.1, is amplified and overexpressed in malignant gliomas. Oncogene. 1998 Jun 11; 16(23):2997-3002. PMID: 9662332.
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    332. Beretta L, Singer NG, Hinderer R, Gingras AC, Richardson B, Hanash SM, Sonenberg N. Differential regulation of translation and eIF4E phosphorylation during human thymocyte maturation. J Immunol. 1998 Apr 01; 160(7):3269-73. PMID: 9531283.
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    333. Melhem R, Hailat N, Kuick R, Hanash SM. Quantitative analysis of Op18 phosphorylation in childhood acute leukemia. Leukemia. 1997 Oct; 11(10):1690-5. PMID: 9324290.
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    334. Diaz LA, Friedman AW, He X, Kuick RD, Hanash SM, Fox DA. Monocyte-dependent regulation of T lymphocyte activation through CD98. Int Immunol. 1997 Sep; 9(9):1221-31. PMID: 9310825.
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    335. Yang J, Deng C, Hemati N, Hanash SM, Richardson BC. Effect of mitogenic stimulation and DNA methylation on human T cell DNA methyltransferase expression and activity. J Immunol. 1997 Aug 01; 159(3):1303-9. PMID: 9233626.
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    336. Bradford CR, Zhu S, Poore J, Fisher SG, Beals TF, Thoraval D, Hanash SM, Carey TE, Wolf GT. p53 mutation as a prognostic marker in advanced laryngeal carcinoma. Department of Veterans Affairs Laryngeal Cancer Cooperative Study Group. Arch Otolaryngol Head Neck Surg. 1997 Jun; 123(6):605-9. PMID: 9193221.
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    337. Wimmer K, Thoraval D, Kuick R, Lamb BJ, Hanash SM. Identification of amplifications, deletions and methylation changes in cancer by means of two-dimensional analysis of genomic digests: application to neuroblastoma. Biochem Soc Trans. 1997 Feb; 25(1):262-7. PMID: 9056881.
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    338. Tsukiyama-Kohara K, Vidal SM, Gingras AC, Glover TW, Hanash SM, Heng H, Sonenberg N. Tissue distribution, genomic structure, and chromosome mapping of mouse and human eukaryotic initiation factor 4E-binding proteins 1 and 2. Genomics. 1996 Dec 15; 38(3):353-63. PMID: 8975712.
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    339. Wimmer K, Thoraval D, Asakawa J, Kuick R, Kodaira M, Lamb B, Fawcett J, Glover T, Cram S, Hanash S. Two-dimensional separation and cloning of chromosome 1 NotI-EcoRV-derived genomic fragments. Genomics. 1996 Dec 01; 38(2):124-32. PMID: 8954793.
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    340. Thoraval D, Asakawa J, Wimmer K, Kuick R, Lamb B, Richardson B, Ambros P, Glover T, Hanash S. Demethylation of repetitive DNA sequences in neuroblastoma. Genes Chromosomes Cancer. 1996 Dec; 17(4):234-44. PMID: 8946205.
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    341. Wimmer K, Kuick R, Thoraval D, Hanash SM. Two-dimensional separations of the genome and proteome of neuroblastoma cells. Electrophoresis. 1996 Nov; 17(11):1741-51. PMID: 8982607.
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    342. Kuick R, Asakawa J, Neel JV, Kodaira M, Satoh C, Thoraval D, Gonzalez IL, Hanash SM. Studies of the inheritance of human ribosomal DNA variants detected in two-dimensional separations of genomic restriction fragments. Genetics. 1996 Sep; 144(1):307-16. PMID: 8878694.
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    343. Hanash SM. A role for chromosome 1 in colorectal cancer. Gastroenterology. 1996 Jul; 111(1):250-2. PMID: 8698208.
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    344. Satoh C, Takahashi N, Asakawa J, Kodaira M, Kuick R, Hanash SM, Neel JV. Genetic analysis of children of atomic bomb survivors. Environ Health Perspect. 1996 May; 104 Suppl 3:511-9. PMID: 8781374.
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    345. Thoraval D, Asakawa J, Kodaira M, Chang C, Radany E, Kuick R, Lamb B, Richardson B, Neel JV, Glover T, Hanash S. A methylated human 9-kb repetitive sequence on acrocentric chromosomes is homologous to a subtelomeric repeat in chimpanzees. Proc Natl Acad Sci U S A. 1996 Apr 30; 93(9):4442-7. PMID: 8633086.
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    346. Beretta L, Gabbay M, Berger R, Hanash SM, Sonenberg N. Expression of the protein kinase PKR in modulated by IRF-1 and is reduced in 5q- associated leukemias. Oncogene. 1996 Apr 04; 12(7):1593-6. PMID: 8622878.
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    347. Chang CL, Strahler JR, Thoraval DH, Qian MG, Hinderer R, Hanash SM. A nucleoside diphosphate kinase A (nm23-H1) serine 120-->glycine substitution in advanced stage neuroblastoma affects enzyme stability and alters protein-protein interaction. Oncogene. 1996 Feb 01; 12(3):659-67. PMID: 8637723.
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    348. Qian MG, Zheng K, Chen Y, Chang CL, Hanash SM, Lubman DM. Capillary liquid chromatography coupled with an ion trap storage/reflectron time-of-flight mass spectrometer for structural confirmation of three recombinant protein isoforms. Rapid Commun Mass Spectrom. 1996; 10(9):1079-87. PMID: 8755237.
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    349. Sullivan KA, Castle VP, Hanash SM, Feldman EL. Insulin-like growth factor II in the pathogenesis of human neuroblastoma. Am J Pathol. 1995 Dec; 147(6):1790-8. PMID: 7495303.
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    350. Hailat NQ, Hanash SM. A technique for identification of cellular proteins by western immunoblotting and immunoautoradiography of 2-D PAGE. Indian J Biochem Biophys. 1995 Oct; 32(5):240-4. PMID: 8713743.
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    351. Vila LM, Haftel HM, Park HS, Lin MS, Romzek NC, Hanash SM, Holoshitz J. Expansion of mycobacterium-reactive gamma delta T cells by a subset of memory helper T cells. Infect Immun. 1995 Apr; 63(4):1211-7. PMID: 7890374.
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    352. Asakawa J, Kuick R, Neel JV, Kodaira M, Satoh C, Hanash SM. Quantitative and qualitative genetic variation in two-dimensional DNA gels of human lymphocytoid cell lines. Electrophoresis. 1995 Feb; 16(2):241-52. PMID: 7774565.
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    353. Hailata N, Johnson R, al-Bagdadi F, Hanash S. Proliferating cell nuclear antigen expression in sheep infected with bovine leukemia virus. Vet Immunol Immunopathol. 1995 Feb; 44(3-4):211-22. PMID: 7747402.
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    354. Kuick R, Asakawa J, Neel JV, Satoh C, Hanash SM. High yield of restriction fragment length polymorphisms in two-dimensional separations of human genomic DNA. Genomics. 1995 Jan 20; 25(2):345-53. PMID: 7789966.
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    355. Haftel HM, Chang Y, Hinderer R, Hanash SM, Holoshitz J. Induction of the autoantigen proliferating cell nuclear antigen in T lymphocytes by a mycobacterial antigen. J Clin Invest. 1994 Oct; 94(4):1365-72. PMID: 7929811.
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    356. Asakawa J, Kuick R, Neel JV, Kodaira M, Satoh C, Hanash SM. Genetic variation detected by quantitative analysis of end-labeled genomic DNA fragments. Proc Natl Acad Sci U S A. 1994 Sep 13; 91(19):9052-6. PMID: 7916459.
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    357. Chang CL, Zhu XX, Thoraval DH, Ungar D, Rawwas J, Hora N, Strahler JR, Hanash SM, Radany E. Nm23-H1 mutation in neuroblastoma. Nature. 1994 Aug 04; 370(6488):335-6. PMID: 8047138.
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    358. Ungar DR, Hailat N, Strahler JR, Kuick RD, Brodeur GM, Seeger RC, Reynolds CP, Hanash SM. Hsp27 expression in neuroblastoma: correlation with disease stage. J Natl Cancer Inst. 1994 May 18; 86(10):780-4. PMID: 8169976.
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    359. Hanash SM, Beretta L, Barcroft CL, Sheldon S, Glover TW, Ungar D, Sonenberg N. Mapping of the gene for interferon-inducible dsRNA-dependent protein kinase to chromosome region 2p21-22: a site of rearrangements in myeloproliferative disorders. Genes Chromosomes Cancer. 1993 Sep; 8(1):34-7. PMID: 7691157.
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    360. Wang YK, Liao PC, Allison J, Gage DA, Andrews PC, Lubman DM, Hanash SM, Strahler JR. Phorbol 12-myristate 13-acetate-induced phosphorylation of Op18 in Jurkat T cells. Identification of phosphorylation sites by matrix-assisted laser desorption ionization mass spectrometry. J Biol Chem. 1993 Jul 05; 268(19):14269-77. PMID: 8314790.
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    361. Strahler JR, Zhu XX, Hora N, Wang YK, Andrews PC, Roseman NA, Neel JV, Turka L, Hanash SM. Maturation stage and proliferation-dependent expression of dUTPase in human T cells. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):4991-5. PMID: 8389461.
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    362. Hanash SM, Strahler JR, Chan Y, Kuick R, Teichroew D, Neel JV, Hailat N, Keim DR, Gratiot-Deans J, Ungar D, et al. Data base analysis of protein expression patterns during T-cell ontogeny and activation. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3314-8. PMID: 8475073.
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    363. Turka LA, Gratiot-Deans J, Keim D, Bandukwala R, Green J, Strahler J, Hanash SM. Elevated proliferating cell nuclear antigen levels in immature thymocytes. Dissociation from cell cycle progression. J Immunol. 1993 Apr 01; 150(7):2746-52. PMID: 8095955.
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    364. Keim DR, Hailat N, Kuick R, Reynolds CP, Brodeur GM, Seeger RC, Hanash SM. PCNA levels in neuroblastoma are increased in tumors with an amplified N-myc gene and in metastatic stage tumors. Clin Exp Metastasis. 1993 Jan; 11(1):83-90. PMID: 8093685.
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    365. Gratiot-Deans J, Keim D, Strahler JR, Turka LA, Hanash S. Differential expression of Op18 phosphoprotein during human thymocyte maturation. J Clin Invest. 1992 Oct; 90(4):1576-81. PMID: 1401087.
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    366. Strahler JR, Hailat N, Lamb BJ, Rogers KP, Underhill JA, Melhem RF, Keim DR, Zhu X, Kuick RD, Fox DA, et al. Activation of resting peripheral blood lymphocytes through the T cell receptor induces rapid phosphorylation of Op18. J Immunol. 1992 Aug 15; 149(4):1191-8. PMID: 1500712.
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    367. Kuick RD, Neel JV, Strahler JR, Chu EH, Bargal R, Fox DA, Hanash SM. Similarity of spontaneous germinal and in vitro somatic cell mutation rates in humans: implications for carcinogenesis and for the role of exogenous factors in "spontaneous" germinal mutagenesis. Proc Natl Acad Sci U S A. 1992 Aug 01; 89(15):7036-40. PMID: 1495998.
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    368. Richardson BC, Strahler JR, Pivirotto TS, Quddus J, Bayliss GE, Gross LA, O'Rourke KS, Powers D, Hanash SM, Johnson MA. Phenotypic and functional similarities between 5-azacytidine-treated T cells and a T cell subset in patients with active systemic lupus erythematosus. Arthritis Rheum. 1992 Jun; 35(6):647-62. PMID: 1376122.
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    369. Strahler JR, Lamb BJ, Ungar DR, Fox DA, Hanash SM. Cell cycle progression is associated with distinct patterns of phosphorylation of Op18. Biochem Biophys Res Commun. 1992 May 29; 185(1):197-203. PMID: 1376116.
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    370. Keim D, Hailat N, Melhem R, Zhu XX, Lascu I, Veron M, Strahler J, Hanash SM. Proliferation-related expression of p19/nm23 nucleoside diphosphate kinase. J Clin Invest. 1992 Mar; 89(3):919-24. PMID: 1311721.
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    371. Kuick RD, Skolnick MM, Hanash SM, Neel JV. A two-dimensional electrophoresis-related laboratory information processing system: spot matching. Electrophoresis. 1991 Oct; 12(10):736-46. PMID: 1802691.
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    372. Ali I, Chan Y, Kuick R, Teichroew D, Hanash SM. Implementation of a two-dimensional electrophoresis-related laboratory information processing system: database aspects. Electrophoresis. 1991 Oct; 12(10):747-61. PMID: 1802692.
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    373. Melhem RF, Strahler JR, Hailat N, Zhu XX, Hanash SM. Involvement of OP18 in cell proliferation. Biochem Biophys Res Commun. 1991 Sep 30; 179(3):1649-55. PMID: 1930203.
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    374. Melhem RF, Zhu XX, Hailat N, Strahler JR, Hanash SM. Characterization of the gene for a proliferation-related phosphoprotein (oncoprotein 18) expressed in high amounts in acute leukemia. J Biol Chem. 1991 Sep 25; 266(27):17747-53. PMID: 1917919.
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    375. Görg A, Postel W, Friedrich C, Kuick R, Strahler JR, Hanash SM. Temperature-dependent spot positional variability in two-dimensional polypeptide patterns. Electrophoresis. 1991 Sep; 12(9):653-8. PMID: 1752246.
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    376. Hanash SM, Strahler JR, Neel JV, Hailat N, Melhem R, Keim D, Zhu XX, Wagner D, Gage DA, Watson JT. Highly resolving two-dimensional gels for protein sequencing. Proc Natl Acad Sci U S A. 1991 Jul 01; 88(13):5709-13. PMID: 2062849.
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    377. Hailat N, Keim DR, Melhem RF, Zhu XX, Eckerskorn C, Brodeur GM, Reynolds CP, Seeger RC, Lottspeich F, Strahler JR, et al. High levels of p19/nm23 protein in neuroblastoma are associated with advanced stage disease and with N-myc gene amplification. J Clin Invest. 1991 Jul; 88(1):341-5. PMID: 2056128.
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    378. Strahler JR, Kuick R, Hanash SM. Diminished phosphorylation of a heat shock protein (HSP 27) in infant acute lymphoblastic leukemia. Biochem Biophys Res Commun. 1991 Feb 28; 175(1):134-42. PMID: 1998499.
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    379. Bielinska A, Baier L, Hailat N, Strahler JR, Nabel GJ, Hanash S. Expression of a novel nuclear protein in activated and in tat-I expressing T cells. J Immunol. 1991 Feb 01; 146(3):1031-6. PMID: 1988491.
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    380. Richardson B, Scheinbart L, Strahler J, Gross L, Hanash S, Johnson M. Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis. Arthritis Rheum. 1990 Nov; 33(11):1665-73. PMID: 2242063.
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    381. Hailat N, Strahler J, Melhem R, Zhu XX, Brodeur G, Seeger RC, Reynolds CP, Hanash S. N-myc gene amplification in neuroblastoma is associated with altered phosphorylation of a proliferation related polypeptide (Op18). Oncogene. 1990 Nov; 5(11):1615-8. PMID: 2267130.
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    382. Keim D, Hailat N, Hodge D, Hanash SM. Proliferating cell nuclear antigen expression in childhood acute leukemia. Blood. 1990 Sep 01; 76(5):985-90. PMID: 1975505.
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    383. Ferrari AC, Seuanez HN, Hanash SM, Atweh GF. A gene that encodes for a leukemia-associated phosphoprotein (p18) maps to chromosome bands 1p35-36.1. Genes Chromosomes Cancer. 1990 Jul; 2(2):125-9. PMID: 2278968.
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    384. Strahler JR, Kuick R, Eckerskorn C, Lottspeich F, Richardson BC, Fox DA, Stoolman LM, Hanson CA, Nichols D, Tueche HJ, et al. Identification of two related markers for common acute lymphoblastic leukemia as heat shock proteins. J Clin Invest. 1990 Jan; 85(1):200-7. PMID: 2295696.
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    385. Zhu XX, Kozarsky K, Strahler JR, Eckerskorn C, Lottspeich F, Melhem R, Lowe J, Fox DA, Hanash SM, Atweh GF. Molecular cloning of a novel human leukemia-associated gene. Evidence of conservation in animal species. J Biol Chem. 1989 Aug 25; 264(24):14556-60. PMID: 2760073.
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    386. Hanash SM, Strahler JR. Advances in two-dimensional electrophoresis. Nature. 1989 Feb 02; 337(6206):485-6. PMID: 2915694.
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    387. Hanash SM, Kuick R, Strahler J, Richardson B, Reaman G, Stoolman L, Hanson C, Nichols D, Tueche HJ. Identification of a cellular polypeptide that distinguishes between acute lymphoblastic leukemia in infants and in older children. Blood. 1989 Feb; 73(2):527-32. PMID: 2917188.
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    388. Hanash SM, Kuick R, Nichols D, Stoolman L. Quantitative analysis of a new marker for common acute lymphoblastic leukemia detected by two-dimensional electrophoresis. Dis Markers. 1988 Oct-Dec; 6(4):209-20. PMID: 2976630.
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    389. Hanash SM, Strahler JR, Kuick R, Chu EH, Nichols D. Identification of a polypeptide associated with the malignant phenotype in acute leukemia. J Biol Chem. 1988 Sep 15; 263(26):12813-5. PMID: 3417633.
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    390. Richardson B, Cornacchia E, Golbus J, Maybaum J, Strahler J, Hanash S. N-acetylprocainamide is a less potent inducer of T cell autoreactivity than procainamide. Arthritis Rheum. 1988 Aug; 31(8):995-9. PMID: 2457378.
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    391. Chu EH, Boehnke M, Hanash SM, Kuick RD, Lamb BJ, Neel JV, Niezgoda W, Pivirotto S, Sundling G. Estimation of mutation rates based on the analysis of polypeptide constituents of cultured human lymphoblastoid cells. Genetics. 1988 Jul; 119(3):693-703. PMID: 3402732.
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    392. Robertson PL, Aldrich MS, Hanash SM, Goldstein GW. Stroke associated with obstructive sleep apnea in a child with sickle cell anemia. Ann Neurol. 1988 Jun; 23(6):614-6. PMID: 3408243.
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    393. Kuick RD, Hanash SM, Strahler JR. Somatic mutation studies in human lymphoid cells: the detectability of quantitative genetic variants in two-dimensional gels. Electrophoresis. 1988 Apr; 9(4):192-8. PMID: 3234354.
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    394. Cornacchia E, Golbus J, Maybaum J, Strahler J, Hanash S, Richardson B. Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity. J Immunol. 1988 Apr 01; 140(7):2197-200. PMID: 3258330.
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    395. Strahler JR, Hanash SM, Somerlot L, Bjellqvist B, Görg A. Effect of salt on the performance of immobilized pH gradient isoelectric focusing gels. Electrophoresis. 1988 Feb; 9(2):74-80. PMID: 3234340.
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    396. Görg A, Postel W, Günther S, Weser J, Strahler JR, Hanash SM, Somerlot L, Kuick R. Approach to stationary two-dimensional pattern: influence of focusing time and immobiline/carrier ampholytes concentrations. Electrophoresis. 1988 Jan; 9(1):37-46. PMID: 2466646.
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    397. Hanash SM, Boehnke M, Chu EH, Neel JV, Kuick RD. Nonrandom distribution of structural mutants in ethylnitrosourea-treated cultured human lymphoblastoid cells. Proc Natl Acad Sci U S A. 1988 Jan; 85(1):165-9. PMID: 3422414.
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    398. Schneider J, Erickson RP, Hanash S. Mouse testicular protein variants, including tubulin, detected by isoelectrofocusing two-dimensional gel electrophoresis. Genet Res. 1987 Dec; 50(3):225-33. PMID: 3443294.
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    399. Strahler JR, Rosenblum BB, Hanash SM. Identification and characterization of a human transthyretin variant. Biochem Biophys Res Commun. 1987 Oct 14; 148(1):471-7. PMID: 3675594.
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    400. Boerwinkle E, Visvikis S, Welsh D, Steinmetz J, Hanash SM, Sing CF. The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability, and covariability of cholesterol, betalipoprotein, and triglycerides in a sample of unrelated individuals. Am J Med Genet. 1987 Jul; 27(3):567-82. PMID: 3631131.
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    401. Hanash SM, Chu EH, Kuick R, Skolnick M, Neel J, Strahler J, Pivirotto S, Niezgoda W. Detection of human somatic cell structural gene mutations by two-dimensional electrophoresis. Proteins. 1987; 2(1):13-9. PMID: 3328857.
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    402. Hanash SM, Baier LJ, Welch D, Kuick R, Galteau M. Genetic variants detected among 106 lymphocyte polypeptides observed in two-dimensional gels. Am J Hum Genet. 1986 Sep; 39(3):317-28. PMID: 3766538.
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    403. Cossu G, Manca M, Strahler JR, Hanash SM, Righetti PG. Detection of electrophoretically silent mutations by immobilized pH gradients. J Chromatogr. 1986 Jun 27; 361:223-9. PMID: 3733954.
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    404. Hanash SM, Baier LJ. Two-dimensional gel electrophoresis of cellular proteins reveals myeloid origin of blasts in two children with otherwise undifferentiated leukemia. Cancer. 1986 Apr 15; 57(8):1539-43. PMID: 3456254.
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    405. Hanash SM, Neel JV, Baier LJ, Rosenblum BB, Niezgoda W, Markel D. Genetic analysis of thirty-three platelet polypeptides detected in two-dimensional polyacrylamide gels. Am J Hum Genet. 1986 Mar; 38(3):352-60. PMID: 3953575.
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    406. Hanash SM, Baier LJ, McCurry L, Schwartz SA. Lineage-related polypeptide markers in acute lymphoblastic leukemia detected by two-dimensional gel electrophoresis. Proc Natl Acad Sci U S A. 1986 Feb; 83(3):807-11. PMID: 3484825.
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    407. Kuick R, Boerwinkle E, Hanash SM, Sing CF. A statistical analysis of spot variation using the two-dimensional polyacrylamide gel electrophoresis. Comput Biomed Res. 1986 Feb; 19(1):90-102. PMID: 3948498.
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    408. Neel JV, Baier L, Hanash S, Erickson RP. Frequency of polymorphisms for alleles encoding for liver proteins of domesticated mice. J Hered. 1985 Sep-Oct; 76(5):314-20. PMID: 4056362.
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    409. Rosenblum BB, Strahler JR, Hanash SM, Whitten CF, Butkunas-Puskorius R, Roberts A. Peripheral blood erythroid progenitors from patients with sickle cell anemia: HPLC separation of hemoglobins and the effect of a HbF switching factor. Prog Clin Biol Res. 1985; 191:397-410. PMID: 2413478.
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    410. Hanash SM, Gagnon M, Seeger RC, Baier L. Analysis of neuroblastoma cell proteins using two-dimensional electrophoresis. Prog Clin Biol Res. 1985; 175:261-8. PMID: 3991732.
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    411. Aster JC, Brewer GJ, Hanash SM, Maisel H. Band 4.1-like proteins of the bovine lens. Effects of differentiation, distribution and extraction characteristics. Biochem J. 1984 Dec 01; 224(2):609-16. PMID: 6517866.
      View in: PubMed
    412. Rosenblum BB, Neel JV, Hanash SM, Joseph JL, Yew N. Identification of genetic variants in erythrocyte lysate by two-dimensional gel electrophoresis. Am J Hum Genet. 1984 May; 36(3):601-12. PMID: 6203403.
      View in: PubMed
    413. Baier LJ, Hanash SM, Erickson RP. Mice homozygous for chromosomal deletions at the albino locus region lack specific polypeptides in two-dimensional gels. Proc Natl Acad Sci U S A. 1984 Apr; 81(7):2132-6. PMID: 6585792.
      View in: PubMed
    414. Aster JC, Rosenblum BB, Brewer GJ, Hanash SM. Analysis of protein 4.1 structural variation using 2-dimensional polyacrylamide gel electrophoresis. Prog Clin Biol Res. 1984; 159:73-88. PMID: 6382326.
      View in: PubMed
    415. Gupta SP, Hanash SM. Separation of hemoglobin types by cation-exchange high-performance liquid chromatography. Anal Biochem. 1983 Oct 01; 134(1):117-21. PMID: 6660481.
      View in: PubMed
    416. Strahler JR, Rosenblum BB, Hanash S, Butkunas R. Separation of transferrin types in human plasma by anion-exchange high-performance liquid chromatography. J Chromatogr. 1983 Aug 26; 266:281-91. PMID: 6630354.
      View in: PubMed
    417. Strahler JR, Rosenbloom BB, Hanash SM. A silent, neutral substitution detected by reverse-phase high-performance liquid chromatography: hemoglobin Beirut. Science. 1983 Aug 26; 221(4613):860-2. PMID: 6879181.
      View in: PubMed
    418. Rosenblum BB, Neel JV, Hanash SM. Two-dimensional electrophoresis of plasma polypeptides reveals "high" heterozygosity indices. Proc Natl Acad Sci U S A. 1983 Aug; 80(16):5002-6. PMID: 6576372.
      View in: PubMed
    419. Amanullah A, Hanash S, Bunnell K, Strahler J, Rucknagel DL, Ferruci SJ. Cord blood screening for hemoglobin disorders by high-performance liquid chromatography. Anal Biochem. 1982 Jul 01; 123(2):402-7. PMID: 7125213.
      View in: PubMed
    420. Hanash SM, Tubergen DG, Heyn RM, Neel JV, Sandy L, Stevens GS, Rosenblum BB, Krzesicki RF. Two-dimensional gel electrophoresis of cell proteins in childhood leukemia, with silver staining: a preliminary report. Clin Chem. 1982 Apr; 28(4 Pt 2):1026-30. PMID: 6951652.
      View in: PubMed
    421. Rosenblum BB, Hanash SM, Yew N, Neel JV. Two-dimensional electrophoretic analysis of erythrocyte membranes. Clin Chem. 1982 Apr; 28(4 Pt 2):925-31. PMID: 7074884.
      View in: PubMed
    422. Hanash SM, Kavadella M, Amanullah A, Scheller K, Bunnell K. High performance liquid chromatography of hemoglobins: factors affecting resolution. Prog Clin Biol Res. 1981; 60:53-67. PMID: 6169093.
      View in: PubMed
    423. Hanash SM, Shapiro DN. Separation of human hemoglobins by ion exchange high performance liquid chromatography. Hemoglobin. 1981; 5(2):165-75. PMID: 7216816.
      View in: PubMed
    424. Rucknagel DL, LaDu CS, Reynolds FJ, Hanash SM, Surtshin S, Whitten CW. Immunologic quantification of fetal hemoglobin in sickle cell anemia. Prog Clin Biol Res. 1981; 60:135-47. PMID: 6169089.
      View in: PubMed
    425. Hanash SM, Rucknagel DL. Clinical implications of recent advances in hemoglobin disorders. Med Clin North Am. 1980 Jul; 64(4):775-800. PMID: 6157060.
      View in: PubMed
    426. Winter WP, Hanash SM, Rucknagel DL. Genetic mechanisms contributing to the expression of the human hemoglogin loci. Adv Hum Genet. 1979; 9:229-91, 361-7. PMID: 393093.
      View in: PubMed
    427. Hanash SM, Rucknagel DL, Heidelberger KP, Radin NS. Primary amyloidosis associated with Gaucher's disease. Ann Intern Med. 1978 Nov; 89(5 Pt 1):639-41. PMID: 717933.
      View in: PubMed
    428. Hanash SM, Rucknagel DL. Proteolytic activity in erythrocyte precursors. Proc Natl Acad Sci U S A. 1978 Jul; 75(7):3427-31. PMID: 277945.
      View in: PubMed
    429. Rucknagel DL, Baine RM, Hanash SM, Winter WP. Polymorphism in the number of hemoglobin alpha-chain loci and mechanisms governing the balance of chain synthesis. Prog Clin Biol Res. 1978; 21:63-78. PMID: 662911.
      View in: PubMed
    430. Hanash SM, Winter WP, Rucknagel DL. Synthesis of haemoglobin Wayne in erythroid cells. Nature. 1977 Oct 20; 269(5630):717-9. PMID: 593335.
      View in: PubMed
    431. Proliferating cell nuclear antigen. Leukemia and Lymphoma. 6:459-468.
    432. Defective immunoregulatory functions of leukemic L lymphocytes. Federation Proceedings. 43.
    433. Clinical Applications of Proteomics. 225-241.
    434. Electrophoresis. 8:165-173.
    435. Stability of the hybrid epithelial/mesenchymal phenotype. Oncotarget. 7:27067-27084.
    436. Proteomic profiling of the tumor microenvironment. Genome Medicine. 6.
    437. Integrated global profiling of cancer. Nature Reviews Drug Discovery. 4:9-15.
    438. Biomarkers for Diagnosis and Prognosis of Sinusoidal Obstruction Syndrome after Hematopoietic Cell Transplantation. Biology of Blood and Marrow Transplantation. 21:1739-1745.
    439. The need for an organized effort in proteomics. Current Opinion in Molecular Therapeutics. 4:201-202.
    440. Global strategies for disease detection and treatment. Disease Markers. 17:203-204.
    441. A functional annotation of subproteomes in human plasma. 329-351.
    442. Electrophoresis. 8:122-124.
    443. Increased C-CRK proto-oncogene expression is associated with an aggressive phenotype in lung adenocarcinomas. Oncogene. 22:7950-7957.
    444. Identification of a DNA fragment which escaped methylation inactivation on the X chromosome by two-dimensional electrophoresis of human genomic DNA. Journal of Human Genetics. 41:114.
    445. Proteomics Technologies. 45-55.
    446. Mass spectrometry based proteomics for absolute quantification of proteins from tumor cells. Methods. 81:34-40.
    447. Effect of nigella sativa volatile oil on jurkat t cell leukemia polypeptides. Pharmaceutical Biology. 33:16-20.
    448. Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome. Proceedings of the National Academy of Sciences of the United States of America. 113:E1555-E1564.
    449. Lysyl hydroxylase 2 is secreted by tumor cells and can modify collagen in the extracellular space. Journal of Biological Chemistry. 291:25799-25808.
    450. Diacetylspermine is a novel prediagnostic serum biomarker for non-small-cell lung cancer and has additive performance with pro-surfactant protein B. Journal of Clinical Oncology. 33:3880-3886.
    451. A window on the mammary gland proteome. Journal of Proteome Research. 7:1368.
    452. Electrophoresis. 8:229-234.
    453. Characterization of the ethyl-triphenylphosphonium derivative of model peptides by fast atom bombardment collisionally-activated dissociation tandem mass spectrometry using B/E linked scans. International Journal of Mass Spectrometry and Ion Processes. 111:191-209.
    454. Application of Proteomics to Disease Diagnostics. 285-291.
    455. Serum glycans as risk markers for non-small cell lung cancer. Cancer Prevention Research. 9:317-323.
    456. Trhe Ornstein/Petricoin article reviewed. Oncology. 18:532.
    457. Electrophoresis. 8:199-204.
    458. Deciphering the complexity of the cancer proteome for diagnostic applications. Expert Review of Molecular Diagnostics. 1-7.
    459. Cancer proteomics. 52-57.
    460. EGFR signaling enhances aerobic glycolysis in triple-negative breast cancer cells to promote tumor growth and immune escape. Cancer Research. 76:1284-1296.
    461. Quantitative proteomic analysis of histone modifications in decitabine sensitive and resistant leukemia cell lines. Clinical Proteomics. 13.
    462. Prognostic and functional significance of MAP4K5 in pancreatic cancer. PLoS One. 11.
    463. Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer (Cancer Research (2003) (2649-2657)). Cancer Research. 63:3445.
    464. Cancer-associated fibroblasts induce a collagen cross-link switch in tumor stroma. Molecular Cancer Research. 14:287-295.
    465. Correction to Allele-Specific Reprogramming of Cancer Metabolism by the Long Non-coding RNA CCAT2 [Molecular Cell 61, 520-534, (2016)]. Molecular Cell. 61:640.
    466. Moving forward with clinical proteomics. Clinical Proteomics. 1:3-5.
    467. Immobilized pH gradients. Methods. 3:109-114.
    468. Identification of Tumor Antigen Directed Autoantibodies. 533-547.
    469. Erratum. Journal of Proteome Research. 5:1024.
    470. Translational implications of proteomics. 2959-2964.
    471. Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells. Cell and Bioscience. 1-10.
    472. IL6 blockade reprograms the lung tumor microenvironment to limit the development and progression of K-ras-mutant lung cancer. Cancer Research. 76:3189-3199.
    473. Mining protein data from two-dimensional gels. 186-194.
    474. The emerging role of b cells in tumor immunity. Cancer Research. 76:5591-5601.
    475. Effect of Nigella sativa volatile oil on Jurkat T cell leukemia polypeptides. International Journal of Pharmacognosy. 33:16-20.
    476. A statistical method for detecting differentially expressed SNVs based on next-generation RNA-seq data. Biometrics.
    477. Enrichment strategies in glycomics-based lung cancer biomarker development. Proteomics - Clinical Applications. 7:664-676.
    478. Electrophoresis. 8:45-51.
    479. Proteomic risk markers for coronary heart disease and stroke. Genome Medicine. 5.
    480. An organized effort is needed to fast track the development of cancer biomarkers. Clinical Proteomics. 3:1-2.
    481. MAPRE1 as a plasma biomarker for early-stage colorectal cancer and adenomas. Cancer Prevention Research. 8:1112-1119.
    482. Overview of the HUPO Plasma Proteome Project. 1-35.
    483. Protein and glycomic plasma markers for early detection of adenoma and colon cancer. Gut.
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