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ROBERT J WELLS

TitleProfessor
InstitutionMD Anderson
DepartmentPediatrics
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hanson SJ, Havens PL, Simpson PM, Nugent ML, Wells RG. Intrapleural alteplase decreases parapneumonic effusion volume in children more than saline irrigation. Pediatr Pulmonol. 2015 Dec; 50(12):1328-35. PMID: 25847131.
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    2. Polak U, McIvor E, Dent SY, Wells RD, Napierala M. Expanded complexity of unstable repeat diseases. Biofactors. 2013 Mar-Apr; 39(2):164-75. PMID: 23233240.
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    3. Fernandez CV, Ruccione K, Wells RJ, Long JB, Pelletier W, Hooke MC, Pentz RD, Noll RB, Baker JN, O'Leary M, Reaman G, Adamson PC, Joffe S. Recommendations for the return of research results to study participants and guardians: a report from the Children's Oncology Group. J Clin Oncol. 2012 Dec 20; 30(36):4573-9. PMID: 23109703.
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    4. Wells RJ. The many vs. the few. Hastings Cent Rep. 2012 Sep-Oct; 42(5):7; author reply 8-9. PMID: 23050292.
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    5. Wells RJ. Rationing and reality. Hastings Cent Rep. 2011 Nov-Dec; 41(6):5-6; author reply 6. PMID: 22238893.
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    6. Wells RJ. The American Academy of Pediatrics policy statement--children as hematopoietic stem cell donors. Pediatr Blood Cancer. 2011 Dec 01; 57(6):1086-7; author reply 1088-9. PMID: 21638756.
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    7. Wells RJ. When is state intervention justified? An ethics consult gone bad. Pediatr Blood Cancer. 2010 Jul 01; 54(7):1054; author reply 1055. PMID: 20222018.
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    8. Lin Y, Dent SY, Wilson JH, Wells RD, Napierala M. R loops stimulate genetic instability of CTG.CAG repeats. Proc Natl Acad Sci U S A. 2010 Jan 12; 107(2):692-7. PMID: 20080737.
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    9. Chou AJ, Kleinerman ES, Krailo MD, Chen Z, Betcher DL, Healey JH, Conrad EU, Nieder ML, Weiner MA, Wells RJ, Womer RB, Meyers PA. Addition of muramyl tripeptide to chemotherapy for patients with newly diagnosed metastatic osteosarcoma: a report from the Children's Oncology Group. Cancer. 2009 Nov 15; 115(22):5339-48. PMID: 19637348.
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    10. Wells RJ. The sex kitten of bioethics? Research ethics comes of age. Hastings Cent Rep. 2008 Sep-Oct; 38(5):6-7; author reply 7. PMID: 18947128.
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    11. Amini E, Roffidal T, Lee A, Fuller GN, Mahajan A, Ketonen L, Kobrinsky N, Cairo MS, Wells RJ, Wolff JE. Central neurocytoma responsive to topotecan, ifosfamide, carboplatin. Pediatr Blood Cancer. 2008 Jul; 51(1):137-40. PMID: 18338396.
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    12. Quezada G, Kopp L, Estey E, Wells RJ. All-trans-retinoic acid and arsenic trioxide as initial therapy for acute promyelocytic leukemia. Pediatr Blood Cancer. 2008 Jul; 51(1):133-5. PMID: 18293388.
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    13. Aplenc R, Alonzo TA, Gerbing RB, Lange BJ, Hurwitz CA, Wells RJ, Bernstein I, Buckley P, Krimmel K, Smith FO, Sievers EL, Arceci RJ. Safety and efficacy of gemtuzumab ozogamicin in combination with chemotherapy for pediatric acute myeloid leukemia: a report from the Children's Oncology Group. J Clin Oncol. 2008 May 10; 26(14):2390-3295. PMID: 18467731.
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    14. Wells RJ. Secrecy and integrity in clinical trials. J Clin Oncol. 2008 Feb 01; 26(4):680-2. PMID: 18235131.
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    15. Meyers PA, Schwartz CL, Krailo MD, Healey JH, Bernstein ML, Betcher D, Ferguson WS, Gebhardt MC, Goorin AM, Harris M, Kleinerman E, Link MP, Nadel H, Nieder M, Siegal GP, Weiner MA, Wells RJ, Womer RB, Grier HE. Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival--a report from the Children's Oncology Group. J Clin Oncol. 2008 Feb 01; 26(4):633-8. PMID: 18235123.
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    16. Vannatta K, Gerhardt CA, Wells RJ, Noll RB. Intensity of CNS treatment for pediatric cancer: prediction of social outcomes in survivors. Pediatr Blood Cancer. 2007 Oct 15; 49(5):716-22. PMID: 17096410.
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    17. Wells RJ. Overseeing quality improvement. Hastings Cent Rep. 2007 Jul-Aug; 37(4):6-7; author reply 7-8. PMID: 17847187.
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    18. Wells RJ. The U.S. Department of Medicine. Hastings Cent Rep. 2007 Jan-Feb; 37(1):7; author reply 7. PMID: 17348252.
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    19. Kumar A, Soares H, Wells R, Clarke M, Hozo I, Bleyer A, Reaman G, Chalmers I, Djulbegovic B. Are experimental treatments for cancer in children superior to established treatments? Observational study of randomised controlled trials by the Children's Oncology Group. BMJ. 2005 Dec 03; 331(7528):1295. PMID: 16299015.
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    20. Whitlock JA, Sather HN, Gaynon P, Robison LL, Wells RJ, Trigg M, Heerema NA, Bhatia S. Clinical characteristics and outcome of children with Down syndrome and acute lymphoblastic leukemia: a Children's Cancer Group study. Blood. 2005 Dec 15; 106(13):4043-9. PMID: 16109782.
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    21. Bandyopadhyay S, Hennes H, Gorelick MH, Wells RG, Walsh-Kelly CM. Serum neuron-specific enolase as a predictor of short-term outcome in children with closed traumatic brain injury. Acad Emerg Med. 2005 Aug; 12(8):732-8. PMID: 16079426.
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    22. Alonzo TA, Wells RJ, Woods WG, Lange B, Gerbing RB, Buxton AB, Neudorf S, Sanders J, Smith FO, Feig SA. Postremission therapy for children with acute myeloid leukemia: the children's cancer group experience in the transplant era. Leukemia. 2005 Jun; 19(6):965-70. PMID: 15830007.
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    23. Holdstock D. Wartime medical ethics. Hastings Cent Rep. 2005 May-Jun; 35(3):6-7; author reply 7. PMID: 16092386.
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    24. Wells RJ. Wartime medical ethics. Hastings Cent Rep. 2005 May-Jun; 35(3):7; author reply 7. PMID: 16092388.
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    25. Meyers PA, Schwartz CL, Krailo M, Kleinerman ES, Betcher D, Bernstein ML, Conrad E, Ferguson W, Gebhardt M, Goorin AM, Harris MB, Healey J, Huvos A, Link M, Montebello J, Nadel H, Nieder M, Sato J, Siegal G, Weiner M, Wells R, Wold L, Womer R, Grier H. Osteosarcoma: a randomized, prospective trial of the addition of ifosfamide and/or muramyl tripeptide to cisplatin, doxorubicin, and high-dose methotrexate. J Clin Oncol. 2005 Mar 20; 23(9):2004-11. PMID: 15774791.
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    26. Tiao GM, Bobey N, Allen S, Nieves N, Alonso M, Bucuvalas J, Wells R, Ryckman F. The current management of hepatoblastoma: a combination of chemotherapy, conventional resection, and liver transplantation. J Pediatr. 2005 Feb; 146(2):204-11. PMID: 15689909.
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    27. Wells RJ. Data safety and monitoring boards. N Engl J Med. 2004 Jun 03; 350(23):2423;; author reply 2423. PMID: 15175451.
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    28. Grueneich R, Ris MD, Ball W, Kalinyak KA, Noll R, Vannatta K, Wells R. Relationship of structural magnetic resonance imaging, magnetic resonance perfusion, and other disease factors to neuropsychological outcome in sickle cell disease. J Pediatr Psychol. 2004 Mar; 29(2):83-92. PMID: 15096530.
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    29. Wells RJ. Clinical equipoise: more uncertainty. Hastings Cent Rep. 2003 Nov-Dec; 33(6):4; author reply 4-5. PMID: 14983547.
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    30. Dusenbery KE, Howells WB, Arthur DC, Alonzo T, Lee JW, Kobrinsky N, Barnard DR, Wells RJ, Buckley JD, Lange BJ, Woods WG. Extramedullary leukemia in children with newly diagnosed acute myeloid leukemia: a report from the Children's Cancer Group. J Pediatr Hematol Oncol. 2003 Oct; 25(10):760-8. PMID: 14528097.
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    31. Wells RJ, Adams MT, Alonzo TA, Arceci RJ, Buckley J, Buxton AB, Dusenbery K, Gamis A, Masterson M, Vik T, Warkentin P, Whitlock JA. Mitoxantrone and cytarabine induction, high-dose cytarabine, and etoposide intensification for pediatric patients with relapsed or refractory acute myeloid leukemia: Children's Cancer Group Study 2951. J Clin Oncol. 2003 Aug 01; 21(15):2940-7. PMID: 12885813.
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    32. Wells RG, Havens PL. Intrapleural fibrinolysis for parapneumonic effusion and empyema in children. Radiology. 2003 Aug; 228(2):370-8. PMID: 12893898.
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    33. Meservy JL, Sargent RG, Iyer RR, Chan F, McKenzie GJ, Wells RD, Wilson JH. Long CTG tracts from the myotonic dystrophy gene induce deletions and rearrangements during recombination at the APRT locus in CHO cells. Mol Cell Biol. 2003 May; 23(9):3152-62. PMID: 12697816.
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    34. Wells RJ. Can rationing be fair? Hastings Cent Rep. 2002 Sep-Oct; 32(5):4; author reply 4-5. PMID: 12360772.
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    35. Wells RJ, Arthur DC, Srivastava A, Heerema NA, Le Beau M, Alonzo TA, Buxton AB, Woods WG, Howells WB, Benjamin DR, Betcher DL, Buckley JD, Feig SA, Kim T, Odom LF, Ruymann FB, Smithson WA, Tannous R, Whitt JK, Wolff L, Tjoa T, Lampkin BC. Prognostic variables in newly diagnosed children and adolescents with acute myeloid leukemia: Children's Cancer Group Study 213. Leukemia. 2002 Apr; 16(4):601-7. PMID: 11960339.
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    36. Wells RG, Vetter C, Laud P. Intracranial hemorrhage in children younger than 3 years: prediction of intent. Arch Pediatr Adolesc Med. 2002 Mar; 156(3):252-7. PMID: 11876669.
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    37. Wells RJ, Reid JM, Ames MM, Mares WL, Krailo MD, Seibel NL, Mosher R, Reaman GH, Wiersma SR. Phase I trial of cisplatin and topotecan in children with recurrent solid tumors: Children's Cancer Group Study 0942. J Pediatr Hematol Oncol. 2002 Feb; 24(2):89-93. PMID: 11990712.
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    38. Wells RJ. Heroic surgery. Hastings Cent Rep. 2001 Sep-Oct; 31(5):5-6; author reply 6. PMID: 12974109.
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    39. Wells RJ. Phase I cancer trials: therapeutic research? Hastings Cent Rep. 2001 Jan-Feb; 31(1):4; author reply 5. PMID: 11478096.
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    40. Wells RJ, Woods WG, Buckley JD, Arceci RJ. Therapy for acute myeloid leukemia: intensive timing of induction chemotherapy. Curr Oncol Rep. 2000 Nov; 2(6):524-8. PMID: 11122888.
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    41. Wells R, Sheldon M. Making room for alternatives. Hastings Cent Rep. 2000 May-Jun; 30(3):26-8. PMID: 10862367.
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    42. Wells RJ, Gartside PS, McHenry CL. Ethical issues arising when interim data in clinical trials is restricted to independent data monitoring committees. IRB. 2000 Jan; 22(1):7-11. PMID: 12546010.
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    43. Wells RJ. Secrecy for data monitoring committees: inferior ethics, bad policy. J Clin Oncol. 1998 Jan; 16(1):390-1. PMID: 9440771.
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    44. Whitlock JA, Wells RJ, Hord JD, Janco RL, Greer JP, Gay JC, Edwards JR, McCurley TL, Lukens JN. High-dose cytosine arabinoside and etoposide: an effective regimen without anthracyclines for refractory childhood acute non-lymphocytic leukemia. Leukemia. 1997 Feb; 11(2):185-9. PMID: 9009078.
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    45. Lampkin BC, Wells R. Intrathecal leucovorin after intrathecal methotrexate. J Pediatr Hematol Oncol. 1996 Aug; 18(3):249. PMID: 8689335.
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    46. Ris MD, Kalinyak KA, Ball WS, Noll RB, Wells RJ, Rucknagel D. Pre- and post-stroke MRI and neuropsychological studies in sickle cell disease: a case study. Arch Clin Neuropsychol. 1996; 11(6):481-90. PMID: 14588453.
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    47. Wells RJ, Arndt CA. New agents for treatment of children with acute myelogenous leukemia. J Pediatr Hematol Oncol. 1995 Aug; 17(3):225-33. PMID: 7620921.
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    48. Wells RJ. Phase II window therapy. J Clin Oncol. 1995 Jan; 13(1):302-3. PMID: 7865002.
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    49. Wells RJ, Woods WG, Buckley JD, Odom LF, Benjamin D, Bernstein I, Betcher D, Feig S, Kim T, Ruymann F, et al. Treatment of newly diagnosed children and adolescents with acute myeloid leukemia: a Childrens Cancer Group study. J Clin Oncol. 1994 Nov; 12(11):2367-77. PMID: 7964952.
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    50. Wells RJ. Generic consent for genetic screening. N Engl J Med. 1994 Oct 13; 331(15):1024; author reply 1025. PMID: 8084350.
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    51. Wells RJ, Gold SH, Krill CE, Cornelius AS, Byrd RL, Ruymann FB, Feusner J, White ML, Cairo MS. Cytosine arabinoside and mitoxantrone induction chemotherapy followed by bone marrow transplantation or chemotherapy for relapsed or refractory pediatric acute myeloid leukemia. Leukemia. 1994 Oct; 8(10):1626-30. PMID: 7934157.
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    52. Jones GR, Konsler GK, Dunaway RP, Gold SH, Cooper HA, Wells RJ. Risk factors for recurrent fever after the discontinuation of empiric antibiotic therapy for fever and neutropenia in pediatric patients with a malignancy or hematologic condition. J Pediatr. 1994 May; 124(5 Pt 1):703-8. PMID: 8176555.
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    53. Wells RJ, Odom LF, Gold SH, Feusner J, Krill CE, Waldron P, Moulton TA, Knoppell E, White ML, Cairo MS. Cytosine arabinoside and mitoxantrone treatment of relapsed or refractory childhood leukemia: initial response and relationship to multidrug resistance gene 1. Med Pediatr Oncol. 1994; 22(4):244-9. PMID: 7906380.
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    54. George BA, Yanik G, Wells RJ, Martin LW, Soukup S, Ballard ET, Gartside PS, Lampkin BC. Growth patterns of human neuroblastoma xenografts and their relationship to treatment outcome. Cancer. 1993 Dec 01; 72(11):3331-9. PMID: 8242560.
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    55. Wells RJ, Woods WG, Lampkin BC, Nesbit ME, Lee JW, Buckley JD, Versteeg C, Hammond GD. Impact of high-dose cytarabine and asparaginase intensification on childhood acute myeloid leukemia: a report from the Childrens Cancer Group. J Clin Oncol. 1993 Mar; 11(3):538-45. PMID: 8445429.
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    56. Whitt JK, Hooper SR, Tennison MB, Robertson WT, Gold SH, Burchinal M, Wells R, McMillan C, Whaley RA, Combest J, et al. Neuropsychologic functioning of human immunodeficiency virus-infected children with hemophilia. J Pediatr. 1993 Jan; 122(1):52-9. PMID: 8093486.
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    57. Adamson PC, Balis FM, Miser J, Arndt C, Wells RJ, Gillespie A, Aronson L, Penta JS, Clendeninn NJ, Poplack DG. Pediatric phase I trial, pharmacokinetic study, and limited sampling strategy for piritrexim administered on a low-dose, intermittent schedule. Cancer Res. 1992 Feb 01; 52(3):521-4. PMID: 1732038.
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    58. Kaplan AH, Weber DJ, Davis L, Israel F, Wells RJ. Short courses of antibiotics in selected febrile neutropenic patients. Am J Med Sci. 1991 Dec; 302(6):353-4. PMID: 1772118.
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    59. Miller LP, Pyesmany AF, Wolff LJ, Rogers PC, Siegel SE, Wells RJ, Buckley JD, Hammond GD. Successful reinduction therapy with amsacrine and cyclocytidine in acute nonlymphoblastic leukemia in children. A report from the Childrens Cancer Study Group. Cancer. 1991 May 01; 67(9):2235-40. PMID: 1707336.
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    60. Woods WG, Ruymann FB, Lampkin BC, Buckley JD, Bernstein ID, Srivastava AK, Smithson WA, Benjamin DR, Feig SA, Kim TH, et al. The role of timing of high-dose cytosine arabinoside intensification and of maintenance therapy in the treatment of children with acute nonlymphocytic leukemia. Cancer. 1990 Sep 15; 66(6):1106-13. PMID: 2205352.
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    61. Adamson PC, Balis FM, Miser J, Wells RJ, Bleyer WA, Williams TE, Gillespie A, Penta JS, Clendeninn NJ, Poplack DG. Pediatric phase I trial and pharmacokinetic study of piritrexim administered orally on a five-day schedule. Cancer Res. 1990 Aug 01; 50(15):4464-7. PMID: 2369724.
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    62. Santrach PJ, Askin FB, Wells RJ, Azizkhan RG, Merten DF. Nodular form of bleomycin-related pulmonary injury in patients with osteogenic sarcoma. Cancer. 1989 Aug 15; 64(4):806-11. PMID: 2472865.
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    63. Robison LL, Buckley JD, Daigle AE, Wells R, Benjamin D, Arthur DC, Hammond GD. Maternal drug use and risk of childhood nonlymphoblastic leukemia among offspring. An epidemiologic investigation implicating marijuana (a report from the Childrens Cancer Study Group). Cancer. 1989 May 15; 63(10):1904-11. PMID: 2649219.
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    64. Wells RJ. Diagnostic yield of the autopsy. N Engl J Med. 1988 Oct 20; 319(16):1095-6. PMID: 3173440.
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    65. Lampkin BC, Lange B, Bernstein I, Woods W, Odom L, Wells R, Ruymann F, Feig S, Miller L, Chard R, et al. Biologic characteristics and treatment of acute nonlymphocytic leukemia in children. Report of the ANLL Strategy Group of the Childrens Cancer Study Group. Pediatr Clin North Am. 1988 Aug; 35(4):743-64. PMID: 3047652.
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    66. Fowler MG, Whitt JK, Lallinger RR, Nash KB, Atkinson SS, Wells RJ, McMillan C. Neuropsychologic and academic functioning of children with sickle cell anemia. J Dev Behav Pediatr. 1988 Aug; 9(4):213-20. PMID: 3216001.
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    67. Wells RJ, Weck PK, Baehner RL, Krivit W, Raney RB, Ortega JA, Bernstein IO, Lampkin B, Whisnant JK, Sather HN, et al. Interferon-alpha n1 in children with recurrent acute lymphocytic leukemia: a phase I study of pharmacokinetics and tolerance. J Interferon Res. 1988 Jun; 8(3):309-18. PMID: 3166026.
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    68. Wells RJ, Feusner J, Devney R, Woods WG, Provisor AJ, Cairo MS, Odom LF, Nachman J, Jones GR, Ettinger LJ, et al. Sequential high-dose cytosine arabinoside-asparaginase treatment in advanced childhood leukemia. J Clin Oncol. 1985 Jul; 3(7):998-1004. PMID: 3860629.
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    69. Whitt JK, Wells RJ, Lauria MM, Wilhelm CL, McMillan CW. Cranial radiation in childhood acute lymphocytic leukemia. Neuropsychologic sequelae. Am J Dis Child. 1984 Aug; 138(8):730-6. PMID: 6377873.
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    70. Grill SP, Wells RJ, Cheng YC. Utilization of an immunostaining technique to demonstrate heterogeneity in the content of dihydrofolate reductase in peripheral blast cells from a patient with acute lymphocytic leukemia. Cancer Res. 1984 Mar; 44(3):1252-6. PMID: 6581868.
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    71. Clark RH, Taylor LL, Wells RJ. Congenital juvenile chronic myelogenous leukemia: case report and review. Pediatrics. 1984 Mar; 73(3):324-6. PMID: 6583654.
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    72. Wells RJ, Foster MB, D'Ercole AJ, McMillan CW. The impact of cranial irradiation on the growth of children with acute lymphocytic leukemia. Am J Dis Child. 1983 Jan; 137(1):37-9. PMID: 6336634.
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    73. Yasaka T, Wells RJ, Mantich NM, Boxer LA, Baehner RL. Enrichment by counterpart centrifugal elutriation of human lymphocytes cytotoxic to human tumour cells. Immunology. 1982 Jul; 46(3):613-7. PMID: 7095831.
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    74. Wells RJ, Mascaro K, Young PC, Provisor AJ, Cleary RE, Baehner RL. Normal glucocorticoid receptor numbers in a child with glucocorticoid-resistant relapsed acute lymphocytic leukemia. Am J Pediatr Hematol Oncol. 1981; 3(1):3-7. PMID: 6940460.
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    75. Wells RJ, Mascaro K, Young PC, Cleary RE, Bachner RL. Glucocorticoid receptors in the lymphoblasts of patients with glucocorticoid-resistant childhood acute lymphocytic leukemia. Am J Pediatr Hematol Oncol. 1981; 3(3):259-64. PMID: 6945061.
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    76. Wells RJ, Weetman RM, Baehner RL. The impact of isolated central nervous system relapse following initial complete remission in childhood acute lymphocytic leukemia. J Pediatr. 1980 Sep; 97(3):429-32. PMID: 6931896.
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    77. Wells RJ, Weetman RM, Ballantine TV, Grosfeld JL, Baehner RL. Pulmonary leukemia in children presenting as diffuse interstitial pneumonia. J Pediatr. 1980 Feb; 96(2):262-4. PMID: 6965410.
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    78. Data safety and monitoring boards [7] (multiple letters). New England Journal of Medicine. 350:2423.
    79. A novel trial of topotecan, ifosfamide, and carboplatin (TIC) in children with recurrent solid tumors. Pediatric Blood and Cancer. 62:274-278.
    80. Feasibility study of a novel Experimental induction protocol combining B43-PAP (anti-CD19) immunotoxin with standard induction chemotherapy in children and adolescents with relapsed B-lineage ALL. Journal of Immunotherapy. 38:299-305.
    81. Symptom profiles in children with advanced cancer. Cancer.
    82. Treatment of initial isolated central nervous system (CNS) relapse in patients with childhood acute lymphocytic leukemia (ALL) with previous cranial irradiation (CR). Pediatric Research. 14.
    83. Skeletal, neuromuscular and fitness impairments among children with newly diagnosed acute lymphoblastic leukemia. Leukemia and Lymphoma. 56:1004-1011.
    84. In reply. Journal of Clinical Oncology. 26:3104-3105.
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