Loading...
Header Logo
Keywords
Last Name
Institution

RAGHU KALLURI

TitleProfessor
InstitutionMD Anderson
DepartmentCancer Biology
vCardDownload vCard

    Collapse ORNG Applications 
    Collapse Verify Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. McAndrews KM, LeBleu VS, Kalluri R. SIRT1 Regulates Lysosome Function and Exosome Secretion. Dev Cell. 2019 May 06; 49(3):302-303. PMID: 31063745.
      View in: PubMed
    2. McAndrews KM, Kalluri R. Nischarin Regulates Secretion of Exosomes and Cancer Progression. Cancer Res. 2019 May 01; 79(9):2099-2101. PMID: 31043427.
      View in: PubMed
    3. McAndrews KM, Kalluri R. Mechanisms associated with biogenesis of exosomes in cancer. Mol Cancer. 2019 03 30; 18(1):52. PMID: 30925917.
      View in: PubMed
    4. LeBleu VS, Kalluri R. Exosomes Exercise Inhibition of Anti-Tumor Immunity during Chemotherapy. Immunity. 2019 Mar 19; 50(3):547-549. PMID: 30893584.
      View in: PubMed
    5. Chen Y, Keskin D, Sugimoto H, Kanasaki K, Phillips PE, Bizarro L, Sharpe A, LeBleu VS, Kalluri R. Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis. PLoS Biol. 2018 12; 16(12):e2005907. PMID: 30592710.
      View in: PubMed
    6. Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borràs FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MÁ, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Górecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzás EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekström K, El Andaloussi S, Elie-Caille C, Erdbrügger U, Falcón-Pérez JM, Fatima F, Fish JE, Flores-Bellver M, Försönits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gámez-Valero A, Gardiner C, Gärtner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DC, Görgens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AG, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ, Kornek M, Kosanovic MM, Kovács ÁF, Krämer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lässer C, Laurent LC, Lavieu G, Lázaro-Ibáñez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li IT, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Line A, Linnemannstöns K, Llorente A, Lombard CA, Lorenowicz MJ, Lörincz ÁM, Lötvall J, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SL, Malhi H, Marcilla A, Mariani J, Mariscal J, Martens-Uzunova ES, Martin-Jaular L, Martinez MC, Martins VR, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG, Meehan KL, Mertens I, Minciacchi VR, Möller A, Møller Jørgensen M, Morales-Kastresana A, Morhayim J, Mullier F, Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Nolte-'t Hoen EN, Noren Hooten N, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz LA, Osteikoetxea X, Østergaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BC, Pink RC, Pisetsky DS, Pogge von Strandmann E, Polakovicova I, Poon IK, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Raposo G, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde E, Rome S, Rouschop KM, Rughetti A, Russell AE, Saá P, Sahoo S, Salas-Huenuleo E, Sánchez C, Saugstad JA, Saul MJ, Schiffelers RM, Schneider R, Schøyen TH, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PR, Silva AM, Skowronek A, Snyder OL, Soares RP, Sódar BW, Soekmadji C, Sotillo J, Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Torrecilhas AC, Tosar JP, Toxavidis V, Urbanelli L, Vader P, van Balkom BW, van der Grein SG, Van Deun J, van Herwijnen MJ, Van Keuren-Jensen K, van Niel G, et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018; 7(1):1535750. PMID: 30637094.
      View in: PubMed
    7. Parchem JG, Kanasaki K, Kanasaki M, Sugimoto H, Xie L, Hamano Y, Lee SB, Gattone VH, Parry S, Strauss JF, Garovic VD, McElrath TF, Lu KH, Sibai BM, LeBleu VS, Carmeliet P, Kalluri R. Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice. J Clin Invest. 2018 Nov 01; 128(11):5008-5017. PMID: 30179860.
      View in: PubMed
    8. Chen Y, LeBleu VS, Carstens JL, Sugimoto H, Zheng X, Malasi S, Saur D, Kalluri R. Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program. EMBO Mol Med. 2018 10; 10(10). PMID: 30120146.
      View in: PubMed
    9. Xu X, Tan X, Tampe B, Wilhelmi T, Hulshoff MS, Saito S, Moser T, Kalluri R, Hasenfuss G, Zeisberg EM, Zeisberg M. High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis. Nat Commun. 2018 08 29; 9(1):3509. PMID: 30158531.
      View in: PubMed
    10. Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Böck BC, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Ghesquière B, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Noel A, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Schulte-Merker S, Smith LEH, Song JW, Stacker SA, Stalin J, Stratman AN, Van de Velde M, van Hinsbergh VWM, Vermeulen PB, Waltenberger J, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW. Consensus guidelines for the use and interpretation of angiogenesis assays. Angiogenesis. 2018 Aug; 21(3):425-532. PMID: 29766399.
      View in: PubMed
    11. Eikesdal HP, Becker LM, Teng Y, Kizu A, Carstens JL, Kanasaki K, Sugimoto H, LeBleu VS, Kalluri R. BMP7 Signaling in TGFBR2-Deficient Stromal Cells Provokes Epithelial Carcinogenesis. Mol Cancer Res. 2018 10; 16(10):1568-1578. PMID: 29934328.
      View in: PubMed
    12. Tampe B, Tampe D, Nyamsuren G, Klöpper F, Rapp G, Kauffels A, Lorf T, Zeisberg EM, Müller GA, Kalluri R, Hakroush S, Zeisberg M. Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure. J Clin Invest. 2018 Jul 02; 128(7):3053-3070. PMID: 29664738.
      View in: PubMed
    13. Mendt M, Kamerkar S, Sugimoto H, McAndrews KM, Wu CC, Gagea M, Yang S, Blanko EVR, Peng Q, Ma X, Marszalek JR, Maitra A, Yee C, Rezvani K, Shpall E, LeBleu VS, Kalluri R. Generation and testing of clinical-grade exosomes for pancreatic cancer. JCI Insight. 2018 Apr 19; 3(8). PMID: 29669940.
      View in: PubMed
    14. LeBleu VS, Kalluri R. A peek into cancer-associated fibroblasts: origins, functions and translational impact. Dis Model Mech. 2018 04 19; 11(4). PMID: 29686035.
      View in: PubMed
    15. Kurywchak P, Tavormina J, Kalluri R. The emerging roles of exosomes in the modulation of immune responses in cancer. Genome Med. 2018 03 26; 10(1):23. PMID: 29580275.
      View in: PubMed
    16. Lovisa S, Kalluri R. Fatty Acid Oxidation Regulates the Activation of Endothelial-to-Mesenchymal Transition. Trends Mol Med. 2018 05; 24(5):432-434. PMID: 29573973.
      View in: PubMed
    17. Gabrusiewicz K, Li X, Wei J, Hashimoto Y, Marisetty AL, Ott M, Wang F, Hawke D, Yu J, Healy LM, Hossain A, Akers JC, Maiti SN, Yamashita S, Shimizu Y, Dunner K, Zal MA, Burks JK, Gumin J, Nwajei F, Rezavanian A, Zhou S, Rao G, Sawaya R, Fuller GN, Huse JT, Antel JP, Li S, Cooper L, Sulman EP, Chen C, Geula C, Kalluri R, Zal T, Heimberger AB. Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes. Oncoimmunology. 2018; 7(4):e1412909. PMID: 29632728.
      View in: PubMed
    18. Brabletz T, Kalluri R, Nieto MA, Weinberg RA. EMT in cancer. Nat Rev Cancer. 2018 02; 18(2):128-134. PMID: 29326430.
      View in: PubMed
    19. Jiao J, González Á, Stevenson HL, Gagea M, Sugimoto H, Kalluri R, Beretta L. Depletion of S100A4+ stromal cells does not prevent HCC development but reduces the stem cell-like phenotype of the tumors. Exp Mol Med. 2018 01 05; 50(1):e422. PMID: 29303514.
      View in: PubMed
    20. Figueroa J, Phillips LM, Shahar T, Hossain A, Gumin J, Kim H, Bean AJ, Calin GA, Fueyo J, Walters ET, Kalluri R, Verhaak RG, Lang FF. Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587. Cancer Res. 2017 11 01; 77(21):5808-5819. PMID: 28855213.
      View in: PubMed
    21. Pickup MW, Owens P, Gorska AE, Chytil A, Ye F, Shi C, Weaver VM, Kalluri R, Moses HL, Novitskiy SV. Development of Aggressive Pancreatic Ductal Adenocarcinomas Depends on Granulocyte Colony Stimulating Factor Secretion in Carcinoma Cells. Cancer Immunol Res. 2017 09; 5(9):718-729. PMID: 28775207.
      View in: PubMed
    22. Kamerkar S, LeBleu VS, Sugimoto H, Yang S, Ruivo CF, Melo SA, Lee JJ, Kalluri R. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. 2017 06 22; 546(7659):498-503. PMID: 28607485.
      View in: PubMed
    23. Kurywchak P, Kalluri R. An evolving function of DNA-containing exosomes in chemotherapy-induced immune response. Cell Res. 2017 Jun; 27(6):722-723. PMID: 28524163.
      View in: PubMed
    24. Carstens JL, Correa de Sampaio P, Yang D, Barua S, Wang H, Rao A, Allison JP, LeBleu VS, Kalluri R. Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer. Nat Commun. 2017 04 27; 8:15095. PMID: 28447602.
      View in: PubMed
    25. Kalluri R, LeBleu VS. Discovery of Double-Stranded Genomic DNA in Circulating Exosomes. Cold Spring Harb Symp Quant Biol. 2016; 81:275-280. PMID: 28424339.
      View in: PubMed
    26. Yang S, Che SP, Kurywchak P, Tavormina JL, Gansmo LB, Correa de Sampaio P, Tachezy M, Bockhorn M, Gebauer F, Haltom AR, Melo SA, LeBleu VS, Kalluri R. Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer. Cancer Biol Ther. 2017 03 04; 18(3):158-165. PMID: 28121262.
      View in: PubMed
    27. Tampe B, Steinle U, Tampe D, Carstens JL, Korsten P, Zeisberg EM, Müller GA, Kalluri R, Zeisberg M. Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression. Kidney Int. 2017 01; 91(1):157-176. PMID: 27692563.
      View in: PubMed
    28. Kalluri R. The biology and function of fibroblasts in cancer. Nat Rev Cancer. 2016 08 23; 16(9):582-98. PMID: 27550820.
      View in: PubMed
    29. Lovisa S, Zeisberg M, Kalluri R. Partial Epithelial-to-Mesenchymal Transition and Other New Mechanisms of Kidney Fibrosis. Trends Endocrinol Metab. 2016 10; 27(10):681-695. PMID: 27372267.
      View in: PubMed
    30. Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2016 05; 22(5):497-505. PMID: 27089513.
      View in: PubMed
    31. Kalluri R. The biology and function of exosomes in cancer. J Clin Invest. 2016 Apr 01; 126(4):1208-15. PMID: 27035812.
      View in: PubMed
    32. Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 2015 Dec 14; 28(6):831-833. PMID: 28843279.
      View in: PubMed
    33. Cleland TP, Schroeter ER, Zamdborg L, Zheng W, Lee JE, Tran JC, Bern M, Duncan MB, Lebleu VS, Ahlf DR, Thomas PM, Kalluri R, Kelleher NL, Schweitzer MH. Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis. J Proteome Res. 2015 Dec 04; 14(12):5252-62. PMID: 26595531.
      View in: PubMed
    34. Zheng X, Carstens JL, Kim J, Scheible M, Kaye J, Sugimoto H, Wu CC, LeBleu VS, Kalluri R. Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature. 2015 Nov 26; 527(7579):525-530. PMID: 26560028.
      View in: PubMed
    35. Lovisa S, LeBleu VS, Tampe B, Sugimoto H, Vadnagara K, Carstens JL, Wu CC, Hagos Y, Burckhardt BC, Pentcheva-Hoang T, Nischal H, Allison JP, Zeisberg M, Kalluri R. Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis. Nat Med. 2015 Sep; 21(9):998-1009. PMID: 26236991.
      View in: PubMed
    36. Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. 2015 Jul 09; 523(7559):177-82. PMID: 26106858.
      View in: PubMed
    37. Léveillé N, Melo CA, Rooijers K, Díaz-Lagares A, Melo SA, Korkmaz G, Lopes R, Moqadam FA, Maia AR, Wijchers PJ, Geeven G, den Boer ML, Kalluri R, de Laat W, Esteller M, Agami R. Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA. Nat Commun. 2015 Mar 27; 6:6520. PMID: 25813522.
      View in: PubMed
    38. Zeisberg M, Kalluri R. Physiology of the Renal Interstitium. Clin J Am Soc Nephrol. 2015 Oct 07; 10(10):1831-40. PMID: 25813241.
      View in: PubMed
    39. Zhang J, Jiao J, Cermelli S, Muir K, Jung KH, Zou R, Rashid A, Gagea M, Zabludoff S, Kalluri R, Beretta L. miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells. Cancer Res. 2015 May 01; 75(9):1859-67. PMID: 25769721.
      View in: PubMed
    40. Keskin D, Kim J, Cooke VG, Wu CC, Sugimoto H, Gu C, De Palma M, Kalluri R, LeBleu VS. Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2. Cell Rep. 2015 Feb 24; 10(7):1066-81. PMID: 25704811.
      View in: PubMed
    41. Xu X, Tan X, Tampe B, Nyamsuren G, Liu X, Maier LS, Sossalla S, Kalluri R, Zeisberg M, Hasenfuss G, Zeisberg EM. Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis. Cardiovasc Res. 2015 Mar 01; 105(3):279-91. PMID: 25616414.
      View in: PubMed
    42. Xu X, Friehs I, Zhong Hu T, Melnychenko I, Tampe B, Alnour F, Iascone M, Kalluri R, Zeisberg M, Del Nido PJ, Zeisberg EM. Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition. Circ Res. 2015 Feb 27; 116(5):857-66. PMID: 25587097.
      View in: PubMed
    43. Tampe B, Tampe D, Zeisberg EM, Müller GA, Bechtel-Walz W, Koziolek M, Kalluri R, Zeisberg M. Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease. EBioMedicine. 2015 Jan; 2(1):19-36. PMID: 25717475.
      View in: PubMed
    44. Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, Qiu L, Vitkin E, Perelman LT, Melo CA, Lucci A, Ivan C, Calin GA, Kalluri R. Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Cancer Cell. 2014 Nov 10; 26(5):707-21. PMID: 25446899.
      View in: PubMed
    45. Miyake T, Kalluri R. Cardiac biology: Cell plasticity helps hearts to repair. Nature. 2014 Oct 30; 514(7524):575-6. PMID: 25317554.
      View in: PubMed
    46. LeBleu VS, O'Connell JT, Gonzalez Herrera KN, Wikman H, Pantel K, Haigis MC, de Carvalho FM, Damascena A, Domingos Chinen LT, Rocha RM, Asara JM, Kalluri R. PGC-1a mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis. Nat Cell Biol. 2014 Oct; 16(10):992-1003, 1-15. PMID: 25241037.
      View in: PubMed
    47. Zeisberg M, Tampe B, LeBleu V, Tampe D, Zeisberg EM, Kalluri R. Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure. Am J Pathol. 2014 Oct; 184(10):2687-98. PMID: 25111226.
      View in: PubMed
    48. Charytan DM, Padera R, Helfand AM, Zeisberg M, Xu X, Liu X, Himmelfarb J, Cinelli A, Kalluri R, Zeisberg EM. Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease. Int J Cardiol. 2014 Sep; 176(1):99-109. PMID: 25049013.
      View in: PubMed
    49. Özdemir BC, Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014 Jun 16; 25(6):719-34. PMID: 24856586.
      View in: PubMed
    50. Ayala de la Peña F, Kanasaki K, Kanasaki M, Vong S, Rovira C, Kalluri R. Specific activation of K-RasG12D allele in the bladder urothelium results in lung alveolar and vascular defects. PLoS One. 2014; 9(4):e95888. PMID: 24760005.
      View in: PubMed
    51. Carstens JL, Lovisa S, Kalluri R. Microenvironment-dependent cues trigger miRNA-regulated feedback loop to facilitate the EMT/MET switch. J Clin Invest. 2014 Apr; 124(4):1458-60. PMID: 24642461.
      View in: PubMed
    52. Tampe B, Tampe D, Müller CA, Sugimoto H, LeBleu V, Xu X, Müller GA, Zeisberg EM, Kalluri R, Zeisberg M. Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis. J Am Soc Nephrol. 2014 May; 25(5):905-12. PMID: 24480825.
      View in: PubMed
    53. Kahlert C, Melo SA, Protopopov A, Tang J, Seth S, Koch M, Zhang J, Weitz J, Chin L, Futreal A, Kalluri R. Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer. J Biol Chem. 2014 Feb 14; 289(7):3869-75. PMID: 24398677.
      View in: PubMed
    54. Atala A. Re: Loss of ß1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype. J Urol. 2013 Dec; 190(6):2305. PMID: 24209569.
      View in: PubMed
    55. Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3. Nat Med. 2013 Jul; 19(7):810-1. PMID: 23836214.
      View in: PubMed
    56. LeBleu VS, Taduri G, O'Connell J, Teng Y, Cooke VG, Woda C, Sugimoto H, Kalluri R. Origin and function of myofibroblasts in kidney fibrosis. Nat Med. 2013 Aug; 19(8):1047-53. PMID: 23817022.
      View in: PubMed
    57. Plaks V, Rinkenberger J, Dai J, Flannery M, Sund M, Kanasaki K, Ni W, Kalluri R, Werb Z. Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):11109-14. PMID: 23776237.
      View in: PubMed
    58. Zeisberg M, Kalluri R. The Kielin/chordin-like protein checkpoint constitutes a system of checks and balances in CKD. J Am Soc Nephrol. 2013 May; 24(6):863-5. PMID: 23687357.
      View in: PubMed
    59. Duncan MB, Yang C, Tanjore H, Boyle PM, Keskin D, Sugimoto H, Zeisberg M, Olsen BR, Kalluri R. Type XVIII collagen is essential for survival during acute liver injury in mice. Dis Model Mech. 2013 Jul; 6(4):942-51. PMID: 23580202.
      View in: PubMed
    60. Kahlert C, Kalluri R. Exosomes in tumor microenvironment influence cancer progression and metastasis. J Mol Med (Berl). 2013 Apr; 91(4):431-7. PMID: 23519402.
      View in: PubMed
    61. Brønnum H, Andersen DC, Schneider M, Sandberg MB, Eskildsen T, Nielsen SB, Kalluri R, Sheikh SP. miR-21 promotes fibrogenic epithelial-to-mesenchymal transition of epicardial mesothelial cells involving Programmed Cell Death 4 and Sprouty-1. PLoS One. 2013; 8(2):e56280. PMID: 23441172.
      View in: PubMed
    62. Kanasaki K, Yu W, von Bodungen M, Larigakis JD, Kanasaki M, Ayala de la Pena F, Kalluri R, Hill WG. Loss of ß1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype. FASEB J. 2013 May; 27(5):1950-61. PMID: 23395910.
      View in: PubMed
    63. Melo SA, Kalluri R. miR-29b moulds the tumour microenvironment to repress metastasis. Nat Cell Biol. 2013 Feb; 15(2):139-40. PMID: 23377028.
      View in: PubMed
    64. LeBleu VS, Teng Y, O'Connell JT, Charytan D, Müller GA, Müller CA, Sugimoto H, Kalluri R. Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis. Nat Med. 2013 Feb; 19(2):227-31. PMID: 23353556.
      View in: PubMed
    65. Borges FT, Melo SA, Özdemir BC, Kato N, Revuelta I, Miller CA, Gattone VH, LeBleu VS, Kalluri R. TGF-ß1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. J Am Soc Nephrol. 2013 Feb; 24(3):385-92. PMID: 23274427.
      View in: PubMed
    66. Melo CA, Drost J, Wijchers PJ, van de Werken H, de Wit E, Oude Vrielink JA, Elkon R, Melo SA, Léveillé N, Kalluri R, de Laat W, Agami R. eRNAs are required for p53-dependent enhancer activity and gene transcription. Mol Cell. 2013 Feb 07; 49(3):524-35. PMID: 23273978.
      View in: PubMed
    67. Zeisberg M, Kalluri R. Cellular mechanisms of tissue fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis. Am J Physiol Cell Physiol. 2013 Feb 01; 304(3):C216-25. PMID: 23255577.
      View in: PubMed
    68. Kieran MW, Kalluri R, Cho YJ. The VEGF pathway in cancer and disease: responses, resistance, and the path forward. Cold Spring Harb Perspect Med. 2012 Dec 01; 2(12):a006593. PMID: 23209176.
      View in: PubMed
    69. Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W. Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26; 2(1):52-61. PMID: 22840396.
      View in: PubMed
    70. Melo SA, Kalluri R. Molecular pathways: microRNAs as cancer therapeutics. Clin Cancer Res. 2012 Aug 15; 18(16):4234-9. PMID: 22711704.
      View in: PubMed
    71. Medici D, Kalluri R. Endothelial-mesenchymal transition and its contribution to the emergence of stem cell phenotype. Semin Cancer Biol. 2012 Oct; 22(5-6):379-84. PMID: 22554794.
      View in: PubMed
    72. Melo SA, Kalluri R. Angiogenesis is controlled by miR-27b associated with endothelial tip cells. Blood. 2012 Mar 15; 119(11):2439-40. PMID: 22422815.
      View in: PubMed
    73. Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe B, Tampe D, Kanasaki K, Zeisberg M, Kalluri R. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nat Med. 2012 Feb 05; 18(3):396-404. PMID: 22306733.
      View in: PubMed
    74. Cooke VG, LeBleu VS, Keskin D, Khan Z, O'Connell JT, Teng Y, Duncan MB, Xie L, Maeda G, Vong S, Sugimoto H, Rocha RM, Damascena A, Brentani RR, Kalluri R. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 2012 Jan 17; 21(1):66-81. PMID: 22264789.
      View in: PubMed
    75. Ho DN, Kohler N, Sigdel A, Kalluri R, Morgan JR, Xu C, Sun S. Penetration of endothelial cell coated multicellular tumor spheroids by iron oxide nanoparticles. Theranostics. 2012; 2(1):66-75. PMID: 22272220.
      View in: PubMed
    76. LeBleu VS, Kalluri R. Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis. Kidney Int. 2011 Dec; 80(11):1119-21. PMID: 22083636.
      View in: PubMed
    77. Vong S, Kalluri R. The role of stromal myofibroblast and extracellular matrix in tumor angiogenesis. Genes Cancer. 2011 Dec; 2(12):1139-45. PMID: 22866205.
      View in: PubMed
    78. De Raedt T, Walton Z, Yecies JL, Li D, Chen Y, Malone CF, Maertens O, Jeong SM, Bronson RT, Lebleu V, Kalluri R, Normant E, Haigis MC, Manning BD, Wong KK, Macleod KF, Cichowski K. Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. Cancer Cell. 2011 Sep 13; 20(3):400-13. PMID: 21907929.
      View in: PubMed
    79. O'Connell JT, Sugimoto H, Cooke VG, MacDonald BA, Mehta AI, LeBleu VS, Dewar R, Rocha RM, Brentani RR, Resnick MB, Neilson EG, Zeisberg M, Kalluri R. VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization. Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38):16002-7. PMID: 21911392.
      View in: PubMed
    80. Charytan DM, Helfand AM, MacDonald BA, Cinelli A, Kalluri R, Zeisberg EM. Circulating endoglin concentration is not elevated in chronic kidney disease. PLoS One. 2011; 6(8):e23718. PMID: 21886815.
      View in: PubMed
    81. Medici D, Potenta S, Kalluri R. Transforming growth factor-ß2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling. Biochem J. 2011 Aug 01; 437(3):515-20. PMID: 21585337.
      View in: PubMed
    82. Tse JC, Kalluri R. Waking up dormant tumors. Breast Cancer Res. 2011 Jun 10; 13(3):310. PMID: 21672272.
      View in: PubMed
    83. San Antonio JD, Schweitzer MH, Jensen ST, Kalluri R, Buckley M, Orgel JP. Dinosaur peptides suggest mechanisms of protein survival. PLoS One. 2011; 6(6):e20381. PMID: 21687667.
      View in: PubMed
    84. Xie L, Duncan MB, Pahler J, Sugimoto H, Martino M, Lively J, Mundel T, Soubasakos M, Rubin K, Takeda T, Inoue M, Lawler J, Hynes RO, Hanahan D, Kalluri R. Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner. Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24):9939-44. PMID: 21622854.
      View in: PubMed
    85. Ayala de la Peña F, Kanasaki K, Kanasaki M, Tangirala N, Maeda G, Kalluri R. Loss of p53 and acquisition of angiogenic microRNA profile are insufficient to facilitate progression of bladder urothelial carcinoma in situ to invasive carcinoma. J Biol Chem. 2011 Jun 10; 286(23):20778-87. PMID: 21388952.
      View in: PubMed
    86. Teng Y, Kanasaki K, Bardeesy N, Sugimoto H, Kalluri R. Deletion of Smad4 in fibroblasts leads to defective chondrocyte maturation and cartilage production in a TGFß type II receptor independent manner. Biochem Biophys Res Commun. 2011 Apr 22; 407(4):633-9. PMID: 21376704.
      View in: PubMed
    87. Melo S, Villanueva A, Moutinho C, Davalos V, Spizzo R, Ivan C, Rossi S, Setien F, Casanovas O, Simo-Riudalbas L, Carmona J, Carrere J, Vidal A, Aytes A, Puertas S, Ropero S, Kalluri R, Croce CM, Calin GA, Esteller M. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc Natl Acad Sci U S A. 2011 Mar 15; 108(11):4394-9. PMID: 21368194.
      View in: PubMed
    88. Bravo-Nuevo A, Sugimoto H, Iyer S, Fallon Z, Lucas JM, Kazerounian S, Prendergast GC, Kalluri R, Shapiro NI, Benjamin LE. RhoB loss prevents streptozotocin-induced diabetes and ameliorates diabetic complications in mice. Am J Pathol. 2011 Jan; 178(1):245-52. PMID: 21224061.
      View in: PubMed
    89. Lee SB, Kalluri R. Mechanistic connection between inflammation and fibrosis. Kidney Int Suppl. 2010 Dec; (119):S22-6. PMID: 21116313.
      View in: PubMed
    90. Zeisberg EM, Kalluri R. Origins of cardiac fibroblasts. Circ Res. 2010 Nov 26; 107(11):1304-12. PMID: 21106947.
      View in: PubMed
    91. Medici D, Shore EM, Lounev VY, Kaplan FS, Kalluri R, Olsen BR. Conversion of vascular endothelial cells into multipotent stem-like cells. Nat Med. 2010 Dec; 16(12):1400-6. PMID: 21102460.
      View in: PubMed
    92. Krenning G, Zeisberg EM, Kalluri R. The origin of fibroblasts and mechanism of cardiac fibrosis. J Cell Physiol. 2010 Nov; 225(3):631-7. PMID: 20635395.
      View in: PubMed
    93. Hertig A, Flier SN, Kalluri R. Contribution of epithelial plasticity to renal transplantation-associated fibrosis. Transplant Proc. 2010 Nov; 42(9 Suppl):S7-12. PMID: 21095454.
      View in: PubMed
    94. LeBleu V, Sund M, Sugimoto H, Birrane G, Kanasaki K, Finan E, Miller CA, Gattone VH, McLaughlin H, Shield CF, Kalluri R. Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly. J Biol Chem. 2010 Dec 31; 285(53):41874-85. PMID: 20847057.
      View in: PubMed
    95. Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, Regnier M, Tang WH, Tian R, Konstam MA, Maron BJ, Seidman CE. Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. Circulation. 2010 Sep 14; 122(11):1130-3. PMID: 20837938.
      View in: PubMed
    96. Wiig H, Keskin D, Kalluri R. Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function. Matrix Biol. 2010 Oct; 29(8):645-56. PMID: 20727409.
      View in: PubMed
    97. Nataraj D, Ernst A, Kalluri R. Idiopathic pulmonary fibrosis is associated with endothelial to mesenchymal transition. Am J Respir Cell Mol Biol. 2010 Aug; 43(2):129-30. PMID: 20651063.
      View in: PubMed
    98. Wiig H, Tenstad O, Iversen PO, Kalluri R, Bjerkvig R. Interstitial fluid: the overlooked component of the tumor microenvironment? Fibrogenesis Tissue Repair. 2010 Jul 23; 3:12. PMID: 20653943.
      View in: PubMed
    99. Keskin D, Kalluri R. NF-kappaB-induced chromatin remodeling regulates angiogenesis. Blood. 2010 Jul 22; 116(3):312-3. PMID: 20651081.
      View in: PubMed
    100. Hamano Y, Okude T, Shirai R, Sato I, Kimura R, Ogawa M, Ueda Y, Yokosuka O, Kalluri R, Ueda S. Lack of collagen XVIII/endostatin exacerbates immune-mediated glomerulonephritis. J Am Soc Nephrol. 2010 Sep; 21(9):1445-55. PMID: 20616167.
      View in: PubMed
    101. Polyak K, Kalluri R. The role of the microenvironment in mammary gland development and cancer. Cold Spring Harb Perspect Biol. 2010 Nov; 2(11):a003244. PMID: 20591988.
      View in: PubMed
    102. Shenoy V, Kanasaki K, Kalluri R. Pre-eclampsia: connecting angiogenic and metabolic pathways. Trends Endocrinol Metab. 2010 Sep; 21(9):529-36. PMID: 20646932.
      View in: PubMed
    103. Bechtel W, McGoohan S, Zeisberg EM, Müller GA, Kalbacher H, Salant DJ, Müller CA, Kalluri R, Zeisberg M. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med. 2010 May; 16(5):544-50. PMID: 20418885.
      View in: PubMed
    104. Flier SN, Tanjore H, Kokkotou EG, Sugimoto H, Zeisberg M, Kalluri R. Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. J Biol Chem. 2010 Jun 25; 285(26):20202-12. PMID: 20363741.
      View in: PubMed
    105. Lee SB, Wong AP, Kanasaki K, Xu Y, Shenoy VK, McElrath TF, Whitesides GM, Kalluri R. Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions. Am J Pathol. 2010 Feb; 176(2):710-20. PMID: 20075204.
      View in: PubMed
    106. LeBleu V, Sugimoto H, Mundel TM, Gerami-Naini B, Finan E, Miller CA, Gattone VH, Lu L, Shield CF, Folkman J, Kalluri R. Stem cell therapies benefit Alport syndrome. J Am Soc Nephrol. 2009 Nov; 20(11):2359-70. PMID: 19833902.
      View in: PubMed
    107. Kizu A, Medici D, Kalluri R. Endothelial-mesenchymal transition as a novel mechanism for generating myofibroblasts during diabetic nephropathy. Am J Pathol. 2009 Oct; 175(4):1371-3. PMID: 19729485.
      View in: PubMed
    108. Ayala F, Dewar R, Kieran M, Kalluri R. Contribution of bone microenvironment to leukemogenesis and leukemia progression. Leukemia. 2009 Dec; 23(12):2233-41. PMID: 19727127.
      View in: PubMed
    109. Kanasaki K, Kalluri R. The biology of preeclampsia. Kidney Int. 2009 Oct; 76(8):831-7. PMID: 19657323.
      View in: PubMed
    110. Duncan MB, Kalluri R. Parstatin, a novel protease-activated receptor 1-derived inhibitor of angiogenesis. Mol Interv. 2009 Aug; 9(4):168-70. PMID: 19720748.
      View in: PubMed
    111. Hertig A, Gangadhar T, Kalluri R. Renal studies provide an insight into cardiac extracellular matrix remodeling during health and disease. J Mol Cell Cardiol. 2010 Mar; 48(3):497-503. PMID: 19646990.
      View in: PubMed
    112. Lee SB, Kanasaki K, Kalluri R. Circulating TGF-beta1 as a reliable biomarker for chronic kidney disease progression in the African-American population. Kidney Int. 2009 Jul; 76(1):10-2. PMID: 19528989.
      View in: PubMed
    113. Eikesdal HP, Kalluri R. Drug resistance associated with antiangiogenesis therapy. Semin Cancer Biol. 2009 Oct; 19(5):310-7. PMID: 19524042.
      View in: PubMed
    114. Kalluri R. EMT: when epithelial cells decide to become mesenchymal-like cells. J Clin Invest. 2009 Jun; 119(6):1417-9. PMID: 19487817.
      View in: PubMed
    115. Sund M, Kalluri R. Tumor stroma derived biomarkers in cancer. Cancer Metastasis Rev. 2009 Jun; 28(1-2):177-83. PMID: 19259624.
      View in: PubMed
    116. Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest. 2009 Jun; 119(6):1420-8. PMID: 19487818.
      View in: PubMed
    117. Sohn RL, Huang P, Kawahara G, Mitchell M, Guyon J, Kalluri R, Kunkel LM, Gussoni E. A role for nephrin, a renal protein, in vertebrate skeletal muscle cell fusion. Proc Natl Acad Sci U S A. 2009 Jun 09; 106(23):9274-9. PMID: 19470472.
      View in: PubMed
    118. Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Res. 2009 May 15; 69(10):4537-44. PMID: 19435903.
      View in: PubMed
    119. Schweitzer MH, Zheng W, Organ CL, Avci R, Suo Z, Freimark LM, Lebleu VS, Duncan MB, Vander Heiden MG, Neveu JM, Lane WS, Cottrell JS, Horner JR, Cantley LC, Kalluri R, Asara JM. Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis. Science. 2009 May 01; 324(5927):626-31. PMID: 19407199.
      View in: PubMed
    120. Zavadil J, Haley J, Kalluri R, Muthuswamy SK, Thompson E. Epithelial-mesenchymal transition. Cancer Res. 2008 Dec 01; 68(23):9574-7. PMID: 19047131.
      View in: PubMed
    121. Zeisberg EM, Potenta SE, Sugimoto H, Zeisberg M, Kalluri R. Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition. J Am Soc Nephrol. 2008 Dec; 19(12):2282-7. PMID: 18987304.
      View in: PubMed
    122. Eikesdal HP, Sugimoto H, Birrane G, Maeshima Y, Cooke VG, Kieran M, Kalluri R. Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity. Proc Natl Acad Sci U S A. 2008 Sep 30; 105(39):15040-5. PMID: 18818312.
      View in: PubMed
    123. Potenta S, Zeisberg E, Kalluri R. The role of endothelial-to-mesenchymal transition in cancer progression. Br J Cancer. 2008 Nov 04; 99(9):1375-9. PMID: 18797460.
      View in: PubMed
    124. Nyberg P, Xie L, Sugimoto H, Colorado P, Sund M, Holthaus K, Sudhakar A, Salo T, Kalluri R. Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor. Exp Cell Res. 2008 Nov 01; 314(18):3292-305. PMID: 18775695.
      View in: PubMed
    125. LeBleu VS, Kalluri R. Stem cell-based therapy for glomerular diseases: an evolving concept. J Am Soc Nephrol. 2008 Sep; 19(9):1621-3. PMID: 18701605.
      View in: PubMed
    126. Kalluri R, Han Y. Targeting TGF-beta and the extracellular matrix in Marfan's syndrome. Dev Cell. 2008 Jul; 15(1):1-2. PMID: 18606132.
      View in: PubMed
    127. Kanasaki K, Palmsten K, Sugimoto H, Ahmad S, Hamano Y, Xie L, Parry S, Augustin HG, Gattone VH, Folkman J, Strauss JF, Kalluri R. Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia. Nature. 2008 Jun 19; 453(7198):1117-21. PMID: 18469803.
      View in: PubMed
    128. Zeisberg M, Kalluri R. Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis. Front Biosci. 2008 May 01; 13:6991-8. PMID: 18508710.
      View in: PubMed
    129. Nyberg P, Salo T, Kalluri R. Tumor microenvironment and angiogenesis. Front Biosci. 2008 May 01; 13:6537-53. PMID: 18508679.
      View in: PubMed
    130. Zeisberg M, Kalluri R. Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease. Pediatr Nephrol. 2008 Sep; 23(9):1395-8. PMID: 18446379.
      View in: PubMed
    131. Mundel TM, Yliniemi AM, Maeshima Y, Sugimoto H, Kieran M, Kalluri R. Type IV collagen alpha6 chain-derived noncollagenous domain 1 (alpha6(IV)NC1) inhibits angiogenesis and tumor growth. Int J Cancer. 2008 Apr 15; 122(8):1738-44. PMID: 18074349.
      View in: PubMed
    132. Kalluri R, Kanasaki K. RNA interference: generic block on angiogenesis. Nature. 2008 Apr 03; 452(7187):543-5. PMID: 18385725.
      View in: PubMed
    133. Xie L, Palmsten K, MacDonald B, Kieran MW, Potenta S, Vong S, Kalluri R. Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth. Exp Biol Med (Maywood). 2008 Feb; 233(2):155-62. PMID: 18222970.
      View in: PubMed
    134. Lebleu VS, Sugimoto H, Miller CA, Gattone VH, Kalluri R. Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease. Lab Invest. 2008 Mar; 88(3):284-92. PMID: 18180701.
      View in: PubMed
    135. Tanjore H, Zeisberg EM, Gerami-Naini B, Kalluri R. Beta1 integrin expression on endothelial cells is required for angiogenesis but not for vasculogenesis. Dev Dyn. 2008 Jan; 237(1):75-82. PMID: 18058911.
      View in: PubMed
    136. Cooke VG, Kalluri R. Chapter 1. Molecular mechanism of type IV collagen-derived endogenous inhibitors of angiogenesis. Methods Enzymol. 2008; 444:1-19. PMID: 19007658.
      View in: PubMed
    137. Wei C, Möller CC, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Bendayan M, Gupta V, Nikolic B, Kalluri R, Carmeliet P, Mundel P, Reiser J. Modification of kidney barrier function by the urokinase receptor. Nat Med. 2008 Jan; 14(1):55-63. PMID: 18084301.
      View in: PubMed
    138. Kanasaki K, Kanda Y, Palmsten K, Tanjore H, Lee SB, Lebleu VS, Gattone VH, Kalluri R. Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Dev Biol. 2008 Jan 15; 313(2):584-93. PMID: 18082680.
      View in: PubMed
    139. Zeisberg EM, Potenta S, Xie L, Zeisberg M, Kalluri R. Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts. Cancer Res. 2007 Nov 01; 67(21):10123-8. PMID: 17974953.
      View in: PubMed
    140. LeBleu VS, Macdonald B, Kalluri R. Structure and function of basement membranes. Exp Biol Med (Maywood). 2007 Oct; 232(9):1121-9. PMID: 17895520.
      View in: PubMed
    141. Zeisberg EM, Tarnavski O, Zeisberg M, Dorfman AL, McMullen JR, Gustafsson E, Chandraker A, Yuan X, Pu WT, Roberts AB, Neilson EG, Sayegh MH, Izumo S, Kalluri R. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med. 2007 Aug; 13(8):952-61. PMID: 17660828.
      View in: PubMed
    142. Tse JC, Kalluri R. Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment. J Cell Biochem. 2007 Jul 01; 101(4):816-29. PMID: 17243120.
      View in: PubMed
    143. Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, Kalluri R. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J Biol Chem. 2007 Aug 10; 282(32):23337-47. PMID: 17562716.
      View in: PubMed
    144. Mundel TM, Kalluri R. Type IV collagen-derived angiogenesis inhibitors. Microvasc Res. 2007 Sep-Nov; 74(2-3):85-9. PMID: 17602710.
      View in: PubMed
    145. Sugimoto H, Grahovac G, Zeisberg M, Kalluri R. Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors. Diabetes. 2007 Jul; 56(7):1825-33. PMID: 17456853.
      View in: PubMed
    146. Cosgrove D, Kalluri R, Miner JH, Segal Y, Borza DB. Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis. Kidney Int. 2007 Apr; 71(7):615-8. PMID: 17290292.
      View in: PubMed
    147. Teng Y, Zeisberg M, Kalluri R. Transcriptional regulation of epithelial-mesenchymal transition. J Clin Invest. 2007 Feb; 117(2):304-6. PMID: 17273552.
      View in: PubMed
    148. Garovic VD, Wagner SJ, Petrovic LM, Gray CE, Hall P, Sugimoto H, Kalluri R, Grande JP. Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia. Nephrol Dial Transplant. 2007 Apr; 22(4):1136-43. PMID: 17255128.
      View in: PubMed
    149. Hahm K, Lukashev ME, Luo Y, Yang WJ, Dolinski BM, Weinreb PH, Simon KJ, Chun Wang L, Leone DR, Lobb RR, McCrann DJ, Allaire NE, Horan GS, Fogo A, Kalluri R, Shield CF, Sheppard D, Gardner HA, Violette SM. Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse. Am J Pathol. 2007 Jan; 170(1):110-25. PMID: 17200187.
      View in: PubMed
    150. Sugimoto H, Mundel TM, Kieran MW, Kalluri R. Identification of fibroblast heterogeneity in the tumor microenvironment. Cancer Biol Ther. 2006 Dec; 5(12):1640-6. PMID: 17106243.
      View in: PubMed
    151. Sugimoto H, Yang C, LeBleu VS, Soubasakos MA, Giraldo M, Zeisberg M, Kalluri R. BMP-7 functions as a novel hormone to facilitate liver regeneration. FASEB J. 2007 Jan; 21(1):256-64. PMID: 17116741.
      View in: PubMed
    152. Dandapani SV, Sugimoto H, Matthews BD, Kolb RJ, Sinha S, Gerszten RE, Zhou J, Ingber DE, Kalluri R, Pollak MR. Alpha-actinin-4 is required for normal podocyte adhesion. J Biol Chem. 2007 Jan 05; 282(1):467-77. PMID: 17082197.
      View in: PubMed
    153. Kalluri R, Zeisberg E. Controlling angiogenesis in heart valves. Nat Med. 2006 Oct; 12(10):1118-9. PMID: 17024200.
      View in: PubMed
    154. Kalluri R. Proteinuria with and without renal glomerular podocyte effacement. J Am Soc Nephrol. 2006 Sep; 17(9):2383-9. PMID: 16914535.
      View in: PubMed
    155. Farazi PA, Zeisberg M, Glickman J, Zhang Y, Kalluri R, DePinho RA. Chronic bile duct injury associated with fibrotic matrix microenvironment provokes cholangiocarcinoma in p53-deficient mice. Cancer Res. 2006 Jul 01; 66(13):6622-7. PMID: 16818635.
      View in: PubMed
    156. Kalluri R, Zeisberg M. Fibroblasts in cancer. Nat Rev Cancer. 2006 May; 6(5):392-401. PMID: 16572188.
      View in: PubMed
    157. Sugimoto H, Mundel TM, Sund M, Xie L, Cosgrove D, Kalluri R. Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease. Proc Natl Acad Sci U S A. 2006 May 09; 103(19):7321-6. PMID: 16648256.
      View in: PubMed
    158. Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol. 2006 Mar 27; 172(7):973-81. PMID: 16567498.
      View in: PubMed
    159. Zeisberg M, Khurana M, Rao VH, Cosgrove D, Rougier JP, Werner MC, Shield CF, Werb Z, Kalluri R. Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease. PLoS Med. 2006 Apr; 3(4):e100. PMID: 16509766.
      View in: PubMed
    160. Tanjore H, Kalluri R. The role of type IV collagen and basement membranes in cancer progression and metastasis. Am J Pathol. 2006 Mar; 168(3):715-7. PMID: 16507886.
      View in: PubMed
    161. Zeisberg M, Kramer K, Sindhi N, Sarkar P, Upton M, Kalluri R. De-differentiation of primary human hepatocytes depends on the composition of specialized liver basement membrane. Mol Cell Biochem. 2006 Feb; 283(1-2):181-9. PMID: 16444601.
      View in: PubMed
    162. Wang B, Sun J, Kitamoto S, Yang M, Grubb A, Chapman HA, Kalluri R, Shi GP. Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. J Biol Chem. 2006 Mar 03; 281(9):6020-9. PMID: 16365041.
      View in: PubMed
    163. Sund M, Zeisberg M, Kalluri R. Endogenous stimulators and inhibitors of angiogenesis in gastrointestinal cancers: basic science to clinical application. Gastroenterology. 2005 Dec; 129(6):2076-91. PMID: 16344073.
      View in: PubMed
    164. Zehnder AF, Adams JC, Santi PA, Kristiansen AG, Wacharasindhu C, Mann S, Kalluri R, Gregory MC, Kashtan CE, Merchant SN. Distribution of type IV collagen in the cochlea in Alport syndrome. Arch Otolaryngol Head Neck Surg. 2005 Nov; 131(11):1007-13. PMID: 16301374.
      View in: PubMed
    165. MacDonald BA, Sund M, Grant MA, Pfaff KL, Holthaus K, Zon LI, Kalluri R. Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome. Blood. 2006 Mar 01; 107(5):1908-15. PMID: 16254142.
      View in: PubMed
    166. Sudhakar A, Nyberg P, Keshamouni VG, Mannam AP, Li J, Sugimoto H, Cosgrove D, Kalluri R. Human alpha1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by alpha1beta1 integrin. J Clin Invest. 2005 Oct; 115(10):2801-10. PMID: 16151532.
      View in: PubMed
    167. Okada H, Kalluri R. Cellular and molecular pathways that lead to progression and regression of renal fibrogenesis. Curr Mol Med. 2005 Aug; 5(5):467-74. PMID: 16101477.
      View in: PubMed
    168. Hamano Y, Kalluri R. Tumstatin, the NC1 domain of alpha3 chain of type IV collagen, is an endogenous inhibitor of pathological angiogenesis and suppresses tumor growth. Biochem Biophys Res Commun. 2005 Jul 29; 333(2):292-8. PMID: 15979458.
      View in: PubMed
    169. Okada H, Kalluri R. Recapitulation of kidney development paradigms by BMP-7 reverses chronic renal injury. Clin Exp Nephrol. 2005 Jun; 9(2):100-1. PMID: 15980942.
      View in: PubMed
    170. Reiser J, Polu KR, Möller CC, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR. TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet. 2005 Jul; 37(7):739-44. PMID: 15924139.
      View in: PubMed
    171. Nyberg P, Xie L, Kalluri R. Endogenous inhibitors of angiogenesis. Cancer Res. 2005 May 15; 65(10):3967-79. PMID: 15899784.
      View in: PubMed
    172. Sund M, Maeshima Y, Kalluri R. Bifunctional promoter of type IV collagen COL4A5 and COL4A6 genes regulates the expression of alpha5 and alpha6 chains in a distinct cell-specific fashion. Biochem J. 2005 May 01; 387(Pt 3):755-61. PMID: 15598179.
      View in: PubMed
    173. Reynolds J, Prodromidi EI, Juggapah JK, Abbott DS, Holthaus KA, Kalluri R, Pusey CD. Nasal administration of recombinant rat alpha3(IV)NC1 prevents the development of experimental autoimmune glomerulonephritis in the WKY rat. J Am Soc Nephrol. 2005 May; 16(5):1350-9. PMID: 15814836.
      View in: PubMed
    174. Charytan D, MacDonald B, Sugimoto H, Pastan S, Staton G, Hennigar R, Kalluri R. An unusual case of pulmonary-renal syndrome associated with defects in type IV collagen composition and anti-glomerular basement membrane autoantibodies. Am J Kidney Dis. 2005 Apr; 45(4):743-8. PMID: 15806477.
      View in: PubMed
    175. Sund M, Hamano Y, Sugimoto H, Sudhakar A, Soubasakos M, Yerramalla U, Benjamin LE, Lawler J, Kieran M, Shah A, Kalluri R. Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):2934-9. PMID: 15710885.
      View in: PubMed
    176. Krishna TH, Mahipal S, Sudhakar A, Sugimoto H, Kalluri R, Rao KS. Reduced DNA gap repair in aging rat neuronal extracts and its restoration by DNA polymerase beta and DNA-ligase. J Neurochem. 2005 Feb; 92(4):818-23. PMID: 15686483.
      View in: PubMed
    177. Zeisberg M, Soubasakos MA, Kalluri R. Animal models of renal fibrosis. Methods Mol Med. 2005; 117:261-72. PMID: 16118458.
      View in: PubMed
    178. Grant MA, Kalluri R. Structural basis for the functions of endogenous angiogenesis inhibitors. Cold Spring Harb Symp Quant Biol. 2005; 70:399-410. PMID: 16869777.
      View in: PubMed
    179. Zeisberg M, Shah AA, Kalluri R. Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J Biol Chem. 2005 Mar 04; 280(9):8094-100. PMID: 15591043.
      View in: PubMed
    180. Zeisberg M, Kalluri R. Experimental strategies to reverse chronic renal disease. Blood Purif. 2004; 22(5):440-5. PMID: 15359103.
      View in: PubMed
    181. Sund M, Xie L, Kalluri R. The contribution of vascular basement membranes and extracellular matrix to the mechanics of tumor angiogenesis. APMIS. 2004 Jul-Aug; 112(7-8):450-62. PMID: 15563309.
      View in: PubMed
    182. Benigni A, Gagliardini E, Tomasoni S, Abbate M, Ruggenenti P, Kalluri R, Remuzzi G. Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy. Kidney Int. 2004 Jun; 65(6):2193-200. PMID: 15149332.
      View in: PubMed
    183. Charytan D, Torre A, Khurana M, Nicastri A, Stillman IE, Kalluri R. Allograft rejection and glomerular basement membrane antibodies in Alport's syndrome. J Nephrol. 2004 May-Jun; 17(3):431-5. PMID: 15365966.
      View in: PubMed
    184. Reiser J, von Gersdorff G, Loos M, Oh J, Asanuma K, Giardino L, Rastaldi MP, Calvaresi N, Watanabe H, Schwarz K, Faul C, Kretzler M, Davidson A, Sugimoto H, Kalluri R, Sharpe AH, Kreidberg JA, Mundel P. Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest. 2004 May; 113(10):1390-7. PMID: 15146236.
      View in: PubMed
    185. Zeisberg M, Müller GA, Kalluri R. Are there endogenous molecules that protect kidneys from injury? The case for bone morphogenic protein-7 (BMP-7). Nephrol Dial Transplant. 2004 Apr; 19(4):759-61. PMID: 15031324.
      View in: PubMed
    186. Hamano Y, Sugimoto H, Soubasakos MA, Kieran M, Olsen BR, Lawler J, Sudhakar A, Kalluri R. Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Res. 2004 Mar 01; 64(5):1570-4. PMID: 14996710.
      View in: PubMed
    187. Folkman J, Kalluri R. Cancer without disease. Nature. 2004 Feb 26; 427(6977):787. PMID: 14985739.
      View in: PubMed
    188. Zeisberg M, Kalluri R. The role of epithelial-to-mesenchymal transition in renal fibrosis. J Mol Med (Berl). 2004 Mar; 82(3):175-81. PMID: 14752606.
      View in: PubMed
    189. Bhattacharya G, Kalluri R, Orten DJ, Kimberling WJ, Cosgrove D. A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure. J Cell Sci. 2004 Jan 15; 117(Pt 2):233-42. PMID: 14676276.
      View in: PubMed
    190. Yang C, Zeisberg M, Lively JC, Nyberg P, Afdhal N, Kalluri R. Integrin alpha1beta1 and alpha2beta1 are the key regulators of hepatocarcinoma cell invasion across the fibrotic matrix microenvironment. Cancer Res. 2003 Dec 01; 63(23):8312-7. PMID: 14678990.
      View in: PubMed
    191. Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest. 2003 Dec; 112(12):1776-84. PMID: 14679171.
      View in: PubMed
    192. Salama AD, Chaudhry AN, Holthaus KA, Mosley K, Kalluri R, Sayegh MH, Lechler RI, Pusey CD, Lightstone L. Regulation by CD25+ lymphocytes of autoantigen-specific T-cell responses in Goodpasture's (anti-GBM) disease. Kidney Int. 2003 Nov; 64(5):1685-94. PMID: 14531801.
      View in: PubMed
    193. Charytan DM, Le DD, Grossman JM, Holthaus KA, Kalluri R. Antiglomerular basement membrane autoantibodies are nonpathogenic in Wegener's granulomatosis. Am J Med. 2003 Oct 01; 115(5):414-5. PMID: 14553885.
      View in: PubMed
    194. Zeisberg M, Bottiglio C, Kumar N, Maeshima Y, Strutz F, Müller GA, Kalluri R. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. Am J Physiol Renal Physiol. 2003 Dec; 285(6):F1060-7. PMID: 12915382.
      View in: PubMed
    195. Gagliardini E, Benigni A, Tomasoni S, Abbate M, Kalluri R, Remuzzi G. Targeted downregulation of extracellular nephrin in human IgA nephropathy. Am J Nephrol. 2003 Jul-Aug; 23(4):277-86. PMID: 12853730.
      View in: PubMed
    196. McDonald GA, Sarkar P, Rennke H, Unemori E, Kalluri R, Sukhatme VP. Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo. Am J Physiol Renal Physiol. 2003 Jul; 285(1):F59-67. PMID: 12820641.
      View in: PubMed
    197. Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med. 2003 Jul; 9(7):964-8. PMID: 12808448.
      View in: PubMed
    198. Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer. 2003 Jun; 3(6):422-33. PMID: 12778132.
      View in: PubMed
    199. Kos CH, Le TC, Sinha S, Henderson JM, Kim SH, Sugimoto H, Kalluri R, Gerszten RE, Pollak MR. Mice deficient in alpha-actinin-4 have severe glomerular disease. J Clin Invest. 2003 Jun; 111(11):1683-90. PMID: 12782671.
      View in: PubMed
    200. Hamano Y, Zeisberg M, Sugimoto H, Lively JC, Maeshima Y, Yang C, Hynes RO, Werb Z, Sudhakar A, Kalluri R. Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. Cancer Cell. 2003 Jun; 3(6):589-601. PMID: 12842087.
      View in: PubMed
    201. Hopfer H, Maron R, Butzmann U, Helmchen U, Weiner HL, Kalluri R. The importance of cell-mediated immunity in the course and severity of autoimmune anti-glomerular basement membrane disease in mice. FASEB J. 2003 May; 17(8):860-8. PMID: 12724345.
      View in: PubMed
    202. Sudhakar A, Sugimoto H, Yang C, Lively J, Zeisberg M, Kalluri R. Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4766-71. PMID: 12682293.
      View in: PubMed
    203. Sugimoto H, Hamano Y, Charytan D, Cosgrove D, Kieran M, Sudhakar A, Kalluri R. Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria. J Biol Chem. 2003 Apr 11; 278(15):12605-8. PMID: 12538598.
      View in: PubMed
    204. Yang C, Zeisberg M, Mosterman B, Sudhakar A, Yerramalla U, Holthaus K, Xu L, Eng F, Afdhal N, Kalluri R. Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors. Gastroenterology. 2003 Jan; 124(1):147-59. PMID: 12512039.
      View in: PubMed
    205. Kalluri R, Zeisberg M. Exploring the connection between chronic renal fibrosis and bone morphogenic protein-7. Histol Histopathol. 2003 01; 18(1):217-24. PMID: 12507301.
      View in: PubMed
    206. Tsukaguchi H, Sudhakar A, Le TC, Nguyen T, Yao J, Schwimmer JA, Schachter AD, Poch E, Abreu PF, Appel GB, Pereira AB, Kalluri R, Pollak MR. NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated allele. J Clin Invest. 2002 Dec; 110(11):1659-66. PMID: 12464671.
      View in: PubMed
    207. Iglesias-de la Cruz MC, Ziyadeh FN, Isono M, Kouahou M, Han DC, Kalluri R, Mundel P, Chen S. Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes. Kidney Int. 2002 Sep; 62(3):901-13. PMID: 12164872.
      View in: PubMed
    208. Natoli TA, Liu J, Eremina V, Hodgens K, Li C, Hamano Y, Mundel P, Kalluri R, Miner JH, Quaggin SE, Kreidberg JA. A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development. J Am Soc Nephrol. 2002 Aug; 13(8):2058-67. PMID: 12138137.
      View in: PubMed
    209. Bloom RD, O'Connor T, Cizman B, Kalluri R, Naji A, Madaio MP. Intrathymic kidney cells delay the onset of lupus nephritis in MRL-lpr/lpr mice. Int Immunol. 2002 Aug; 14(8):867-71. PMID: 12147623.
      View in: PubMed
    210. Zeisberg M, Ericksen MB, Hamano Y, Neilson EG, Ziyadeh F, Kalluri R. Differential expression of type IV collagen isoforms in rat glomerular endothelial and mesangial cells. Biochem Biophys Res Commun. 2002 Jul 12; 295(2):401-7. PMID: 12150963.
      View in: PubMed
    211. Zeisberg M, Maeshima Y, Mosterman B, Kalluri R. Renal fibrosis. Extracellular matrix microenvironment regulates migratory behavior of activated tubular epithelial cells. Am J Pathol. 2002 Jun; 160(6):2001-8. PMID: 12057905.
      View in: PubMed
    212. Hamano Y, Grunkemeyer JA, Sudhakar A, Zeisberg M, Cosgrove D, Morello R, Lee B, Sugimoto H, Kalluri R. Determinants of vascular permeability in the kidney glomerulus. J Biol Chem. 2002 Aug 23; 277(34):31154-62. PMID: 12039968.
      View in: PubMed
    213. Strutz F, Zeisberg M, Ziyadeh FN, Yang CQ, Kalluri R, Müller GA, Neilson EG. Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney Int. 2002 May; 61(5):1714-28. PMID: 11967021.
      View in: PubMed
    214. Meyers KE, Allen J, Gehret J, Jacobovits A, Gallo M, Neilson EG, Hopfer H, Kalluri R, Madaio MP. Human antiglomerular basement membrane autoantibody disease in XenoMouse II. Kidney Int. 2002 May; 61(5):1666-73. PMID: 11967016.
      View in: PubMed
    215. Reimer CL, Agata N, Tammam JG, Bamberg M, Dickerson WM, Kamphaus GD, Rook SL, Milhollen M, Fram R, Kalluri R, Kufe D, Kharbanda S. Antineoplastic effects of chemotherapeutic agents are potentiated by NM-3, an inhibitor of angiogenesis. Cancer Res. 2002 Feb 01; 62(3):789-95. PMID: 11830534.
      View in: PubMed
    216. Maeshima Y, Sudhakar A, Lively JC, Ueki K, Kharbanda S, Kahn CR, Sonenberg N, Hynes RO, Kalluri R. Tumstatin, an endothelial cell-specific inhibitor of protein synthesis. Science. 2002 Jan 04; 295(5552):140-3. PMID: 11778052.
      View in: PubMed
    217. Kalluri R. Discovery of type IV collagen non-collagenous domains as novel integrin ligands and endogenous inhibitors of angiogenesis. Cold Spring Harb Symp Quant Biol. 2002; 67:255-66. PMID: 12858548.
      View in: PubMed
    218. Zeisberg M, Bonner G, Maeshima Y, Colorado P, Müller GA, Strutz F, Kalluri R. Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation. Am J Pathol. 2001 Oct; 159(4):1313-21. PMID: 11583959.
      View in: PubMed
    219. Okada H, Inoue T, Kanno Y, Kobayashi T, Ban S, Kalluri R, Suzuki H. Renal fibroblast-like cells in Goodpasture syndrome rats. Kidney Int. 2001 Aug; 60(2):597-606. PMID: 11473642.
      View in: PubMed
    220. Maeshima Y, Yerramalla UL, Dhanabal M, Holthaus KA, Barbashov S, Kharbanda S, Reimer C, Manfredi M, Dickerson WM, Kalluri R. Extracellular matrix-derived peptide binds to alpha(v)beta(3) integrin and inhibits angiogenesis. J Biol Chem. 2001 Aug 24; 276(34):31959-68. PMID: 11399763.
      View in: PubMed
    221. Benigni A, Tomasoni S, Gagliardini E, Zoja C, Grunkemeyer JA, Kalluri R, Remuzzi G. Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis. J Am Soc Nephrol. 2001 May; 12(5):941-8. PMID: 11316852.
      View in: PubMed
    222. Karumanchi SA, Jha V, Ramchandran R, Karihaloo A, Tsiokas L, Chan B, Dhanabal M, Hanai JI, Venkataraman G, Shriver Z, Keiser N, Kalluri R, Zeng H, Mukhopadhyay D, Chen RL, Lander AD, Hagihara K, Yamaguchi Y, Sasisekharan R, Cantley L, Sukhatme VP. Cell surface glypicans are low-affinity endostatin receptors. Mol Cell. 2001 Apr; 7(4):811-22. PMID: 11336704.
      View in: PubMed
    223. Maeshima Y, Manfredi M, Reimer C, Holthaus KA, Hopfer H, Chandamuri BR, Kharbanda S, Kalluri R. Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin. J Biol Chem. 2001 May 04; 276(18):15240-8. PMID: 11278365.
      View in: PubMed
    224. Chugh S, Yuan H, Topham PS, Haydar SA, Mittal V, Taylor GA, Kalluri R, Salant DJ. Aminopeptidase A: a nephritogenic target antigen of nephrotoxic serum. Kidney Int. 2001 Feb; 59(2):601-13. PMID: 11168941.
      View in: PubMed
    225. Salloum RM, Jaskowiak NT, Mauceri HJ, Seetharam S, Beckett MA, Koons AM, Hari DM, Gupta VK, Reimer C, Kalluri R, Posner MC, Hellman S, Kufe DW, Weichselbaum RR. NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity. Cancer Res. 2000 Dec 15; 60(24):6958-63. PMID: 11156396.
      View in: PubMed
    226. Cosgrove D, Rodgers K, Meehan D, Miller C, Bovard K, Gilroy A, Gardner H, Kotelianski V, Gotwals P, Amatucci A, Kalluri R. Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy. Am J Pathol. 2000 Nov; 157(5):1649-59. PMID: 11073824.
      View in: PubMed
    227. Hanna NN, Seetharam S, Mauceri HJ, Beckett MA, Jaskowiak NT, Salloum RM, Hari D, Dhanabal M, Ramchandran R, Kalluri R, Sukhatme VP, Kufe DW, Weichselbaum RR. Antitumor interaction of short-course endostatin and ionizing radiation. Cancer J. 2000 Sep-Oct; 6(5):287-93. PMID: 11079167.
      View in: PubMed
    228. Maeshima Y, Colorado PC, Kalluri R. Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties. J Biol Chem. 2000 Aug 04; 275(31):23745-50. PMID: 10837460.
      View in: PubMed
    229. Maeshima Y, Colorado PC, Torre A, Holthaus KA, Grunkemeyer JA, Ericksen MB, Hopfer H, Xiao Y, Stillman IE, Kalluri R. Distinct antitumor properties of a type IV collagen domain derived from basement membrane. J Biol Chem. 2000 Jul 14; 275(28):21340-8. PMID: 10766752.
      View in: PubMed
    230. Rutgers A, Meyers KE, Canziani G, Kalluri R, Lin J, Madaio MP. High affinity of anti-GBM antibodies from Goodpasture and transplanted Alport patients to alpha3(IV)NC1 collagen. Kidney Int. 2000 Jul; 58(1):115-22. PMID: 10886555.
      View in: PubMed
    231. Kalluri R, Sukhatme VP. Fibrosis and angiogenesis. Curr Opin Nephrol Hypertens. 2000 Jul; 9(4):413-8. PMID: 10926178.
      View in: PubMed
    232. Kalluri R, Cantley LG, Kerjaschki D, Neilson EG. Reactive oxygen species expose cryptic epitopes associated with autoimmune goodpasture syndrome. J Biol Chem. 2000 Jun 30; 275(26):20027-32. PMID: 10748075.
      View in: PubMed
    233. Colorado PC, Torre A, Kamphaus G, Maeshima Y, Hopfer H, Takahashi K, Volk R, Zamborsky ED, Herman S, Sarkar PK, Ericksen MB, Dhanabal M, Simons M, Post M, Kufe DW, Weichselbaum RR, Sukhatme VP, Kalluri R. Anti-angiogenic cues from vascular basement membrane collagen. Cancer Res. 2000 May 01; 60(9):2520-6. PMID: 10811134.
      View in: PubMed
    234. Kalluri R, Cosgrove D. Assembly of type IV collagen. Insights from alpha3(IV) collagen-deficient mice. J Biol Chem. 2000 Apr 28; 275(17):12719-24. PMID: 10777566.
      View in: PubMed
    235. Okada H, Moriwaki K, Kalluri R, Imai H, Ban S, Takahama M, Suzuki H. Inhibition of monocyte chemoattractant protein-1 expression in tubular epithelium attenuates tubulointerstitial alteration in rat Goodpasture syndrome. Kidney Int. 2000 Mar; 57(3):927-36. PMID: 10720946.
      View in: PubMed
    236. Kalluri R, Torre A, Shield CF, Zamborsky ED, Werner MC, Suchin E, Wolf G, Helmchen UM, van den Heuvel LP, Grossman R, Aradhye S, Neilson EG. Identification of alpha3, alpha4, and alpha5 chains of type IV collagen as alloantigens for Alport posttransplant anti-glomerular basement membrane antibodies. Transplantation. 2000 Feb 27; 69(4):679-83. PMID: 10708133.
      View in: PubMed
    237. Kamphaus GD, Colorado PC, Panka DJ, Hopfer H, Ramchandran R, Torre A, Maeshima Y, Mier JW, Sukhatme VP, Kalluri R. Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth. J Biol Chem. 2000 Jan 14; 275(2):1209-15. PMID: 10625665.
      View in: PubMed
    238. Okada H, Moriwaki K, Kalluri R, Takenaka T, Imai H, Ban S, Takahama M, Suzuki H. Osteopontin expressed by renal tubular epithelium mediates interstitial monocyte infiltration in rats. Am J Physiol Renal Physiol. 2000 Jan; 278(1):F110-21. PMID: 10644662.
      View in: PubMed
    239. Sayers R, Kalluri R, Rodgers KD, Shield CF, Meehan DT, Cosgrove D. Role for transforming growth factor-beta1 in alport renal disease progression. Kidney Int. 1999 Nov; 56(5):1662-73. PMID: 10571774.
      View in: PubMed
    240. Van Vliet AI, Van Alderwegen IE, Baelde HJ, de Heer E, Killen PD, Kalluri RK, Bruijn JA, Bergijk EC. Differential expression of collagen type IV alpha-chains in the tubulointerstitial compartment in experimental chronic serum sickness nephritis. J Pathol. 1999 Oct; 189(2):279-87. PMID: 10547587.
      View in: PubMed
    241. Wolf G, Kalluri R, Ziyadeh FN, Neilson EG, Stahl RA. Angiotensin II induces alpha3(IV) collagen expression in cultured murine proximal tubular cells. Proc Assoc Am Physicians. 1999 Jul-Aug; 111(4):357-64. PMID: 10417744.
      View in: PubMed
    242. Kalluri R. Goodpasture syndrome. Kidney Int. 1999 Mar; 55(3):1120-2. PMID: 10027952.
      View in: PubMed
    243. Lei H, Kalluri R, Furth EE, Baker AH, Strauss JF. Rat amnion type IV collagen composition and metabolism: implications for membrane breakdown. Biol Reprod. 1999 Jan; 60(1):176-82. PMID: 9858503.
      View in: PubMed
    244. Lei H, Furth EE, Kalluri R, Wakenell P, Kallen CB, Jeffrey JJ, Leboy PS, Strauss JF. Induction of matrix metalloproteinases and collagenolysis in chick embryonic membranes before hatching. Biol Reprod. 1999 Jan; 60(1):183-9. PMID: 9858504.
      View in: PubMed
    245. Abbate M, Kalluri R, Corna D, Yamaguchi N, McCluskey RT, Hudson BG, Andres G, Zoja C, Remuzzi G. Experimental Goodpasture's syndrome in Wistar-Kyoto rats immunized with alpha3 chain of type IV collagen. Kidney Int. 1998 Nov; 54(5):1550-61. PMID: 9844131.
      View in: PubMed
    246. Minto AW, Kalluri R, Togawa M, Bergijk EC, Killen PD, Salant DJ. Augmented expression of glomerular basement membrane specific type IV collagen isoforms (alpha3-alpha5) in experimental membranous nephropathy. Proc Assoc Am Physicians. 1998 May-Jun; 110(3):207-17. PMID: 9625527.
      View in: PubMed
    247. Bergijk EC, Van Alderwegen IE, Baelde HJ, de Heer E, Funabiki K, Miyai H, Killen PD, Kalluri RK, Bruijn JA. Differential expression of collagen IV isoforms in experimental glomerulosclerosis. J Pathol. 1998 Mar; 184(3):307-15. PMID: 9614384.
      View in: PubMed
    248. Meyers KE, Kinniry PA, Kalluri R, Neilson EG, Madaio MP. Human Goodpasture anti-alpha3(IV)NC1 autoantibodies share structural determinants. Kidney Int. 1998 Feb; 53(2):402-7. PMID: 9461099.
      View in: PubMed
    249. Kalluri R, Gattone VH, Hudson BG. Identification and localization of type IV collagen chains in the inner ear cochlea. Connect Tissue Res. 1998; 37(1-2):143-50. PMID: 9643653.
      View in: PubMed
    250. Kalluri R, Danoff TM, Okada H, Neilson EG. Susceptibility to anti-glomerular basement membrane disease and Goodpasture syndrome is linked to MHC class II genes and the emergence of T cell-mediated immunity in mice. J Clin Invest. 1997 Nov 01; 100(9):2263-75. PMID: 9410904.
      View in: PubMed
    251. Kalluri R, Meyers K, Mogyorosi A, Madaio MP, Neilson EG. Goodpasture syndrome involving overlap with Wegener's granulomatosis and anti-glomerular basement membrane disease. J Am Soc Nephrol. 1997 Nov; 8(11):1795-800. PMID: 9355084.
      View in: PubMed
    252. Okada H, Danoff TM, Kalluri R, Neilson EG. Early role of Fsp1 in epithelial-mesenchymal transformation. Am J Physiol. 1997 10; 273(4):F563-74. PMID: 9362334.
      View in: PubMed
    253. Tuori AJ, Virtanen I, Aine E, Kalluri R, Miner JH, Uusitalo HM. The immunohistochemical composition of corneal basement membrane in keratoconus. Curr Eye Res. 1997 Aug; 16(8):792-801. PMID: 9255508.
      View in: PubMed
    254. Kahsai TZ, Enders GC, Gunwar S, Brunmark C, Wieslander J, Kalluri R, Zhou J, Noelken ME, Hudson BG. Seminiferous tubule basement membrane. Composition and organization of type IV collagen chains, and the linkage of alpha3(IV) and alpha5(IV) chains. J Biol Chem. 1997 Jul 04; 272(27):17023-32. PMID: 9202017.
      View in: PubMed
    255. Lohi J, Korhonen M, Leivo I, Kangas L, Tani T, Kalluri R, Miner JH, Lehto VP, Virtanen I. Expression of type IV collagen alpha1(IV)-alpha6(IV) polypeptides in normal and developing human kidney and in renal cell carcinomas and oncocytomas. Int J Cancer. 1997 Jul 03; 72(1):43-9. PMID: 9212221.
      View in: PubMed
    256. Kalluri R, Shield CF, Todd P, Hudson BG, Neilson EG. Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis. J Clin Invest. 1997 May 15; 99(10):2470-8. PMID: 9153291.
      View in: PubMed
    257. Vargas MT, Gustilo K, D'Andrea DM, Kalluri R, Foster MH, Madaio MP. Structural features of nephritogenic lupus autoantibodies. Methods. 1997 Jan; 11(1):62-9. PMID: 8990090.
      View in: PubMed
    258. Ziyadeh FN, Mogyorósi A, Kalluri R. Early and advanced non-enzymatic glycation products in the pathogenesis of diabetic kidney disease. Exp Nephrol. 1997 Jan-Feb; 5(1):2-9. PMID: 9052842.
      View in: PubMed
    259. Ortiz-Arduan A, Danoff TM, Kalluri R, González-Cuadrado S, Karp SL, Elkon K, Egido J, Neilson EG. Regulation of Fas and Fas ligand expression in cultured murine renal cells and in the kidney during endotoxemia. Am J Physiol. 1996 Dec; 271(6 Pt 2):F1193-201. PMID: 8997393.
      View in: PubMed
    260. Lei H, Furth EE, Kalluri R, Chiou T, Tilly KI, Tilly JL, Elkon KB, Jeffrey JJ, Strauss JF. A program of cell death and extracellular matrix degradation is activated in the amnion before the onset of labor. J Clin Invest. 1996 Nov 01; 98(9):1971-8. PMID: 8903315.
      View in: PubMed
    261. Boutaud AA, Kalluri R, Kahsai TZ, Noelken ME, Hudson BG. Goodpasture syndrome: selective removal of anti-alpha 3 (IV) collagen autoantibodies. A potential therapeutic alternative to plasmapheresis. Exp Nephrol. 1996 Jul-Aug; 4(4):205-12. PMID: 8864724.
      View in: PubMed
    262. Thorner PS, Zheng K, Kalluri R, Jacobs R, Hudson BG. Coordinate gene expression of the alpha3, alpha4, and alpha5 chains of collagen type IV. Evidence from a canine model of X-linked nephritis with a COL4A5 gene mutation. J Biol Chem. 1996 Jun 07; 271(23):13821-8. PMID: 8662866.
      View in: PubMed
    263. Kalluri R, Sun MJ, Hudson BG, Neilson EG. The Goodpasture autoantigen. Structural delineation of two immunologically privileged epitopes on alpha3(IV) chain of type IV collagen. J Biol Chem. 1996 Apr 12; 271(15):9062-8. PMID: 8621555.
      View in: PubMed
    264. Kalluri R, Petrides S, Wilson CB, Tomaszewski JE, Palevsky HI, Grippi MA, Madaio MP, Neilson EG. Anti-alpha1(IV) collagen autoantibodies associated with lung adenocarcinoma presenting as the Goodpasture syndrome. Ann Intern Med. 1996 Apr 01; 124(7):651-3. PMID: 8607593.
      View in: PubMed
    265. Merkel F, Kalluri R, Marx M, Enders U, Stevanovic S, Giegerich G, Neilson EG, Rammensee HG, Hudson BG, Weber M. Autoreactive T-cells in Goodpasture's syndrome recognize the N-terminal NC1 domain on alpha 3 type IV collagen. Kidney Int. 1996 Apr; 49(4):1127-33. PMID: 8691734.
      View in: PubMed
    266. Kalluri R, Melendez E, Rumpf KW, Sattler K, Müller GA, Strutz F, Neilson EG. Specificity of circulating and tissue-bound autoantibodies in Goodpasture syndrome. Proc Assoc Am Physicians. 1996 Mar; 108(2):134-9. PMID: 8705733.
      View in: PubMed
    267. Okada H, Strutz F, Danoff TM, Kalluri R, Neilson EG. Possible mechanisms of renal fibrosis. Contrib Nephrol. 1996; 118:147-54. PMID: 8744052.
      View in: PubMed
    268. Peissel B, Geng L, Kalluri R, Kashtan C, Rennke HG, Gallo GR, Yoshioka K, Sun MJ, Hudson BG, Neilson EG, et al. Comparative distribution of the alpha 1(IV), alpha 5(IV), and alpha 6(IV) collagen chains in normal human adult and fetal tissues and in kidneys from X-linked Alport syndrome patients. J Clin Invest. 1995 Oct; 96(4):1948-57. PMID: 7560087.
      View in: PubMed
    269. Kalluri R, Wilson CB, Weber M, Gunwar S, Chonko AM, Neilson EG, Hudson BG. Identification of the alpha 3 chain of type IV collagen as the common autoantigen in antibasement membrane disease and Goodpasture syndrome. J Am Soc Nephrol. 1995 Oct; 6(4):1178-85. PMID: 8589284.
      View in: PubMed
    270. Kalluri R, van den Heuvel LP, Smeets HJ, Schroder CH, Lemmink HH, Boutaud A, Neilson EG, Hudson BG. A COL4A3 gene mutation and post-transplant anti-alpha 3(IV) collagen alloantibodies in Alport syndrome. Kidney Int. 1995 Apr; 47(4):1199-204. PMID: 7783419.
      View in: PubMed
    271. Kalluri R, Gattone VH, Noelken ME, Hudson BG. The alpha 3 chain of type IV collagen induces autoimmune Goodpasture syndrome. Proc Natl Acad Sci U S A. 1994 Jun 21; 91(13):6201-5. PMID: 8016138.
      View in: PubMed
    272. Ding J, Kashtan CE, Fan WW, Kleppel MM, Sun MJ, Kalluri R, Neilson EG, Michael AF. A monoclonal antibody marker for Alport syndrome identifies the Alport antigen as the alpha 5 chain of type IV collagen. Kidney Int. 1994 May; 45(5):1504-6. PMID: 8072264.
      View in: PubMed
    273. Hudson BG, Kalluri R, Tryggvason K. Pathology of glomerular basement membrane nephropathy. Curr Opin Nephrol Hypertens. 1994 May; 3(3):334-9. PMID: 7922261.
      View in: PubMed
    274. Kalluri R, Weber M, Netzer KO, Sun MJ, Neilson EG, Hudson BG. COL4A5 gene deletion and production of post-transplant anti-alpha 3(IV) collagen alloantibodies in Alport syndrome. Kidney Int. 1994 Mar; 45(3):721-6. PMID: 8196274.
      View in: PubMed
    275. Hudson BG, Kalluri R, Gunwar S, Noelken ME. Structure and organization of type IV collagen of renal glomerular basement membrane. Contrib Nephrol. 1994; 107:163-7. PMID: 8004963.
      View in: PubMed
    276. Noelken ME, Reddy GK, Kalluri R, Gunwar S, Hudson BG. The chain composition of aorta basement membrane collagen IV, localization of the chains in aorta and supramolecular assembly of the collagen IV protomers. Contrib Nephrol. 1994; 107:216-9. PMID: 8004971.
      View in: PubMed
    277. Reddy GK, Gunwar S, Kalluri R, Hudson BG, Noelken ME. Structure and composition of type IV collagen of bovine aorta. Biochim Biophys Acta. 1993 Jul 11; 1157(3):241-51. PMID: 8323954.
      View in: PubMed
    278. Neilson EG, Kalluri R, Sun MJ, Gunwar S, Danoff T, Mariyama M, Myers JC, Reeders ST, Hudson BG. Specificity of Goodpasture autoantibodies for the recombinant noncollagenous domains of human type IV collagen. J Biol Chem. 1993 Apr 25; 268(12):8402-5. PMID: 8473281.
      View in: PubMed
    279. Hudson BG, Kalluri R, Gunwar S, Noelken ME, Mariyama M, Reeders ST. Molecular characteristics of the Goodpasture autoantigen. Kidney Int. 1993 Jan; 43(1):135-9. PMID: 7679455.
      View in: PubMed
    280. Hudson BG, Kalluri R, Gunwar S, Weber M, Ballester F, Hudson JK, Noelken ME, Sarras M, Richardson WR, Saus J, et al. The pathogenesis of Alport syndrome involves type IV collagen molecules containing the alpha 3(IV) chain: evidence from anti-GBM nephritis after renal transplantation. Kidney Int. 1992 Jul; 42(1):179-87. PMID: 1635348.
      View in: PubMed
    281. Mariyama M, Kalluri R, Hudson BG, Reeders ST. The alpha 4(IV) chain of basement membrane collagen. Isolation of cDNAs encoding bovine alpha 4(IV) and comparison with other type IV collagens. J Biol Chem. 1992 Jan 15; 267(2):1253-8. PMID: 1370461.
      View in: PubMed
    282. Kalluri R, Gunwar S, Reeders ST, Morrison KC, Mariyama M, Ebner KE, Noelken ME, Hudson BG. Goodpasture syndrome. Localization of the epitope for the autoantibodies to the carboxyl-terminal region of the alpha 3(IV) chain of basement membrane collagen. J Biol Chem. 1991 Dec 15; 266(35):24018-24. PMID: 1721062.
      View in: PubMed
    283. Gunwar S, Ballester F, Kalluri R, Timoneda J, Chonko AM, Edwards SJ, Noelken ME, Hudson BG. Glomerular basement membrane. Identification of dimeric subunits of the noncollagenous domain (hexamer) of collagen IV and the Goodpasture antigen. J Biol Chem. 1991 Aug 15; 266(23):15318-24. PMID: 1869555.
      View in: PubMed
    284. Gunwar S, Bejarano PA, Kalluri R, Langeveld JP, Wisdom BJ, Noelken ME, Hudson BG. Alveolar basement membrane: molecular properties of the noncollagenous domain (hexamer) of collagen IV and its reactivity with Goodpasture autoantibodies. Am J Respir Cell Mol Biol. 1991 Aug; 5(2):107-12. PMID: 1892641.
      View in: PubMed
    285. Starting the scar. Nature Medicine. 17:1053.
    286. Partial Epithelial-to-Mesenchymal Transition and Other New Mechanisms of Kidney Fibrosis. Trends in Endocrinology and Metabolism.
    287. Possible mechanisms of kidney repair. Fibrogenesis and Tissue Repair. 2.
    288. Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure. American Journal of Pathology. 184:2687-2698.
    289. Erratum. Proceedings of the National Academy of Sciences of the United States of America. 91:9195.
    290. Endogenous inhibitors of angiogenesis. 215-231.
    291. Conversion of vascular endothelial cells into multipotent stem-like cells. Nature Medicine.
    292. Kidney International. 91:157-176.
    293. Epithelial-mesenchymal transitions - New insights into signaling, development and pathogenesis. Cells Tissues Organs. 185:5-6.
    294. The basics of epithelial-mesenchymal transition (The Journal of Clinical Investigation (2009) 119, 6, (1420-1428) DOI. Journal of Clinical Investigation. 120:1786.
    295. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine. 22:497-505.
    296. Cardiac fibrosis. 389-404.
    297. Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease. EBioMedicine. 2:19-36.
    298. Erratum. Nature Medicine. 17:514.
    299. The biology and function of exosomes in cancer. Journal of Clinical Investigation. 126:1208-1215.
    300. Erratum. Nature Cell Biology. 16:1125.
    301. Molecular and genetic basis of alport syndrome. 151-171.
    302. Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA. Nature Communications. 6.
    303. The biology and function of fibroblasts in cancer. Nature Reviews Cancer. 16:582-598.
    304. Erratum to Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival [Cancer Cell 25, 719-734; (2014)]. Cancer Cell. 28:831-833.
    305. Basement membrane derived inhibitors of angiogenesis. 121-127.
    306. Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis. Journal of Proteome Research. 14:5252-5262.
    307. Physiology of the renal interstitium. Clinical Journal of the American Society of Nephrology. 10:1831-1840.
    KALLURI's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description