TitleAssociate Professor
InstitutionMD Anderson
DepartmentMelanoma Medical Oncology
Address1400 Holcombe Blvd
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. White MG, Szczepaniak Sloane R, Witt RG, Reuben A, Gaudreau PO, Andrews MC, Feng N, Johnson S, Class CA, Bristow C, Wani K, Hudgens C, Nezi L, Manzo T, De Macedo MP, Hu J, Davis R, Jiang H, Prieto P, Burton E, Hwu P, Tawbi H, Gershenwald J, Lazar AJ, Tetzlaff MT, Overwijk W, Woodman SE, Cooper ZA, Marszalek JR, Davies MA, Heffernan TP, Wargo JA. Short-term treatment with multi-drug regimens combining BRAF/MEK-targeted therapy and immunotherapy results in durable responses in Braf-mutated melanoma. Oncoimmunology. 2021; 10(1):1992880. PMID: 34777916.
    2. Patel AB, Farooq S, Welborn M, Amaria RN, Chon SY, Diab A, Glitza Oliva IC, Huen AO, Li SQ, Nelson KC, Pacha O, Patel SP, Rapini RP, Tawbi HA, Wong MK, McQuade J, Davies MA, Haydu LE. Cutaneous adverse events in 155 patients with metastatic melanoma consecutively treated with anti-CTLA4 and anti-PD1 combination immunotherapy: Incidence, management, and clinical benefit. Cancer. 2021 Nov 01. PMID: 34724197.
      Citations:    Fields:    
    3. Sloane RAS, White MG, Witt RG, Banerjee A, Davies MA, Han G, Burton E, Ajami N, Simon JM, Bernatchez C, Haydu LE, Tawbi HA, Gershenwald JE, Keung E, Ross M, McQuade J, Amaria RN, Wani K, Lazar AJ, Woodman SE, Wang L, Andrews MC, Wargo JA. Identification of MicroRNA-mRNA Networks in Melanoma and Their Association with PD-1 Checkpoint Blockade Outcomes. Cancers (Basel). 2021 Oct 22; 13(21). PMID: 34771465.
    4. Andrews MC, Duong CPM, Gopalakrishnan V, Iebba V, Chen WS, Derosa L, Khan MAW, Cogdill AP, White MG, Wong MC, Ferrere G, Fluckiger A, Roberti MP, Opolon P, Alou MT, Yonekura S, Roh W, Spencer CN, Curbelo IF, Vence L, Reuben A, Johnson S, Arora R, Morad G, Lastrapes M, Baruch EN, Little L, Gumbs C, Cooper ZA, Prieto PA, Wani K, Lazar AJ, Tetzlaff MT, Hudgens CW, Callahan MK, Adamow M, Postow MA, Ariyan CE, Gaudreau PO, Nezi L, Raoult D, Mihalcioiu C, Elkrief A, Pezo RC, Haydu LE, Simon JM, Tawbi HA, McQuade J, Hwu P, Hwu WJ, Amaria RN, Burton EM, Woodman SE, Watowich S, Diab A, Patel SP, Glitza IC, Wong MK, Zhao L, Zhang J, Ajami NJ, Petrosino J, Jenq RR, Davies MA, Gershenwald JE, Futreal PA, Sharma P, Allison JP, Routy B, Zitvogel L, Wargo JA. Gut microbiota signatures are associated with toxicity to combined CTLA-4 and PD-1 blockade. Nat Med. 2021 08; 27(8):1432-1441. PMID: 34239137.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    5. Patel RR, He K, Barsoumian HB, Chang JY, Tang C, Verma V, Comeaux N, Chun SG, Gandhi S, Truong MT, Erasmus JJ, Hong DS, Lee PP, Ning MS, Nguyen QN, Heymach JV, Altan M, Blumenschein G, Fossella FV, Sezen D, Chen D, Carter BW, Davies MA, Glitza IC, Diab A, Ferrarotto R, Cabanillas ME, Yuan Y, Shah SJ, Parra ER, Sun B, Cortez MA, Welsh JW. High-dose irradiation in combination with non-ablative low-dose radiation to treat metastatic disease after progression on immunotherapy: Results of a phase II trial. Radiother Oncol. 2021 09; 162:60-67. PMID: 34237343.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    6. Li F, Deng L, Jackson KR, Talukder AH, Katailiha AS, Bradley SD, Zou Q, Chen C, Huo C, Chiu Y, Stair M, Feng W, Bagaev A, Kotlov N, Svekolkin V, Ataullakhanov R, Miheecheva N, Frenkel F, Wang Y, Zhang M, Hawke D, Han L, Zhou S, Zhang Y, Wang Z, Decker WK, Sonnemann HM, Roszik J, Forget MA, Davies MA, Bernatchez C, Yee C, Bassett R, Hwu P, Du X, Lizee G. Neoantigen vaccination induces clinical and immunologic responses in non-small cell lung cancer patients harboring EGFR mutations. J Immunother Cancer. 2021 07; 9(7). PMID: 34244308.
      Citations: 1     Fields:    
    7. Saberian C, Davies MA. Re-thinking therapeutic development for CNS metastatic disease. Exp Dermatol. 2021 Jun 21. PMID: 34152638.
      Citations:    Fields:    
    8. Saberian C, Amaria RN, Najjar AM, Radvanyi LG, Haymaker CL, Forget MA, Bassett RL, Faria SC, Glitza IC, Alvarez E, Parshottam S, Prieto V, Lizée G, Wong MK, McQuade JL, Diab A, Yee C, Tawbi HA, Patel S, Shpall EJ, Davies MA, Hwu P, Bernatchez C. Randomized phase II trial of lymphodepletion plus adoptive cell transfer of tumor-infiltrating lymphocytes, with or without dendritic cell vaccination, in patients with metastatic melanoma. J Immunother Cancer. 2021 05; 9(5). PMID: 34021033.
      Citations: 1     Fields:    
    9. Mitra D, Ologun G, Keung EZ, Goepfert RP, Amaria RN, Ross MI, Gershenwald JE, Lucci A, Fisher SB, Davies MA, Lee JE, Bishop AJ, Farooqi AS, Wargo J, Guadagnolo BA. Nodal Recurrence is a Primary Driver of Early Relapse for Patients with Sentinel Lymph Node-Positive Melanoma in the Modern Therapeutic Era. Ann Surg Oncol. 2021 Jul; 28(7):3480-3489. PMID: 33856603.
      Citations: 1     Fields:    Translation:Humans
    10. Haymaker C, Johnson DH, Murthy R, Bentebibel SE, Uemura MI, Hudgens CW, Safa H, James M, Andtbacka RHI, Johnson DB, Shaheen M, Davies MA, Rahimian S, Chunduru SK, Milton DR, Tetzlaff MT, Overwijk WW, Hwu P, Gabrail N, Agrawal S, Doolittle G, Puzanov I, Markowitz J, Bernatchez C, Diab A. Tilsotolimod with Ipilimumab Drives Tumor Responses in Anti-PD-1 Refractory Melanoma. Cancer Discov. 2021 Aug; 11(8):1996-2013. PMID: 33707233.
      Citations: 2     Fields:    
    11. Ogata D, Haydu LE, Glitza IC, Patel SP, Tawbi HA, McQuade JL, Diab A, Ekmekcioglu S, Wong MK, Davies MA, Amaria RN. The efficacy of anti-programmed cell death protein 1 therapy among patients with metastatic acral and metastatic mucosal melanoma. Cancer Med. 2021 04; 10(7):2293-2299. PMID: 33686688.
      Citations: 1     Fields:    Translation:Humans
    12. Ding Z, Ogata D, Roszik J, Qin Y, Kim SH, Tetzlaff MT, Lazar AJ, Davies MA, Ekmekcioglu S, Grimm EA. iNOS Associates With Poor Survival in Melanoma: A Role for Nitric Oxide in the PI3K-AKT Pathway Stimulation and PTEN S-Nitrosylation. Front Oncol. 2021; 11:631766. PMID: 33643925.
    13. Fischer GM, Guerrieri RA, Hu Q, Joon AY, Kumar S, Haydu LE, McQuade JL, Vashisht Gopal YN, Knighton B, Deng W, Hudgens CW, Lazar AJ, Tetzlaff MT, Davies MA. Clinical, molecular, metabolic, and immune features associated with oxidative phosphorylation in melanoma brain metastases. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdaa177. PMID: 33575655.
    14. Fukumura K, Malgulwar PB, Fischer GM, Hu X, Mao X, Song X, Hernandez SD, Zhang XH, Zhang J, Parra ER, Yu D, Debeb BG, Davies MA, Huse JT. Multi-omic molecular profiling reveals potentially targetable abnormalities shared across multiple histologies of brain metastasis. Acta Neuropathol. 2021 02; 141(2):303-321. PMID: 33394124.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    15. Zhao W, Li J, Chen MM, Luo Y, Ju Z, Nesser NK, Johnson-Camacho K, Boniface CT, Lawrence Y, Pande NT, Davies MA, Herlyn M, Muranen T, Zervantonakis IK, von Euw E, Schultz A, Kumar SV, Korkut A, Spellman PT, Akbani R, Slamon DJ, Gray JW, Brugge JS, Lu Y, Mills GB, Liang H. Large-Scale Characterization of Drug Responses of Clinically Relevant Proteins in Cancer Cell Lines. Cancer Cell. 2020 12 14; 38(6):829-843.e4. PMID: 33157050.
      Citations: 6     Fields:    Translation:HumansCells
    16. Fischer GM, Carapeto FCL, Joon AY, Haydu LE, Chen H, Wang F, Van Arnam JS, McQuade JL, Wani K, Kirkwood JM, Thompson JF, Tetzlaff MT, Lazar AJ, Tawbi HA, Gershenwald JE, Scolyer RA, Long GV, Davies MA. Molecular and immunological associations of elevated serum lactate dehydrogenase in metastatic melanoma patients: A fresh look at an old biomarker. Cancer Med. 2020 11; 9(22):8650-8661. PMID: 33016647.
      Citations: 1     Fields:    Translation:HumansCells
    17. Jaiswal AR, Liu AJ, Pudakalakatti S, Dutta P, Jayaprakash P, Bartkowiak T, Ager CR, Wang ZQ, Reuben A, Cooper ZA, Ivan C, Ju Z, Nwajei F, Wang J, Davies MA, Davis RE, Wargo JA, Bhattacharya PK, Hong DS, Curran MA. Melanoma Evolves Complete Immunotherapy Resistance through the Acquisition of a Hypermetabolic Phenotype. Cancer Immunol Res. 2020 11; 8(11):1365-1380. PMID: 32917656.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    18. Pundole X, Jones AL, Tetzlaff MT, Williams MD, Murphy WA, Otun A, Goepfert RP, Davies MA. Osteonecrosis of the jaw induced by treatment with anti-PD-1 immunotherapy: a case report. Immunotherapy. 2020 12; 12(17):1213-1219. PMID: 32900256.
      Citations:    Fields:    
    19. Mitra A, Andrews MC, Roh W, De Macedo MP, Hudgens CW, Carapeto F, Singh S, Reuben A, Wang F, Mao X, Song X, Wani K, Tippen S, Ng KS, Schalck A, Sakellariou-Thompson DA, Chen E, Reddy SM, Spencer CN, Wiesnoski D, Little LD, Gumbs C, Cooper ZA, Burton EM, Hwu P, Davies MA, Zhang J, Bernatchez C, Navin N, Sharma P, Allison JP, Wargo JA, Yee C, Tetzlaff MT, Hwu WJ, Lazar AJ, Futreal PA. Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma. Nat Commun. 2020 04 15; 11(1):1839. PMID: 32296058.
      Citations: 1     Fields:    Translation:Humans
    20. Davies MA. Is It Safe to Stop Anti-PD-1 Immunotherapy in Patients With Metastatic Melanoma Who Achieve a Complete Response? J Clin Oncol. 2020 05 20; 38(15):1645-1647. PMID: 32097093.
      Citations: 2     Fields:    Translation:Humans
    21. Lucci A, Hall CS, Patel SP, Narendran B, Bauldry JB, Royal RE, Karhade M, Upshaw JR, Wargo JA, Glitza IC, Wong MKK, Amaria RN, Tawbi HA, Diab A, Davies MA, Gershenwald JE, Lee JE, Hwu P, Ross MI. Circulating Tumor Cells and Early Relapse in Node-positive Melanoma. Clin Cancer Res. 2020 04 15; 26(8):1886-1895. PMID: 32015020.
      Citations: 11     Fields:    Translation:HumansCells
    22. Haydu LE, Lo SN, McQuade JL, Amaria RN, Wargo J, Ross MI, Cormier JN, Lucci A, Lee JE, Ferguson SD, Saw RPM, Spillane AJ, Shannon KF, Stretch JR, Hwu P, Patel SP, Diab A, Wong MKK, Glitza Oliva IC, Tawbi H, Carlino MS, Menzies AM, Long GV, Lazar AJ, Tetzlaff MT, Scolyer RA, Gershenwald JE, Thompson JF, Davies MA. Cumulative Incidence and Predictors of CNS Metastasis for Patients With American Joint Committee on Cancer 8th Edition Stage III Melanoma. J Clin Oncol. 2020 05 01; 38(13):1429-1441. PMID: 31990608.
      Citations: 3     Fields:    Translation:Humans
    23. Glitza IC, Smalley KSM, Brastianos PK, Davies MA, McCutcheon I, Liu JKC, Ahmed KA, Arrington JA, Evernden BR, Smalley I, Eroglu Z, Khushalani N, Margolin K, Kluger H, Atkins MB, Tawbi H, Boire A, Forsyth P. Leptomeningeal disease in melanoma patients: An update to treatment, challenges, and future directions. Pigment Cell Melanoma Res. 2020 07; 33(4):527-541. PMID: 31916400.
      Citations: 4     Fields:    Translation:HumansCells
    24. Helmink BA, Reddy SM, Gao J, Zhang S, Basar R, Thakur R, Yizhak K, Sade-Feldman M, Blando J, Han G, Gopalakrishnan V, Xi Y, Zhao H, Amaria RN, Tawbi HA, Cogdill AP, Liu W, LeBleu VS, Kugeratski FG, Patel S, Davies MA, Hwu P, Lee JE, Gershenwald JE, Lucci A, Arora R, Woodman S, Keung EZ, Gaudreau PO, Reuben A, Spencer CN, Burton EM, Haydu LE, Lazar AJ, Zapassodi R, Hudgens CW, Ledesma DA, Ong S, Bailey M, Warren S, Rao D, Krijgsman O, Rozeman EA, Peeper D, Blank CU, Schumacher TN, Butterfield LH, Zelazowska MA, McBride KM, Kalluri R, Allison J, Petitprez F, Fridman WH, Sautès-Fridman C, Hacohen N, Rezvani K, Sharma P, Tetzlaff MT, Wang L, Wargo JA. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020 01; 577(7791):549-555. PMID: 31942075.
      Citations: 340     Fields:    Translation:HumansCells
    25. Safa H, Johnson DH, Trinh VA, Rodgers TE, Lin H, Suarez-Almazor ME, Fa'ak F, Saberian C, Yee C, Davies MA, Tummala S, Woodman K, Abdel-Wahab N, Diab A. Immune checkpoint inhibitor related myasthenia gravis: single center experience and systematic review of the literature. J Immunother Cancer. 2019 11 21; 7(1):319. PMID: 31753014.
      Citations: 33     Fields:    Translation:Humans
    26. Gammon ST, Pisaneschi F, Bandi ML, Smith MG, Sun Y, Rao Y, Muller F, Wong F, De Groot J, Ackroyd J, Mawlawi O, Davies MA, Gopal YNV, Di Francesco ME, Marszalek JR, Dewhirst M, Piwnica-Worms D. Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [18F]FAZA PET In Vivo. Cells. 2019 11 21; 8(12). PMID: 31766580.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    27. Holbrook K, Lutzky J, Davies MA, Davis JM, Glitza IC, Amaria RN, Diab A, Patel SP, Amin A, Tawbi H. Intracranial antitumor activity with encorafenib plus binimetinib in patients with melanoma brain metastases: A case series. Cancer. 2020 02 01; 126(3):523-530. PMID: 31658370.
      Citations: 4     Fields:    Translation:Humans
    28. Nagarajan P, Piao J, Ning J, Noordenbos LE, Curry JL, Torres-Cabala CA, Diwan AH, Ivan D, Aung PP, Ross MI, Royal RE, Wargo JA, Wang WL, Samdani R, Lazar AJ, Rashid A, Davies MA, Prieto VG, Gershenwald JE, Tetzlaff MT. Prognostic model for patient survival in primary anorectal mucosal melanoma: stage at presentation determines relevance of histopathologic features. Mod Pathol. 2020 03; 33(3):496-513. PMID: 31383963.
      Citations: 2     Fields:    Translation:Humans
    29. Peng W, Williams LJ, Xu C, Melendez B, McKenzie JA, Chen Y, Jackson HL, Voo KS, Mbofung RM, Leahey SE, Wang J, Lizee G, Tawbi HA, Davies MA, Hoos A, Smothers J, Srinivasan R, Paul EM, Yanamandra N, Hwu P. Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8+ T Cells and Synergizes with PI3Kß Inhibition in PTEN Loss Melanoma. Clin Cancer Res. 2019 11 01; 25(21):6406-6416. PMID: 31371342.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    30. Amaria RN, Menzies AM, Burton EM, Scolyer RA, Tetzlaff MT, Antdbacka R, Ariyan C, Bassett R, Carter B, Daud A, Faries M, Fecher LA, Flaherty KT, Gershenwald JE, Hamid O, Hong A, Kirkwood JM, Lo S, Margolin K, Messina J, Postow MA, Rizos H, Ross MI, Rozeman EA, Saw RPM, Sondak V, Sullivan RJ, Taube JM, Thompson JF, van de Wiel BA, Eggermont AM, Davies MA, Ascierto PA, Spillane AJ, van Akkooi ACJ, Wargo JA, Blank CU, Tawbi HA, Long GV. Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium. Lancet Oncol. 2019 07; 20(7):e378-e389. PMID: 31267972.
      Citations: 31     Fields:    Translation:Humans
    31. Johnson DH, Zobniw CM, Trinh VA, Ma J, Bassett RL, Abdel-Wahab N, Anderson J, Davis JE, Joseph J, Uemura M, Noman A, Abu-Sbeih H, Yee C, Amaria R, Patel S, Tawbi H, Glitza IC, Davies MA, Wong MK, Woodman S, Hwu WJ, Hwu P, Wang Y, Diab A. Correction to: Infliximab associated with faster symptom resolution compared with corticosteroids alone for the management of immune-related enterocolitis. J Immunother Cancer. 2019 Apr 17; 7(1):107. PMID: 30995944.
      Citations:    Fields:    
    32. Ferguson SD, Bindal S, Bassett RL, Haydu LE, McCutcheon IE, Heimberger AB, Li J, O'Brien BJ, Guha-Thakurta N, Tetzlaff MT, Tawbi H, Davies MA, Glitza IC. Predictors of survival in metastatic melanoma patients with leptomeningeal disease (LMD). J Neurooncol. 2019 May; 142(3):499-509. PMID: 30847840.
      Citations: 6     Fields:    Translation:Humans
    33. Kluger HM, Margolin KA, Davies MA, Long GV, Tawbi HA, Goldberg SB, Chiang VL. Reply to A. Shinde et al. J Clin Oncol. 2019 04 20; 37(12):1031-1032. PMID: 30807233.
      Citations:    Fields:    Translation:Humans
    34. Fischer GM, Jalali A, Kircher DA, Lee WC, McQuade JL, Haydu LE, Joon AY, Reuben A, de Macedo MP, Carapeto FCL, Yang C, Srivastava A, Ambati CR, Sreekumar A, Hudgens CW, Knighton B, Deng W, Ferguson SD, Tawbi HA, Glitza IC, Gershenwald JE, Vashisht Gopal YN, Hwu P, Huse JT, Wargo JA, Futreal PA, Putluri N, Lazar AJ, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL, Tetzlaff MT, Davies MA. Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases. Cancer Discov. 2019 05; 9(5):628-645. PMID: 30787016.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    35. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA. Author Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. 2018 Dec; 24(12):1941. PMID: 30361510.
      Citations:    Fields:    
    36. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA. Publisher Correction: Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. 2018 Dec; 24(12):1942. PMID: 30361511.
      Citations: 2     Fields:    
    37. Vera-Aguilera J, Bedikian AY, Bassett RL, Hwu WJ, Kim KB, Qin Y, Cain S, Washington EW, Davies MA, Patel SM, Homsi J, Papadopoulos NE, Hwu P, Patel SP. Phase I/II Study of Hepatic Arterial Infusion of Nab-paclitaxel in Patients With Metastatic Melanoma to the Liver. Am J Clin Oncol. 2018 Nov; 41(11):1132-1136. PMID: 29509591.
      Citations:    Fields:    
    38. Johnson DH, Zobniw CM, Trinh VA, Ma J, Bassett RL, Abdel-Wahab N, Anderson J, Davis JE, Joseph J, Uemura M, Noman A, Abu-Sbeih H, Yee C, Amaria R, Patel S, Tawbi H, Glitza IC, Davies MA, Wong MK, Woodman S, Hwu WJ, Hwu P, Wang Y, Diab A. Infliximab associated with faster symptom resolution compared with corticosteroids alone for the management of immune-related enterocolitis. J Immunother Cancer. 2018 10 11; 6(1):103. PMID: 30305177.
      Citations: 35     Fields:    Translation:Humans
    39. Ferguson SD, Zheng S, Xiu J, Zhou S, Khasraw M, Brastianos PK, Kesari S, Hu J, Rudnick J, Salacz ME, Piccioni D, Huang S, Davies MA, Glitza IC, Heymach JV, Zhang J, Ibrahim NK, DeGroot JF, McCarty J, O'Brien BJ, Sawaya R, Verhaak RGW, Reddy SK, Priebe W, Gatalica Z, Spetzler D, Heimberger AB. Profiles of brain metastases: Prioritization of therapeutic targets. Int J Cancer. 2018 12 01; 143(11):3019-3026. PMID: 29923182.
      Citations: 11     Fields:    Translation:Humans
    40. Amaria RN, Reddy SM, Tawbi HA, Davies MA, Ross MI, Glitza IC, Cormier JN, Lewis C, Hwu WJ, Hanna E, Diab A, Wong MK, Royal R, Gross N, Weber R, Lai SY, Ehlers R, Blando J, Milton DR, Woodman S, Kageyama R, Wells DK, Hwu P, Patel SP, Lucci A, Hessel A, Lee JE, Gershenwald J, Simpson L, Burton EM, Posada L, Haydu L, Wang L, Zhang S, Lazar AJ, Hudgens CW, Gopalakrishnan V, Reuben A, Andrews MC, Spencer CN, Prieto V, Sharma P, Allison J, Tetzlaff MT, Wargo JA. Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat Med. 2018 11; 24(11):1649-1654. PMID: 30297909.
      Citations: 168     Fields:    Translation:HumansCTClinical Trials
    41. McQuade JL, Daniel CR, Hess KR, Davies MA. Sex as a predictor of response to cancer immunotherapy. Lancet Oncol. 2018 08; 19(8):e376. PMID: 30102226.
      Citations: 2     Fields:    Translation:Humans
    42. Liu Y, Lusk CM, Cho MH, Silverman EK, Qiao D, Zhang R, Scheurer ME, Kheradmand F, Wheeler DA, Tsavachidis S, Armstrong G, Zhu D, Wistuba II, Chow CB, Behrens C, Pikielny CW, Neslund-Dudas C, Pinney SM, Anderson M, Kupert E, Bailey-Wilson J, Gaba C, Mandal D, You M, de Andrade M, Yang P, Field JK, Liloglou T, Davies M, Lissowska J, Swiatkowska B, Zaridze D, Mukeriya A, Janout V, Holcatova I, Mates D, Milosavljevic S, Scelo G, Brennan P, McKay J, Liu G, Hung RJ, Christiani DC, Schwartz AG, Amos CI, Spitz MR. Rare Variants in Known Susceptibility Loci and Their Contribution to Risk of Lung Cancer. J Thorac Oncol. 2018 10; 13(10):1483-1495. PMID: 29981437.
      Citations: 9     Fields:    Translation:Humans
    43. Kwong LN, De Macedo MP, Haydu L, Joon AY, Tetzlaff MT, Calderone TL, Wu CJ, Kwong MK, Roszik J, Hess KR, Davies MA, Lazar AJ, Gershenwald JE. Biological Validation of RNA Sequencing Data from Formalin-Fixed Paraffin-Embedded Primary Melanomas. JCO Precis Oncol. 2018; 2018. PMID: 31058252.
      Citations: 8     
    44. Forget MA, Haymaker C, Hess KR, Meng YJ, Creasy C, Karpinets T, Fulbright OJ, Roszik J, Woodman SE, Kim YU, Sakellariou-Thompson D, Bhatta A, Wahl A, Flores E, Thorsen ST, Tavera RJ, Ramachandran R, Gonzalez AM, Toth CL, Wardell S, Mansaray R, Patel V, Carpio DJ, Vaughn C, Farinas CM, Velasquez PG, Hwu WJ, Patel SP, Davies MA, Diab A, Glitza IC, Tawbi H, Wong MK, Cain S, Ross MI, Lee JE, Gershenwald JE, Lucci A, Royal R, Cormier JN, Wargo JA, Radvanyi LG, Torres-Cabala CA, Beroukhim R, Hwu P, Amaria RN, Bernatchez C. Prospective Analysis of Adoptive TIL Therapy in Patients with Metastatic Melanoma: Response, Impact of Anti-CTLA4, and Biomarkers to Predict Clinical Outcome. Clin Cancer Res. 2018 09 15; 24(18):4416-4428. PMID: 29848573.
      Citations: 29     Fields:    Translation:HumansCells
    45. McQuade JL, Daniel CR, Davies MA. Body-mass index and metastatic melanoma outcomes - Authors' reply. Lancet Oncol. 2018 05; 19(5):e227-e228. PMID: 29726386.
      Citations: 2     Fields:    Translation:Humans
    46. Cascone T, McKenzie JA, Mbofung RM, Punt S, Wang Z, Xu C, Williams LJ, Wang Z, Bristow CA, Carugo A, Peoples MD, Li L, Karpinets T, Huang L, Malu S, Creasy C, Leahey SE, Chen J, Chen Y, Pelicano H, Bernatchez C, Gopal YNV, Heffernan TP, Hu J, Wang J, Amaria RN, Garraway LA, Huang P, Yang P, Wistuba II, Woodman SE, Roszik J, Davis RE, Davies MA, Heymach JV, Hwu P, Peng W. Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy. Cell Metab. 2018 May 01; 27(5):977-987.e4. PMID: 29628419.
      Citations: 133     Fields:    Translation:HumansAnimalsCells
    47. Huang L, Malu S, McKenzie JA, Andrews MC, Talukder AH, Tieu T, Karpinets T, Haymaker C, Forget MA, Williams LJ, Wang Z, Mbofung RM, Wang ZQ, Davis RE, Lo RS, Wargo JA, Davies MA, Bernatchez C, Heffernan T, Amaria RN, Korkut A, Peng W, Roszik J, Lizée G, Woodman SE, Hwu P. The RNA-binding Protein MEX3B Mediates Resistance to Cancer Immunotherapy by Downregulating HLA-A Expression. Clin Cancer Res. 2018 07 15; 24(14):3366-3376. PMID: 29496759.
      Citations: 24     Fields:    Translation:HumansCells
    48. Romano G, Chen PL, Song P, McQuade JL, Liang RJ, Liu M, Roh W, Duose DY, Carapeto FCL, Li J, Teh JLF, Aplin AE, Chen M, Zhang J, Lazar AJ, Davies MA, Futreal PA, Amaria RN, Zhang DY, Wargo JA, Kwong LN. A Preexisting Rare PIK3CAE545K Subpopulation Confers Clinical Resistance to MEK plus CDK4/6 Inhibition in NRAS Melanoma and Is Dependent on S6K1 Signaling. Cancer Discov. 2018 05; 8(5):556-567. PMID: 29496665.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    49. McQuade JL, Daniel CR, Hess KR, Mak C, Wang DY, Rai RR, Park JJ, Haydu LE, Spencer C, Wongchenko M, Lane S, Lee DY, Kaper M, McKean M, Beckermann KE, Rubinstein SM, Rooney I, Musib L, Budha N, Hsu J, Nowicki TS, Avila A, Haas T, Puligandla M, Lee S, Fang S, Wargo JA, Gershenwald JE, Lee JE, Hwu P, Chapman PB, Sosman JA, Schadendorf D, Grob JJ, Flaherty KT, Walker D, Yan Y, McKenna E, Legos JJ, Carlino MS, Ribas A, Kirkwood JM, Long GV, Johnson DB, Menzies AM, Davies MA. Association of body-mass index and outcomes in patients with metastatic melanoma treated with targeted therapy, immunotherapy, or chemotherapy: a retrospective, multicohort analysis. Lancet Oncol. 2018 03; 19(3):310-322. PMID: 29449192.
      Citations: 150     Fields:    Translation:Humans
    50. Glitza IC, Rohlfs M, Guha-Thakurta N, Bassett RL, Bernatchez C, Diab A, Woodman SE, Yee C, Amaria RN, Patel SP, Tawbi H, Wong M, Hwu WJ, Hwu P, Heimberger A, McCutcheon IE, Papadopoulos N, Davies MA. Retrospective review of metastatic melanoma patients with leptomeningeal disease treated with intrathecal interleukin-2. ESMO Open. 2018; 3(1):e000283. PMID: 29387478.
      Citations: 7     
    51. Amaria RN, Prieto PA, Tetzlaff MT, Reuben A, Andrews MC, Ross MI, Glitza IC, Cormier J, Hwu WJ, Tawbi HA, Patel SP, Lee JE, Gershenwald JE, Spencer CN, Gopalakrishnan V, Bassett R, Simpson L, Mouton R, Hudgens CW, Zhao L, Zhu H, Cooper ZA, Wani K, Lazar A, Hwu P, Diab A, Wong MK, McQuade JL, Royal R, Lucci A, Burton EM, Reddy S, Sharma P, Allison J, Futreal PA, Woodman SE, Davies MA, Wargo JA. Neoadjuvant plus adjuvant dabrafenib and trametinib versus standard of care in patients with high-risk, surgically resectable melanoma: a single-centre, open-label, randomised, phase 2 trial. Lancet Oncol. 2018 02; 19(2):181-193. PMID: 29361468.
      Citations: 43     Fields:    Translation:HumansCTClinical Trials
    52. Robinson JP, Rebecca VW, Kircher DA, Silvis MR, Smalley I, Gibney GT, Lastwika KJ, Chen G, Davies MA, Grossman D, Smalley KSM, Holmen SL, VanBrocklin MW. Resistance mechanisms to genetic suppression of mutant NRAS in melanoma. Melanoma Res. 2017 12; 27(6):545-557. PMID: 29076949.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    53. Davies MA, Flaherty KT. Melanoma in 2017: Moving treatments earlier to move further forwards. Nat Rev Clin Oncol. 2018 02; 15(2):75-76. PMID: 29182162.
      Citations: 2     Fields:    Translation:Humans
    54. Fischer GM, Vashisht Gopal YN, McQuade JL, Peng W, DeBerardinis RJ, Davies MA. Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications. Pigment Cell Melanoma Res. 2018 01; 31(1):11-30. PMID: 29049843.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    55. Tetzlaff MT, Jazaeri AA, Torres-Cabala CA, Korivi BR, Landon GA, Nagarajan P, Choksi A, Chen L, Uemura M, Aung PP, Diab A, Sharma P, Davies MA, Amaria R, Prieto VG, Curry JL. Erythema nodosum-like panniculitis mimicking disease recurrence: A novel toxicity from immune checkpoint blockade therapy-Report of 2 patients. J Cutan Pathol. 2017 Dec; 44(12):1080-1086. PMID: 28901560.
      Citations: 11     Fields:    Translation:Humans
    56. Davies MA, Saiag P, Long GV. Primary medical therapy for BRAFV600E-mutant melanoma brain metastases-is this good enough? - Authors' reply. Lancet Oncol. 2017 09; 18(9):e509. PMID: 28884697.
      Citations: 1     Fields:    Translation:Humans
    57. Reuben A, Petaccia de Macedo M, McQuade J, Joon A, Ren Z, Calderone T, Conner B, Wani K, Cooper ZA, Tawbi H, Tetzlaff MT, Padera RF, Durand JB, Lazar AJ, Wargo JA, Davies MA. Comparative immunologic characterization of autoimmune giant cell myocarditis with ipilimumab. Oncoimmunology. 2017; 6(12):e1361097. PMID: 29209563.
      Citations: 14     
    58. Davies MA, Saiag P, Robert C, Grob JJ, Flaherty KT, Arance A, Chiarion-Sileni V, Thomas L, Lesimple T, Mortier L, Moschos SJ, Hogg D, Márquez-Rodas I, Del Vecchio M, Lebbé C, Meyer N, Zhang Y, Huang Y, Mookerjee B, Long GV. Dabrafenib plus trametinib in patients with BRAFV600-mutant melanoma brain metastases (COMBI-MB): a multicentre, multicohort, open-label, phase 2 trial. Lancet Oncol. 2017 07; 18(7):863-873. PMID: 28592387.
      Citations: 143     Fields:    Translation:HumansCTClinical Trials
    59. Fang S, Wang Y, Dang Y, Gagel A, Ross MI, Gershenwald JE, Cormier JN, Wargo J, Haydu LE, Davies MA, McQuade JL, Sui D, Bassett RL, Reveille JD, Wei Q, Amos CI, Lee JE. Association between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes. J Invest Dermatol. 2017 08; 137(8):1792-1795. PMID: 28442307.
      Citations: 15     Fields:    Translation:Humans
    60. Reuben A, Spencer CN, Prieto PA, Gopalakrishnan V, Reddy SM, Miller JP, Mao X, De Macedo MP, Chen J, Song X, Jiang H, Chen PL, Beird HC, Garber HR, Roh W, Wani K, Chen E, Haymaker C, Forget MA, Little LD, Gumbs C, Thornton RL, Hudgens CW, Chen WS, Austin-Breneman J, Sloane RS, Nezi L, Cogdill AP, Bernatchez C, Roszik J, Hwu P, Woodman SE, Chin L, Tawbi H, Davies MA, Gershenwald JE, Amaria RN, Glitza IC, Diab A, Patel SP, Hu J, Lee JE, Grimm EA, Tetzlaff MT, Lazar AJ, Wistuba II, Clise-Dwyer K, Carter BW, Zhang J, Futreal PA, Sharma P, Allison JP, Cooper ZA, Wargo JA. Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma. NPJ Genom Med. 2017; 2. PMID: 28819565.
      Citations: 48     
    61. Roh W, Chen PL, Reuben A, Spencer CN, Prieto PA, Miller JP, Gopalakrishnan V, Wang F, Cooper ZA, Reddy SM, Gumbs C, Little L, Chang Q, Chen WS, Wani K, De Macedo MP, Chen E, Austin-Breneman JL, Jiang H, Roszik J, Tetzlaff MT, Davies MA, Gershenwald JE, Tawbi H, Lazar AJ, Hwu P, Hwu WJ, Diab A, Glitza IC, Patel SP, Woodman SE, Amaria RN, Prieto VG, Hu J, Sharma P, Allison JP, Chin L, Zhang J, Wargo JA, Futreal PA. Integrated molecular analysis of tumor biopsies on sequential CTLA-4 and PD-1 blockade reveals markers of response and resistance. Sci Transl Med. 2017 03 01; 9(379). PMID: 28251903.
      Citations: 226     Fields:    Translation:HumansCells
    62. Li J, Zhao W, Akbani R, Liu W, Ju Z, Ling S, Vellano CP, Roebuck P, Yu Q, Eterovic AK, Byers LA, Davies MA, Deng W, Gopal YN, Chen G, von Euw EM, Slamon D, Conklin D, Heymach JV, Gazdar AF, Minna JD, Myers JN, Lu Y, Mills GB, Liang H. Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays. Cancer Cell. 2017 02 13; 31(2):225-239. PMID: 28196595.
      Citations: 78     Fields:    Translation:HumansCells
    63. Tripp MK, Gershenwald JE, Davies MA, Garcia J, Gritz ER, Hawk ET, Peterson SK. Assessment of Compliance With Texas Legislation Banning Indoor UV Tanning by Minors. JAMA Dermatol. 2017 Feb 01; 153(2):228-229. PMID: 27829081.
      Citations: 6     Fields:    
    64. Glitza Oliva I, Tawbi H, Davies MA. Melanoma Brain Metastases: Current Areas of Investigation and Future Directions. Cancer J. 2017 Jan/Feb; 23(1):68-74. PMID: 28114258.
      Citations: 15     Fields:    Translation:Humans
    65. McQuade JL, Posada LP, Lecagoonporn S, Cain S, Bassett RL, Patel SP, Hwu WJ, Hwu P, Davies MA, Bedikian AY, Amaria RN. A phase I study of TPI 287 in combination with temozolomide for patients with metastatic melanoma. Melanoma Res. 2016 12; 26(6):604-608. PMID: 27540836.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    66. Nagarajan P, Curry JL, Ning J, Piao J, Torres-Cabala CA, Aung PP, Ivan D, Ross MI, Levenback CF, Frumovitz M, Gershenwald JE, Davies MA, Malpica A, Prieto VG, Tetzlaff MT. Tumor Thickness and Mitotic Rate Robustly Predict Melanoma-Specific Survival in Patients with Primary Vulvar Melanoma: A Retrospective Review of 100 Cases. Clin Cancer Res. 2017 04 15; 23(8):2093-2104. PMID: 27864417.
      Citations: 13     Fields:    Translation:Humans
    67. Roszik J, Haydu LE, Hess KR, Oba J, Joon AY, Siroy AE, Karpinets TV, Stingo FC, Baladandayuthapani V, Tetzlaff MT, Wargo JA, Chen K, Forget MA, Haymaker CL, Chen JQ, Meric-Bernstam F, Eterovic AK, Shaw KR, Mills GB, Gershenwald JE, Radvanyi LG, Hwu P, Futreal PA, Gibbons DL, Lazar AJ, Bernatchez C, Davies MA, Woodman SE. Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set. BMC Med. 2016 10 25; 14(1):168. PMID: 27776519.
      Citations: 47     Fields:    Translation:HumansCells
    68. Tetzlaff MT, Singh RR, Seviour EG, Curry JL, Hudgens CW, Bell D, Wimmer DA, Ning J, Czerniak BA, Zhang L, Davies MA, Prieto VG, Broaddus RR, Ram P, Luthra R, Esmaeli B. Next-generation sequencing identifies high frequency of mutations in potentially clinically actionable genes in sebaceous carcinoma. J Pathol. 2016 09; 240(1):84-95. PMID: 27287813.
      Citations: 14     Fields:    Translation:HumansCells
    69. Chen G, McQuade JL, Panka DJ, Hudgens CW, Amin-Mansour A, Mu XJ, Bahl S, Jané-Valbuena J, Wani KM, Reuben A, Creasy CA, Jiang H, Cooper ZA, Roszik J, Bassett RL, Joon AY, Simpson LM, Mouton RD, Glitza IC, Patel SP, Hwu WJ, Amaria RN, Diab A, Hwu P, Lazar AJ, Wargo JA, Garraway LA, Tetzlaff MT, Sullivan RJ, Kim KB, Davies MA. Clinical, Molecular, and Immune Analysis of Dabrafenib-Trametinib Combination Treatment for BRAF Inhibitor-Refractory Metastatic Melanoma: A Phase 2 Clinical Trial. JAMA Oncol. 2016 Aug 01; 2(8):1056-64. PMID: 27124486.
      Citations: 15     Fields:    Translation:HumansCellsCTClinical Trials
    70. Chen PL, Roh W, Reuben A, Cooper ZA, Spencer CN, Prieto PA, Miller JP, Bassett RL, Gopalakrishnan V, Wani K, De Macedo MP, Austin-Breneman JL, Jiang H, Chang Q, Reddy SM, Chen WS, Tetzlaff MT, Broaddus RJ, Davies MA, Gershenwald JE, Haydu L, Lazar AJ, Patel SP, Hwu P, Hwu WJ, Diab A, Glitza IC, Woodman SE, Vence LM, Wistuba II, Amaria RN, Kwong LN, Prieto V, Davis RE, Ma W, Overwijk WW, Sharpe AH, Hu J, Futreal PA, Blando J, Sharma P, Allison JP, Chin L, Wargo JA. Analysis of Immune Signatures in Longitudinal Tumor Samples Yields Insight into Biomarkers of Response and Mechanisms of Resistance to Immune Checkpoint Blockade. Cancer Discov. 2016 08; 6(8):827-37. PMID: 27301722.
      Citations: 304     Fields:    Translation:HumansCells
    71. Loghavi S, Routbort MJ, Patel KP, Luthra R, Wang WL, Broaddus RR, Davies MA, Lazar AJ. How Do We Make Clinical Molecular Testing for Cancer Standard of Care for Pathology Departments? J Natl Compr Canc Netw. 2016 06; 14(6):787-92. PMID: 27283170.
      Citations:    Fields:    Translation:Humans
    72. Cooper ZA, Reuben A, Spencer CN, Prieto PA, Austin-Breneman JL, Jiang H, Haymaker C, Gopalakrishnan V, Tetzlaff MT, Frederick DT, Sullivan RJ, Amaria RN, Patel SP, Hwu P, Woodman SE, Glitza IC, Diab A, Vence LM, Rodriguez-Canales J, Parra ER, Wistuba II, Coussens LM, Sharpe AH, Flaherty KT, Gershenwald JE, Chin L, Davies MA, Clise-Dwyer K, Allison JP, Sharma P, Wargo JA. Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma. Oncoimmunology. 2016 Mar; 5(3):e1136044. PMID: 27141370.
      Citations: 23     
    73. Roszik J, Wu CJ, Siroy AE, Lazar AJ, Davies MA, Woodman SE, Kwong LN. Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression. Sci Rep. 2016 Jan 20; 6:19649. PMID: 26787600.
      Citations: 5     Fields:    Translation:Humans
    74. Ekmekcioglu S, Davies MA, Tanese K, Roszik J, Shin-Sim M, Bassett RL, Milton DR, Woodman SE, Prieto VG, Gershenwald JE, Morton DL, Hoon DS, Grimm EA. Inflammatory Marker Testing Identifies CD74 Expression in Melanoma Tumor Cells, and Its Expression Associates with Favorable Survival for Stage III Melanoma. Clin Cancer Res. 2016 06 15; 22(12):3016-24. PMID: 26783288.
      Citations: 19     Fields:    Translation:Humans
    75. O'Connell SE, Jackson BR, Edwardson CL, Yates T, Biddle SJ, Davies MJ, Dunstan D, Esliger D, Gray L, Miller P, Munir F. Providing NHS staff with height-adjustable workstations and behaviour change strategies to reduce workplace sitting time: protocol for the Stand More AT (SMArT) Work cluster randomised controlled trial. BMC Public Health. 2015 Dec 09; 15:1219. PMID: 26646026.
      Citations: 15     Fields:    Translation:Humans
    76. Peng W, Chen JQ, Liu C, Malu S, Creasy C, Tetzlaff MT, Xu C, McKenzie JA, Zhang C, Liang X, Williams LJ, Deng W, Chen G, Mbofung R, Lazar AJ, Torres-Cabala CA, Cooper ZA, Chen PL, Tieu TN, Spranger S, Yu X, Bernatchez C, Forget MA, Haymaker C, Amaria R, McQuade JL, Glitza IC, Cascone T, Li HS, Kwong LN, Heffernan TP, Hu J, Bassett RL, Bosenberg MW, Woodman SE, Overwijk WW, Lizée G, Roszik J, Gajewski TF, Wargo JA, Gershenwald JE, Radvanyi L, Davies MA, Hwu P. Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy. Cancer Discov. 2016 Feb; 6(2):202-16. PMID: 26645196.
      Citations: 449     Fields:    Translation:HumansAnimalsCells
    77. Davies MA. Molecular approaches to tumor inhibition in melanoma. Clin Adv Hematol Oncol. 2015 Dec; 13(12):831-3. PMID: 27058849.
      Citations:    Fields:    Translation:HumansAnimals
    78. Piercy J, Milligan G, Davies MJ, Detournay B, Orozco Beltran D, Chubb B, Bottomley JM, Nicolucci A, Jacob S. The Relationship Between Glucose-Lowering Medications, Adherence, and Outcomes in Patients with Type 2 Diabetes. Value Health. 2015 Nov; 18(7):A343. PMID: 26531941.
    79. Glitza IC, Haymaker C, Bernatchez C, Vence L, Rohlfs M, Richard J, Lacey C, Mansaray R, Fulbright OJ, Ramachandran R, Toth C, Wardell S, Patel SP, Woodman SE, Hwu WJ, Radvanyi LG, Davies MA, Papadopoulos NE, Hwu P. Intrathecal Administration of Tumor-Infiltrating Lymphocytes Is Well Tolerated in a Patient with Leptomeningeal Disease from Metastatic Melanoma: A Case Report. Cancer Immunol Res. 2015 Nov; 3(11):1201-6. PMID: 26216417.
      Citations: 12     Fields:    Translation:HumansCells
    80. Capparelli C, Rosenbaum S, Berman-Booty LD, Salhi A, Gaborit N, Zhan T, Chervoneva I, Roszik J, Woodman SE, Davies MA, Setiady YY, Osman I, Yarden Y, Aplin AE. ErbB3-ErbB2 Complexes as a Therapeutic Target in a Subset of Wild-type BRAF/NRAS Cutaneous Melanomas. Cancer Res. 2015 Sep 01; 75(17):3554-67. PMID: 26206558.
      Citations: 8     Fields:    Translation:HumansCells
    81. Hong DS, Kurzrock R, Wheler JJ, Naing A, Falchook GS, Fu S, Kim KB, Davies MA, Nguyen LM, George GC, Xu L, Shumaker R, Ren M, Mink J, Bedell C, Andresen C, Sachdev P, O'Brien JP, Nemunaitis J. Phase I Dose-Escalation Study of the Multikinase Inhibitor Lenvatinib in Patients with Advanced Solid Tumors and in an Expanded Cohort of Patients with Melanoma. Clin Cancer Res. 2015 Nov 01; 21(21):4801-10. PMID: 26169970.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    82. Davies MA. BRAF in early stage melanoma: rationale for testing and treatment? Br J Dermatol. 2015 Jul; 173(1):9-10. PMID: 26174638.
      Citations:    Fields:    Translation:Humans
    83. Meric-Bernstam F, Brusco L, Shaw K, Horombe C, Kopetz S, Davies MA, Routbort M, Piha-Paul SA, Janku F, Ueno N, Hong D, De Groot J, Ravi V, Li Y, Luthra R, Patel K, Broaddus R, Mendelsohn J, Mills GB. Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials. J Clin Oncol. 2015 Sep 01; 33(25):2753-62. PMID: 26014291.
      Citations: 168     Fields:    Translation:Humans
    84. Giles LC, Whitrow MJ, Davies MJ, Davies CE, Rumbold AR, Moore VM. Growth trajectories in early childhood, their relationship with antenatal and postnatal factors, and development of obesity by age 9 years: results from an Australian birth cohort study. Int J Obes (Lond). 2015 Jul; 39(7):1049-56. PMID: 26008137.
      Citations: 25     Fields:    Translation:Humans
    85. Indo HP, Matsui H, Chen J, Zhu H, Hawkins CL, Davies MJ, Yarana C, St Clair DK, Majima HJ. Manganese superoxide dismutase promotes interaction of actin, S100A4 and Talin, and enhances rat gastric tumor cell invasion. J Clin Biochem Nutr. 2015 Jul; 57(1):13-20. PMID: 26236095.
      Citations: 1     
    86. Tetzlaff MT, Pattanaprichakul P, Wargo J, Fox PS, Patel KP, Estrella JS, Broaddus RR, Williams MD, Davies MA, Routbort MJ, Lazar AJ, Woodman SE, Hwu WJ, Gershenwald JE, Prieto VG, Torres-Cabala CA, Curry JL. Utility of BRAF V600E Immunohistochemistry Expression Pattern as a Surrogate of BRAF Mutation Status in 154 Patients with Advanced Melanoma. Hum Pathol. 2015 Aug; 46(8):1101-10. PMID: 26058727.
      Citations: 12     Fields:    Translation:Humans
    87. Davies MA. Role and complexity of next-generation sequencing in melanoma. Cancer Cytopathol. 2015 Jun; 123(6):329-30. PMID: 25877344.
      Citations:    Fields:    Translation:Humans
    88. Meric-Bernstam F, Johnson A, Holla V, Bailey AM, Brusco L, Chen K, Routbort M, Patel KP, Zeng J, Kopetz S, Davies MA, Piha-Paul SA, Hong DS, Eterovic AK, Tsimberidou AM, Broaddus R, Bernstam EV, Shaw KR, Mendelsohn J, Mills GB. A decision support framework for genomically informed investigational cancer therapy. J Natl Cancer Inst. 2015 Jul; 107(7). PMID: 25863335.
      Citations: 82     Fields:    Translation:HumansAnimals
    89. Stockman DL, Curry JL, Torres-Cabala CA, Watson IR, Siroy AE, Bassett RL, Zou L, Patel KP, Luthra R, Davies MA, Wargo JA, Routbort MA, Broaddus RR, Prieto VG, Lazar AJ, Tetzlaff MT. Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations. J Cutan Pathol. 2015 May; 42(5):308-17. PMID: 25754356.
      Citations: 5     Fields:    Translation:HumansCells
    90. Bradley SD, Chen Z, Melendez B, Talukder A, Khalili JS, Rodriguez-Cruz T, Liu S, Whittington M, Deng W, Li F, Bernatchez C, Radvanyi LG, Davies MA, Hwu P, Lizée G. BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of Melanoma. Cancer Immunol Res. 2015 Jun; 3(6):602-9. PMID: 25795007.
      Citations: 60     Fields:    Translation:HumansCells
    91. Zaccardi F, Webb DR, Carter P, Pitocco D, Khunti K, Davies MJ, Kurl S, Laukkanen JA. Association between direct measurement of active serum calcium and risk of type 2 diabetes mellitus: A prospective study. Nutr Metab Cardiovasc Dis. 2015 Jun; 25(6):562-8. PMID: 25933474.
      Citations: 2     Fields:    Translation:Humans
    92. Goswami RS, Patel KP, Singh RR, Meric-Bernstam F, Kopetz ES, Subbiah V, Alvarez RH, Davies MA, Jabbar KJ, Roy-Chowdhuri S, Lazar AJ, Medeiros LJ, Broaddus RR, Luthra R, Routbort MJ. Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors. Clin Cancer Res. 2015 Jun 01; 21(11):2644-51. PMID: 25695693.
      Citations: 34     Fields:    Translation:Humans
    93. Tunceli K, Zhao C, Davies MJ, Brodovicz KG, Alexander CM, Iglay K, Radican L. Factors associated with adherence to oral antihyperglycemic monotherapy in patients with type 2 diabetes. Patient Prefer Adherence. 2015; 9:191-7. PMID: 25670888.
      Citations: 13     
    94. Chen K, Meric-Bernstam F, Zhao H, Zhang Q, Ezzeddine N, Tang LY, Qi Y, Mao Y, Chen T, Chong Z, Zhou W, Zheng X, Johnson A, Aldape KD, Routbort MJ, Luthra R, Kopetz S, Davies MA, de Groot J, Moulder S, Vinod R, Farhangfar CJ, Shaw KM, Mendelsohn J, Mills GB, Eterovic AK. Clinical actionability enhanced through deep targeted sequencing of solid tumors. Clin Chem. 2015 Mar; 61(3):544-53. PMID: 25626406.
      Citations: 53     Fields:    Translation:Humans
    95. Hauber AB, Tunceli K, Yang JC, Gantz I, Brodovicz KG, Alexander CM, Davies MJ, Radican L. A survey of patient preferences for oral antihyperglycemic therapy in patients with type 2 diabetes mellitus. Diabetes Ther. 2015 Mar; 6(1):75-84. PMID: 25586555.
      Citations: 17     
    96. McQuade J, Davies MA. Converting biology into clinical benefit: lessons learned from BRAF inhibitors. Melanoma Manag. 2015; 2(3):241-254. PMID: 26594316.
      Citations: 3     
    97. Patel N, Stone MA, McDonough C, Davies MJ, Khunti K, Eborall H. Concerns and perceptions about necessity in relation to insulin therapy in an ethnically diverse UK population with Type 2 diabetes: a qualitative study focusing mainly on people of South Asian origin. Diabet Med. 2015 May; 32(5):635-44. PMID: 25439281.
      Citations: 5     Fields:    Translation:Humans
    98. Maftei O, Whitrow MJ, Davies MJ, Giles LC, Owens JA, Moore VM. Maternal body size prior to pregnancy, gestational diabetes and weight gain: associations with insulin resistance in children at 9-10 years. Diabet Med. 2015 Feb; 32(2):174-80. PMID: 25407383.
      Citations: 12     Fields:    Translation:Humans
    99. Ju Z, Liu W, Roebuck PL, Siwak DR, Zhang N, Lu Y, Davies MA, Akbani R, Weinstein JN, Mills GB, Coombes KR. Development of a robust classifier for quality control of reverse-phase protein arrays. Bioinformatics. 2015 Mar 15; 31(6):912-8. PMID: 25380958.
      Citations: 18     Fields:    
    100. Dallosso HM, Bodicoat DH, Campbell M, Carey ME, Davies MJ, Eborall HC, Hadjiconstantinou M, Khunti K, Speight J, Heller S. Self-monitoring of blood glucose versus self-monitoring of urine glucose in adults with newly diagnosed Type 2 diabetes receiving structured education: a cluster randomized controlled trial. Diabet Med. 2015 Mar; 32(3):414-22. PMID: 25308625.
      Citations: 6     Fields:    Translation:Humans
    101. Zafar A, Stone MA, Davies MJ, Khunti K. Acknowledging and allocating responsibility for clinical inertia in the management of Type 2 diabetes in primary care: a qualitative study. Diabet Med. 2015 Mar; 32(3):407-13. PMID: 25251768.
      Citations: 28     Fields:    Translation:Humans
    102. Gopal YN, Rizos H, Chen G, Deng W, Frederick DT, Cooper ZA, Scolyer RA, Pupo G, Komurov K, Sehgal V, Zhang J, Patel L, Pereira CG, Broom BM, Mills GB, Ram P, Smith PD, Wargo JA, Long GV, Davies MA. Inhibition of mTORC1/2 overcomes resistance to MAPK pathway inhibitors mediated by PGC1a and oxidative phosphorylation in melanoma. Cancer Res. 2014 Dec 01; 74(23):7037-47. PMID: 25297634.
      Citations: 79     Fields:    Translation:HumansCells
    103. Mandalia PK, Stone MA, Davies MJ, Khunti K, Carey ME. Diabetes self-management education: acceptability of using trained lay educators. Postgrad Med J. 2014 Nov; 90(1069):638-42. PMID: 25258417.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    104. Glitza IC, Davies MA. Genotyping of cutaneous melanoma. Chin Clin Oncol. 2014 Sep; 3(3):27. PMID: 25632386.
      Citations: 6     Fields:    
    105. Bucheit AD, Chen G, Siroy A, Tetzlaff M, Broaddus R, Milton D, Fox P, Bassett R, Hwu P, Gershenwald JE, Lazar AJ, Davies MA. Complete loss of PTEN protein expression correlates with shorter time to brain metastasis and survival in stage IIIB/C melanoma patients with BRAFV600 mutations. Clin Cancer Res. 2014 Nov 01; 20(21):5527-36. PMID: 25165098.
      Citations: 55     Fields:    Translation:Humans
    106. Siroy AE, Boland GM, Milton DR, Roszik J, Frankian S, Malke J, Haydu L, Prieto VG, Tetzlaff M, Ivan D, Wang WL, Torres-Cabala C, Curry J, Roy-Chowdhuri S, Broaddus R, Rashid A, Stewart J, Gershenwald JE, Amaria RN, Patel SP, Papadopoulos NE, Bedikian A, Hwu WJ, Hwu P, Diab A, Woodman SE, Aldape KD, Luthra R, Patel KP, Shaw KR, Mills GB, Mendelsohn J, Meric-Bernstam F, Kim KB, Routbort MJ, Lazar AJ, Davies MA. Beyond BRAF(V600): clinical mutation panel testing by next-generation sequencing in advanced melanoma. J Invest Dermatol. 2015 Feb; 135(2):508-515. PMID: 25148578.
      Citations: 48     Fields:    Translation:Humans
    107. Alrwas A, Papadopoulos NE, Cain S, Patel SP, Kim KB, Deburr TL, Bassett R, Hwu WJ, Bedikian AY, Davies MA, Woodman SE, Hwu P. Phase I trial of biochemotherapy with cisplatin, temozolomide, and dose escalation of nab-paclitaxel combined with interleukin-2 and interferon-a in patients with metastatic melanoma. Melanoma Res. 2014 Aug; 24(4):342-8. PMID: 24743052.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    108. Watson IR, Li L, Cabeceiras PK, Mahdavi M, Gutschner T, Genovese G, Wang G, Fang Z, Tepper JM, Stemke-Hale K, Tsai KY, Davies MA, Mills GB, Chin L. The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF. Cancer Res. 2014 Sep 01; 74(17):4845-4852. PMID: 25056119.
      Citations: 64     Fields:    Translation:HumansCells
    109. Chen G, Davies MA. Targeted therapy resistance mechanisms and therapeutic implications in melanoma. Hematol Oncol Clin North Am. 2014 Jun; 28(3):523-36. PMID: 24880945.
      Citations: 10     Fields:    Translation:HumansCells
    110. Dutton-Regester K, Gartner JJ, Emmanuel R, Qutob N, Davies MA, Gershenwald JE, Robinson W, Robinson S, Rosenberg SA, Scolyer RA, Mann GJ, Thompson JF, Hayward NK, Samuels Y. A highly recurrent RPS27 5'UTR mutation in melanoma. Oncotarget. 2014 May 30; 5(10):2912-7. PMID: 24913145.
      Citations: 26     Fields:    Translation:HumansCells
    111. Carey ME, Mandalia PK, Daly H, Gray LJ, Hale R, Martin Stacey L, Taub N, Skinner TC, Stone M, Heller S, Khunti K, Davies MJ. Increasing capacity to deliver diabetes self-management education: results of the DESMOND lay educator non-randomized controlled equivalence trial. Diabet Med. 2014 Nov; 31(11):1431-8. PMID: 24798205.
      Citations: 7     Fields:    Translation:Humans
    112. Skinner TC, Khunti K, Carey ME, Dallosso H, Heller S, Davies MJ. Stability and predictive utility, over 3 years, of the illness beliefs of individuals recently diagnosed with Type 2 diabetes mellitus. Diabet Med. 2014 Oct; 31(10):1260-3. PMID: 24798395.
      Citations: 6     Fields:    Translation:Humans
    113. Davies MJ, Gross JL, Ono Y, Sasaki T, Bantwal G, Gall MA, Niemeyer M, Seino H. Efficacy and safety of insulin degludec given as part of basal-bolus treatment with mealtime insulin aspart in type 1 diabetes: a 26-week randomized, open-label, treat-to-target non-inferiority trial. Diabetes Obes Metab. 2014 Oct; 16(10):922-30. PMID: 24702700.
      Citations: 17     Fields:    Translation:Humans
    114. Chen G, Chakravarti N, Aardalen K, Lazar AJ, Tetzlaff MT, Wubbenhorst B, Kim SB, Kopetz S, Ledoux AA, Gopal YN, Pereira CG, Deng W, Lee JS, Nathanson KL, Aldape KD, Prieto VG, Stuart D, Davies MA. Molecular profiling of patient-matched brain and extracranial melanoma metastases implicates the PI3K pathway as a therapeutic target. Clin Cancer Res. 2014 Nov 01; 20(21):5537-46. PMID: 24803579.
      Citations: 58     Fields:    Translation:HumansCells
    115. Davies MA. Finding the right balance of BRAF inhibition in melanoma. Cancer Discov. 2014 May; 4(5):510-2. PMID: 24795008.
      Citations: 1     Fields:    Translation:Humans
    116. Chen M, Wu L, Zhao J, Wu F, Davies MJ, Wittert GA, Norman RJ, Robker RL, Heilbronn LK. Altered glucose metabolism in mouse and humans conceived by IVF. Diabetes. 2014 Oct; 63(10):3189-98. PMID: 24760136.
      Citations: 22     Fields:    Translation:HumansAnimalsCTClinical Trials
    117. Galougahi KK, Liu CC, Gentile C, Kok C, Nunez A, Garcia A, Fry NA, Davies MJ, Hawkins CL, Rasmussen HH, Figtree GA. Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction. J Am Heart Assoc. 2014 Apr 22; 3(2):e000731. PMID: 24755153.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    118. Chuang CY, Degendorfer G, Hammer A, Whitelock JM, Malle E, Davies MJ. Oxidation modifies the structure and function of the extracellular matrix generated by human coronary artery endothelial cells. Biochem J. 2014 Apr 15; 459(2):313-22. PMID: 24517414.
      Citations: 8     Fields:    Translation:HumansCells
    119. Round EM, Engel SS, Golm GT, Davies MJ, Kaufman KD, Goldstein BJ. Safety of sitagliptin in elderly patients with type 2 diabetes: a pooled analysis of 25 clinical studies. Drugs Aging. 2014 Mar; 31(3):203-14. PMID: 24510656.
      Citations: 7     Fields:    Translation:Humans
    120. Ma XH, Piao SF, Dey S, McAfee Q, Karakousis G, Villanueva J, Hart LS, Levi S, Hu J, Zhang G, Lazova R, Klump V, Pawelek JM, Xu X, Xu W, Schuchter LM, Davies MA, Herlyn M, Winkler J, Koumenis C, Amaravadi RK. Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma. J Clin Invest. 2014 Mar; 124(3):1406-17. PMID: 24569374.
      Citations: 172     Fields:    Translation:HumansAnimalsCells
    121. Gad NA, Mizdrak J, Pattison DI, Davies MJ, Truscott RJ, Jamie JF. Detection, quantification, and total synthesis of novel 3-hydroxykynurenine glucoside-derived metabolites present in human lenses. Invest Ophthalmol Vis Sci. 2014 Feb 10; 55(2):849-55. PMID: 24408982.
      Citations: 1     Fields:    Translation:Humans
    122. Lord MS, Chuang CY, Melrose J, Davies MJ, Iozzo RV, Whitelock JM. The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling. Matrix Biol. 2014 Apr; 35:112-22. PMID: 24509440.
      Citations: 48     Fields:    Translation:HumansCells
    123. Brady EM, Davies MJ, Gray LJ, Saeed MA, Smith D, Hanif W, Khunti K. A randomized controlled trial comparing the GLP-1 receptor agonist liraglutide to a sulphonylurea as add on to metformin in patients with established type 2 diabetes during Ramadan: the Treat 4 Ramadan Trial. Diabetes Obes Metab. 2014 Jun; 16(6):527-36. PMID: 24373063.
      Citations: 18     Fields:    Translation:Humans
    124. Morgan PE, Sheahan PJ, Davies MJ. Perturbation of human coronary artery endothelial cell redox state and NADPH generation by methylglyoxal. PLoS One. 2014; 9(1):e86564. PMID: 24466151.
      Citations: 5     Fields:    Translation:HumansCells
    125. Marino JL, Moore VM, Willson KJ, Rumbold A, Whitrow MJ, Giles LC, Davies MJ. Perinatal outcomes by mode of assisted conception and sub-fertility in an Australian data linkage cohort. PLoS One. 2014; 9(1):e80398. PMID: 24416127.
      Citations: 24     Fields:    Translation:Humans
    126. Lopez-Rivera E, Jayaraman P, Parikh F, Davies MA, Ekmekcioglu S, Izadmehr S, Milton DR, Chipuk JE, Grimm EA, Estrada Y, Aguirre-Ghiso J, Sikora AG. Inducible nitric oxide synthase drives mTOR pathway activation and proliferation of human melanoma by reversible nitrosylation of TSC2. Cancer Res. 2014 Feb 15; 74(4):1067-78. PMID: 24398473.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    127. Curry JL, Davies MA, Calderone TL, Nathanson K, Prieto VG, Gershenwald JE. Tissue resources for clinical use and marker studies in melanoma. Methods Mol Biol. 2014; 1102:679-95. PMID: 24259006.
      Citations: 2     Fields:    Translation:HumansCells
    128. Talib J, Kwan J, Suryo Rahmanto A, Witting PK, Davies MJ. The smoking-associated oxidant hypothiocyanous acid induces endothelial nitric oxide synthase dysfunction. Biochem J. 2014 Jan 01; 457(1):89-97. PMID: 24112082.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    129. Bucheit AD, Davies MA. Emerging insights into resistance to BRAF inhibitors in melanoma. Biochem Pharmacol. 2014 Feb 01; 87(3):381-9. PMID: 24291778.
      Citations: 46     Fields:    Translation:Humans
    130. Steele EJ, Giles LC, Davies MJ, Moore VM. Is precarious employment associated with women remaining childless until age 35 years? Results from an Australian birth cohort study. Hum Reprod. 2014 Jan; 29(1):155-60. PMID: 24254416.
      Citations:    Fields:    Translation:Humans
    131. Dunn LL, Simpson PJ, Prosser HC, Lecce L, Yuen GS, Buckle A, Sieveking DP, Vanags LZ, Lim PR, Chow RW, Lam YT, Clayton Z, Bao S, Davies MJ, Stadler N, Celermajer DS, Stocker R, Bursill CA, Cooke JP, Ng MK. A critical role for thioredoxin-interacting protein in diabetes-related impairment of angiogenesis. Diabetes. 2014 Feb; 63(2):675-87. PMID: 24198286.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    132. Lloyd MM, Grima MA, Rayner BS, Hadfield KA, Davies MJ, Hawkins CL. Comparative reactivity of the myeloperoxidase-derived oxidants hypochlorous acid and hypothiocyanous acid with human coronary artery endothelial cells. Free Radic Biol Med. 2013 Dec; 65:1352-1362. PMID: 24120969.
      Citations: 11     Fields:    Translation:HumansCells
    133. Kwong LN, Davies MA. Navigating the therapeutic complexity of PI3K pathway inhibition in melanoma. Clin Cancer Res. 2013 Oct 01; 19(19):5310-9. PMID: 24089444.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    134. Prickett TD, Zerlanko B, Gartner JJ, Parker SCJ, Dutton-Regester K, Lin JC, Teer JK, Wei X, Jiang J, Chen G, Davies MA, Gershenwald JE, Robinson W, Robinson S, Hayward NK, Rosenberg SA, Margulies EH, Samuels Y. Somatic mutations in MAP3K5 attenuate its proapoptotic function in melanoma through increased binding to thioredoxin. J Invest Dermatol. 2014 Feb; 134(2):452-460. PMID: 24008424.
      Citations: 10     Fields:    Translation:HumansCells
    135. Bowles DW, Ma WW, Senzer N, Brahmer JR, Adjei AA, Davies M, Lazar AJ, Vo A, Peterson S, Walker L, Hausman D, Rudin CM, Jimeno A. A multicenter phase 1 study of PX-866 in combination with docetaxel in patients with advanced solid tumours. Br J Cancer. 2013 Sep 03; 109(5):1085-92. PMID: 23942080.
      Citations: 18     Fields:    Translation:HumansCTClinical Trials
    136. Bucheit AD, Syklawer E, Jakob JA, Bassett RL, Curry JL, Gershenwald JE, Kim KB, Hwu P, Lazar AJ, Davies MA. Clinical characteristics and outcomes with specific BRAF and NRAS mutations in patients with metastatic melanoma. Cancer. 2013 Nov 01; 119(21):3821-9. PMID: 23922205.
      Citations: 34     Fields:    Translation:Humans
    137. Gartner JJ, Parker SC, Prickett TD, Dutton-Regester K, Stitzel ML, Lin JC, Davis S, Simhadri VL, Jha S, Katagiri N, Gotea V, Teer JK, Wei X, Morken MA, Bhanot UK, Chen G, Elnitski LL, Davies MA, Gershenwald JE, Carter H, Karchin R, Robinson W, Robinson S, Rosenberg SA, Collins FS, Parmigiani G, Komar AA, Kimchi-Sarfaty C, Hayward NK, Margulies EH, Samuels Y. Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13481-6. PMID: 23901115.
      Citations: 78     Fields:    Translation:HumansCells
    138. Thorpe GW, Reodica M, Davies MJ, Heeren G, Jarolim S, Pillay B, Breitenbach M, Higgins VJ, Dawes IW. Superoxide radicals have a protective role during H2O2 stress. Mol Biol Cell. 2013 Sep; 24(18):2876-84. PMID: 23864711.
      Citations: 19     Fields:    Translation:AnimalsCells
    139. Nathanson KL, Martin AM, Wubbenhorst B, Greshock J, Letrero R, D'Andrea K, O'Day S, Infante JR, Falchook GS, Arkenau HT, Millward M, Brown MP, Pavlick A, Davies MA, Ma B, Gagnon R, Curtis M, Lebowitz PF, Kefford R, Long GV. Tumor genetic analyses of patients with metastatic melanoma treated with the BRAF inhibitor dabrafenib (GSK2118436). Clin Cancer Res. 2013 Sep 01; 19(17):4868-78. PMID: 23833299.
      Citations: 77     Fields:    Translation:HumansCTClinical Trials
    140. Overman MJ, Zhang J, Kopetz S, Davies M, Jiang ZQ, Zhi-Qin J, Stemke-Hale K, Rümmele P, Pilarsky C, Grützmann R, Hamilton S, Hwang R, Abbruzzese JL, Varadhachary G, Broom B, Wang H. Gene expression profiling of ampullary carcinomas classifies ampullary carcinomas into biliary-like and intestinal-like subtypes that are prognostic of outcome. PLoS One. 2013; 8(6):e65144. PMID: 23776447.
      Citations: 18     Fields:    Translation:Humans
    141. Brown BE, Nobecourt E, Zeng J, Jenkins AJ, Rye KA, Davies MJ. Apolipoprotein A-I glycation by glucose and reactive aldehydes alters phospholipid affinity but not cholesterol export from lipid-laden macrophages. PLoS One. 2013; 8(5):e65430. PMID: 23741493.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    142. Sun P, Tunceli K, Zhang Q, Seck T, Iglay K, Davies MJ, Ambegaonkar B, Radican L. Time to initiation of oral antihyperglycemic and statin therapy in previously untreated patients with type 2 diabetes in the United States. Curr Med Res Opin. 2013 Jul; 29(7):801-6. PMID: 23621515.
      Citations:    Fields:    Translation:Humans
    143. Whitrow MJ, Davies MJ, Giles LC, De Stavola BL, Owens JA, Maftei O, Moore VM. Effects of birth size, post-natal growth and current size on insulin resistance in 9-year-old children: a prospective cohort study. Eur J Pediatr. 2013 Sep; 172(9):1207-14. PMID: 23652936.
      Citations: 7     Fields:    Translation:Humans
    144. Gelbard A, Hale KS, Takahashi Y, Davies M, Kupferman ME, El-Naggar AK, Myers JN, Hanna EY. Molecular profiling of sinonasal undifferentiated carcinoma. Head Neck. 2014 Jan; 36(1):15-21. PMID: 23633104.
      Citations: 4     Fields:    Translation:Humans
    145. Charbonnel B, Steinberg H, Eymard E, Xu L, Thakkar P, Prabhu V, Davies MJ, Engel SS. Efficacy and safety over 26 weeks of an oral treatment strategy including sitagliptin compared with an injectable treatment strategy with liraglutide in patients with type 2 diabetes mellitus inadequately controlled on metformin: a randomised clinical trial. Diabetologia. 2013 Jul; 56(7):1503-11. PMID: 23604551.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    146. Wilmot EG, Edwardson CL, Biddle SJ, Gorely T, Henson J, Khunti K, Nimmo MA, Yates T, Davies MJ. Prevalence of diabetes and impaired glucose metabolism in younger 'at risk' UK adults: insights from the STAND programme of research. Diabet Med. 2013 Jun; 30(6):671-5. PMID: 23506383.
      Citations: 13     Fields:    Translation:Humans
    147. Makda SI, Davies MJ, Wilmot E, Bankart J, Yates T, Varghese EM, Fisher H, Anwar A, Khunti K. Prescribing in pregnancy for women with diabetes: use of potential teratogenic drugs and contraception. Diabet Med. 2013 Apr; 30(4):457-63. PMID: 23110381.
      Citations: 3     Fields:    Translation:Humans
    148. Henson J, Yates T, Biddle SJ, Edwardson CL, Khunti K, Wilmot EG, Gray LJ, Gorely T, Nimmo MA, Davies MJ. Associations of objectively measured sedentary behaviour and physical activity with markers of cardiometabolic health. Diabetologia. 2013 May; 56(5):1012-20. PMID: 23456209.
      Citations: 122     Fields:    Translation:Humans
    149. Kwong LN, Davies MA. Targeted therapy for melanoma: rational combinatorial approaches. Oncogene. 2014 Jan 02; 33(1):1-9. PMID: 23416974.
      Citations: 39     Fields:    Translation:HumansAnimals
    150. Atkinson CJ, Davies MJ, Taylor JM, Longbottom H. Linking ascorbic acid production in Ribes nigrum with fruit development and changes in sources and sinks. Ann Bot. 2013 Apr; 111(4):703-12. PMID: 23419248.
      Citations: 1     Fields:    Translation:Animals
    151. Arjona Ferreira JC, Corry D, Mogensen CE, Sloan L, Xu L, Golm GT, Gonzalez EJ, Davies MJ, Kaufman KD, Goldstein BJ. Efficacy and safety of sitagliptin in patients with type 2 diabetes and ESRD receiving dialysis: a 54-week randomized trial. Am J Kidney Dis. 2013 Apr; 61(4):579-87. PMID: 23352379.
      Citations: 42     Fields:    Translation:Humans
    152. Engel SS, Golm GT, Shapiro D, Davies MJ, Kaufman KD, Goldstein BJ. Cardiovascular safety of sitagliptin in patients with type 2 diabetes mellitus: a pooled analysis. Cardiovasc Diabetol. 2013 Jan 03; 12:3. PMID: 23286208.
      Citations: 32     Fields:    Translation:Humans
    153. Greaves WO, Verma S, Patel KP, Davies MA, Barkoh BA, Galbincea JM, Yao H, Lazar AJ, Aldape KD, Medeiros LJ, Luthra R. Frequency and spectrum of BRAF mutations in a retrospective, single-institution study of 1112 cases of melanoma. J Mol Diagn. 2013 Mar; 15(2):220-6. PMID: 23273605.
      Citations: 74     Fields:    Translation:HumansCells
    154. Mao M, Tian F, Mariadason JM, Tsao CC, Lemos R, Dayyani F, Gopal YN, Jiang ZQ, Wistuba II, Tang XM, Bornman WG, Bollag G, Mills GB, Powis G, Desai J, Gallick GE, Davies MA, Kopetz S. Resistance to BRAF inhibition in BRAF-mutant colon cancer can be overcome with PI3K inhibition or demethylating agents. Clin Cancer Res. 2013 Feb 01; 19(3):657-67. PMID: 23251002.
      Citations: 123     Fields:    Translation:HumansAnimalsCells
    155. Davies MA, Kopetz S. Overcoming resistance to MAPK pathway inhibitors. J Natl Cancer Inst. 2013 Jan 02; 105(1):9-10. PMID: 23250957.
      Citations: 3     Fields:    Translation:HumansAnimals
    156. Brodovicz KG, Mehta V, Zhang Q, Zhao C, Davies MJ, Chen J, Radican L, Engel SS. Association between hypoglycemia and inpatient mortality and length of hospital stay in hospitalized, insulin-treated patients. Curr Med Res Opin. 2013 Feb; 29(2):101-7. PMID: 23198978.
      Citations: 29     Fields:    Translation:Humans
    157. Liu C, Peng W, Xu C, Lou Y, Zhang M, Wargo JA, Chen JQ, Li HS, Watowich SS, Yang Y, Tompers Frederick D, Cooper ZA, Mbofung RM, Whittington M, Flaherty KT, Woodman SE, Davies MA, Radvanyi LG, Overwijk WW, Lizée G, Hwu P. BRAF inhibition increases tumor infiltration by T cells and enhances the antitumor activity of adoptive immunotherapy in mice. Clin Cancer Res. 2013 Jan 15; 19(2):393-403. PMID: 23204132.
      Citations: 153     Fields:    Translation:HumansAnimalsCells
    158. Joseph RW, Eckel-Passow JE, Sharma R, Liu P, Parker A, Jakob J, Buchbinder E, Bassett RL, Davies MA, Hwu P, Atkins MB, Sullivan RJ. Characterizing the clinical benefit of ipilimumab in patients who progressed on high-dose IL-2. J Immunother. 2012 Nov-Dec; 35(9):711-5. PMID: 23090080.
      Citations: 7     Fields:    Translation:Humans
    159. Simmons RK, Sharp SJ, Sandbæk A, Borch-Johnsen K, Davies MJ, Khunti K, Lauritzen T, Rutten GE, van den Donk M, Wareham NJ, Griffin SJ. Does early intensive multifactorial treatment reduce total cardiovascular burden in individuals with screen-detected diabetes? Findings from the ADDITION-Europe cluster-randomized trial. Diabet Med. 2012 Nov; 29(11):e409-16. PMID: 22823477.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    160. Long GV, Trefzer U, Davies MA, Kefford RF, Ascierto PA, Chapman PB, Puzanov I, Hauschild A, Robert C, Algazi A, Mortier L, Tawbi H, Wilhelm T, Zimmer L, Switzky J, Swann S, Martin AM, Guckert M, Goodman V, Streit M, Kirkwood JM, Schadendorf D. Dabrafenib in patients with Val600Glu or Val600Lys BRAF-mutant melanoma metastatic to the brain (BREAK-MB): a multicentre, open-label, phase 2 trial. Lancet Oncol. 2012 Nov; 13(11):1087-95. PMID: 23051966.
      Citations: 269     Fields:    Translation:HumansCTClinical Trials
    161. Radvanyi LG, Bernatchez C, Zhang M, Fox PS, Miller P, Chacon J, Wu R, Lizee G, Mahoney S, Alvarado G, Glass M, Johnson VE, McMannis JD, Shpall E, Prieto V, Papadopoulos N, Kim K, Homsi J, Bedikian A, Hwu WJ, Patel S, Ross MI, Lee JE, Gershenwald JE, Lucci A, Royal R, Cormier JN, Davies MA, Mansaray R, Fulbright OJ, Toth C, Ramachandran R, Wardell S, Gonzalez A, Hwu P. Specific lymphocyte subsets predict response to adoptive cell therapy using expanded autologous tumor-infiltrating lymphocytes in metastatic melanoma patients. Clin Cancer Res. 2012 Dec 15; 18(24):6758-70. PMID: 23032743.
      Citations: 154     Fields:    Translation:HumansCellsCTClinical Trials
    162. Gray LJ, Khunti K, Edwardson C, Goldby S, Henson J, Morris DH, Sheppard D, Webb D, Williams S, Yates T, Davies MJ. Implementation of the automated Leicester Practice Risk Score in two diabetes prevention trials provides a high yield of people with abnormal glucose tolerance. Diabetologia. 2012 Dec; 55(12):3238-44. PMID: 23001376.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    163. Patel SP, Lazar AJ, Papadopoulos NE, Liu P, Infante JR, Glass MR, Vaughn CS, LoRusso PM, Cohen RB, Davies MA, Kim KB. Clinical responses to selumetinib (AZD6244; ARRY-142886)-based combination therapy stratified by gene mutations in patients with metastatic melanoma. Cancer. 2013 Feb 15; 119(4):799-805. PMID: 22972589.
      Citations: 36     Fields:    Translation:HumansCTClinical Trials
    164. Speight J, Khagram LA, Davies MJ. Generic and diabetes-specific well-being in the AT.LANTUS Follow-on study: further psychometric validation of the W-BQ28 indicates its utility in research and clinical practice in Type 2 diabetes in the UK. Diabet Med. 2012 Sep; 29(9):e345-53. PMID: 22540936.
      Citations: 2     Fields:    Translation:Humans
    165. Alvarado G, Noor R, Bassett R, Papadopoulos NE, Kim KB, Hwu WJ, Bedikian A, Patel S, Hwu P, Davies MA. Risk of intracranial hemorrhage with anticoagulation therapy in melanoma patients with brain metastases. Melanoma Res. 2012 Aug; 22(4):310-5. PMID: 22584956.
      Citations: 17     Fields:    Translation:Humans
    166. Khalili JS, Liu S, Rodríguez-Cruz TG, Whittington M, Wardell S, Liu C, Zhang M, Cooper ZA, Frederick DT, Li Y, Zhang M, Joseph RW, Bernatchez C, Ekmekcioglu S, Grimm E, Radvanyi LG, Davis RE, Davies MA, Wargo JA, Hwu P, Lizée G. Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma. Clin Cancer Res. 2012 Oct 01; 18(19):5329-40. PMID: 22850568.
      Citations: 133     Fields:    Translation:HumansCells
    167. Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K, Wagle N, Wargo J, Chong K, Morton DL, Stemke-Hale K, Chen G, Noble M, Meyerson M, Ladbury JE, Davies MA, Gershenwald JE, Wagner SN, Hoon DS, Schadendorf D, Lander ES, Gabriel SB, Getz G, Garraway LA, Chin L. A landscape of driver mutations in melanoma. Cell. 2012 Jul 20; 150(2):251-63. PMID: 22817889.
      Citations: 1004     Fields:    Translation:HumansCells
    168. Kim J, Lazar AJ, Davies MA, Homsi J, Papadopoulos NE, Hwu WJ, Bedikian AY, Woodman SE, Patel SP, Hwu P, Kim KB. BRAF, NRAS and KIT sequencing analysis of spindle cell melanoma. J Cutan Pathol. 2012 Sep; 39(9):821-5. PMID: 22809251.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    169. Krobot KJ, Ferrante SA, Davies MJ, Seck T, Meininger GE, Williams-Herman D, Kaufman KD, Goldstein BJ. Lower risk of hypoglycemia with sitagliptin compared to glipizide when either is added to metformin therapy: a pre-specified analysis adjusting for the most recently measured HbA(1c) value. Curr Med Res Opin. 2012 Aug; 28(8):1281-7. PMID: 22697277.
      Citations: 4     Fields:    Translation:Humans
    170. Aravind SR, Ismail SB, Balamurugan R, Gupta JB, Wadhwa T, Loh SM, Suryawanshi S, Davies MJ, Girman CJ, Katzeff HL, Radican L, Engel SS, Wolthers T. Hypoglycemia in patients with type 2 diabetes from India and Malaysia treated with sitagliptin or a sulfonylurea during Ramadan: a randomized, pragmatic study. Curr Med Res Opin. 2012 Aug; 28(8):1289-96. PMID: 22738801.
      Citations: 20     Fields:    Translation:Humans
    171. Khalili JS, Yu X, Wang J, Hayes BC, Davies MA, Lizee G, Esmaeli B, Woodman SE. Combination small molecule MEK and PI3K inhibition enhances uveal melanoma cell death in a mutant GNAQ- and GNA11-dependent manner. Clin Cancer Res. 2012 Aug 15; 18(16):4345-55. PMID: 22733540.
      Citations: 59     Fields:    Translation:HumansCells
    172. Marrett E, Zhang Q, Kanitscheider C, Davies MJ, Radican L, Feinglos MN. Physician reasons for nonpharmacologic treatment of hyperglycemia in older patients newly diagnosed with type 2 diabetes mellitus. Diabetes Ther. 2012 Nov; 3(1):5. PMID: 22700283.
      Citations: 4     
    173. Moheimani F, Kim CH, Rahmanto AS, van Reyk DM, Davies MJ. Inhibition of lysosomal function in macrophages incubated with elevated glucose concentrations: a potential contributory factor in diabetes-associated atherosclerosis. Atherosclerosis. 2012 Jul; 223(1):144-51. PMID: 22658253.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    174. Han S, Iglay K, Davies MJ, Zhang Q, Radican L. Glycemic effectiveness and medication adherence with fixed-dose combination or coadministered dual therapy of antihyperglycemic regimens: a meta-analysis. Curr Med Res Opin. 2012 Jun; 28(6):969-77. PMID: 22494018.
      Citations: 12     Fields:    Translation:Humans
    175. Beasley GM, Coleman AP, Raymond A, Sanders G, Selim MA, Peterson BL, Brady MS, Davies MA, Augustine C, Tyler DS. A phase I multi-institutional study of systemic sorafenib in conjunction with regional melphalan for in-transit melanoma of the extremity. Ann Surg Oncol. 2012 Nov; 19(12):3896-3905. PMID: 22549288.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    176. Truscott RJ, Mizdrak J, Friedrich MG, Hooi MY, Lyons B, Jamie JF, Davies MJ, Wilmarth PA, David LL. Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine? Exp Eye Res. 2012 Jun; 99:48-54. PMID: 22542751.
      Citations: 9     Fields:    Translation:HumansCells
    177. Al-Zaid T, Ditelberg JS, Prieto VG, Lev D, Luthra R, Davies MA, Diwan AH, Wang WL, Lazar AJ. Trichilemmomas show loss of PTEN in Cowden syndrome but only rarely in sporadic tumors. J Cutan Pathol. 2012 May; 39(5):493-9. PMID: 22486434.
      Citations: 8     Fields:    Translation:Humans
    178. Mu H, Calderone TL, Davies MA, Prieto VG, Wang H, Mills GB, Bar-Eli M, Gershenwald JE. Lysophosphatidic acid induces lymphangiogenesis and IL-8 production in vitro in human lymphatic endothelial cells. Am J Pathol. 2012 May; 180(5):2170-81. PMID: 22465753.
      Citations: 13     Fields:    Translation:HumansCells
    179. Sinclair AJ, Alexander CM, Davies MJ, Zhao C, Mavros P. Factors associated with initiation of antihyperglycaemic medication in UK patients with newly diagnosed type 2 diabetes. BMC Endocr Disord. 2012 Mar 07; 12:1. PMID: 22397700.
      Citations: 6     Fields:    
    180. Davies MA. The role of the PI3K-AKT pathway in melanoma. Cancer J. 2012 Mar-Apr; 18(2):142-7. PMID: 22453015.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    181. Davies MA. Special issue on melanoma. Cancer J. 2012 Mar-Apr; 18(2):115-6. PMID: 22453010.
      Citations:    Fields:    Translation:HumansAnimals
    182. Davies MJ, Chubb BD, Smith IC, Valentine WJ. Cost-utility analysis of liraglutide compared with sulphonylurea or sitagliptin, all as add-on to metformin monotherapy in Type 2 diabetes mellitus. Diabet Med. 2012 Mar; 29(3):313-20. PMID: 21883438.
      Citations: 15     Fields:    Translation:Humans
    183. Woodman SE, Lazar AJ, Aldape KD, Davies MA. New strategies in melanoma: molecular testing in advanced disease. Clin Cancer Res. 2012 Mar 01; 18(5):1195-200. PMID: 22275506.
      Citations: 14     Fields:    Translation:HumansCells
    184. Deng W, Gopal YN, Scott A, Chen G, Woodman SE, Davies MA. Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition. Pigment Cell Melanoma Res. 2012 Mar; 25(2):248-58. PMID: 22171948.
      Citations: 53     Fields:    Translation:HumansCells
    185. Chattopadhyay C, Ellerhorst JA, Ekmekcioglu S, Greene VR, Davies MA, Grimm EA. Association of activated c-Met with NRAS-mutated human melanomas. Int J Cancer. 2012 Jul 15; 131(2):E56-65. PMID: 22020736.
      Citations: 25     Fields:    Translation:HumansCells
    186. Gray LJ, Davies MJ, Hiles S, Taub NA, Webb DR, Srinivasan BT, Khunti K. Detection of impaired glucose regulation and/or type 2 diabetes mellitus, using primary care electronic data, in a multiethnic UK community setting. Diabetologia. 2012 Apr; 55(4):959-66. PMID: 22231125.
      Citations: 20     Fields:    Translation:HumansPHPublic Health
    187. Davies MA, Fox PS, Papadopoulos NE, Bedikian AY, Hwu WJ, Lazar AJ, Prieto VG, Culotta KS, Madden TL, Xu Q, Huang S, Deng W, Ng CS, Gupta S, Liu W, Dancey JE, Wright JJ, Bassett RL, Hwu P, Kim KB. Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma. Clin Cancer Res. 2012 Feb 15; 18(4):1120-8. PMID: 22223528.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    188. Davies MA. Targeted therapy for brain metastases. Adv Pharmacol. 2012; 65:109-42. PMID: 22959025.
      Citations: 3     Fields:    Translation:HumansCells
    189. Joseph RW, Sullivan RJ, Harrell R, Stemke-Hale K, Panka D, Manoukian G, Percy A, Bassett RL, Ng CS, Radvanyi L, Hwu P, Atkins MB, Davies MA. Correlation of NRAS mutations with clinical response to high-dose IL-2 in patients with advanced melanoma. J Immunother. 2012 Jan; 35(1):66-72. PMID: 22130161.
      Citations: 50     Fields:    Translation:Humans
    190. Cook NL, Viola HM, Sharov VS, Hool LC, Schöneich C, Davies MJ. Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca2+-ATPase activity and perturb Ca2+ homeostasis in human coronary artery endothelial cells. Free Radic Biol Med. 2012 Mar 01; 52(5):951-61. PMID: 22214747.
      Citations: 13     Fields:    Translation:HumansCells
    191. Jakob JA, Bassett RL, Ng CS, Curry JL, Joseph RW, Alvarado GC, Rohlfs ML, Richard J, Gershenwald JE, Kim KB, Lazar AJ, Hwu P, Davies MA. NRAS mutation status is an independent prognostic factor in metastatic melanoma. Cancer. 2012 Aug 15; 118(16):4014-23. PMID: 22180178.
      Citations: 229     Fields:    Translation:Humans
    192. Bedikian AY, Wei C, Detry M, Kim KB, Papadopoulos NE, Hwu WJ, Homsi J, Davies M, McIntyre S, Hwu P. Predictive factors for the development of brain metastasis in advanced unresectable metastatic melanoma. Am J Clin Oncol. 2011 Dec; 34(6):603-10. PMID: 21150567.
      Citations: 16     Fields:    Translation:Humans
    193. Davies MJ, Wells C, Squires PA, Hodgetts TJ, Lecky FE. Civilian firearm injury and death in England and Wales. Emerg Med J. 2012 Jan; 29(1):10-4. PMID: 22058090.
      Citations: 6     Fields:    Translation:Humans
    194. Williams-Herman D, Xu L, Teng R, Golm GT, Johnson J, Davies MJ, Kaufman KD, Goldstein BJ. Effect of initial combination therapy with sitagliptin and metformin on ß-cell function in patients with type 2 diabetes. Diabetes Obes Metab. 2012 Jan; 14(1):67-76. PMID: 22050786.
      Citations: 14     Fields:    Translation:HumansCells
    195. Zhang Q, Zhao C, Davies MJ, Radican L, Seck T. Compliance and persistence with concomitant statin and oral antihyperglycemic therapy. Am J Manag Care. 2011 Nov; 17(11):746-52. PMID: 22084894.
      Citations: 6     Fields:    Translation:Humans
    196. van den Donk M, Sandbaek A, Borch-Johnsen K, Lauritzen T, Simmons RK, Wareham NJ, Griffin SJ, Davies MJ, Khunti K, Rutten GE. Screening for type 2 diabetes. Lessons from the ADDITION-Europe study. Diabet Med. 2011 Nov; 28(11):1416-24. PMID: 21679235.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    197. Zhang Q, Rajagopalan S, Marrett E, Davies MJ, Radican L, Engel SS. Time to treatment initiation with oral antihyperglycaemic therapy in US patients with newly diagnosed type 2 diabetes. Diabetes Obes Metab. 2012 Feb; 14(2):149-54. PMID: 21952003.
      Citations: 8     Fields:    Translation:Humans
    198. Zhang Q, Marrett E, Jameson K, Meiler S, Davies MJ, Radican L, Sinclair AJ. Reasons given by general practitioners for non-treatment decisions in younger and older patients with newly diagnosed type 2 diabetes mellitus in the United Kingdom: a survey study. BMC Endocr Disord. 2011 Oct 28; 11:17. PMID: 22035104.
      Citations: 3     Fields:    
    199. Davies MA. Regulation, role, and targeting of Akt in cancer. J Clin Oncol. 2011 Dec 10; 29(35):4715-7. PMID: 22025159.
      Citations: 20     Fields:    Translation:Humans
    200. Meininger GE, Scott R, Alba M, Shentu Y, Luo E, Amin H, Davies MJ, Kaufman KD, Goldstein BJ. Effects of MK-0941, a novel glucokinase activator, on glycemic control in insulin-treated patients with type 2 diabetes. Diabetes Care. 2011 Dec; 34(12):2560-6. PMID: 21994424.
      Citations: 56     Fields:    Translation:HumansCTClinical Trials
    201. Davies MJ, Marino JL, Willson KJ, March WA, Moore VM. Intergenerational associations of chronic disease and polycystic ovary syndrome. PLoS One. 2011; 6(10):e25947. PMID: 21991389.
      Citations: 6     Fields:    Translation:Humans
    202. Al Sifri S, Basiounny A, Echtay A, Al Omari M, Harman-Boehm I, Kaddaha G, Al Tayeb K, Mahfouz AS, Al Elq A, Radican L, Ozesen C, Katzeff HL, Musser BJ, Suryawanshi S, Girman CJ, Davies MJ, Engel SS. The incidence of hypoglycaemia in Muslim patients with type 2 diabetes treated with sitagliptin or a sulphonylurea during Ramadan: a randomised trial. Int J Clin Pract. 2011 Nov; 65(11):1132-40. PMID: 21951832.
      Citations: 38     Fields:    Translation:Humans
    203. Prickett TD, Wei X, Cardenas-Navia I, Teer JK, Lin JC, Walia V, Gartner J, Jiang J, Cherukuri PF, Molinolo A, Davies MA, Gershenwald JE, Stemke-Hale K, Rosenberg SA, Margulies EH, Samuels Y. Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma. Nat Genet. 2011 Sep 25; 43(11):1119-26. PMID: 21946352.
      Citations: 74     Fields:    Translation:Humans
    204. Chen G, Davies MA. Emerging insights into the molecular biology of brain metastases. Biochem Pharmacol. 2012 Feb 01; 83(3):305-14. PMID: 21946085.
      Citations: 12     Fields:    Translation:HumansAnimals
    205. Moheimani F, Tan JT, Brown BE, Heather AK, van Reyk DM, Davies MJ. Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins. Exp Diabetes Res. 2011; 2011:851280. PMID: 21904540.
      Citations: 5     Fields:    Translation:HumansCells
    206. Mehta RL, Davies MJ, Ali S, Taub NA, Stone MA, Baker R, McNally PG, Lawrence IG, Khunti K. Association of cardiac and non-cardiac chronic disease comorbidity on glycaemic control in a multi-ethnic population with type 1 and type 2 diabetes. Postgrad Med J. 2011 Nov; 87(1033):763-8. PMID: 21873464.
      Citations: 2     Fields:    Translation:Humans
    207. Hatiboglu MA, Kong LY, Wei J, Wang Y, McEnery KA, Fuller GN, Qiao W, Davies MA, Priebe W, Heimberger AB. The tumor microenvironment expression of p-STAT3 influences the efficacy of cyclophosphamide with WP1066 in murine melanoma models. Int J Cancer. 2012 Jul 01; 131(1):8-17. PMID: 21792892.
      Citations: 12     Fields:    Translation:AnimalsCells
    208. Marrett E, Radican L, Davies MJ, Zhang Q. Assessment of severity and frequency of self-reported hypoglycemia on quality of life in patients with type 2 diabetes treated with oral antihyperglycemic agents: A survey study. BMC Res Notes. 2011 Jul 21; 4:251. PMID: 21777428.
      Citations: 37     Fields:    
    209. Webb DR, Gray LJ, Khunti K, Srinivasan B, Taub N, Campbell S, Barnett J, Farooqi A, Echouffo-Tcheugui JB, Griffin SJ, Wareham NJ, Davies MJ. Screening for diabetes using an oral glucose tolerance test within a western multi-ethnic population identifies modifiable cardiovascular risk: the ADDITION-Leicester study. Diabetologia. 2011 Sep; 54(9):2237-46. PMID: 21638133.
      Citations: 20     Fields:    Translation:HumansPHPublic Health
    210. Crasto W, Jarvis J, Khunti K, Skinner TC, Gray LJ, Brela J, Troughton J, Daly H, Lawrence IG, McNally PG, Carey ME, Davies MJ. Multifactorial intervention in individuals with type 2 diabetes and microalbuminuria: the Microalbuminuria Education and Medication Optimisation (MEMO) study. Diabetes Res Clin Pract. 2011 Sep; 93(3):328-36. PMID: 21640424.
      Citations: 10     Fields:    Translation:Humans
    211. Aravind SR, Al Tayeb K, Ismail SB, Shehadeh N, Kaddaha G, Liu R, Balshaw R, Lesnikova N, Heisel O, Girman CJ, Musser BJ, Davies MJ, Katzeff HL, Engel SS, Radican L. Hypoglycaemia in sulphonylurea-treated subjects with type 2 diabetes undergoing Ramadan fasting: a five-country observational study. Curr Med Res Opin. 2011 Jun; 27(6):1237-42. PMID: 21506631.
      Citations: 28     Fields:    Translation:Humans
    212. Wei X, Walia V, Lin JC, Teer JK, Prickett TD, Gartner J, Davis S, Stemke-Hale K, Davies MA, Gershenwald JE, Robinson W, Robinson S, Rosenberg SA, Samuels Y. Exome sequencing identifies GRIN2A as frequently mutated in melanoma. Nat Genet. 2011 May; 43(5):442-6. PMID: 21499247.
      Citations: 251     Fields:    Translation:HumansCells
    213. Jilaveanu LB, Zito CR, Aziz SA, Chakraborty A, Davies MA, Camp RL, Rimm DL, Dudek A, Sznol M, Kluger HM. In vitro studies of dasatinib, its targets and predictors of sensitivity. Pigment Cell Melanoma Res. 2011 Apr; 24(2):386-9. PMID: 21320292.
      Citations: 9     Fields:    Translation:HumansCells
    214. Fu AZ, Zhang Q, Davies MJ, Pentakota SR, Radican L, Seck T. Underutilization of statins in patients with type 2 diabetes in US clinical practice: a retrospective cohort study. Curr Med Res Opin. 2011 May; 27(5):1035-40. PMID: 21410303.
      Citations: 5     Fields:    Translation:Humans
    215. Sourris KC, Harcourt BE, Penfold SA, Yap FY, Morley AL, Morgan PE, Davies MJ, Baker ST, Jerums G, Forbes JM. Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy. Exp Diabetes Res. 2010; 2010:974681. PMID: 21318189.
      Citations: 6     Fields:    Translation:Animals
    216. Davies MJ, Lee S, Lemke S, Ghabrial R. Predictors of anatomical patency following primary endonasal dacryocystorhinostomy: a pilot study. Orbit. 2011 Jan; 30(1):49-53. PMID: 21281082.
      Citations: 1     Fields:    Translation:Humans
    217. Davies MA, Gershenwald JE. Targeted therapy for melanoma: a primer. Surg Oncol Clin N Am. 2011 Jan; 20(1):165-80. PMID: 21111965.
      Citations: 9     Fields:    Translation:HumansCells
    218. Hennessy BT, Lu Y, Gonzalez-Angulo AM, Carey MS, Myhre S, Ju Z, Davies MA, Liu W, Coombes K, Meric-Bernstam F, Bedrosian I, McGahren M, Agarwal R, Zhang F, Overgaard J, Alsner J, Neve RM, Kuo WL, Gray JW, Borresen-Dale AL, Mills GB. A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers. Clin Proteomics. 2010 Dec; 6(4):129-51. PMID: 21691416.
      Citations: 119     
    219. Marino JL, Moore VM, Rumbold AR, Davies MJ. Fertility treatments and the young women who use them: an Australian cohort study. Hum Reprod. 2011 Feb; 26(2):473-9. PMID: 21071491.
      Citations: 3     Fields:    Translation:Humans
    220. Bedikian AY, Silverman JA, Papadopoulos NE, Kim KB, Hagey AE, Vardeleon A, Hwu WJ, Homsi J, Davies M, Hwu P. Pharmacokinetics and safety of Marqibo (vincristine sulfate liposomes injection) in cancer patients with impaired liver function. J Clin Pharmacol. 2011 Aug; 51(8):1205-12. PMID: 20978276.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    221. Gopal YN, Deng W, Woodman SE, Komurov K, Ram P, Smith PD, Davies MA. Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells. Cancer Res. 2010 Nov 01; 70(21):8736-47. PMID: 20959481.
      Citations: 132     Fields:    Translation:HumansCells
    222. Davies MA, Liu P, McIntyre S, Kim KB, Papadopoulos N, Hwu WJ, Hwu P, Bedikian A. Prognostic factors for survival in melanoma patients with brain metastases. Cancer. 2011 Apr 15; 117(8):1687-96. PMID: 20960525.
      Citations: 157     Fields:    Translation:Humans
    223. Wei X, Prickett TD, Viloria CG, Molinolo A, Lin JC, Cardenas-Navia I, Cruz P, Rosenberg SA, Davies MA, Gershenwald JE, López-Otín C, Samuels Y. Mutational and functional analysis reveals ADAMTS18 metalloproteinase as a novel driver in melanoma. Mol Cancer Res. 2010 Nov; 8(11):1513-25. PMID: 21047771.
      Citations: 22     Fields:    Translation:HumansCells
    224. Gillett M, Dallosso HM, Dixon S, Brennan A, Carey ME, Campbell MJ, Heller S, Khunti K, Skinner TC, Davies MJ. Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cost effectiveness analysis. BMJ. 2010 Aug 20; 341:c4093. PMID: 20729270.
      Citations: 61     Fields:    Translation:Humans
    225. Lane AE, Tan JT, Hawkins CL, Heather AK, Davies MJ. The myeloperoxidase-derived oxidant HOSCN inhibits protein tyrosine phosphatases and modulates cell signalling via the mitogen-activated protein kinase (MAPK) pathway in macrophages. Biochem J. 2010 Aug 15; 430(1):161-9. PMID: 20528774.
      Citations: 22     Fields:    Translation:AnimalsCells
    226. Davies MA, Samuels Y. Analysis of the genome to personalize therapy for melanoma. Oncogene. 2010 Oct 14; 29(41):5545-55. PMID: 20697348.
      Citations: 47     Fields:    Translation:HumansCells
    227. Khunti K, Srinivasan BT, Shutler S, Davies MJ. Effect of insulin glargine on glycaemic control and weight in obese and non-obese people with type 2 diabetes: data from the AT.LANTUS trial. Diabetes Obes Metab. 2010 Aug; 12(8):683-8. PMID: 20590745.
      Citations: 4     Fields:    Translation:Humans
    228. Skinner TC, Carey ME, Cradock S, Dallosso HM, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K, Oliver L. Depressive symptoms in the first year from diagnosis of Type 2 diabetes: results from the DESMOND trial. Diabet Med. 2010 Aug; 27(8):965-7. PMID: 20653757.
      Citations: 11     Fields:    Translation:Humans
    229. Zhang Q, Rajagopalan S, Mavros P, Engel SS, Davies MJ, Yin D, Radican L. Baseline characteristic differences between patients prescribed sitagliptin vs. other oral antihyperglycemic agents: analysis of a US electronic medical record database. Curr Med Res Opin. 2010 Jul; 26(7):1697-703. PMID: 20465367.
      Citations: 7     Fields:    Translation:Humans
    230. Giles LC, Glonek GF, Moore VM, Davies MJ, Luszcz MA. Lower age at menarche affects survival in older Australian women: results from the Australian Longitudinal Study of Ageing. BMC Public Health. 2010 Jun 15; 10:341. PMID: 20546623.
      Citations: 10     Fields:    Translation:Humans
    231. Altman MK, Gopal V, Jia W, Yu S, Hall H, Mills GB, McGinnis AC, Bartlett MG, Jiang G, Madan D, Prestwich GD, Xu Y, Davies MA, Murph MM. Targeting melanoma growth and viability reveals dualistic functionality of the phosphonothionate analogue of carba cyclic phosphatidic acid. Mol Cancer. 2010 Jun 09; 9:140. PMID: 20529378.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    232. Zhang Q, Rajagopalan S, Mavros P, Engel SS, Davies MJ, Yin D, Radican L. Differences in baseline characteristics between patients prescribed sitagliptin versus exenatide based on a US electronic medical record database. Adv Ther. 2010 Apr; 27(4):223-32. PMID: 20464538.
      Citations: 6     Fields:    Translation:Humans
    233. Woodman SE, Davies MA. Targeting KIT in melanoma: a paradigm of molecular medicine and targeted therapeutics. Biochem Pharmacol. 2010 Sep 01; 80(5):568-74. PMID: 20457136.
      Citations: 35     Fields:    Translation:Humans
    234. Williams-Herman D, Engel SS, Round E, Johnson J, Golm GT, Guo H, Musser BJ, Davies MJ, Kaufman KD, Goldstein BJ. Safety and tolerability of sitagliptin in clinical studies: a pooled analysis of data from 10,246 patients with type 2 diabetes. BMC Endocr Disord. 2010 Apr 22; 10:7. PMID: 20412573.
      Citations: 69     Fields:    
    235. Kennett EC, Rees MD, Malle E, Hammer A, Whitelock JM, Davies MJ. Peroxynitrite modifies the structure and function of the extracellular matrix proteoglycan perlecan by reaction with both the protein core and the heparan sulfate chains. Free Radic Biol Med. 2010 Jul 15; 49(2):282-93. PMID: 20416372.
      Citations: 7     Fields:    Translation:HumansCells
    236. Seck T, Nauck M, Sheng D, Sunga S, Davies MJ, Stein PP, Kaufman KD, Amatruda JM. Safety and efficacy of treatment with sitagliptin or glipizide in patients with type 2 diabetes inadequately controlled on metformin: a 2-year study. Int J Clin Pract. 2010 Apr; 64(5):562-76. PMID: 20456211.
      Citations: 57     Fields:    Translation:HumansCells
    237. Ding Z, Liang J, Li J, Lu Y, Ariyaratna V, Lu Z, Davies MA, Westwick JK, Mills GB. Physical association of PDK1 with AKT1 is sufficient for pathway activation independent of membrane localization and phosphatidylinositol 3 kinase. PLoS One. 2010 Mar 26; 5(3):e9910. PMID: 20361045.
      Citations: 22     Fields:    Translation:HumansCells
    238. Skinner TC, Carey ME, Cradock S, Dallosso HM, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K, Oliver L. Comparison of illness representations dimensions and illness representation clusters in predicting outcomes in the first year following diagnosis of type 2 diabetes: results from the DESMOND trial. Psychol Health. 2011 Mar; 26(3):321-35. PMID: 20309775.
      Citations: 7     Fields:    Translation:Humans
    239. Sikora AG, Gelbard A, Davies MA, Sano D, Ekmekcioglu S, Kwon J, Hailemichael Y, Jayaraman P, Myers JN, Grimm EA, Overwijk WW. Targeted inhibition of inducible nitric oxide synthase inhibits growth of human melanoma in vivo and synergizes with chemotherapy. Clin Cancer Res. 2010 Mar 15; 16(6):1834-44. PMID: 20215556.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    240. Webb DR, Khunti K, Silverman R, Gray LJ, Srinivasan B, Lacy PS, Williams B, Davies MJ. Impact of metabolic indices on central artery stiffness: independent association of insulin resistance and glucose with aortic pulse wave velocity. Diabetologia. 2010 Jun; 53(6):1190-8. PMID: 20213236.
      Citations: 38     Fields:    Translation:Humans
    241. Webb DR, Khunti K, Srinivasan B, Gray LJ, Taub N, Campbell S, Barnett J, Henson J, Hiles S, Farooqi A, Griffin SJ, Wareham NJ, Davies MJ. Rationale and design of the ADDITION-Leicester study, a systematic screening programme and randomised controlled trial of multi-factorial cardiovascular risk intervention in people with type 2 diabetes mellitus detected by screening. Trials. 2010 Feb 19; 11:16. PMID: 20170482.
      Citations: 28     Fields:    Translation:HumansPHPublic Health
    242. Park ES, Rabinovsky R, Carey M, Hennessy BT, Agarwal R, Liu W, Ju Z, Deng W, Lu Y, Woo HG, Kim SB, Cheong JH, Garraway LA, Weinstein JN, Mills GB, Lee JS, Davies MA. Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set. Mol Cancer Ther. 2010 Feb; 9(2):257-67. PMID: 20124458.
      Citations: 47     Fields:    Translation:HumansCells
    243. Nobécourt E, Tabet F, Lambert G, Puranik R, Bao S, Yan L, Davies MJ, Brown BE, Jenkins AJ, Dusting GJ, Bonnet DJ, Curtiss LK, Barter PJ, Rye KA. Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I. Arterioscler Thromb Vasc Biol. 2010 Apr; 30(4):766-72. PMID: 20110571.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    244. Koelsch M, Mallak R, Graham GG, Kajer T, Milligan MK, Nguyen LQ, Newsham DW, Keh JS, Kettle AJ, Scott KF, Ziegler JB, Pattison DI, Fu S, Hawkins CL, Rees MD, Davies MJ. Acetaminophen (paracetamol) inhibits myeloperoxidase-catalyzed oxidant production and biological damage at therapeutically achievable concentrations. Biochem Pharmacol. 2010 Apr 15; 79(8):1156-64. PMID: 19968966.
      Citations: 15     Fields:    Translation:HumansCells
    245. March WA, Moore VM, Willson KJ, Phillips DI, Norman RJ, Davies MJ. The prevalence of polycystic ovary syndrome in a community sample assessed under contrasting diagnostic criteria. Hum Reprod. 2010 Feb; 25(2):544-51. PMID: 19910321.
      Citations: 365     Fields:    Translation:Humans
    246. Whitrow MJ, Moore VM, Rumbold AR, Davies MJ. Effect of supplemental folic acid in pregnancy on childhood asthma: a prospective birth cohort study. Am J Epidemiol. 2009 Dec 15; 170(12):1486-93. PMID: 19880541.
      Citations: 93     Fields:    Translation:Humans
    247. Rees MD, Whitelock JM, Malle E, Chuang CY, Iozzo RV, Nilasaroya A, Davies MJ. Myeloperoxidase-derived oxidants selectively disrupt the protein core of the heparan sulfate proteoglycan perlecan. Matrix Biol. 2010 Jan; 29(1):63-73. PMID: 19788922.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    248. Jarvis J, Skinner TC, Carey ME, Davies MJ. How can structured self-management patient education improve outcomes in people with type 2 diabetes? Diabetes Obes Metab. 2010 Jan; 12(1):12-9. PMID: 19788430.
      Citations: 27     Fields:    Translation:Humans
    249. Torres-Cabala CA, Wang WL, Trent J, Yang D, Chen S, Galbincea J, Kim KB, Woodman S, Davies M, Plaza JA, Nash JW, Prieto VG, Lazar AJ, Ivan D. Correlation between KIT expression and KIT mutation in melanoma: a study of 173 cases with emphasis on the acral-lentiginous/mucosal type. Mod Pathol. 2009 Nov; 22(11):1446-56. PMID: 19718013.
      Citations: 45     Fields:    Translation:Humans
    250. Woodman SE, Trent JC, Stemke-Hale K, Lazar AJ, Pricl S, Pavan GM, Fermeglia M, Gopal YN, Yang D, Podoloff DA, Ivan D, Kim KB, Papadopoulos N, Hwu P, Mills GB, Davies MA. Activity of dasatinib against L576P KIT mutant melanoma: molecular, cellular, and clinical correlates. Mol Cancer Ther. 2009 Aug; 8(8):2079-85. PMID: 19671763.
      Citations: 65     Fields:    Translation:HumansCells
    251. Vasudevan KM, Barbie DA, Davies MA, Rabinovsky R, McNear CJ, Kim JJ, Hennessy BT, Tseng H, Pochanard P, Kim SY, Dunn IF, Schinzel AC, Sandy P, Hoersch S, Sheng Q, Gupta PB, Boehm JS, Reiling JH, Silver S, Lu Y, Stemke-Hale K, Dutta B, Joy C, Sahin AA, Gonzalez-Angulo AM, Lluch A, Rameh LE, Jacks T, Root DE, Lander ES, Mills GB, Hahn WC, Sellers WR, Garraway LA. AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer. Cancer Cell. 2009 Jul 07; 16(1):21-32. PMID: 19573809.
      Citations: 240     Fields:    Translation:HumansCells
    252. Kennett EC, Davies MJ. Glycosaminoglycans are fragmented by hydroxyl, carbonate, and nitrogen dioxide radicals in a site-selective manner: implications for peroxynitrite-mediated damage at sites of inflammation. Free Radic Biol Med. 2009 Aug 15; 47(4):389-400. PMID: 19427378.
      Citations: 8     Fields:    Translation:HumansCells
    253. Aziz SA, Davies M, Pick E, Zito C, Jilaveanu L, Camp RL, Rimm DL, Kluger Y, Kluger HM. Phosphatidylinositol-3-kinase as a therapeutic target in melanoma. Clin Cancer Res. 2009 May 01; 15(9):3029-36. PMID: 19383818.
      Citations: 29     Fields:    Translation:HumansCells
    254. Gracanin M, Hawkins CL, Pattison DI, Davies MJ. Singlet-oxygen-mediated amino acid and protein oxidation: formation of tryptophan peroxides and decomposition products. Free Radic Biol Med. 2009 Jul 01; 47(1):92-102. PMID: 19375501.
      Citations: 35     Fields:    Translation:AnimalsCells
    255. O'Reilly KE, Warycha M, Davies MA, Rodrik V, Zhou XK, Yee H, Polsky D, Pavlick AC, Rosen N, Bhardwaj N, Mills G, Osman I. Phosphorylated 4E-BP1 is associated with poor survival in melanoma. Clin Cancer Res. 2009 Apr 15; 15(8):2872-8. PMID: 19336517.
      Citations: 26     Fields:    Translation:HumansCells
    256. Williams-Herman D, Johnson J, Teng R, Luo E, Davies MJ, Kaufman KD, Goldstein BJ, Amatruda JM. Efficacy and safety of initial combination therapy with sitagliptin and metformin in patients with type 2 diabetes: a 54-week study. Curr Med Res Opin. 2009 Mar; 25(3):569-83. PMID: 19232032.
      Citations: 41     Fields:    Translation:Humans
    257. Morgan PE, Sturgess AD, Davies MJ. Evidence for chronically elevated serum protein oxidation in systemic lupus erythematosus patients. Free Radic Res. 2009 Feb; 43(2):117-27. PMID: 19096973.
      Citations: 15     Fields:    Translation:HumansCells
    258. Khunti K, Skinner TC, Heller S, Carey ME, Dallosso HM, Davies MJ. Biomedical, lifestyle and psychosocial characteristics of people newly diagnosed with Type 2 diabetes: baseline data from the DESMOND randomized controlled trial. Diabet Med. 2008 Dec; 25(12):1454-61. PMID: 19046245.
      Citations: 9     Fields:    Translation:Humans
    259. Baker AR, Harte AL, Howell N, Pritlove DC, Ranasinghe AM, da Silva NF, Youssef EM, Khunti K, Davies MJ, Bonser RS, Kumar S, Pagano D, McTernan PG. Epicardial adipose tissue as a source of nuclear factor-kappaB and c-Jun N-terminal kinase mediated inflammation in patients with coronary artery disease. J Clin Endocrinol Metab. 2009 Jan; 94(1):261-7. PMID: 18984670.
      Citations: 39     Fields:    Translation:HumansCells
    260. Lam MA, Pattison DI, Bottle SE, Keddie DJ, Davies MJ. Nitric oxide and nitroxides can act as efficient scavengers of protein-derived free radicals. Chem Res Toxicol. 2008 Nov; 21(11):2111-9. PMID: 18834151.
      Citations: 13     Fields:    Translation:Cells
    261. Williams-Herman D, Round E, Swern AS, Musser B, Davies MJ, Stein PP, Kaufman KD, Amatruda JM. Safety and tolerability of sitagliptin in patients with type 2 diabetes: a pooled analysis. BMC Endocr Disord. 2008 Oct 27; 8:14. PMID: 18954434.
      Citations: 31     Fields:    
    262. Davies MA, Stemke-Hale K, Tellez C, Calderone TL, Deng W, Prieto VG, Lazar AJ, Gershenwald JE, Mills GB. A novel AKT3 mutation in melanoma tumours and cell lines. Br J Cancer. 2008 Oct 21; 99(8):1265-8. PMID: 18813315.
      Citations: 110     Fields:    Translation:HumansCells
    263. Skinner TC, Carey ME, Cradock S, Dallosso HM, Daly H, Davies MJ, Doherty Y, Heller S, Khunti K, Oliver L. 'Educator talk' and patient change: some insights from the DESMOND (Diabetes Education and Self Management for Ongoing and Newly Diagnosed) randomized controlled trial. Diabet Med. 2008 Sep; 25(9):1117-20. PMID: 19183318.
      Citations: 19     Fields:    Translation:Humans
    264. Lloyd MM, van Reyk DM, Davies MJ, Hawkins CL. Hypothiocyanous acid is a more potent inducer of apoptosis and protein thiol depletion in murine macrophage cells than hypochlorous acid or hypobromous acid. Biochem J. 2008 Sep 01; 414(2):271-80. PMID: 18459943.
      Citations: 21     Fields:    Translation:AnimalsCells
    265. Khunti K, Camosso-Stefinovic J, Carey M, Davies MJ, Stone MA. Educational interventions for migrant South Asians with Type 2 diabetes: a systematic review. Diabet Med. 2008 Aug; 25(8):985-92. PMID: 18959614.
      Citations: 14     Fields:    Translation:Humans
    266. Stemke-Hale K, Gonzalez-Angulo AM, Lluch A, Neve RM, Kuo WL, Davies M, Carey M, Hu Z, Guan Y, Sahin A, Symmans WF, Pusztai L, Nolden LK, Horlings H, Berns K, Hung MC, van de Vijver MJ, Valero V, Gray JW, Bernards R, Mills GB, Hennessy BT. An integrative genomic and proteomic analysis of PIK3CA, PTEN, and AKT mutations in breast cancer. Cancer Res. 2008 Aug 01; 68(15):6084-91. PMID: 18676830.
      Citations: 467     Fields:    Translation:Humans
    267. Davies MJ, Hawkins CL, Pattison DI, Rees MD. Mammalian heme peroxidases: from molecular mechanisms to health implications. Antioxid Redox Signal. 2008 Jul; 10(7):1199-234. PMID: 18331199.
      Citations: 133     Fields:    Translation:HumansAnimals
    268. Xu L, Man CD, Charbonnel B, Meninger G, Davies MJ, Williams-Herman D, Cobelli C, Stein PP. Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on beta-cell function in patients with type 2 diabetes: a model-based approach. Diabetes Obes Metab. 2008 Dec; 10(12):1212-20. PMID: 18476982.
      Citations: 22     Fields:    Translation:HumansCells
    269. Nobécourt E, Zeng J, Davies MJ, Brown BE, Yadav S, Barter PJ, Rye KA. Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I. Diabetologia. 2008 Jun; 51(6):1008-17. PMID: 18437350.
      Citations: 11     Fields:    Translation:HumansCells
    270. Rees MD, Kennett EC, Whitelock JM, Davies MJ. Oxidative damage to extracellular matrix and its role in human pathologies. Free Radic Biol Med. 2008 Jun 15; 44(12):1973-2001. PMID: 18423414.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    271. Mistry GC, Maes AL, Lasseter KC, Davies MJ, Gottesdiener KM, Wagner JA, Herman GA. Effect of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on blood pressure in nondiabetic patients with mild to moderate hypertension. J Clin Pharmacol. 2008 May; 48(5):592-8. PMID: 18353996.
      Citations: 68     Fields:    Translation:Humans
    272. O'Brien PM, Davies MJ, Scurry JP, Smith AN, Barton CA, Henderson MJ, Saunders DN, Gloss BS, Patterson KI, Clancy JL, Heinzelmann-Schwarz VA, Murali R, Scolyer RA, Zeng Y, Williams ED, Scurr L, Defazio A, Quinn DI, Watts CK, Hacker NF, Henshall SM, Sutherland RL. The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro. Br J Cancer. 2008 Mar 25; 98(6):1085-93. PMID: 18349819.
      Citations: 27     Fields:    Translation:HumansCells
    273. Stadler N, Stanley N, Heeneman S, Vacata V, Daemen MJ, Bannon PG, Waltenberger J, Davies MJ. Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation. Arterioscler Thromb Vasc Biol. 2008 May; 28(5):1024-30. PMID: 18309112.
      Citations: 11     Fields:    Translation:HumansCells
    274. Davies MJ, Heller S, Skinner TC, Campbell MJ, Carey ME, Cradock S, Dallosso HM, Daly H, Doherty Y, Eaton S, Fox C, Oliver L, Rantell K, Rayman G, Khunti K. Effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes: cluster randomised controlled trial. BMJ. 2008 Mar 01; 336(7642):491-5. PMID: 18276664.
      Citations: 210     Fields:    Translation:Humans
    275. Karasik A, Aschner P, Katzeff H, Davies MJ, Stein PP. Sitagliptin, a DPP-4 inhibitor for the treatment of patients with type 2 diabetes: a review of recent clinical trials. Curr Med Res Opin. 2008 Feb; 24(2):489-96. PMID: 18182122.
      Citations: 41     Fields:    Translation:HumansCells
    276. Nonaka K, Kakikawa T, Sato A, Okuyama K, Fujimoto G, Kato N, Suzuki H, Hirayama Y, Ahmed T, Davies MJ, Stein PP. Efficacy and safety of sitagliptin monotherapy in Japanese patients with type 2 diabetes. Diabetes Res Clin Pract. 2008 Feb; 79(2):291-8. PMID: 17933414.
      Citations: 82     Fields:    Translation:Humans
    277. Dabadghao P, Roberts BJ, Wang J, Davies MJ, Norman RJ. Glucose tolerance abnormalities in Australian women with polycystic ovary syndrome. Med J Aust. 2007 Sep 17; 187(6):328-31. PMID: 17874978.
      Citations: 2     Fields:    Translation:Humans
    278. Parker NR, Korlimbinis A, Jamie JF, Davies MJ, Truscott RJ. Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses. Invest Ophthalmol Vis Sci. 2007 Aug; 48(8):3705-13. PMID: 17652742.
      Citations: 5     Fields:    Translation:AnimalsCells
    279. Cameron CM, Scott DA, McDonald WM, Davies MJ. A review of neuraxial epidural morbidity: experience of more than 8,000 cases at a single teaching hospital. Anesthesiology. 2007 May; 106(5):997-1002. PMID: 17457132.
      Citations: 24     Fields:    Translation:Humans
    280. Davies MJ, Thaware PK, Tringham JR, Howe J, Jarvis J, Johnston V, Kitchener DL, Skinner TC, McNally PG, Lawrence IG. A randomized controlled trial examining combinations of repaglinide, metformin and NPH insulin. Diabet Med. 2007 Jul; 24(7):714-9. PMID: 17403126.
      Citations: 5     Fields:    Translation:Humans
    281. Brown BE, Rashid I, van Reyk DM, Davies MJ. Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages. FEBS J. 2007 Mar; 274(6):1530-41. PMID: 17480204.
      Citations: 7     Fields:    Translation:HumansCells
    282. Gracanin M, Davies MJ. Inhibition of protein tyrosine phosphatases by amino acid, peptide, and protein hydroperoxides: potential modulation of cell signaling by protein oxidation products. Free Radic Biol Med. 2007 May 15; 42(10):1543-51. PMID: 17448901.
      Citations: 6     Fields:    Translation:AnimalsCells
    283. Rashid I, van Reyk DM, Davies MJ. Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro. FEBS Lett. 2007 Mar 06; 581(5):1067-70. PMID: 17316626.
      Citations: 15     Fields:    Translation:HumansCells
    284. Mistry GC, Bergman AJ, Luo WL, Cilissen C, Haazen W, Davies MJ, Gottesdiener KM, Wagner JA, Herman GA. Multiple-dose administration of sitagliptin, a dipeptidyl peptidase-4 inhibitor, does not alter the single-dose pharmacokinetics of rosiglitazone in healthy subjects. J Clin Pharmacol. 2007 Feb; 47(2):159-64. PMID: 17244766.
      Citations: 10     Fields:    Translation:Humans
    285. Chatterjee S, Jarvis-Kay J, Rengarajan T, Lawrence IG, McNally PG, Davies MJ. Glargine versus NPH insulin: efficacy in comparison with insulin aspart in a basal bolus regimen in type 1 diabetes--the glargine and aspart study (GLASS) a randomised cross-over study. Diabetes Res Clin Pract. 2007 Aug; 77(2):215-22. PMID: 17141354.
      Citations: 13     Fields:    Translation:Humans
    286. Davies M, Hennessy B, Mills GB. Point mutations of protein kinases and individualised cancer therapy. Expert Opin Pharmacother. 2006 Nov; 7(16):2243-61. PMID: 17059381.
      Citations: 9     Fields:    Translation:Humans
    287. Herman GA, Bergman A, Stevens C, Kotey P, Yi B, Zhao P, Dietrich B, Golor G, Schrodter A, Keymeulen B, Lasseter KC, Kipnes MS, Snyder K, Hilliard D, Tanen M, Cilissen C, De Smet M, de Lepeleire I, Van Dyck K, Wang AQ, Zeng W, Davies MJ, Tanaka W, Holst JJ, Deacon CF, Gottesdiener KM, Wagner JA. Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes. J Clin Endocrinol Metab. 2006 Nov; 91(11):4612-9. PMID: 16912128.
      Citations: 128     Fields:    Translation:Humans
    288. Davies MJ, Fisher LH, Chegini S, Craig TJ. A practical approach to allergic rhinitis and sleep disturbance management. Allergy Asthma Proc. 2006 May-Jun; 27(3):224-30. PMID: 16913265.
      Citations: 3     Fields:    Translation:Humans
    289. Ose L, Shah A, Davies MJ, Rotonda J, Maccubbin D, Tribble D, Veltri E, Mitchel Y. Consistency of lipid-altering effects of ezetimibe/simvastatin across gender, race, age, baseline low density lipoprotein cholesterol levels, and coronary heart disease status: results of a pooled retrospective analysis. Curr Med Res Opin. 2006 May; 22(5):823-35. PMID: 16709304.
      Citations:    Fields:    Translation:Humans
    290. Malle E, Marsche G, Arnhold J, Davies MJ. Modification of low-density lipoprotein by myeloperoxidase-derived oxidants and reagent hypochlorous acid. Biochim Biophys Acta. 2006 Apr; 1761(4):392-415. PMID: 16698314.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    291. Stanley N, Stadler N, Woods AA, Bannon PG, Davies MJ. Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions. Free Radic Biol Med. 2006 May 01; 40(9):1636-43. PMID: 16632123.
      Citations: 6     Fields:    Translation:HumansCells
    292. Decochez K, Rippley RK, Miller JL, De Smet M, Yan KX, Matthijs Z, Riffel KA, Song H, Zhu H, Maynor HO, Tanaka W, Johnson-Levonas AO, Davies MJ, Gottesdiener KM, Keymeulen B, Wagner JA. A dual PPAR alpha/gamma agonist increases adiponectin and improves plasma lipid profiles in healthy subjects. Drugs R D. 2006; 7(2):99-110. PMID: 16542056.
      Citations: 3     Fields:    Translation:Humans
    293. Herman GA, Stevens C, Van Dyck K, Bergman A, Yi B, De Smet M, Snyder K, Hilliard D, Tanen M, Tanaka W, Wang AQ, Zeng W, Musson D, Winchell G, Davies MJ, Ramael S, Gottesdiener KM, Wagner JA. Pharmacokinetics and pharmacodynamics of sitagliptin, an inhibitor of dipeptidyl peptidase IV, in healthy subjects: results from two randomized, double-blind, placebo-controlled studies with single oral doses. Clin Pharmacol Ther. 2005 Dec; 78(6):675-88. PMID: 16338283.
      Citations: 111     Fields:    Translation:Humans
    294. Camidge DR, Davies MJ, Laud PJ, Marshall AL, Cockerill M, Smith PD, Hughes AM. Factors determining the optimal body site and method for obtaining punch biopsies of human skin as a tissue in which to assess pharmacodynamic and pharmacokinetic endpoints in drug development studies. Cancer Chemother Pharmacol. 2006 Jan; 57(1):52-8. PMID: 16032432.
      Citations: 1     Fields:    Translation:HumansCells
    295. Davies MJ, Fisher LH, Chegini S, Craig TJ. Asthma and the diver. Clin Rev Allergy Immunol. 2005 Oct; 29(2):131-8. PMID: 16251767.
      Citations: 2     Fields:    Translation:Humans
    296. Fisher LH, Davies MJ, Craig TJ. Nasal obstruction, the airway, and the athlete. Clin Rev Allergy Immunol. 2005 Oct; 29(2):151-8. PMID: 16251769.
      Citations: 1     Fields:    
    297. Birinyi-Strachan LC, Davies MJ, Lewis RJ, Nicholson GM. Neuroprotectant effects of iso-osmolar D-mannitol to prevent Pacific ciguatoxin-1 induced alterations in neuronal excitability: a comparison with other osmotic agents and free radical scavengers. Neuropharmacology. 2005 Oct; 49(5):669-86. PMID: 15950247.
      Citations: 7     Fields:    Translation:Cells
    298. Hawkins CL, Davies MJ. Inactivation of protease inhibitors and lysozyme by hypochlorous acid: role of side-chain oxidation and protein unfolding in loss of biological function. Chem Res Toxicol. 2005 Oct; 18(10):1600-10. PMID: 16533025.
      Citations: 14     Fields:    Translation:AnimalsCells
    299. McKenney J, Ballantyne CM, Feldman TA, Brady WE, Shah A, Davies MJ, Palmisano J, Mitchel YB. LDL-C goal attainment with ezetimibe plus simvastatin coadministration vs atorvastatin or simvastatin monotherapy in patients at high risk of CHD. MedGenMed. 2005 Jul 14; 7(3):3. PMID: 16369229.
      Citations: 3     Fields:    Translation:Humans
    300. Farnier M, Volpe M, Massaad R, Davies MJ, Allen C. Effect of co-administering ezetimibe with on-going simvastatin treatment on LDL-C goal attainment in hypercholesterolemic patients with coronary heart disease. Int J Cardiol. 2005 Jul 10; 102(2):327-32. PMID: 15982505.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    301. Morgan PE, Sturgess AD, Davies MJ. Increased levels of serum protein oxidation and correlation with disease activity in systemic lupus erythematosus. Arthritis Rheum. 2005 Jul; 52(7):2069-79. PMID: 15986354.
      Citations: 41     Fields:    Translation:HumansCells
    302. Brohet C, Banai S, Alings AM, Massaad R, Davies MJ, Allen C. LDL-C goal attainment with the addition of ezetimibe to ongoing simvastatin treatment in coronary heart disease patients with hypercholesterolemia. Curr Med Res Opin. 2005 Apr; 21(4):571-8. PMID: 15899106.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    303. Palsson OS, Morteau O, Bozymski EM, Woosley JT, Sartor RB, Davies MJ, Johnson DA, Turner MJ, Whitehead WE. Elevated vasoactive intestinal peptide concentrations in patients with irritable bowel syndrome. Dig Dis Sci. 2004 Aug; 49(7-8):1236-43. PMID: 15387352.
      Citations: 13     Fields:    Translation:Humans
    304. Pyörälä K, Ballantyne CM, Gumbiner B, Lee MW, Shah A, Davies MJ, Mitchel YB, Pedersen TR, Kjekshus J. Reduction of cardiovascular events by simvastatin in nondiabetic coronary heart disease patients with and without the metabolic syndrome: subgroup analyses of the Scandinavian Simvastatin Survival Study (4S). Diabetes Care. 2004 Jul; 27(7):1735-40. PMID: 15220255.
      Citations: 29     Fields:    Translation:HumansCTClinical Trials
    305. Heinzelmann-Schwarz VA, Gardiner-Garden M, Henshall SM, Scurry J, Scolyer RA, Davies MJ, Heinzelmann M, Kalish LH, Bali A, Kench JG, Edwards LS, Vanden Bergh PM, Hacker NF, Sutherland RL, O'Brien PM. Overexpression of the cell adhesion molecules DDR1, Claudin 3, and Ep-CAM in metaplastic ovarian epithelium and ovarian cancer. Clin Cancer Res. 2004 Jul 01; 10(13):4427-36. PMID: 15240533.
      Citations: 79     Fields:    Translation:HumansCells
    306. Winterbourn CC, Parsons-Mair HN, Gebicki S, Gebicki JM, Davies MJ. Requirements for superoxide-dependent tyrosine hydroperoxide formation in peptides. Biochem J. 2004 Jul 01; 381(Pt 1):241-8. PMID: 15025556.
      Citations: 32     Fields:    Translation:Cells
    307. Wang JX, Warnes GW, Davies MJ, Norman RJ. Overweight infertile patients have a higher fecundity than normal-weight women undergoing controlled ovarian hyperstimulation with intrauterine insemination. Fertil Steril. 2004 Jun; 81(6):1710-2. PMID: 15193505.
      Citations: 7     Fields:    Translation:Humans
    308. Quraishi SA, Davies MJ, Craig TJ. Inflammatory responses in allergic rhinitis: traditional approaches and novel treatment strategies. J Am Osteopath Assoc. 2004 May; 104(5 Suppl 5):S7-15. PMID: 15176523.
      Citations: 9     Fields:    Translation:Humans
    309. Norman RJ, Noakes M, Wu R, Davies MJ, Moran L, Wang JX. Improving reproductive performance in overweight/obese women with effective weight management. Hum Reprod Update. 2004 May-Jun; 10(3):267-80. PMID: 15140873.
      Citations: 53     Fields:    Translation:Humans
    310. Pattison DI, Davies MJ. Kinetic analysis of the reactions of hypobromous acid with protein components: implications for cellular damage and use of 3-bromotyrosine as a marker of oxidative stress. Biochemistry. 2004 Apr 27; 43(16):4799-809. PMID: 15096049.
      Citations: 29     Fields:    Translation:HumansCells
    311. Davies MJ, Wang JX, Norman RJ. What is the most relevant standard of success in assisted reproduction? Assessing the BESST index for reproduction treatment. Hum Reprod. 2004 May; 19(5):1049-51. PMID: 15044408.
      Citations: 1     Fields:    Translation:Humans
    312. Stadler N, Lindner RA, Davies MJ. Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper. Arterioscler Thromb Vasc Biol. 2004 May; 24(5):949-54. PMID: 15001454.
      Citations: 71     Fields:    Translation:Humans
    313. Wang JX, Kwan M, Davies MJ, Kirby C, Judd S, Norman RJ. Risk of multiple pregnancy when infertility is treated with ovulation induction by gonadotropins. Fertil Steril. 2003 Sep; 80(3):664-5. PMID: 12969723.
      Citations:    Fields:    Translation:Humans
    314. Clancy JL, Henderson MJ, Russell AJ, Anderson DW, Bova RJ, Campbell IG, Choong DY, Macdonald GA, Mann GJ, Nolan T, Brady G, Olopade OI, Woollatt E, Davies MJ, Segara D, Hacker NF, Henshall SM, Sutherland RL, Watts CK. EDD, the human orthologue of the hyperplastic discs tumour suppressor gene, is amplified and overexpressed in cancer. Oncogene. 2003 Aug 07; 22(32):5070-81. PMID: 12902990.
      Citations: 43     Fields:    Translation:HumansCells
    315. Wills CJ, Scott A, Swift PG, Davies MJ, Mackie AD, Mansell P. Retrospective review of care and outcomes in young adults with type 1 diabetes. BMJ. 2003 Aug 02; 327(7409):260-1. PMID: 12896937.
      Citations: 22     Fields:    Translation:Humans
    316. Bowker TJ, Wood DA, Davies MJ, Sheppard MN, Cary NR, Burton JD, Chambers DR, Dawling S, Hobson HL, Pyke SD, Riemersma RA, Thompson SG. Sudden, unexpected cardiac or unexplained death in England: a national survey. QJM. 2003 Apr; 96(4):269-79. PMID: 12651971.
      Citations: 22     Fields:    Translation:Humans
    317. Woods AA, Linton SM, Davies MJ. Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques. Biochem J. 2003 Mar 01; 370(Pt 2):729-35. PMID: 12456264.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    318. Winter E, Wang J, Davies MJ, Norman R. Early pregnancy loss following assisted reproductive technology treatment. Hum Reprod. 2002 Dec; 17(12):3220-3. PMID: 12456627.
      Citations: 34     Fields:    Translation:Humans
    319. Hampton MB, Morgan PE, Davies MJ. Inactivation of cellular caspases by peptide-derived tryptophan and tyrosine peroxides. FEBS Lett. 2002 Sep 11; 527(1-3):289-92. PMID: 12220676.
      Citations: 9     Fields:    Translation:HumansCells
    320. Wang JX, Davies MJ, Norman RJ. Obesity increases the risk of spontaneous abortion during infertility treatment. Obes Res. 2002 Jun; 10(6):551-4. PMID: 12055331.
      Citations: 44     Fields:    Translation:Humans
    321. Davies MA, Kim SJ, Parikh NU, Dong Z, Bucana CD, Gallick GE. Adenoviral-mediated expression of MMAC/PTEN inhibits proliferation and metastasis of human prostate cancer cells. Clin Cancer Res. 2002 Jun; 8(6):1904-14. PMID: 12060635.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    322. Knott HM, Baoutina A, Davies MJ, Dean RT. Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein. Arch Biochem Biophys. 2002 Apr 15; 400(2):223-32. PMID: 12054433.
      Citations: 2     Fields:    Translation:HumansCells
    323. Koul D, Jasser SA, Lu Y, Davies MA, Shen R, Shi Y, Mills GB, Yung WK. Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity. Oncogene. 2002 Apr 04; 21(15):2357-64. PMID: 11948419.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    324. Shaw DM, Woods AM, Myers KA, Westwater C, Rahi-Saund V, Davies MJ, Renouf DV, Hounsell EF, Stern PL. Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen. Biochem J. 2002 Apr 01; 363(Pt 1):137-45. PMID: 11903056.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    325. Mahon NG, Madden BP, Caforio AL, Elliott PM, Haven AJ, Keogh BE, Davies MJ, McKenna WJ. Immunohistologic evidence of myocardial disease in apparently healthy relatives of patients with dilated cardiomyopathy. J Am Coll Cardiol. 2002 Feb 06; 39(3):455-62. PMID: 11823084.
      Citations: 19     Fields:    Translation:Humans
    326. Morin B, Fu S, Wang H, Davies MJ, Dean RT. Analysis of aliphatic amino acid alcohols in oxidized proteins. Methods Mol Biol. 2002; 186:101-10. PMID: 12013756.
      Citations:    Fields:    Translation:Cells
    327. Wang JX, Davies MJ, Norman RJ. Polycystic ovarian syndrome and the risk of spontaneous abortion following assisted reproductive technology treatment. Hum Reprod. 2001 Dec; 16(12):2606-9. PMID: 11726582.
      Citations: 34     Fields:    Translation:Humans
    328. Koul D, Parthasarathy R, Shen R, Davies MA, Jasser SA, Chintala SK, Rao JS, Sun Y, Benvenisite EN, Liu TJ, Yung WK. Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN. Oncogene. 2001 Oct 11; 20(46):6669-78. PMID: 11709701.
      Citations: 28     Fields:    Translation:HumansCells
    329. Varnava AM, Elliott PM, Baboonian C, Davison F, Davies MJ, McKenna WJ. Hypertrophic cardiomyopathy: histopathological features of sudden death in cardiac troponin T disease. Circulation. 2001 Sep 18; 104(12):1380-4. PMID: 11560853.
      Citations: 76     Fields:    Translation:Humans
    330. Norman RJ, Masters L, Milner CR, Wang JX, Davies MJ. Relative risk of conversion from normoglycaemia to impaired glucose tolerance or non-insulin dependent diabetes mellitus in polycystic ovarian syndrome. Hum Reprod. 2001 Sep; 16(9):1995-8. PMID: 11527911.
      Citations: 49     Fields:    Translation:Humans
    331. Knaapen MW, Davies MJ, De Bie M, Haven AJ, Martinet W, Kockx MM. Apoptotic versus autophagic cell death in heart failure. Cardiovasc Res. 2001 Aug 01; 51(2):304-12. PMID: 11470470.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    332. Smythe GM, Davies MJ, Paulin D, Grounds MD. Absence of desmin slightly prolongs myoblast proliferation and delays fusion in vivo in regenerating grafts of skeletal muscle. Cell Tissue Res. 2001 May; 304(2):287-94. PMID: 11396722.
      Citations: 11     Fields:    Translation:AnimalsCells
    333. Beresford SA, Davies MA, Gallick GE, Donato NJ. Differential effects of phosphatidylinositol-3/Akt-kinase inhibition on apoptotic sensitization to cytokines in LNCaP and PCc-3 prostate cancer cells. J Interferon Cytokine Res. 2001 May; 21(5):313-22. PMID: 11429162.
      Citations: 4     Fields:    Translation:HumansCells
    334. Tanaka M, Koul D, Davies MA, Liebert M, Steck PA, Grossman HB. MMAC1/PTEN inhibits cell growth and induces chemosensitivity to doxorubicin in human bladder cancer cells. Oncogene. 2000 Nov 09; 19(47):5406-12. PMID: 11103942.
      Citations: 30     Fields:    Translation:HumansCells
    335. Headlam HA, Mortimer A, Easton CJ, Davies MJ. beta-Scission of C-3 (beta-carbon) alkoxyl radicals on peptides and proteins: a novel pathway which results in the formation of alpha-carbon radicals and the loss of amino acid side chains. Chem Res Toxicol. 2000 Nov; 13(11):1087-95. PMID: 11087430.
      Citations: 11     Fields:    
    336. Davies MJ, Turner JG, Vives-Bauza C, Rumsby PC. Investigation of mutant frequency at the HPRT locus and changes in microsatellite sequences in healthy young adults. Mutat Res. 1999 Dec 17; 431(2):317-23. PMID: 10635997.
      Citations: 1     Fields:    Translation:HumansCells
    337. Davies MJ, Fu S, Wang H, Dean RT. Stable markers of oxidant damage to proteins and their application in the study of human disease. Free Radic Biol Med. 1999 Dec; 27(11-12):1151-63. PMID: 10641706.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    338. Lu Y, Lin YZ, LaPushin R, Cuevas B, Fang X, Yu SX, Davies MA, Khan H, Furui T, Mao M, Zinner R, Hung MC, Steck P, Siminovitch K, Mills GB. The PTEN/MMAC1/TEP tumor suppressor gene decreases cell growth and induces apoptosis and anoikis in breast cancer cells. Oncogene. 1999 Nov 25; 18(50):7034-45. PMID: 10597304.
      Citations: 85     Fields:    Translation:HumansCells
    339. Varnava A, Baboonian C, Davison F, de Cruz L, Elliott PM, Davies MJ, McKenna WJ. A new mutation of the cardiac troponin T gene causing familial hypertrophic cardiomyopathy without left ventricular hypertrophy. Heart. 1999 Nov; 82(5):621-4. PMID: 10525521.
      Citations: 17     Fields:    Translation:HumansCells
    340. Lauterio TJ, Davies MJ, DeAngelo M, Peyser M, Lee J. Neuropeptide Y expression and endogenous leptin concentrations in a dietary model of obesity. Obes Res. 1999 Sep; 7(5):498-505. PMID: 10509608.
      Citations: 1     Fields:    Translation:Animals
    341. Rayment NB, Haven AJ, Madden B, Murday A, Trickey R, Shipley M, Davies MJ, Katz DR. Myocyte loss in chronic heart failure. J Pathol. 1999 Jun; 188(2):213-9. PMID: 10398167.
      Citations: 12     Fields:    Translation:Humans
    342. Davies MA, Koul D, Dhesi H, Berman R, McDonnell TJ, McConkey D, Yung WK, Steck PA. Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN. Cancer Res. 1999 Jun 01; 59(11):2551-6. PMID: 10363971.
      Citations: 71     Fields:    Translation:Humans
    343. Delehedde M, Cho SH, Sarkiss M, Brisbay S, Davies M, El-Naggar AK, McDonnell TJ. Altered expression of bcl-2 family member proteins in nonmelanoma skin cancer. Cancer. 1999 Apr 01; 85(7):1514-22. PMID: 10193941.
      Citations: 8     Fields:    Translation:HumansCells
    344. Davies MJ, Muehlbayer S, Garrick P, McNally PG. Potential impact of a change in the diagnostic criteria for diabetes mellitus on the prevalence of abnormal glucose tolerance in a local community at risk of diabetes: impact of new diagnostic criteria for diabetes mellitus. Diabet Med. 1999 Apr; 16(4):343-6. PMID: 10220210.
      Citations: 3     Fields:    Translation:Humans
    345. Ramaswami G, Tegos T, Nicolaides AN, Dhanjil S, Griffin M, Al-Kutoubi A, Belcaro G, Lewis J, Wilkins R, Davies MJ. Ultrasonic plaque character and outcome after lower limb angioplasty. J Vasc Surg. 1999 Jan; 29(1):110-9; discussion 119-21. PMID: 9882795.
      Citations:    Fields:    Translation:Humans
    346. Davies MA, Lu Y, Sano T, Fang X, Tang P, LaPushin R, Koul D, Bookstein R, Stokoe D, Yung WK, Mills GB, Steck PA. Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis. Cancer Res. 1998 Dec 01; 58(23):5285-90. PMID: 9850049.
      Citations: 47     Fields:    Translation:HumansCells
    347. Morin B, Bubb WA, Davies MJ, Dean RT, Fu S. 3-Hydroxylysine, a potential marker for studying radical-induced protein oxidation. Chem Res Toxicol. 1998 Nov; 11(11):1265-73. PMID: 9815186.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    348. Park JI, Grant CM, Davies MJ, Dawes IW. The cytoplasmic Cu,Zn superoxide dismutase of saccharomyces cerevisiae is required for resistance to freeze-thaw stress. Generation of free radicals during freezing and thawing. J Biol Chem. 1998 Sep 04; 273(36):22921-8. PMID: 9722512.
      Citations: 23     Fields:    Translation:AnimalsCells
    349. Fu S, Davies MJ, Stocker R, Dean RT. Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque. Biochem J. 1998 Aug 01; 333 ( Pt 3):519-25. PMID: 9677308.
      Citations: 40     Fields:    Translation:HumansCells
    350. Davies MJ, Hounsell EF. HPLC and HPAEC of oligosaccharides and glycopeptides. Methods Mol Biol. 1998; 76:79-100. PMID: 9664348.
      Citations: 2     Fields:    
    351. Davies MJ, Smethurst DE, Howard KM, Todd M, Higgins LM, Bruce IJ. Improved manufacture and application of an agarose magnetizable solid-phase support. Appl Biochem Biotechnol. 1997 Oct-Nov; 68(1-2):95-112. PMID: 9373932.
      Citations: 1     Fields:    Translation:Cells
    352. Jeffery S, Kelling PJ, Lukaszyk A, Boriskin YS, Booth JC, Hodgson J, Davies MJ, McKenna WJ. Molecular evaluation of enteroviruses in the pathogenesis of idiopathic dilated cardiomyopathy. Clin Cardiol. 1997 Oct; 20(10):857-63. PMID: 9377822.
      Citations: 3     Fields:    Translation:HumansCells
    353. Hounsell EF, Young M, Davies MJ. Glycoprotein changes in tumours: a renaissance in clinical applications. Clin Sci (Lond). 1997 Oct; 93(4):287-93. PMID: 9404219.
      Citations: 7     Fields:    Translation:Humans
    354. Dean RT, Fu S, Stocker R, Davies MJ. Biochemistry and pathology of radical-mediated protein oxidation. Biochem J. 1997 May 15; 324 ( Pt 1):1-18. PMID: 9164834.
      Citations: 237     Fields:    Translation:HumansAnimalsCells
    355. Milross CG, Davies MA, Fisher R, Mameghan J, Mameghan H. The efficacy of treatment for malignant epidural spinal cord compression. Australas Radiol. 1997 May; 41(2):137-42. PMID: 9153809.
      Citations: 2     Fields:    Translation:Humans
    356. Routier FH, Davies MJ, Bergemann K, Hounsell EF. The glycosylation pattern of humanized IgGI antibody (D1.3) expressed in CHO cells. Glycoconj J. 1997 Feb; 14(2):201-7. PMID: 9111137.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    357. Slade GD, Spencer AJ, Davies MJ, Stewart JF. Caries experience among children in fluoridated Townsville and unfluoridated Brisbane. Aust N Z J Public Health. 1996 Dec; 20(6):623-9. PMID: 9117970.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    358. Tsui SS, Kirshbom PM, Davies MJ, Jacobs MT, Greeley WJ, Kern FH, Gaynor JW, Ungerleider RM. Nitric oxide production affects cerebral perfusion and metabolism after deep hypothermic circulatory arrest. Ann Thorac Surg. 1996 Jun; 61(6):1699-707. PMID: 8651770.
      Citations: 1     Fields:    Translation:Animals
    359. Slade GD, Spencer AJ, Davies MJ, Stewart JF. Influence of exposure to fluoridated water on socioeconomic inequalities in children's caries experience. Community Dent Oral Epidemiol. 1996 Apr; 24(2):89-100. PMID: 8654039.
      Citations: 11     Fields:    Translation:HumansPHPublic Health
    360. Davies MJ, Treasure T, Parker DJ. Demographic characteristics of patients undergoing aortic valve replacement for stenosis: relation to valve morphology. Heart. 1996 Feb; 75(2):174-8. PMID: 8673757.
      Citations: 13     Fields:    Translation:Humans
    361. Davies MJ, Phillips BJ, Rumsby PC. Molecular analysis of chemically-induced mutations in mammalian cell assays. Toxicol In Vitro. 1995 Aug; 9(4):513-8. PMID: 20650122.
      Citations: 1     Fields:    
    362. Maley MA, Davies MJ, Grounds MD. Extracellular matrix, growth factors, genetics: their influence on cell proliferation and myotube formation in primary cultures of adult mouse skeletal muscle. Exp Cell Res. 1995 Jul; 219(1):169-79. PMID: 7628533.
      Citations: 18     Fields:    Translation:AnimalsCells
    363. Davies MJ, Fu S, Dean RT. Protein hydroperoxides can give rise to reactive free radicals. Biochem J. 1995 Jan 15; 305 ( Pt 2):643-9. PMID: 7832784.
      Citations: 26     Fields:    
    364. Davies MJ, Ahmedzai S, Arsiwala SS, Leverment JN. Intracranial metastases from malignant pleural mesothelioma. Scand J Thorac Cardiovasc Surg. 1995; 29(2):97-9. PMID: 8643936.
      Citations: 2     Fields:    Translation:Humans
    365. Slade GD, Davies MJ, Spencer AJ, Stewart JF. Associations between exposure to fluoridated drinking water and dental caries experience among children in two Australian states. J Public Health Dent. 1995; 55(4):218-28. PMID: 8551461.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    366. Taylor T, Stonebridge PA, Allan PL, Kelman J, Andrade B, Davies MJ, Murie JA, Jenkins AM, Ruckley CV. Duplex ultrasound surveillance of infrainguinal bypass grafts: auditing the process. J R Coll Surg Edinb. 1994 Oct; 39(5):297-300. PMID: 7861339.
      Citations: 1     Fields:    Translation:Humans
    367. Davies MJ, Watson JD. An unusual case of distant colonic carcinoma metastasis. Postgrad Med J. 1994 Mar; 70(821):239-40. PMID: 8183766.
      Citations:    Fields:    Translation:Humans
    368. Rumsby PC, Davies MJ, Evans JG. Screening for p53 mutations in C3H/He mouse liver tumors derived spontaneously or induced with diethylnitrosamine or phenobarbitone. Mol Carcinog. 1994 Feb; 9(2):71-5. PMID: 8142011.
      Citations: 1     Fields:    Translation:AnimalsCells
    369. Davies MJ, Smith KD, Hounsell EF. The release of oligosaccharides from glycoproteins. Methods Mol Biol. 1994; 32:129-41. PMID: 7951717.
      Citations:    Fields:    
    370. Smith KD, Davies MJ, Hounsell EF. Structural profiling of oligosaccharides of glycoproteins. Methods Mol Biol. 1994; 32:143-55. PMID: 7951718.
      Citations: 1     Fields:    Translation:Cells
    371. Davies MJ, Silbert BS, Mooney PJ, Dysart RH, Meads AC. Combined epidural and general anaesthesia versus general anaesthesia for abdominal aortic surgery: a prospective randomised trial. Anaesth Intensive Care. 1993 Dec; 21(6):790-4. PMID: 8122735.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    372. Davies MJ, Phillips BJ, Rumsby PC. Molecular analysis of mutations at the tk locus of L5178Y mouse-lymphoma cells induced by ethyl methanesulphonate and mitomycin C. Mutat Res. 1993 Dec; 290(2):145-53. PMID: 7694105.
      Citations: 1     Fields:    Translation:AnimalsCells
    373. Timmins GS, Davies MJ. Free radical formation in murine skin treated with tumour promoting organic peroxides. Carcinogenesis. 1993 Aug; 14(8):1499-503. PMID: 8394776.
      Citations: 2     Fields:    Translation:Animals
    374. Davies MJ, Phillips BJ, Anderson D, Rumbsy PC. Molecular analysis of mutation at the hprt locus of Chinese hamster V79 cells induced by ethyl methanesulphonate and mitomycin C. Mutat Res. 1993 Apr; 291(2):117-24. PMID: 7680415.
      Citations:    Fields:    Translation:AnimalsCells
    375. Davies MJ, McGlade DP. One hundred sciatic nerve blocks: a comparison of localisation techniques. Anaesth Intensive Care. 1993 Feb; 21(1):76-8. PMID: 8447612.
      Citations: 1     Fields:    Translation:HumansCells
    376. Green ES, Evans H, Rice-Evans P, Davies MJ, Salah N, Rice-Evans C. The efficacy of monohydroxamates as free radical scavenging agents compared with di- and trihydroxamates. Biochem Pharmacol. 1993 Jan 26; 45(2):357-66. PMID: 8382062.
      Citations: 1     Fields:    Translation:HumansCells
    377. Keeling PJ, Jeffery S, Caforio AL, Taylor R, Bottazzo GF, Davies MJ, McKenna WJ. Similar prevalence of enteroviral genome within the myocardium from patients with idiopathic dilated cardiomyopathy and controls by the polymerase chain reaction. Br Heart J. 1992 Dec; 68(6):554-9. PMID: 1334684.
      Citations: 9     Fields:    Translation:HumansCells
    378. Davies MJ, Lovell DP, Anderson D. Thioguanine-resistant mutant frequency in T-lymphocytes from a healthy human population. Mutat Res. 1992 Feb; 265(2):165-71. PMID: 1370715.
      Citations: 7     Fields:    Translation:HumansCells
    379. Stewart JT, Nisbet JA, Davies MJ. Plasma endothelin in coronary venous blood from patients with either stable or unstable angina. Br Heart J. 1991 Jul; 66(1):7-9. PMID: 1854577.
      Citations: 3     Fields:    Translation:Humans
    380. de Feyter PJ, Serruys PW, Davies MJ, Richardson P, Lubsen J, Oliver MF. Quantitative coronary angiography to measure progression and regression of coronary atherosclerosis. Value, limitations, and implications for clinical trials. Circulation. 1991 Jul; 84(1):412-23. PMID: 2060112.
      Citations: 18     Fields:    Translation:Humans
    381. Stümper O, Fraser AG, Ho SY, Anderson RH, Chow L, Davies MJ, Roelandt JR, Sutherland GR. Transoesophageal echocardiography in the longitudinal axis: correlation between anatomy and images and its clinical implications. Br Heart J. 1990 Oct; 64(4):282-8. PMID: 2223308.
      Citations: 3     Fields:    Translation:Humans
    382. McKenna WJ, Stewart JT, Nihoyannopoulos P, McGinty F, Davies MJ. Hypertrophic cardiomyopathy without hypertrophy: two families with myocardial disarray in the absence of increased myocardial mass. Br Heart J. 1990 May; 63(5):287-90. PMID: 2278798.
      Citations: 37     Fields:    Translation:Humans
    383. Caforio AL, Stewart JT, Bonifacio E, Burke M, Davies MJ, McKenna WJ, Bottazzo GF. Inappropriate major histocompatibility complex expression on cardiac tissue in dilated cardiomyopathy. Relevance for autoimmunity? J Autoimmun. 1990 Apr; 3(2):187-200. PMID: 2187452.
      Citations: 11     Fields:    Translation:HumansCells
    384. Theaker JM, Gatter KC, Brown DC, Heryet A, Davies MJ. An investigation into the nature of giant cells in cardiac and skeletal muscle. Hum Pathol. 1988 Aug; 19(8):974-9. PMID: 3402987.
      Citations: 3     Fields:    Translation:Humans
    385. Stewart JT, Ward DE, Davies MJ, Pepper JR. Isolated coronary ostial stenosis: observations on the pathology. Eur Heart J. 1987 Aug; 8(8):917-20. PMID: 3665950.
      Citations: 3     Fields:    Translation:Humans
    386. Laing HC, Sharratt GP, Johnson AM, Davies MJ, Monro JL. Endomyocardial fibrosis in a European woman and its successful surgical treatment. J Thorac Cardiovasc Surg. 1977 Nov; 74(5):803-7. PMID: 916720.
      Citations: 3     Fields:    Translation:Humans
    387. Southall DP, Vulliamy DG, Davies MJ, Anderson RH, Shinebourne EA, Johnson AM. A new look at the neonatal electrocardiogram. Br Med J. 1976 Sep 11; 2(6036):615-8. PMID: 963463.
      Citations: 8     Fields:    Translation:Humans
    388. Woolf N, Sacks MI, Davies MJ. Aortic plaque morphology in relation to coronary artery disease. Am J Pathol. 1969 Oct; 57(1):187-97. PMID: 4899992.
      Citations:    Fields:    Translation:Humans
    389. Marks R, Davies MJ. The distribution in the skin of systemically administered tetracycline. Br J Dermatol. 1969 Jun; 81(6):448-51. PMID: 4239343.
      Citations: 1     Fields:    Translation:HumansAnimals
    390. Melanoma central nervous system metastases. Pigment Cell and Melanoma Research. 29:627-642.
    391. Clinicopathological features and clinical outcomes associated with TP53 and BRAFN on- V 600 mutations in cutaneous melanoma patients. Cancer.
    392. Molecular biology of cutaneous melanoma.
    393. Molecular biology of cutaneous melanoma.
    394. Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol. Annals of Oncology. 27:795-800.
    395. Intrathecal Administration of Tumor-Infiltrating Lymphocytes Is Well Tolerated in a Patient with Leptomeningeal Disease from Metastatic Melanoma. Cancer immunology research. 3:1201-1206.
    396. SBI-0640756 attenuates the growth of clinically unresponsive melanomas by disrupting the eIF4F translation initiation complex. Cancer Research. 75:5211-5218.
    397. Hotspot mutation panel testing reveals clonal evolution in a study of 265 paired primary and metastatic tumors. Clinical Cancer Research. 21:2644-2651.
    398. Role and complexity of next-generation sequencing in melanoma. Cancer cytopathology. 123:329-330.
    399. A phase I study of TPI 287 in combination with temozolomide for patients with metastatic melanoma. Melanoma Research.
    400. How do we make clinical molecular testing for cancer standard of care for pathology departments?. JNCCN Journal of the National Comprehensive Cancer Network. 14:787-792.
    401. Parallel and Serial Blockade Strategies in BRAF-Mutant Melanoma. Cancer Drug Discovery and Development. 82-168:105-135.
    402. Role of Increased n-acetylaspartate Levels in Cancer. Journal of the National Cancer Institute. 108.
    403. Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression. Scientific Reports. 6.
    404. An in vivo reporter to quantitatively and temporally analyze the effects of CDK4/6 inhibitor-based therapies in melanoma. Cancer Research. 76:5455-5466.
    405. PDK1 and SGK3 contribute to the growth of BRAF-mutant melanomas and are potential therapeutic targets. Cancer Research. 75:1399-1412.
    406. Erratum. Cancer Research. 59:1167.
    407. Novel algorithmic approach predicts tumor mutation load and correlates with immunotherapy clinical outcomes using a defined gene mutation set. BMC Medicine. 14.
    408. AKT1 Activation Promotes Development of Melanoma Metastases. Cell Reports. 13:898-905.
    409. Molecular approaches to tumor inhibition in melanoma. Clinical Advances in Hematology and Oncology. 13:831-833.
    410. Targeted therapy for melanoma. Oncogene. 33:1-9.
    411. Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics. PLoS One. 9.
    412. Bayesian sparse graphical models for classification with application to protein expression data. Annals of Applied Statistics. 8:1443-1468.
    413. Gas6/Axl is the sensor of arginine-auxotrophic response in targeted chemotherapy with arginine-depleting agents. Oncogene.
    414. Genotyping of cutaneous melanoma. Chinese Clinical Oncology. 3.
    415. Inflammatory marker testing identifies CD74 expression in melanoma tumor cells, and its expression associates with favorable survival for stage III melanoma. Clinical Cancer Research. 22:3016-3024.
    416. Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors. Journal of Clinical Investigation. 126:1834-1856.
    417. RMEL3, a novel BRAFV600E-associated long noncoding RNA, is required for MAPK and PI3K signaling in melanoma. Oncotarget. 7:36711-36718.
    418. Phase I dose-escalation study of the multikinase inhibitor lenvatinib in patients with advanced solid tumors and in an expanded cohort of patients with melanoma. Clinical Cancer Research. 21:4801-4810.
    419. Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade. Cancer Discovery. 6:827-837.
    420. BRAFV600E co-opts a conserved MHC class I internalization pathway to diminish antigen presentation and CD8+ T-cell recognition of melanoma. Cancer immunology research. 3:602-609.
    421. The multi-faceted roles of the PI3K-AKT pathway in melanoma. Journal of Translational Medicine. 1.
    422. Cancer Discovery. 6:202-216.
    423. RAC1 P29S regulates PD-L1 expression in melanoma. Pigment Cell and Melanoma Research. 28:590-598.
    424. Factors predictive of response, disease progression, and overall survival after dabrafenib and trametinib combination treatment. The Lancet Oncology. 17:1743-1754.
    425. Integrated molecular and clinical analysis of AKT activation in metastatic melanoma. Clinical Cancer Research. 15:7538-7546.
    426. Feasibility of large-scale genomic testing to facilitate enrollment onto genomically matched clinical trials. Journal of Clinical Oncology. 33:2753-2762.
    427. Distinct clinical patterns and immune infiltrates are observed at time of progression on targeted therapy versus immune checkpoint blockade for melanoma. OncoImmunology. 5.
    428. Targeting Notch enhances the efficacy of ERK inhibitors in BRAFV600E melanoma. Oncotarget. 7:71211-71222.
    429. Future perspectives in melanoma research. Journal of Translational Medicine. 13.
    430. Future perspectives in melanoma research. Journal of Translational Medicine. 14.
    431. Erratum. PLoS One. 8.
    432. MIG6 Is MEK Regulated and Affects EGF-Induced Migration in Mutant NRAS Melanoma. Journal of Investigative Dermatology. 136:453-463.
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