DAVID RANDALL GROSSHANS

TitleAssociate Professor
InstitutionMD Anderson
DepartmentRadiation Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Tang TT, Zawaski JA, Kesler S, Beamish CA, Inoue T, Perez EC, Bronk L, Poenisch F, Briere TM, Sabek OM, Grosshans DR, Waleed Gaber M. Cognitive and Imaging Differences After Proton and Photon Whole Brain Irradiation in a Preclinical Model. Int J Radiat Oncol Biol Phys. 2021 Sep 09. PMID: 34509550.
      Citations:    Fields:    
    2. Brown PD, Chung C, Liu DD, McAvoy S, Grosshans D, Al Feghali K, Mahajan A, Li J, McGovern SL, McAleer MF, Ghia AJ, Sulman EP, Penas-Prado M, de Groot JF, Heimberger AB, Wang J, Armstrong TS, Gilbert MR, Guha-Thakurta N, Wefel JS. A prospective phase II randomized trial of proton radiotherapy vs intensity-modulated radiotherapy for patients with newly diagnosed glioblastoma. Neuro Oncol. 2021 08 02; 23(8):1337-1347. PMID: 33647972.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    3. Spiotto MT, McGovern SL, Gunn GB, Grosshans D, McAleer MF, Frank SJ, Paulino AC. Proton Radiotherapy to Reduce Late Complications in Childhood Head and Neck Cancers. Int J Part Ther. 2021; 8(1):155-167. PMID: 34285943.
      Citations:    
    4. Child AE, Warren EA, Grosshans DR, Paulino AC, Okcu MF, Ris MD, Mahajan A, Orobio J, Cirino PT, Minard CG, Viana AG, Bick J, Woods SP, Chintagumpala M, Kahalley LS. Long-term cognitive and academic outcomes among pediatric brain tumor survivors treated with proton versus photon radiotherapy. Pediatr Blood Cancer. 2021 Sep; 68(9):e29125. PMID: 34114294.
      Citations:    Fields:    
    5. Skaarup M, Lundemann MJ, Darkner S, Jørgensen M, Marner L, Mirkovic D, Grosshans D, Peeler C, Mohan R, Vogelius IR, Appelt A. A framework for voxel-based assessment of biological effect after proton radiotherapy in pediatric brain cancer patients using multi-modal imaging. Med Phys. 2021 Jul; 48(7):4110-4121. PMID: 34021597.
      Citations: 1     Fields:    Translation:HumansCells
    6. Al Feghali KA, Randall JW, Liu DD, Wefel JS, Brown PD, Grosshans DR, McAvoy SA, Farhat MA, Li J, McGovern SL, McAleer MF, Ghia AJ, Paulino AC, Sulman EP, Penas-Prado M, Wang J, de Groot J, Heimberger AB, Armstrong TS, Gilbert MR, Mahajan A, Guha-Thakurta N, Chung C. Phase II trial of proton therapy versus photon IMRT for GBM: secondary analysis comparison of progression-free survival between RANO versus clinical assessment. Neurooncol Adv. 2021 Jan-Dec; 3(1):vdab073. PMID: 34337411.
      Citations:    
    7. Milgrom SA, van Luijk P, Pino R, Ronckers CM, Kremer LC, Gidley PW, Grosshans DR, Laskar S, Okcu MF, Constine LS, Paulino AC. Salivary and Dental Complications in Childhood Cancer Survivors Treated With Radiation Therapy to the Head and Neck: A Pediatric Normal Tissue Effects in the Clinic (PENTEC) Comprehensive Review. Int J Radiat Oncol Biol Phys. 2021 May 29. PMID: 34074567.
      Citations: 1     Fields:    
    8. Heitzer AM, Kahalley LS, Minard CG, Stafford C, Grosshans DR, Okcu MF, Raghubar KP, Gragert M, McCurdy M, Warren EH, Gomez J, Ris MD, Paulino AC, Chintagumpala M. Treatment age and neurocognitive outcomes following proton beam radiotherapy for pediatric low- and intermediate-grade gliomas. Pediatr Blood Cancer. 2021 Aug; 68(8):e29096. PMID: 34019329.
      Citations:    Fields:    
    9. Oyefiade A, Paltin I, De Luca CR, Hardy KK, Grosshans DR, Chintagumpala M, Mabbott DJ, Kahalley LS. Cognitive Risk in Survivors of Pediatric Brain Tumors. J Clin Oncol. 2021 06 01; 39(16):1718-1726. PMID: 33886348.
      Citations:    Fields:    Translation:Humans
    10. Hanania AN, Paulino AC, Ludmir EB, Shah VS, Su JM, McGovern SL, Baxter PA, McAleer MF, Grosshans DR, Okcu MF, Chintagumpala MM. Early radiotherapy preserves vision in sporadic optic pathway glioma. Cancer. 2021 Jul 01; 127(13):2358-2367. PMID: 33739455.
      Citations:    Fields:    
    11. Nantavithya C, Paulino AC, Liao K, Woodhouse KD, McGovern SL, Grosshans DR, McAleer MF, Khatua S, Chintagumpala MM, Majd N, Zaky W, Yeboa DN. Observed-to-expected incidence ratios of second malignant neoplasms after radiation therapy for medulloblastoma: A Surveillance, Epidemiology, and End Results analysis. Cancer. 2021 Jul 01; 127(13):2368-2375. PMID: 33721338.
      Citations:    Fields:    
    12. Bishop AJ, Livingston JA, Ning MS, Valdez ID, Wages CA, McAleer MF, Paulino AC, Grosshans DR, Woodhouse KD, Tao R, Roth ME, Gunn GB, McGovern SL. Young Adult Populations Face Yet Another Barrier to Care With Insurers: Limited Access to Proton Therapy. Int J Radiat Oncol Biol Phys. 2021 08 01; 110(5):1496-1504. PMID: 33677051.
      Citations:    Fields:    Translation:Humans
    13. Buszek SM, Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Disease Control and Patterns of Failure After Proton Beam Therapy for Rhabdomyosarcoma. Int J Radiat Oncol Biol Phys. 2021 03 01; 109(3):718-725. PMID: 33516439.
      Citations:    Fields:    Translation:Humans
    14. Mohan R, Liu AY, Brown PD, Mahajan A, Dinh J, Chung C, McAvoy S, McAleer MF, Lin SH, Li J, Ghia AJ, Zhu C, Sulman EP, de Groot JF, Heimberger AB, McGovern SL, Grassberger C, Shih H, Ellsworth S, Grosshans DR. Proton therapy reduces the likelihood of high-grade radiation-induced lymphopenia in glioblastoma patients: phase II randomized study of protons vs photons. Neuro Oncol. 2021 02 25; 23(2):284-294. PMID: 32750703.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    15. Liu SM, Brooks ED, Rubin ML, Grosshans DR, Frank SJ, McAleer MF, McGovern SL, Paulino AC, Woodhouse KD. Referral Patterns and Treatment Delays in Medulloblastoma: A Large Academic Proton Center Experience. Int J Part Ther. 2021; 7(3):1-10. PMID: 33604411.
      Citations:    
    16. Beamish CA, Zawaski JA, Inoue T, Sarkar P, Grosshans DR, Sabek OM, Gaber MW. NF-?B Blockade by NEMO Binding Domain Peptide Ameliorates Inflammation and Neurobehavioral Sequelae After Cranial Radiation Therapy in Juvenile Mice. Int J Radiat Oncol Biol Phys. 2021 04 01; 109(5):1508-1520. PMID: 33307152.
      Citations:    Fields:    Translation:Animals
    17. Bronk L, Guan F, Patel D, Ma D, Kroger B, Wang X, Tran K, Yiu J, Stephan C, Debus J, Abdollahi A, Jäkel O, Mohan R, Titt U, Grosshans DR. Mapping the Relative Biological Effectiveness of Proton, Helium and Carbon Ions with High-Throughput Techniques. Cancers (Basel). 2020 Dec 05; 12(12). PMID: 33291477.
      Citations: 3     
    18. Paganetti H, Beltran CJ, Both S, Dong L, Flanz JB, Furutani KM, Grassberger C, Grosshans DR, Knopf AC, Langendijk JA, Nyström H, Parodi K, Raaymakers BW, Richter C, Sawakuchi GO, Schippers JM, Shaitelman SF, Teo K, Unkelbach J, Wohlfahrt P, Lomax AJ. Roadmap: proton therapy physics and biology. Phys Med Biol. 2020 Nov 23. PMID: 33227715.
      Citations: 1     Fields:    
    19. Abolfath R, Grosshans D, Mohan R. Oxygen depletion in FLASH ultra-high-dose-rate radiotherapy: A molecular dynamics simulation. Med Phys. 2020 Dec; 47(12):6551-6561. PMID: 33089504.
      Citations: 1     Fields:    Translation:Cells
    20. Lin TA, Ludmir EB, Liao KP, McAleer MF, Bishop AJ, Grosshans D, McGovern S, Woodhouse KD, Paulino AC, Yeboa DN. Relationship between treatment center case volume and survival for localized Ewing sarcoma: The role of radiotherapy timing. Pediatr Blood Cancer. 2020 11; 67(11):e28685. PMID: 32881378.
      Citations:    Fields:    Translation:Humans
    21. Bai X, Lim G, Grosshans D, Mohan R, Cao W. A biological effect-guided optimization approach using beam distal-edge avoidance for intensity-modulated proton therapy. Med Phys. 2020 Sep; 47(9):3816-3825. PMID: 32557747.
      Citations: 2     Fields:    Translation:HumansCells
    22. Vassiliev ON, Peterson CB, Grosshans DR, Mohan R. A simple model for calculating relative biological effectiveness of X-rays and gamma radiation in cell survival. Br J Radiol. 2020 Aug; 93(1112):20190949. PMID: 32464080.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    23. Noticewala SS, Ludmir EB, Bishop AJ, Chung C, Ghia AJ, Grosshans D, McGovern S, Paulino AC, Wang C, Woodhouse KD, Yeboa DN, Prabhu SS, Weathers SP, Das P, Koong AC, McAleer MF, Li J. Radiation for Glioblastoma in the Era of Coronavirus Disease 2019 (COVID-19): Patient Selection and Hypofractionation to Maximize Benefit and Minimize Risk. Adv Radiat Oncol. 2020 Jul-Aug; 5(4):743-745. PMID: 32775785.
      Citations: 3     
    24. Zhang D, Zhou W, Lam TT, Li Y, Duman JG, Dougherty PM, Grosshans DR. Cranial irradiation induces axon initial segment dysfunction and neuronal injury in the prefrontal cortex and impairs hippocampal coupling. Neurooncol Adv. 2020 Jan-Dec; 2(1):vdaa058. PMID: 32642710.
      Citations:    
    25. Kahalley LS, Peterson R, Ris MD, Janzen L, Okcu MF, Grosshans DR, Ramaswamy V, Paulino AC, Hodgson D, Mahajan A, Tsang DS, Laperriere N, Whitehead WE, Dauser RC, Taylor MD, Bouffet E, Chintagumpala M, Mabbott D. Reply to S.A. Milgrom et al. J Clin Oncol. 2020 07 01; 38(19):2212-2213. PMID: 32374644.
      Citations: 1     Fields:    Translation:Humans
    26. Ma D, Bronk L, Kerr M, Sobieski M, Chen M, Geng C, Yiu J, Wang X, Sahoo N, Cao W, Zhang X, Stephan C, Mohan R, Grosshans DR, Guan F. Exploring the advantages of intensity-modulated proton therapy: experimental validation of biological effects using two different beam intensity-modulation patterns. Sci Rep. 2020 02 21; 10(1):3199. PMID: 32081928.
      Citations: 2     Fields:    Translation:HumansCells
    27. Brown PD, Gondi V, Pugh S, Tome WA, Wefel JS, Armstrong TS, Bovi JA, Robinson C, Konski A, Khuntia D, Grosshans D, Benzinger TLS, Bruner D, Gilbert MR, Roberge D, Kundapur V, Devisetty K, Shah S, Usuki K, Anderson BM, Stea B, Yoon H, Li J, Laack NN, Kruser TJ, Chmura SJ, Shi W, Deshmukh S, Mehta MP, Kachnic LA. Hippocampal Avoidance During Whole-Brain Radiotherapy Plus Memantine for Patients With Brain Metastases: Phase III Trial NRG Oncology CC001. J Clin Oncol. 2020 04 01; 38(10):1019-1029. PMID: 32058845.
      Citations: 83     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    28. Abolfath R, Peeler C, Mirkovic D, Mohan R, Grosshans D. A DNA damage multiscale model for NTCP in proton and hadron therapy. Med Phys. 2020 Apr; 47(4):2005-2012. PMID: 31955444.
      Citations:    Fields:    Translation:Humans
    29. Raghubar KP, Rothhaar MC, Yeates KO, Mahone EM, Grosshans DR, Scheurer ME, Ris MD. Premorbid functioning as a predictor of outcome in pediatric brain tumor: An initial examination of the normalcy assumption. Pediatr Blood Cancer. 2020 04; 67(4):e28135. PMID: 31886612.
      Citations:    Fields:    Translation:Humans
    30. Kahalley LS, Peterson R, Ris MD, Janzen L, Okcu MF, Grosshans DR, Ramaswamy V, Paulino AC, Hodgson D, Mahajan A, Tsang DS, Laperriere N, Whitehead WE, Dauser RC, Taylor MD, Conklin HM, Chintagumpala M, Bouffet E, Mabbott D. Superior Intellectual Outcomes After Proton Radiotherapy Compared With Photon Radiotherapy for Pediatric Medulloblastoma. J Clin Oncol. 2020 02 10; 38(5):454-461. PMID: 31774710.
      Citations: 29     Fields:    Translation:HumansPHPublic Health
    31. Bright SJ, Flint DB, Chakraborty S, McFadden CH, Yoon DS, Bronk L, Titt U, Mohan R, Grosshans DR, Sumazin P, Shaitelman SF, Asaithamby A, Sawakuchi GO. Nonhomologous End Joining Is More Important Than Proton Linear Energy Transfer in Dictating Cell Death. Int J Radiat Oncol Biol Phys. 2019 12 01; 105(5):1119-1125. PMID: 31425731.
      Citations: 4     Fields:    Translation:HumansCells
    32. Buszek SM, Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Patterns of failure and toxicity profile following proton beam therapy for pediatric bladder and prostate rhabdomyosarcoma. Pediatr Blood Cancer. 2019 11; 66(11):e27952. PMID: 31397065.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    33. Ludmir EB, Mahajan A, Ahern V, Ajithkumar T, Alapetite C, Bernier-Chastagner V, Bindra RS, Bishop AJ, Bolle S, Brown PD, Carrie C, Chalmers AJ, Chang EL, Chung C, Dieckmann K, Esiashvili N, Gandola L, Ghia AJ, Gondi V, Grosshans DR, Harrabi SB, Horan G, Indelicato DJ, Jalali R, Janssens GO, Krause M, Laack NN, Laperriere N, Laprie A, Li J, Marcus KJ, McGovern SL, Merchant TE, Merrell KW, Padovani L, Parkes J, Paulino AC, Schwarz R, Shih HA, Souhami L, Sulman EP, Taylor RE, Thorp N, Timmermann B, Wheeler G, Wolden SL, Woodhouse KD, Yeboa DN, Yock TI, Kortmann RD, McAleer MF. Assembling the brain trust: the multidisciplinary imperative in neuro-oncology. Nat Rev Clin Oncol. 2019 08; 16(8):521-522. PMID: 31150024.
      Citations:    Fields:    Translation:Humans
    34. Darne CD, Alsanea F, Robertson DG, Guan F, Pan T, Grosshans D, Beddar S. A proton imaging system using a volumetric liquid scintillator: a preliminary study. Biomed Phys Eng Express. 2019 Jul; 5(4). PMID: 32194988.
      Citations:    
    35. Tang TT, Zawaski JA, Kesler SR, Beamish CA, Reddick WE, Glass JO, Carney DH, Sabek OM, Grosshans DR, Gaber MW. A comprehensive preclinical assessment of late-term imaging markers of radiation-induced brain injury. Neurooncol Adv. 2019 May-Dec; 1(1):vdz012. PMID: 31608330.
      Citations: 2     
    36. Kahalley LS, Douglas Ris M, Mahajan A, Fatih Okcu M, Chintagumpala M, Paulino AC, Whitehead WE, Minard CG, Stancel HH, Orobio J, Xue JJ, Warren EA, Grosshans DR. Prospective, longitudinal comparison of neurocognitive change in pediatric brain tumor patients treated with proton radiotherapy versus surgery only. Neuro Oncol. 2019 06 10; 21(6):809-818. PMID: 30753584.
      Citations: 11     Fields:    Translation:Humans
    37. Amsbaugh MJ, Mahajan A, Thall PF, McAleer MF, Paulino AC, Grosshans D, Khatua S, Ketonen L, Fontanilla H, McGovern SL. In Reply to Krishnatry and Manjali. Int J Radiat Oncol Biol Phys. 2019 06 01; 104(2):468-469. PMID: 31047634.
      Citations:    Fields:    Translation:Humans
    38. Ludmir EB, Mahajan A, Paulino AC, Jones JY, Ketonen LM, Su JM, Grosshans DR, McAleer MF, McGovern SL, Lassen-Ramshad YA, Adesina AM, Dauser RC, Weinberg JS, Chintagumpala MM. Increased risk of pseudoprogression among pediatric low-grade glioma patients treated with proton versus photon radiotherapy. Neuro Oncol. 2019 05 06; 21(5):686-695. PMID: 30753704.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    39. Bagley AF, Grosshans DR, Philip NV, Foster J, McAleer MF, McGovern SL, Lassen-Ramshad Y, Mahajan A, Paulino AC. Efficacy of proton therapy in children with high-risk and locally recurrent neuroblastoma. Pediatr Blood Cancer. 2019 08; 66(8):e27786. PMID: 31050179.
      Citations: 5     Fields:    Translation:Humans
    40. Cao W, Khabazian A, Yepes P, Lim G, Poenisch F, Grosshans D, Mohan R. Reply to Comment on 'Linear energy transfer incorporated intensity modulated proton therapy optimization'. Phys Med Biol. 2019 02 27; 64(5):058002. PMID: 30811349.
      Citations:    Fields:    Translation:Cells
    41. Evans LT, DeMonte F, Grosshans DR, Ghia AJ, Habib A, Raza SM. Salvage Therapy for Local Progression following Definitive Therapy for Skull Base Chordomas: Is There a Role of Stereotactic Radiosurgery? J Neurol Surg B Skull Base. 2020 Feb; 81(1):97-106. PMID: 32021756.
      Citations:    
    42. Paganetti H, Blakely E, Carabe-Fernandez A, Carlson DJ, Das IJ, Dong L, Grosshans D, Held KD, Mohan R, Moiseenko V, Niemierko A, Stewart RD, Willers H. Report of the AAPM TG-256 on the relative biological effectiveness of proton beams in radiation therapy. Med Phys. 2019 Mar; 46(3):e53-e78. PMID: 30661238.
      Citations: 27     Fields:    Translation:Humans
    43. Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Patterns of failure following proton beam therapy for head and neck rhabdomyosarcoma. Radiother Oncol. 2019 05; 134:143-150. PMID: 31005208.
      Citations: 3     Fields:    Translation:Humans
    44. Newpower M, Patel D, Bronk L, Guan F, Chaudhary P, McMahon SJ, Prise KM, Schettino G, Grosshans DR, Mohan R. Using the Proton Energy Spectrum and Microdosimetry to Model Proton Relative Biological Effectiveness. Int J Radiat Oncol Biol Phys. 2019 06 01; 104(2):316-324. PMID: 30731186.
      Citations: 5     Fields:    Translation:Cells
    45. Bai X, Lim G, Grosshans D, Mohan R, Cao W. Robust optimization to reduce the impact of biological effect variation from physical uncertainties in intensity-modulated proton therapy. Phys Med Biol. 2019 01 08; 64(2):025004. PMID: 30523932.
      Citations: 6     Fields:    Translation:HumansCells
    46. Durante M, Paganetti H, Pompos A, Kry SF, Wu X, Grosshans DR. Report of a National Cancer Institute special panel: Characterization of the physical parameters of particle beams for biological research. Med Phys. 2019 Feb; 46(2):e37-e52. PMID: 30506898.
      Citations: 3     Fields:    
    47. Buszek SM, Ikner S, Wiedemann L, Wang J, McAleer MF, Grosshans DR, Paulino AC, McGovern SL, Chung C. Safety and Feasibility of Magnetic Resonance Imaging Simulation for Radiation Treatment Planning in Pediatric Patients: A Single Institution Experience. Adv Radiat Oncol. 2019 Apr-Jun; 4(2):362-366. PMID: 31011682.
      Citations: 1     
    48. Guan F, Geng C, Carlson DJ, Ma DH, Bronk L, Gates D, Wang X, Kry SF, Grosshans D, Mohan R. A mechanistic relative biological effectiveness model-based biological dose optimization for charged particle radiobiology studies. Phys Med Biol. 2018 12 21; 64(1):015008. PMID: 30523805.
      Citations: 1     Fields:    Translation:Humans
    49. Ning MS, Gomez DR, Shah AK, Kim CR, Palmer MB, Thaker NG, Grosshans DR, Liao Z, Chapman BV, Brooks ED, Tang C, Rosenthal DI, Garden AS, Frank SJ, Gunn GB. The Insurance Approval Process for Proton Radiation Therapy: A Significant Barrier to Patient Care. Int J Radiat Oncol Biol Phys. 2019 07 15; 104(4):724-733. PMID: 30557675.
      Citations: 13     Fields:    Translation:Humans
    50. Yepes P, Adair A, Frank SJ, Grosshans DR, Liao Z, Liu A, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Fixed- versus Variable-RBE Computations for Intensity Modulated Proton Therapy. Adv Radiat Oncol. 2019 Jan-Mar; 4(1):156-167. PMID: 30706024.
      Citations: 3     
    51. Stoker J, Vora S, Patel A, Grosshans D, Brown PD, Vern-Gross T, Bues M, Daniels T, Allred B, Uejo A, Kosiorek H, Bruso M, Keole S. Advantages of intensity modulated proton therapy during hippocampal avoidance whole brain radiation therapy. Phys Imaging Radiat Oncol. 2018 Oct; 8:28-32. PMID: 33458413.
      Citations: 2     
    52. Jaramillo S, Grosshans DR, Philip N, Varan A, Akyüz C, McAleer MF, Mahajan A, McGovern SL. Radiation for ETMR: Literature review and case series of patients treated with proton therapy. Clin Transl Radiat Oncol. 2019 Feb; 15:31-37. PMID: 30582019.
      Citations: 6     
    53. Grosshans DR, Duman JG, Gaber MW, Sawakuchi G. Particle Radiation Induced Neurotoxicity in the Central Nervous System. Int J Part Ther. 2018; 5(1):74-83. PMID: 31773021.
      Citations: 2     
    54. Guan F, Geng C, Ma D, Bronk L, Kerr M, Li Y, Gates D, Kroger B, Sahoo N, Titt U, Grosshans D, Mohan R. RBE Model-Based Biological Dose Optimization for Proton Radiobiology Studies. Int J Part Ther. 2018; 5(1):160-171. PMID: 30338268.
      Citations: 7     
    55. Vatner RE, Niemierko A, Misra M, Weyman EA, Goebel CP, Ebb DH, Jones RM, Huang MS, Mahajan A, Grosshans DR, Paulino AC, Stanley T, MacDonald SM, Tarbell NJ, Yock TI. Endocrine Deficiency As a Function of Radiation Dose to the Hypothalamus and Pituitary in Pediatric and Young Adult Patients With Brain Tumors. J Clin Oncol. 2018 10 01; 36(28):2854-2862. PMID: 30118397.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    56. Raza SM, Bell D, Freeman JL, Grosshans DR, Fuller GN, DeMonte F. Multimodality Management of Recurrent Skull Base Chordomas: Factors Impacting Tumor Control and Disease-Specific Survival. Oper Neurosurg (Hagerstown). 2018 08 01; 15(2):131-143. PMID: 29040778.
      Citations: 3     Fields:    Translation:Humans
    57. Grosshans DR, Brown PD. Chemotherapy Plus Proton or Photon Radiation on a Trial. Int J Radiat Oncol Biol Phys. 2018 07 01; 101(3):518-519. PMID: 29893270.
      Citations:    Fields:    Translation:Humans
    58. Willers H, Allen A, Grosshans D, McMahon SJ, von Neubeck C, Wiese C, Vikram B. Toward A variable RBE for proton beam therapy. Radiother Oncol. 2018 07; 128(1):68-75. PMID: 29910006.
      Citations: 21     Fields:    Translation:HumansCells
    59. Haas-Kogan D, Indelicato D, Paganetti H, Esiashvili N, Mahajan A, Yock T, Flampouri S, MacDonald S, Fouladi M, Stephen K, Kalapurakal J, Terezakis S, Kooy H, Grosshans D, Makrigiorgos M, Mishra K, Poussaint TY, Cohen K, Fitzgerald T, Gondi V, Liu A, Michalski J, Mirkovic D, Mohan R, Perkins S, Wong K, Vikram B, Buchsbaum J, Kun L. National Cancer Institute Workshop on Proton Therapy for Children: Considerations Regarding Brainstem Injury. Int J Radiat Oncol Biol Phys. 2018 05 01; 101(1):152-168. PMID: 29619963.
      Citations: 26     Fields:    Translation:HumansCellsPHPublic Health
    60. Duman JG, Dinh J, Zhou W, Cham H, Mavratsas VC, Paveškovic M, Mulherkar S, McGovern SL, Tolias KF, Grosshans DR. Memantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses. Neuro Oncol. 2018 04 09; 20(5):655-665. PMID: 29112734.
      Citations: 10     Fields:    Translation:AnimalsCellsPHPublic Health
    61. Wilke C, Grosshans D, Duman J, Brown P, Li J. Radiation-induced cognitive toxicity: pathophysiology and interventions to reduce toxicity in adults. Neuro Oncol. 2018 04 09; 20(5):597-607. PMID: 29045710.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    62. Vassiliev ON, Kry SF, Grosshans DR, Mohan R. Average stopping powers for electron and photon sources for radiobiological modeling and microdosimetric applications. Phys Med Biol. 2018 03 02; 63(5):055007. PMID: 29411712.
      Citations: 2     Fields:    Translation:Humans
    63. Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Erratum: "Monte Carlo simulations of 3 He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness" [Med. Phys. 43 (2), page range 761-776(2016)]. Med Phys. 2018 Mar; 45(3):1301. PMID: 29527699.
      Citations:    Fields:    
    64. Yepes P, Adair A, Grosshans D, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Comparison of Monte Carlo and analytical dose computations for intensity modulated proton therapy. Phys Med Biol. 2018 02 09; 63(4):045003. PMID: 29339570.
      Citations: 10     Fields:    Translation:Humans
    65. Ludmir EB, Paulino AC, Grosshans DR, McAleer MF, McGovern SL, Huh WW, Okcu MF, Harrell LM, Mahajan A. Regional Nodal Control for Head and Neck Alveolar Rhabdomyosarcoma. Int J Radiat Oncol Biol Phys. 2018 05 01; 101(1):169-176. PMID: 29477293.
      Citations:    Fields:    Translation:Humans
    66. Paulino AC, Mahajan A, Ye R, Grosshans DR, Fatih Okcu M, Su J, McAleer MF, McGovern S, Mangona VA, Chintagumpala M. Ototoxicity and cochlear sparing in children with medulloblastoma: Proton vs. photon radiotherapy. Radiother Oncol. 2018 07; 128(1):128-132. PMID: 29373195.
      Citations: 5     Fields:    Translation:Humans
    67. Bronk JK, Guha-Thakurta N, Allen PK, Mahajan A, Grosshans DR, McGovern SL. Analysis of pseudoprogression after proton or photon therapy of 99 patients with low grade and anaplastic glioma. Clin Transl Radiat Oncol. 2018 Feb; 9:30-34. PMID: 29594248.
      Citations: 7     
    68. Mohan R, Held KD, Story MD, Grosshans D, Capala J. Proceedings of the National Cancer Institute Workshop on Charged Particle Radiobiology. Int J Radiat Oncol Biol Phys. 2018 03 15; 100(4):816-831. PMID: 29485053.
      Citations: 3     Fields:    Translation:Humans
    69. Cao W, Khabazian A, Yepes PP, Lim G, Poenisch F, Grosshans DR, Mohan R. Linear energy transfer incorporated intensity modulated proton therapy optimization. Phys Med Biol. 2017 12 19; 63(1):015013. PMID: 29131808.
      Citations: 13     Fields:    Translation:HumansCells
    70. Vassiliev ON, Grosshans DR, Mohan R. A new formalism for modelling parameters a and ß of the linear-quadratic model of cell survival for hadron therapy. Phys Med Biol. 2017 Oct 03; 62(20):8041-8059. PMID: 28832343.
      Citations: 4     Fields:    Translation:HumansCells
    71. Chun SG, Solberg TD, Grosshans DR, Nguyen QN, Simone CB, Mohan R, Liao Z, Hahn SM, Herman JM, Frank SJ. The Potential of Heavy-Ion Therapy to Improve Outcomes for Locally Advanced Non-Small Cell Lung Cancer. Front Oncol. 2017; 7:201. PMID: 28929085.
      Citations: 2     
    72. Raza SM, Gidley PW, Meis JM, Grosshans DR, Bell D, DeMonte F. Multimodality Treatment of Skull Base Chondrosarcomas: The Role of Histology Specific Treatment Protocols. Neurosurgery. 2017 Sep 01; 81(3):520-530. PMID: 28368506.
      Citations: 6     Fields:    Translation:Humans
    73. Mohan R, Peeler CR, Guan F, Bronk L, Cao W, Grosshans DR. Radiobiological issues in proton therapy. Acta Oncol. 2017 Nov; 56(11):1367-1373. PMID: 28826292.
      Citations: 15     Fields:    Translation:Humans
    74. Abolfath R, Peeler CR, Newpower M, Bronk L, Grosshans D, Mohan R. A model for relative biological effectiveness of therapeutic proton beams based on a global fit of cell survival data. Sci Rep. 2017 08 21; 7(1):8340. PMID: 28827691.
      Citations: 5     Fields:    Translation:HumansCells
    75. Antonini TN, Ris MD, Grosshans DR, Mahajan A, Okcu MF, Chintagumpala M, Paulino A, Child AE, Orobio J, Stancel HH, Kahalley LS. Attention, processing speed, and executive functioning in pediatric brain tumor survivors treated with proton beam radiation therapy. Radiother Oncol. 2017 07; 124(1):89-97. PMID: 28655455.
      Citations: 16     Fields:    Translation:HumansPHPublic Health
    76. Grosshans DR, Mohan R, Gondi V, Shih HA, Mahajan A, Brown PD. The role of image-guided intensity modulated proton therapy in glioma. Neuro Oncol. 2017 04 01; 19(suppl_2):ii30-ii37. PMID: 28380636.
      Citations: 4     Fields:    Translation:Humans
    77. Hou P, Zhu KH, Park PC, Li H, Mahajan A, Grosshans DR. Proton Therapy for Juvenile Pilocytic Astrocytoma: Quantifying Treatment Responses by Magnetic Resonance Diffusion Tensor Imaging. Int J Part Ther. 2017; 3(3):414-420. PMID: 31772991.
      Citations: 1     
    78. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 31772982.
      Citations: 1     
    79. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 32453481.
      Citations: 1     Fields:    Translation:Humans
    80. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 31736188.
      Citations: 2     Fields:    Translation:Humans
    81. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 31772961.
      Citations:    
    82. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 31134755.
      Citations: 3     Fields:    Translation:Humans
    83. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 31553958.
      Citations: 1     Fields:    
    84. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 29856521.
      Citations: 5     Fields:    Translation:Humans
    85. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 27919760.
      Citations: 56     Fields:    Translation:Humans
    86. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 28880368.
      Citations: 6     Fields:    Translation:HumansCells
    87. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 26830376.
      Citations: 1     Fields:    Translation:Humans
    88. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 27189523.
      Citations: 32     Fields:    Translation:Humans
    89. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 29236051.
      Citations:    
    90. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 30610915.
      Citations: 7     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    91. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 29527697.
      Citations:    Fields:    
    92. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 30656222.
      Citations: 2     
    93. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 30593906.
      Citations: 4     Fields:    Translation:Humans
    94. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 30400370.
      Citations: 5     
    95. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 26811522.
      Citations: 43     Fields:    Translation:Humans
    96. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 29660023.
      Citations: 5     Fields:    Translation:AnimalsCellsPHPublic Health
    97. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 25521400.
      Citations: 21     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    98. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 21635776.
      Citations: 23     Fields:    Translation:Humans
    99. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 22245209.
      Citations: 15     Fields:    Translation:HumansPHPublic Health
    100. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 23433794.
      Citations: 38     Fields:    Translation:Humans
    101. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 17728388.
      Citations: 9     Fields:    Translation:AnimalsCells
    102. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 22662188.
      Citations: 26     Fields:    Translation:AnimalsCells
    103. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 12072555.
      Citations: 27     Fields:    Translation:Animals
    104. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 24560754.
      Citations: 5     Fields:    Translation:Humans
    105. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 33127998.
      Citations: 2     Fields:    
    106. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 33837540.
      Citations:    Fields:    Translation:HumansCells
    107. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 34254296.
      Citations:    Fields:    
    108. Peeler CR, Mirkovic D, Titt U, Blanchard P, Gunther JR, Mahajan A, Mohan R, Grosshans DR. Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma. Radiother Oncol. 2016 12; 121(3):395-401. PMID: 27863964.
      Citations: 47     Fields:    Translation:HumansCells
    109. Greenfield BJ, Jaramillo S, Abboud M, Mahajan A, Paulino AC, McGovern S, McAleer MF, Chintagumpala M, Okcu MF, Khatua S, Su J, Grosshans DR. Outcomes for pediatric patients with central nervous system germ cell tumors treated with proton therapy. Clin Transl Radiat Oncol. 2016 Dec; 1:9-14. PMID: 29657988.
      Citations: 3     
    110. Wang X, Poenisch F, Sahoo N, Zhu RX, Lii M, Gillin MT, Li J, Grosshans D. Spot scanning proton therapy minimizes neutron dose in the setting of radiation therapy administered during pregnancy. J Appl Clin Med Phys. 2016 09 08; 17(5):366-376. PMID: 27685136.
      Citations: 3     Fields:    Translation:Humans
    111. Jiang S, Wang J, Li H, Liao L, Li Y, Wang X, Yang Y, Zhu RX, Sahoo N, Gillin MT, Hojo Y, Sun J, Chang JY, Liao Z, Grosshans D, Frank SJ, Zhang X. Novel Hybrid Scattering- and Scanning-Beam Proton Therapy Approach. Int J Part Ther. 2016; 3(1):37-50. PMID: 31772974.
      Citations:    
    112. Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Monte Carlo simulations of ³He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness. Med Phys. 2016 Feb; 43(2):761-76. PMID: 26843239.
      Citations: 3     Fields:    
    113. Owusu-Agyemang P, Popovich SM, Zavala AM, Grosshans DR, Van Meter A, Williams UU, Holmes AA, Arunkumar R, Rebello E, McAleer MF, Porche V, Mahajan A. A multi-institutional pilot survey of anesthesia practices during proton radiation therapy. Pract Radiat Oncol. 2016 May-Jun; 6(3):155-159. PMID: 26725965.
      Citations: 2     Fields:    Translation:Humans
    114. Guan F, Peeler C, Bronk L, Geng C, Taleei R, Randeniya S, Ge S, Mirkovic D, Grosshans D, Mohan R, Titt U. Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code. Med Phys. 2015 Nov; 42(11):6234-47. PMID: 26520716.
      Citations: 24     Fields:    Translation:HumansCells
    115. Munck af Rosenschold P, Engelholm SA, Brodin PN, Jørgensen M, Grosshans DR, Zhu RX, Palmer M, Crawford CN, Mahajan A. A Retrospective Evaluation of the Benefit of Referring Pediatric Cancer Patients to an External Proton Therapy Center. Pediatr Blood Cancer. 2016 Feb; 63(2):262-9. PMID: 26397177.
      Citations: 3     Fields:    Translation:Humans
    116. Grant SR, Grosshans DR, Bilton SD, Garcia JA, Amin M, Chambers MS, McGovern SL, McAleer MF, Morrison WH, Huh WW, Kupferman ME, Mahajan A. Proton versus conventional radiotherapy for pediatric salivary gland tumors: Acute toxicity and dosimetric characteristics. Radiother Oncol. 2015 Aug; 116(2):309-15. PMID: 26232128.
      Citations: 9     Fields:    Translation:Humans
    117. Guan F, Bronk L, Titt U, Lin SH, Mirkovic D, Kerr MD, Zhu XR, Dinh J, Sobieski M, Stephan C, Peeler CR, Taleei R, Mohan R, Grosshans DR. Spatial mapping of the biologic effectiveness of scanned particle beams: towards biologically optimized particle therapy. Sci Rep. 2015 May 18; 5:9850. PMID: 25984967.
      Citations: 35     Fields:    Translation:HumansCells
    118. Holliday EB, Mitra HS, Somerson JS, Rhines LD, Mahajan A, Brown PD, Grosshans DR. Postoperative proton therapy for chordomas and chondrosarcomas of the spine: adjuvant versus salvage radiation therapy. Spine (Phila Pa 1976). 2015 Apr 15; 40(8):544-9. PMID: 25627289.
      Citations: 11     Fields:    Translation:Humans
    119. Day J, Zienius K, Gehring K, Grosshans D, Taphoorn M, Grant R, Li J, Brown PD. Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation. Cochrane Database Syst Rev. 2014 Dec 18; (12):CD011335. PMID: 25519950.
      Citations: 13     Fields:    Translation:Humans
    120. McGovern SL, Grosshans D, Mahajan A. Embryonal brain tumors. Cancer J. 2014 Nov-Dec; 20(6):397-402. PMID: 25415685.
      Citations: 5     Fields:    Translation:Humans
    121. Ladra MM, Szymonifka JD, Mahajan A, Friedmann AM, Yong Yeap B, Goebel CP, MacDonald SM, Grosshans DR, Rodriguez-Galindo C, Marcus KJ, Tarbell NJ, Yock TI. Preliminary results of a phase II trial of proton radiotherapy for pediatric rhabdomyosarcoma. J Clin Oncol. 2014 Nov 20; 32(33):3762-70. PMID: 25332253.
      Citations: 28     Fields:    Translation:HumansCTClinical Trials
    122. Ladra MM, Edgington SK, Mahajan A, Grosshans D, Szymonifka J, Khan F, Moteabbed M, Friedmann AM, MacDonald SM, Tarbell NJ, Yock TI. A dosimetric comparison of proton and intensity modulated radiation therapy in pediatric rhabdomyosarcoma patients enrolled on a prospective phase II proton study. Radiother Oncol. 2014 Oct; 113(1):77-83. PMID: 25443861.
      Citations: 20     Fields:    Translation:HumansCTClinical Trials
    123. McGovern SL, Okcu MF, Munsell MF, Kumbalasseriyil N, Grosshans DR, McAleer MF, Chintagumpala M, Khatua S, Mahajan A. Outcomes and acute toxicities of proton therapy for pediatric atypical teratoid/rhabdoid tumor of the central nervous system. Int J Radiat Oncol Biol Phys. 2014 Dec 01; 90(5):1143-52. PMID: 25311260.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    124. Grosshans DR, Zhu XR, Melancon A, Allen PK, Poenisch F, Palmer M, McAleer MF, McGovern SL, Gillin M, DeMonte F, Chang EL, Brown PD, Mahajan A. Spot scanning proton therapy for malignancies of the base of skull: treatment planning, acute toxicities, and preliminary clinical outcomes. Int J Radiat Oncol Biol Phys. 2014 Nov 01; 90(3):540-6. PMID: 25304948.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    125. Zhu XR, Poenisch F, Li H, Zhang X, Sahoo N, Wu RY, Li X, Lee AK, Chang EL, Choi S, Pugh T, Frank SJ, Gillin MT, Mahajan A, Grosshans DR. A single-field integrated boost treatment planning technique for spot scanning proton therapy. Radiat Oncol. 2014 Sep 11; 9:202. PMID: 25212571.
      Citations: 8     Fields:    Translation:Humans
    126. Stoker JB, Grant J, Zhu XR, Pidikiti R, Mahajan A, Grosshans DR. Intensity modulated proton therapy for craniospinal irradiation: organ-at-risk exposure and a low-gradient junctioning technique. Int J Radiat Oncol Biol Phys. 2014 Nov 01; 90(3):637-44. PMID: 25194667.
      Citations: 6     Fields:    Translation:Humans
    127. LeRoux LG, Bredow S, Grosshans D, Schellingerhout D. Molecular imaging detects impairment in the retrograde axonal transport mechanism after radiation-induced spinal cord injury. Mol Imaging Biol. 2014 Aug; 16(4):504-10. PMID: 24395625.
      Citations: 2     Fields:    Translation:AnimalsPHPublic Health
    128. Bishop AJ, Greenfield B, Mahajan A, Paulino AC, Okcu MF, Allen PK, Chintagumpala M, Kahalley LS, McAleer MF, McGovern SL, Whitehead WE, Grosshans DR. Proton beam therapy versus conformal photon radiation therapy for childhood craniopharyngioma: multi-institutional analysis of outcomes, cyst dynamics, and toxicity. Int J Radiat Oncol Biol Phys. 2014 Oct 01; 90(2):354-61. PMID: 25052561.
      Citations: 25     Fields:    Translation:Humans
    129. Shao Y, Sun X, Lou K, Zhu XR, Mirkovic D, Poenisch F, Grosshans D. In-beam PET imaging for on-line adaptive proton therapy: an initial phantom study. Phys Med Biol. 2014 Jul 07; 59(13):3373-88. PMID: 24874943.
      Citations: 8     Fields:    
    130. Liu W, Mohan R, Park P, Liu Z, Li H, Li X, Li Y, Wu R, Sahoo N, Dong L, Zhu XR, Grosshans DR. Dosimetric benefits of robust treatment planning for intensity modulated proton therapy for base-of-skull cancers. Pract Radiat Oncol. 2014 Nov-Dec; 4(6):384-91. PMID: 25407859.
      Citations: 21     Fields:    Translation:Humans
    131. Dinh J, Stoker J, Georges RH, Sahoo N, Zhu XR, Rath S, Mahajan A, Grosshans DR. Comparison of proton therapy techniques for treatment of the whole brain as a component of craniospinal radiation. Radiat Oncol. 2013 Dec 17; 8:289. PMID: 24344645.
      Citations: 3     Fields:    Translation:Humans
    132. Barney CL, Brown AP, Grosshans DR, McAleer MF, de Groot JF, Puduvalli V, Tucker SL, Crawford CN, Gilbert MR, Brown PD, Mahajan A. Technique, outcomes, and acute toxicities in adults treated with proton beam craniospinal irradiation. Neuro Oncol. 2014 Jan; 16(2):303-9. PMID: 24311638.
      Citations: 7     Fields:    Translation:Humans
    133. Tucker SL, Liao Z, Dinh J, Bian SX, Mohan R, Martel MK, Grosshans DR. Is there an impact of heart exposure on the incidence of radiation pneumonitis? Analysis of data from a large clinical cohort. Acta Oncol. 2014 May; 53(5):590-6. PMID: 23992110.
      Citations: 9     Fields:    Translation:Humans
    134. Bian SX, McAleer MF, Vats TS, Mahajan A, Grosshans DR. Pilocytic astrocytoma with leptomeningeal dissemination. Childs Nerv Syst. 2013 Mar; 29(3):441-50. PMID: 23207974.
      Citations: 9     Fields:    Translation:Humans
    135. Sharp H, Grosshans D, Kadia T, Dabaja BS. Cutaneous graft-versus-host disease after proton-based craniospinal irradiation for recurrent Philadelphia-positive acute lymphoblastic leukaemia. BMJ Case Rep. 2012 Jul 11; 2012. PMID: 22787181.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    136. Amsbaugh MJ, Zhu XR, Palmer M, Poenisch F, McAleer MF, Mahajan A, Grosshans DR. Spot scanning proton therapy for craniopharyngioma. Pract Radiat Oncol. 2012 Oct-Dec; 2(4):314-318. PMID: 24674170.
      Citations: 2     Fields:    
    137. Boehling NS, Grosshans DR, Allen PK, McAleer MF, Burton AW, Azeem S, Rhines LD, Chang EL. Vertebral compression fracture risk after stereotactic body radiotherapy for spinal metastases. J Neurosurg Spine. 2012 Apr; 16(4):379-86. PMID: 22225488.
      Citations: 53     Fields:    Translation:Humans
    138. Pinnix CC, Fontanilla HP, Hayes-Jordan A, Subbiah V, Bilton SD, Chang EL, Grosshans DR, McAleer MF, Sulman EP, Woo SY, Anderson P, Green HL, Mahajan A. Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery. Int J Radiat Oncol Biol Phys. 2012 May 01; 83(1):317-26. PMID: 22104361.
      Citations: 19     Fields:    Translation:Humans
    139. Grosshans D, Boehling NS, Palmer M, Spicer C, Erice R, Cox JD, Komaki R, Chang JY. Improving cardiac dosimetry: Alternative beam arrangements for intensity modulated radiation therapy planning in patients with carcinoma of the distal esophagus. Pract Radiat Oncol. 2012 Jan-Mar; 2(1):41-5. PMID: 24674035.
      Citations: 6     Fields:    
    140. Boehling NS, Grosshans DR, Bluett JB, Palmer MT, Song X, Amos RA, Sahoo N, Meyer JJ, Mahajan A, Woo SY. Dosimetric comparison of three-dimensional conformal proton radiotherapy, intensity-modulated proton therapy, and intensity-modulated radiotherapy for treatment of pediatric craniopharyngiomas. Int J Radiat Oncol Biol Phys. 2012 Feb 01; 82(2):643-52. PMID: 21277111.
      Citations: 44     Fields:    Translation:Humans
    141. Grosshans DR, Meyers CA, Allen PK, Davenport SD, Komaki R. Neurocognitive function in patients with small cell lung cancer : effect of prophylactic cranial irradiation. Cancer. 2008 Feb 01; 112(3):589-95. PMID: 18098269.
      Citations: 31     Fields:    Translation:HumansCTClinical Trials
    142. Alvestad RM, Grosshans DR, Coultrap SJ, Nakazawa T, Yamamoto T, Browning MD. Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function. J Biol Chem. 2003 Mar 28; 278(13):11020-5. PMID: 12536146.
      Citations: 35     Fields:    Translation:AnimalsCells
    143. Clayton DA, Grosshans DR, Browning MD. Aging and surface expression of hippocampal NMDA receptors. J Biol Chem. 2002 Apr 26; 277(17):14367-9. PMID: 11891215.
      Citations: 27     Fields:    Translation:Animals
    144. Grosshans DR, Clayton DA, Coultrap SJ, Browning MD. LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci. 2002 Jan; 5(1):27-33. PMID: 11740502.
      Citations: 121     Fields:    Translation:AnimalsCells
    145. Grosshans DR, Browning MD. Protein kinase C activation induces tyrosine phosphorylation of the NR2A and NR2B subunits of the NMDA receptor. J Neurochem. 2001 Feb; 76(3):737-44. PMID: 11158244.
      Citations: 23     Fields:    Translation:AnimalsCells
    146. Oh JJ, Grosshans DR, Wong SG, Slamon DJ. Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells. Nucleic Acids Res. 1999 Oct 15; 27(20):4008-17. PMID: 10497265.
      Citations: 31     Fields:    Translation:HumansCells
    147. Péterfy M, Gyuris T, Grosshans D, Cuaresma CC, Takács L. Cloning and characterization of cDNAs and the gene encoding the mouse platelet-activating factor acetylhydrolase Ib alpha subunit/lissencephaly-1 protein. Genomics. 1998 Jan 15; 47(2):200-6. PMID: 9479492.
      Citations: 4     Fields:    Translation:AnimalsCells
    148. Chang Ms, McNinch J, Elias C, Manthey CL, Grosshans D, Meng T, Boone T, Andrew DP. Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes. J Biol Chem. 1997 Oct 03; 272(40):25229-37. PMID: 9312138.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    149. Wilson CA, Payton MN, Elliott GS, Buaas FW, Cajulis EE, Grosshans D, Ramos L, Reese DM, Slamon DJ, Calzone FJ. Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b. Oncogene. 1997 Jan 09; 14(1):1-16. PMID: 9010228.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    150. Spot scanning proton therapy for craniopharyngioma. Practical Radiation Oncology. 2:314-318.
    151. Spatial mapping of the biologic effectiveness of scanned particle beams. Scientific Reports. 5.
    152. Spot scanning proton therapy minimizes neutron dose in the setting of radiation therapy administered during pregnancy. Journal of Applied Clinical Medical Physics. 17:366-376.
    153. Catechol-o-methyltransferase genotype modulates cancer treatment-related cognitive deficits in breast cancer survivors. Breast Diseases. 22:411-412.
    154. A multi-institutional pilot survey of anesthesia practices during proton radiation therapy. Practical Radiation Oncology.
    155. Particle therapy for central nervous system tumors in pediatric and adult patients. Translational Cancer Research. 1:137-149.
    156. Comparing intelligence quotient change after treatment with proton versus photon radiation therapy for pediatric brain tumors. Journal of Clinical Oncology. 34:1043-1049.
    157. Proton therapy - Present and future. Advanced Drug Delivery Reviews.
    158. Cutaneous graft-versus-host disease after proton-based craniospinal irradiation for recurrent Philadelphia-positive acute lymphoblastic leukaemia. BMJ Case Reports.
    159. Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma. Radiotherapy and Oncology. 121:395-401.
    160. Proton therapy for paediatric medulloblastoma. The Lancet Oncology. 17:258-259.
    161. Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant 4 Monte Carlo code. Medical Physics. 42:6234-6247.
    162. Impact of heart and lung dose on early survival in patients with non-small cell lung cancer treated with chemoradiation. Radiotherapy and Oncology.
    163. Proton versus conventional radiotherapy for pediatric salivary gland tumors. Radiotherapy and Oncology.
    164. Improving cardiac dosimetry. Practical Radiation Oncology. 2:41-45.
    165. Monte Carlo simulations of 3He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness. Medical Physics. 43:761-776.
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