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DAVID RANDALL GROSSHANS

TitleAssociate Professor
InstitutionMD Anderson
DepartmentRadiation Oncology
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kahalley LS, Peterson R, Ris MD, Janzen L, Okcu MF, Grosshans DR, Ramaswamy V, Paulino AC, Hodgson D, Mahajan A, Tsang DS, Laperriere N, Whitehead WE, Dauser RC, Taylor MD, Conklin HM, Chintagumpala M, Bouffet E, Mabbott D. Superior Intellectual Outcomes After Proton Radiotherapy Compared With Photon Radiotherapy for Pediatric Medulloblastoma. J Clin Oncol. 2019 Nov 27; JCO1901706. PMID: 31774710.
      View in: PubMed
    2. Roth AK, Ris MD, Orobio J, Xue J, Mahajan A, Paulino AC, Grosshans D, Okcu MF, Chintagumpala M, Kahalley LS. Cognitive mediators of adaptive functioning outcomes in survivors of pediatric brain tumors treated with proton radiotherapy. Pediatr Blood Cancer. 2019 Nov 17; e28064. PMID: 31736188.
      View in: PubMed
    3. Vassiliev ON, Peterson CB, Cao W, Grosshans DR, Mohan R. Systematic microdosimetric data for protons of therapeutic energies calculated with Geant4-DNA. Phys Med Biol. 2019 Nov 04; 64(21):215018. PMID: 31553958.
      View in: PubMed
    4. Bright SJ, Flint DB, Chakraborty S, McFadden CH, Yoon DS, Bronk L, Titt U, Mohan R, Grosshans DR, Sumazin P, Shaitelman SF, Asaithamby A, Sawakuchi GO. Nonhomologous End Joining Is More Important Than Proton Linear Energy Transfer in Dictating Cell Death. Int J Radiat Oncol Biol Phys. 2019 Dec 01; 105(5):1119-1125. PMID: 31425731.
      View in: PubMed
    5. Buszek SM, Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Patterns of failure and toxicity profile following proton beam therapy for pediatric bladder and prostate rhabdomyosarcoma. Pediatr Blood Cancer. 2019 Nov; 66(11):e27952. PMID: 31397065.
      View in: PubMed
    6. Ludmir EB, Mahajan A, Ahern V, Ajithkumar T, Alapetite C, Bernier-Chastagner V, Bindra RS, Bishop AJ, Bolle S, Brown PD, Carrie C, Chalmers AJ, Chang EL, Chung C, Dieckmann K, Esiashvili N, Gandola L, Ghia AJ, Gondi V, Grosshans DR, Harrabi SB, Horan G, Indelicato DJ, Jalali R, Janssens GO, Krause M, Laack NN, Laperriere N, Laprie A, Li J, Marcus KJ, McGovern SL, Merchant TE, Merrell KW, Padovani L, Parkes J, Paulino AC, Schwarz R, Shih HA, Souhami L, Sulman EP, Taylor RE, Thorp N, Timmermann B, Wheeler G, Wolden SL, Woodhouse KD, Yeboa DN, Yock TI, Kortmann RD, McAleer MF. Assembling the brain trust: the multidisciplinary imperative in neuro-oncology. Nat Rev Clin Oncol. 2019 08; 16(8):521-522. PMID: 31150024.
      View in: PubMed
    7. Tang TT, Zawaski JA, Kesler SR, Beamish CA, Reddick WE, Glass JO, Carney DH, Sabek OM, Grosshans DR, Gaber MW. A comprehensive preclinical assessment of late-term imaging markers of radiation-induced brain injury. Neurooncol Adv. 2019 May-Dec; 1(1):vdz012. PMID: 31608330.
      View in: PubMed
    8. Kahalley LS, Douglas Ris M, Mahajan A, Fatih Okcu M, Chintagumpala M, Paulino AC, Whitehead WE, Minard CG, Stancel HH, Orobio J, Xue JJ, Warren EA, Grosshans DR. Prospective, longitudinal comparison of neurocognitive change in pediatric brain tumor patients treated with proton radiotherapy versus surgery only. Neuro Oncol. 2019 Jun 10; 21(6):809-818. PMID: 30753584.
      View in: PubMed
    9. Amsbaugh MJ, Mahajan A, Thall PF, McAleer MF, Paulino AC, Grosshans D, Khatua S, Ketonen L, Fontanilla H, McGovern SL. In Reply to Krishnatry and Manjali. Int J Radiat Oncol Biol Phys. 2019 06 01; 104(2):468-469. PMID: 31047634.
      View in: PubMed
    10. Raghubar KP, Orobio J, Ris MD, Heitzer AM, Roth A, Brown AL, Okcu MF, Chintagumpala M, Grosshans DR, Paulino AC, Mahajan A, Kahalley LS. Adaptive functioning in pediatric brain tumor survivors: An examination of ethnicity and socioeconomic status. Pediatr Blood Cancer. 2019 Sep; 66(9):e27800. PMID: 31134755.
      View in: PubMed
    11. Ludmir EB, Mahajan A, Paulino AC, Jones JY, Ketonen LM, Su JM, Grosshans DR, McAleer MF, McGovern SL, Lassen-Ramshad YA, Adesina AM, Dauser RC, Weinberg JS, Chintagumpala MM. Increased risk of pseudoprogression among pediatric low-grade glioma patients treated with proton versus photon radiotherapy. Neuro Oncol. 2019 May 06; 21(5):686-695. PMID: 30753704.
      View in: PubMed
    12. Bagley AF, Grosshans DR, Philip NV, Foster J, McAleer MF, McGovern SL, Lassen-Ramshad Y, Mahajan A, Paulino AC. Efficacy of proton therapy in children with high-risk and locally recurrent neuroblastoma. Pediatr Blood Cancer. 2019 Aug; 66(8):e27786. PMID: 31050179.
      View in: PubMed
    13. Cao W, Khabazian A, Yepes P, Lim G, Poenisch F, Grosshans D, Mohan R. Reply to Comment on 'Linear energy transfer incorporated intensity modulated proton therapy optimization'. Phys Med Biol. 2019 02 27; 64(5):058002. PMID: 30811349.
      View in: PubMed
    14. Ludmir EB, Grosshans DR, McAleer MF, McGovern SL, Harrison DJ, Okcu MF, Chintagumpala MM, Mahajan A, Paulino AC. Patterns of failure following proton beam therapy for head and neck rhabdomyosarcoma. Radiother Oncol. 2019 May; 134:143-150. PMID: 31005208.
      View in: PubMed
    15. Paganetti H, Blakely E, Carabe-Fernandez A, Carlson DJ, Das IJ, Dong L, Grosshans D, Held KD, Mohan R, Moiseenko V, Niemierko A, Stewart RD, Willers H. Report of the AAPM TG-256 on the relative biological effectiveness of proton beams in radiation therapy. Med Phys. 2019 Mar; 46(3):e53-e78. PMID: 30661238.
      View in: PubMed
    16. Newpower M, Patel D, Bronk L, Guan F, Chaudhary P, McMahon SJ, Prise KM, Schettino G, Grosshans DR, Mohan R. Using the Proton Energy Spectrum and Microdosimetry to Model Proton Relative Biological Effectiveness. Int J Radiat Oncol Biol Phys. 2019 06 01; 104(2):316-324. PMID: 30731186.
      View in: PubMed
    17. Bai X, Lim G, Grosshans D, Mohan R, Cao W. Robust optimization to reduce the impact of biological effect variation from physical uncertainties in intensity-modulated proton therapy. Phys Med Biol. 2019 01 08; 64(2):025004. PMID: 30523932.
      View in: PubMed
    18. Amsbaugh MJ, Mahajan A, Thall PF, McAleer MF, Paulino AC, Grosshans D, Khatua S, Ketonen L, Fontanilla H, McGovern SL. A Phase 1/2 Trial of Reirradiation for Diffuse Intrinsic Pontine Glioma. Int J Radiat Oncol Biol Phys. 2019 05 01; 104(1):144-148. PMID: 30610915.
      View in: PubMed
    19. Durante M, Paganetti H, Pompos A, Kry SF, Wu X, Grosshans DR. Report of a National Cancer Institute special panel: Characterization of the physical parameters of particle beams for biological research. Med Phys. 2019 Feb; 46(2):e37-e52. PMID: 30506898.
      View in: PubMed
    20. Yeboa DN, Yu JB, Liao E, Huse J, Penas-Prado M, Kann BH, Sulman E, Grosshans D, Contessa J. Differences in patterns of care and outcomes between grade II and grade III molecularly defined 1p19q co-deleted gliomas. Clin Transl Radiat Oncol. 2019 Feb; 15:46-52. PMID: 30656222.
      View in: PubMed
    21. Lin TA, Ludmir EB, Liao KP, McAleer MF, Grosshans DR, McGovern SL, Bishop AJ, Woodhouse KD, Paulino AC, Yeboa DN. Timing of Local Therapy Affects Survival in Ewing Sarcoma. Int J Radiat Oncol Biol Phys. 2019 05 01; 104(1):127-136. PMID: 30593906.
      View in: PubMed
    22. Guan F, Geng C, Carlson DJ, Ma DH, Bronk L, Gates D, Wang X, Kry SF, Grosshans D, Mohan R. A mechanistic relative biological effectiveness model-based biological dose optimization for charged particle radiobiology studies. Phys Med Biol. 2018 12 21; 64(1):015008. PMID: 30523805.
      View in: PubMed
    23. Buszek SM, Ikner S, Wiedemann L, Wang J, McAleer MF, Grosshans DR, Paulino AC, McGovern SL, Chung C. Safety and Feasibility of Magnetic Resonance Imaging Simulation for Radiation Treatment Planning in Pediatric Patients: A Single Institution Experience. Adv Radiat Oncol. 2019 Apr-Jun; 4(2):362-366. PMID: 31011682.
      View in: PubMed
    24. Ning MS, Gomez DR, Shah AK, Kim CR, Palmer MB, Thaker NG, Grosshans DR, Liao Z, Chapman BV, Brooks ED, Tang C, Rosenthal DI, Garden AS, Frank SJ, Gunn GB. The Insurance Approval Process for Proton Radiation Therapy: A Significant Barrier to Patient Care. Int J Radiat Oncol Biol Phys. 2019 Jul 15; 104(4):724-733. PMID: 30557675.
      View in: PubMed
    25. Yepes P, Adair A, Frank SJ, Grosshans DR, Liao Z, Liu A, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Fixed- versus Variable-RBE Computations for Intensity Modulated Proton Therapy. Adv Radiat Oncol. 2019 Jan-Mar; 4(1):156-167. PMID: 30706024.
      View in: PubMed
    26. Jaramillo S, Grosshans DR, Philip N, Varan A, Akyüz C, McAleer MF, Mahajan A, McGovern SL. Radiation for ETMR: Literature review and case series of patients treated with proton therapy. Clin Transl Radiat Oncol. 2019 Feb; 15:31-37. PMID: 30582019.
      View in: PubMed
    27. Ludmir EB, Grosshans DR, Woodhouse KD. Radiotherapy Advances in Pediatric Neuro-Oncology. Bioengineering (Basel). 2018 Nov 04; 5(4). PMID: 30400370.
      View in: PubMed
    28. Guan F, Geng C, Ma D, Bronk L, Kerr M, Li Y, Gates D, Kroger B, Sahoo N, Titt U, Grosshans D, Mohan R. RBE Model-Based Biological Dose Optimization for Proton Radiobiology Studies. Int J Part Ther. 2018; 5(1):160-171. PMID: 30338268.
      View in: PubMed
    29. Grosshans DR, Duman JG, Gaber MW, Sawakuchi G. Particle Radiation Induced Neurotoxicity in the Central Nervous System. Int J Part Ther. 2018; 5(1):74-83. PMID: 31773021.
      View in: PubMed
    30. Vatner RE, Niemierko A, Misra M, Weyman EA, Goebel CP, Ebb DH, Jones RM, Huang MS, Mahajan A, Grosshans DR, Paulino AC, Stanley T, MacDonald SM, Tarbell NJ, Yock TI. Endocrine Deficiency As a Function of Radiation Dose to the Hypothalamus and Pituitary in Pediatric and Young Adult Patients With Brain Tumors. J Clin Oncol. 2018 10 01; 36(28):2854-2862. PMID: 30118397.
      View in: PubMed
    31. Zhang D, Zhou W, Lam TT, Weng C, Bronk L, Ma D, Wang Q, Duman JG, Dougherty PM, Grosshans DR. Radiation induces age-dependent deficits in cortical synaptic plasticity. Neuro Oncol. 2018 08 02; 20(9):1207-1214. PMID: 29660023.
      View in: PubMed
    32. Raza SM, Bell D, Freeman JL, Grosshans DR, Fuller GN, DeMonte F. Multimodality Management of Recurrent Skull Base Chordomas: Factors Impacting Tumor Control and Disease-Specific Survival. Oper Neurosurg (Hagerstown). 2018 08 01; 15(2):131-143. PMID: 29040778.
      View in: PubMed
    33. Grosshans DR, Brown PD. Chemotherapy Plus Proton or Photon Radiation on a Trial. Int J Radiat Oncol Biol Phys. 2018 07 01; 101(3):518-519. PMID: 29893270.
      View in: PubMed
    34. Willers H, Allen A, Grosshans D, McMahon SJ, von Neubeck C, Wiese C, Vikram B. Toward A variable RBE for proton beam therapy. Radiother Oncol. 2018 07; 128(1):68-75. PMID: 29910006.
      View in: PubMed
    35. Raghubar KP, Lamba M, Cecil KM, Yeates KO, Mahone EM, Limke C, Grosshans D, Beckwith TJ, Ris MD. Dose-volume metrics and their relation to memory performance in pediatric brain tumor patients: A preliminary study. Pediatr Blood Cancer. 2018 09; 65(9):e27245. PMID: 29856521.
      View in: PubMed
    36. Haas-Kogan D, Indelicato D, Paganetti H, Esiashvili N, Mahajan A, Yock T, Flampouri S, MacDonald S, Fouladi M, Stephen K, Kalapurakal J, Terezakis S, Kooy H, Grosshans D, Makrigiorgos M, Mishra K, Poussaint TY, Cohen K, Fitzgerald T, Gondi V, Liu A, Michalski J, Mirkovic D, Mohan R, Perkins S, Wong K, Vikram B, Buchsbaum J, Kun L. National Cancer Institute Workshop on Proton Therapy for Children: Considerations Regarding Brainstem Injury. Int J Radiat Oncol Biol Phys. 2018 05 01; 101(1):152-168. PMID: 29619963.
      View in: PubMed
    37. Wilke C, Grosshans D, Duman J, Brown P, Li J. Radiation-induced cognitive toxicity: pathophysiology and interventions to reduce toxicity in adults. Neuro Oncol. 2018 04 09; 20(5):597-607. PMID: 29045710.
      View in: PubMed
    38. Duman JG, Dinh J, Zhou W, Cham H, Mavratsas VC, Paveškovic M, Mulherkar S, McGovern SL, Tolias KF, Grosshans DR. Memantine prevents acute radiation-induced toxicities at hippocampal excitatory synapses. Neuro Oncol. 2018 04 09; 20(5):655-665. PMID: 29112734.
      View in: PubMed
    39. Vassiliev ON, Kry SF, Grosshans DR, Mohan R. Average stopping powers for electron and photon sources for radiobiological modeling and microdosimetric applications. Phys Med Biol. 2018 03 02; 63(5):055007. PMID: 29411712.
      View in: PubMed
    40. Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Erratum: "Monte Carlo simulations of 3 He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness" [Med. Phys. 43 (2), page range 761-776(2016)]. Med Phys. 2018 Mar; 45(3):1301. PMID: 29527699.
      View in: PubMed
    41. Guan F, Peeler C, Bronk L, Geng C, Taleei R, Randeniya S, Ge S, Mirkovic D, Grosshans D, Mohan R, Titt U. Erratum: "Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code" [Med. Phys. 42 (11), page range 6234-6247(2015)]. Med Phys. 2018 Mar; 45(3):1302. PMID: 29527697.
      View in: PubMed
    42. Yepes P, Adair A, Grosshans D, Mirkovic D, Poenisch F, Titt U, Wang Q, Mohan R. Comparison of Monte Carlo and analytical dose computations for intensity modulated proton therapy. Phys Med Biol. 2018 02 09; 63(4):045003. PMID: 29339570.
      View in: PubMed
    43. Ludmir EB, Paulino AC, Grosshans DR, McAleer MF, McGovern SL, Huh WW, Okcu MF, Harrell LM, Mahajan A. Regional Nodal Control for Head and Neck Alveolar Rhabdomyosarcoma. Int J Radiat Oncol Biol Phys. 2018 05 01; 101(1):169-176. PMID: 29477293.
      View in: PubMed
    44. Paulino AC, Mahajan A, Ye R, Grosshans DR, Fatih Okcu M, Su J, McAleer MF, McGovern S, Mangona VA, Chintagumpala M. Ototoxicity and cochlear sparing in children with medulloblastoma: Proton vs. photon radiotherapy. Radiother Oncol. 2018 07; 128(1):128-132. PMID: 29373195.
      View in: PubMed
    45. Bronk JK, Guha-Thakurta N, Allen PK, Mahajan A, Grosshans DR, McGovern SL. Analysis of pseudoprogression after proton or photon therapy of 99 patients with low grade and anaplastic glioma. Clin Transl Radiat Oncol. 2018 Feb; 9:30-34. PMID: 29594248.
      View in: PubMed
    46. Mohan R, Held KD, Story MD, Grosshans D, Capala J. Proceedings of the National Cancer Institute Workshop on Charged Particle Radiobiology. Int J Radiat Oncol Biol Phys. 2018 03 15; 100(4):816-831. PMID: 29485053.
      View in: PubMed
    47. Cao W, Khabazian A, Yepes PP, Lim G, Poenisch F, Grosshans DR, Mohan R. Linear energy transfer incorporated intensity modulated proton therapy optimization. Phys Med Biol. 2017 12 19; 63(1):015013. PMID: 29131808.
      View in: PubMed
    48. Wang X, Li Y, Zhang X, Li H, Miyazaki K, Fujimoto R, Akiyama H, Gillin MT, Poenisch F, Sahoo N, Grosshans D, Gunn B, Frank SJ, Wang P, Lang J, Hou Q, Zhu XR. Synchrotron-Based Pencil Beam Scanning Nozzle with an Integrated Mini-Ridge Filter: A Dosimetric Study to Optimize Treatment Delivery. Cancers (Basel). 2017 Dec 13; 9(12). PMID: 29236051.
      View in: PubMed
    49. Patel D, Bronk L, Guan F, Peeler CR, Brons S, Dokic I, Abdollahi A, Rittmüller C, Jäkel O, Grosshans D, Mohan R, Titt U. Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams. Med Phys. 2017 Nov; 44(11):6061-6073. PMID: 28880368.
      View in: PubMed
    50. Vassiliev ON, Grosshans DR, Mohan R. A new formalism for modelling parameters a and ß of the linear-quadratic model of cell survival for hadron therapy. Phys Med Biol. 2017 Oct 03; 62(20):8041-8059. PMID: 28832343.
      View in: PubMed
    51. Chun SG, Solberg TD, Grosshans DR, Nguyen QN, Simone CB, Mohan R, Liao Z, Hahn SM, Herman JM, Frank SJ. The Potential of Heavy-Ion Therapy to Improve Outcomes for Locally Advanced Non-Small Cell Lung Cancer. Front Oncol. 2017; 7:201. PMID: 28929085.
      View in: PubMed
    52. Raza SM, Gidley PW, Meis JM, Grosshans DR, Bell D, DeMonte F. Multimodality Treatment of Skull Base Chondrosarcomas: The Role of Histology Specific Treatment Protocols. Neurosurgery. 2017 Sep 01; 81(3):520-530. PMID: 28368506.
      View in: PubMed
    53. Mohan R, Peeler CR, Guan F, Bronk L, Cao W, Grosshans DR. Radiobiological issues in proton therapy. Acta Oncol. 2017 Nov; 56(11):1367-1373. PMID: 28826292.
      View in: PubMed
    54. Abolfath R, Peeler CR, Newpower M, Bronk L, Grosshans D, Mohan R. A model for relative biological effectiveness of therapeutic proton beams based on a global fit of cell survival data. Sci Rep. 2017 08 21; 7(1):8340. PMID: 28827691.
      View in: PubMed
    55. Antonini TN, Ris MD, Grosshans DR, Mahajan A, Okcu MF, Chintagumpala M, Paulino A, Child AE, Orobio J, Stancel HH, Kahalley LS. Attention, processing speed, and executive functioning in pediatric brain tumor survivors treated with proton beam radiation therapy. Radiother Oncol. 2017 07; 124(1):89-97. PMID: 28655455.
      View in: PubMed
    56. Grosshans DR, Mohan R, Gondi V, Shih HA, Mahajan A, Brown PD. The role of image-guided intensity modulated proton therapy in glioma. Neuro Oncol. 2017 04 01; 19(suppl_2):ii30-ii37. PMID: 28380636.
      View in: PubMed
    57. Hou P, Zhu KH, Park PC, Li H, Mahajan A, Grosshans DR. Proton Therapy for Juvenile Pilocytic Astrocytoma: Quantifying Treatment Responses by Magnetic Resonance Diffusion Tensor Imaging. Int J Part Ther. 2017; 3(3):414-420. PMID: 31772991.
      View in: PubMed
    58. Liao L, Lim GJ, Li Y, Yu J, Sahoo N, Li H, Gillin M, Zhu XR, Mahajan A, Frank SJ, Grosshans DR, Nguyen QN, Gomez D, Zhang X. Robust Optimization for Intensity Modulated Proton Therapy Plans with Multi-Isocenter Large Fields. Int J Part Ther. 2016; 3(2):305-311. PMID: 31772982.
      View in: PubMed
    59. Mohan R, Grosshans D. Proton therapy - Present and future. Adv Drug Deliv Rev. 2017 01 15; 109:26-44. PMID: 27919760.
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    60. Peeler CR, Mirkovic D, Titt U, Blanchard P, Gunther JR, Mahajan A, Mohan R, Grosshans DR. Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma. Radiother Oncol. 2016 12; 121(3):395-401. PMID: 27863964.
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    61. Greenfield BJ, Jaramillo S, Abboud M, Mahajan A, Paulino AC, McGovern S, McAleer MF, Chintagumpala M, Okcu MF, Khatua S, Su J, Grosshans DR. Outcomes for pediatric patients with central nervous system germ cell tumors treated with proton therapy. Clin Transl Radiat Oncol. 2016 Dec; 1:9-14. PMID: 29657988.
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    62. Wang X, Poenisch F, Sahoo N, Zhu RX, Lii M, Gillin MT, Li J, Grosshans D. Spot scanning proton therapy minimizes neutron dose in the setting of radiation therapy administered during pregnancy. J Appl Clin Med Phys. 2016 09 08; 17(5):366-376. PMID: 27685136.
      View in: PubMed
    63. Jiang S, Wang J, Li H, Liao L, Li Y, Wang X, Yang Y, Zhu RX, Sahoo N, Gillin MT, Hojo Y, Sun J, Chang JY, Liao Z, Grosshans D, Frank SJ, Zhang X. Novel Hybrid Scattering- and Scanning-Beam Proton Therapy Approach. Int J Part Ther. 2016; 3(1):37-50. PMID: 31772974.
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    64. Tucker SL, Liu A, Gomez D, Tang LL, Allen P, Yang J, Liao Z, Grosshans D. Impact of heart and lung dose on early survival in patients with non-small cell lung cancer treated with chemoradiation. Radiother Oncol. 2016 06; 119(3):495-500. PMID: 27189523.
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    65. Agarwal A, Thaker NG, Tawk B, Allen PK, Grosshans DR, Herzog CE, Gombos DS, Mahajan A. The Evolution of Radiation Therapy for Retinoblastoma: The MD Anderson Cancer Center Experience. Int J Part Ther. 2016 Mar; 2(4):490-498. PMID: 31772961.
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    66. Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Monte Carlo simulations of ³He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness. Med Phys. 2016 Feb; 43(2):761-76. PMID: 26843239.
      View in: PubMed
    67. Grosshans DR. Proton therapy for paediatric medulloblastoma. Lancet Oncol. 2016 Mar; 17(3):258-9. PMID: 26830376.
      View in: PubMed
    68. Kahalley LS, Ris MD, Grosshans DR, Okcu MF, Paulino AC, Chintagumpala M, Moore BD, Guffey D, Minard CG, Stancel HH, Mahajan A. Comparing Intelligence Quotient Change After Treatment With Proton Versus Photon Radiation Therapy for Pediatric Brain Tumors. J Clin Oncol. 2016 Apr 01; 34(10):1043-9. PMID: 26811522.
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    69. Owusu-Agyemang P, Popovich SM, Zavala AM, Grosshans DR, Van Meter A, Williams UU, Holmes AA, Arunkumar R, Rebello E, McAleer MF, Porche V, Mahajan A. A multi-institutional pilot survey of anesthesia practices during proton radiation therapy. Pract Radiat Oncol. 2016 May-Jun; 6(3):155-159. PMID: 26725965.
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    70. Guan F, Peeler C, Bronk L, Geng C, Taleei R, Randeniya S, Ge S, Mirkovic D, Grosshans D, Mohan R, Titt U. Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant4 Monte Carlo code. Med Phys. 2015 Nov; 42(11):6234-47. PMID: 26520716.
      View in: PubMed
    71. Munck af Rosenschold P, Engelholm SA, Brodin PN, Jørgensen M, Grosshans DR, Zhu RX, Palmer M, Crawford CN, Mahajan A. A Retrospective Evaluation of the Benefit of Referring Pediatric Cancer Patients to an External Proton Therapy Center. Pediatr Blood Cancer. 2016 Feb; 63(2):262-9. PMID: 26397177.
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    72. Grant SR, Grosshans DR, Bilton SD, Garcia JA, Amin M, Chambers MS, McGovern SL, McAleer MF, Morrison WH, Huh WW, Kupferman ME, Mahajan A. Proton versus conventional radiotherapy for pediatric salivary gland tumors: Acute toxicity and dosimetric characteristics. Radiother Oncol. 2015 Aug; 116(2):309-15. PMID: 26232128.
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    73. Guan F, Bronk L, Titt U, Lin SH, Mirkovic D, Kerr MD, Zhu XR, Dinh J, Sobieski M, Stephan C, Peeler CR, Taleei R, Mohan R, Grosshans DR. Spatial mapping of the biologic effectiveness of scanned particle beams: towards biologically optimized particle therapy. Sci Rep. 2015 May 18; 5:9850. PMID: 25984967.
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    74. Holliday EB, Mitra HS, Somerson JS, Rhines LD, Mahajan A, Brown PD, Grosshans DR. Postoperative proton therapy for chordomas and chondrosarcomas of the spine: adjuvant versus salvage radiation therapy. Spine (Phila Pa 1976). 2015 Apr 15; 40(8):544-9. PMID: 25627289.
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    75. Day J, Zienius K, Gehring K, Grosshans D, Taphoorn M, Grant R, Li J, Brown PD. Interventions for preventing and ameliorating cognitive deficits in adults treated with cranial irradiation. Cochrane Database Syst Rev. 2014 Dec 18; (12):CD011335. PMID: 25519950.
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    76. McGovern SL, Grosshans D, Mahajan A. Embryonal brain tumors. Cancer J. 2014 Nov-Dec; 20(6):397-402. PMID: 25415685.
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    77. Ladra MM, Szymonifka JD, Mahajan A, Friedmann AM, Yong Yeap B, Goebel CP, MacDonald SM, Grosshans DR, Rodriguez-Galindo C, Marcus KJ, Tarbell NJ, Yock TI. Preliminary results of a phase II trial of proton radiotherapy for pediatric rhabdomyosarcoma. J Clin Oncol. 2014 Nov 20; 32(33):3762-70. PMID: 25332253.
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    78. Ladra MM, Edgington SK, Mahajan A, Grosshans D, Szymonifka J, Khan F, Moteabbed M, Friedmann AM, MacDonald SM, Tarbell NJ, Yock TI. A dosimetric comparison of proton and intensity modulated radiation therapy in pediatric rhabdomyosarcoma patients enrolled on a prospective phase II proton study. Radiother Oncol. 2014 Oct; 113(1):77-83. PMID: 25443861.
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    79. McGovern SL, Okcu MF, Munsell MF, Kumbalasseriyil N, Grosshans DR, McAleer MF, Chintagumpala M, Khatua S, Mahajan A. Outcomes and acute toxicities of proton therapy for pediatric atypical teratoid/rhabdoid tumor of the central nervous system. Int J Radiat Oncol Biol Phys. 2014 Dec 01; 90(5):1143-52. PMID: 25311260.
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    80. Gomez DR, Yusuf SW, Munsell MF, Welsh JW, Liao Z, Lin SH, Pan HY, Chang JY, Komaki R, Cox JD, McAleer MF, Grosshans DR. Prospective exploratory analysis of cardiac biomarkers and electrocardiogram abnormalities in patients receiving thoracic radiation therapy with high-dose heart exposure. J Thorac Oncol. 2014 Oct; 9(10):1554-60. PMID: 25521400.
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    81. Grosshans DR, Zhu XR, Melancon A, Allen PK, Poenisch F, Palmer M, McAleer MF, McGovern SL, Gillin M, DeMonte F, Chang EL, Brown PD, Mahajan A. Spot scanning proton therapy for malignancies of the base of skull: treatment planning, acute toxicities, and preliminary clinical outcomes. Int J Radiat Oncol Biol Phys. 2014 Nov 01; 90(3):540-6. PMID: 25304948.
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    82. Zhu XR, Poenisch F, Li H, Zhang X, Sahoo N, Wu RY, Li X, Lee AK, Chang EL, Choi S, Pugh T, Frank SJ, Gillin MT, Mahajan A, Grosshans DR. A single-field integrated boost treatment planning technique for spot scanning proton therapy. Radiat Oncol. 2014 Sep 11; 9:202. PMID: 25212571.
      View in: PubMed
    83. Stoker JB, Grant J, Zhu XR, Pidikiti R, Mahajan A, Grosshans DR. Intensity modulated proton therapy for craniospinal irradiation: organ-at-risk exposure and a low-gradient junctioning technique. Int J Radiat Oncol Biol Phys. 2014 Nov 01; 90(3):637-44. PMID: 25194667.
      View in: PubMed
    84. LeRoux LG, Bredow S, Grosshans D, Schellingerhout D. Molecular imaging detects impairment in the retrograde axonal transport mechanism after radiation-induced spinal cord injury. Mol Imaging Biol. 2014 Aug; 16(4):504-10. PMID: 24395625.
      View in: PubMed
    85. Bishop AJ, Greenfield B, Mahajan A, Paulino AC, Okcu MF, Allen PK, Chintagumpala M, Kahalley LS, McAleer MF, McGovern SL, Whitehead WE, Grosshans DR. Proton beam therapy versus conformal photon radiation therapy for childhood craniopharyngioma: multi-institutional analysis of outcomes, cyst dynamics, and toxicity. Int J Radiat Oncol Biol Phys. 2014 Oct 01; 90(2):354-61. PMID: 25052561.
      View in: PubMed
    86. Shao Y, Sun X, Lou K, Zhu XR, Mirkovic D, Poenisch F, Grosshans D. In-beam PET imaging for on-line adaptive proton therapy: an initial phantom study. Phys Med Biol. 2014 Jul 07; 59(13):3373-88. PMID: 24874943.
      View in: PubMed
    87. Owusu-Agyemang P, Grosshans D, Arunkumar R, Rebello E, Popovich S, Zavala A, Williams C, Ruiz J, Hernandez M, Mahajan A, Porche V. Non-invasive anesthesia for children undergoing proton radiation therapy. Radiother Oncol. 2014 Apr; 111(1):30-4. PMID: 24560754.
      View in: PubMed
    88. Liu W, Mohan R, Park P, Liu Z, Li H, Li X, Li Y, Wu R, Sahoo N, Dong L, Zhu XR, Grosshans DR. Dosimetric benefits of robust treatment planning for intensity modulated proton therapy for base-of-skull cancers. Pract Radiat Oncol. 2014 Nov-Dec; 4(6):384-91. PMID: 25407859.
      View in: PubMed
    89. Dinh J, Stoker J, Georges RH, Sahoo N, Zhu XR, Rath S, Mahajan A, Grosshans DR. Comparison of proton therapy techniques for treatment of the whole brain as a component of craniospinal radiation. Radiat Oncol. 2013 Dec 17; 8:289. PMID: 24344645.
      View in: PubMed
    90. Barney CL, Brown AP, Grosshans DR, McAleer MF, de Groot JF, Puduvalli V, Tucker SL, Crawford CN, Gilbert MR, Brown PD, Mahajan A. Technique, outcomes, and acute toxicities in adults treated with proton beam craniospinal irradiation. Neuro Oncol. 2014 Jan; 16(2):303-9. PMID: 24311638.
      View in: PubMed
    91. Tucker SL, Liao Z, Dinh J, Bian SX, Mohan R, Martel MK, Grosshans DR. Is there an impact of heart exposure on the incidence of radiation pneumonitis? Analysis of data from a large clinical cohort. Acta Oncol. 2014 May; 53(5):590-6. PMID: 23992110.
      View in: PubMed
    92. Brown AP, Barney CL, Grosshans DR, McAleer MF, de Groot JF, Puduvalli VK, Tucker SL, Crawford CN, Khan M, Khatua S, Gilbert MR, Brown PD, Mahajan A. Proton beam craniospinal irradiation reduces acute toxicity for adults with medulloblastoma. Int J Radiat Oncol Biol Phys. 2013 Jun 01; 86(2):277-84. PMID: 23433794.
      View in: PubMed
    93. Bian SX, McAleer MF, Vats TS, Mahajan A, Grosshans DR. Pilocytic astrocytoma with leptomeningeal dissemination. Childs Nerv Syst. 2013 Mar; 29(3):441-50. PMID: 23207974.
      View in: PubMed
    94. Sharp H, Grosshans D, Kadia T, Dabaja BS. Cutaneous graft-versus-host disease after proton-based craniospinal irradiation for recurrent Philadelphia-positive acute lymphoblastic leukaemia. BMJ Case Rep. 2012 Jul 11; 2012. PMID: 22787181.
      View in: PubMed
    95. Wu PH, Coultrap S, Pinnix C, Davies KD, Tailor R, Ang KK, Browning MD, Grosshans DR. Radiation induces acute alterations in neuronal function. PLoS One. 2012; 7(5):e37677. PMID: 22662188.
      View in: PubMed
    96. Amsbaugh MJ, Zhu XR, Palmer M, Poenisch F, McAleer MF, Mahajan A, Grosshans DR. Spot scanning proton therapy for craniopharyngioma. Pract Radiat Oncol. 2012 Oct-Dec; 2(4):314-318. PMID: 24674170.
      View in: PubMed
    97. Amsbaugh MJ, Grosshans DR, McAleer MF, Zhu R, Wages C, Crawford CN, Palmer M, De Gracia B, Woo S, Mahajan A. Proton therapy for spinal ependymomas: planning, acute toxicities, and preliminary outcomes. Int J Radiat Oncol Biol Phys. 2012 Aug 01; 83(5):1419-24. PMID: 22245209.
      View in: PubMed
    98. Boehling NS, Grosshans DR, Allen PK, McAleer MF, Burton AW, Azeem S, Rhines LD, Chang EL. Vertebral compression fracture risk after stereotactic body radiotherapy for spinal metastases. J Neurosurg Spine. 2012 Apr; 16(4):379-86. PMID: 22225488.
      View in: PubMed
    99. Pinnix CC, Fontanilla HP, Hayes-Jordan A, Subbiah V, Bilton SD, Chang EL, Grosshans DR, McAleer MF, Sulman EP, Woo SY, Anderson P, Green HL, Mahajan A. Whole abdominopelvic intensity-modulated radiation therapy for desmoplastic small round cell tumor after surgery. Int J Radiat Oncol Biol Phys. 2012 May 01; 83(1):317-26. PMID: 22104361.
      View in: PubMed
    100. Grosshans D, Boehling NS, Palmer M, Spicer C, Erice R, Cox JD, Komaki R, Chang JY. Improving cardiac dosimetry: Alternative beam arrangements for intensity modulated radiation therapy planning in patients with carcinoma of the distal esophagus. Pract Radiat Oncol. 2012 Jan-Mar; 2(1):41-5. PMID: 24674035.
      View in: PubMed
    101. Moeller BJ, Chintagumpala M, Philip JJ, Grosshans DR, McAleer MF, Woo SY, Gidley PW, Vats TS, Mahajan A. Low early ototoxicity rates for pediatric medulloblastoma patients treated with proton radiotherapy. Radiat Oncol. 2011 Jun 02; 6:58. PMID: 21635776.
      View in: PubMed
    102. Boehling NS, Grosshans DR, Bluett JB, Palmer MT, Song X, Amos RA, Sahoo N, Meyer JJ, Mahajan A, Woo SY. Dosimetric comparison of three-dimensional conformal proton radiotherapy, intensity-modulated proton therapy, and intensity-modulated radiotherapy for treatment of pediatric craniopharyngiomas. Int J Radiat Oncol Biol Phys. 2012 Feb 01; 82(2):643-52. PMID: 21277111.
      View in: PubMed
    103. Grosshans DR, Meyers CA, Allen PK, Davenport SD, Komaki R. Neurocognitive function in patients with small cell lung cancer : effect of prophylactic cranial irradiation. Cancer. 2008 Feb 01; 112(3):589-95. PMID: 18098269.
      View in: PubMed
    104. Hellier JL, Grosshans DR, Coultrap SJ, Jones JP, Dobelis P, Browning MD, Staley KJ. NMDA receptor trafficking at recurrent synapses stabilizes the state of the CA3 network. J Neurophysiol. 2007 Nov; 98(5):2818-26. PMID: 17728388.
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    105. Alvestad RM, Grosshans DR, Coultrap SJ, Nakazawa T, Yamamoto T, Browning MD. Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function. J Biol Chem. 2003 Mar 28; 278(13):11020-5. PMID: 12536146.
      View in: PubMed
    106. Grosshans DR, Clayton DA, Coultrap SJ, Browning MD. Analysis of glutamate receptor surface expression in acute hippocampal slices. Sci STKE. 2002 Jun 18; 2002(137):pl8. PMID: 12072555.
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    107. Clayton DA, Grosshans DR, Browning MD. Aging and surface expression of hippocampal NMDA receptors. J Biol Chem. 2002 Apr 26; 277(17):14367-9. PMID: 11891215.
      View in: PubMed
    108. Grosshans DR, Clayton DA, Coultrap SJ, Browning MD. LTP leads to rapid surface expression of NMDA but not AMPA receptors in adult rat CA1. Nat Neurosci. 2002 Jan; 5(1):27-33. PMID: 11740502.
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    109. Grosshans DR, Browning MD. Protein kinase C activation induces tyrosine phosphorylation of the NR2A and NR2B subunits of the NMDA receptor. J Neurochem. 2001 Feb; 76(3):737-44. PMID: 11158244.
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    110. Oh JJ, Grosshans DR, Wong SG, Slamon DJ. Identification of differentially expressed genes associated with HER-2/neu overexpression in human breast cancer cells. Nucleic Acids Res. 1999 Oct 15; 27(20):4008-17. PMID: 10497265.
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    111. Péterfy M, Gyuris T, Grosshans D, Cuaresma CC, Takács L. Cloning and characterization of cDNAs and the gene encoding the mouse platelet-activating factor acetylhydrolase Ib alpha subunit/lissencephaly-1 protein. Genomics. 1998 Jan 15; 47(2):200-6. PMID: 9479492.
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    112. Chang Ms, McNinch J, Elias C, Manthey CL, Grosshans D, Meng T, Boone T, Andrew DP. Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes. J Biol Chem. 1997 Oct 03; 272(40):25229-37. PMID: 9312138.
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    113. Wilson CA, Payton MN, Elliott GS, Buaas FW, Cajulis EE, Grosshans D, Ramos L, Reese DM, Slamon DJ, Calzone FJ. Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b. Oncogene. 1997 Jan 09; 14(1):1-16. PMID: 9010228.
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    114. Spot scanning proton therapy for craniopharyngioma. Practical Radiation Oncology. 2:314-318.
    115. Spatial mapping of the biologic effectiveness of scanned particle beams. Scientific Reports. 5.
    116. Spot scanning proton therapy minimizes neutron dose in the setting of radiation therapy administered during pregnancy. Journal of Applied Clinical Medical Physics. 17:366-376.
    117. Catechol-o-methyltransferase genotype modulates cancer treatment-related cognitive deficits in breast cancer survivors. Breast Diseases. 22:411-412.
    118. A multi-institutional pilot survey of anesthesia practices during proton radiation therapy. Practical Radiation Oncology.
    119. Particle therapy for central nervous system tumors in pediatric and adult patients. Translational Cancer Research. 1:137-149.
    120. Comparing intelligence quotient change after treatment with proton versus photon radiation therapy for pediatric brain tumors. Journal of Clinical Oncology. 34:1043-1049.
    121. Proton therapy - Present and future. Advanced Drug Delivery Reviews.
    122. Cutaneous graft-versus-host disease after proton-based craniospinal irradiation for recurrent Philadelphia-positive acute lymphoblastic leukaemia. BMJ Case Reports.
    123. Clinical evidence of variable proton biological effectiveness in pediatric patients treated for ependymoma. Radiotherapy and Oncology. 121:395-401.
    124. Proton therapy for paediatric medulloblastoma. The Lancet Oncology. 17:258-259.
    125. Analysis of the track- and dose-averaged LET and LET spectra in proton therapy using the geant 4 Monte Carlo code. Medical Physics. 42:6234-6247.
    126. Impact of heart and lung dose on early survival in patients with non-small cell lung cancer treated with chemoradiation. Radiotherapy and Oncology.
    127. Proton versus conventional radiotherapy for pediatric salivary gland tumors. Radiotherapy and Oncology.
    128. Improving cardiac dosimetry. Practical Radiation Oncology. 2:41-45.
    129. Monte Carlo simulations of 3He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness. Medical Physics. 43:761-776.
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