Dr. Fisher has focused his entire career on pancreatic cancer and is internationally known for his clinical work as a pancreatic surgeon, basic science research, and clinical research in pancreatic cancer. As Director of the Elkins Pancreas Center at Baylor College of Medicine (BCM) he has developed and coordinates all of the clinical care for a large pancreatic cancer patient population as well as all of the basic science and clinical research related to pancreatic cancer being performed at BCM.
Dr. Fisher established a pancreatic cancer tissue resource and an extensive clinical database which serve as a vital resource for research. Dr. Fisher’s lab has studied the influence of gastrointestinal hormones, particularly somatostatin and its receptors, on pancreatic cancer growth, and the relationship between diabetes and pancreatic cancer.
Dr. Fisher has also collaborated on projects examining the role PDX-1 as an oncogene, gene therapy, oncolytic virotherapy, vaccination with virus-like particles, and adoptive immunotherapy for pancreatic cancer. He is also actively collaborating with investigators in the Human Genome Sequencing Center at BCM on studies sequencing the genome of pancreatic cancer. Dr. Fisher leads a team of research clinicians dedicated to translating discoveries from the bench to the bedside and has served as principal investigator on more than 15 clinical trials for patients with pancreatic cancer.