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WILLIAM E COHN

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
DivisionSurgery-Transplant Division
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    Dr. William E. Cohn is one of the leaders of the team of experts developing a total artificial heart that will deliver blood by means of continuous flow rather than pulsation. This research has grant support from the National Heart, Lung, and Blood Institute; the John S. Dunn Research Foundation; the Alexander Family Trust; and the McIngvale family Trust. This new artificial heart is smaller, less expensive, and predicted to be more reliable than previous generations of artificial hearts.

    William E. Cohn currently has 80 active or pending patents for his inventions and is the founder or co-founder of five venture-backed life science startups.

    In addition, Dr. Cohn is a venture partner at Santé Health Ventures, a venture capital firm focused on capitalizing early-stage life science technology.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kurihara C, Cohn WE, Kawabori M, Sugiura T, Civitello AB, Morgan JA. Long-Term Continuous-Flow Left Ventricular Assist Device Support After Left Ventricular Outflow Tract Closure. ASAIO J. 2019 Aug; 65(6):558-564. PMID: 30074962.
      View in: PubMed
    2. Demirozu ZT, Critsinelis A, Cohn WE, Radovancevic R, Ho J, Hernandez R, Morgan JA, Frazier OH. Experience with the HeartMate II Left Ventricular Assist Device in Patients Older than 60 Years. Heart Surg Forum. 2019 03 08; 22(2):E124-E130. PMID: 31013222.
      View in: PubMed
    3. Hord EC, Bolch CM, Tuzun E, Cohn WE, Leschinsky B, Criscione JC. Evaluation of the CorInnova Heart Assist Device in an Acute Heart Failure Model. J Cardiovasc Transl Res. 2019 Apr; 12(2):155-163. PMID: 30604307.
      View in: PubMed
    4. Hakim J, Smith PA, Singh M, Han Z, Raghunathan R, Wyman O, Guffey D, Larin KV, Cohn W, Dietrich JE. Can We Improve Vaginal Tissue Healing Using Customized Devices: 3D Printing and Biomechanical Changes in Vaginal Tissue. Gynecol Obstet Invest. 2019; 84(2):145-153. PMID: 30269139.
      View in: PubMed
    5. Smith PA, Wang Y, Bieritz SA, Sampaio LC, Cohn WE, Metcalfe RW, Frazier OH. Design Method Using Statistical Models for Miniature Left Ventricular Assist Device Hydraulics. Ann Biomed Eng. 2019 Jan; 47(1):126-137. PMID: 30267173.
      View in: PubMed
    6. Smith PA, Wang Y, Bieritz SA, Conger JL, Sampaio LC, Cohn WE, Frazier OH. In Vivo Feasibility Study of an Intra-Atrial Blood Pump for Partial Support of the Left Ventricle. Conf Proc IEEE Eng Med Biol Soc. 2018 07; 2018:4520-4523. PMID: 30441356.
      View in: PubMed
    7. Smith PA, Wang Y, Bieritz SA, Sampaio LC, Metcalfe RW, Cohn WE, Frazier OH. Hemodynamic Evaluation of an Intra-Atrial Blood Pump on a Pulsatile Mock Circulatory Loop. Conf Proc IEEE Eng Med Biol Soc. 2018 07; 2018:4508-4511. PMID: 30441353.
      View in: PubMed
    8. Ng BC, Kleinheyer M, Smith PA, Timms D, Cohn WE, Lim E. Pulsatile operation of a continuous-flow right ventricular assist device (RVAD) to improve vascular pulsatility. PLoS One. 2018; 13(4):e0195975. PMID: 29677212.
      View in: PubMed
    9. Baldwin ACW, Cohn WE, Morgan JA, Frazier OH. Long-Term Continuous-Flow Biventricular Support in a 63-Year-Old Woman. Tex Heart Inst J. 2018 04; 45(2):110-112. PMID: 29844746.
      View in: PubMed
    10. Kurihara C, Kawabori M, Sugiura T, Critsinelis AC, Wang S, Cohn WE, Civitello AB, Frazier OH, Morgan JA. Bridging to a Long-Term Ventricular Assist Device With Short-Term Mechanical Circulatory Support. Artif Organs. 2018 Jun; 42(6):589-596. PMID: 29473181.
      View in: PubMed
    11. Smith PA, Wang Y, Metcalfe RW, Sampaio LC, Timms DL, Cohn WE, Frazier OH. Preliminary design of the internal geometry in a minimally invasive left ventricular assist device under pulsatile-flow conditions. Int J Artif Organs. 2018 Mar; 41(3):144-151. PMID: 29546808.
      View in: PubMed
    12. Kawabori M, Kurihara C, Sugiura T, Cohn WE, Civitello AB, Frazier OH, Morgan JA. Continuous-Flow Left Ventricular Assist Device Implantation in Patients With a Small Left Ventricle. Ann Thorac Surg. 2018 03; 105(3):799-806. PMID: 29290308.
      View in: PubMed
    13. Schmitto JD, Hanke JS, Dogan G, Tessmann R, Jeevanandem V, Cohn WE, Frazier OH, Haverich A. First Implantation of a Novel Left Ventricular Assist Device: The ReliantHeart aVAD. Ann Thorac Surg. 2017 Oct; 104(4):e311-e313. PMID: 28935323.
      View in: PubMed
    14. Baldwin ACW, Gemmato CJ, Sandoval E, Cohn WE, Morgan JA, Frazier OH. Tolerance of Sustained Ventricular Fibrillation During Continuous-Flow Left Ventricular Assist Device Support. Tex Heart Inst J. 2017 Oct; 44(5):357-360. PMID: 29259511.
      View in: PubMed
    15. Smith RE, Smith PA, Cohn WE. Predicting the Dimensions of an Intracardiac Partial-Assist Pump for Percutaneous Delivery by Analytical and Numerical Methods. Cardiovasc Eng Technol. 2017 12; 8(4):453-464. PMID: 28940163.
      View in: PubMed
    16. Wang Y, Logan TG, Smith PA, Hsu PL, Cohn WE, Xu L, McMahon RA. Systematic Design of a Magnetically Levitated Brushless DC Motor for a Reversible Rotary Intra-Aortic Blood Pump. Artif Organs. 2017 Oct; 41(10):923-933. PMID: 28929512.
      View in: PubMed
    17. Smith PA, De-Sciscio P, Sampaio LC, Cohn WE, McMahon RA. Replication of pressure-volume loop with controllable ESPVR and EDPVR curves on a personalized mock circulatory loop based on elastance function. Conf Proc IEEE Eng Med Biol Soc. 2017 07; 2017:1282-1286. PMID: 29060110.
      View in: PubMed
    18. Baldwin ACW, Sandoval E, Cohn WE, Mallidi HR, Morgan JA, Frazier OH. Nonidentical Continuous-Flow Devices For Biventricular Support. Tex Heart Inst J. 2017 Apr; 44(2):141-143. PMID: 28461802.
      View in: PubMed
    19. Kawabori M, Kurihara C, Miller Y, Heck KA, Bogaev RC, Civitello AB, Cohn WE, Frazier OH, Morgan JA. Total artificial heart implantation for biventricular failure due to eosinophilic myocarditis. J Artif Organs. 2017 Sep; 20(3):266-269. PMID: 28349221.
      View in: PubMed
    20. Adachi I, Burki S, Horne D, Costas GG, Spangler T, Jarvik R, Teal J, Baldwin JT, Dasse K, Massicotte MP, Conger J, Cohn WE, Fraser CD. The miniaturized pediatric continuous-flow device: Preclinical assessment in the chronic sheep model. J Thorac Cardiovasc Surg. 2017 07; 154(1):291-300. PMID: 28495065.
      View in: PubMed
    21. Kawabori M, Kurihara C, Cohn WE, Civitello AB, Frazier OH, Morgan JA. Perforation of a HeartMate II outflow graft. J Card Surg. 2017 Mar; 32(3):233-234. PMID: 28247472.
      View in: PubMed
    22. Conger JL, Grace BW, Van Noy KL, Handy KM, Costas GG, Rodriguez-Sierra CA, Trejo A, Pinzon J, Cohn WE. In Vivo Evaluation of a Pneumatic Extracorporeal Ventricular Assist Device for up to 90 Day Support. ASAIO J. 2016 Nov/Dec; 62(6):697-703. PMID: 27442861.
      View in: PubMed
    23. Kleinheyer M, Timms DL, Tansley GD, Nestler F, Greatrex NA, Frazier OH, Cohn WE. Rapid Speed Modulation of a Rotary Total Artificial Heart Impeller. Artif Organs. 2016 Sep; 40(9):824-33. PMID: 27645393.
      View in: PubMed
    24. Ng BC, Smith PA, Nestler F, Timms D, Cohn WE, Lim E. Application of Adaptive Starling-Like Controller to Total Artificial Heart Using Dual Rotary Blood Pumps. Ann Biomed Eng. 2017 03; 45(3):567-579. PMID: 27543069.
      View in: PubMed
    25. Goerlich CE, Frazier OH, Cohn WE. Previous challenges and current progress-the use of total artificial hearts in patients with end-stage heart failure. Expert Rev Cardiovasc Ther. 2016 10; 14(10):1095-8. PMID: 27624221.
      View in: PubMed
    26. Baldwin AC, Mallidi HR, Baldwin JC, Sandoval E, Cohn WE, Frazier OH, Singh SK. Through the Looking Glass: Real-Time Video Using 'Smart' Technology Provides Enhanced Intraoperative Logistics. World J Surg. 2016 Jan; 40(1):242-4. PMID: 26316114.
      View in: PubMed
    27. Patel M, Rojas F, Shabari FR, Simpson L, Cohn W, Frazier OH, Mallidi H, Cheng J, Mathuria N. Safety and Feasibility of Open Chest Epicardial Mapping and Ablation of Ventricular Tachycardia During the Period of Left Ventricular Assist Device Implantation. J Cardiovasc Electrophysiol. 2016 Jan; 27(1):95-101. PMID: 26377813.
      View in: PubMed
    28. Anand J, Singh SK, Antoun DG, Cohn WE, Frazier OH, Mallidi HR. Durable Mechanical Circulatory Support versus Organ Transplantation: Past, Present, and Future. Biomed Res Int. 2015; 2015:849571. PMID: 26583140.
      View in: PubMed
    29. Boyle EM, Gillinov AM, Cohn WE, Ley SJ, Fischlein T, Perrault LP. Retained Blood Syndrome After Cardiac Surgery: A New Look at an Old Problem. Innovations (Phila). 2015 Sep-Oct; 10(5):296-303. PMID: 26575376.
      View in: PubMed
    30. Baldwin AC, Sandoval E, Letsou GV, Mallidi HR, Cohn WE, Frazier OH. Surgical approach to continuous-flow left ventricular assist device explantation: A comparison of outcomes. J Thorac Cardiovasc Surg. 2016 Jan; 151(1):192-8. PMID: 26344685.
      View in: PubMed
    31. Feng J, Cohn WE, Parnis SM, Sodha NR, Clements RT, Sellke N, Frazier OH, Sellke FW. New continuous-flow total artificial heart and vascular permeability. J Surg Res. 2015 Dec; 199(2):296-305. PMID: 26188957.
      View in: PubMed
    32. Cohn WE, Timms DL, Frazier OH. Total artificial hearts: past, present, and future. Nat Rev Cardiol. 2015 Oct; 12(10):609-17. PMID: 26031698.
      View in: PubMed
    33. Rajan DK, Ebner A, Desai SB, Rios JM, Cohn WE. Percutaneous creation of an arteriovenous fistula for hemodialysis access. J Vasc Interv Radiol. 2015 Apr; 26(4):484-90. PMID: 25805537.
      View in: PubMed
    34. Skorpil J, Paraforos A, Mandak J, Cohn WE, Hajek T, Friedrich I. Effective and rapid sealing of coronary, aortic and atrial suture lines †. Interact Cardiovasc Thorac Surg. 2015 Jun; 20(6):720-4; discussion 724. PMID: 25810290.
      View in: PubMed
    35. Frazier OH, Baldwin AC, Demirozu ZT, Segura AM, Hernandez R, Taegtmeyer H, Mallidi H, Cohn WE. Ventricular reconditioning and pump explantation in patients supported by continuous-flow left ventricular assist devices. J Heart Lung Transplant. 2015 Jun; 34(6):766-72. PMID: 25447571.
      View in: PubMed
    36. Anand J, Singh SK, Hernández R, Parnis SM, Civitello AB, Cohn WE, Mallidi HR. Continuous-flow ventricular assist device exchange is safe and effective in prolonging support time in patients with end-stage heart failure. J Thorac Cardiovasc Surg. 2015 Jan; 149(1):267-75, 278.e1. PMID: 25312232.
      View in: PubMed
    37. Nestler F, Bradley AP, Wilson SJ, Timms DL, Frazier OH, Cohn WE. A hybrid mock circulation loop for a total artificial heart. Artif Organs. 2014 Sep; 38(9):775-82. PMID: 25234760.
      View in: PubMed
    38. Gregoric ID, Radovancevic R, Patel M, Fenik Y, Cohn WE, Frazier OH. Use of sealed grafts in the HeartMate II left ventricular assist device inflow and outflow conduits. ASAIO J. 2014 May-Jun; 60(3):300-3. PMID: 24618753.
      View in: PubMed
    39. Mallidi HR, Anand J, Cohn WE. State of the art of mechanical circulatory support. Tex Heart Inst J. 2014 Apr; 41(2):115-20. PMID: 24808767.
      View in: PubMed
    40. Demirozu ZT, Hernandez R, Mallidi HR, Singh SK, Radovancevic R, Segura AM, Etheridge WB, Cohn WE, Frazier OH. HeartMate II left ventricular assist device implantation in patients with advanced hepatic dysfunction. J Card Surg. 2014 May; 29(3):419-23. PMID: 24641429.
      View in: PubMed
    41. Cohn WE, Handy KM, Parnis SM, Conger JL, Winkler JA, Frazier OH. Eight-year experience with a continuous-flow total artificial heart in calves. ASAIO J. 2014 Jan-Feb; 60(1):25-30. PMID: 24281122.
      View in: PubMed
    42. Kleinheyer M, Timms DL, Greatrex NA, Masuzawa T, Frazier OH, Cohn WE. Pulsatile operation of the BiVACOR TAH - Motor design, control and hemodynamics. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:5659-62. PMID: 25571279.
      View in: PubMed
    43. Love HC, Timms DL, Nestler F, Frazier OH, Cohn WE. A mock circulatory loop for designing and evaluating total artificial hearts. Conf Proc IEEE Eng Med Biol Soc. 2014; 2014:5667-70. PMID: 25571281.
      View in: PubMed
    44. Cohn WE, Winkler JA, Parnis S, Costas GG, Beathard S, Conger J, Frazier OH. Ninety-day survival of a calf implanted with a continuous-flow total artificial heart. ASAIO J. 2014 Jan-Feb; 60(1):15-8. PMID: 24281121.
      View in: PubMed
    45. Cohn WE, Mallidi HR, Frazier OH. Safe, effective off-pump sternal sparing approach for HeartMate II exchange. Ann Thorac Surg. 2013 Dec; 96(6):2259-61. PMID: 24296208.
      View in: PubMed
    46. Marcano J, Campos K, Rodriguez V, Handy K, Brewer MA, Cohn WE. Intrapericardial delivery of amiodarone rapidly achieves therapeutic levels in the atrium. Heart Surg Forum. 2013 Oct; 16(5):E279-86. PMID: 24364084.
      View in: PubMed
    47. Sarsam SH, Meyers DE, Civitello AB, Agunanne EE, Odegaard P, Cohn WE, Frazier OH. Trauma in patients with continuous-flow left ventricular assist devices. Am J Cardiol. 2013 Nov 01; 112(9):1520-2. PMID: 23993120.
      View in: PubMed
    48. Shabari FR, George J, Cuchiara MP, Langsner RJ, Heuring JJ, Cohn WE, Hertzog BA, Delgado R. Improved hemodynamics with a novel miniaturized intra-aortic axial flow pump in a porcine model of acute left ventricular dysfunction. ASAIO J. 2013 May-Jun; 59(3):240-5. PMID: 23644610.
      View in: PubMed
    49. Gregory SD, Loechel N, Pearcy MJ, Fraser J, Parnis S, Cohn WE, Timms D. Anatomic fitting of total artificial hearts for in vivo evaluation. Artif Organs. 2013 Aug; 37(8):735-41. PMID: 23461712.
      View in: PubMed
    50. Dutt-Ballerstadt R, Evans C, Pillai AP, Gowda A, McNichols R, Rios J, Cohn W. Acute in vivo performance evaluation of the fluorescence affinity sensor in the intravascular and interstitial space in Swine. J Diabetes Sci Technol. 2013 Jan 01; 7(1):35-44. PMID: 23439158.
      View in: PubMed
    51. Mazzitelli D, Nöbauer C, Rankin JS, Badiu CC, Krane M, Crooke PS, Cohn WE, Opitz A, Schreiber C, Lange R. Early results after implantation of a new geometric annuloplasty ring for aortic valve repair. Ann Thorac Surg. 2013 Jan; 95(1):94-7. PMID: 23063198.
      View in: PubMed
    52. Akay MH, Gregoric I, Cohn WE, Frazier OH. HeartMate-II left ventricular assist device infections resulting from gastrointestinal-tract fistulas. J Card Surg. 2012 Sep; 27(5):643-5. PMID: 22978845.
      View in: PubMed
    53. Gonzalez-Stawinski GV, Mountis MM, Cohn WE, Frazier OH. Inflow graft interruption as a simple method for left ventricular assist device removal after successful bridge to recovery. J Card Surg. 2012 May; 27(3):397-9. PMID: 22507259.
      View in: PubMed
    54. Tuzun E, Winkler JA, Contreras AL, Sacristan E, Cohn WE. In vivo performance evaluation of the innovamedica pneumatic ventricular assist device. ASAIO J. 2012 Mar-Apr; 58(2):98-102. PMID: 22236625.
      View in: PubMed
    55. Rankin JS, Conger JL, Tuzun E, Winkler JA, Harms KM, Beavan LA, Fossum T, Cohn WE. In vivo testing of an intra-annular aortic valve annuloplasty ring in a chronic calf model. Eur J Cardiothorac Surg. 2012 Jul; 42(1):149-54. PMID: 22362620.
      View in: PubMed
    56. Frazier OH, Cohn WE. Continuous-flow total heart replacement device implanted in a 55-year-old man with end-stage heart failure and severe amyloidosis. Tex Heart Inst J. 2012; 39(4):542-6. PMID: 22949774.
      View in: PubMed
    57. Akay MH, Gregoric ID, Radovancevic R, Cohn WE, Frazier OH. Timely use of a CentriMag heart assist device improves survival in postcardiotomy cardiogenic shock. J Card Surg. 2011 Sep; 26(5):548-52. PMID: 21951040.
      View in: PubMed
    58. Tuzun E, Parnis S, Rios J, Winkler JA, Cohn WE. Stent treatment of inferior vena cava compression in an ovine with a total artificial heart. Artif Organs. 2011 Jul; 35(7):E161-3. PMID: 21615430.
      View in: PubMed
    59. Rankin JS, Beavan LA, Cohn WE. Technique for aortic valve annuloplasty using an intra-annular "hemispherical" frame. J Thorac Cardiovasc Surg. 2011 Oct; 142(4):933-6. PMID: 21377696.
      View in: PubMed
    60. Cohn WE, Frazier OH. The sandwich plug technique: simple, effective, and rapid closure of a mechanical aortic valve prosthesis at left ventricular assist device implantation. J Thorac Cardiovasc Surg. 2011 Aug; 142(2):455-7. PMID: 21277593.
      View in: PubMed
    61. Gregoric ID, Cohn WE, Frazier OH. Diaphragmatic implantation of the HeartWare ventricular assist device. J Heart Lung Transplant. 2011 Apr; 30(4):467-70. PMID: 21211994.
      View in: PubMed
    62. Sacristán E, Tuzun E, Winkler JA, Contreras AL, Cohn WE. In vivo performance evaluation of the Innovamedica pneumatic ventricular assist device. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:1217-20. PMID: 22254535.
      View in: PubMed
    63. Loebe M, Bruckner B, Reardon MJ, van Doorn E, Estep J, Gregoric I, Masud F, Cohn W, Motomura T, Torre-Amione G, Frazier OH. Initial clinical experience of total cardiac replacement with dual HeartMate-II axial flow pumps for severe biventricular heart failure. Methodist Debakey Cardiovasc J. 2011 Jan-Mar; 7(1):40-4. PMID: 21490553.
      View in: PubMed
    64. Cohn WE, Winkler JA, Tuzun E, Hjelle A, Bassett K, Ahmad A, Frazier OH. Contrast pericardiography facilitates intrapericardial navigation under fluoroscopy. Ann Thorac Surg. 2010 Nov; 90(5):1537-40. PMID: 20971258.
      View in: PubMed
    65. Cohn WE, Demirozu ZT, Frazier OH. Surgical closure of left ventricular outflow tract after left ventricular assist device implantation in patients with aortic valve pathology. J Heart Lung Transplant. 2011 Jan; 30(1):59-63. PMID: 20884246.
      View in: PubMed
    66. Cohn WE. A transthoracic, left ventricular vent facilitates challenging sternal reentry. Ann Thorac Surg. 2010 Aug; 90(2):679-80. PMID: 20667388.
      View in: PubMed
    67. Sellke FW, Chu LM, Cohn WE. Current state of surgical myocardial revascularization. Circ J. 2010 Jun; 74(6):1031-7. PMID: 20467145.
      View in: PubMed
    68. Tuzun E, Narin C, Gregoric ID, Cohn WE, Frazier OH. Ventricular assist device outflow-graft site: effect on myocardial blood flow. J Surg Res. 2011 Nov; 171(1):71-5. PMID: 20605602.
      View in: PubMed
    69. Khalil HA, Kerr DT, Schusterman MA, Cohn WE, Frazier OH, Radovancevic B. Induced pulsation of a continuous-flow total artificial heart in a mock circulatory system. J Heart Lung Transplant. 2010 May; 29(5):568-73. PMID: 20153967.
      View in: PubMed
    70. Frazier OH, Khalil HA, Benkowski RJ, Cohn WE. Optimization of axial-pump pressure sensitivity for a continuous-flow total artificial heart. J Heart Lung Transplant. 2010 Jun; 29(6):687-91. PMID: 20133164.
      View in: PubMed
    71. Cohn WE. Advances in surgical treatment of acute and chronic coronary artery disease. Tex Heart Inst J. 2010; 37(3):328-30. PMID: 20548814.
      View in: PubMed
    72. Shalli S, Boyle EM, Saeed D, Fukamachi K, Cohn WE, Gillinov AM. The active tube clearance system: a novel bedside chest-tube clearance device. Innovations (Phila). 2010 Jan; 5(1):42-7. PMID: 22437275.
      View in: PubMed
    73. Frazier OH, Tuzun E, Narin C, Cohn WE. Right ventricle-sparing left ventricular resection and replacement with a continuous-flow rotary blood pump: an in vivo experiment. Tex Heart Inst J. 2010; 37(3):276-9. PMID: 20548801.
      View in: PubMed
    74. Cohn WE. New tools and techniques to facilitate off-pump left ventricular assist device implantation. Tex Heart Inst J. 2010; 37(5):559-61. PMID: 20978568.
      View in: PubMed
    75. Tuzun E, Cohn WE, Gilbert N, Winkler JA, Costas G, Conger JL, Frazier OH. Elective tracheotomy facilitates total artificial heart implantation in calves. ASAIO J. 2009 Sep-Oct; 55(5):456-8. PMID: 19672192.
      View in: PubMed
    76. Jafar M, Gregoric ID, Radovancevic R, Cohn WE, McGuire N, Frazier OH. Urgent exchange of a HeartMate II left ventricular assist device after percutaneous lead fracture. ASAIO J. 2009 Sep-Oct; 55(5):523-4. PMID: 19730010.
      View in: PubMed
    77. Shalli S, Saeed D, Fukamachi K, Gillinov AM, Cohn WE, Perrault LP, Boyle EM. Chest tube selection in cardiac and thoracic surgery: a survey of chest tube-related complications and their management. J Card Surg. 2009 Sep-Oct; 24(5):503-9. PMID: 19740284.
      View in: PubMed
    78. Khalil HA, Metcalfe RW, Kleis SJ, Lee EL, Gilbert NL, Kerr DT, Frazier OH, Cohn WE. Flow visualization techniques in a mock ventricle supported by a nonpulsatile left ventricular assist device. ASAIO J. 2009 Jul-Aug; 55(4):323-7. PMID: 19512887.
      View in: PubMed
    79. Frazier OH, Cohn WE, Tuzun E, Winkler JA, Gregoric ID. Continuous-flow total artificial heart supports long-term survival of a calf. Tex Heart Inst J. 2009; 36(6):568-74. PMID: 20069083.
      View in: PubMed
    80. Akay MH, Danch MA, Cohn WE, Frazier OH. Reconstruction of the fibrous trigone. Tex Heart Inst J. 2009; 36(5):475-6. PMID: 19876433.
      View in: PubMed
    81. de la Cruz KI, Tsai PI, Cohn WE, Cooley DA. Revascularization treatment recommendations based on atherosclerotic disease distribution: coronary artery bypass grafting versus stenting. Curr Atheroscler Rep. 2008 Oct; 10(5):434-7. PMID: 18706285.
      View in: PubMed
    82. Cohn WE, Fikfak V, Gregoric ID, Frazier OH. Retention of left ventricular assist device outflow grafts after transplantation. J Heart Lung Transplant. 2008 Aug; 27(8):865-8. PMID: 18656799.
      View in: PubMed
    83. Khalil HA, Cohn WE, Metcalfe RW, Frazier OH. Preload sensitivity of the Jarvik 2000 and HeartMate II left ventricular assist devices. ASAIO J. 2008 May-Jun; 54(3):245-8. PMID: 18496273.
      View in: PubMed
    84. Fukuda S, Gillinov AM, Liddicoat JR, Saracino G, Hayase M, Cohn WE, Schneider CW, Shiota T. Maintenance of geometric alterations associated with percutaneous mitral valve repair: real-time three-dimensional echocardiographic assessment in an ovine model. J Heart Valve Dis. 2008 May; 17(3):276-82. PMID: 18592924.
      View in: PubMed
    85. Gregoric ID, Bruckner BA, Jacob L, Kar B, Cohn WE, La Francesca S, Frazier OH. Clinical experience with sternotomy versus subcostal approach for exchange of the HeartMate XVE to the HeartMate II ventricular assist device. Ann Thorac Surg. 2008 May; 85(5):1646-9. PMID: 18442556.
      View in: PubMed
    86. Khalil HA, Kerr DT, Franchek MA, Metcalfe RW, Benkowski RJ, Cohn WE, Tuzun E, Radovancevic B, Frazier OH, Kadipasaoglu KA. Continuous flow total artificial heart: modeling and feedback control in a mock circulatory system. ASAIO J. 2008 May-Jun; 54(3):249-55. PMID: 18496274.
      View in: PubMed
    87. Gregoric ID, La Francesca S, Myers T, Cohn W, Loyalka P, Kar B, Gemmato C, Frazier OH. A less invasive approach to axial flow pump insertion. J Heart Lung Transplant. 2008 Apr; 27(4):423-6. PMID: 18374879.
      View in: PubMed
    88. Bruckner BA, Jacob LP, Gregoric ID, Loyalka P, Kar B, Cohn WE, La Francesca S, Radovancevic B, Frazier OH. Clinical experience with the TandemHeart percutaneous ventricular assist device as a bridge to cardiac transplantation. Tex Heart Inst J. 2008; 35(4):447-50. PMID: 19156239.
      View in: PubMed
    89. Morris CD, Gregoric ID, Cooley DA, Cohn WE, Loyalka P, Frazier OH. Placement of a continuous-flow ventricular assist device in the failing ventricle of an adult patient with complex cyanotic congenital heart disease. Heart Surg Forum. 2008; 11(3):E143-4. PMID: 18583283.
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    90. Gregoric ID, Jacob LP, La Francesca S, Bruckner BA, Cohn WE, Loyalka P, Kar B, Frazier OH. The TandemHeart as a bridge to a long-term axial-flow left ventricular assist device (bridge to bridge). Tex Heart Inst J. 2008; 35(2):125-9. PMID: 18612448.
      View in: PubMed
    91. Cohn WE, Gregoric ID, Radovancevic B, Wolf RK, Frazier OH. Atrial fibrillation after cardiac transplantation: experience in 498 consecutive cases. Ann Thorac Surg. 2008 Jan; 85(1):56-8. PMID: 18154778.
      View in: PubMed
    92. Gregoric ID, Cohn WE, Akay MH, La Francesca S, Myers T, Frazier OH. CentriMag left ventricular assist system: cannulation through a right minithoracotomy. Tex Heart Inst J. 2008; 35(2):184-5. PMID: 18612493.
      View in: PubMed
    93. Cohn WE, Gregoric ID, Radovancevic B, Frazier OH. A felt plug simplifies left ventricular assist device removal after successful bridge to recovery. J Heart Lung Transplant. 2007 Nov; 26(11):1209-11. PMID: 18022090.
      View in: PubMed
    94. Palanichamy N, Letsou GV, Cohn W, La Francesca S, Kar B, Gregoric ID. High cardiac output due to fistula after cardiac transplantation. Congest Heart Fail. 2007 Jul-Aug; 13(4):237-9. PMID: 17673877.
      View in: PubMed
    95. Mommerot A, Aubin MC, Carrier M, Cohn WE, Perrault LP. Use of the Purified Poloxamer 407 for Temporary Coronary Occlusion in Off-Pump CABG Does Not Cause Myocardial Injury. Innovations (Phila). 2007 Jul; 2(4):201-4. PMID: 22437061.
      View in: PubMed
    96. Cohn WE, Gregoric ID, Frazier OH. Reinforcement of left ventricular assist device outflow grafts to prevent kinking. Ann Thorac Surg. 2007 Jul; 84(1):301-2. PMID: 17588447.
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    97. La Francesca S, Gregoric ID, Cohn WE, Frazier OH. Successful resection of a primary left ventricular schwannoma. Ann Thorac Surg. 2007 May; 83(5):1881-2. PMID: 17462424.
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    98. Daimon M, Gillinov AM, Liddicoat JR, Saracino G, Fukuda S, Koyama Y, Hayase M, Cohn WE, Ellis SG, Thomas JD, Shiota T. Dynamic change in mitral annular area and motion during percutaneous mitral annuloplasty for ischemic mitral regurgitation: preliminary animal study with real-time 3-dimensional echocardiography. J Am Soc Echocardiogr. 2007 Apr; 20(4):381-8. PMID: 17400117.
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    99. Cohn WE, Gregoric ID, La Francesca S, Frazier OH. Bedside right ventricular assist device removal in the conscious patient. Ann Thorac Surg. 2007 Apr; 83(4):1556-7. PMID: 17383390.
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    100. Cohn W, Gregoric ID, Frazier OH. Staged reoperation: a novel strategy for high-risk patients. Ann Thorac Surg. 2007 Apr; 83(4):1558-9. PMID: 17383391.
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    101. Tuzun E, Roberts K, Cohn WE, Sargin M, Gemmato CJ, Radovancevic B, Frazier OH. In vivo evaluation of the HeartWare centrifugal ventricular assist device. Tex Heart Inst J. 2007; 34(4):406-11. PMID: 18172519.
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    102. Cohn WE, Morris CD, Reverdin S, Frazier OH, Gregoric ID. Intraoperative TandemHeart implantation as an adjunct to high-risk valve surgery. Tex Heart Inst J. 2007; 34(4):457-8. PMID: 18172530.
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    103. Cohn WE, Tuzun E, Simonak R, Baimbridge F. Hemostatic control of coronary arteries with poloxamer 407 reverse-thermal polymer during off-pump coronary artery bypass surgery in a pig model. Innovations (Phila). 2007 Jan; 2(1):36-9. PMID: 22436876.
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    104. Schalch W, Cohn W, Barker FM, Köpcke W, Mellerio J, Bird AC, Robson AG, Fitzke FF, van Kuijk FJ. Xanthophyll accumulation in the human retina during supplementation with lutein or zeaxanthin - the LUXEA (LUtein Xanthophyll Eye Accumulation) study. Arch Biochem Biophys. 2007 Feb 15; 458(2):128-35. PMID: 17084803.
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    105. Bouchot O, Aubin MC, Carrier M, Cohn WE, Perrault LP. Temporary coronary artery occlusion during off-pump coronary artery bypass grafting with the new poloxamer P407 does not cause endothelial dysfunction in epicardial coronary arteries. J Thorac Cardiovasc Surg. 2006 Nov; 132(5):1144-9. PMID: 17059936.
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    106. Aubin MC, Bouchot O, Carrier M, Cohn WE, Perrault LP. Temporary internal thoracic artery occlusion during off-pump coronary artery bypass grafting with the new poloxamer P407 does not cause endothelial dysfunction. J Thorac Cardiovasc Surg. 2006 Sep; 132(3):685-6. PMID: 16935129.
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    107. Bourque K, Dague C, Farrar D, Harms K, Tamez D, Cohn W, Tuzun E, Poirier V, Frazier OH. In vivo assessment of a rotary left ventricular assist device-induced artificial pulse in the proximal and distal aorta. Artif Organs. 2006 Aug; 30(8):638-42. PMID: 16911321.
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    108. Frazier OH, Gregoric ID, Cohn WE. Initial experience with non-thoracic, extraperitoneal, off-pump insertion of the Jarvik 2000 Heart in patients with previous median sternotomy. J Heart Lung Transplant. 2006 May; 25(5):499-503. PMID: 16678026.
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    109. Frazier OH, Tuzun E, Cohn WE, Conger JL, Kadipasaoglu KA. Total heart replacement using dual intracorporeal continuous-flow pumps in a chronic bovine model: a feasibility study. ASAIO J. 2006 Mar-Apr; 52(2):145-9. PMID: 16557099.
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    110. Amir O, Radovancevic B, Delgado RM, Kar B, Radovancevic R, Henderson M, Cohn WE, Smart FW. Peripheral vascular reactivity in patients with pulsatile vs axial flow left ventricular assist device support. J Heart Lung Transplant. 2006 Apr; 25(4):391-4. PMID: 16563966.
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    111. Cohn WE. Percutaneous valve interventions: where we are and where we are headed. Am Heart Hosp J. 2006; 4(3):186-91. PMID: 16894254.
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    112. Cohn WE, Frazier OH. Off-pump insertion of an extracorporeal LVAD through a left upper-quadrant incision. Tex Heart Inst J. 2006; 33(1):48-50. PMID: 16572869.
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    113. Amir O, Delgado RM, Kar B, Gregoric ID, Radovancevic B, Smart F, Cohn W. Recovery from multi-organ failure in a patient with a continuous-flow left ventricular assist device. J Heart Lung Transplant. 2006 Jan; 25(1):148. PMID: 16399549.
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    114. Smith RD, Radovancevic B, Gregoric ID, Cohn WE, Frazier OH. Orthotopic retransplantation in heterotopic transplant recipients: 3 case reports. J Heart Lung Transplant. 2006 Feb; 25(2):245-7. PMID: 16446229.
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    115. Boodhwani M, Cohn WE, Feng J, Ramlawi B, Mieno S, Schwarz A, Sellke FW. Safety and efficacy of a novel gel for vascular occlusion in off-pump surgery. Ann Thorac Surg. 2005 Dec; 80(6):2333-7. PMID: 16305901.
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    116. Cohn W, Radovancevic B, Amir O, Smith R, Smart F, Frazier OH. Aorta-to-left-atrial shunting through a previously performed heterotopic heart transplant: an unusual complication of orthotopic re-transplantation. J Heart Lung Transplant. 2005 Dec; 24(12):2290-2. PMID: 16364884.
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    117. Amir O, Delgado RM, Kar B, Gregoric ID, Radovancevic B, Smart F, Cohn W. Recovery from multi-organ failure in a patient with a continuous-flow left ventricular assist device. J Heart Lung Transplant. 2005 Aug; 24(8):1128-9. PMID: 16102456.
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    118. Frazier OH, Tuzun E, Cohn W, Tamez D, Kadipasaoglu KA. Total heart replacement with dual centrifugal ventricular assist devices. ASAIO J. 2005 May-Jun; 51(3):224-9. PMID: 15968951.
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    119. Daimon M, Shiota T, Gillinov AM, Hayase M, Ruel M, Cohn WE, Blacker SJ, Liddicoat JR. Percutaneous mitral valve repair for chronic ischemic mitral regurgitation: a real-time three-dimensional echocardiographic study in an ovine model. Circulation. 2005 May 03; 111(17):2183-9. PMID: 15851597.
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    120. Ullmann U, Metzner J, Frank T, Cohn W, Riegger C. Safety, tolerability, and pharmacokinetics of single ascending doses of synthetic genistein (Bonistein) in healthy volunteers. Adv Ther. 2005 Jan-Feb; 22(1):65-78. PMID: 15943224.
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    121. Cohn WE. New surgical approaches for coronary disease: what's coming? Tex Heart Inst J. 2005; 32(3):354-7. PMID: 16392217.
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    122. Cheng D, Allen K, Cohn W, Connolly M, Edgerton J, Falk V, Martin J, Ohtsuka T, Vitali R. Endoscopic vascular harvest in coronary artery bypass grafting surgery: a meta-analysis of randomized trials and controlled trials. Innovations (Phila). 2005; 1(2):61-74. PMID: 22436546.
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    123. Allen K, Cheng D, Cohn W, Connolly M, Edgerton J, Falk V, Martin J, Ohtsuka T, Vitali R. Endoscopic Vascular Harvest in Coronary Artery Bypass Grafting Surgery: A Consensus Statement of the International Society of Minimally Invasive Cardiothoracic Surgery (ISMICS) 2005. Innovations (Phila). 2005; 1(2):51-60. PMID: 22436545.
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    124. Cohn WE. Surgical coronary revascularization remains relevant in the era of stents. Curr Opin Cardiol. 2004 Nov; 19(6):589-92. PMID: 15502503.
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    125. Liddicoat JR, Mac Neill BD, Gillinov AM, Cohn WE, Chin CH, Prado AD, Pandian NG, Oesterle SN. Percutaneous mitral valve repair: a feasibility study in an ovine model of acute ischemic mitral regurgitation. Catheter Cardiovasc Interv. 2003 Nov; 60(3):410-6. PMID: 14571496.
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    126. Ruel MA, Sellke FW, Bianchi C, Khan TA, Faro R, Zhang JP, Cohn WE. Endogenous myocardial angiogenesis and revascularization using a gastric submucosal patch. Ann Thorac Surg. 2003 May; 75(5):1443-9. PMID: 12735560.
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    127. Cohn WE, Ruel M, Zhang JP, Sellke FW, Johnson RG. Internal thoracic artery flow competition: studies in a canine H-graft model. Eur J Cardiothorac Surg. 2003 Jan; 23(1):56-9. PMID: 12493505.
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    128. Ruel M, Streeter RB, de la Torre R, Liddicoat JR, Cohn WE. Intracardiac ultrasonic suture welding for knotless mitral valve replacement. Eur J Cardiothorac Surg. 2002 Feb; 21(2):245-8. PMID: 11825730.
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    129. Hernandez F, Cohn WE, Baribeau YR, Tryzelaar JF, Charlesworth DC, Clough RA, Klemperer JD, Morton JR, Westbrook BM, Olmstead EM, O'Connor GT. In-hospital outcomes of off-pump versus on-pump coronary artery bypass procedures: a multicenter experience. Ann Thorac Surg. 2001 Nov; 72(5):1528-33; discussion 1533-4. PMID: 11722038.
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    130. Ross MJ, Sakoulas G, Manning WJ, Cohn WE, Lisbon A. Corynebacterium jeikeium native valve endocarditis following femoral access for coronary angiography. Clin Infect Dis. 2001 Apr 01; 32(7):E120-1. PMID: 11264050.
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    131. Cohn WE, de La Torre R, Liddicoat JR. Is the future of cardiac surgery in the hands of the interventional cardiologist? Heart Surg Forum. 2001; 4(4):297-300. PMID: 11827854.
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    132. Maslow AD, Regan MM, Heindle S, Panzica P, Cohn WE, Johnson RG. Postoperative atrial tachyarrhythmias in patients undergoing coronary artery bypass graft surgery without cardiopulmonary bypass: a role for intraoperative magnesium supplementation. J Cardiothorac Vasc Anesth. 2000 Oct; 14(5):524-30. PMID: 11052432.
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    133. Cohn WE, Weintraub RM, Sellke FW. Innovative minimally invasive surgical approaches to coronary revascularization in the high risk patient. Heart Surg Forum. 2000; 3(3):185-8. PMID: 11074970.
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    134. Miesfeldt S, Jones SM, Cohn W, Lippert M, Haden K, Turner BL, Martin-Fries T, Clark SM. Men's attitudes regarding genetic testing for hereditary prostate cancer risk. Urology. 2000 Jan; 55(1):46-50. PMID: 10654893.
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    135. Maslow A, Aronson S, Jacobsohn E, Cohn WE, Johnson RG. Case 6--1999. Off-pump coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth. 1999 Dec; 13(6):764-81. PMID: 10622664.
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    136. Cohn WE, Sellke FW, Sirois C, Lisbon A, Johnson RG. Surgical ICU recidivism after cardiac operations. Chest. 1999 Sep; 116(3):688-92. PMID: 10492272.
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    137. Maslow AD, Park KW, Pawlowski J, Haering JM, Cohn WE. Minimally invasive direct coronary artery bypass grafting: changes in anesthetic management and surgical procedure. J Cardiothorac Vasc Anesth. 1999 Aug; 13(4):417-23. PMID: 10468254.
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    138. Cohn WE, Sirois CA, Johnson RG. Atrial fibrillation after minimally invasive coronary artery bypass grafting: A retrospective, matched study. J Thorac Cardiovasc Surg. 1999 Feb; 117(2):298-301. PMID: 9918971.
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    139. Hoenig SJ, Hodin RA, Novak G, Cohn WE. Videoscopic harvest of the inferior epigastric artery. Ann Thorac Surg. 1999 Feb; 67(2):565-6. PMID: 10197701.
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    140. Maslow A, Lowenstein E, Steriti J, Leckie R, Cohn W, Haering M. Left ventricular thrombi: intraoperative detection by transesophageal echocardiography and recognition of a source of post CABG embolic stroke: a case series. Anesthesiology. 1998 Nov; 89(5):1257-62. PMID: 9822018.
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    141. Cohn WE, Suen HC, Weintraub RM, Johnson RG. The "H" graft: an alternative approach for performing minimally invasive direct coronary artery bypass. J Thorac Cardiovasc Surg. 1998 Jan; 115(1):148-51. PMID: 9451058.
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    142. Suen HC, Johnson RG, Weintraub RM, Maslow A, Comunale ME, Cohn WE. Minimally invasive direct coronary artery bypass: our experience with 32 patients. Int J Cardiol. 1997 Dec 01; 62 Suppl 1:S95-100. PMID: 9464591.
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    143. Johnson RG, Cohn WE, Thurer RL, McCarthy JR, Sirois CA, Weintraub RM. Cutaneous closure after cardiac operations: a controlled, randomized, prospective comparison of intradermal versus staple closures. Ann Surg. 1997 Nov; 226(5):606-12. PMID: 9389394.
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    144. Johnson RG, Sirois C, Thurer RL, Sellke FW, Cohn WE, Kuntz RE, Weintraub RM. Predictors of CABG within one year of successful PTCA: a retrospective, case-control study. Ann Thorac Surg. 1997 Jul; 64(1):3-7; discussion 7-8. PMID: 9236327.
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    145. Pawlowski J, Haering JM, Comunale ME, Mashikian J, Reynolds D, Johnson R, Cohn W. Minimally invasive anesthesia should accompany minimally invasive surgery. J Cardiothorac Vasc Anesth. 1997 Jun; 11(4):536-7. PMID: 9188010.
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    146. Hariawala MD, Cohn WE, Tofukuji M, Allman GW, Suen HC, Johnson RG. Re: The latissimus dorsi perforator-based fasciocutaneous flap. Ann Plast Surg. 1997 May; 38(5):550. PMID: 9160145.
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    147. Sellke FW, Wang SY, Stamler A, Johnson RG, Cohn WE, Weintraub RM. Changes in autonomic response of the cerebral circulation after normothermic extracorporeal circulation. J Thorac Cardiovasc Surg. 1996 Aug; 112(2):450-61. PMID: 8751514.
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    148. Friedman M, Wang SY, Sellke FW, Cohn WE, Weintraub RM, Johnson RG. Neutrophil adhesion blockade with NPC 15669 decreases pulmonary injury after total cardiopulmonary bypass. J Thorac Cardiovasc Surg. 1996 Feb; 111(2):460-8. PMID: 8583821.
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    149. Johnson RG, Sirois C, Watkins JF, Thurer RL, Sellke FW, Cohn WE, Kuntz RE, Weintraub RM. CABG after successful PTCA: a case-control study. Ann Thorac Surg. 1995 Jun; 59(6):1391-6. PMID: 7771816.
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