Loading...
Header Logo
Keywords
Last Name
Institution

VIJAY K. YECHOOR

TitleAdjunct Associate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
DivisionMedicine-Endocrinology
vCardDownload vCard
    Other Positions
    TitleAdjunct Associate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology


    Collapse ORNG Applications 
    Collapse Verify Publications

    Collapse Research 
    Collapse research activities and funding
    K08DK068391     (YECHOOR, VIJAY K)Jul 1, 2004 - Jun 30, 2009
    NIH/NIDDK
    Islet Neogenesis with Ngn3 Therapy Reverses Diabetes
    Role: Principal Investigator

    R03DK078716     (YECHOOR, VIJAY K)Jan 1, 2009 - Dec 31, 2010
    NIH/NIDDK
    Reversing Autoimmune Diabetes with Gene Therapy Induced Islet Neogenesis
    Role: Principal Investigator

    R56DK089061     (YECHOOR, VIJAY K)Jul 1, 2010 - Jun 30, 2012
    NIH/NIDDK
    Circadian Control of Islet Function
    Role: Principal Investigator

    R01DK097160     (YECHOOR, VIJAY K)Feb 1, 2014 - May 31, 2019
    NIH/NIDDK
    Circadian Clock and Beta Cell Stress Adaptation
    Role: Principal Investigator

    I01BX002678     (YECHOOR, VIJAY K)Jan 1, 2016 - Dec 31, 2019
    VA
    Tead1 - A Regulator of Quiescence and Proliferation in Pancreatic Beta Cells
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Liu R, Xiong X, Nam D, Yechoor V, Ma K. SRF-MRTF signaling suppresses brown adipocyte development by modulating TGF-ß/BMP pathway. Mol Cell Endocrinol. 2020 Jun 27; 110920. PMID: 32603734.
      View in: PubMed
    2. Liu R, Jagannathan R, Sun L, Li F, Yang P, Lee J, Negi V, Perez-Garcia EM, Shiva S, Yechoor VK, Moulik M. Tead1 is essential for mitochondrial function in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2020 Jul 01; 319(1):H89-H99. PMID: 32502376.
      View in: PubMed
    3. Yin H, Li W, Chatterjee S, Xiong X, Saha P, Yechoor V, Ma K. Metabolic-sensing of the skeletal muscle clock coordinates fuel oxidation. FASEB J. 2020 May; 34(5):6613-6627. PMID: 32212194.
      View in: PubMed
    4. Liu H, Zhang CH, Ammanamanchi N, Suresh S, Lewarchik C, Rao K, Uys GM, Han L, Abrial M, Yimlamai D, Ganapathy B, Guillermier C, Chen N, Khaladkar M, Spaethling J, Eberwine JH, Kim J, Walsh S, Choudhury S, Little K, Francis K, Sharma M, Viegas M, Bais A, Kostka D, Ding J, Bar-Joseph Z, Wu Y, Yechoor V, Moulik M, Johnson J, Weinberg J, Reyes-Múgica M, Steinhauser ML, Kühn B. Control of cytokinesis by ß-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment. Sci Transl Med. 2019 10 09; 11(513). PMID: 31597755.
      View in: PubMed
    5. Chatterjee S, Yin H, Li W, Lee J, Yechoor VK, Ma K. The Nuclear Receptor and Clock Repressor Rev-erba Suppresses Myogenesis. Sci Rep. 2019 03 14; 9(1):4585. PMID: 30872796.
      View in: PubMed
    6. Liu R, Jagannathan R, Li F, Lee J, Balasubramanyam N, Kim BS, Yang P, Yechoor VK, Moulik M. Tead1 is required for perinatal cardiomyocyte proliferation. PLoS One. 2019; 14(2):e0212017. PMID: 30811446.
      View in: PubMed
    7. Xie A, Li R, Jiang T, Yan H, Zhang H, Yang Y, Yang L, Yechoor V, Chan L, Chen W. Anti-TCRß mAb in Combination With Neurogenin3 Gene Therapy Reverses Established Overt Type 1 Diabetes in Female NOD Mice. Endocrinology. 2017 10 01; 158(10):3140-3151. PMID: 28977608.
      View in: PubMed
    8. Gao H, Ho E, Balakrishnan M, Yechoor V, Yallampalli C. Decreased insulin secretion in pregnant rats fed a low protein diet. Biol Reprod. 2017 Oct 01; 97(4):627-635. PMID: 29025046.
      View in: PubMed
    9. Liu R, Lee J, Kim BS, Wang Q, Buxton SK, Balasubramanyam N, Kim JJ, Dong J, Zhang A, Li S, Gupte AA, Hamilton DJ, Martin JF, Rodney GG, Coarfa C, Wehrens XH, Yechoor VK, Moulik M. Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy. JCI Insight. 2017 09 07; 2(17). PMID: 28878117.
      View in: PubMed
    10. Pradhan G, Wu CS, Han Lee J, Kanikarla P, Guo S, Yechoor VK, Samson SL, Sun Y. Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R. Sci Rep. 2017 04 20; 7(1):979. PMID: 28428639.
      View in: PubMed
    11. Goo YH, Yechoor VK, Paul A. Transcriptional profiling of foam cells in response to hypercholesterolemia. Genom Data. 2016 Sep; 9:37-9. PMID: 27408807.
      View in: PubMed
    12. Goo YH, Son SH, Yechoor VK, Paul A. Transcriptional Profiling of Foam Cells Reveals Induction of Guanylate-Binding Proteins Following Western Diet Acceleration of Atherosclerosis in the Absence of Global Changes in Inflammation. J Am Heart Assoc. 2016 Apr 18; 5(4):e002663. PMID: 27091181.
      View in: PubMed
    13. Nam D, Yechoor VK, Ma K. Molecular clock integration of brown adipose tissue formation and function. Adipocyte. 2016 Apr-Jun; 5(2):243-50. PMID: 27385482.
      View in: PubMed
    14. Li R, Lee J, Kim MS, Liu V, Moulik M, Li H, Yi Q, Xie A, Chen W, Yang L, Li Y, Tsai TH, Oka K, Chan L, Yechoor V. Erratum. PD-L1-Driven Tolerance Protects Neurogenin3-Induced Islet Neogenesis to Reverse Established Type 1 Diabetes in NOD Mice. Diabetes 2015;64:529-540. Diabetes. 2015 Jul; 64(7):2685. PMID: 26106199.
      View in: PubMed
    15. Nam D, Chatterjee S, Yin H, Liu R, Lee J, Yechoor VK, Ma K. Novel Function of Rev-erba in Promoting Brown Adipogenesis. Sci Rep. 2015 Jun 10; 5:11239. PMID: 26058812.
      View in: PubMed
    16. Nam D, Guo B, Chatterjee S, Chen MH, Nelson D, Yechoor VK, Ma K. The adipocyte clock controls brown adipogenesis through the TGF-ß and BMP signaling pathways. J Cell Sci. 2015 May 01; 128(9):1835-47. PMID: 25749863.
      View in: PubMed
    17. Li R, Lee J, Kim MS, Liu V, Moulik M, Li H, Yi Q, Xie A, Chen W, Yang L, Li Y, Tsai TH, Oka K, Chan L, Yechoor V. PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice. Diabetes. 2015 Feb; 64(2):529-40. PMID: 25332429.
      View in: PubMed
    18. Lee J, Moulik M, Fang Z, Saha P, Zou F, Xu Y, Nelson DL, Ma K, Moore DD, Yechoor VK. Bmal1 and ß-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced ß-cell failure in mice. Mol Cell Biol. 2013 Jun; 33(11):2327-38. PMID: 23547261.
      View in: PubMed
    19. Chatterjee S, Nam D, Guo B, Kim JM, Winnier GE, Lee J, Berdeaux R, Yechoor VK, Ma K. Brain and muscle Arnt-like 1 is a key regulator of myogenesis. J Cell Sci. 2013 May 15; 126(Pt 10):2213-24. PMID: 23525013.
      View in: PubMed
    20. Dixit SS, Wang T, Manzano EJ, Yoo S, Lee J, Chiang DY, Ryan N, Respress JL, Yechoor VK, Wehrens XH. Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance. PLoS One. 2013; 8(3):e58655. PMID: 23516528.
      View in: PubMed
    21. Li R, Oka K, Yechoor V. Neo-islet formation in liver of diabetic mice by helper-dependent adenoviral vector-mediated gene transfer. J Vis Exp. 2012 Oct 10; (68). PMID: 23093064.
      View in: PubMed
    22. Guo B, Chatterjee S, Li L, Kim JM, Lee J, Yechoor VK, Minze LJ, Hsueh W, Ma K. The clock gene, brain and muscle Arnt-like 1, regulates adipogenesis via Wnt signaling pathway. FASEB J. 2012 Aug; 26(8):3453-63. PMID: 22611086.
      View in: PubMed
    23. Chen W, Chang B, Saha P, Hartig SM, Li L, Reddy VT, Yang Y, Yechoor V, Mancini MA, Chan L. Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation. Mol Cell Biol. 2012 Mar; 32(6):1099-111. PMID: 22269949.
      View in: PubMed
    24. Lee J, Kim MS, Li R, Liu VY, Fu L, Moore DD, Ma K, Yechoor VK. Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in ß-cells. Islets. 2011 Nov-Dec; 3(6):381-8. PMID: 22045262.
      View in: PubMed
    25. Park YJ, Kim SC, Kim J, Anakk S, Lee JM, Tseng HT, Yechoor V, Park J, Choi JS, Jang HC, Lee KU, Novak CM, Moore DD, Lee YK. Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner. J Lipid Res. 2011 Dec; 52(12):2234-44. PMID: 21949050.
      View in: PubMed
    26. Yechoor V, Chan L. Minireview: beta-cell replacement therapy for diabetes in the 21st century: manipulation of cell fate by directed differentiation. Mol Endocrinol. 2010 Aug; 24(8):1501-11. PMID: 20219891.
      View in: PubMed
    27. Yechoor V, Liu V, Paul A, Lee J, Buras E, Ozer K, Samson S, Chan L. Gene therapy with neurogenin 3 and betacellulin reverses major metabolic problems in insulin-deficient diabetic mice. Endocrinology. 2009 Nov; 150(11):4863-73. PMID: 19819964.
      View in: PubMed
    28. Chen W, Yechoor VK, Chang BH, Li MV, March KL, Chan L. The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation. Endocrinology. 2009 Oct; 150(10):4552-61. PMID: 19574402.
      View in: PubMed
    29. Yechoor V, Liu V, Espiritu C, Paul A, Oka K, Kojima H, Chan L. Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes. Dev Cell. 2009 Mar; 16(3):358-73. PMID: 19289082.
      View in: PubMed
    30. Samson SL, Gonzalez EV, Yechoor V, Bajaj M, Oka K, Chan L. Gene therapy for diabetes: metabolic effects of helper-dependent adenoviral exendin 4 expression in a diet-induced obesity mouse model. Mol Ther. 2008 Nov; 16(11):1805-12. PMID: 18781141.
      View in: PubMed
    31. Paul A, Chang BH, Li L, Yechoor VK, Chan L. Deficiency of adipose differentiation-related protein impairs foam cell formation and protects against atherosclerosis. Circ Res. 2008 Jun 20; 102(12):1492-501. PMID: 18483409.
      View in: PubMed
    32. Paul A, Yechoor V, Raja R, Li L, Chan L. Microarray gene profiling of laser-captured cells: a new tool to study atherosclerosis in mice. Atherosclerosis. 2008 Oct; 200(2):257-63. PMID: 18289551.
      View in: PubMed
    33. Tseng YH, Butte AJ, Kokkotou E, Yechoor VK, Taniguchi CM, Kriauciunas KM, Cypess AM, Niinobe M, Yoshikawa K, Patti ME, Kahn CR. Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin. Nat Cell Biol. 2005 Jun; 7(6):601-11. PMID: 15895078.
      View in: PubMed
    34. Niendorf ER, Parker JA, Yechoor V, Garber JR, Boiselle PM. Thymic hyperplasia in thyroid cancer patients. J Thorac Imaging. 2005 Feb; 20(1):1-4. PMID: 15729115.
      View in: PubMed
    35. Yechoor VK, Patti ME, Ueki K, Laustsen PG, Saccone R, Rauniyar R, Kahn CR. Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice. Proc Natl Acad Sci U S A. 2004 Nov 23; 101(47):16525-30. PMID: 15546994.
      View in: PubMed
    36. Paul A, Ko KW, Li L, Yechoor V, McCrory MA, Szalai AJ, Chan L. C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2004 Feb 10; 109(5):647-55. PMID: 14744975.
      View in: PubMed
    37. Castro-Chavez F, Yechoor VK, Saha PK, Martinez-Botas J, Wooten EC, Sharma S, O'Connell P, Taegtmeyer H, Chan L. Coordinated upregulation of oxidative pathways and downregulation of lipid biosynthesis underlie obesity resistance in perilipin knockout mice: a microarray gene expression profile. Diabetes. 2003 Nov; 52(11):2666-74. PMID: 14578284.
      View in: PubMed
    38. Yechoor VK, Patti ME, Saccone R, Kahn CR. Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10587-92. PMID: 12149437.
      View in: PubMed
    YECHOOR's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description