STEVEN LUDTKE

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Biochemistry & Molecular Biology
AddressOne Baylor Plaza
Houston, TX 77030
vCardDownload vCard

    Collapse ORNG Applications 
    Collapse Verify Publications

    Collapse Biography 
    Collapse awards and honors
    2008Burton Medal, Microcsopy Society of America

    Collapse Research 
    Collapse research activities and funding
    F32AR008474     (LUDTKE, STEVEN J)Jan 1, 1999
    NIH/NIAMS
    STRUCTURAL STUDIES OF RYANODINE RECEPTOR ISOFORMS
    Role: Principal Investigator

    R01GM080139     (LUDTKE, STEVEN J)Jun 1, 2006 - Nov 30, 2011
    NIH/NIGMS
    SUPPORT AND DEVELOPMENT OF EMAN FOR ELECTRON MICROSCOPY IMAGE PROCESSING
    Role: Principal Investigator

    R21GM100229     (BAKER, MATTHEW LOWELL)Sep 10, 2013 - Aug 31, 2015
    NIH/NIGMS
    Atomic Resolution Cryo-EM using Model-Based Constraints
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Terwilliger TC, Ludtke SJ, Read RJ, Adams PD, Afonine PV. Improvement of cryo-EM maps by density modification. Nat Methods. 2020 Sep; 17(9):923-927. PMID: 32807957.
      Citations: 5     Fields:    
    2. Yu X, Yi P, Hamilton RA, Shen H, Chen M, Foulds CE, Mancini MA, Ludtke SJ, Wang Z, O'Malley BW. Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes. Mol Cell. 2020 09 03; 79(5):812-823.e4. PMID: 32668201.
      Citations:    Fields:    Translation:HumansCells
    3. Li S, Su Z, Lehmann J, Stamatopoulou V, Giarimoglou N, Henderson FE, Fan L, Pintilie GD, Zhang K, Chen M, Ludtke SJ, Wang YX, Stathopoulos C, Chiu W, Zhang J. Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions. Nat Struct Mol Biol. 2019 12; 26(12):1094-1105. PMID: 31740854.
      Citations: 7     Fields:    Translation:Cells
    4. Chen M, Bell JM, Shi X, Sun SY, Wang Z, Ludtke SJ. A complete data processing workflow for cryo-ET and subtomogram averaging. Nat Methods. 2019 11; 16(11):1161-1168. PMID: 31611690.
      Citations: 1     Fields:    
    5. Levitan O, Chen M, Kuang X, Cheong KY, Jiang J, Banal M, Nambiar N, Gorbunov MY, Ludtke SJ, Falkowski PG, Dai W. Structural and functional analyses of photosystem II in the marine diatom Phaeodactylum tricornutum. Proc Natl Acad Sci U S A. 2019 08 27; 116(35):17316-17322. PMID: 31409711.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Shi X, Chen M, Yu Z, Bell JM, Wang H, Forrester I, Villarreal H, Jakana J, Du D, Luisi BF, Ludtke SJ, Wang Z. In situ structure and assembly of the multidrug efflux pump AcrAB-TolC. Nat Commun. 2019 06 14; 10(1):2635. PMID: 31201302.
      Citations: 4     Fields:    Translation:Cells
    7. Fan G, Baker MR, Wang Z, Seryshev AB, Ludtke SJ, Baker ML, Serysheva II. Cryo-EM reveals ligand induced allostery underlying InsP3R channel gating. Cell Res. 2018 12; 28(12):1158-1170. PMID: 30470765.
      Citations: 6     Fields:    Translation:AnimalsCells
    8. Bell JM, Chen M, Durmaz T, Fluty AC, Ludtke SJ. New software tools in EMAN2 inspired by EMDatabank map challenge. J Struct Biol. 2018 11; 204(2):283-290. PMID: 30189321.
      Citations: 4     Fields:    
    9. Dai W, Chen M, Myers C, Ludtke SJ, Pettitt BM, King JA, Schmid MF, Chiu W. Visualizing Individual RuBisCO and Its Assembly into Carboxysomes in Marine Cyanobacteria by Cryo-Electron Tomography. J Mol Biol. 2018 10 19; 430(21):4156-4167. PMID: 30138616.
      Citations: 6     Fields:    Translation:AnimalsCells
    10. Kim SJ, Fernandez-Martinez J, Nudelman I, Shi Y, Zhang W, Raveh B, Herricks T, Slaughter BD, Hogan JA, Upla P, Chemmama IE, Pellarin R, Echeverria I, Shivaraju M, Chaudhury AS, Wang J, Williams R, Unruh JR, Greenberg CH, Jacobs EY, Yu Z, de la Cruz MJ, Mironska R, Stokes DL, Aitchison JD, Jarrold MF, Gerton JL, Ludtke SJ, Akey CW, Chait BT, Sali A, Rout MP. Integrative structure and functional anatomy of a nuclear pore complex. Nature. 2018 03 22; 555(7697):475-482. PMID: 29539637.
      Citations: 41     Fields:    Translation:AnimalsCells
    11. Zhang K, Keane SC, Su Z, Irobalieva RN, Chen M, Van V, Sciandra CA, Marchant J, Heng X, Schmid MF, Case DA, Ludtke SJ, Summers MF, Chiu W. Structure of the 30 kDa HIV-1 RNA Dimerization Signal by a Hybrid Cryo-EM, NMR, and Molecular Dynamics Approach. Structure. 2018 03 06; 26(3):490-498.e3. PMID: 29398526.
      Citations: 8     Fields:    Translation:Cells
    12. Chen M, Dai W, Sun SY, Jonasch D, He CY, Schmid MF, Chiu W, Ludtke SJ. Convolutional neural networks for automated annotation of cellular cryo-electron tomograms. Nat Methods. 2017 Oct; 14(10):983-985. PMID: 28846087.
      Citations: 26     Fields:    Translation:Cells
    13. Yi P, Wang Z, Feng Q, Chou CK, Pintilie GD, Shen H, Foulds CE, Fan G, Serysheva I, Ludtke SJ, Schmid MF, Hung MC, Chiu W, O'Malley BW. Structural and Functional Impacts of ER Coactivator Sequential Recruitment. Mol Cell. 2017 Sep 07; 67(5):733-743.e4. PMID: 28844863.
      Citations: 15     Fields:    Translation:HumansCells
    14. Galaz-Montoya JG, Ludtke SJ. The advent of structural biology in situ by single particle cryo-electron tomography. Biophys Rep. 2017; 3(1):17-35. PMID: 28781998.
      Citations:    
    15. Cheng TC, Akey IV, Yuan S, Yu Z, Ludtke SJ, Akey CW. A Near-Atomic Structure of the Dark Apoptosome Provides Insight into Assembly and Activation. Structure. 2017 01 03; 25(1):40-52. PMID: 27916517.
      Citations: 4     Fields:    Translation:AnimalsCells
    16. Chen M, Baldwin PR, Ludtke SJ, Baker ML. De Novo modeling in cryo-EM density maps with Pathwalking. J Struct Biol. 2016 12; 196(3):289-298. PMID: 27436409.
      Citations: 15     Fields:    Translation:Cells
    17. Ludtke SJ. Single-Particle Refinement and Variability Analysis in EMAN2.1. Methods Enzymol. 2016; 579:159-89. PMID: 27572727.
      Citations: 21     Fields:    Translation:Cells
    18. Galaz-Montoya JG, Hecksel CW, Baldwin PR, Wang E, Weaver SC, Schmid MF, Ludtke SJ, Chiu W. Alignment algorithms and per-particle CTF correction for single particle cryo-electron tomography. J Struct Biol. 2016 06; 194(3):383-94. PMID: 27016284.
      Citations: 9     Fields:    Translation:Cells
    19. Bell JM, Chen M, Baldwin PR, Ludtke SJ. High resolution single particle refinement in EMAN2.1. Methods. 2016 05 01; 100:25-34. PMID: 26931650.
      Citations: 23     Fields:    
    20. Marabini R, Ludtke SJ, Murray SC, Chiu W, de la Rosa-Trevín JM, Patwardhan A, Heymann JB, Carazo JM. The Electron Microscopy eXchange (EMX) initiative. J Struct Biol. 2016 May; 194(2):156-63. PMID: 26873784.
      Citations: 4     Fields:    Translation:Humans
    21. Murray SC, Gillard BK, Ludtke SJ, Pownall HJ. Direct Measurement of the Structure of Reconstituted High-Density Lipoproteins by Cryo-EM. Biophys J. 2016 Feb 23; 110(4):810-6. PMID: 26743047.
      Citations: 4     Fields:    Translation:Cells
    22. Lawson CL, Patwardhan A, Baker ML, Hryc C, Garcia ES, Hudson BP, Lagerstedt I, Ludtke SJ, Pintilie G, Sala R, Westbrook JD, Berman HM, Kleywegt GJ, Chiu W. EMDataBank unified data resource for 3DEM. Nucleic Acids Res. 2016 Jan 04; 44(D1):D396-403. PMID: 26578576.
      Citations: 36     Fields:    
    23. Irobalieva RN, Fogg JM, Catanese DJ, Sutthibutpong T, Chen M, Barker AK, Ludtke SJ, Harris SA, Schmid MF, Chiu W, Zechiedrich L. Erratum: Structural diversity of supercoiled DNA. Nat Commun. 2015 Oct 29; 6:8851. PMID: 26511109.
      Citations: 4     Fields:    
    24. Irobalieva RN, Fogg JM, Catanese DJ, Catanese DJ, Sutthibutpong T, Chen M, Barker AK, Ludtke SJ, Harris SA, Schmid MF, Chiu W, Zechiedrich L. Structural diversity of supercoiled DNA. Nat Commun. 2015 Oct 12; 6:8440. PMID: 26455586.
      Citations: 23     Fields:    Translation:Cells
    25. Fan G, Baker ML, Wang Z, Baker MR, Sinyagovskiy PA, Chiu W, Ludtke SJ, Serysheva II. Gating machinery of InsP3R channels revealed by electron cryomicroscopy. Nature. 2015 Nov 19; 527(7578):336-41. PMID: 26458101.
      Citations: 69     Fields:    Translation:AnimalsCells
    26. Galaz-Montoya JG, Flanagan J, Schmid MF, Ludtke SJ. Single particle tomography in EMAN2. J Struct Biol. 2015 Jun; 190(3):279-90. PMID: 25956334.
      Citations: 26     Fields:    
    27. Marabini R, Carragher B, Chen S, Chen J, Cheng A, Downing KH, Frank J, Grassucci RA, Bernard Heymann J, Jiang W, Jonic S, Liao HY, Ludtke SJ, Patwari S, Piotrowski AL, Quintana A, Sorzano CO, Stahlberg H, Vargas J, Voss NR, Chiu W, Carazo JM. CTF Challenge: Result summary. J Struct Biol. 2015 Jun; 190(3):348-59. PMID: 25913484.
      Citations: 11     Fields:    
    28. Cheng A, Henderson R, Mastronarde D, Ludtke SJ, Schoenmakers RH, Short J, Marabini R, Dallakyan S, Agard D, Winn M. MRC2014: Extensions to the MRC format header for electron cryo-microscopy and tomography. J Struct Biol. 2015 Nov; 192(2):146-50. PMID: 25882513.
      Citations: 11     Fields:    
    29. Yi P, Wang Z, Feng Q, Pintilie GD, Foulds CE, Lanz RB, Ludtke SJ, Schmid MF, Chiu W, O'Malley BW. Structure of a biologically active estrogen receptor-coactivator complex on DNA. Mol Cell. 2015 Mar 19; 57(6):1047-1058. PMID: 25728767.
      Citations: 34     Fields:    Translation:HumansCells
    30. Dai W, Fu C, Khant HA, Ludtke SJ, Schmid MF, Chiu W. Zernike phase-contrast electron cryotomography applied to marine cyanobacteria infected with cyanophages. Nat Protoc. 2014 Nov; 9(11):2630-42. PMID: 25321408.
      Citations: 6     Fields:    Translation:Cells
    31. Wang Z, Hryc CF, Bammes B, Afonine PV, Jakana J, Chen DH, Liu X, Baker ML, Kao C, Ludtke SJ, Schmid MF, Adams PD, Chiu W. An atomic model of brome mosaic virus using direct electron detection and real-space optimization. Nat Commun. 2014 Sep 04; 5:4808. PMID: 25185801.
      Citations: 48     Fields:    Translation:Cells
    32. Chen Z, Fischer ER, Kouiavskaia D, Hansen BT, Ludtke SJ, Bidzhieva B, Makiya M, Agulto L, Purcell RH, Chumakov K. Cross-neutralizing human anti-poliovirus antibodies bind the recognition site for cellular receptor. Proc Natl Acad Sci U S A. 2013 Dec 10; 110(50):20242-7. PMID: 24277851.
      Citations: 17     Fields:    Translation:HumansCellsPHPublic Health
    33. Park E, Ménétret JF, Gumbart JC, Ludtke SJ, Li W, Whynot A, Rapoport TA, Akey CW. Structure of the SecY channel during initiation of protein translocation. Nature. 2014 Feb 06; 506(7486):102-6. PMID: 24153188.
      Citations: 58     Fields:    Translation:Cells
    34. Dai W, Fu C, Raytcheva D, Flanagan J, Khant HA, Liu X, Rochat RH, Haase-Pettingell C, Piret J, Ludtke SJ, Nagayama K, Schmid MF, King JA, Chiu W. Visualizing virus assembly intermediates inside marine cyanobacteria. Nature. 2013 Oct 31; 502(7473):707-10. PMID: 24107993.
      Citations: 44     Fields:    Translation:Cells
    35. Shahmoradian SH, Galaz-Montoya JG, Schmid MF, Cong Y, Ma B, Spiess C, Frydman J, Ludtke SJ, Chiu W. TRiC's tricks inhibit huntingtin aggregation. Elife. 2013 Jul 09; 2:e00710. PMID: 23853712.
      Citations: 34     Fields:    Translation:HumansCells
    36. Ludtke SJ, Serysheva II. Single-particle cryo-EM of calcium release channels: structural validation. Curr Opin Struct Biol. 2013 Oct; 23(5):755-62. PMID: 23831288.
      Citations: 8     Fields:    Translation:Cells
    37. Stoilova-McPhie S, Lynch GC, Ludtke S, Pettitt BM. Domain organization of membrane-bound factor VIII. Biopolymers. 2013 Jul; 99(7):448-59. PMID: 23616213.
      Citations: 9     Fields:    Translation:HumansCells
    38. Murray SC, Flanagan J, Popova OB, Chiu W, Ludtke SJ, Serysheva II. Validation of cryo-EM structure of IP3R1 channel. Structure. 2013 Jun 04; 21(6):900-9. PMID: 23707684.
      Citations: 24     Fields:    Translation:Cells
    39. Sergeeva OA, Chen B, Haase-Pettingell C, Ludtke SJ, Chiu W, King JA. Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers. J Biol Chem. 2013 Jun 14; 288(24):17734-44. PMID: 23612981.
      Citations: 25     Fields:    Translation:HumansCells
    40. Tolun G, Makhov AM, Ludtke SJ, Griffith JD. Details of ssDNA annealing revealed by an HSV-1 ICP8-ssDNA binary complex. Nucleic Acids Res. 2013 Jun; 41(11):5927-37. PMID: 23605044.
      Citations: 7     Fields:    Translation:Cells
    41. Zhang Q, Dai X, Cong Y, Zhang J, Chen DH, Dougherty MT, Wang J, Ludtke SJ, Schmid MF, Chiu W. Cryo-EM structure of a molluscan hemocyanin suggests its allosteric mechanism. Structure. 2013 Apr 02; 21(4):604-13. PMID: 23541894.
      Citations: 14     Fields:    Translation:AnimalsCells
    42. Rees I, Langley E, Chiu W, Ludtke SJ. EMEN2: an object oriented database and electronic lab notebook. Microsc Microanal. 2013 Feb; 19(1):1-10. PMID: 23360752.
      Citations: 7     Fields:    
    43. Patwardhan A, Carazo JM, Carragher B, Henderson R, Heymann JB, Hill E, Jensen GJ, Lagerstedt I, Lawson CL, Ludtke SJ, Mastronarde D, Moore WJ, Roseman A, Rosenthal P, Sorzano CO, Sanz-García E, Scheres SH, Subramaniam S, Westbrook J, Winn M, Swedlow JR, Kleywegt GJ. Data management challenges in three-dimensional EM. Nat Struct Mol Biol. 2012 Dec; 19(12):1203-7. PMID: 23211764.
      Citations: 24     Fields:    
    44. Ludtke SJ, Lawson CL, Kleywegt GJ, Berman H, Chiu W. The 2010 cryo-EM modeling challenge. Biopolymers. 2012 Sep; 97(9):651-4. PMID: 22696402.
      Citations: 11     Fields:    
    45. Leitner A, Joachimiak LA, Bracher A, Mönkemeyer L, Walzthoeni T, Chen B, Pechmann S, Holmes S, Cong Y, Ma B, Ludtke S, Chiu W, Hartl FU, Aebersold R, Frydman J. The molecular architecture of the eukaryotic chaperonin TRiC/CCT. Structure. 2012 May 09; 20(5):814-25. PMID: 22503819.
      Citations: 96     Fields:    Translation:AnimalsCells
    46. Baker MR, Rees I, Ludtke SJ, Chiu W, Baker ML. Constructing and validating initial Ca models from subnanometer resolution density maps with pathwalking. Structure. 2012 Mar 07; 20(3):450-63. PMID: 22405004.
      Citations: 12     Fields:    Translation:Cells
    47. Henderson R, Sali A, Baker ML, Carragher B, Devkota B, Downing KH, Egelman EH, Feng Z, Frank J, Grigorieff N, Jiang W, Ludtke SJ, Medalia O, Penczek PA, Rosenthal PB, Rossmann MG, Schmid MF, Schröder GF, Steven AC, Stokes DL, Westbrook JD, Wriggers W, Yang H, Young J, Berman HM, Chiu W, Kleywegt GJ, Lawson CL. Outcome of the first electron microscopy validation task force meeting. Structure. 2012 Feb 08; 20(2):205-14. PMID: 22325770.
      Citations: 169     Fields:    Translation:HumansAnimalsCells
    48. Cong Y, Schröder GF, Meyer AS, Jakana J, Ma B, Dougherty MT, Schmid MF, Reissmann S, Levitt M, Ludtke SL, Frydman J, Chiu W. Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle. EMBO J. 2012 Feb 01; 31(3):720-30. PMID: 22045336.
      Citations: 34     Fields:    Translation:Cells
    49. Ludtke SJ, Tran TP, Ngo QT, Moiseenkova-Bell VY, Chiu W, Serysheva II. Flexible architecture of IP3R1 by Cryo-EM. Structure. 2011 Aug 10; 19(8):1192-9. PMID: 21827954.
      Citations: 41     Fields:    Translation:AnimalsCells
    50. Yuan S, Yu X, Asara JM, Heuser JE, Ludtke SJ, Akey CW. The holo-apoptosome: activation of procaspase-9 and interactions with caspase-3. Structure. 2011 Aug 10; 19(8):1084-96. PMID: 21827945.
      Citations: 36     Fields:    Translation:HumansCells
    51. Yuan S, Yu X, Topf M, Dorstyn L, Kumar S, Ludtke SJ, Akey CW. Structure of the Drosophila apoptosome at 6.9 å resolution. Structure. 2011 Jan 12; 19(1):128-40. PMID: 21220123.
      Citations: 33     Fields:    Translation:AnimalsCells
    52. Ludtke SJ, Lawson CL, Kleywegt GJ, Berman HM, Chiu W. Workshop on the validation and modeling of electron cryo-microscopy structures of biological nanomachines. Pac Symp Biocomput. 2011; 369-73. PMID: 21121065.
      Citations: 2     Fields:    
    53. Baird NJ, Ludtke SJ, Khant H, Chiu W, Pan T, Sosnick TR. Discrete structure of an RNA folding intermediate revealed by cryo-electron microscopy. J Am Chem Soc. 2010 Nov 24; 132(46):16352-3. PMID: 21038867.
      Citations: 10     Fields:    Translation:Cells
    54. Lawson CL, Baker ML, Best C, Bi C, Dougherty M, Feng P, van Ginkel G, Devkota B, Lagerstedt I, Ludtke SJ, Newman RH, Oldfield TJ, Rees I, Sahni G, Sala R, Velankar S, Warren J, Westbrook JD, Henrick K, Kleywegt GJ, Berman HM, Chiu W. EMDataBank.org: unified data resource for CryoEM. Nucleic Acids Res. 2011 Jan; 39(Database issue):D456-64. PMID: 20935055.
      Citations: 99     Fields:    
    55. Baker ML, Zhang J, Ludtke SJ, Chiu W. Cryo-EM of macromolecular assemblies at near-atomic resolution. Nat Protoc. 2010 Sep; 5(10):1697-708. PMID: 20885381.
      Citations: 40     Fields:    Translation:Cells
    56. Serysheva II, Ludtke SJ. 3D Structure of IP(3) Receptor. Curr Top Membr. 2010; 66:171-89. PMID: 22353480.
      Citations: 6     Fields:    
    57. Yuan S, Yu X, Topf M, Ludtke SJ, Wang X, Akey CW. Structure of an apoptosome-procaspase-9 CARD complex. Structure. 2010 May 12; 18(5):571-83. PMID: 20462491.
      Citations: 54     Fields:    Translation:Humans
    58. Cong Y, Baker ML, Jakana J, Woolford D, Miller EJ, Reissmann S, Kumar RN, Redding-Johanson AM, Batth TS, Mukhopadhyay A, Ludtke SJ, Frydman J, Chiu W. 4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):4967-72. PMID: 20194787.
      Citations: 74     Fields:    Translation:AnimalsCells
    59. Zhang J, Baker ML, Schröder GF, Douglas NR, Reissmann S, Jakana J, Dougherty M, Fu CJ, Levitt M, Ludtke SJ, Frydman J, Chiu W. Mechanism of folding chamber closure in a group II chaperonin. Nature. 2010 Jan 21; 463(7279):379-83. PMID: 20090755.
      Citations: 96     Fields:    Translation:Cells
    60. Cong Y, Ludtke SJ. Single particle analysis at high resolution. Methods Enzymol. 2010; 482:211-35. PMID: 20888963.
      Citations: 17     Fields:    
    61. Ludtke SJ. 3-D structures of macromolecules using single-particle analysis in EMAN. Methods Mol Biol. 2010; 673:157-73. PMID: 20835797.
      Citations: 37     Fields:    
    62. Ren G, Rudenko G, Ludtke SJ, Deisenhofer J, Chiu W, Pownall HJ. Model of human low-density lipoprotein and bound receptor based on cryoEM. Proc Natl Acad Sci U S A. 2010 Jan 19; 107(3):1059-64. PMID: 20080547.
      Citations: 36     Fields:    Translation:HumansCells
    63. Han M, Mei Y, Khant H, Ludtke SJ. Characterization of antibiotic peptide pores using cryo-EM and comparison to neutron scattering. Biophys J. 2009 Jul 08; 97(1):164-72. PMID: 19580754.
      Citations: 8     Fields:    Translation:Animals
    64. Cong Y, Zhang Q, Woolford D, Schweikardt T, Khant H, Dougherty M, Ludtke SJ, Chiu W, Decker H. Structural mechanism of SDS-induced enzyme activity of scorpion hemocyanin revealed by electron cryomicroscopy. Structure. 2009 May 13; 17(5):749-58. PMID: 19446530.
      Citations: 23     Fields:    Translation:AnimalsCells
    65. Zhang R, Hu X, Khant H, Ludtke SJ, Chiu W, Schmid MF, Frieden C, Lee JM. Interprotofilament interactions between Alzheimer's Abeta1-42 peptides in amyloid fibrils revealed by cryoEM. Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12):4653-8. PMID: 19264960.
      Citations: 48     Fields:    Translation:HumansCells
    66. Han M, Gillard BK, Courtney HS, Ward K, Rosales C, Khant H, Ludtke SJ, Pownall HJ. Disruption of human plasma high-density lipoproteins by streptococcal serum opacity factor requires labile apolipoprotein A-I. Biochemistry. 2009 Feb 24; 48(7):1481-7. PMID: 19191587.
      Citations: 17     Fields:    Translation:HumansCells
    67. Serysheva II, Ludtke SJ, Baker ML, Cong Y, Topf M, Eramian D, Sali A, Hamilton SL, Chiu W. Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel. Proc Natl Acad Sci U S A. 2008 Jul 15; 105(28):9610-5. PMID: 18621707.
      Citations: 58     Fields:    Translation:Cells
    68. Booth CR, Meyer AS, Cong Y, Topf M, Sali A, Ludtke SJ, Chiu W, Frydman J. Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT. Nat Struct Mol Biol. 2008 Jul; 15(7):746-53. PMID: 18536725.
      Citations: 38     Fields:    Translation:AnimalsCells
    69. Ludtke SJ, Baker ML, Chen DH, Song JL, Chuang DT, Chiu W. De novo backbone trace of GroEL from single particle electron cryomicroscopy. Structure. 2008 Mar; 16(3):441-8. PMID: 18334219.
      Citations: 95     Fields:    Translation:Cells
    70. Ménétret JF, Schaletzky J, Clemons WM, Osborne AR, Skånland SS, Denison C, Gygi SP, Kirkpatrick DS, Park E, Ludtke SJ, Rapoport TA, Akey CW. Ribosome binding of a single copy of the SecY complex: implications for protein translocation. Mol Cell. 2007 Dec 28; 28(6):1083-92. PMID: 18158904.
      Citations: 45     Fields:    Translation:Cells
    71. Serysheva II, Chiu W, Ludtke SJ. Single-particle electron cryomicroscopy of the ion channels in the excitation-contraction coupling junction. Methods Cell Biol. 2007; 79:407-35. PMID: 17327167.
      Citations: 6     Fields:    Translation:AnimalsCells
    72. Chen DH, Song JL, Chuang DT, Chiu W, Ludtke SJ. An expanded conformation of single-ring GroEL-GroES complex encapsulates an 86 kDa substrate. Structure. 2006 Nov; 14(11):1711-22. PMID: 17098196.
      Citations: 34     Fields:    Translation:HumansCells
    73. Jiang X, Jayaram H, Kumar M, Ludtke SJ, Estes MK, Prasad BV. Cryoelectron microscopy structures of rotavirus NSP2-NSP5 and NSP2-RNA complexes: implications for genome replication. J Virol. 2006 Nov; 80(21):10829-35. PMID: 16928740.
      Citations: 30     Fields:    Translation:Cells
    74. Hohn M, Tang G, Goodyear G, Baldwin PR, Huang Z, Penczek PA, Yang C, Glaeser RM, Adams PD, Ludtke SJ. SPARX, a new environment for Cryo-EM image processing. J Struct Biol. 2007 Jan; 157(1):47-55. PMID: 16931051.
      Citations: 202     Fields:    
    75. Tang G, Peng L, Baldwin PR, Mann DS, Jiang W, Rees I, Ludtke SJ. EMAN2: an extensible image processing suite for electron microscopy. J Struct Biol. 2007 Jan; 157(1):38-46. PMID: 16859925.
      Citations: 1175     Fields:    Translation:Cells
    76. Araç D, Chen X, Khant HA, Ubach J, Ludtke SJ, Kikkawa M, Johnson AE, Chiu W, Südhof TC, Rizo J. Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat Struct Mol Biol. 2006 Mar; 13(3):209-17. PMID: 16491093.
      Citations: 123     Fields:    Translation:AnimalsCells
    77. Passmore LA, Booth CR, Vénien-Bryan C, Ludtke SJ, Fioretto C, Johnson LN, Chiu W, Barford D. Structural analysis of the anaphase-promoting complex reveals multiple active sites and insights into polyubiquitylation. Mol Cell. 2005 Dec 22; 20(6):855-66. PMID: 16364911.
      Citations: 34     Fields:    Translation:Cells
    78. Yu X, Acehan D, Ménétret JF, Booth CR, Ludtke SJ, Riedl SJ, Shi Y, Wang X, Akey CW. A structure of the human apoptosome at 12.8 A resolution provides insights into this cell death platform. Structure. 2005 Nov; 13(11):1725-35. PMID: 16271896.
      Citations: 49     Fields:    Translation:HumansCells
    79. Jiang W, Ludtke SJ. Electron cryomicroscopy of single particles at subnanometer resolution. Curr Opin Struct Biol. 2005 Oct; 15(5):571-7. PMID: 16140524.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    80. Ludtke SJ, Serysheva II, Hamilton SL, Chiu W. The pore structure of the closed RyR1 channel. Structure. 2005 Aug; 13(8):1203-11. PMID: 16084392.
      Citations: 64     Fields:    Translation:AnimalsCells
    81. Sitharaman B, Kissell KR, Hartman KB, Tran LA, Baikalov A, Rusakova I, Sun Y, Khant HA, Ludtke SJ, Chiu W, Laus S, Tóth E, Helm L, Merbach AE, Wilson LJ. Superparamagnetic gadonanotubes are high-performance MRI contrast agents. Chem Commun (Camb). 2005 Aug 21; (31):3915-7. PMID: 16075070.
      Citations: 61     Fields:    
    82. Ménétret JF, Hegde RS, Heinrich SU, Chandramouli P, Ludtke SJ, Rapoport TA, Akey CW. Architecture of the ribosome-channel complex derived from native membranes. J Mol Biol. 2005 Apr 29; 348(2):445-57. PMID: 15811380.
      Citations: 45     Fields:    Translation:AnimalsCells
    83. Serysheva II, Hamilton SL, Chiu W, Ludtke SJ. Structure of Ca2+ release channel at 14 A resolution. J Mol Biol. 2005 Jan 21; 345(3):427-31. PMID: 15581887.
      Citations: 32     Fields:    Translation:Cells
    84. Booth CR, Jiang W, Baker ML, Zhou ZH, Ludtke SJ, Chiu W. A 9 angstroms single particle reconstruction from CCD captured images on a 200 kV electron cryomicroscope. J Struct Biol. 2004 Aug; 147(2):116-27. PMID: 15193640.
      Citations: 24     Fields:    Translation:Cells
    85. Mao Y, Vyas NK, Vyas MN, Chen DH, Ludtke SJ, Chiu W, Quiocho FA. Structure of the bifunctional and Golgi-associated formiminotransferase cyclodeaminase octamer. EMBO J. 2004 Aug 04; 23(15):2963-71. PMID: 15272307.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    86. Ludtke SJ, Chen DH, Song JL, Chuang DT, Chiu W. Seeing GroEL at 6 A resolution by single particle electron cryomicroscopy. Structure. 2004 Jul; 12(7):1129-36. PMID: 15242589.
      Citations: 63     Fields:    Translation:Cells
    87. Chen C, Ko Y, Delannoy M, Ludtke SJ, Chiu W, Pedersen PL. Mitochondrial ATP synthasome: three-dimensional structure by electron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP. J Biol Chem. 2004 Jul 23; 279(30):31761-8. PMID: 15166242.
      Citations: 76     Fields:    Translation:AnimalsCells
    88. Brink J, Ludtke SJ, Kong Y, Wakil SJ, Ma J, Chiu W. Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis. Structure. 2004 Feb; 12(2):185-91. PMID: 14962379.
      Citations: 32     Fields:    Translation:HumansCells
    89. Zhu Y, Carragher B, Glaeser RM, Fellmann D, Bajaj C, Bern M, Mouche F, de Haas F, Hall RJ, Kriegman DJ, Ludtke SJ, Mallick SP, Penczek PA, Roseman AM, Sigworth FJ, Volkmann N, Potter CS. Automatic particle selection: results of a comparative study. J Struct Biol. 2004 Jan-Feb; 145(1-2):3-14. PMID: 15065668.
      Citations: 35     Fields:    Translation:AnimalsCells
    90. Ludtke SJ, Nason L, Tu H, Peng L, Chiu W. Object oriented database and electronic notebook for transmission electron microscopy. Microsc Microanal. 2003 Dec; 9(6):556-65. PMID: 14750990.
      Citations: 6     Fields:    
    91. Ludtke SJ, Chiu W. Focal pair merging for contrast enhancement of single particles. J Struct Biol. 2003 Oct-Nov; 144(1-2):73-8. PMID: 14643210.
      Citations: 5     Fields:    
    92. Serysheva II, Bare DJ, Ludtke SJ, Kettlun CS, Chiu W, Mignery GA. Structure of the type 1 inositol 1,4,5-trisphosphate receptor revealed by electron cryomicroscopy. J Biol Chem. 2003 Jun 13; 278(24):21319-22. PMID: 12714606.
      Citations: 34     Fields:    Translation:AnimalsCells
    93. Baker ML, Serysheva II, Sencer S, Wu Y, Ludtke SJ, Jiang W, Hamilton SL, Chiu W. The skeletal muscle Ca2+ release channel has an oxidoreductase-like domain. Proc Natl Acad Sci U S A. 2002 Sep 17; 99(19):12155-60. PMID: 12218169.
      Citations: 21     Fields:    Translation:AnimalsCells
    94. Serysheva II, Ludtke SJ, Baker MR, Chiu W, Hamilton SL. Structure of the voltage-gated L-type Ca2+ channel by electron cryomicroscopy. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10370-5. PMID: 12149473.
      Citations: 26     Fields:    Translation:AnimalsCells
    95. Brink J, Ludtke SJ, Yang CY, Gu ZW, Wakil SJ, Chiu W. Quaternary structure of human fatty acid synthase by electron cryomicroscopy. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):138-43. PMID: 11756679.
      Citations: 16     Fields:    Translation:HumansCells
    96. Ludtke SJ, Jakana J, Song JL, Chuang DT, Chiu W. A 11.5 A single particle reconstruction of GroEL using EMAN. J Mol Biol. 2001 Nov 23; 314(2):253-62. PMID: 11718559.
      Citations: 54     Fields:    Translation:Cells
    97. Jiang W, Baker ML, Ludtke SJ, Chiu W. Bridging the information gap: computational tools for intermediate resolution structure interpretation. J Mol Biol. 2001 May 18; 308(5):1033-44. PMID: 11352589.
      Citations: 105     Fields:    Translation:Cells
    98. Saad A, Ludtke SJ, Jakana J, Rixon FJ, Tsuruta H, Chiu W. Fourier amplitude decay of electron cryomicroscopic images of single particles and effects on structure determination. J Struct Biol. 2001 Jan; 133(1):32-42. PMID: 11356062.
      Citations: 35     Fields:    Translation:Cells
    99. Ludtke SJ, Baldwin PR, Chiu W. EMAN: semiautomated software for high-resolution single-particle reconstructions. J Struct Biol. 1999 Dec 01; 128(1):82-97. PMID: 10600563.
      Citations: 1236     Fields:    Translation:Cells
    100. Heller WT, He K, Ludtke SJ, Harroun TA, Huang HW. Effect of changing the size of lipid headgroup on peptide insertion into membranes. Biophys J. 1997 Jul; 73(1):239-44. PMID: 9199788.
      Citations: 30     Fields:    Translation:Cells
    101. He K, Ludtke SJ, Heller WT, Huang HW. Mechanism of alamethicin insertion into lipid bilayers. Biophys J. 1996 Nov; 71(5):2669-79. PMID: 8913604.
      Citations: 65     Fields:    Translation:Cells
    102. Ludtke SJ, He K, Heller WT, Harroun TA, Yang L, Huang HW. Membrane pores induced by magainin. Biochemistry. 1996 Oct 29; 35(43):13723-8. PMID: 8901513.
      Citations: 194     Fields:    Translation:AnimalsCells
    103. He K, Ludtke SJ, Worcester DL, Huang HW. Neutron scattering in the plane of membranes: structure of alamethicin pores. Biophys J. 1996 Jun; 70(6):2659-66. PMID: 8744303.
      Citations: 79     Fields:    Translation:Cells
    104. Ludtke S, He K, Huang H. Membrane thinning caused by magainin 2. Biochemistry. 1995 Dec 26; 34(51):16764-9. PMID: 8527451.
      Citations: 99     Fields:    Translation:AnimalsCells
    105. He K, Ludtke SJ, Huang HW, Worcester DL. Antimicrobial peptide pores in membranes detected by neutron in-plane scattering. Biochemistry. 1995 Dec 05; 34(48):15614-8. PMID: 7495788.
      Citations: 48     Fields:    Translation:Cells
    106. Wu Y, He K, Ludtke SJ, Huang HW. X-ray diffraction study of lipid bilayer membranes interacting with amphiphilic helical peptides: diphytanoyl phosphatidylcholine with alamethicin at low concentrations. Biophys J. 1995 Jun; 68(6):2361-9. PMID: 7647240.
      Citations: 54     Fields:    Translation:Cells
    107. Ludtke SJ, He K, Wu Y, Huang HW. Cooperative membrane insertion of magainin correlated with its cytolytic activity. Biochim Biophys Acta. 1994 Feb 23; 1190(1):181-4. PMID: 8110813.
      Citations: 43     Fields:    Translation:Cells
    108. He K, Ludtke SJ, Wu Y, Huang HW, Andersen OS, Greathouse D, Koeppe RE. Closed state of gramicidin channel detected by X-ray in-plane scattering. Biophys Chem. 1994 Feb; 49(1):83-9. PMID: 7510532.
      Citations: 12     Fields:    Translation:Cells
    109. He K, Ludtke SJ, Wu Y, Huang HW. X-ray scattering with momentum transfer in the plane of membrane. Application to gramicidin organization. Biophys J. 1993 Jan; 64(1):157-62. PMID: 7679294.
      Citations: 12     Fields:    
    LUDTKE's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (344)
    Explore
    _
    Co-Authors (17)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _