TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    R01 HD082786     (Bert W. O'Malley)Apr 1, 2014 - Mar 31, 2020
    The ERbeta/SRC-1 isoform complex drives endometriosis progression
    Role: Co-PI

    U24 DK097748     (Bert W. O'Malley)Sep 1, 2015 - Aug 31, 2018
    Identification of Nuclear Receptor Genomic Network that Links Endometriosis to Birth Defects
    Role: Pilot Project PI

    R01HD098059     (HAN, SANG JUN JUN)Mar 6, 2020 - Dec 31, 2024
    The Genomic Function of Estrogen Receptor Beta in Endometriosis
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gilad Y, Eliaz Y, Yu Y, Dean AM, Han SJ, Qin L, O'Malley BW, Lonard DM. A genome-scale CRISPR Cas9 dropout screen identifies synthetically lethal targets in SRC-3 inhibited cancer cells. Commun Biol. 2021 03 25; 4(1):399. PMID: 33767353.
      Citations:    Translation:HumansCells
    2. Mohankumar K, Li X, Sung N, Cho YJ, Han SJ, Safe S. Bis-Indole-Derived Nuclear Receptor 4A1 (NR4A1, Nur77) Ligands as Inhibitors of Endometriosis. Endocrinology. 2020 04 01; 161(4). PMID: 32099996.
      Citations: 1     Fields:    Translation:Animals
    3. Han SJ, Lee JE, Cho YJ, Park MJ, O'Malley BW. Genomic Function of Estrogen Receptor ß in Endometriosis. Endocrinology. 2019 11 01; 160(11):2495-2516. PMID: 31504401.
      Citations: 6     Fields:    Translation:HumansAnimals
    4. Gilad Y, Eliaz Y, Yu Y, Han SJ, O'Malley BW, Lonard DM. Drug-induced PD-L1 expression and cell stress response in breast cancer cells can be balanced by drug combination. Sci Rep. 2019 10 22; 9(1):15099. PMID: 31641154.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    5. Cho YJ, Lee JE, Park MJ, O'Malley BW, Han SJ. Bufalin suppresses endometriosis progression by inducing pyroptosis and apoptosis. J Endocrinol. 2018 06; 237(3):255-269. PMID: 29636364.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    6. Cho YJ, Lee SH, Park JW, Han M, Park MJ, Han SJ. Dysfunctional signaling underlying endometriosis: current state of knowledge. J Mol Endocrinol. 2018 04; 60(3):R97-R113. PMID: 29330150.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    7. Han SJ, Jung SY, Wu SP, Hawkins SM, Park MJ, Kyo S, Qin J, Lydon JP, Tsai SY, Tsai MJ, DeMayo FJ, O'Malley BW. Estrogen Receptor ß Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 2015 Nov 05; 163(4):960-74. PMID: 26544941.
      Citations: 84     Fields:    Translation:HumansAnimals
    8. Han SJ, Begum K, Foulds CE, Hamilton RA, Bailey S, Malovannaya A, Chan D, Qin J, O'Malley BW. The Dual Estrogen Receptor a Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety. Mol Pharmacol. 2016 Jan; 89(1):14-26. PMID: 26487511.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    9. Han SJ, O'Malley BW. The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis. Hum Reprod Update. 2014 Jul-Aug; 20(4):467-84. PMID: 24634322.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    10. Liu S, Han SJ, Smith CL. Cooperative activation of gene expression by agonists and antagonists mediated by estrogen receptor heteroligand dimer complexes. Mol Pharmacol. 2013 May; 83(5):1066-77. PMID: 23462505.
      Citations: 7     Fields:    Translation:HumansCells
    11. Han SJ, Hawkins SM, Begum K, Jung SY, Kovanci E, Qin J, Lydon JP, DeMayo FJ, O'Malley BW. A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med. 2012 Jul; 18(7):1102-11. PMID: 22660634.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    12. Zhang L, Zhang B, Han SJ, Shore AN, Rosen JM, Demayo FJ, Xin L. Targeting CreER(T2) expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis. Transgenic Res. 2012 Oct; 21(5):1117-23. PMID: 22350718.
      Citations: 12     Fields:    Translation:AnimalsCells
    13. Han SJ, O'Malley BW, DeMayo FJ. An estrogen receptor alpha activity indicator model in mice. Genesis. 2009 Dec; 47(12):815-24. PMID: 19882671.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    14. Han SJ, Lonard DM, O'Malley BW. Multi-modulation of nuclear receptor coactivators through posttranslational modifications. Trends Endocrinol Metab. 2009 Jan; 20(1):8-15. PMID: 19019695.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    15. Jeong JW, Lee KY, Han SJ, Aronow BJ, Lydon JP, O'Malley BW, DeMayo FJ. The p160 steroid receptor coactivator 2, SRC-2, regulates murine endometrial function and regulates progesterone-independent and -dependent gene expression. Endocrinology. 2007 Sep; 148(9):4238-50. PMID: 17556502.
      Citations: 30     Fields:    Translation:Animals
    16. Han SJ, Tsai SY, Tsai MJ, O'Malley BW. Distinct temporal and spatial activities of RU486 on progesterone receptor function in reproductive organs of ovariectomized mice. Endocrinology. 2007 May; 148(5):2471-86. PMID: 17303655.
      Citations: 12     Fields:    Translation:AnimalsCells
    17. Han SJ, DeMayo FJ, O'Malley BW. Dynamic regulation of progesterone receptor activity in female reproductive tissues. Ernst Schering Found Symp Proc. 2007; (1):25-43. PMID: 18543433.
      Citations: 4     Fields:    Translation:HumansAnimals
    18. Han SJ, Jung SY, Malovannaya A, Kim T, Lanz RB, Qin J, O'Malley BW. A scoring system for the follow up study of nuclear receptor coactivator complexes. Nucl Recept Signal. 2006; 4:e014. PMID: 16862220.
      Citations: 5     Fields:    
    19. Han SJ, DeMayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol. 2006 Jan; 20(1):45-55. PMID: 16141356.
      Citations: 41     Fields:    Translation:AnimalsCells
    20. Han SJ, Jeong J, Demayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice. Mol Cell Biol. 2005 Sep; 25(18):8150-65. PMID: 16135805.
      Citations: 17     Fields:    Translation:AnimalsCells
    21. Ye X, Han SJ, Tsai SY, DeMayo FJ, Xu J, Tsai MJ, O'Malley BW. Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9487-92. PMID: 15983373.
      Citations: 19     Fields:    Translation:Animals
    22. Kang JS, Kim SH, Hwang MS, Han SJ, Lee YC, Kim YJ. The structural and functional organization of the yeast mediator complex. J Biol Chem. 2001 Nov 09; 276(45):42003-10. PMID: 11555651.
      Citations: 70     Fields:    Translation:AnimalsCells
    23. Han SJ, Lee JS, Kang JS, Kim YJ. Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes. J Biol Chem. 2001 Oct 05; 276(40):37020-6. PMID: 11470794.
      Citations: 21     Fields:    Translation:AnimalsCells
    24. Park JM, Kim HS, Han SJ, Hwang MS, Lee YC, Kim YJ. In vivo requirement of activator-specific binding targets of mediator. Mol Cell Biol. 2000 Dec; 20(23):8709-19. PMID: 11073972.
      Citations: 63     Fields:    Translation:AnimalsCells
    25. Kwon JY, Park JM, Gim BS, Han SJ, Lee J, Kim YJ. Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):14990-5. PMID: 10611325.
      Citations: 18     Fields:    Translation:AnimalsCells
    26. Lee YC, Park JM, Min S, Han SJ, Kim YJ. An activator binding module of yeast RNA polymerase II holoenzyme. Mol Cell Biol. 1999 Apr; 19(4):2967-76. PMID: 10082564.
      Citations: 73     Fields:    Translation:AnimalsCells
    27. Han SJ, Lee YC, Gim BS, Ryu GH, Park SJ, Lane WS, Kim YJ. Activator-specific requirement of yeast mediator proteins for RNA polymerase II transcriptional activation. Mol Cell Biol. 1999 Feb; 19(2):979-88. PMID: 9891034.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    28. Han SJ, Lee BJ, Kang HS. Purification and characterization of the nuclear ribonuclease P of Aspergillus nidulans. Eur J Biochem. 1998 Jan 15; 251(1-2):244-51. PMID: 9492290.
      Citations: 3     Fields:    Translation:AnimalsCells
    29. Han SJ, Kang HS. Purification and characterization of the precursor tRNA 3'-end processing nuclease from Aspergillus nidulans. Biochem Biophys Res Commun. 1997 Apr 17; 233(2):354-8. PMID: 9144538.
      Citations: 6     Fields:    Translation:AnimalsCells
    30. Han SJ, Yoo YJ, Kang HS. Characterization of a bifunctional cellulase and its structural gene. The cell gene of Bacillus sp. D04 has exo- and endoglucanase activity. J Biol Chem. 1995 Oct 27; 270(43):26012-9. PMID: 7592793.
      Citations: 15     Fields:    Translation:Cells
    HAN's Networks
    Click the
    buttons for more information and interactive visualizations!
    Concepts (193)
    Co-Authors (16)
    Similar People (60)
    Same Department Expand Description
    Physical Neighbors