RICHARD FINNELL

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
Address6501 Fannin St
Houston, TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Precision Environmental Health
    DivisionCenter for Precision Env Health

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-General Medicine


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    R03MH042149     (FINNELL, RICHARD H.)Aug 1, 1986 - Jul 31, 1987
    NIH/NIMH
    HEAT SHOCK PROTEINS AND ABNORMAL NEURAL DEVELOPMENT
    Role: Principal Investigator

    R01ES004326     (FINNELL, RICHARD H.)Jan 15, 1988 - Jun 30, 1991
    NIH/NIEHS
    THE HEAT SHOCK RESPONSE: POTENTIAL TO SCREEN TERATOGENS
    Role: Principal Investigator

    R01DE011303     (FINNELL, RICHARD H.)May 1, 1994 - Apr 30, 1999
    NIH/NIDCR
    ANTIEPILETIC DRUG SYNDROME--A MOLECULAR ANALYSIS
    Role: Principal Investigator

    R01ES007165     (FINNELL, RICHARD H.)Jul 1, 1994 - Jun 30, 1998
    NIH/NIEHS
    GENE EXPRESSION DURING MURINE NEURAL TUBE CLOSURE
    Role: Principal Investigator

    R01HD035396     (FINNELL, RICHARD H.)Apr 1, 1997 - Mar 31, 2002
    NIH/NICHD
    FOLATE RECEPTOR KNOCKOUTS, ARSENATE AND BIRTH DEFECTS
    Role: Principal Investigator

    R01DE013613     (FINNELL, RICHARD H.)May 1, 1999 - Apr 30, 2004
    NIH/NIDCR
    FOLATE RECEPTORS IN CRANIOFACIAL MALFORMATIONS
    Role: Principal Investigator

    R01DE016315     (FINNELL, RICHARD H.)Aug 1, 2005 - Oct 30, 2010
    NIH/NIDCR
    GENETIC REGULATION OF FOLATE RESPONSIVE BIRTH DEFECTS
    Role: Principal Investigator

    R13NS066584     (FINNELL, RICHARD H.)Jul 1, 2009 - Jun 30, 2010
    NIH/NINDS
    Sixth International Neural Tube Defects Conference
    Role: Principal Investigator

    U13DP003269     (FINNELL, RICHARD H.)Sep 30, 2011 - Sep 29, 2016
    CDC/NCCDPHP
    7TH INTERNATIONAL CONFERENCE ON NEURAL TUBE DEFECTS (NTDS)
    Role: Principal Investigator

    R21HD072251     (FINNELL, RICHARD H.)Aug 1, 2012 - Jul 31, 2014
    NIH/NICHD
    Genetic Regulation of Valproic Acid Teratogenicity
    Role: Principal Investigator

    R01ES021006     (FINNELL, RICHARD H.)Aug 16, 2012 - Jun 30, 2015
    NIH/NIEHS
    Study of Neural Tube Defects Etiology: Genome and Exposome
    Role: Principal Investigator

    R13HD084156     (FINNELL, RICHARD H.)Aug 1, 2015 - Jul 31, 2016
    NIH/NICHD
    2015 International Conference on Neural Tube Defects
    Role: Principal Investigator

    R01HD081216     (FINNELL, RICHARD H.)Aug 10, 2015 - Jun 30, 2020
    NIH/NICHD
    Folic Acid, Parental Mutation Rates and the Risk for Neural Tube Defects
    Role: Principal Investigator

    R01HD083809     (FINNELL, RICHARD H.)Feb 15, 2016 - Jan 31, 2021
    NIH/NICHD
    INTERVENTION STRATEGIES FOR NON-FOLATE RESPONSIVE NEURAL TUBE DEFECTS
    Role: Principal Investigator

    R13HD093414     (FINNELL, RICHARD H.)Jul 16, 2017 - Jun 30, 2018
    NIH/NICHD
    2017 10th International Conference on Neural Tube Defects
    Role: Principal Investigator

    R01HD093758     (FINNELL, RICHARD H.)Sep 1, 2018 - Jun 30, 2023
    NIH/NICHD
    The Role of GPR161 in the Etiology of Neural Tube Defects
    Role: Principal Investigator

    R01HD095520     (LARIN, KIRILL V)Sep 1, 2018 - Jun 30, 2023
    NIH/NICHD
    Biomechanics of Neural Tube Development using Brillouin-OCT Multimodality
    Role: Co-Principal Investigator

    R01HD098131     (PARCHEM, RONALD J)Mar 10, 2020 - Feb 28, 2025
    NIH/NICHD
    MicroRNA regulation of neural tube closure
    Role: Co-Principal Investigator

    R01HD100535     (LEI, YUNPING)Mar 10, 2020 - Feb 28, 2025
    NIH/NICHD
    Role of Slc25a32 and Its Interaction with Lrp6 in the Etiology of Neural Tube Defects
    Role: Co-Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Keuls RA, Kojima K, Lozzi B, Steele JW, Chen Q, Gross SS, Finnell RH, Parchem RJ. MiR-302 Regulates Glycolysis to Control Cell-Cycle during Neural Tube Closure. Int J Mol Sci. 2020 Oct 13; 21(20). PMID: 33066028.
      Citations:    Fields:    
    2. Maruvada P, Stover PJ, Mason JB, Bailey RL, Davis CD, Field MS, Finnell RH, Garza C, Green R, Gueant JL, Jacques PF, Klurfeld DM, Lamers Y, MacFarlane AJ, Miller JW, Molloy AM, O'Connor DL, Pfeiffer CM, Potischman NA, Rodricks JV, Rosenberg IH, Ross SA, Shane B, Selhub J, Stabler SP, Trasler J, Yamini S, Zappalà G. Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop. Am J Clin Nutr. 2020 Oct 06. PMID: 33022704.
      Citations:    Fields:    
    3. Tian T, Cao X, Kim SE, Lin YL, Steele JW, Cabrera RM, Karki M, Yang W, Marini NJ, Hoffman EN, Han X, Hu C, Wang L, Wlodarczyk BJ, Shaw GM, Ren A, Finnell RH, Lei Y. FKBP8 variants are risk factors for spina bifida. Hum Mol Genet. 2020 Sep 24. PMID: 32969478.
      Citations:    Fields:    
    4. Cao X, Wolf A, Kim SE, Cabrera RM, Wlodarczyk BJ, Zhu H, Parker M, Lin Y, Steele JW, Han X, Ramaekers VT, Steinfeld R, Finnell RH, Lei Y. CIC de novo loss of function variants contribute to cerebral folate deficiency by downregulating FOLR1 expression. J Med Genet. 2020 Aug 20. PMID: 32820034.
      Citations:    Fields:    
    5. Lei Y, Ludorf KL, Yu X, Benjamin RH, Gu X, Lin Y, Finnell RH, Mitchell LE, Musfee FI, Malik S, Canfield MA, Morrison AC, Hobbs CA, Van Zutphen AR, Fisher S, Agopian AJ. Maternal hypertension-related genotypes and congenital heart defects. Am J Hypertens. 2020 Jul 25. PMID: 32710738.
      Citations:    Fields:    
    6. Liu L, Liu W, Shi Y, Li L, Gao Y, Lei Y, Finnell R, Zhang T, Zhang F, Jin L, Li H, Tao W, Wang H. DVL mutations identified from human neural tube defects and Dandy-Walker malformation obstruct the Wnt signaling pathway. J Genet Genomics. 2020 Jun 20; 47(6):301-310. PMID: 32900645.
      Citations:    Fields:    
    7. Taiwo TE, Cao X, Cabrera RM, Lei Y, Finnell RH. Approaches to studying the genomic architecture of complex birth defects. Prenat Diagn. 2020 May 28. PMID: 32468575.
      Citations:    Fields:    
    8. Shaw GM, Yang W, Finnell RH. Male-to-female ratios among NTDs and women's periconceptional intake of folic acid. Birth Defects Res. 2020 Oct; 112(16):1187-1193. PMID: 32415919.
      Citations:    Fields:    
    9. Tian T, Lei Y, Chen Y, Guo Y, Jin L, Finnell RH, Wang L, Ren A. Rare copy number variations of planar cell polarity genes are associated with human neural tube defects. Neurogenetics. 2020 Jul; 21(3):217-225. PMID: 32388773.
      Citations:    Fields:    
    10. Tian T, Lei Y, Chen Y, Karki M, Jin L, Finnell RH, Wang L, Ren A. Somatic mutations in planar cell polarity genes in neural tissue from human fetuses with neural tube defects. Hum Genet. 2020 Oct; 139(10):1299-1314. PMID: 32356230.
      Citations:    Fields:    Translation:HumansAnimalsCells
    11. Steele JW, Kim SE, Finnell RH. One-carbon metabolism and folate transporter genes: Do they factor prominently in the genetic etiology of neural tube defects? Biochimie. 2020 Jun; 173:27-32. PMID: 32061804.
      Citations:    Fields:    
    12. Lei Y, Finnell RH. New myotonic dystrophy type 1 mouse model. Cell Res. 2020 02; 30(2):99-100. PMID: 31953529.
      Citations:    Fields:    Translation:Animals
    13. Mei X, Qi D, Zhang T, Zhao Y, Jin L, Hou J, Wang J, Lin Y, Xue Y, Zhu P, Liu Z, Huang L, Nie J, Si W, Ma J, Ye J, Finnell RH, Saiyin H, Wang H, Zhao J, Zhao S, Xu W. Inhibiting MARSs reduces hyperhomocysteinemia-associated neural tube and congenital heart defects. EMBO Mol Med. 2020 Mar 06; 12(3):e9469. PMID: 32003121.
      Citations: 1     Fields:    
    14. Cao X, Tian T, Steele JW, Cabrera RM, Aguiar-Pulido V, Wadhwa S, Bhavani N, Bi P, Gargurevich NH, Hoffman EN, Cai CQ, Marini NJ, Yang W, Shaw GM, Ross ME, Finnell RH, Lei Y. Loss of RAD9B impairs early neural development and contributes to the risk for human spina bifida. Hum Mutat. 2020 Apr; 41(4):786-799. PMID: 31898828.
      Citations:    Fields:    
    15. Chen Z, Lin X, Lei Y, Chen H, Finnell RH, Wang Y, Xu J, Lu D, Xie H, Chen F. Genome-wide association study in Chinese cohort identifies one novel hypospadias risk associated locus at 12q13.13. BMC Med Genomics. 2019 12 19; 12(1):196. PMID: 31856834.
      Citations: 1     Fields:    Translation:Humans
    16. Meador KJ, Pennell PB, May RC, Van Marter L, McElrath TF, Brown C, Gerard E, Kalayjian L, Gedzelman E, Penovich P, Cavitt J, French J, Hwang S, Pack AM, Sam M, Birnbaum AK, Finnell R. Fetal loss and malformations in the MONEAD study of pregnant women with epilepsy. Neurology. 2020 04 07; 94(14):e1502-e1511. PMID: 31806691.
      Citations:    Fields:    Translation:Humans
    17. Wang L, Ren A, Tian T, Li N, Cao X, Zhang P, Jin L, Li Z, Shen Y, Zhang B, Finnell RH, Lei Y. Whole-Exome Sequencing Identifies Damaging de novo Variants in Anencephalic Cases. Front Neurosci. 2019; 13:1285. PMID: 31849593.
      Citations:    
    18. Li H, Wang X, Zhao H, Wang F, Bao Y, Guo J, Chang S, Wu L, Cheng H, Chen S, Zou J, Cui X, Niswander L, Finnell RH, Wang H, Zhang T. Low folate concentration impacts mismatch repair deficiency in neural tube defects. Epigenomics. 2020 01; 12(1):5-18. PMID: 31769301.
      Citations: 2     Fields:    
    19. Cabrera RM, Souder JP, Steele JW, Yeo L, Tukeman G, Gorelick DA, Finnell RH. The antagonism of folate receptor by dolutegravir: developmental toxicity reduction by supplemental folic acid. AIDS. 2019 11 01; 33(13):1967-1976. PMID: 31259764.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    20. Chen Z, Lei Y, Zheng Y, Aguiar-Pulido V, Ross ME, Peng R, Jin L, Zhang T, Finnell RH, Wang H. Author Correction: Threshold for neural tube defect risk by accumulated singleton loss-of-function variants. Cell Res. 2019 Sep; 29(9):776. PMID: 31346254.
      Citations: 1     Fields:    
    21. López-Escobar B, Wlodarczyk BJ, Caro-Vega J, Lin Y, Finnell RH, Ybot-González P. The interaction of maternal diabetes with mutations that affect folate metabolism and how they affect the development of neural tube defects in mice. Dev Dyn. 2019 10; 248(10):900-917. PMID: 31361376.
      Citations:    Fields:    Translation:HumansAnimals
    22. Alam C, Aufreiter S, Georgiou CJ, Hoque MT, Finnell RH, O'Connor DL, Goldman ID, Bendayan R. Upregulation of reduced folate carrier by vitamin D enhances brain folate uptake in mice lacking folate receptor alpha. Proc Natl Acad Sci U S A. 2019 08 27; 116(35):17531-17540. PMID: 31405972.
      Citations: 1     Fields:    Translation:Animals
    23. Jenkins MM, Almli LM, Pangilinan F, Chong JX, Blue EE, Shapira SK, White J, McGoldrick D, Smith JD, Mullikin JC, Bean CJ, Nembhard WN, Lou XY, Shaw GM, Romitti PA, Keppler-Noreuil K, Yazdy MM, Kay DM, Carter TC, Olshan AF, Moore KJ, Nascone-Yoder N, Finnell RH, Lupo PJ, Feldkamp ML, Nickerson DA, Bamshad MJ, Brody LC, Reefhuis J. Exome sequencing of family trios from the National Birth Defects Prevention Study: Tapping into a rich resource of genetic and environmental data. Birth Defects Res. 2019 12 01; 111(20):1618-1632. PMID: 31328417.
      Citations: 1     Fields:    Translation:Humans
    24. Steele JW, Bayliss S, Bayliss J, Lin YL, Wlodarczyk BJ, Cabrera RM, Asfaw YG, Cummings TJ, Finnell RH, George TM. Heritable spina bifida in sheep: A potential model for fetal repair of myelomeningocele. J Pediatr Surg. 2020 Mar; 55(3):475-481. PMID: 31301886.
      Citations:    Fields:    Translation:Animals
    25. Kousa YA, Zhu H, Fakhouri WD, Lei Y, Kinoshita A, Roushangar RR, Patel NK, Agopian AJ, Yang W, Leslie EJ, Busch TD, Mansour TA, Li X, Smith AL, Li EB, Sharma DB, Williams TJ, Chai Y, Amendt BA, Liao EC, Mitchell LE, Bassuk AG, Gregory S, Ashley-Koch A, Shaw GM, Finnell RH, Schutte BC. The TFAP2A-IRF6-GRHL3 genetic pathway is conserved in neurulation. Hum Mol Genet. 2019 05 15; 28(10):1726-1737. PMID: 30689861.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    26. Hoang TT, Lei Y, Mitchell LE, Sharma SV, Swartz MD, Waller DK, Finnell RH, Benjamin RH, Browne ML, Canfield MA, Lupo PJ, McKenzie P, Shaw GM, Agopian AJ. Maternal genetic markers for risk of celiac disease and their potential association with neural tube defects in offspring. Mol Genet Genomic Med. 2019 06; 7(6):e688. PMID: 30968606.
      Citations:    Fields:    Translation:Humans
    27. Hoang TT, Lei Y, Mitchell LE, Sharma SV, Swartz MD, Waller DK, Finnell RH, Benjamin RH, Browne ML, Canfield MA, Lupo PJ, McKenzie P, Shaw G, Agopian AJ. Maternal Lactase Polymorphism (rs4988235) Is Associated with Neural Tube Defects in Offspring in the National Birth Defects Prevention Study. J Nutr. 2019 02 01; 149(2):295-303. PMID: 30689919.
      Citations: 1     Fields:    Translation:Humans
    28. Lei Y, Kim SE, Chen Z, Cao X, Zhu H, Yang W, Shaw GM, Zheng Y, Zhang T, Wang HY, Finnell RH. Variants identified in PTK7 associated with neural tube defects. Mol Genet Genomic Med. 2019 04; 7(4):e00584. PMID: 30689296.
      Citations: 3     Fields:    Translation:HumansCells
    29. Martin JB, Muccioli M, Herman K, Finnell RH, Plageman TF. Folic acid modifies the shape of epithelial cells during morphogenesis via a Folr1 and MLCK dependent mechanism. Biol Open. 2019 Jan 22; 8(1). PMID: 30670450.
      Citations:    
    30. Xie Y, Ma A, Wang B, Peng R, Jing Y, Wang D, Finnell RH, Qiao B, Wang Y, Wang H, Zheng Y. Rare mutations of ADAM17 from TOFs induce hypertrophy in human embryonic stem cell-derived cardiomyocytes via HB-EGF signaling. Clin Sci (Lond). 2019 01 31; 133(2):225-238. PMID: 30610007.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    31. Kim SE, Lei Y, Hwang SH, Wlodarczyk BJ, Mukhopadhyay S, Shaw GM, Ross ME, Finnell RH. Dominant negative GPR161 rare variants are risk factors of human spina bifida. Hum Mol Genet. 2019 01 15; 28(2):200-208. PMID: 30256984.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    32. Wang YM, Zheng YF, Yang SY, Yang ZM, Zhang LN, He YQ, Gong XH, Liu D, Finnell RH, Qiu ZL, Du YS, Wang HY. MicroRNA-197 controls ADAM10 expression to mediate MeCP2's role in the differentiation of neuronal progenitors. Cell Death Differ. 2019 10; 26(10):1863-1879. PMID: 30560934.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    33. Walker DI, Perry-Walker K, Finnell RH, Pennell KD, Tran V, May RC, McElrath TF, Meador KJ, Pennell PB, Jones DP. Metabolome-wide association study of anti-epileptic drug treatment during pregnancy. Toxicol Appl Pharmacol. 2019 01 15; 363:122-130. PMID: 30521819.
      Citations: 4     Fields:    Translation:Humans
    34. Avagliano L, Massa V, George TM, Qureshy S, Bulfamante GP, Finnell RH. Overview on neural tube defects: From development to physical characteristics. Birth Defects Res. 2019 11 15; 111(19):1455-1467. PMID: 30421543.
      Citations: 6     Fields:    Translation:Humans
    35. Lin YL, Bialer M, Cabrera RM, Finnell RH, Wlodarczyk BJ. Teratogenicity of valproic acid and its constitutional isomer, amide derivative valnoctamide in mice. Birth Defects Res. 2019 08 15; 111(14):1013-1023. PMID: 30325584.
      Citations:    Fields:    Translation:Animals
    36. Zhang J, Raghunathan R, Rippy J, Wu C, Finnell RH, Larin KV, Scarcelli G. Tissue biomechanics during cranial neural tube closure measured by Brillouin microscopy and optical coherence tomography. Birth Defects Res. 2019 08 15; 111(14):991-998. PMID: 30239173.
      Citations: 5     Fields:    Translation:Animals
    37. Conde-Vancells J, Vazquez-Chantada M, McCollum CW, Bondesson M, Kalasekar SM, Wlodarczyk BJ, Gustafsson JÅ, Cabrera RM, Finnell RH. Combining mouse embryonic stem cells and zebrafish embryos to evaluate developmental toxicity of chemical exposure. Reprod Toxicol. 2018 10; 81:220-228. PMID: 30103011.
      Citations:    Fields:    Translation:AnimalsCells
    38. Zhou X, Xu M, Zeng W, Chen Z, Lu G, Gong Y, Finnell RH, Xiao H, Qiao B, Wang H. Combined effects of FH (E404D) and ACOX2 (R409H) cause metabolic defects in primary cardiac malignant tumor. Cell Death Discov. 2018; 4:18. PMID: 30062063.
      Citations:    
    39. Chen Z, Lei Y, Zheng Y, Aguiar-Pulido V, Ross ME, Peng R, Jin L, Zhang T, Finnell RH, Wang H. Threshold for neural tube defect risk by accumulated singleton loss-of-function variants. Cell Res. 2018 10; 28(10):1039-1041. PMID: 29976953.
      Citations: 5     Fields:    Translation:Humans
    40. Wang H, Zhao S, Finnell RH, George T, Cooney AJ. Generation of integration-free induced pluripotent stem cells from a patient with spina bifida. Stem Cell Res. 2018 08; 31:27-30. PMID: 30007220.
      Citations: 1     Fields:    Translation:HumansCells
    41. Dong Y, Wang L, Lei Y, Yang N, Cabrera RM, Finnell RH, Ren A. Gene variants in the folate pathway are associated with increased levels of folate receptor autoantibodies. Birth Defects Res. 2018 07 17; 110(12):973-981. PMID: 29732742.
      Citations: 2     Fields:    Translation:Humans
    42. Gao X, Finnell RH, Wang H, Zheng Y. Network correlation analysis revealed potential new mechanisms for neural tube defects beyond folic acid. Birth Defects Res. 2018 07 17; 110(12):982-993. PMID: 29732722.
      Citations:    Fields:    Translation:Humans
    43. Kim J, Lei Y, Guo J, Kim SE, Wlodarczyk BJ, Cabrera RM, Lin YL, Nilsson TK, Zhang T, Ren A, Wang L, Yuan Z, Zheng YF, Wang HY, Finnell RH. Formate rescues neural tube defects caused by mutations in Slc25a32. Proc Natl Acad Sci U S A. 2018 05 01; 115(18):4690-4695. PMID: 29666258.
      Citations: 7     Fields:    Translation:HumansAnimals
    44. Chen Z, Lei Y, Cao X, Zheng Y, Wang F, Bao Y, Peng R, Finnell RH, Zhang T, Wang H. Genetic analysis of Wnt/PCP genes in neural tube defects. BMC Med Genomics. 2018 04 04; 11(1):38. PMID: 29618362.
      Citations: 5     Fields:    Translation:HumansCells
    45. Tian T, Wang L, Shen Y, Zhang B, Finnell RH, Ren A. Hypomethylation of GRHL3 gene is associated with the occurrence of neural tube defects. Epigenomics. 2018 07; 10(7):891-901. PMID: 29587534.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    46. Wang L, Xiao Y, Tian T, Jin L, Lei Y, Finnell RH, Ren A. Digenic variants of planar cell polarity genes in human neural tube defect patients. Mol Genet Metab. 2018 05; 124(1):94-100. PMID: 29573971.
      Citations: 4     Fields:    Translation:Humans
    47. Chen Z, Kuang L, Finnell RH, Wang H. Genetic and functional analysis of SHROOM1-4 in a Chinese neural tube defect cohort. Hum Genet. 2018 Mar; 137(3):195-202. PMID: 29423651.
      Citations: 2     Fields:    Translation:Humans
    48. Niedzwiecki MM, Liu X, Zhu H, Hall MN, Slavkovich V, Ilievski V, Levy D, Siddique AB, Kibriya MG, Parvez F, Islam T, Ahmed A, Navas-Acien A, Graziano JH, Finnell RH, Ahsan H, Gamble MV. Serum homocysteine, arsenic methylation, and arsenic-induced skin lesion incidence in Bangladesh: A one-carbon metabolism candidate gene study. Environ Int. 2018 04; 113:133-142. PMID: 29421402.
      Citations: 2     Fields:    Translation:HumansCells
    49. Waller DK, Hashmi SS, Hoyt AT, Duong HT, Tinker SC, Gallaway MS, Olney RS, Finnell RH, Hecht JT, Canfield MA. Maternal report of fever from cold or flu during early pregnancy and the risk for noncardiac birth defects, National Birth Defects Prevention Study, 1997-2011. Birth Defects Res. 2018 03 01; 110(4):342-351. PMID: 29094488.
      Citations: 3     Fields:    Translation:Humans
    50. Alam C, Hoque MT, Finnell RH, Goldman ID, Bendayan R. Regulation of Reduced Folate Carrier (RFC) by Vitamin D Receptor at the Blood-Brain Barrier. Mol Pharm. 2017 11 06; 14(11):3848-3858. PMID: 28885847.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    51. Vichier-Guerre C, Parker M, Pomerantz Y, Finnell RH, Cabrera RM. Impact of selective serotonin reuptake inhibitors on neural crest stem cell formation. Toxicol Lett. 2017 Nov 05; 281:20-25. PMID: 28844482.
      Citations: 2     Fields:    Translation:HumansCells
    52. Li P, Huang L, Zheng Y, Pan X, Peng R, Jiang Y, Finnell RH, Li H, Qiao B, Wang HY. A missense mutation in TCN2 is associated with decreased risk for congenital heart defects and may increase cellular uptake of vitamin B12 via Megalin. Oncotarget. 2017 Aug 15; 8(33):55216-55229. PMID: 28903415.
      Citations:    Fields:    
    53. Toriyama M, Toriyama M, Wallingford JB, Finnell RH. Folate-dependent methylation of septins governs ciliogenesis during neural tube closure. FASEB J. 2017 08; 31(8):3622-3635. PMID: 28432198.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    54. Lu HC, Tan Q, Rousseaux MW, Wang W, Kim JY, Richman R, Wan YW, Yeh SY, Patel JM, Liu X, Lin T, Lee Y, Fryer JD, Han J, Chahrour M, Finnell RH, Lei Y, Zurita-Jimenez ME, Ahimaz P, Anyane-Yeboa K, Van Maldergem L, Lehalle D, Jean-Marcais N, Mosca-Boidron AL, Thevenon J, Cousin MA, Bro DE, Lanpher BC, Klee EW, Alexander N, Bainbridge MN, Orr HT, Sillitoe RV, Ljungberg MC, Liu Z, Schaaf CP, Zoghbi HY. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 Apr; 49(4):527-536. PMID: 28288114.
      Citations: 18     Fields:    Translation:HumansAnimals
    55. Bibi D, Mawasi H, Nocentini A, Supuran CT, Wlodarczyk B, Finnell RH, Bialer M. Design and Comparative Evaluation of the Anticonvulsant Profile, Carbonic-Anhydrate Inhibition and Teratogenicity of Novel Carbamate Derivatives of Branched Aliphatic Carboxylic Acids with 4-Aminobenzensulfonamide. Neurochem Res. 2017 Jul; 42(7):1972-1982. PMID: 28275953.
      Citations:    Fields:    Translation:Animals
    56. Chen X, An Y, Gao Y, Guo L, Rui L, Xie H, Sun M, Lam Hung S, Sheng X, Zou J, Bao Y, Guan H, Niu B, Li Z, Finnell RH, Gusella JF, Wu BL, Zhang T. Rare Deleterious PARD3 Variants in the aPKC-Binding Region are Implicated in the Pathogenesis of Human Cranial Neural Tube Defects Via Disrupting Apical Tight Junction Formation. Hum Mutat. 2017 04; 38(4):378-389. PMID: 27925688.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    57. Akimova D, Wlodarczyk BJ, Lin Y, Ross ME, Finnell RH, Chen Q, Gross SS. Metabolite profiling of whole murine embryos reveals metabolic perturbations associated with maternal valproate-induced neural tube closure defects. Birth Defects Res. 2017 01 30; 109(2):106-119. PMID: 27860192.
      Citations: 3     Fields:    Translation:Animals
    58. Ross ME, Mason CE, Finnell RH. Genomic approaches to the assessment of human spina bifida risk. Birth Defects Res. 2017 01 30; 109(2):120-128. PMID: 27883265.
      Citations: 3     Fields:    Translation:Humans
    59. Bayer CL, Wlodarczyk BJ, Finnell RH, Emelianov SY. Ultrasound-guided spectral photoacoustic imaging of hemoglobin oxygenation during development. Biomed Opt Express. 2017 Feb 01; 8(2):757-763. PMID: 28270982.
      Citations:    
    60. Yang N, Wang L, Finnell RH, Li Z, Jin L, Zhang L, Cabrera RM, Ye R, Ren A. Corrigendum for: Levels of folate receptor autoantibodies in maternal and cord blood and risk of neural tube defects in a Chinese population, 106:685-695 (10.1002/bdra.23517). Birth Defects Res A Clin Mol Teratol. 2016 12; 106(12):1062. PMID: 28000437.
      Citations:    Fields:    
    61. McCollum CW, Conde-Vancells J, Hans C, Vazquez-Chantada M, Kleinstreuer N, Tal T, Knudsen T, Shah SS, Merchant FA, Finnell RH, Gustafsson JÅ, Cabrera R, Bondesson M. Identification of vascular disruptor compounds by analysis in zebrafish embryos and mouse embryonic endothelial cells. Reprod Toxicol. 2017 06; 70:60-69. PMID: 27838387.
      Citations: 2     Fields:    Translation:AnimalsCells
    62. Qiao X, Liu Y, Li P, Chen Z, Li H, Yang X, Finnell RH, Yang Z, Zhang T, Qiao B, Zheng Y, Wang H. Genetic analysis of rare coding mutations of CELSR1-3 in congenital heart and neural tube defects in Chinese people. Clin Sci (Lond). 2016 Dec 01; 130(24):2329-2340. PMID: 27756857.
      Citations: 8     Fields:    
    63. Brzóska HL, d'Esposito AM, Kolatsi-Joannou M, Patel V, Igarashi P, Lei Y, Finnell RH, Lythgoe MF, Woolf AS, Papakrivopoulou E, Long DA. Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning. Kidney Int. 2016 12; 90(6):1274-1284. PMID: 27597235.
      Citations: 10     Fields:    Translation:HumansAnimals
    64. Finnell RH, Shaw GM. Remembering Edward J. Lammer, MD. . 2016 Nov; 170(11):2767-2768. PMID: 27481654.
      Citations:    
    65. Yang N, Wang L, Finnell RH, Li Z, Jin L, Zhang L, Cabrera RM, Ye R, Ren A. Levels of folate receptor autoantibodies in maternal and cord blood and risk of neural tube defects in a Chinese population. Birth Defects Res A Clin Mol Teratol. 2016 Aug; 106(8):685-95. PMID: 27166990.
      Citations: 3     Fields:    Translation:Humans
    66. Denny KJ, Kelly CF, Kumar V, Witham KL, Cabrera RM, Finnell RH, Taylor SM, Jeanes A, Woodruff TM. Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects. Birth Defects Res A Clin Mol Teratol. 2016 Mar; 106(3):201-7. PMID: 26900104.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    67. Lei Y, Finnell RH. New Techniques for the Study of Neural Tube Defects. Adv Tech Biol Med. 2016 Feb; 4(1). PMID: 27066597.
      Citations:    
    68. Hill DS, Cabrera R, Wallis Schultz D, Zhu H, Lu W, Finnell RH, Wlodarczyk BJ. Autism-Like Behavior and Epigenetic Changes Associated with Autism as Consequences of In Utero Exposure to Environmental Pollutants in a Mouse Model. Behav Neurol. 2015; 2015:426263. PMID: 26586927.
      Citations: 11     Fields:    Translation:Animals
    69. Wlodarczyk BJ, Ogle K, Lin LY, Bialer M, Finnell RH. Comparative teratogenicity analysis of valnoctamide, risperidone, and olanzapine in mice. Bipolar Disord. 2015 Sep; 17(6):615-25. PMID: 26292082.
      Citations: 5     Fields:    Translation:Animals
    70. Shawlot W, Vazquez-Chantada M, Wallingford JB, Finnell RH. Rfx2 is required for spermatogenesis in the mouse. Genesis. 2015 Sep; 53(9):604-611. PMID: 26248850.
      Citations: 1     Fields:    
    71. Wang B, Jin L, Ren A, Yuan Y, Liu J, Li Z, Zhang L, Yi D, Wang LL, Zhang Y, Wang X, Tao S, Finnell RH. Correction to Levels of Polycyclic Aromatic Hydrocarbons in Maternal Serum and Risk of Neural Tube Defects in Offspring. Environ Sci Technol. 2015 Sep 01; 49(17):10754-5. PMID: 26274604.
      Citations:    Fields:    
    72. Cantarel BL, Lei Y, Weaver D, Zhu H, Farrell A, Benstead-Hume G, Reese J, Finnell RH. Analysis of archived residual newborn screening blood spots after whole genome amplification. BMC Genomics. 2015 Aug 13; 16:602. PMID: 26268606.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    73. Webber DM, MacLeod SL, Bamshad MJ, Shaw GM, Finnell RH, Shete SS, Witte JS, Erickson SW, Murphy LD, Hobbs C. Developments in our understanding of the genetic basis of birth defects. Birth Defects Res A Clin Mol Teratol. 2015 Aug; 103(8):680-91. PMID: 26033863.
      Citations: 7     Fields:    Translation:Humans
    74. Mawasi H, Shekh-Ahmad T, Finnell RH, Wlodarczyk BJ, Bialer M. Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid. Epilepsy Behav. 2015 May; 46:72-8. PMID: 25863940.
      Citations: 2     Fields:    Translation:AnimalsCells
    75. Lei Y, Fathe K, McCartney D, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH. Rare LRP6 variants identified in spina bifida patients. Hum Mutat. 2015 Mar; 36(3):342-9. PMID: 25546815.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    76. Wang B, Jin L, Ren A, Yuan Y, Liu J, Li Z, Zhang L, Yi D, Wang LL, Zhang Y, Wang X, Tao S, Finnell RH. Levels of polycyclic aromatic hydrocarbons in maternal serum and risk of neural tube defects in offspring. Environ Sci Technol. 2015 Jan 06; 49(1):588-96. PMID: 25488567.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    77. Yi D, Yuan Y, Jin L, Zhou G, Zhu H, Finnell RH, Ren A. Levels of PAH-DNA adducts in cord blood and cord tissue and the risk of fetal neural tube defects in a Chinese population. Neurotoxicology. 2015 Jan; 46:73-8. PMID: 25522656.
      Citations: 5     Fields:    Translation:Humans
    78. Shekh-Ahmad T, Mawasi H, McDonough JH, Finnell RH, Wlodarczyk BJ, Yavin E, Bialer M. Enantioselective pharmacodynamic and pharmacokinetic analysis of two chiral CNS-active carbamate derivatives of valproic acid. Epilepsia. 2014 Dec; 55(12):1944-52. PMID: 25442425.
      Citations: 1     Fields:    Translation:Animals
    79. Fathe K, Person MD, Finnell RH. The application of a chemical determination of N-homocysteinylation levels in developing mouse embryos: implication for folate responsive birth defects. J Nutr Biochem. 2015 Apr; 26(4):312-8. PMID: 25620692.
      Citations: 1     Fields:    Translation:Animals
    80. Martínez-Uña M, Varela-Rey M, Mestre D, Fernández-Ares L, Fresnedo O, Fernandez-Ramos D, Gutiérrez-de Juan V, Martin-Guerrero I, García-Orad A, Luka Z, Wagner C, Lu SC, García-Monzón C, Finnell RH, Aurrekoetxea I, Buqué X, Martínez-Chantar ML, Mato JM, Aspichueta P. S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease. J Hepatol. 2015 Mar; 62(3):673-81. PMID: 25457203.
      Citations: 18     Fields:    Translation:HumansAnimals
    81. Hansler A, Chen Q, Gray JD, Ross ME, Finnell RH, Gross SS. Untargeted metabolite profiling of murine embryos to reveal metabolic perturbations associated with neural tube closure defects. Birth Defects Res A Clin Mol Teratol. 2014 Aug; 100(8):623-32. PMID: 25115437.
      Citations: 5     Fields:    Translation:AnimalsCells
    82. Mitchell LE, Finnell RH. Papers from the Eighth International Neural Tube Defects Conference. Birth Defects Res A Clin Mol Teratol. 2014 Aug; 100(8):561-2. PMID: 25155952.
      Citations:    Fields:    Translation:HumansAnimals
    83. Fathe K, Palacios A, Finnell RH. Brief report novel mechanism for valproate-induced teratogenicity. Birth Defects Res A Clin Mol Teratol. 2014 Aug; 100(8):592-7. PMID: 25066307.
      Citations: 6     Fields:    Translation:HumansCells
    84. Tsurubuchi T, Allender EV, Siddiqui MR, Shim KW, Ichi S, Boshnjaku V, Mania-Farnell B, Xi G, Finnell RH, McLone DG, Tomita T, Mayanil CS. A critical role of noggin in developing folate-nonresponsive NTD in Fkbp8 -/- embryos. Childs Nerv Syst. 2014 Aug; 30(8):1343-53. PMID: 24817375.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    85. Lei Y, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH. Identification of novel CELSR1 mutations in spina bifida. PLoS One. 2014; 9(3):e92207. PMID: 24632739.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    86. Wlodarczyk BJ, Zhu H, Finnell RH. Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity. Toxicol Appl Pharmacol. 2014 Feb 15; 275(1):22-7. PMID: 24384392.
      Citations: 5     Fields:    Translation:AnimalsPHPublic Health
    87. Shekh-Ahmad T, Hen N, Yagen B, McDonough JH, Finnell RH, Wlodarczyk BJ, Bialer M. Stereoselective anticonvulsant and pharmacokinetic analysis of valnoctamide, a CNS-active derivative of valproic acid with low teratogenic potential. Epilepsia. 2014 Feb; 55(2):353-61. PMID: 24313671.
      Citations: 7     Fields:    Translation:Animals
    88. Lupo PJ, Mitchell LE, Canfield MA, Shaw GM, Olshan AF, Finnell RH, Zhu H. Maternal-fetal metabolic gene-gene interactions and risk of neural tube defects. Mol Genet Metab. 2014 Jan; 111(1):46-51. PMID: 24332798.
      Citations: 13     Fields:    Translation:Humans
    89. Denny KJ, Jeanes A, Fathe K, Finnell RH, Taylor SM, Woodruff TM. Neural tube defects, folate, and immune modulation. Birth Defects Res A Clin Mol Teratol. 2013 Sep; 97(9):602-609. PMID: 24078477.
      Citations: 8     Fields:    Translation:Humans
    90. Martínez-Uña M, Varela-Rey M, Cano A, Fernández-Ares L, Beraza N, Aurrekoetxea I, Martínez-Arranz I, García-Rodríguez JL, Buqué X, Mestre D, Luka Z, Wagner C, Alonso C, Finnell RH, Lu SC, Martínez-Chantar ML, Aspichueta P, Mato JM. Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis. Hepatology. 2013 Oct; 58(4):1296-305. PMID: 23505042.
      Citations: 29     Fields:    Translation:Animals
    91. Hen N, Shekh-Ahmad T, Yagen B, McDonough JH, Finnell RH, Wlodarczyk B, Bialer M. Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus. J Med Chem. 2013 Aug 22; 56(16):6467-77. PMID: 23879329.
      Citations: 3     Fields:    Translation:Animals
    92. Agopian AJ, Bhalla AD, Boerwinkle E, Finnell RH, Grove ML, Hixson JE, Shimmin LC, Sewda A, Stuart C, Zhong Y, Zhu H, Mitchell LE. Exon sequencing of PAX3 and T (brachyury) in cases with spina bifida. Birth Defects Res A Clin Mol Teratol. 2013 Sep; 97(9):597-601. PMID: 23913553.
      Citations: 2     Fields:    Translation:HumansCells
    93. Lei Y, Zhu H, Duhon C, Yang W, Ross ME, Shaw GM, Finnell RH. Mutations in planar cell polarity gene SCRIB are associated with spina bifida. PLoS One. 2013; 8(7):e69262. PMID: 23922697.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    94. Tabler JM, Barrell WB, Szabo-Rogers HL, Healy C, Yeung Y, Perdiguero EG, Schulz C, Yannakoudakis BZ, Mesbahi A, Wlodarczyk B, Geissmann F, Finnell RH, Wallingford JB, Liu KJ. Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes. Dev Cell. 2013 Jun 24; 25(6):623-35. PMID: 23806618.
      Citations: 25     Fields:    Translation:Animals
    95. Wallingford JB, Niswander LA, Shaw GM, Finnell RH. The continuing challenge of understanding, preventing, and treating neural tube defects. Science. 2013 Mar 01; 339(6123):1222002. PMID: 23449594.
      Citations: 118     Fields:    Translation:HumansAnimalsPHPublic Health
    96. Lai SC, Nakayama Y, Sequeira JM, Wlodarczyk BJ, Cabrera RM, Finnell RH, Bottiglieri T, Quadros EV. The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system. FASEB J. 2013 Jun; 27(6):2468-75. PMID: 23430977.
      Citations: 8     Fields:    Translation:HumansAnimals
    97. Denny KJ, Coulthard LG, Jeanes A, Lisgo S, Simmons DG, Callaway LK, Wlodarczyk B, Finnell RH, Woodruff TM, Taylor SM. C5a receptor signaling prevents folate deficiency-induced neural tube defects in mice. J Immunol. 2013 Apr 01; 190(7):3493-9. PMID: 23420882.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    98. Yuan Y, Jin L, Wang L, Li Z, Zhang L, Zhu H, Finnell RH, Zhou G, Ren A. Levels of PAH-DNA adducts in placental tissue and the risk of fetal neural tube defects in a Chinese population. Reprod Toxicol. 2013 Jun; 37:70-5. PMID: 23416326.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    99. Farkas SA, Böttiger AK, Isaksson HS, Finnell RH, Ren A, Nilsson TK. Epigenetic alterations in folate transport genes in placental tissue from fetuses with neural tube defects and in leukocytes from subjects with hyperhomocysteinemia. Epigenetics. 2013 Mar; 8(3):303-16. PMID: 23417011.
      Citations: 11     Fields:    Translation:HumansCells
    100. Denny KJ, Coulthard LG, Finnell RH, Callaway LK, Taylor SM, Woodruff TM. Elevated complement factor C5a in maternal and umbilical cord plasma in preeclampsia. J Reprod Immunol. 2013 Apr; 97(2):211-6. PMID: 23415845.
      Citations: 13     Fields:    Translation:Humans
    101. Wang X, Cabrera RM, Li Y, Miller DS, Finnell RH. Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice. FASEB J. 2013 Mar; 27(3):1167-75. PMID: 23212123.
      Citations: 8     Fields:    Translation:AnimalsCells
    102. Lupo PJ, Canfield MA, Chapa C, Lu W, Agopian AJ, Mitchell LE, Shaw GM, Waller DK, Olshan AF, Finnell RH, Zhu H. Diabetes and obesity-related genes and the risk of neural tube defects in the national birth defects prevention study. Am J Epidemiol. 2012 Dec 15; 176(12):1101-9. PMID: 23132673.
      Citations: 19     Fields:    Translation:Humans
    103. Wlodarczyk B, Spiegelstein O, Hill D, Le XC, Finnell RH. Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate. Toxicol Lett. 2012 Dec 17; 215(3):214-8. PMID: 23123153.
      Citations: 1     Fields:    Translation:Animals
    104. Cabrera RM, Finnell RH, Zhu H, Shaw GM, Wlodarczyk BJ. Transcriptional analyses of two mouse models of spina bifida. Birth Defects Res A Clin Mol Teratol. 2012 Oct; 94(10):782-9. PMID: 23024056.
      Citations:    Fields:    Translation:HumansAnimalsCells
    105. Lupo PJ, Chapa C, Nousome D, Duhon C, Canfield MA, Shaw GM, Finnell RH, Zhu H. A GCH1 haplotype and risk of neural tube defects in the National Birth Defects Prevention Study. Mol Genet Metab. 2012 Nov; 107(3):592-5. PMID: 23059057.
      Citations: 3     Fields:    Translation:Humans
    106. Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, Eppig JT, Finnell RH, Fletcher C, Fray M, Frendewey D, Friedel RH, Grosveld FG, Hansen J, Hérault Y, Hicks G, Hörlein A, Houghton R, Hrabé de Angelis M, Huylebroeck D, Iyer V, de Jong PJ, Kadin JA, Kaloff C, Kennedy K, Koutsourakis M, Lloyd KC, Marschall S, Mason J, McKerlie C, McLeod MP, von Melchner H, Moore M, Mujica AO, Nagy A, Nefedov M, Nutter LM, Pavlovic G, Peterson JL, Pollock J, Ramirez-Solis R, Rancourt DE, Raspa M, Remacle JE, Ringwald M, Rosen B, Rosenthal N, Rossant J, Ruiz Noppinger P, Ryder E, Schick JZ, Schnütgen F, Schofield P, Seisenberger C, Selloum M, Simpson EM, Skarnes WC, Smedley D, Stanford WL, Stewart AF, Stone K, Swan K, Tadepally H, Teboul L, Tocchini-Valentini GP, Valenzuela D, West AP, Yamamura K, Yoshinaga Y, Wurst W. The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome. 2012 Oct; 23(9-10):580-6. PMID: 22968824.
      Citations: 117     Fields:    Translation:Animals
    107. Etheredge AJ, Finnell RH, Carmichael SL, Lammer EJ, Zhu H, Mitchell LE, Shaw GM. Maternal and infant gene-folate interactions and the risk of neural tube defects. . 2012 Oct; 158A(10):2439-46. PMID: 22903727.
      Citations:    
    108. Zhu H, Yang W, Shaw N, Perloff S, Carmichael SL, Finnell RH, Shaw GM, Lammer EJ. Thymidylate synthase polymorphisms and risk of conotruncal heart defects. . 2012 Sep; 158A(9):2194-203. PMID: 22887475.
      Citations:    
    109. Wlodarczyk BJ, Palacios AM, George TM, Finnell RH. Antiepileptic drugs and pregnancy outcomes. . 2012 Aug; 158A(8):2071-90. PMID: 22711424.
      Citations:    
    110. Wallis D, Hill DS, Mendez IA, Abbott LC, Finnell RH, Wellman PJ, Setlow B. Initial characterization of mice null for Lphn3, a gene implicated in ADHD and addiction. Brain Res. 2012 Jun 29; 1463:85-92. PMID: 22575564.
      Citations: 20     Fields:    Translation:AnimalsCells
    111. Zhu H, Yang W, Lu W, Etheredge AJ, Lammer EJ, Finnell RH, Carmichael SL, Shaw GM. Gene variants in the folate-mediated one-carbon metabolism (FOCM) pathway as risk factors for conotruncal heart defects. . 2012 May; 158A(5):1124-34. PMID: 22495907.
      Citations:    
    112. Paschaki M, Lin SC, Wong RL, Finnell RH, Dollé P, Niederreither K. Retinoic acid-dependent signaling pathways and lineage events in the developing mouse spinal cord. PLoS One. 2012; 7(3):e32447. PMID: 22396766.
      Citations: 8     Fields:    Translation:AnimalsCells
    113. Lupo PJ, Langlois PH, Reefhuis J, Lawson CC, Symanski E, Desrosiers TA, Khodr ZG, Agopian AJ, Waters MA, Duwe KN, Finnell RH, Mitchell LE, Moore CA, Romitti PA, Shaw GM. Maternal occupational exposure to polycyclic aromatic hydrocarbons: effects on gastroschisis among offspring in the National Birth Defects Prevention Study. Environ Health Perspect. 2012 Jun; 120(6):910-5. PMID: 22330681.
      Citations: 22     Fields:    Translation:HumansPHPublic Health
    114. Psychoyos D, Vinod KY, Cao J, Xie S, Hyson RL, Wlodarczyk B, He W, Cooper TB, Hungund BL, Finnell RH. Cannabinoid receptor 1 signaling in embryo neurodevelopment. Birth Defects Res B Dev Reprod Toxicol. 2012 Apr; 95(2):137-50. PMID: 22311661.
      Citations: 12     Fields:    Translation:AnimalsCells
    115. Pessah N, Yagen B, Hen N, Shimshoni JA, Wlodarczyk B, Finnell RH, Bialer M. Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid. Epilepsy Behav. 2011 Nov; 22(3):461-8. PMID: 21959082.
      Citations: 1     Fields:    Translation:AnimalsCells
    116. Zhang Z, Wlodarczyk BJ, Niederreither K, Venugopalan S, Florez S, Finnell RH, Amendt BA. Fuz regulates craniofacial development through tissue specific responses to signaling factors. PLoS One. 2011; 6(9):e24608. PMID: 21935430.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    117. Ren A, Qiu X, Jin L, Ma J, Li Z, Zhang L, Zhu H, Finnell RH, Zhu T. Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects. Proc Natl Acad Sci U S A. 2011 Aug 02; 108(31):12770-5. PMID: 21768370.
      Citations: 46     Fields:    Translation:HumansPHPublic Health
    118. Wlodarczyk BJ, Palacios AM, Chapa CJ, Zhu H, George TM, Finnell RH. Genetic basis of susceptibility to teratogen induced birth defects. Am J Med Genet C Semin Med Genet. 2011 Aug 15; 157C(3):215-26. PMID: 21766441.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    119. Boyles AL, Ballard JL, Gorman EB, McConnaughey DR, Cabrera RM, Wilcox AJ, Lie RT, Finnell RH. Association between inhibited binding of folic acid to folate receptor alpha in maternal serum and folate-related birth defects in Norway. Hum Reprod. 2011 Aug; 26(8):2232-8. PMID: 21576080.
      Citations: 11     Fields:    Translation:Humans
    120. Wang J, Chen L, Wen S, Zhu H, Yu W, Moskowitz IP, Shaw GM, Finnell RH, Schwartz RJ. Defective sumoylation pathway directs congenital heart disease. Birth Defects Res A Clin Mol Teratol. 2011 Jun; 91(6):468-76. PMID: 21563299.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    121. Salojin KV, Cabrera RM, Sun W, Chang WC, Lin C, Duncan L, Platt KA, Read R, Vogel P, Liu Q, Finnell RH, Oravecz T. A mouse model of hereditary folate malabsorption: deletion of the PCFT gene leads to systemic folate deficiency. Blood. 2011 May 05; 117(18):4895-904. PMID: 21346251.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    122. Blanton SH, Henry RR, Yuan Q, Mulliken JB, Stal S, Finnell RH, Hecht JT. Folate pathway and nonsyndromic cleft lip and palate. Birth Defects Res A Clin Mol Teratol. 2011 Jan; 91(1):50-60. PMID: 21254359.
      Citations: 22     Fields:    Translation:Humans
    123. Dai D, Zhu H, Wlodarczyk B, Zhang L, Li L, Li AG, Finnell RH, Roop DR, Chen J. Fuz controls the morphogenesis and differentiation of hair follicles through the formation of primary cilia. J Invest Dermatol. 2011 Feb; 131(2):302-10. PMID: 20962855.
      Citations: 22     Fields:    Translation:AnimalsCells
    124. Lu W, Guzman AR, Yang W, Chapa CJ, Shaw GM, Greene RM, Pisano MM, Lammer EJ, Finnell RH, Zhu H. Genes encoding critical transcriptional activators for murine neural tube development and human spina bifida: a case-control study. BMC Med Genet. 2010 Oct 08; 11:141. PMID: 20932315.
      Citations: 6     Fields:    Translation:HumansAnimals
    125. Pessah N, Kaufmann D, Yagen B, Hen N, Wlodarczyk B, Finnell RH, Bialer M. Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid. Epilepsia. 2010 Oct; 51(10):1944-53. PMID: 20738383.
      Citations: 2     Fields:    Translation:HumansAnimals
    126. Obican SG, Finnell RH, Mills JL, Shaw GM, Scialli AR. Folic acid in early pregnancy: a public health success story. FASEB J. 2010 Nov; 24(11):4167-74. PMID: 20631328.
      Citations: 31     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    127. Hill DS, Wlodarczyk BJ, Palacios AM, Finnell RH. Teratogenic effects of antiepileptic drugs. Expert Rev Neurother. 2010 Jun; 10(6):943-59. PMID: 20518610.
      Citations: 21     Fields:    Translation:Humans
    128. Hen N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B. Syntheses and evaluation of anticonvulsant profile and teratogenicity of novel amide derivatives of branched aliphatic carboxylic acids with 4-aminobenzensulfonamide. J Med Chem. 2010 May 27; 53(10):4177-86. PMID: 20420384.
      Citations: 3     Fields:    Translation:Animals
    129. Iskandar BJ, Rizk E, Meier B, Hariharan N, Bottiglieri T, Finnell RH, Jarrard DF, Banerjee RV, Skene JH, Nelson A, Patel N, Gherasim C, Simon K, Cook TD, Hogan KJ. Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. J Clin Invest. 2010 May; 120(5):1603-16. PMID: 20424322.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    130. Finnell RH, Blom HJ, Shaw GM. Does global hypomethylation contribute to susceptibility to neural tube defects? Am J Clin Nutr. 2010 May; 91(5):1153-4. PMID: 20375188.
      Citations: 1     Fields:    Translation:HumansCells
    131. Rosenquist TH, Chaudoin T, Finnell RH, Bennett GD. High-affinity folate receptor in cardiac neural crest migration: a gene knockdown model using siRNA. Dev Dyn. 2010 Apr; 239(4):1136-44. PMID: 20235221.
      Citations: 3     Fields:    Translation:Animals
    132. Kaufmann D, Yagen B, Minert A, Wlodarczyk B, Finnell RH, Schurig V, Devor M, Bialer M. Evaluation of the antiallodynic, teratogenic and pharmacokinetic profile of stereoisomers of valnoctamide, an amide derivative of a chiral isomer of valproic acid. Neuropharmacology. 2010 Jun; 58(8):1228-36. PMID: 20230843.
      Citations: 6     Fields:    Translation:Animals
    133. Bille C, Pedersen DA, Andersen AM, Mansilla MA, Murray JC, Christensen K, Ballard JL, Gorman EB, Cabrera RM, Finnell RH. Autoantibodies to folate receptor alpha during early pregnancy and risk of oral clefts in Denmark. Pediatr Res. 2010 Mar; 67(3):274-9. PMID: 19952865.
      Citations: 7     Fields:    Translation:Humans
    134. Wen S, Zhu H, Lu W, Mitchell LE, Shaw GM, Lammer EJ, Finnell RH. Planar cell polarity pathway genes and risk for spina bifida. . 2010 Feb; 152A(2):299-304. PMID: 20101694.
      Citations:    
    135. Vázquez-Chantada M, Fernández-Ramos D, Embade N, Martínez-Lopez N, Varela-Rey M, Woodhoo A, Luka Z, Wagner C, Anglim PP, Finnell RH, Caballería J, Laird-Offringa IA, Gorospe M, Lu SC, Mato JM, Martínez-Chantar ML. HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis. Gastroenterology. 2010 May; 138(5):1943-53. PMID: 20102719.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    136. Pisano MM, Bhattacherjee V, Wong L, Finnell RH, Greene RM. Novel folate binding protein-1 interactions in embryonic orofacial tissue. Life Sci. 2010 Feb 13; 86(7-8):275-80. PMID: 20045418.
      Citations:    Fields:    Translation:AnimalsCells
    137. Shaw GM, Vollset SE, Carmichael SL, Yang W, Finnell RH, Blom H, Ueland PM. Nested case-control study of one-carbon metabolites in mid-pregnancy and risks of cleft lip with and without cleft palate. Pediatr Res. 2009 Nov; 66(5):501-6. PMID: 19668105.
      Citations: 6     Fields:    Translation:Humans
    138. Gray RS, Abitua PB, Wlodarczyk BJ, Szabo-Rogers HL, Blanchard O, Lee I, Weiss GS, Liu KJ, Marcotte EM, Wallingford JB, Finnell RH. The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol. 2009 Oct; 11(10):1225-32. PMID: 19767740.
      Citations: 90     Fields:    Translation:AnimalsCells
    139. Shaw GM, Finnell RH, Blom HJ, Carmichael SL, Vollset SE, Yang W, Ueland PM. Choline and risk of neural tube defects in a folate-fortified population. Epidemiology. 2009 Sep; 20(5):714-9. PMID: 19593156.
      Citations: 39     Fields:    Translation:Humans
    140. Shimshoni JA, Yagen B, Wlodarczyk B, Finnell RH, Schurig V, Bialer M. Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative. Epilepsia. 2010 Mar; 51(3):323-32. PMID: 19674061.
      Citations: 1     Fields:    Translation:Animals
    141. Hardin J, Finnell RH, Wong D, Hogan ME, Horovitz J, Shu J, Shaw GM. Whole genome microarray analysis, from neonatal blood cards. BMC Genet. 2009 Jul 22; 10:38. PMID: 19624846.
      Citations: 12     Fields:    Translation:Humans
    142. Kibar Z, Bosoi CM, Kooistra M, Salem S, Finnell RH, De Marco P, Merello E, Bassuk AG, Capra V, Gros P. Novel mutations in VANGL1 in neural tube defects. Hum Mutat. 2009 Jul; 30(7):E706-15. PMID: 19319979.
      Citations: 48     Fields:    Translation:Humans
    143. Shaw GM, Lu W, Zhu H, Yang W, Briggs FB, Carmichael SL, Barcellos LF, Lammer EJ, Finnell RH. 118 SNPs of folate-related genes and risks of spina bifida and conotruncal heart defects. BMC Med Genet. 2009 Jun 03; 10:49. PMID: 19493349.
      Citations: 67     Fields:    Translation:Humans
    144. Shi Z, Cai Z, Wen S, Chen C, Gendron C, Sanchez A, Patterson K, Fu S, Yang J, Wildman D, Finnell RH, Zhang D. Transcriptional regulation of the novel Toll-like receptor Tlr13. J Biol Chem. 2009 Jul 31; 284(31):20540-7. PMID: 19487701.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    145. Hill DS, Wlodarczyk BJ, Mitchell LE, Finnell RH. Arsenate-induced maternal glucose intolerance and neural tube defects in a mouse model. Toxicol Appl Pharmacol. 2009 Aug 15; 239(1):29-36. PMID: 19446573.
      Citations: 16     Fields:    Translation:AnimalsPHPublic Health
    146. Zhu H, Kartiko S, Finnell RH. Importance of gene-environment interactions in the etiology of selected birth defects. Clin Genet. 2009 May; 75(5):409-23. PMID: 19459879.
      Citations: 30     Fields:    Translation:HumansAnimalsPHPublic Health
    147. Harden CL, Meador KJ, Pennell PB, Hauser WA, Gronseth GS, French JA, Wiebe S, Thurman D, Koppel BS, Kaplan PW, Robinson JN, Hopp J, Ting TY, Gidal B, Hovinga CA, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Hirtz D, Le Guen C. Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes: Report of the Quality Standards Subcommittee and Therapeutics and Technology Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Epilepsia. 2009 May; 50(5):1237-46. PMID: 19507301.
      Citations: 47     Fields:    Translation:Humans
    148. Harden CL, Hopp J, Ting TY, Pennell PB, French JA, Allen Hauser W, Wiebe S, Gronseth GS, Thurman D, Meador KJ, Koppel BS, Kaplan PW, Robinson JN, Gidal B, Hovinga CA, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Le Guen C. Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): I. Obstetrical complications and change in seizure frequency: Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Epilepsia. 2009 May; 50(5):1229-36. PMID: 19496807.
      Citations: 18     Fields:    Translation:Humans
    149. Harden CL, Pennell PB, Koppel BS, Hovinga CA, Gidal B, Meador KJ, Hopp J, Ting TY, Hauser WA, Thurman D, Kaplan PW, Robinson JN, French JA, Wiebe S, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Shafer PO, Le Guen CL. Management issues for women with epilepsy--focus on pregnancy (an evidence-based review): III. Vitamin K, folic acid, blood levels, and breast-feeding: Report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the American Epilepsy Society. Epilepsia. 2009 May; 50(5):1247-55. PMID: 19507305.
      Citations: 27     Fields:    Translation:Humans
    150. Harden CL, Pennell PB, Koppel BS, Hovinga CA, Gidal B, Meador KJ, Hopp J, Ting TY, Hauser WA, Thurman D, Kaplan PW, Robinson JN, French JA, Wiebe S, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Shafer PO, Le Guen C. Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): vitamin K, folic acid, blood levels, and breastfeeding: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society. Neurology. 2009 Jul 14; 73(2):142-9. PMID: 19398680.
      Citations: 45     Fields:    Translation:Humans
    151. Harden CL, Meador KJ, Pennell PB, Hauser WA, Gronseth GS, French JA, Wiebe S, Thurman D, Koppel BS, Kaplan PW, Robinson JN, Hopp J, Ting TY, Gidal B, Hovinga CA, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Hirtz D, Le Guen C. Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): teratogenesis and perinatal outcomes: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society. Neurology. 2009 Jul 14; 73(2):133-41. PMID: 19398681.
      Citations: 56     Fields:    Translation:Humans
    152. Harden CL, Hopp J, Ting TY, Pennell PB, French JA, Hauser WA, Wiebe S, Gronseth GS, Thurman D, Meador KJ, Koppel BS, Kaplan PW, Robinson JN, Gidal B, Hovinga CA, Wilner AN, Vazquez B, Holmes L, Krumholz A, Finnell R, Le Guen C. Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): obstetrical complications and change in seizure frequency: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society. Neurology. 2009 Jul 14; 73(2):126-32. PMID: 19398682.
      Citations: 38     Fields:    Translation:Humans
    153. Pessah N, Bialer M, Wlodarczyk B, Finnell RH, Yagen B. Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid. J Med Chem. 2009 Apr 23; 52(8):2233-42. PMID: 19296679.
      Citations: 3     Fields:    Translation:Animals
    154. Salbaum JM, Finnell RH, Kappen C. Regulation of folate receptor 1 gene expression in the visceral endoderm. Birth Defects Res A Clin Mol Teratol. 2009 Apr; 85(4):303-13. PMID: 19180647.
      Citations: 6     Fields:    Translation:AnimalsCells
    155. Naufal Z, Zhiwen L, Zhu L, Zhou GD, McDonald T, He LY, Mitchell L, Ren A, Zhu H, Finnell R, Donnelly KC. Biomarkers of exposure to combustion by-products in a human population in Shanxi, China. J Expo Sci Environ Epidemiol. 2010 Jun; 20(4):310-9. PMID: 19277067.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    156. Psychoyos D, Finnell R. Assay for neural induction in the chick embryo. J Vis Exp. 2009 Feb 13; (24). PMID: 19229186.
      Citations: 1     Fields:    Translation:Animals
    157. Jakubowski H, Perla-Kaján J, Finnell RH, Cabrera RM, Wang H, Gupta S, Kruger WD, Kraus JP, Shih DM. Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice. FASEB J. 2009 Jun; 23(6):1721-7. PMID: 19204075.
      Citations: 28     Fields:    Translation:HumansAnimals
    158. Psychoyos D, Finnell R. Method for whole mount antibody staining in chick. J Vis Exp. 2009 Feb 02; (24). PMID: 19488030.
      Citations: 1     Fields:    Translation:Animals
    159. Wen S, Lu W, Zhu H, Yang W, Shaw GM, Lammer EJ, Islam A, Finnell RH. Genetic polymorphisms in the thioredoxin 2 (TXN2) gene and risk for spina bifida. . 2009 Feb; 149A(2):155-60. PMID: 19165900.
      Citations:    
    160. Shaw GM, Carmichael SL, Vollset SE, Yang W, Finnell RH, Blom H, Midttun Ø, Ueland PM. Mid-pregnancy cotinine and risks of orofacial clefts and neural tube defects. J Pediatr. 2009 Jan; 154(1):17-9. PMID: 18990410.
      Citations: 18     Fields:    Translation:Humans
    161. Psychoyos D, Finnell R. Double whole mount in situ hybridization of early chick embryos. J Vis Exp. 2008 Oct 27; (20). PMID: 19078944.
      Citations: 1     Fields:    Translation:Animals
    162. Psychoyos D, Finnell R. Method for Culture of Early Chick Embryos ex vivo (New Culture). J Vis Exp. 2008 Oct 20; (20). PMID: 19078945.
      Citations: 2     Fields:    Translation:Animals
    163. Chapkin RS, Kamen BA, Callaway ES, Davidson LA, George NI, Wang N, Lupton JR, Finnell RH. Use of a novel genetic mouse model to investigate the role of folate in colitis-associated colon cancer. J Nutr Biochem. 2009 Aug; 20(8):649-55. PMID: 18926688.
      Citations: 5     Fields:    Translation:Animals
    164. Psychoyos D, Hungund B, Cooper T, Finnell RH. A cannabinoid analogue of Delta9-tetrahydrocannabinol disrupts neural development in chick. Birth Defects Res B Dev Reprod Toxicol. 2008 Oct; 83(5):477-88. PMID: 19040278.
      Citations: 10     Fields:    Translation:Animals
    165. Lu W, Zhu H, Wen S, Yang W, Shaw GM, Lammer EJ, Finnell RH. Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida. Birth Defects Res A Clin Mol Teratol. 2008 Oct; 82(10):670-5. PMID: 18553462.
      Citations: 2     Fields:    Translation:Humans
    166. Cabrera RM, Shaw GM, Ballard JL, Carmichael SL, Yang W, Lammer EJ, Finnell RH. Autoantibodies to folate receptor during pregnancy and neural tube defect risk. J Reprod Immunol. 2008 Oct; 79(1):85-92. PMID: 18804286.
      Citations: 18     Fields:    Translation:Humans
    167. Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct; 18(10):1670-9. PMID: 18799693.
      Citations: 56     Fields:    Translation:AnimalsCells
    168. Chapin R, Augustine-Rauch K, Beyer B, Daston G, Finnell R, Flynn T, Hunter S, Mirkes P, O'Shea KS, Piersma A, Sandler D, Vanparys P, Van Maele-Fabry G. State of the art in developmental toxicity screening methods and a way forward: a meeting report addressing embryonic stem cells, whole embryo culture, and zebrafish. Birth Defects Res B Dev Reprod Toxicol. 2008 Aug; 83(4):446-56. PMID: 18702117.
      Citations: 5     Fields:    Translation:AnimalsCells
    169. Shimshoni JA, Yagen B, Pessah N, Wlodarczyk B, Finnell RH, Bialer M. Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid. Epilepsia. 2008 Jul; 49(7):1202-12. PMID: 18435754.
      Citations: 2     Fields:    Translation:Animals
    170. Gelineau-van Waes J, Heller S, Bauer LK, Wilberding J, Maddox JR, Aleman F, Rosenquist TH, Finnell RH. Embryonic development in the reduced folate carrier knockout mouse is modulated by maternal folate supplementation. Birth Defects Res A Clin Mol Teratol. 2008 Jul; 82(7):494-507. PMID: 18383508.
      Citations: 21     Fields:    Translation:Animals
    171. Finnell RH, Shaw GM, Lammer EJ, Rosenquist TH. Gene-nutrient interactions: importance of folic acid and vitamin B12 during early embryogenesis. Food Nutr Bull. 2008 Jun; 29(2 Suppl):S86-98; discussion S99-100. PMID: 18709884.
      Citations: 4     Fields:    Translation:Humans
    172. Gelineau-van Waes J, Maddox JR, Smith LM, van Waes M, Wilberding J, Eudy JD, Bauer LK, Finnell RH. Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. BMC Genomics. 2008 Apr 09; 9:156. PMID: 18400109.
      Citations: 9     Fields:    Translation:Animals
    173. Hill DS, Wlodarczyk BJ, Finnell RH. Reproductive consequences of oral arsenate exposure during pregnancy in a mouse model. Birth Defects Res B Dev Reprod Toxicol. 2008 Feb; 83(1):40-7. PMID: 18186108.
      Citations: 17     Fields:    Translation:AnimalsPHPublic Health
    174. Kappen C, Neubüser A, Balling R, Finnell R. Molecular basis for skeletal variation: insights from developmental genetic studies in mice. Birth Defects Res B Dev Reprod Toxicol. 2007 Dec; 80(6):425-50. PMID: 18157899.
      Citations: 2     Fields:    Translation:Animals
    175. Zhu H, Cabrera RM, Wlodarczyk BJ, Bozinov D, Wang D, Schwartz RJ, Finnell RH. Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity. BMC Dev Biol. 2007 Nov 20; 7:128. PMID: 18028541.
      Citations: 14     Fields:    Translation:Animals
    176. Wong RL, Wlodarczyk BJ, Min KS, Scott ML, Kartiko S, Yu W, Merriweather MY, Vogel P, Zambrowicz BP, Finnell RH. Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube. Hum Mol Genet. 2008 Feb 15; 17(4):587-601. PMID: 18003640.
      Citations: 16     Fields:    Translation:HumansAnimals
    177. Shimshoni JA, Bialer M, Wlodarczyk B, Finnell RH, Yagen B. Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. J Med Chem. 2007 Dec 13; 50(25):6419-27. PMID: 17994680.
      Citations: 4     Fields:    Translation:Animals
    178. Shaw GM, Carmichael SL, Laurent C, Louik C, Finnell RH, Lammer EJ. Nutrient intakes in women and risks of anophthalmia and microphthalmia in their offspring. Birth Defects Res A Clin Mol Teratol. 2007 Oct; 79(10):708-13. PMID: 17847120.
      Citations: 1     Fields:    Translation:Humans
    179. Ramirez D, Lammer EJ, Iovannisci DM, Laurent C, Finnell RH, Shaw GM. Maternal smoking during early pregnancy, GSTP1 and EPHX1 variants, and risk of isolated orofacial clefts. Cleft Palate Craniofac J. 2007 Jul; 44(4):366-73. PMID: 17608547.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    180. Collins FS, Finnell RH, Rossant J, Wurst W. A new partner for the international knockout mouse consortium. Cell. 2007 Apr 20; 129(2):235. PMID: 17448981.
      Citations: 43     Fields:    Translation:AnimalsCells
    181. Zhu H, Wlodarczyk BJ, Scott M, Yu W, Merriweather M, Gelineau-van Waes J, Schwartz RJ, Finnell RH. Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. Birth Defects Res A Clin Mol Teratol. 2007 Apr; 79(4):257-68. PMID: 17286298.
      Citations: 9     Fields:    Translation:Animals
    182. Rosenquist TH, Bennett GD, Brauer PR, Stewart ML, Chaudoin TR, Finnell RH. Microarray analysis of homocysteine-responsive genes in cardiac neural crest cells in vitro. Dev Dyn. 2007 Apr; 236(4):1044-54. PMID: 17326132.
      Citations: 5     Fields:    Translation:AnimalsCells
    183. Zhu H, Enaw JO, Ma C, Shaw GM, Lammer EJ, Finnell RH. Association between CFL1 gene polymorphisms and spina bifida risk in a California population. BMC Med Genet. 2007 Mar 12; 8:12. PMID: 17352815.
      Citations: 7     Fields:    Translation:Humans
    184. Chevrier C, Perret C, Bahuau M, Zhu H, Nelva A, Herman C, Francannet C, Robert-Gnansia E, Finnell RH, Cordier S. Fetal and maternal MTHFR C677T genotype, maternal folate intake and the risk of nonsyndromic oral clefts. . 2007 Feb 01; 143A(3):248-57. PMID: 17219389.
      Citations:    
    185. Lu W, Zhu H, Wen S, Laurent C, Shaw GM, Lammer EJ, Finnell RH. Screening for novel PAX3 polymorphisms and risks of spina bifida. Birth Defects Res A Clin Mol Teratol. 2007 Jan; 79(1):45-9. PMID: 17149730.
      Citations: 7     Fields:    Translation:Humans
    186. Shaw GM, Jelliffe-Pawlowski L, Nelson V, Zhu H, Harris JA, Finnell RH. Infant C677T MTHFR polymorphism and severe mental retardation. Birth Defects Res A Clin Mol Teratol. 2007 Jan; 79(1):24-6. PMID: 17149733.
      Citations:    Fields:    Translation:Humans
    187. Taparia S, Gelineau-van Waes J, Rosenquist TH, Finnell RH. Importance of folate-homocysteine homeostasis during early embryonic development. Clin Chem Lab Med. 2007; 45(12):1717-27. PMID: 18067451.
      Citations: 17     Fields:    Translation:Animals
    188. Enaw JO, Zhu H, Yang W, Lu W, Shaw GM, Lammer EJ, Finnell RH. CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population. BMC Med. 2006 Dec 21; 4:36. PMID: 17184542.
      Citations: 11     Fields:    Translation:Humans
    189. Carmichael SL, Shaw GM, Iovannisci DM, Yang W, Finnell RH, Cheng S, Lammer EJ. Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation. . 2006 Nov 15; 140(22):2433-40. PMID: 17036337.
      Citations:    
    190. Rosenquist TH, Finnell RH. Another key role for the cardiac neural crest in heart development. . 2007 Mar; 292(3):H1225-6. PMID: 17098821.
      Citations:    
    191. Sobol E, Yagen B, Lamb JG, White HS, Wlodarczyk BJ, Finnell RH, Bialer M. Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide. Epilepsy Res. 2007 Jan; 73(1):75-84. PMID: 16997532.
      Citations: 1     Fields:    Translation:Animals
    192. Lawrance AK, Deng L, Brody LC, Finnell RH, Shane B, Rozen R. Genetic and nutritional deficiencies in folate metabolism influence tumorigenicity in Apcmin/+ mice. J Nutr Biochem. 2007 May; 18(5):305-12. PMID: 16963246.
      Citations: 6     Fields:    Translation:AnimalsCells
    193. Blom HJ, Shaw GM, den Heijer M, Finnell RH. Neural tube defects and folate: case far from closed. Nat Rev Neurosci. 2006 Sep; 7(9):724-31. PMID: 16924261.
      Citations: 136     Fields:    Translation:HumansAnimalsCells
    194. Meador KJ, Baker GA, Finnell RH, Kalayjian LA, Liporace JD, Loring DW, Mawer G, Pennell PB, Smith JC, Wolff MC. In utero antiepileptic drug exposure: fetal death and malformations. Neurology. 2006 Aug 08; 67(3):407-12. PMID: 16894099.
      Citations: 60     Fields:    Translation:Humans
    195. Sobol E, Yagen B, Steve White H, Wilcox KS, Lamb JG, Pappo O, Wlodarczyk BJ, Finnell RH, Bialer M. Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug. Neuropharmacology. 2006 Sep; 51(4):933-46. PMID: 16890251.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    196. Wlodarczyk BJ, Cabrera RM, Hill DS, Bozinov D, Zhu H, Finnell RH. Arsenic-induced gene expression changes in the neural tube of folate transport defective mouse embryos. Neurotoxicology. 2006 Jul; 27(4):547-57. PMID: 16620997.
      Citations: 10     Fields:    Translation:Animals
    197. Zhang J, Zhu H, Yang W, Shaw GM, Lammer EJ, Finnell RH. Phosphatidylethanolamine N-methyltransferase (PEMT) gene polymorphisms and risk of spina bifida. . 2006 Apr 01; 140(7):785-9. PMID: 16523512.
      Citations:    
    198. Zhu J, Ren A, Hao L, Pei L, Liu J, Zhu H, Li S, Finnell RH, Li Z. Variable contribution of the MTHFR C677T polymorphism to non-syndromic cleft lip and palate risk in China. . 2006 Mar 15; 140(6):551-7. PMID: 16470725.
      Citations:    
    199. Massa V, Wlodarczyk B, Giavini E, Finnell RH. Myo-inositol enhances teratogenicity of valproic acid in the mouse. Birth Defects Res A Clin Mol Teratol. 2006 Mar; 76(3):200-4. PMID: 16511884.
      Citations: 2     Fields:    Translation:Animals
    200. Abdelrahim M, Ariazi E, Kim K, Khan S, Barhoumi R, Burghardt R, Liu S, Hill D, Finnell R, Wlodarczyk B, Jordan VC, Safe S. 3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer Res. 2006 Feb 15; 66(4):2459-67. PMID: 16489053.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    201. Shaw GM, Iovannisci DM, Yang W, Finnell RH, Carmichael SL, Cheng S, Lammer EJ. Endothelial nitric oxide synthase (NOS3) genetic variants, maternal smoking, vitamin use, and risk of human orofacial clefts. Am J Epidemiol. 2005 Dec 15; 162(12):1207-14. PMID: 16269583.
      Citations: 12     Fields:    Translation:HumansPHPublic Health
    202. Massa V, Cabrera RM, Menegola E, Giavini E, Finnell RH. Valproic acid-induced skeletal malformations: associated gene expression cascades. Pharmacogenet Genomics. 2005 Nov; 15(11):787-800. PMID: 16220111.
      Citations: 7     Fields:    Translation:HumansAnimals
    203. Zhu H, Yang W, Lu W, Zhang J, Shaw GM, Lammer EJ, Finnell RH. A known functional polymorphism (Ile120Val) of the human PCMT1 gene and risk of spina bifida. Mol Genet Metab. 2006 Jan; 87(1):66-70. PMID: 16256389.
      Citations: 8     Fields:    Translation:Humans
    204. Wlodarczyk BJ, Tang LS, Triplett A, Aleman F, Finnell RH. Spontaneous neural tube defects in splotch mice supplemented with selected micronutrients. Toxicol Appl Pharmacol. 2006 May 15; 213(1):55-63. PMID: 16226775.
      Citations: 23     Fields:    Translation:Animals
    205. Shaw GM, Iovannisci DM, Yang W, Finnell RH, Carmichael SL, Cheng S, Lammer EJ. Risks of human conotruncal heart defects associated with 32 single nucleotide polymorphisms of selected cardiovascular disease-related genes. . 2005 Sep 15; 138(1):21-6. PMID: 16100725.
      Citations:    
    206. Zhu H, Lu W, Laurent C, Shaw GM, Lammer EJ, Finnell RH. Genes encoding catalytic subunits of protein kinase A and risk of spina bifida. Birth Defects Res A Clin Mol Teratol. 2005 Sep; 73(9):591-6. PMID: 16080189.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    207. Blanton SH, Cortez A, Stal S, Mulliken JB, Finnell RH, Hecht JT. Variation in IRF6 contributes to nonsyndromic cleft lip and palate. . 2005 Sep 01; 137A(3):259-62. PMID: 16096995.
      Citations:    
    208. Lammer EJ, Shaw GM, Iovannisci DM, Finnell RH. Maternal smoking, genetic variation of glutathione s-transferases, and risk for orofacial clefts. Epidemiology. 2005 Sep; 16(5):698-701. PMID: 16135950.
      Citations: 23     Fields:    Translation:HumansPHPublic Health
    209. Shaw GM, Carmichael SL, Yang W, Harris JA, Finnell RH, Lammer EJ. Epidemiologic characteristics of anophthalmia and bilateral microphthalmia among 2.5 million births in California, 1989-1997. . 2005 Aug 15; 137(1):36-40. PMID: 16007635.
      Citations:    
    210. Lu W, Volcik K, Zhu H, Wen S, Shaw GM, Lammer EJ, Finnell RH. Genetic variation in the proto-oncogene SKI and risk for orofacial clefting. Mol Genet Metab. 2005 Nov; 86(3):412-6. PMID: 16054854.
      Citations: 1     Fields:    Translation:Humans
    211. Pei L, Zhu H, Zhu J, Ren A, Finnell RH, Li Z. Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial defects and congenital heart defects in China. Ann Epidemiol. 2006 May; 16(5):352-6. PMID: 16019224.
      Citations: 18     Fields:    Translation:Humans
    212. Zhu H, Curry S, Wen S, Wicker NJ, Shaw GM, Lammer EJ, Yang W, Jafarov T, Finnell RH. Are the betaine-homocysteine methyltransferase (BHMT and BHMT2) genes risk factors for spina bifida and orofacial clefts? . 2005 Jun 15; 135(3):274-7. PMID: 15887275.
      Citations:    
    213. Olshan AF, Shaw GM, Millikan RC, Laurent C, Finnell RH. Polymorphisms in DNA repair genes as risk factors for spina bifida and orofacial clefts. . 2005 Jun 15; 135(3):268-73. PMID: 15887293.
      Citations:    
    214. Pei L, Zhu H, Ren A, Li Z, Hao L, Finnell RH, Li Z. Reduced folate carrier gene is a risk factor for neural tube defects in a Chinese population. Birth Defects Res A Clin Mol Teratol. 2005 Jun; 73(6):430-3. PMID: 15799025.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    215. Tang LS, Santillano DR, Wlodarczyk BJ, Miranda RC, Finnell RH. Role of Folbp1 in the regional regulation of apoptosis and cell proliferation in the developing neural tube and craniofacies. Am J Med Genet C Semin Med Genet. 2005 May 15; 135C(1):48-58. PMID: 15800851.
      Citations: 8     Fields:    Translation:AnimalsCells
    216. Moretti P, Sahoo T, Hyland K, Bottiglieri T, Peters S, del Gaudio D, Roa B, Curry S, Zhu H, Finnell RH, Neul JL, Ramaekers VT, Blau N, Bacino CA, Miller G, Scaglia F. Cerebral folate deficiency with developmental delay, autism, and response to folinic acid. Neurology. 2005 Mar 22; 64(6):1088-90. PMID: 15781839.
      Citations: 35     Fields:    Translation:Humans
    217. Spiegelstein O, Gould A, Wlodarczyk B, Tsie M, Lu X, Le C, Troen A, Selhub J, Piedrahita JA, Salbaum JM, Kappen C, Melnyk S, James J, Finnell RH. Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies. Toxicol Appl Pharmacol. 2005 Feb 15; 203(1):18-26. PMID: 15694460.
      Citations: 10     Fields:    Translation:Animals
    218. Birn H, Spiegelstein O, Christensen EI, Finnell RH. Renal tubular reabsorption of folate mediated by folate binding protein 1. J Am Soc Nephrol. 2005 Mar; 16(3):608-15. PMID: 15703271.
      Citations: 25     Fields:    Translation:AnimalsCells
    219. Ma DW, Finnell RH, Davidson LA, Callaway ES, Spiegelstein O, Piedrahita JA, Salbaum JM, Kappen C, Weeks BR, James J, Bozinov D, Lupton JR, Chapkin RS. Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis. Cancer Res. 2005 Feb 01; 65(3):887-97. PMID: 15705887.
      Citations: 21     Fields:    Translation:Animals
    220. Jafarov T, Zhu H, Finnell R, Kulieva S. Epidemiologic study on HFE C282Y mutation in Azerbaijan. Eur J Haematol. 2005 Feb; 74(2):180-1. PMID: 15654913.
      Citations:    Fields:    Translation:Humans
    221. Rosenquist TH, van Waes JG, Shaw GM, Finnell R. Nutrient effects upon embryogenesis: folate, vitamin A and iodine. Nestle Nutr Workshop Ser Pediatr Program. 2005; 55:29-40; discussion 40-8. PMID: 16632927.
      Citations: 1     Fields:    Translation:Humans
    222. Spiegelstein O, Lu X, Le XC, Troen A, Selhub J, Melnyk S, James SJ, Finnell RH. Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice. Environ Toxicol Pharmacol. 2005 Jan; 19(1):1-7. PMID: 21783456.
      Citations: 5     Fields:    
    223. Cabrera RM, Hill DS, Etheredge AJ, Finnell RH. Investigations into the etiology of neural tube defects. Birth Defects Res C Embryo Today. 2004 Dec; 72(4):330-44. PMID: 15662706.
      Citations: 18     Fields:    Translation:Humans
    224. Lammer EJ, Shaw GM, Iovannisci DM, Finnell RH. Periconceptional multivitamin intake during early pregnancy, genetic variation of acetyl-N-transferase 1 (NAT1), and risk for orofacial clefts. Birth Defects Res A Clin Mol Teratol. 2004 Nov; 70(11):846-52. PMID: 15523664.
      Citations: 20     Fields:    Translation:Humans
    225. Spiegelstein O, Mitchell LE, Merriweather MY, Wicker NJ, Zhang Q, Lammer EJ, Finnell RH. Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation. Dev Dyn. 2004 Sep; 231(1):221-31. PMID: 15305303.
      Citations: 28     Fields:    Translation:Animals
    226. Finnell RH, Shaw GM, Lammer EJ, Brandl KL, Carmichael SL, Rosenquist TH. Gene-nutrient interactions: importance of folates and retinoids during early embryogenesis. Toxicol Appl Pharmacol. 2004 Jul 15; 198(2):75-85. PMID: 15236946.
      Citations: 12     Fields:    Translation:HumansAnimalsPHPublic Health
    227. Kappen C, Mello MA, Finnell RH, Salbaum JM. Folate modulates Hox gene-controlled skeletal phenotypes. Genesis. 2004 Jul; 39(3):155-66. PMID: 15282741.
      Citations: 8     Fields:    Translation:Animals
    228. Tang LS, Wlodarczyk BJ, Santillano DR, Miranda RC, Finnell RH. Developmental consequences of abnormal folate transport during murine heart morphogenesis. Birth Defects Res A Clin Mol Teratol. 2004 Jul; 70(7):449-58. PMID: 15259034.
      Citations: 10     Fields:    Translation:AnimalsCells
    229. Spiegelstein O, Cabrera RM, Bozinov D, Wlodarczyk B, Finnell RH. Folate-regulated changes in gene expression in the anterior neural tube of folate binding protein-1 (Folbp1)-deficient murine embryos. Neurochem Res. 2004 Jun; 29(6):1105-12. PMID: 15176467.
      Citations: 5     Fields:    Translation:AnimalsCells
    230. Lundberg YW, Cabrera RM, Greer KA, Zhao J, Garg R, Finnell RH. Mapping a chromosomal locus for valproic acid-induced exencephaly in mice. Mamm Genome. 2004 May; 15(5):361-9. PMID: 15170225.
      Citations: 2     Fields:    Translation:AnimalsPHPublic Health
    231. Volcik KA, Zhu H, Finnell RH, Shaw GM, Canfield M, Lammer EJ. Evaluation of the Cited2 gene and risk for spina bifida and congenital heart defects. . 2004 Apr 30; 126A(3):324-5. PMID: 15054851.
      Citations:    
    232. Volcik KA, Zhu H, Finnell RH, Shaw GM, Canfield M, Lammer EJ. Evaluation of the jumonji gene and risk for spina bifida and congenital heart defects. . 2004 Apr 15; 126A(2):215-7. PMID: 15057990.
      Citations:    
    233. Carmichael SL, Shaw GM, Yang W, Lammer EJ, Zhu H, Finnell RH. Limb deficiency defects, MSX1, and exposure to tobacco smoke. . 2004 Mar 15; 125A(3):285-9. PMID: 14994238.
      Citations:    
    234. Lammer EJ, Shaw GM, Iovannisci DM, Van Waes J, Finnell RH. Maternal smoking and the risk of orofacial clefts: Susceptibility with NAT1 and NAT2 polymorphisms. Epidemiology. 2004 Mar; 15(2):150-6. PMID: 15127906.
      Citations: 29     Fields:    Translation:Humans
    235. Zhu H, Wicker NJ, Volcik K, Zhang J, Shaw GM, Lammer EJ, Suarez L, Canfield M, Finnell RH. Promoter haplotype combinations for the human PDGFRA gene are associated with risk of neural tube defects. Mol Genet Metab. 2004 Feb; 81(2):127-32. PMID: 14741194.
      Citations: 8     Fields:    Translation:HumansCells
    236. Spiegelstein O, Merriweather MY, Wicker NJ, Finnell RH. Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice. Birth Defects Res A Clin Mol Teratol. 2003 Dec; 67(12):974-8. PMID: 14745917.
      Citations: 7     Fields:    Translation:Animals
    237. Spiegelstein O, Chatterjie N, Alexander G, Finnell RH. Teratogenicity of valproate conjugates with anticonvulsant activity in mice. Epilepsy Res. 2003 Dec; 57(2-3):145-52. PMID: 15013055.
      Citations: 1     Fields:    Translation:Animals
    238. Spiegelstein O, Lu X, Le XC, Troen A, Selhub J, Melnyk S, James SJ, Finnell RH. Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. Toxicol Lett. 2003 Nov 30; 145(2):167-74. PMID: 14581169.
      Citations: 14     Fields:    Translation:Animals
    239. Volcik KA, Shaw GM, Zhu H, Lammer EJ, Laurent C, Finnell RH. Associations between polymorphisms within the thymidylate synthase gene and spina bifida. Birth Defects Res A Clin Mol Teratol. 2003 Nov; 67(11):924-8. PMID: 14745930.
      Citations: 18     Fields:    Translation:Humans
    240. Shaw GM, Zhu H, Lammer EJ, Yang W, Finnell RH. Genetic variation of infant reduced folate carrier (A80G) and risk of orofacial and conotruncal heart defects. Am J Epidemiol. 2003 Oct 15; 158(8):747-52. PMID: 14561664.
      Citations: 17     Fields:    Translation:Humans
    241. Isoherranen N, Spiegelstein O, Bialer M, Zhang J, Merriweather M, Yagen B, Roeder M, Triplett AA, Schurig V, Finnell RH. Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity. Epilepsia. 2003 Oct; 44(10):1280-8. PMID: 14510821.
      Citations: 7     Fields:    Translation:Animals
    242. Heil SG, Kluijtmans LA, Spiegelstein O, Finnell RH, Blom HJ. Gene-specific monitoring of T7-based RNA amplification by real-time quantitative PCR. Biotechniques. 2003 Sep; 35(3):502-4, 506-8. PMID: 14513555.
      Citations: 2     Fields:    Translation:Cells
    243. Morin I, Devlin AM, Leclerc D, Sabbaghian N, Halsted CH, Finnell R, Rozen R. Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk. Mol Genet Metab. 2003 Jul; 79(3):197-200. PMID: 12855225.
      Citations: 17     Fields:    Translation:Humans
    244. Isoherranen N, Yagen B, Spiegelstein O, Finnell RH, Merriweather M, Woodhead JH, Wlodarczyk B, White HS, Bialer M. Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice. Br J Pharmacol. 2003 Jun; 139(4):755-64. PMID: 12812999.
      Citations: 4     Fields:    Translation:AnimalsCells
    245. Lundberg YW, Wing MJ, Xiong W, Zhao J, Finnell RH. Genetic dissection of hyperthermia-induced neural tube defects in mice. Birth Defects Res A Clin Mol Teratol. 2003 Jun; 67(6):409-13. PMID: 12962284.
      Citations: 5     Fields:    Translation:AnimalsPHPublic Health
    246. Isoherranen N, Yagen B, Spiegelstein O, Steinman A, Finnell RH, Bialer M. Gas chromatographic determination of novel valproyl taurinamide derivatives in mouse and dog plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 May 05; 788(1):125-36. PMID: 12668078.
      Citations: 1     Fields:    Translation:Animals
    247. Tang LS, Finnell RH. Neural and orofacial defects in Folp1 knockout mice [corrected]. Birth Defects Res A Clin Mol Teratol. 2003 Apr; 67(4):209-18. PMID: 12854656.
      Citations: 20     Fields:    Translation:Animals
    248. Shaw GM, Nelson V, Iovannisci DM, Finnell RH, Lammer EJ. Maternal occupational chemical exposures and biotransformation genotypes as risk factors for selected congenital anomalies. Am J Epidemiol. 2003 Mar 15; 157(6):475-84. PMID: 12631536.
      Citations: 12     Fields:    Translation:HumansPHPublic Health
    249. De Marco P, Calevo MG, Moroni A, Merello E, Raso A, Finnell RH, Zhu H, Andreussi L, Cama A, Capra V. Reduced folate carrier polymorphism (80A-->G) and neural tube defects. Eur J Hum Genet. 2003 Mar; 11(3):245-52. PMID: 12673279.
      Citations: 27     Fields:    Translation:Humans
    250. Zhu H, Wicker NJ, Shaw GM, Lammer EJ, Hendricks K, Suarez L, Canfield M, Finnell RH. Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects. Mol Genet Metab. 2003 Mar; 78(3):216-21. PMID: 12649067.
      Citations: 33     Fields:    Translation:HumansCells
    251. Volcik KA, Shaw GM, Lammer EJ, Zhu H, Finnell RH. Evaluation of infant methylenetetrahydrofolate reductase genotype, maternal vitamin use, and risk of high versus low level spina bifida defects. Birth Defects Res A Clin Mol Teratol. 2003 Mar; 67(3):154-7. PMID: 12797455.
      Citations: 6     Fields:    Translation:Humans
    252. Volcik KA, Shaw GM, Zhu H, Lammer EJ, Finnell RH. Risk factors for neural tube defects: associations between uncoupling protein 2 polymorphisms and spina bifida. Birth Defects Res A Clin Mol Teratol. 2003 Mar; 67(3):158-61. PMID: 12797456.
      Citations: 7     Fields:    Translation:Humans
    253. Zhu H, Barber R, Shaw GM, Lammer EJ, Finnell RH. Is Sonic hedgehog (SHH) a candidate gene for spina bifida? A pilot study. . 2003 Feb 15; 117A(1):87-8. PMID: 12548748.
      Citations:    
    254. Zhu H, Junker WM, Finnell RH, Brown S, Shaw GM, Lammer EJ, Canfield M, Hendricks K. Lack of association between ZIC2 and ZIC3 genes and the risk of neural tube defects (NTDs) in Hispanic populations. . 2003 Feb 01; 116A(4):414-5. PMID: 12522805.
      Citations:    
    255. Isoherranen N, Yagen B, Woodhead JH, Spiegelstein O, Blotnik S, Wilcox KS, Finnell RH, Bennett GD, White HS, Bialer M. Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents. Br J Pharmacol. 2003 Feb; 138(4):602-13. PMID: 12598414.
      Citations: 5     Fields:    Translation:AnimalsCells
    256. Finnell RH, Gould A, Spiegelstein O. Pathobiology and genetics of neural tube defects. Epilepsia. 2003; 44 Suppl 3:14-23. PMID: 12790882.
      Citations: 12     Fields:    Translation:HumansAnimals
    257. Volcik KA, Zhu H, Shaw GM, Lammer EJ, Finnell RH. Apolipoprotein E and apolipoprotein B genotypes and risk for spina bifida. Teratology. 2002 Nov; 66(5):257-9. PMID: 12397634.
      Citations: 2     Fields:    Translation:Humans
    258. Shaw GM, Nelson V, Carmichael SL, Lammer EJ, Finnell RH, Rosenquist TH. Maternal periconceptional vitamins: interactions with selected factors and congenital anomalies? Epidemiology. 2002 Nov; 13(6):625-30. PMID: 12410002.
      Citations: 14     Fields:    Translation:Humans
    259. Finnell RH, Junker WM, Wadman LK, Cabrera RM. Gene expression profiling within the developing neural tube. Neurochem Res. 2002 Oct; 27(10):1165-80. PMID: 12462415.
      Citations: 4     Fields:    Translation:Animals
    260. Rasmussen SA, Lammer EJ, Shaw GM, Finnell RH, McGehee RE, Gallagher M, Romitti PA, Murray JC. Integration of DNA sample collection into a multi-site birth defects case-control study. Teratology. 2002 Oct; 66(4):177-84. PMID: 12353214.
      Citations: 26     Fields:    Translation:HumansPHPublic Health
    261. Finnell RH, Spiegelstein O, Wlodarczyk B, Triplett A, Pogribny IP, Melnyk S, James JS. DNA methylation in Folbp1 knockout mice supplemented with folic acid during gestation. J Nutr. 2002 08; 132(8 Suppl):2457S-2461S. PMID: 12163711.
      Citations: 20     Fields:    Translation:AnimalsCells
    262. Shaw GM, Lammer EJ, Zhu H, Baker MW, Neri E, Finnell RH. Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida. Am J Med Genet. 2002 Feb 15; 108(1):1-6. PMID: 11857541.
      Citations: 33     Fields:    Translation:Humans
    263. Croen LA, Shaw GM, Barber RC, Baker MM, Finnell RH, Lammer EJ. Apolipoprotein B and apolipoprotein E genotypes and sporadic holoprosencephaly. Am J Med Genet. 2002 Feb 15; 108(1):75-7. PMID: 11857554.
      Citations:    Fields:    Translation:Humans
    264. Isoherranen N, White HS, Finnell RH, Yagen B, Woodhead JH, Bennett GD, Wilcox KS, Barton ME, Bialer M. Anticonvulsant profile and teratogenicity of N-methyl-tetramethylcyclopropyl carboxamide: a new antiepileptic drug. Epilepsia. 2002 Feb; 43(2):115-26. PMID: 11903457.
      Citations: 4     Fields:    Translation:Animals
    265. Gefrides LA, Bennett GD, Finnell RH. Effects of folate supplementation on the risk of spontaneous and induced neural tube defects in Splotch mice. Teratology. 2002 Feb; 65(2):63-9. PMID: 11857507.
      Citations: 6     Fields:    Translation:Animals
    266. Finnell RH, Waes JG, Eudy JD, Rosenquist TH. Molecular basis of environmentally induced birth defects. Annu Rev Pharmacol Toxicol. 2002; 42:181-208. PMID: 11807170.
      Citations: 23     Fields:    Translation:HumansAnimals
    267. Finnell RH, Shaw GM, Lammer EJ, Volcik KA. Does prenatal screening for 5,10-methylenetetrahydrofolate reductase (MTHFR) mutations in high-risk neural tube defect pregnancies make sense? Genet Test. 2002; 6(1):47-52. PMID: 12180076.
      Citations: 6     Fields:    Translation:HumansAnimals
    268. De Marco P, Calevo MG, Moroni A, Arata L, Merello E, Finnell RH, Zhu H, Andreussi L, Cama A, Capra V. Study of MTHFR and MS polymorphisms as risk factors for NTD in the Italian population. J Hum Genet. 2002; 47(6):319-24. PMID: 12111380.
      Citations: 27     Fields:    Translation:Humans
    269. Wlodarczyk B, Spiegelstein O, Gelineau-van Waes J, Vorce RL, Lu X, Le CX, Finnell RH. Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice. Toxicol Appl Pharmacol. 2001 Dec 15; 177(3):238-46. PMID: 11749123.
      Citations: 14     Fields:    Translation:Animals
    270. De Marco P, Calevo MG, Moroni A, Arata L, Merello E, Cama A, Finnell RH, Andreussi L, Capra V. Polymorphisms in genes involved in folate metabolism as risk factors for NTDs. Eur J Pediatr Surg. 2001 Dec; 11 Suppl 1:S14-7. PMID: 11813127.
      Citations: 10     Fields:    Translation:Humans
    271. Waes JG, Finnell RH. Importance of model organisms in understanding the biology and genetic basis of human nonsyndromic neural tube defects. Teratology. 2001 Oct; 64(4):177-80. PMID: 11598923.
      Citations:    Fields:    Translation:HumansAnimals
    272. Gelineau-van Waes J, Finnell RH. Genetics of neural tube defects. Semin Pediatr Neurol. 2001 Sep; 8(3):160-4. PMID: 11575845.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    273. Stegmann K, Boecker J, Richter B, Capra V, Finnell RH, Ngo ET, Strehl E, Ermert A, Koch MC. A screen for mutations in human homologues of mice exencephaly genes Tfap2alpha and Msx2 in patients with neural tube defects. Teratology. 2001 May; 63(5):167-75. PMID: 11320527.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    274. Rosenquist TH, Finnell RH. Genes, folate and homocysteine in embryonic development. Proc Nutr Soc. 2001 Feb; 60(1):53-61. PMID: 11310424.
      Citations: 14     Fields:    Translation:HumansAnimals
    275. Eudy JD, Spiegelstein O, Barber RC, Wlodarczyk BJ, Talbot J, Finnell RH. Identification and characterization of the human and mouse SLC19A3 gene: a novel member of the reduced folate family of micronutrient transporter genes. Mol Genet Metab. 2000 Dec; 71(4):581-90. PMID: 11136550.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    276. Spiegelstein O, Eudy JD, Finnell RH. Identification of two putative novel folate receptor genes in humans and mouse. Gene. 2000 Nov 27; 258(1-2):117-25. PMID: 11111049.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    277. De Marco P, Moroni A, Merello E, de Franchis R, Andreussi L, Finnell RH, Barber RC, Cama A, Capra V. Folate pathway gene alterations in patients with neural tube defects. Am J Med Genet. 2000 Nov 27; 95(3):216-23. PMID: 11102926.
      Citations: 6     Fields:    Translation:HumansCells
    278. Ruan Y, Peterson MH, Wauson EM, Waes JG, Finnell RH, Vorce RL. Folic acid protects SWV/Fnn embryo fibroblasts against arsenic toxicity. Toxicol Lett. 2000 Nov 20; 117(3):129-37. PMID: 11087978.
      Citations: 2     Fields:    Translation:AnimalsCells
    279. Finnell RH, Burn J. Effect of anti-epileptic drugs on intrauterine growth. Lancet. 2000 Nov 04; 356(9241):1537-8. PMID: 11075761.
      Citations: 1     Fields:    Translation:Humans
    280. Spiegelstein O, Yagen B, Bennett GD, Finnell RH, Blotnik S, Bialer M. Stereoselective pharmacokinetic analysis of valnoctamide, a CNS-active chiral amide analogue of valproic acid, in dogs, rats, and mice. Ther Drug Monit. 2000 Oct; 22(5):574-81. PMID: 11034263.
      Citations: 3     Fields:    Translation:HumansAnimals
    281. Joachims Z, Joachims HZ, Golz A, Hefer T, Finnell RH. Heredity in large vestibular aqueduct syndrome. J Otolaryngol. 2000 Aug; 29(4):244-6. PMID: 11003078.
      Citations:    Fields:    Translation:Humans
    282. Shaw GM, Todoroff K, Finnell RH, Lammer EJ. Spina bifida phenotypes in infants or fetuses of obese mothers. Teratology. 2000 May; 61(5):376-81. PMID: 10777833.
      Citations: 11     Fields:    Translation:Humans
    283. Barber R, Shalat S, Hendricks K, Joggerst B, Larsen R, Suarez L, Finnell R. Investigation of folate pathway gene polymorphisms and the incidence of neural tube defects in a Texas hispanic population. Mol Genet Metab. 2000 May; 70(1):45-52. PMID: 10833330.
      Citations: 18     Fields:    Translation:HumansCells
    284. Craig JC, Bennett GD, Miranda RC, Mackler SA, Finnell RH. Ribonucleotide reductase subunit R1: a gene conferring sensitivity to valproic acid-induced neural tube defects in mice. Teratology. 2000 Apr; 61(4):305-13. PMID: 10716750.
      Citations: 3     Fields:    Translation:AnimalsCells
    285. Shaw GM, Barber R, Todoroff K, Lammer EJ, Finnell RH. Microsatellites proximal to leptin and leptin receptor as risk factors for spina bifida. Teratology. 2000 Mar; 61(3):231-5. PMID: 10661913.
      Citations: 5     Fields:    Translation:HumansCells
    286. Finnell RH, Gelineau-van Waes J, Bennett GD, Barber RC, Wlodarczyk B, Shaw GM, Lammer EJ, Piedrahita JA, Eberwine JH. Genetic basis of susceptibility to environmentally induced neural tube defects. Ann N Y Acad Sci. 2000; 919:261-77. PMID: 11083116.
      Citations: 12     Fields:    Translation:HumansAnimals
    287. Bennett GD, Wlodarczyk B, Calvin JA, Craig JC, Finnell RH. Valproic acid-induced alterations in growth and neurotrophic factor gene expression in murine embryos [corrected]. Reprod Toxicol. 2000 Jan-Feb; 14(1):1-11. PMID: 10689198.
      Citations: 7     Fields:    Translation:AnimalsCells
    288. Spiegelstein O, Yagen B, Levy RH, Finnell RH, Bennett GD, Roeder M, Schurig V, Bialer M. Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid. Pharm Res. 1999 Oct; 16(10):1582-8. PMID: 10554101.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    289. Piedrahita JA, Oetama B, Bennett GD, van Waes J, Kamen BA, Richardson J, Lacey SW, Anderson RG, Finnell RH. Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nat Genet. 1999 Oct; 23(2):228-32. PMID: 10508523.
      Citations: 84     Fields:    Translation:AnimalsCells
    290. Rao VH, Singh RK, Delimont DC, Schaefer GB, Bridge JA, Neff JR, Sanger WG, Sappenfield JW, Buehler BA, Finnell RH. Interleukin-1beta upregulates MMP-9 expression in stromal cells of human giant cell tumor of bone. J Interferon Cytokine Res. 1999 Oct; 19(10):1207-17. PMID: 10547161.
      Citations: 4     Fields:    Translation:HumansCells
    291. McAlhany RE, Miranda RC, Finnell RH, West JR. Ethanol decreases Glial-Derived Neurotrophic Factor (GDNF) protein release but not mRNA expression and increases GDNF-stimulated Shc phosphorylation in the developing cerebellum. Alcohol Clin Exp Res. 1999 Oct; 23(10):1691-7. PMID: 10550003.
      Citations: 10     Fields:    Translation:AnimalsCells
    292. Shaw GM, Todoroff K, Finnell RH, Rozen R, Lammer EJ. Maternal vitamin use, infant C677T mutation in MTHFR, and isolated cleft palate risk. Am J Med Genet. 1999 Jul 02; 85(1):84-5. PMID: 10377018.
      Citations: 6     Fields:    Translation:Humans
    293. Trembath D, Sherbondy AL, Vandyke DC, Shaw GM, Todoroff K, Lammer EJ, Finnell RH, Marker S, Lerner G, Murray JC. Analysis of select folate pathway genes, PAX3, and human T in a Midwestern neural tube defect population. Teratology. 1999 May; 59(5):331-41. PMID: 10332959.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    294. Finnell RH, Bennett GD, Mather GG, Wlodarczyk B, Bajpai M, Levy RH. Effect of stiripentol dose on phenytoin-induced teratogenesis in a mouse model. Reprod Toxicol. 1999 Mar-Apr; 13(2):85-91. PMID: 10213515.
      Citations: 3     Fields:    Translation:Animals
    295. Finnell RH. Teratology: general considerations and principles. J Allergy Clin Immunol. 1999 Feb; 103(2 Pt 2):S337-42. PMID: 9949334.
      Citations: 16     Fields:    Translation:Humans
    296. Rao VH, Singh RK, Delimont DC, Finnell RH, Bridge JA, Neff JR, Garvin BP, Pickering DL, Sanger WG, Buehler BA, Schaefer GB. Transcriptional regulation of MMP-9 expression in stromal cells of human giant cell tumor of bone by tumor necrosis factor-alpha. Int J Oncol. 1999 Feb; 14(2):291-300. PMID: 9917505.
      Citations: 4     Fields:    Translation:HumansCells
    297. Barber RC, Lammer EJ, Shaw GM, Greer KA, Finnell RH. The role of folate transport and metabolism in neural tube defect risk. Mol Genet Metab. 1999 Jan; 66(1):1-9. PMID: 9973541.
      Citations: 8     Fields:    Translation:Humans
    298. Koebbe MJ, Golden JA, Bennett G, Finnell RH, Mackler SA. Effects of prenatal cocaine exposure on embryonic expression of sonic hedgehog. Teratology. 1999 Jan; 59(1):12-9. PMID: 9988878.
      Citations: 1     Fields:    Translation:Animals
    299. Shaw GM, Todoroff K, Finnell RH, Lammer EJ, Leclerc D, Gravel RA, Rozen R. Infant methionine synthase variants and risk for spina bifida. J Med Genet. 1999 Jan; 36(1):86-7. PMID: 9950377.
      Citations: 4     Fields:    Translation:Humans
    300. Barber RC, Bennett GD, Greer KA, Finnell RH. Expression patterns of folate binding proteins one and two in the developing mouse embryo. Mol Genet Metab. 1999 Jan; 66(1):31-9. PMID: 9973545.
      Citations: 10     Fields:    Translation:Animals
    301. Gelineau-van Waes J, Bennett GD, Finnell RH. Phenytoin-induced alterations in craniofacial gene expression. Teratology. 1999 Jan; 59(1):23-34. PMID: 9988880.
      Citations: 2     Fields:    Translation:Animals
    302. Shaw GM, Rozen R, Finnell RH, Todoroff K, Lammer EJ. Infant C677T mutation in MTHFR, maternal periconceptional vitamin use, and cleft lip. Am J Med Genet. 1998 Nov 16; 80(3):196-8. PMID: 9843036.
      Citations: 19     Fields:    Translation:Humans
    303. Hefer T, Joachims HZ, Carlson D, Finnell RH. [Factors associated with the etiology of congenital craniofacial anomalies--Part II]. Harefuah. 1998 Oct; 135(7-8):286-91. PMID: 9885676.
      Citations:    Fields:    Translation:Humans
    304. Hefer T, Joachims HZ, Carlson D, Finnell RH. [Factors associated with the etiology of congenital craniofacial anomalies--Part I]. Harefuah. 1998 Sep; 135(5-6):209-13. PMID: 9885638.
      Citations:    Fields:    Translation:Humans
    305. Shaw GM, Rozen R, Finnell RH, Wasserman CR, Lammer EJ. Maternal vitamin use, genetic variation of infant methylenetetrahydrofolate reductase, and risk for spina bifida. Am J Epidemiol. 1998 Jul 01; 148(1):30-7. PMID: 9663401.
      Citations: 18     Fields:    Translation:Humans
    306. Barber RC, Shaw GM, Lammer EJ, Greer KA, Biela TA, Lacey SW, Wasserman CR, Finnell RH. Lack of association between mutations in the folate receptor-alpha gene and spina bifida. Am J Med Genet. 1998 Apr 01; 76(4):310-7. PMID: 9545095.
      Citations: 9     Fields:    Translation:Humans
    307. Nair SM, Werkman TR, Craig J, Finnell R, Joëls M, Eberwine JH. Corticosteroid regulation of ion channel conductances and mRNA levels in individual hippocampal CA1 neurons. J Neurosci. 1998 Apr 01; 18(7):2685-96. PMID: 9502826.
      Citations: 13     Fields:    Translation:AnimalsCells
    308. Finnell RH, Greer KA, Barber RC, Piedrahita JA. Neural tube and craniofacial defects with special emphasis on folate pathway genes. Crit Rev Oral Biol Med. 1998; 9(1):38-53. PMID: 9488247.
      Citations: 10     Fields:    Translation:HumansAnimals
    309. Bennett GD, An J, Craig JC, Gefrides LA, Calvin JA, Finnell RH. Neurulation abnormalities secondary to altered gene expression in neural tube defect susceptible Splotch embryos. Teratology. 1998 Jan; 57(1):17-29. PMID: 9516748.
      Citations: 4     Fields:    Translation:Animals
    310. Amore BM, Kalhorn TF, Skiles GL, Hunter AP, Bennett GD, Finnell RH, Nelson SD, Slattery JT. Characterization of carbamazepine metabolism in a mouse model of carbamazepine teratogenicity. Drug Metab Dispos. 1997 Aug; 25(8):953-62. PMID: 9280403.
      Citations:    Fields:    Translation:Animals
    311. Finnell RH, Wlodarczyk BC, Craig JC, Piedrahita JA, Bennett GD. Strain-dependent alterations in the expression of folate pathway genes following teratogenic exposure to valproic acid in a mouse model. Am J Med Genet. 1997 Jun 13; 70(3):303-11. PMID: 9188671.
      Citations: 4     Fields:    Translation:Animals
    312. Bennett GD, Lau F, Calvin JA, Finnell RH. Phenytoin-induced teratogenesis: a molecular basis for the observed developmental delay during neurulation. Epilepsia. 1997 Apr; 38(4):415-23. PMID: 9118846.
      Citations: 8     Fields:    Translation:Animals
    313. Craig JC, Eberwine JH, Calvin JA, Wlodarczyk B, Bennett GD, Finnell RH. Developmental expression of morphoregulatory genes in the mouse embryo: an analytical approach using a novel technology. Biochem Mol Med. 1997 Apr; 60(2):81-91. PMID: 9169087.
      Citations: 3     Fields:    Translation:AnimalsCells
    314. Vacha SJ, Bennett GD, Mackler SA, Koebbe MJ, Finnell RH. Identification of a growth arrest specific (gas 5) gene by differential display as a candidate gene for determining susceptibility to hyperthermia-induced exencephaly in mice. Dev Genet. 1997; 21(3):212-22. PMID: 9397537.
      Citations: 3     Fields:    Translation:AnimalsCells
    315. Wlodarczyk BC, Craig JC, Bennett GD, Calvin JA, Finnell RH. Valproic acid-induced changes in gene expression during neurulation in a mouse model. Teratology. 1996 Dec; 54(6):284-97. PMID: 9098922.
      Citations: 10     Fields:    Translation:Animals
    316. Bennett GD, Amore BM, Finnell RH, Wlodarczyk B, Kalhorn TF, Skiles GL, Nelson SD, Slattery JT. Teratogenicity of carbamazepine-10, 11-epoxide and oxcarbazepine in the SWV mouse. J Pharmacol Exp Ther. 1996 Dec; 279(3):1237-42. PMID: 8968346.
      Citations: 3     Fields:    Translation:Animals
    317. Wlodarczyk BJ, Bennett GD, Calvin JA, Finnell RH. Arsenic-induced neural tube defects in mice: alterations in cell cycle gene expression. Reprod Toxicol. 1996 Nov-Dec; 10(6):447-54. PMID: 8946558.
      Citations: 15     Fields:    Translation:Animals
    318. Shalat SL, Walker DB, Finnell RH. Role of arsenic as a reproductive toxin with particular attention to neural tube defects. J Toxicol Environ Health. 1996 Jun 28; 48(3):253-72. PMID: 8656449.
      Citations: 13     Fields:    Translation:HumansAnimalsPHPublic Health
    319. Lillibridge JH, Amore BM, Slattery JT, Kalhorn TF, Nelson SD, Finnell RH, Bennett GD. Protein-reactive metabolites of carbamazepine in mouse liver microsomes. Drug Metab Dispos. 1996 May; 24(5):509-14. PMID: 8723729.
      Citations: 7     Fields:    Translation:AnimalsCells
    320. Wlodraczyk B, Bennett GD, Calvin JA, Craig JC, Finnell RH. Arsenic-induced alterations in embryonic transcription factor gene expression: implications for abnormal neural development. Dev Genet. 1996; 18(4):306-15. PMID: 8754282.
      Citations: 7     Fields:    Translation:Animals
    321. Mackler SA, Bennett GD, Tsuei VP, Finnell RH. Cocaine selectively alters neurotransmitter receptor mRNAs in mouse embryos. Reprod Toxicol. 1996 Jan-Feb; 10(1):37-42. PMID: 8998384.
      Citations: 1     Fields:    Translation:AnimalsCells
    322. Craig JC, Westerman ME, Dimichele L, Finnell RH. Screening for reproductive toxicity in Fundulus heteroclitus by genetic expression profiling. Biomarkers. 1996; 1(2):123-35. PMID: 23888923.
      Citations:    Fields:    
    323. Finnell RH, Bennett GD, Slattery JT, Amore BM, Bajpai M, Levy RH. Effect of treatment with phenobarbital and stiripentol on carbamazepine-induced teratogenicity and reactive metabolite formation. Teratology. 1995 Dec; 52(6):324-32. PMID: 8711619.
      Citations: 4     Fields:    Translation:AnimalsCells
    324. Raymond GV, Buehler BA, Finnell RH, Holmes LB. Anticonvulsant teratogenesis: 3. Possible metabolic basis. Teratology. 1995 Feb; 51(2):55-6. PMID: 7660321.
      Citations: 2     Fields:    Translation:HumansCells
    325. Eberwine J, Cao Y, Nair S, Miyashiro K, Mackler S, Finnell R, Surmeier J, Dichter M. Mechanisms of neuronal plasticity as analyzed at the single cell level. Prog Brain Res. 1995; 105:117-26. PMID: 7568870.
      Citations: 3     Fields:    Translation:AnimalsCells
    326. Taylor LE, Bennett GD, Finnell RH. Altered gene expression in murine branchial arches following in utero exposure to retinoic acid. J Craniofac Genet Dev Biol. 1995 Jan-Mar; 15(1):13-25. PMID: 7601910.
      Citations: 2     Fields:    Translation:AnimalsCells
    327. Shaw GM, Wasserman CR, O'Malley CD, Lammer EJ, Finnell RH. Orofacial clefts and maternal anticonvulsant use. Reprod Toxicol. 1995 Jan-Feb; 9(1):97-8. PMID: 8520135.
      Citations: 3     Fields:    Translation:Humans
    328. Buehler BA, Rao V, Finnell RH. Biochemical and molecular teratology of fetal hydantoin syndrome. Neurol Clin. 1994 Nov; 12(4):741-8. PMID: 7845340.
      Citations: 5     Fields:    Translation:HumansAnimals
    329. Musselman AC, Bennett GD, Greer KA, Eberwine JH, Finnell RH. Preliminary evidence of phenytoin-induced alterations in embryonic gene expression in a mouse model. Reprod Toxicol. 1994 Sep-Oct; 8(5):383-95. PMID: 7841657.
      Citations: 1     Fields:    Translation:AnimalsCells
    330. Finnell RH, Kerr BM, van Waes M, Steward RL, Levy RH. Protection from phenytoin-induced congenital malformations by coadministration of the antiepileptic drug stiripentol in a mouse model. Epilepsia. 1994 Jan-Feb; 35(1):141-8. PMID: 8112237.
      Citations: 2     Fields:    Translation:Animals
    331. Finnell RH, van Waes M, Musselman A, Kerr BM, Levy RH. Differences in the patterns of phenytoin-induced malformations following stiripentol coadministration in three inbred mouse strains. Reprod Toxicol. 1993 Sep-Oct; 7(5):439-48. PMID: 8274819.
      Citations: 2     Fields:    Translation:Animals
    332. Finnell RH, Van Waes M, Bennett GD, Eberwine JH. Lack of concordance between heat shock proteins and the development of tolerance to teratogen-induced neural tube defects. Dev Genet. 1993; 14(2):137-47. PMID: 8482018.
      Citations:    Fields:    Translation:AnimalsCells
    333. Finnell RH, Buehler BA, Kerr BM, Ager PL, Levy RH. Clinical and experimental studies linking oxidative metabolism to phenytoin-induced teratogenesis. Neurology. 1992 Apr; 42(4 Suppl 5):25-31. PMID: 1574173.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    334. Eberwine J, Yeh H, Miyashiro K, Cao Y, Nair S, Finnell R, Zettel M, Coleman P. Analysis of gene expression in single live neurons. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):3010-4. PMID: 1557406.
      Citations: 243     Fields:    Translation:AnimalsCells
    335. Finnell RH, Ager PL, Englen MD, Bennett GD. The heat shock response: potential to screen teratogens. Toxicol Lett. 1992 Jan; 60(1):39-52. PMID: 1539181.
      Citations: 2     Fields:    Translation:AnimalsCells
    336. Eberwine J, Spencer C, Miyashiro K, Mackler S, Finnell R. Complementary DNA synthesis in situ: methods and applications. Methods Enzymol. 1992; 216:80-100. PMID: 1479921.
      Citations: 19     Fields:    Translation:AnimalsCells
    337. Finnell RH, Mohl VK, Englen MD. In vitro analysis of the murine heat shock response: implications for reproductive toxicology. Toxicol Lett. 1991 Nov; 58(3):297-308. PMID: 1957325.
      Citations:    Fields:    Translation:AnimalsCells
    338. Finnell RH. Genetic differences in susceptibility to anticonvulsant drug-induced developmental defects. Pharmacol Toxicol. 1991 Oct; 69(4):223-7. PMID: 1956873.
      Citations: 4     Fields:    Translation:Humans
    339. Englen MD, Finnell RH. Strain differences in expression of the murine heat shock response: implications for abnormal neural development. Results Probl Cell Differ. 1991; 17:71-82. PMID: 1803425.
      Citations:    Fields:    Translation:AnimalsCells
    340. Finnell RH, Dansky LV. Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 1: Animal studies. Reprod Toxicol. 1991; 5(4):281-99. PMID: 1806138.
      Citations: 5     Fields:    Translation:Animals
    341. Dansky LV, Finnell RH. Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 2: Human studies. Reprod Toxicol. 1991; 5(4):301-35. PMID: 1806139.
      Citations: 16     Fields:    Translation:Animals
    342. Buehler BA, Delimont D, van Waes M, Finnell RH. Prenatal prediction of risk of the fetal hydantoin syndrome. N Engl J Med. 1990 May 31; 322(22):1567-72. PMID: 2336087.
      Citations: 27     Fields:    Translation:Humans
    343. Finnell RH, Toloyan S, van Waes M, Kalivas PW. Preliminary evidence for a cocaine-induced embryopathy in mice. Toxicol Appl Pharmacol. 1990 Apr; 103(2):228-37. PMID: 2330587.
      Citations: 1     Fields:    Translation:Animals
    344. Mohl VK, Bennett GD, Finnell RH. Genetic differences in the duration of the lymphocyte heat shock response in mice. Genetics. 1990 Apr; 124(4):949-55. PMID: 2323557.
      Citations: 1     Fields:    Translation:AnimalsCells
    345. Bennett GD, Mohl VK, Finnell RH. Embryonic and maternal heat shock responses to a teratogenic hyperthermic insult. Reprod Toxicol. 1990; 4(2):113-9. PMID: 2136025.
      Citations: 2     Fields:    Translation:AnimalsCells
    346. Finnell RH, Abbott LC, Taylor SM. The fetal hydantoin syndrome: answers from a mouse model. Reprod Toxicol. 1989; 3(2):127-33. PMID: 2520510.
      Citations: 1     Fields:    Translation:Animals
    347. Finnell RH, Bennett GD, Karras SB, Mohl VK. Common hierarchies of susceptibility to the induction of neural tube defects in mouse embryos by valproic acid and its 4-propyl-4-pentenoic acid metabolite. Teratology. 1988 Oct; 38(4):313-20. PMID: 3149038.
      Citations: 11     Fields:    Translation:Animals
    348. Finnell RH, Chernoff GF. Anagyrine-induced congenital defects. J Pediatr. 1988 Feb; 112(2):331. PMID: 3339518.
      Citations:    Fields:    Translation:Humans
    349. Finnell RH, Shields HE, Taylor SM, Chernoff GF. Strain differences in phenobarbital-induced teratogenesis in mice. Teratology. 1987 Apr; 35(2):177-85. PMID: 3603402.
      Citations: 6     Fields:    Translation:Animals
    350. Boehnke WH, Chernoff GF, Finnell RH. Investigation of the teratogenic effects of exercise on pregnancy outcome in mice. Teratog Carcinog Mutagen. 1987; 7(4):391-7. PMID: 2888217.
      Citations:    Fields:    Translation:Animals
    351. Taylor SM, Finnell RH. Effect of quinidine and tetrodotoxin on the activation of non-adrenergic nerves in guinea-pig trachealis muscle. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1987; 86(1):11-5. PMID: 2881704.
      Citations:    
    352. Finnell RH, Shields HE, Chernoff GF. Variable patterns in anticonvulsant drug-induced malformations in mice: comparisons of phenytoin and phenobarbital. Teratog Carcinog Mutagen. 1987; 7(6):541-9. PMID: 2893467.
      Citations: 1     Fields:    Translation:Animals
    353. Finnell RH, Baer JF. Congenital defects among the offspring of epileptic fathers: role of the genotype and phenytoin therapy in a mouse model. Epilepsia. 1986 Nov-Dec; 27(6):697-705. PMID: 3780606.
      Citations:    Fields:    Translation:HumansAnimals
    354. Abbott LC, Finnell RH, Chernoff GF, Parish SM, Gay CC. Crooked calf disease: a histological and histochemical examination of eight affected calves. Vet Pathol. 1986 Nov; 23(6):734-40. PMID: 3811138.
      Citations:    Fields:    Translation:Animals
    355. Willow M, Taylor SM, Catterall WA, Finnell RH. Down regulation of sodium channels in nerve terminals of spontaneously epileptic mice. Cell Mol Neurobiol. 1986 Jun; 6(2):213-20. PMID: 2425971.
      Citations:    Fields:    Translation:AnimalsCells
    356. Finnell RH, Moon SP, Abbott LC, Golden JA, Chernoff GF. Strain differences in heat-induced neural tube defects in mice. Teratology. 1986 Apr; 33(2):247-52. PMID: 3738820.
      Citations: 13     Fields:    Translation:Animals
    357. Liles WC, Taylor S, Finnell R, Lai H, Nathanson NM. Decreased muscarinic acetylcholine receptor number in the central nervous system of the tottering (tg/tg) mouse. J Neurochem. 1986 Mar; 46(3):977-82. PMID: 3950615.
      Citations: 1     Fields:    Translation:AnimalsCells
    358. Finnell RH, Mohl VK, Bennett GD, Taylor SM. Failure of epoxide formation to influence carbamazepine-induced teratogenesis in a mouse model. Teratog Carcinog Mutagen. 1986; 6(5):393-401. PMID: 2878505.
      Citations: 2     Fields:    Translation:Animals
    359. Taylor SM, Bennett GD, Abbott LC, Finnell RH. Seizure control following administration of anticonvulsant drugs in the quaking mouse. Eur J Pharmacol. 1985 Nov 26; 118(1-2):163-70. PMID: 3936724.
      Citations: 5     Fields:    Translation:Animals
    360. Finnell RH, Chernoff GF. Genetic background: the elusive component in the fetal hydantoin syndrome. Am J Med Genet. 1984 Nov; 19(3):459-62. PMID: 6507492.
      Citations: 2     Fields:    Translation:Humans
    361. Finnell RH, Chernoff GF. Variable patterns of malformation in the mouse fetal hydantoin syndrome. Am J Med Genet. 1984 Nov; 19(3):463-71. PMID: 6507493.
      Citations: 4     Fields:    Translation:Animals
    362. Finnell RH, DiLiberti JH. Hydantoin-induced teratogenesis: are arene oxide intermediates really responsible? Helv Paediatr Acta. 1983 May; 38(2):171-7. PMID: 6135678.
      Citations:    Fields:    Translation:Humans
    363. Finnell RH, Chernoff GF. Mouse fetal hydantoin syndrome: effects of maternal seizures. Epilepsia. 1982 Aug; 23(4):423-9. PMID: 7094908.
      Citations: 1     Fields:    Translation:Animals
    364. Finnell RH. Phenytoin-induced teratogenesis: a mouse model. Science. 1981 Jan 30; 211(4481):483-4. PMID: 7455686.
      Citations: 5     Fields:    Translation:Animals
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