TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wang W, Han D, Cai Q, Shen T, Dong B, Lewis MT, Wang R, Meng Y, Zhou W, Yi P, Creighton CJ, Moore DD, Yang F. MAPK4 promotes triple negative breast cancer growth and reduces tumor sensitivity to PI3K blockade. Nat Commun. 2022 Jan 11; 13(1):245. PMID: 35017531.
    2. Yi P, Yu X, Wang Z, O'Malley BW. Steroid receptor-coregulator transcriptional complexes: new insights from CryoEM. Essays Biochem. 2021 Dec 17; 65(6):857-866. PMID: 34061186.
      Citations: 1     Fields:    
    3. Yu W, Singh R, Wang Z, O'Malley BW, Yi P. The E3 ligase TRAF4 promotes IGF signaling by mediating atypical ubiquitination of IRS-1. J Biol Chem. 2021 Jan-Jun; 296:100739. PMID: 33991522.
      Citations:    Fields:    Translation:HumansCells
    4. Yu X, Yi P, Hamilton RA, Shen H, Chen M, Foulds CE, Mancini MA, Ludtke SJ, Wang Z, O'Malley BW. Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes. Mol Cell. 2020 09 03; 79(5):812-823.e4. PMID: 32668201.
      Citations: 12     Fields:    Translation:HumansCells
    5. Singh R, Karri D, Shen H, Shao J, Dasgupta S, Huang S, Edwards DP, Ittmann MM, O'Malley BW, Yi P. TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis. J Clin Invest. 2018 07 02; 128(7):3129-3143. PMID: 29715200.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    6. Panigrahi AK, Foulds CE, Lanz RB, Hamilton RA, Yi P, Lonard DM, Tsai MJ, Tsai SY, O'Malley BW. SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription. Mol Cell. 2018 05 17; 70(4):679-694.e7. PMID: 29775582.
      Citations: 13     Fields:    Translation:HumansCells
    7. Gates LA, Gu G, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, Jung SY, Malovannaya A, Li S, Shao J, Roeder RG, Ellis MJ, Qin J, Fuqua SAW, O'Malley BW, Foulds CE. Proteomic profiling identifies key coactivators utilized by mutant ERa proteins as potential new therapeutic targets. Oncogene. 2018 08; 37(33):4581-4598. PMID: 29748621.
      Citations: 22     Fields:    Translation:HumansCells
    8. Dasgupta S, Rajapakshe K, Zhu B, Nikolai BC, Yi P, Putluri N, Choi JM, Jung SY, Coarfa C, Westbrook TF, Zhang XH, Foulds CE, Tsai SY, Tsai MJ, O'Malley BW. Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. Nature. 2018 04; 556(7700):249-254. PMID: 29615789.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    9. Yi P, Wang Z, Feng Q, Chou CK, Pintilie GD, Shen H, Foulds CE, Fan G, Serysheva I, Ludtke SJ, Schmid MF, Hung MC, Chiu W, O'Malley BW. Structural and Functional Impacts of ER Coactivator Sequential Recruitment. Mol Cell. 2017 Sep 07; 67(5):733-743.e4. PMID: 28844863.
      Citations: 26     Fields:    Translation:HumansCells
    10. Yi P, Wang Z, Feng Q, Pintilie GD, Foulds CE, Lanz RB, Ludtke SJ, Schmid MF, Chiu W, O'Malley BW. Structure of a biologically active estrogen receptor-coactivator complex on DNA. Mol Cell. 2015 Mar 19; 57(6):1047-1058. PMID: 25728767.
      Citations: 51     Fields:    Translation:HumansCells
    11. Li B, Pi Z, Liu L, Zhang B, Huang X, Hu P, Chevet E, Yi P, Liu J. FGF-2 prevents cancer cells from ER stress-mediated apoptosis via enhancing proteasome-mediated Nck degradation. Biochem J. 2013 May 15; 452(1):139-45. PMID: 23448571.
      Citations: 15     Fields:    Translation:HumansCells
    12. Yi P, Xia W, Wu RC, Lonard DM, Hung MC, O'Malley BW. SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. Genes Dev. 2013 Feb 01; 27(3):274-87. PMID: 23388826.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    13. Yi P, Higa A, Taouji S, Bexiga MG, Marza E, Arma D, Castain C, Le Bail B, Simpson JC, Rosenbaum J, Balabaud C, Bioulac-Sage P, Blanc JF, Chevet E. Sorafenib-mediated targeting of the AAA? ATPase p97/VCP leads to disruption of the secretory pathway, endoplasmic reticulum stress, and hepatocellular cancer cell death. Mol Cancer Ther. 2012 Dec; 11(12):2610-20. PMID: 23041544.
      Citations: 34     Translation:HumansCells
    14. Li B, Yi P, Zhang B, Xu C, Liu Q, Pi Z, Xu X, Chevet E, Liu J. Differences in endoplasmic reticulum stress signalling kinetics determine cell survival outcome through activation of MKP-1. Cell Signal. 2011 Jan; 23(1):35-45. PMID: 20727407.
      Citations: 27     Fields:    Translation:AnimalsCells
    15. Yi P, Nguyên DT, Higa-Nishiyama A, Auguste P, Bouchecareilh M, Dominguez M, Bielmann R, Palcy S, Liu JF, Chevet E. MAPK scaffolding by BIT1 in the Golgi complex modulates stress resistance. J Cell Sci. 2010 Apr 01; 123(Pt 7):1060-72. PMID: 20197408.
      Citations: 7     Fields:    Translation:AnimalsCells
    16. Fu X, Yucer N, Liu S, Li M, Yi P, Mu JJ, Yang T, Chu J, Jung SY, O'Malley BW, Gu W, Qin J, Wang Y. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4579-84. PMID: 20173098.
      Citations: 34     Fields:    Translation:HumansCells
    17. Long W, Yi P, Amazit L, LaMarca HL, Ashcroft F, Kumar R, Mancini MA, Tsai SY, Tsai MJ, O'Malley BW. SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell. 2010 Feb 12; 37(3):321-32. PMID: 20159552.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    18. Han J, Li L, Hu J, Yu L, Zheng Y, Guo J, Zheng X, Yi P, Zhou Y. Epidermal growth factor stimulates human trophoblast cell migration through Rho A and Rho C activation. Endocrinology. 2010 Apr; 151(4):1732-42. PMID: 20150581.
      Citations: 22     Fields:    Translation:HumansCells
    19. Yi P, Feng Q, Amazit L, Lonard DM, Tsai SY, Tsai MJ, O'Malley BW. Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell. 2008 Feb 29; 29(4):465-76. PMID: 18313384.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    20. Feng Q, Yi P, Wong J, O'Malley BW. Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly. Mol Cell Biol. 2006 Nov; 26(21):7846-57. PMID: 16923966.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    21. Yi P, Wu RC, Sandquist J, Wong J, Tsai SY, Tsai MJ, Means AR, O'Malley BW. Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol. 2005 Nov; 25(21):9687-99. PMID: 16227615.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    22. Wu RC, Qin J, Yi P, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell. 2004 Sep 24; 15(6):937-49. PMID: 15383283.
      Citations: 130     Fields:    Translation:HumansAnimalsCells
    23. Li X, Huang J, Yi P, Bambara RA, Hilf R, Muyan M. Single-chain estrogen receptors (ERs) reveal that the ERalpha/beta heterodimer emulates functions of the ERalpha dimer in genomic estrogen signaling pathways. Mol Cell Biol. 2004 Sep; 24(17):7681-94. PMID: 15314175.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    24. Huang J, Li X, Yi P, Hilf R, Bambara RA, Muyan M. Targeting estrogen responsive elements (EREs): design of potent transactivators for ERE-containing genes. Mol Cell Endocrinol. 2004 Apr 15; 218(1-2):65-78. PMID: 15130512.
      Citations: 14     Fields:    Translation:AnimalsCells
    25. Yi P, Bhagat S, Hilf R, Bambara RA, Muyan M. Differences in the abilities of estrogen receptors to integrate activation functions are critical for subtype-specific transcriptional responses. Mol Endocrinol. 2002 Aug; 16(8):1810-27. PMID: 12145336.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    26. Sathya G, Yi P, Bhagat S, Bambara RA, Hilf R, Muyan M. Structural regions of ERalpha critical for synergistic transcriptional responses contain co-factor interacting surfaces. Mol Cell Endocrinol. 2002 Jun 28; 192(1-2):171-85. PMID: 12088878.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    27. Yi P, Driscoll MD, Huang J, Bhagat S, Hilf R, Bambara RA, Muyan M. The effects of estrogen-responsive element- and ligand-induced structural changes on the recruitment of cofactors and transcriptional responses by ER alpha and ER beta. Mol Endocrinol. 2002 Apr; 16(4):674-93. PMID: 11923465.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    28. Yi PL, Chang FC, Tsai JJ, Hung CR, Gean PW. The involvement of metabotropic glutamate receptors in long-term depression of N-methyl-D-aspartate receptor-mediated synaptic potential in the rat hippocampus. Neurosci Lett. 1995 Feb 13; 185(3):207-10. PMID: 7753492.
      Citations: 2     Fields:    Translation:AnimalsCells
    29. Gean PW, Huang CC, Kuo JR, Lin JH, Yi PL, Tsai JJ. Analysis of carbamazepine's anticonvulsant actions in hippocampal and amygdaloid slices of the rat. Chin J Physiol. 1993; 36(4):199-204. PMID: 7912663.
      Citations: 1     Fields:    Translation:AnimalsCells
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