OLIVE ECKSTEIN

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 BATES
Houston, TX 77030
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    Collapse Biography 
    Collapse awards and honors
    2019Jon Pritchard Award, Nikolas Symposia on the Histiocytoses
    2017 - 2020NIH K12 Pediatric Oncology Clinical Research Grant, Baylor College of Medicine
    2016 - 2021NIH LRP Scholar, National Institutes of Health (NIH)-NCATS (National Center for Advancing Translational Sciences)
    2016Rising Star in Oncology, Society for Translational Oncology
    2012Excellent Tumor Board Presentation, Texas Children's Cancer and Hematology Centers
    2010Harvard Medical Student Teaching Award, Boston Children's Hospital/Harvard Medical School
    2006Gold Humanism in Medicine Society, Arnold P. Gold Foundation
    2006Alpha Omega Alpha Honor Society, Alpha Omega Alpha

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    K12CA090433     (BLANEY, SUSAN M.)Apr 1, 2001 - Jun 30, 2022
    NIH
    Pediatric Oncology Clinical Research Training Program
    Role: Co-Investigator

    T32DK060445     (GOODELL, MARGARET A.)Sep 30, 2002 - Jun 30, 2024
    NIH
    Hematology Training Program
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Forbes LR, Eckstein OS, Gulati N, Peckham-Gregory EC, Ozuah NW, Lubega J, El-Mallawany NK, Agrusa JE, Poli MC, Vogel TP, Chaimowitz NS, Rider NL, Mace EM, Orange JS, Caldwell JW, Aldave-Becerra JC, Jolles S, Saettini F, Chong HJ, Stray-Pedersen A, Heslop HE, Kamdar KY, Rouce RH, Muzny DM, Jhangiani SN, Gibbs RA, Coban-Akdemir ZH, Lupski JR, McClain KL, Allen CE, Chinn IK. Genetic errors of immunity distinguish pediatric nonmalignant lymphoproliferative disorders. J Allergy Clin Immunol. 2021 Jul 28. PMID: 34329649.
      Citations:    Fields:    
    2. Sengal A, Velazquez J, Hahne M, Burke TM, Abhyankar H, Reyes R, Olea W, Scull B, Eckstein OS, Bigenwald C, Bollard CM, Yu W, Merad M, McClain KL, Allen CE, Chakraborty R. Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH. Blood. 2021 04 01; 137(13):1777-1791. PMID: 33075814.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    3. Naik S, Eckstein O, Sasa G, Heslop HE, Krance RA, Allen C, Martinez C. Incorporation of thiotepa in a reduced intensity conditioning regimen may improve engraftment after transplant for HLH. Br J Haematol. 2020 03; 188(6):e84-e87. PMID: 31989587.
      Citations: 2     Fields:    Translation:Humans
    4. Lim KPH, Milne P, Poidinger M, Duan K, Lin H, McGovern N, Abhyankar H, Zinn D, Burke TM, Eckstein OS, Chakraborty R, Sengal A, Scull B, Newell E, Merad M, McClain KL, Man TK, Ginhoux F, Collin M, Allen CE. Circulating CD1c+ myeloid dendritic cells are potential precursors to LCH lesion CD1a+CD207+ cells. Blood Adv. 2020 01 14; 4(1):87-99. PMID: 31899802.
      Citations: 1     Fields:    Translation:HumansCells
    5. Jordan MB, Allen CE, Greenberg J, Henry M, Hermiston ML, Kumar A, Hines M, Eckstein O, Ladisch S, Nichols KE, Rodriguez-Galindo C, Wistinghausen B, McClain KL. Challenges in the diagnosis of hemophagocytic lymphohistiocytosis: Recommendations from the North American Consortium for Histiocytosis (NACHO). Pediatr Blood Cancer. 2019 11; 66(11):e27929. PMID: 31339233.
      Citations: 29     Fields:    Translation:Humans
    6. Zinn DJ, Eckstein O, Olsen ML, Allen CE, McClain KL. Thalidomide, A Rational Agent for Treatment of Multicentric Reticulohistiocytosis. Dermatol Case Rep. 2019; 4(1). PMID: 32529194.
      Citations:    
    7. Celebi N, Vallejo JG, Eckstein OS, Geer J, Punia JN, Elenberg E. Persistent fever in a pediatric renal transplant patient: Questions. Pediatr Nephrol. 2019 05; 34(5):823-824. PMID: 30570688.
      Citations:    Fields:    Translation:Humans
    8. Flores Legarreta A, Eckstein O, Burke TM, McClain KL. Anti TNF-a therapy in patients with relapsed and refractory Langerhans cell histiocytosis: a phase II study. Pediatr Hematol Oncol. 2018 Aug - Sep; 35(5-6):362-368. PMID: 30468406.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    9. Forbes LR, Vogel TP, Cooper MA, Castro-Wagner J, Schussler E, Weinacht KG, Plant AS, Su HC, Allenspach EJ, Slatter M, Abinun M, Lilic D, Cunningham-Rundles C, Eckstein O, Olbrich P, Guillerman RP, Patel NC, Demirdag YY, Zerbe C, Freeman AF, Holland SM, Szabolcs P, Gennery A, Torgerson TR, Milner JD, Leiding JW. Jakinibs for the treatment of immune dysregulation in patients with gain-of-function signal transducer and activator of transcription 1 (STAT1) or STAT3 mutations. J Allergy Clin Immunol. 2018 11; 142(5):1665-1669. PMID: 30092289.
      Citations: 39     Fields:    Translation:Humans
    10. Chinn IK, Eckstein OS, Peckham-Gregory EC, Goldberg BR, Forbes LR, Nicholas SK, Mace EM, Vogel TP, Abhyankar HA, Diaz MI, Heslop HE, Krance RA, Martinez CA, Nguyen TC, Bashir DA, Goldman JR, Stray-Pedersen A, Pedroza LA, Poli MC, Aldave-Becerra JC, McGhee SA, Al-Herz W, Chamdin A, Coban-Akdemir ZH, Jhangiani SN, Muzny DM, Cao TN, Hong DN, Gibbs RA, Lupski JR, Orange JS, McClain KL, Allen CE. Genetic and mechanistic diversity in pediatric hemophagocytic lymphohistiocytosis. Blood. 2018 07 05; 132(1):89-100. PMID: 29632024.
      Citations: 37     Fields:    Translation:HumansCTClinical Trials
    11. Eckstein O, Allen C, McClain K. Rudolph's Pediatrics, Editor-in-Chief Mark Kline. Histiocytic Disorders (Chapter 459). 2018.
    12. Chakraborty R, Hampton OA, Abhyankar H, Zinn DJ, Grimes A, Skull B, Eckstein O, Mahmood N, Wheeler DA, Lopez-Terrada D, Peters TL, Hicks JM, Elghetany T, Krance R, Poulikakos PI, Merad M, McClain KL, Allen CE, Parsons DW. Activating MAPK1 (ERK2) mutation in an aggressive case of disseminated juvenile xanthogranuloma. Oncotarget. 2017 Jul 11; 8(28):46065-46070. PMID: 28512266.
      Citations: 7     Fields:    Translation:HumansCells
    13. McClain KL, Eckstein O. UpToDate. Clinical features and diagnosis of hemophagocytic lymphohistiocytosis. 2017. View Publication.
    14. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 28935696.
      Citations: 4     Fields:    Translation:Humans
    15. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 29624648.
      Citations: 13     Fields:    Translation:HumansCells
    16. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 27896915.
      Citations: 4     Fields:    Translation:Humans
    17. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 30596314.
      Citations:    Fields:    Translation:Humans
    18. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 30570689.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    19. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 30718231.
      Citations: 11     Fields:    Translation:HumansCells
    20. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 31050187.
      Citations: 1     Fields:    Translation:HumansCells
    21. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 32511892.
      Citations: 2     Fields:    Translation:Humans
    22. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 33276546.
      Citations: 1     
    23. Zinn DJ, Grimes AB, Lin H, Eckstein O, Allen CE, McClain KL. Hydroxyurea: a new old therapy for Langerhans cell histiocytosis. Blood. 2016 11 17; 128(20):2462-2465. PMID: 27688802.
      Citations: 5     Fields:    Translation:Humans
    24. Eckstein OS, Wang L, Punia JN, Kornblau SM, Andreeff M, Wheeler DA, Goodell MA, Rau RE. Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes. Exp Hematol. 2016 08; 44(8):740-4. PMID: 27208809.
      Citations: 13     Fields:    Translation:HumansCells
    25. Eckstein O, Stemmer-Rachamimov A, Nunes F, Hoch D, Ojemann R, MacCollin M. Multiple meningiomas in brain and lung due to acquired mutation of the NF2 gene. Neurology. 2004 May 25; 62(10):1904-5. PMID: 15159511.
      Citations: 2     Fields:    Translation:HumansCells
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