TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
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    R01HL076246     (FRANGOGIANNIS, NIKOLAOS G)Apr 1, 2004 - Jan 31, 2024
    Chemokines in healing myocardial infarction
    Role: Principal Investigator

    R01HL085440     (FRANGOGIANNIS, NIKOLAOS G)Jun 1, 2006 - May 31, 2021
    Resolution of inflammation in healing myocardial infarcts
    Role: Principal Investigator

    R01HL149407     (FRANGOGIANNIS, NIKOLAOS G)Apr 3, 2020 - Mar 31, 2024
    Regulation of the TGF-beta superfamily in the remodeling and failing heart
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lindsey ML, Brunt KR, Kirk JA, Kleinbongard P, Calvert JW, de Castro Brás LE, DeLeon-Pennell KY, Del Re DP, Frangogiannis NG, Frantz S, Gumina RJ, Halade GV, Jones SP, Ritchie RH, Spinale FG, Thorp EB, Ripplinger CM, Kassiri Z. Guidelines for in vivo mouse models of myocardial infarction. Am J Physiol Heart Circ Physiol. 2021 Dec 01; 321(6):H1056-H1073. PMID: 34623181.
      Citations:    Fields:    
    2. Frangogiannis NG. Platelet-derived growth factor (PDGF) therapy in myocardial infarction: Challenges and opportunities. Int J Cardiol. 2021 10 15; 341:74-75. PMID: 34418517.
      Citations:    Fields:    Translation:Humans
    3. Tuleta I, Frangogiannis NG. Fibrosis of the diabetic heart: Clinical significance, molecular mechanisms, and therapeutic opportunities. Adv Drug Deliv Rev. 2021 09; 176:113904. PMID: 34331987.
      Citations: 1     Fields:    
    4. Lindsey ML, de Castro Brás LE, DeLeon-Pennell KY, Frangogiannis NG, Halade GV, O'Meara CC, Spinale FG, Kassiri Z, Kirk JA, Kleinbongard P, Ripplinger CM, Brunt KR. Reperfused vs. nonreperfused myocardial infarction: when to use which model. Am J Physiol Heart Circ Physiol. 2021 07 01; 321(1):H208-H213. PMID: 34114891.
      Citations: 1     Fields:    Translation:Animals
    5. Frangogiannis NG. Cardiac fibrosis. Cardiovasc Res. 2021 05 25; 117(6):1450-1488. PMID: 33135058.
      Citations: 10     Fields:    
    6. Hanna A, Shinde AV, Li R, Alex L, Humeres C, Balasubramanian P, Frangogiannis NG. Collagen denaturation in the infarcted myocardium involves temporally distinct effects of MT1-MMP-dependent proteolysis and mechanical tension. Matrix Biol. 2021 05; 99:18-42. PMID: 34048934.
      Citations: 1     Fields:    
    7. Marian AJ, Asatryan B, Bolli R, Cheedipudi SM, Dhalla NS, Finkel T, Frangogiannis NG, Gurha P, Belmonte JCI, Hare JM, Hong K, Kirshenbaum LA, Lee RT, Leesar MA, Libby P, Madonna R, Nagueh SF, Roberts R, Rosenzweig A, Rouhi L, Sadoshima J, Sussman MA, Taffet GE, Tanaka H, Torella D, Wang Y, Wang DW. Editors' Preamble to The Journal of Cardiovascular Aging. J Cardiovasc Aging. 2021; 1. PMID: 34327514.
    8. Tuleta I, Frangogiannis NG. Diabetic fibrosis. Biochim Biophys Acta Mol Basis Dis. 2021 04 01; 1867(4):166044. PMID: 33378699.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    9. Hanna A, Humeres C, Frangogiannis NG. The role of Smad signaling cascades in cardiac fibrosis. Cell Signal. 2021 01; 77:109826. PMID: 33160018.
      Citations: 5     Fields:    
    10. Frangogiannis NG. Fact and Fiction About Fibroblast to Endothelium Conversion: Semantics and Substance of Cellular Identity. Circulation. 2020 10 27; 142(17):1663-1666. PMID: 33104399.
      Citations: 1     Fields:    Translation:HumansCells
    11. Li R, Frangogiannis NG. Chemokines in cardiac fibrosis. Curr Opin Physiol. 2021 Feb; 19:80-91. PMID: 33195890.
      Citations: 3     
    12. Frangogiannis NG. The significance of COVID-19-associated myocardial injury: how overinterpretation of scientific findings can fuel media sensationalism and spread misinformation. Eur Heart J. 2020 10 14; 41(39):3836-3838. PMID: 33006608.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    13. Hanna A, Frangogiannis NG. Inflammatory Cytokines and Chemokines as Therapeutic Targets in Heart Failure. Cardiovasc Drugs Ther. 2020 12; 34(6):849-863. PMID: 32902739.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    14. Hanna A, Shinde AV, Frangogiannis NG. Validation of diagnostic criteria and histopathological characterization of cardiac rupture in the mouse model of nonreperfused myocardial infarction. Am J Physiol Heart Circ Physiol. 2020 11 01; 319(5):H948-H964. PMID: 32886000.
      Citations: 2     Fields:    Translation:AnimalsCells
    15. Chen B, Frangogiannis NG. Chemokines in Myocardial Infarction. J Cardiovasc Transl Res. 2021 02; 14(1):35-52. PMID: 32415537.
      Citations: 10     Fields:    
    16. de Castro Brás LE, Frangogiannis NG. Extracellular matrix-derived peptides in tissue remodeling and fibrosis. Matrix Biol. 2020 09; 91-92:176-187. PMID: 32438055.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    17. Frangogiannis NG, Kovacic JC. Extracellular Matrix in Ischemic Heart Disease, Part 4/4: JACC Focus Seminar. J Am Coll Cardiol. 2020 05 05; 75(17):2219-2235. PMID: 32354387.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    18. Huang S, Chen B, Humeres C, Alex L, Hanna A, Frangogiannis NG. The role of Smad2 and Smad3 in regulating homeostatic functions of fibroblasts in vitro and in adult mice. Biochim Biophys Acta Mol Cell Res. 2020 07; 1867(7):118703. PMID: 32179057.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    19. Frangogiannis N. Transforming growth factor-ß in tissue fibrosis. J Exp Med. 2020 03 02; 217(3):e20190103. PMID: 32997468.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    20. Frangogiannis NG. Monocyte subsets as predictors of adverse events in patients with atherosclerosis. Hellenic J Cardiol. 2019 Sep - Oct; 60(5):322-323. PMID: 31846698.
      Citations:    Fields:    Translation:HumansCells
    21. Frangogiannis NG. Editorial commentary: Myocardial fibrosis in genetic cardiomyopathies: A cause of dysfunction, or simply an epiphenomenon? Trends Cardiovasc Med. 2020 08; 30(6):362-363. PMID: 31653486.
      Citations:    Fields:    Translation:Humans
    22. Frangogiannis NG. How do endosomal Toll-like receptors sense and extend ischaemic myocardial injury? Cardiovasc Res. 2019 10 01; 115(12):1687-1689. PMID: 31099398.
      Citations:    Fields:    Translation:HumansCells
    23. Hanna A, Frangogiannis NG. The Role of the TGF-ß Superfamily in Myocardial Infarction. Front Cardiovasc Med. 2019; 6:140. PMID: 31620450.
      Citations: 45     
    24. Frangogiannis NG. S100A8/A9 as a therapeutic target in myocardial infarction: cellular mechanisms, molecular interactions, and translational challenges. Eur Heart J. 2019 08 21; 40(32):2724-2726. PMID: 31334753.
      Citations: 2     Fields:    Translation:HumansCells
    25. Hanna A, Frangogiannis NG. The cell biological basis for primary unloading in acute myocardial infarction. Int J Cardiol. 2019 10 15; 293:45-47. PMID: 31296394.
      Citations:    Fields:    Translation:Humans
    26. Humeres C, Frangogiannis NG. Fibroblasts in the Infarcted, Remodeling, and Failing Heart. JACC Basic Transl Sci. 2019 Jun; 4(3):449-467. PMID: 31312768.
      Citations: 56     
    27. Frangogiannis NG. The Extracellular Matrix in Ischemic and Nonischemic Heart Failure. Circ Res. 2019 06 21; 125(1):117-146. PMID: 31219741.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    28. Andreadou I, Cabrera-Fuentes HA, Devaux Y, Frangogiannis NG, Frantz S, Guzik T, Liehn EA, Gomes CPC, Schulz R, Hausenloy DJ. Immune cells as targets for cardioprotection: new players and novel therapeutic opportunities. Cardiovasc Res. 2019 06 01; 115(7):1117-1130. PMID: 30825305.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    29. Chen B, Huang S, Su Y, Wu YJ, Hanna A, Brickshawana A, Graff J, Frangogiannis NG. Macrophage Smad3 Protects the Infarcted Heart, Stimulating Phagocytosis and Regulating Inflammation. Circ Res. 2019 06 21; 125(1):55-70. PMID: 31092129.
      Citations: 25     Fields:    Translation:AnimalsCells
    30. Frangogiannis NG. Can Myocardial Fibrosis Be Reversed? J Am Coll Cardiol. 2019 05 14; 73(18):2283-2285. PMID: 31072571.
      Citations: 7     Fields:    Translation:HumansCells
    31. Huang S, Chen B, Su Y, Alex L, Humeres C, Shinde AV, Conway SJ, Frangogiannis NG. Distinct roles of myofibroblast-specific Smad2 and Smad3 signaling in repair and remodeling of the infarcted heart. J Mol Cell Cardiol. 2019 07; 132:84-97. PMID: 31085202.
      Citations: 16     Fields:    Translation:AnimalsCells
    32. Alex L, Frangogiannis NG. Pericytes in the infarcted heart. Vasc Biol. 2019; 1(1):H23-H31. PMID: 32923950.
      Citations: 3     
    33. Russo I, Cavalera M, Huang S, Su Y, Hanna A, Chen B, Shinde AV, Conway SJ, Graff J, Frangogiannis NG. Protective Effects of Activated Myofibroblasts in the Pressure-Overloaded Myocardium Are Mediated Through Smad-Dependent Activation of a Matrix-Preserving Program. Circ Res. 2019 04 12; 124(8):1214-1227. PMID: 30686120.
      Citations: 36     Fields:    Translation:AnimalsCells
    34. Chen B, Brickshawana A, Frangogiannis NG. The Functional Heterogeneity of Resident Cardiac Macrophages in Myocardial InjuryCCR2+ Cells Promote Inflammation, Whereas CCR2- Cells Protect. Circ Res. 2019 01 18; 124(2):183-185. PMID: 30653429.
      Citations: 6     Fields:    Translation:HumansCells
    35. Frangogiannis NG. Protean Functions and Phenotypic Plasticity of Regulatory T Cells in Chronic Ischemic Heart Failure. Circulation. 2019 01 08; 139(2):222-225. PMID: 30615501.
      Citations: 1     Fields:    Translation:HumansCells
    36. Chen B, Huang S, Frangogiannis NG. Aging, cardiac repair and Smad3. Aging (Albany NY). 2018 09 20; 10(9):2230-2232. PMID: 30243021.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    37. Frangogiannis NG. Cardiac fibrosis: Cell biological mechanisms, molecular pathways and therapeutic opportunities. Mol Aspects Med. 2019 02; 65:70-99. PMID: 30056242.
      Citations: 124     Fields:    Translation:HumansAnimalsCells
    38. Alex L, Russo I, Holoborodko V, Frangogiannis NG. Characterization of a mouse model of obesity-related fibrotic cardiomyopathy that recapitulates features of human heart failure with preserved ejection fraction. Am J Physiol Heart Circ Physiol. 2018 10 01; 315(4):H934-H949. PMID: 30004258.
      Citations: 41     Translation:HumansAnimalsCells
    39. Frangogiannis NG. Targeting mitochondrial calcium transport in myocardial infarction. Hellenic J Cardiol. 2018 Jul - Aug; 59(4):223-225. PMID: 29940221.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    40. Chen B, Frangogiannis NG. The Role of Macrophages in Nonischemic Heart Failure. JACC Basic Transl Sci. 2018 Apr; 3(2):245-248. PMID: 30062210.
      Citations: 8     
    41. Frangogiannis NG. Galectin-3 in the fibrotic response: Cellular targets and molecular mechanisms. Int J Cardiol. 2018 05 01; 258:226-227. PMID: 29544937.
      Citations: 3     Fields:    Translation:Humans
    42. Huang S, Frangogiannis NG. Anti-inflammatory therapies in myocardial infarction: failures, hopes and challenges. Br J Pharmacol. 2018 05; 175(9):1377-1400. PMID: 29394499.
      Citations: 41     Fields:    Translation:HumansAnimals
    43. Kirk JA, Frangogiannis NG. Galectin-3 in the pathogenesis of heart failure: a causative mediator or simply a biomarker? Am J Physiol Heart Circ Physiol. 2018 06 01; 314(6):H1256-H1258. PMID: 29498533.
      Citations: 2     Fields:    Translation:Humans
    44. Shinde AV, Su Y, Palanski BA, Fujikura K, Garcia MJ, Frangogiannis NG. Pharmacologic inhibition of the enzymatic effects of tissue transglutaminase reduces cardiac fibrosis and attenuates cardiomyocyte hypertrophy following pressure overload. J Mol Cell Cardiol. 2018 04; 117:36-48. PMID: 29481819.
      Citations: 8     Fields:    Translation:AnimalsCells
    45. Alex L, Frangogiannis NG. The Cellular Origin of Activated Fibroblasts in the Infarcted and Remodeling Myocardium. Circ Res. 2018 02 16; 122(4):540-542. PMID: 29449358.
      Citations: 11     Fields:    Translation:HumansCells
    46. Frangogiannis NG. Cell therapy for peripheral artery disease. Curr Opin Pharmacol. 2018 04; 39:27-34. PMID: 29452987.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    47. Lindsey ML, Bolli R, Canty JM, Du XJ, Frangogiannis NG, Frantz S, Gourdie RG, Holmes JW, Jones SP, Kloner RA, Lefer DJ, Liao R, Murphy E, Ping P, Przyklenk K, Recchia FA, Schwartz Longacre L, Ripplinger CM, Van Eyk JE, Heusch G. Guidelines for experimental models of myocardial ischemia and infarction. Am J Physiol Heart Circ Physiol. 2018 04 01; 314(4):H812-H838. PMID: 29351451.
      Citations: 130     Translation:AnimalsCells
    48. Frangogiannis NG. Cell biological mechanisms in regulation of the post-infarction inflammatory response. Curr Opin Physiol. 2018 Feb; 1:7-13. PMID: 29552674.
      Citations: 16     
    49. Shinde AV, Frangogiannis NG. Tissue transglutaminase in the pathogenesis of heart failure. Cell Death Differ. 2018 03; 25(3):453-456. PMID: 29238072.
      Citations: 4     Fields:    Translation:Humans
    50. Kong P, Shinde AV, Su Y, Russo I, Chen B, Saxena A, Conway SJ, Graff JM, Frangogiannis NG. Opposing Actions of Fibroblast and Cardiomyocyte Smad3 Signaling in the Infarcted Myocardium. Circulation. 2018 02 13; 137(7):707-724. PMID: 29229611.
      Citations: 44     Fields:    Translation:AnimalsCells
    51. Frangogiannis NG. Fibroblasts and the extracellular matrix in right ventricular disease. Cardiovasc Res. 2017 Oct 01; 113(12):1453-1464. PMID: 28957531.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    52. Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B. Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 09 18; 8(1):578. PMID: 28924218.
      Citations: 11     Fields:    Translation:AnimalsCells
    53. Shinde AV, Dobaczewski M, de Haan JJ, Saxena A, Lee KK, Xia Y, Chen W, Su Y, Hanif W, Kaur Madahar I, Paulino VM, Melino G, Frangogiannis NG. Tissue transglutaminase induction in the pressure-overloaded myocardium regulates matrix remodelling. Cardiovasc Res. 2017 Jul 01; 113(8):892-905. PMID: 28371893.
      Citations: 11     Fields:    Translation:AnimalsCells
    54. Hanif W, Alex L, Su Y, Shinde AV, Russo I, Li N, Frangogiannis NG. Left atrial remodeling, hypertrophy, and fibrosis in mouse models of heart failure. Cardiovasc Pathol. 2017 Sep - Oct; 30:27-37. PMID: 28759817.
      Citations: 17     Fields:    Translation:HumansAnimals
    55. Frangogiannis NG. The extracellular matrix in myocardial injury, repair, and remodeling. J Clin Invest. 2017 May 01; 127(5):1600-1612. PMID: 28459429.
      Citations: 113     Fields:    Translation:HumansAnimalsCells
    56. Frangogiannis NG. Editor's Choice- Activation of the innate immune system in the pathogenesis of acute heart failure. Eur Heart J Acute Cardiovasc Care. 2018 Jun; 7(4):358-361. PMID: 28452231.
      Citations:    Fields:    Translation:Humans
    57. Shinde AV, Frangogiannis NG. Mechanisms of Fibroblast Activation in the Remodeling Myocardium. Curr Pathobiol Rep. 2017 Jun; 5(2):145-152. PMID: 29057165.
      Citations: 10     
    58. Frangogiannis NG. The role of transforming growth factor (TGF)-ß in the infarcted myocardium. J Thorac Dis. 2017 Mar; 9(Suppl 1):S52-S63. PMID: 28446968.
      Citations: 43     
    59. Chen B, Frangogiannis NG. Immune cells in repair of the infarcted myocardium. Microcirculation. 2017 01; 24(1). PMID: 27542099.
      Citations: 27     Fields:    Translation:HumansAnimals
    60. Shinde AV, Humeres C, Frangogiannis NG. The role of a-smooth muscle actin in fibroblast-mediated matrix contraction and remodeling. Biochim Biophys Acta Mol Basis Dis. 2017 01; 1863(1):298-309. PMID: 27825850.
      Citations: 76     Fields:    Translation:AnimalsCells
    61. Spinale FG, Frangogiannis NG, Hinz B, Holmes JW, Kassiri Z, Lindsey ML. Crossing Into the Next Frontier of Cardiac Extracellular Matrix Research. Circ Res. 2016 10 28; 119(10):1040-1045. PMID: 27789578.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    62. Frangogiannis NG. The Functional Pluralism of Fibroblasts in the Infarcted Myocardium. Circ Res. 2016 10 28; 119(10):1049-1051. PMID: 27789580.
      Citations: 10     Fields:    Translation:Cells
    63. Chen B, Frangogiannis NG. Macrophages in the Remodeling Failing Heart. Circ Res. 2016 09 16; 119(7):776-8. PMID: 27635078.
      Citations: 16     Fields:    Translation:Cells
    64. Frunza O, Russo I, Shinde AV, Su Y, Frangogiannis NG. Authors' Reply. Am J Pathol. 2016 Aug; 186(8):2234-2235. PMID: 27461365.
      Citations:    Fields:    
    65. Prabhu SD, Frangogiannis NG. The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis. Circ Res. 2016 06 24; 119(1):91-112. PMID: 27340270.
      Citations: 386     Fields:    Translation:HumansAnimalsCells
    66. Frunza O, Russo I, Saxena A, Shinde AV, Humeres C, Hanif W, Rai V, Su Y, Frangogiannis NG. Myocardial Galectin-3 Expression Is Associated with Remodeling of the Pressure-Overloaded Heart and May Delay the Hypertrophic Response without Affecting Survival, Dysfunction, and Cardiac Fibrosis. Am J Pathol. 2016 05; 186(5):1114-27. PMID: 26948424.
      Citations: 27     Fields:    Translation:AnimalsCells
    67. Frangogiannis NG. Fibroblast-Extracellular Matrix Interactions in Tissue Fibrosis. Curr Pathobiol Rep. 2016 Mar; 4(1):11-18. PMID: 27171595.
      Citations: 13     
    68. Russo I, Frangogiannis NG. Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities. J Mol Cell Cardiol. 2016 Jan; 90:84-93. PMID: 26705059.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    69. Saxena A, Shinde AV, Haque Z, Wu YJ, Chen W, Su Y, Frangogiannis NG. The role of Interleukin Receptor Associated Kinase (IRAK)-M in regulation of myofibroblast phenotype in vitro, and in an experimental model of non-reperfused myocardial infarction. J Mol Cell Cardiol. 2015 Dec; 89(Pt B):223-31. PMID: 26542797.
      Citations: 4     Fields:    Translation:AnimalsCells
    70. Frangogiannis NG. Pathophysiology of Myocardial Infarction. Compr Physiol. 2015 Sep 20; 5(4):1841-75. PMID: 26426469.
      Citations: 116     Fields:    Translation:HumansAnimalsCells
    71. Frangogiannis NG. Emerging roles for macrophages in cardiac injury: cytoprotection, repair, and regeneration. J Clin Invest. 2015 Aug 03; 125(8):2927-30. PMID: 26214519.
      Citations: 16     Fields:    Translation:AnimalsCells
    72. Saxena A, Russo I, Frangogiannis NG. Inflammation as a therapeutic target in myocardial infarction: learning from past failures to meet future challenges. Transl Res. 2016 Jan; 167(1):152-66. PMID: 26241027.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    73. Shinde AV, Frangogiannis NG. Mediators secreted by myeloid cells may protect and repair the infarcted myocardium. Circ Res. 2015 Jun 19; 117(1):10-2. PMID: 26089362.
      Citations:    Fields:    Translation:HumansAnimals
    74. Frangogiannis NG. The reparative function of cardiomyocytes in the infarcted myocardium. Cell Metab. 2015 Jun 02; 21(6):797-8. PMID: 26039445.
      Citations: 6     Fields:    Translation:AnimalsCells
    75. Biernacka A, Cavalera M, Wang J, Russo I, Shinde A, Kong P, Gonzalez-Quesada C, Rai V, Dobaczewski M, Lee DW, Wang XF, Frangogiannis NG. Smad3 Signaling Promotes Fibrosis While Preserving Cardiac and Aortic Geometry in Obese Diabetic Mice. Circ Heart Fail. 2015 Jul; 8(4):788-98. PMID: 25985794.
      Citations: 46     Fields:    Translation:AnimalsCells
    76. Frangogiannis NG. Inflammation in cardiac injury, repair and regeneration. Curr Opin Cardiol. 2015 May; 30(3):240-5. PMID: 25807226.
      Citations: 59     Fields:    Translation:HumansCells
    77. Frangogiannis NG. Interleukin-1 in cardiac injury, repair, and remodeling: pathophysiologic and translational concepts. Discoveries (Craiova). 2015 Jan-Mar; 3(1). PMID: 26273700.
      Citations: 25     
    78. Frangogiannis NG. Targeting the transforming growth factor (TGF)-ß cascade in the remodeling heart: benefits and perils. J Mol Cell Cardiol. 2014 Nov; 76:169-71. PMID: 25218305.
      Citations: 11     Fields:    Translation:HumansAnimals
    79. Saxena A, Dobaczewski M, Rai V, Haque Z, Chen W, Li N, Frangogiannis NG. Regulatory T cells are recruited in the infarcted mouse myocardium and may modulate fibroblast phenotype and function. Am J Physiol Heart Circ Physiol. 2014 Oct 15; 307(8):H1233-42. PMID: 25128167.
      Citations: 55     Fields:    Translation:AnimalsCells
    80. Saxena A, Bujak M, Frunza O, Dobaczewski M, Gonzalez-Quesada C, Lu B, Gerard C, Frangogiannis NG. CXCR3-independent actions of the CXC chemokine CXCL10 in the infarcted myocardium and in isolated cardiac fibroblasts are mediated through proteoglycans. Cardiovasc Res. 2014 Jul 15; 103(2):217-27. PMID: 24891401.
      Citations: 29     Fields:    Translation:AnimalsCells
    81. Cavalera M, Wang J, Frangogiannis NG. Obesity, metabolic dysfunction, and cardiac fibrosis: pathophysiological pathways, molecular mechanisms, and therapeutic opportunities. Transl Res. 2014 Oct; 164(4):323-35. PMID: 24880146.
      Citations: 79     Fields:    Translation:HumansAnimals
    82. Frangogiannis NG. The inflammatory response in myocardial injury, repair, and remodelling. Nat Rev Cardiol. 2014 May; 11(5):255-65. PMID: 24663091.
      Citations: 359     Fields:    Translation:HumansCells
    83. Frangogiannis NG. The immune system and the remodeling infarcted heart: cell biological insights and therapeutic opportunities. J Cardiovasc Pharmacol. 2014 Mar; 63(3):185-95. PMID: 24072174.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    84. Rienks M, Papageorgiou AP, Frangogiannis NG, Heymans S. Myocardial extracellular matrix: an ever-changing and diverse entity. Circ Res. 2014 Feb 28; 114(5):872-88. PMID: 24577967.
      Citations: 94     Fields:    Translation:HumansAnimalsCells
    85. Frangogiannis NG. Contribution of extramedullary organs in myocardial inflammation and remodeling: does the spleen cause cardiac melancholy? Circ Res. 2014 Jan 17; 114(2):230-2. PMID: 24436423.
      Citations:    Fields:    Translation:AnimalsCells
    86. Cavalera M, Frangogiannis NG. Targeting the chemokines in cardiac repair. Curr Pharm Des. 2014; 20(12):1971-9. PMID: 23844733.
      Citations: 16     Fields:    Translation:HumansAnimals
    87. Shinde AV, Frangogiannis NG. Fibroblasts in myocardial infarction: a role in inflammation and repair. J Mol Cell Cardiol. 2014 May; 70:74-82. PMID: 24321195.
      Citations: 166     Fields:    Translation:HumansAnimalsCells
    88. Frangogiannis NG. MicroRNAs and endothelial function: many challenges and early hopes for clinical applications. J Am Coll Cardiol. 2014 Apr 29; 63(16):1695-6. PMID: 24291271.
      Citations: 1     Fields:    Translation:HumansAnimals
    89. Kong P, Cavalera M, Frangogiannis NG. The role of thrombospondin (TSP)-1 in obesity and diabetes. Adipocyte. 2014 Jan 01; 3(1):81-4. PMID: 24575376.
      Citations: 15     Fields:    
    90. Gonzalez-Quesada C, Cavalera M, Biernacka A, Kong P, Lee DW, Saxena A, Frunza O, Dobaczewski M, Shinde A, Frangogiannis NG. Thrombospondin-1 induction in the diabetic myocardium stabilizes the cardiac matrix in addition to promoting vascular rarefaction through angiopoietin-2 upregulation. Circ Res. 2013 Dec 06; 113(12):1331-44. PMID: 24081879.
      Citations: 58     Fields:    Translation:AnimalsCells
    91. Saxena A, Chen W, Su Y, Rai V, Uche OU, Li N, Frangogiannis NG. IL-1 induces proinflammatory leukocyte infiltration and regulates fibroblast phenotype in the infarcted myocardium. J Immunol. 2013 Nov 01; 191(9):4838-48. PMID: 24078695.
      Citations: 85     Fields:    Translation:Animals
    92. Kong P, Christia P, Saxena A, Su Y, Frangogiannis NG. Lack of specificity of fibroblast-specific protein 1 in cardiac remodeling and fibrosis. Am J Physiol Heart Circ Physiol. 2013 Nov 01; 305(9):H1363-72. PMID: 23997102.
      Citations: 89     Fields:    Translation:AnimalsCells
    93. Christia P, Frangogiannis NG. Targeting inflammatory pathways in myocardial infarction. Eur J Clin Invest. 2013 Sep; 43(9):986-95. PMID: 23772948.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    94. Kong P, Gonzalez-Quesada C, Li N, Cavalera M, Lee DW, Frangogiannis NG. Thrombospondin-1 regulates adiposity and metabolic dysfunction in diet-induced obesity enhancing adipose inflammation and stimulating adipocyte proliferation. Am J Physiol Endocrinol Metab. 2013 Aug 01; 305(3):E439-50. PMID: 23757408.
      Citations: 41     Fields:    Translation:AnimalsCells
    95. Christia P, Bujak M, Gonzalez-Quesada C, Chen W, Dobaczewski M, Reddy A, Frangogiannis NG. Systematic characterization of myocardial inflammation, repair, and remodeling in a mouse model of reperfused myocardial infarction. J Histochem Cytochem. 2013 Aug; 61(8):555-70. PMID: 23714783.
      Citations: 43     Fields:    Translation:Animals
    96. Kong P, Christia P, Frangogiannis NG. The pathogenesis of cardiac fibrosis. Cell Mol Life Sci. 2014 Feb; 71(4):549-74. PMID: 23649149.
      Citations: 377     Fields:    Translation:HumansAnimalsCells
    97. Chen W, Saxena A, Li N, Sun J, Gupta A, Lee DW, Tian Q, Dobaczewski M, Frangogiannis NG. Endogenous IRAK-M attenuates postinfarction remodeling through effects on macrophages and fibroblasts. Arterioscler Thromb Vasc Biol. 2012 Nov; 32(11):2598-608. PMID: 22995519.
      Citations: 33     Fields:    Translation:AnimalsCells
    98. Chen W, Frangogiannis NG. Fibroblasts in post-infarction inflammation and cardiac repair. Biochim Biophys Acta. 2013 Apr; 1833(4):945-53. PMID: 22982064.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    99. Dobaczewski M, de Haan JJ, Frangogiannis NG. The extracellular matrix modulates fibroblast phenotype and function in the infarcted myocardium. J Cardiovasc Transl Res. 2012 Dec; 5(6):837-47. PMID: 22956156.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    100. Frangogiannis NG. Monomeric C-reactive protein and inflammatory injury in myocardial infarction. Cardiovasc Res. 2012 Oct 01; 96(1):4-6. PMID: 22871589.
      Citations: 2     Fields:    Translation:HumansCells
    101. Frangogiannis NG. Matricellular proteins in cardiac adaptation and disease. Physiol Rev. 2012 Apr; 92(2):635-88. PMID: 22535894.
      Citations: 163     Fields:    Translation:HumansAnimals
    102. Frangogiannis NG. Biomarkers: hopes and challenges in the path from discovery to clinical practice. Transl Res. 2012 Apr; 159(4):197-204. PMID: 22424424.
      Citations: 22     Fields:    Translation:Humans
    103. Frangogiannis NG. Regulation of the inflammatory response in cardiac repair. Circ Res. 2012 Jan 06; 110(1):159-73. PMID: 22223212.
      Citations: 365     Fields:    Translation:HumansAnimalsCells
    104. Frangogiannis NG. The stromal cell-derived factor-1/CXCR4 axis in cardiac injury and repair. J Am Coll Cardiol. 2011 Nov 29; 58(23):2424-6. PMID: 22115650.
      Citations: 12     Fields:    Translation:Animals
    105. Xia Y, Dobaczewski M, Gonzalez-Quesada C, Chen W, Biernacka A, Li N, Lee DW, Frangogiannis NG. Endogenous thrombospondin 1 protects the pressure-overloaded myocardium by modulating fibroblast phenotype and matrix metabolism. Hypertension. 2011 Nov; 58(5):902-11. PMID: 21947471.
      Citations: 64     Fields:    Translation:AnimalsCells
    106. Biernacka A, Dobaczewski M, Frangogiannis NG. TGF-ß signaling in fibrosis. Growth Factors. 2011 Oct; 29(5):196-202. PMID: 21740331.
      Citations: 328     Fields:    Translation:HumansAnimalsCells
    107. Biernacka A, Frangogiannis NG. Aging and Cardiac Fibrosis. Aging Dis. 2011 Apr; 2(2):158-173. PMID: 21837283.
      Citations: 164     
    108. Frangogiannis NG. Stromal cell-derived factor-1-mediated angiogenesis for peripheral arterial disease: ready for prime time? Circulation. 2011 Mar 29; 123(12):1267-9. PMID: 21403099.
      Citations: 4     Fields:    Translation:HumansAnimals
    109. Dobaczewski M, Frangogiannis NG. The cellular specificity of leptin-mediated actions in the infarcted heart. Cardiovasc Res. 2011 Jan 01; 89(1):9-11. PMID: 21062917.
      Citations: 2     Fields:    Translation:AnimalsCells
    110. Dobaczewski M, Chen W, Frangogiannis NG. Transforming growth factor (TGF)-ß signaling in cardiac remodeling. J Mol Cell Cardiol. 2011 Oct; 51(4):600-6. PMID: 21059352.
      Citations: 306     Fields:    Translation:HumansAnimalsCells
    111. Chen W, Frangogiannis NG. The role of inflammatory and fibrogenic pathways in heart failure associated with aging. Heart Fail Rev. 2010 Sep; 15(5):415-22. PMID: 20213186.
      Citations: 54     Fields:    Translation:HumansCells
    112. Dobaczewski M, Bujak M, Li N, Gonzalez-Quesada C, Mendoza LH, Wang XF, Frangogiannis NG. Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction. Circ Res. 2010 Aug 06; 107(3):418-28. PMID: 20522804.
      Citations: 149     Fields:    Translation:AnimalsCells
    113. Dobaczewski M, Xia Y, Bujak M, Gonzalez-Quesada C, Frangogiannis NG. CCR5 signaling suppresses inflammation and reduces adverse remodeling of the infarcted heart, mediating recruitment of regulatory T cells. Am J Pathol. 2010 May; 176(5):2177-87. PMID: 20382703.
      Citations: 116     Fields:    Translation:AnimalsCells
    114. Frangogiannis NG. Syndecan-1: a critical mediator in cardiac fibrosis. Hypertension. 2010 Feb; 55(2):233-5. PMID: 20048190.
      Citations: 12     Fields:    Translation:AnimalsCells
    115. Durgan DJ, Pulinilkunnil T, Villegas-Montoya C, Garvey ME, Frangogiannis NG, Michael LH, Chow CW, Dyck JR, Young ME. Short communication: ischemia/reperfusion tolerance is time-of-day-dependent: mediation by the cardiomyocyte circadian clock. Circ Res. 2010 Feb 19; 106(3):546-50. PMID: 20007913.
      Citations: 91     Fields:    Translation:AnimalsCells
    116. Bujak M, Dobaczewski M, Gonzalez-Quesada C, Xia Y, Leucker T, Zymek P, Veeranna V, Tager AM, Luster AD, Frangogiannis NG. Induction of the CXC chemokine interferon-gamma-inducible protein 10 regulates the reparative response following myocardial infarction. Circ Res. 2009 Nov 06; 105(10):973-83. PMID: 19797174.
      Citations: 69     Fields:    Translation:AnimalsCells
    117. Dobaczewski M, Gonzalez-Quesada C, Frangogiannis NG. The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction. J Mol Cell Cardiol. 2010 Mar; 48(3):504-11. PMID: 19631653.
      Citations: 200     Fields:    Translation:HumansAnimalsCells
    118. Dobaczewski M, Frangogiannis NG. Chemokines and cardiac fibrosis. Front Biosci (Schol Ed). 2009 Jun 01; 1:391-405. PMID: 19482709.
      Citations: 41     Fields:    Translation:HumansCells
    119. Bujak M, Frangogiannis NG. The role of IL-1 in the pathogenesis of heart disease. Arch Immunol Ther Exp (Warsz). 2009 May-Jun; 57(3):165-76. PMID: 19479203.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    120. Gonzalez-Quesada C, Frangogiannis NG. Monocyte chemoattractant protein-1/CCL2 as a biomarker in acute coronary syndromes. Curr Atheroscler Rep. 2009 Mar; 11(2):131-8. PMID: 19228487.
      Citations: 25     Fields:    Translation:Humans
    121. Xia Y, Lee K, Li N, Corbett D, Mendoza L, Frangogiannis NG. Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload. Histochem Cell Biol. 2009 Apr; 131(4):471-81. PMID: 19030868.
      Citations: 100     Fields:    Translation:AnimalsCells
    122. Thakker GD, Frangogiannis NG, Zymek PT, Sharma S, Raya JL, Barger PM, Taegtmeyer H, Entman ML, Ballantyne CM. Increased myocardial susceptibility to repetitive ischemia with high-fat diet-induced obesity. Obesity (Silver Spring). 2008 Dec; 16(12):2593-600. PMID: 18833212.
      Citations: 14     Fields:    Translation:Animals
    123. Dobaczewski M, Frangogiannis NG. Chemokines in myocardial infarction: translating basic research into clinical medicine. Future Cardiol. 2008 Jul; 4(4):347-51. PMID: 19804314.
      Citations: 5     Fields:    
    124. Frangogiannis NG. The immune system and cardiac repair. Pharmacol Res. 2008 Aug; 58(2):88-111. PMID: 18620057.
      Citations: 229     Fields:    Translation:HumansAnimalsCells
    125. Bujak M, Dobaczewski M, Chatila K, Mendoza LH, Li N, Reddy A, Frangogiannis NG. Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling. Am J Pathol. 2008 Jul; 173(1):57-67. PMID: 18535174.
      Citations: 115     Fields:    Translation:AnimalsCells
    126. Bujak M, Kweon HJ, Chatila K, Li N, Taffet G, Frangogiannis NG. Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction. J Am Coll Cardiol. 2008 Apr 08; 51(14):1384-92. PMID: 18387441.
      Citations: 80     Fields:    Translation:AnimalsCells
    127. Huebener P, Abou-Khamis T, Zymek P, Bujak M, Ying X, Chatila K, Haudek S, Thakker G, Frangogiannis NG. CD44 is critically involved in infarct healing by regulating the inflammatory and fibrotic response. J Immunol. 2008 Feb 15; 180(4):2625-33. PMID: 18250474.
      Citations: 76     Fields:    Translation:AnimalsCells
    128. Rao L, Ling Y, He R, Gilbert AL, Frangogiannis NG, Wang J, Nagueh SF, Khoury DS. Integrated multimodal-catheter imaging unveils principal relationships among ventricular electrical activity, anatomy, and function. Am J Physiol Heart Circ Physiol. 2008 Feb; 294(2):H1002-9. PMID: 18083892.
      Citations: 1     Translation:Animals
    129. Frangogiannis NG. The prognostic value of monocyte chemoattractant protein-1/CCL2 in acute coronary syndromes. J Am Coll Cardiol. 2007 Nov 27; 50(22):2125-7. PMID: 18036448.
      Citations: 10     Fields:    Translation:HumansAnimals
    130. Bujak M, Ren G, Kweon HJ, Dobaczewski M, Reddy A, Taffet G, Wang XF, Frangogiannis NG. Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling. Circulation. 2007 Nov 06; 116(19):2127-38. PMID: 17967775.
      Citations: 156     Fields:    Translation:AnimalsCells
    131. Xia Y, Frangogiannis NG. MCP-1/CCL2 as a therapeutic target in myocardial infarction and ischemic cardiomyopathy. Inflamm Allergy Drug Targets. 2007 Jun; 6(2):101-7. PMID: 17692033.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    132. Frangogiannis NG. Chemokines in ischemia and reperfusion. Thromb Haemost. 2007 May; 97(5):738-47. PMID: 17479184.
      Citations: 95     Fields:    Translation:HumansAnimalsCells
    133. Frangogiannis NG, Dewald O, Xia Y, Ren G, Haudek S, Leucker T, Kraemer D, Taffet G, Rollins BJ, Entman ML. Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy. Circulation. 2007 Feb 06; 115(5):584-92. PMID: 17283277.
      Citations: 113     Fields:    Translation:AnimalsCells
    134. Chatila K, Ren G, Xia Y, Huebener P, Bujak M, Frangogiannis NG. The role of the thrombospondins in healing myocardial infarcts. Cardiovasc Hematol Agents Med Chem. 2007 Jan; 5(1):21-7. PMID: 17266545.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    135. Zymek P, Nah DY, Bujak M, Ren G, Koerting A, Leucker T, Huebener P, Taffet G, Entman M, Frangogiannis NG. Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling. Cardiovasc Res. 2007 May 01; 74(2):313-22. PMID: 17188669.
      Citations: 29     Fields:    Translation:AnimalsCells
    136. Haudek SB, Xia Y, Huebener P, Lee JM, Carlson S, Crawford JR, Pilling D, Gomer RH, Trial J, Frangogiannis NG, Entman ML. Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice. Proc Natl Acad Sci U S A. 2006 Nov 28; 103(48):18284-9. PMID: 17114286.
      Citations: 174     Fields:    Translation:AnimalsCells
    137. Zymek P, Bujak M, Chatila K, Cieslak A, Thakker G, Entman ML, Frangogiannis NG. The role of platelet-derived growth factor signaling in healing myocardial infarcts. J Am Coll Cardiol. 2006 Dec 05; 48(11):2315-23. PMID: 17161265.
      Citations: 79     Fields:    Translation:AnimalsCells
    138. Frangogiannis NG. The mechanistic basis of infarct healing. Antioxid Redox Signal. 2006 Nov-Dec; 8(11-12):1907-39. PMID: 17034340.
      Citations: 99     Fields:    Translation:HumansAnimals
    139. Bujak M, Frangogiannis NG. The role of TGF-beta signaling in myocardial infarction and cardiac remodeling. Cardiovasc Res. 2007 May 01; 74(2):184-95. PMID: 17109837.
      Citations: 344     Fields:    Translation:HumansAnimalsCells
    140. Thakker GD, Frangogiannis NG, Bujak M, Zymek P, Gaubatz JW, Reddy AK, Taffet G, Michael LH, Entman ML, Ballantyne CM. Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction. Am J Physiol Heart Circ Physiol. 2006 Nov; 291(5):H2504-14. PMID: 16731644.
      Citations: 45     Translation:Animals
    141. Frangogiannis NG, Entman ML. Identification of mast cells in the cellular response to myocardial infarction. Methods Mol Biol. 2006; 315:91-101. PMID: 16110151.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    142. Frangogiannis NG. Targeting the inflammatory response in healing myocardial infarcts. Curr Med Chem. 2006; 13(16):1877-93. PMID: 16842199.
      Citations: 81     Fields:    Translation:HumansCells
    143. Park TH, Nagueh SF, Khoury DS, Kopelen HA, Akrivakis S, Nasser K, Ren G, Frangogiannis NG. Impact of myocardial structure and function postinfarction on diastolic strain measurements: implications for assessment of myocardial viability. Am J Physiol Heart Circ Physiol. 2006 Feb; 290(2):H724-31. PMID: 16183729.
      Citations: 26     Translation:Animals
    144. Frangogiannis NG, Entman ML. Chemokines in myocardial ischemia. Trends Cardiovasc Med. 2005 Jul; 15(5):163-9. PMID: 16165012.
      Citations: 42     Fields:    Translation:HumansAnimals
    145. Frangogiannis NG, Ren G, Dewald O, Zymek P, Haudek S, Koerting A, Winkelmann K, Michael LH, Lawler J, Entman ML. Critical role of endogenous thrombospondin-1 in preventing expansion of healing myocardial infarcts. Circulation. 2005 Jun 07; 111(22):2935-42. PMID: 15927970.
      Citations: 131     Fields:    Translation:AnimalsCells
    146. Dewald O, Zymek P, Winkelmann K, Koerting A, Ren G, Abou-Khamis T, Michael LH, Rollins BJ, Entman ML, Frangogiannis NG. CCL2/Monocyte Chemoattractant Protein-1 regulates inflammatory responses critical to healing myocardial infarcts. Circ Res. 2005 Apr 29; 96(8):881-9. PMID: 15774854.
      Citations: 249     Fields:    Translation:AnimalsCells
    147. Somasundaram P, Ren G, Nagar H, Kraemer D, Mendoza L, Michael LH, Caughey GH, Entman ML, Frangogiannis NG. Mast cell tryptase may modulate endothelial cell phenotype in healing myocardial infarcts. J Pathol. 2005 Jan; 205(1):102-11. PMID: 15586361.
      Citations: 33     Fields:    Translation:AnimalsCells
    148. Frangogiannis NG, Entman ML. Targeting the chemokines in myocardial inflammation. Circulation. 2004 Sep 14; 110(11):1341-2. PMID: 15364818.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    149. Dobaczewski M, Akrivakis S, Nasser K, Michael LH, Entman ML, Frangogiannis NG. Vascular mural cells in healing canine myocardial infarcts. J Histochem Cytochem. 2004 Aug; 52(8):1019-29. PMID: 15258177.
      Citations: 16     Fields:    Translation:Animals
    150. Frangogiannis NG. The role of the chemokines in myocardial ischemia and reperfusion. Curr Vasc Pharmacol. 2004 Apr; 2(2):163-74. PMID: 15320517.
      Citations: 16     Fields:    Translation:HumansAnimals
    151. Dewald O, Ren G, Duerr GD, Zoerlein M, Klemm C, Gersch C, Tincey S, Michael LH, Entman ML, Frangogiannis NG. Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction. Am J Pathol. 2004 Feb; 164(2):665-77. PMID: 14742270.
      Citations: 145     Fields:    Translation:AnimalsCells
    152. Ren G, Dewald O, Frangogiannis NG. Inflammatory mechanisms in myocardial infarction. Curr Drug Targets Inflamm Allergy. 2003 Sep; 2(3):242-56. PMID: 14561159.
      Citations: 53     Fields:    Translation:HumansAnimals
    153. Frangogiannis NG, Mendoza LH, Ren G, Akrivakis S, Jackson PL, Michael LH, Smith CW, Entman ML. MCSF expression is induced in healing myocardial infarcts and may regulate monocyte and endothelial cell phenotype. Am J Physiol Heart Circ Physiol. 2003 Aug; 285(2):H483-92. PMID: 12689859.
      Citations: 40     Translation:AnimalsCells
    154. Dewald O, Frangogiannis NG, Zoerlein M, Duerr GD, Klemm C, Knuefermann P, Taffet G, Michael LH, Crapo JD, Welz A, Entman ML. Development of murine ischemic cardiomyopathy is associated with a transient inflammatory reaction and depends on reactive oxygen species. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2700-5. PMID: 12586861.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    155. Shimoni S, Frangogiannis NG, Aggeli CJ, Shan K, Verani MS, Quinones MA, Espada R, Letsou GV, Lawrie GM, Winters WL, Reardon MJ, Zoghbi WA. Identification of hibernating myocardium with quantitative intravenous myocardial contrast echocardiography: comparison with dobutamine echocardiography and thallium-201 scintigraphy. Circulation. 2003 Feb 04; 107(4):538-44. PMID: 12566363.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    156. Fernandes LS, Conde ID, Wayne Smith C, Kansas GS, Snapp KR, Bennet N, Ballantyne C, McIntire LV, O'Brian Smith E, Klem JA, Mathew S, Frangogiannis N, Turner NA, Maresh KJ, Kleiman NS. Platelet-monocyte complex formation: effect of blocking PSGL-1 alone, and in combination with alphaIIbbeta3 and alphaMbeta2, in coronary stenting. Thromb Res. 2003; 111(3):171-7. PMID: 14678816.
      Citations: 12     Fields:    Translation:HumansCells
    157. Shimoni S, Frangogiannis NG, Aggeli CJ, Shan K, Quinones MA, Espada R, Letsou GV, Lawrie GM, Winters WL, Reardon MJ, Zoghbi WA. Microvascular structural correlates of myocardial contrast echocardiography in patients with coronary artery disease and left ventricular dysfunction: implications for the assessment of myocardial hibernation. Circulation. 2002 Aug 20; 106(8):950-6. PMID: 12186799.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    158. Gersch C, Dewald O, Zoerlein M, Michael LH, Entman ML, Frangogiannis NG. Mast cells and macrophages in normal C57/BL/6 mice. Histochem Cell Biol. 2002 Jul; 118(1):41-9. PMID: 12122446.
      Citations: 43     Fields:    Translation:AnimalsCells
    159. Frangogiannis NG, Shimoni S, Chang SM, Ren G, Dewald O, Gersch C, Shan K, Aggeli C, Reardon M, Letsou GV, Espada R, Ramchandani M, Entman ML, Zoghbi WA. Active interstitial remodeling: an important process in the hibernating human myocardium. J Am Coll Cardiol. 2002 May 01; 39(9):1468-74. PMID: 11985909.
      Citations: 29     Fields:    Translation:HumansCells
    160. Frangogiannis NG, Shimoni S, Chang SM, Ren G, Shan K, Aggeli C, Reardon MJ, Letsou GV, Espada R, Ramchandani M, Entman ML, Zoghbi WA. Evidence for an active inflammatory process in the hibernating human myocardium. Am J Pathol. 2002 Apr; 160(4):1425-33. PMID: 11943726.
      Citations: 26     Fields:    Translation:HumansCells
    161. Frangogiannis NG, Smith CW, Entman ML. The inflammatory response in myocardial infarction. Cardiovasc Res. 2002 Jan; 53(1):31-47. PMID: 11744011.
      Citations: 542     Fields:    Translation:HumansCells
    162. Ren G, Michael LH, Entman ML, Frangogiannis NG. Morphological characteristics of the microvasculature in healing myocardial infarcts. J Histochem Cytochem. 2002 Jan; 50(1):71-9. PMID: 11748296.
      Citations: 57     Fields:    Translation:AnimalsCells
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