MINGSHAN XUE

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Neuroscience
Address1250 MOURSUND STREET
Houston, TX 77030
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    R01NS100893     (XUE, MINGSHAN)Feb 1, 2017 - Jan 31, 2022
    NIH/NINDS
    Synaptic Dysfunction of Neural Circuits in Neurodevelopmental Disorders
    Role: Principal Investigator

    R01MH117089     (XUE, MINGSHAN)Aug 16, 2018 - May 31, 2023
    NIH/NIMH
    Activity-Dependent Mechanisms Regulating Synaptic Excitation and Inhibition in Neural Circuits
    Role: Principal Investigator

    U01NS118288     (XUE, MINGSHAN)Aug 15, 2020 - May 31, 2024
    NIH/NINDS
    Molecular Engineering of Natural Light-Gated Chloride Channels for Optogenetic Inhibition
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chen W, Cai ZL, Chao ES, Chen H, Longley CM, Hao S, Chao HT, Kim JH, Messier JE, Zoghbi HY, Tang J, Swann JW, Xue M. Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy. Elife. 2020 Feb 19; 9. PMID: 32073399.
      Citations:    Fields:    
    2. Meng X, McGraw CM, Wang W, Jing J, Yeh SY, Wang L, Lopez J, Brown AM, Lin T, Chen W, Xue M, Sillitoe RV, Jiang X, Zoghbi HY. Neurexophilin4 is a selectively expressed a-neurexin ligand that modulates specific cerebellar synapses and motor functions. Elife. 2019 09 16; 8. PMID: 31524598.
      Citations: 1     Fields:    Translation:AnimalsCells
    3. Messier JE, Chen H, Cai ZL, Xue M. Targeting light-gated chloride channels to neuronal somatodendritic domain reduces their excitatory effect in the axon. Elife. 2018 08 09; 7. PMID: 30091701.
      Citations: 6     Fields:    Translation:AnimalsCells
    4. Yin J, Chen W, Chao ES, Soriano S, Wang L, Wang W, Cummock SE, Tao H, Pang K, Liu Z, Pereira FA, Samaco RC, Zoghbi HY, Xue M, Schaaf CP. Otud7a Knockout Mice Recapitulate Many Neurological Features of 15q13.3 Microdeletion Syndrome. Am J Hum Genet. 2018 02 01; 102(2):296-308. PMID: 29395075.
      Citations: 6     Fields:    Translation:AnimalsCells
    5. Jiang X, Chen J, Bajic A, Zhang C, Song X, Carroll SL, Cai ZL, Tang M, Xue M, Cheng N, Schaaf CP, Li F, MacKenzie KR, Ferreon ACM, Xia F, Wang MC, Maletic-Savatic M, Wang J. Quantitative real-time imaging of glutathione. Nat Commun. 2017 07 13; 8:16087. PMID: 28703127.
      Citations: 23     Fields:    Translation:HumansCells
    6. Yeh SY, Huang WH, Wang W, Ward CS, Chao ES, Wu Z, Tang B, Tang J, Sun JJ, Esther van der Heijden M, Gray PA, Xue M, Ray RS, Ren D, Zoghbi HY. Respiratory Network Stability and Modulatory Response to Substance P Require Nalcn. Neuron. 2017 Apr 19; 94(2):294-303.e4. PMID: 28392070.
      Citations: 14     Fields:    Translation:AnimalsCells
    7. Yin J, Chen W, Yang H, Xue M, Schaaf CP. Chrna7 deficient mice manifest no consistent neuropsychiatric and behavioral phenotypes. Sci Rep. 2017 01 03; 7:39941. PMID: 28045139.
      Citations: 7     Fields:    Translation:Animals
    8. Meng X, Wang W, Lu H, He LJ, Chen W, Chao ES, Fiorotto ML, Tang B, Herrera JA, Seymour ML, Neul JL, Pereira FA, Tang J, Xue M, Zoghbi HY. Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders. Elife. 2016 06 21; 5. PMID: 27328325.
      Citations: 21     Fields:    Translation:AnimalsCells
    9. Xue M, Atallah BV, Scanziani M. Equalizing excitation-inhibition ratios across visual cortical neurons. Nature. 2014 Jul 31; 511(7511):596-600. PMID: 25043046.
      Citations: 171     Fields:    Translation:HumansAnimalsCells
    10. Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY. Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature. 2010 Nov 11; 468(7321):263-9. PMID: 21068835.
      Citations: 426     Fields:    Translation:AnimalsCells
    11. Xue M, Craig TK, Shin OH, Li L, Brautigam CA, Tomchick DR, Südhof TC, Rosenmund C, Rizo J. Structural and mutational analysis of functional differentiation between synaptotagmins-1 and -7. PLoS One. 2010 Sep 02; 5(9). PMID: 20824061.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    12. Xue M, Craig TK, Xu J, Chao HT, Rizo J, Rosenmund C. Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity. Nat Struct Mol Biol. 2010 May; 17(5):568-75. PMID: 20400951.
      Citations: 57     Fields:    Translation:AnimalsCells
    13. Xue M, Lin YQ, Pan H, Reim K, Deng H, Bellen HJ, Rosenmund C. Tilting the balance between facilitatory and inhibitory functions of mammalian and Drosophila Complexins orchestrates synaptic vesicle exocytosis. Neuron. 2009 Nov 12; 64(3):367-80. PMID: 19914185.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    14. Xue M, Rosenmund C. The headache of a hyperactive calcium channel. Neuron. 2009 Mar 12; 61(5):653-4. PMID: 19285460.
      Citations: 2     Fields:    Translation:Animals
    15. Xue M, Ma C, Craig TK, Rosenmund C, Rizo J. The Janus-faced nature of the C(2)B domain is fundamental for synaptotagmin-1 function. Nat Struct Mol Biol. 2008 Nov; 15(11):1160-8. PMID: 18953334.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    16. Xue M, Stradomska A, Chen H, Brose N, Zhang W, Rosenmund C, Reim K. Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system. Proc Natl Acad Sci U S A. 2008 Jun 03; 105(22):7875-80. PMID: 18505837.
      Citations: 55     Fields:    Translation:AnimalsCells
    17. Xue M, Reim K, Chen X, Chao HT, Deng H, Rizo J, Brose N, Rosenmund C. Distinct domains of complexin I differentially regulate neurotransmitter release. Nat Struct Mol Biol. 2007 Oct; 14(10):949-58. PMID: 17828276.
      Citations: 94     Fields:    Translation:AnimalsCells
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