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MICHAEL A MANCINI

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
DivisionMolecular & Cellular Biology
AddressOne Baylor Plaza
MS BCM 130
Houston TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pharmacology and Chemical Biology
    DivisionPharmacology


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    Collapse keywords
    microscopy, estrogen receptor, androgen receptor, high content analysis, high content screening, monoclonal antibodies, hybridomas, image analysis, drug screening, endocrine disrupting chemicals


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Szafran AT, Stossi F, Mancini MG, Walker CL, Mancini MA. Characterizing properties of non-estrogenic substituted bisphenol analogs using high throughput microscopy and image analysis. PLoS One. 2017; 12(7):e0180141. PMID: 28704378.
      View in: PubMed
    2. Wang H, Tian L, Goldstein A, Liu J, Lo HC, Sheng K, Welte T, Wong STC, Gugala Z, Stossi F, Zong C, Li Z, Mancini MA, Zhang XH. Bone-in-culture array as a platform to model early-stage bone metastases and discover anti-metastasis therapies. Nat Commun. 2017 Apr 21; 8:15045. PMID: 28429794.
      View in: PubMed
    3. Tian L, Goldstein A, Wang H, Ching Lo H, Sun Kim I, Welte T, Sheng K, Dobrolecki LE, Zhang X, Putluri N, Phung TL, Mani SA, Stossi F, Sreekumar A, Mancini MA, Decker WK, Zong C, Lewis MT, Zhang XH. Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming. Nature. 2017 Apr 03. PMID: 28371798.
      View in: PubMed
    4. Aagaard KM, Lahon A, Suter MA, Arya RP, Seferovic MD, Vogt MB, Hu M, Stossi F, Mancini MA, Harris RA, Kahr M, Eppes C, Rac M, Belfort MA, Park CS, Lacorazza D, Rico-Hesse R. Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. Sci Rep. 2017 Jan 27; 7:41389. PMID: 28128342.
      View in: PubMed
    5. Szafran AT, Stephan C, Bolt M, Mancini MG, Marcelli M, Mancini MA. High-Content Screening Identifies Src Family Kinases as Potential Regulators of AR-V7 Expression and Androgen-Independent Cell Growth. Prostate. 2016 Oct 4. PMID: 27699828.
      View in: PubMed
    6. Xiao L, Lanz RB, Frolov A, Castro PD, Zhang Z, Dong B, Xue W, Jung SY, Lydon JP, Edwards DP, Mancini MA, Feng Q, Ittmann MM, He B. The germ cell gene TDRD1 as an ERG target gene and a novel prostate cancer biomarker. Prostate. 2016 Jun 8. PMID: 27272765.
      View in: PubMed
    7. Kaushik AK, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, Zaslavsky A, Putluri V, Vasu VT, Zhang Y, Khan AS, Lloyd S, Szafran AT, Dasgupta S, Bader DA, Stossi F, Li H, Samanta S, Cao X, Tsouko E, Huang S, Frigo DE, Chan L, Edwards DP, Kaipparettu BA, Mitsiades N, Weigel NL, Mancini M, McGuire SE, Mehra R, Ittmann MM, Chinnaiyan AM, Putluri N, Palapattu GS, Michailidis G, Sreekumar A. Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer. Nat Commun. 2016; 7:11612. PMID: 27194471; PMCID: PMC4874037.
    8. Stossi F, Dandekar RD, Bolt MJ, Newberg JY, Mancini MG, Kaushik AK, Putluri V, Sreekumar A, Mancini MA. High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator. Oncotarget. 2016 Mar 29; 7(13):16962-74. PMID: 26918604.
      View in: PubMed
    9. Sun H, Mediwala SN, Szafran AT, Mancini MA, Marcelli M. CUDC-101, a Novel Inhibitor of Full-Length Androgen Receptor (flAR) and Androgen Receptor Variant 7 (AR-V7) Activity: Mechanism of Action and In Vivo Efficacy. Horm Cancer. 2016 Jun; 7(3):196-210. PMID: 26957440; PMCID: PMC4896833 [Available on 06/01/17].
    10. Treviño LS, Bolt MJ, Grimm SL, Edwards DP, Mancini MA, Weigel NL. Differential Regulation of Progesterone Receptor-Mediated Transcription by CDK2 and DNA-PK. Mol Endocrinol. 2016 Feb; 30(2):158-72. PMID: 26652902; PMCID: PMC4792227 [Available on 02/01/17].
    11. Szafran AT, Mancini MG, Nickerson JA, Edwards DP, Mancini MA. Use of HCA in subproteome-immunization and screening of hybridoma supernatants to define distinct antibody binding patterns. Methods. 2016 Mar 1; 96:75-84. PMID: 26521976; PMCID: PMC4891975.
    12. Wang L, Yu Y, Chow DC, Yan F, Hsu CC, Stossi F, Mancini MA, Palzkill T, Liao L, Zhou S, Xu J, Lonard DM, O'Malley BW. Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10; 28(2):240-52. PMID: 26267537.
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    13. Hartig SM, Bader DA, Abadie KV, Motamed M, Hamilton MP, Long W, York B, Mueller M, Wagner M, Trauner M, Chan L, Bajaj M, Moore DD, Mancini MA, McGuire SE. Ubc9 Impairs Activation of the Brown Fat Energy Metabolism Program in Human White Adipocytes. Mol Endocrinol. 2015 Sep; 29(9):1320-33. PMID: 26192107.
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    14. Large MJ, Wetendorf M, Lanz RB, Hartig SM, Creighton CJ, Mancini MA, Kovanci E, Lee KF, Threadgill DW, Lydon JP, Jeong JW, DeMayo FJ. The epidermal growth factor receptor critically regulates endometrial function during early pregnancy. PLoS Genet. 2014 Jun; 10(6):e1004451. PMID: 24945252; PMCID: PMC4063709.
    15. Stossi F, Bolt MJ, Ashcroft FJ, Lamerdin JE, Melnick JS, Powell RT, Dandekar RD, Mancini MG, Walker CL, Westwick JK, Mancini MA. Defining estrogenic mechanisms of bisphenol A analogs through high throughput microscopy-based contextual assays. Chem Biol. 2014 Jun 19; 21(6):743-53. PMID: 24856822; PMCID: PMC4301571.
    16. Lee J, Tiwari A, Shum V, Mills GB, Mancini MA, Igoshin OA, Balázsi G. Unraveling the regulatory connections between two controllers of breast cancer cell fate. Nucleic Acids Res. 2014 Jun; 42(11):6839-49. PMID: 24792166; PMCID: PMC4066784.
    17. Bharadwaj U, Eckols TK, Kolosov M, Kasembeli MM, Adam A, Torres D, Zhang X, Dobrolecki LE, Wei W, Lewis MT, Dave B, Chang JC, Landis MD, Creighton CJ, Mancini MA, Tweardy DJ. Drug-repositioning screening identified piperlongumine as a direct STAT3 inhibitor with potent activity against breast cancer. Oncogene. 2015 Mar 12; 34(11):1341-53. PMID: 24681959; PMCID: PMC4182178.
    18. Bolt MJ, Stossi F, Callison AM, Mancini MG, Dandekar R, Mancini MA. Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-? protein levels and activity. Oncogene. 2015 Jan 8; 34(2):154-64. PMID: 24441042; PMCID: PMC4871123.
    19. Szafran AT, Mancini MA. The myImageAnalysis project: a web-based application for high-content screening. Assay Drug Dev Technol. 2014 Jan-Feb; 12(1):87-99. PMID: 24547743; PMCID: PMC3934667.
    20. Bolt MJ, Stossi F, Newberg JY, Orjalo A, Johansson HE, Mancini MA. Coactivators enable glucocorticoid receptor recruitment to fine-tune estrogen receptor transcriptional responses. Nucleic Acids Res. 2013 Apr; 41(7):4036-48. PMID: 23444138; PMCID: PMC3627592.
    21. McDonough PM, Maciejewski-Lenoir D, Hartig SM, Hanna RA, Whittaker R, Heisel A, Nicoll JB, Buehrer BM, Christensen K, Mancini MG, Mancini MA, Edwards DP, Price JH. Differential phosphorylation of perilipin 1A at the initiation of lipolysis revealed by novel monoclonal antibodies and high content analysis. PLoS One. 2013; 8(2):e55511. PMID: 23405163; PMCID: PMC3566132.
    22. Hartig SM, He B, Newberg JY, Ochsner SA, Loose DS, Lanz RB, McKenna NJ, Buehrer BM, McGuire SE, Marcelli M, Mancini MA. Feed-forward inhibition of androgen receptor activity by glucocorticoid action in human adipocytes. Chem Biol. 2012 Sep 21; 19(9):1126-41. PMID: 22999881; PMCID: PMC4259876.
    23. Zhang X, Bolt M, Guertin MJ, Chen W, Zhang S, Cherrington BD, Slade DJ, Dreyton CJ, Subramanian V, Bicker KL, Thompson PR, Mancini MA, Lis JT, Coonrod SA. Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor ? target gene activation. Proc Natl Acad Sci U S A. 2012 Aug 14; 109(33):13331-6. PMID: 22853951; PMCID: PMC3421185.
    24. Mediwala SN, Sun H, Szafran AT, Hartig SM, Sonpavde G, Hayes TG, Thiagarajan P, Mancini MA, Marcelli M. The activity of the androgen receptor variant AR-V7 is regulated by FOXO1 in a PTEN-PI3K-AKT-dependent way. Prostate. 2013 Feb 15; 73(3):267-77. PMID: 22821817; PMCID: PMC3961010.
    25. Zakharov MN, Bhasin S, Szafran AT, Mancini MA, Jasuja R. Numerical framework to model temporally resolved multi-stage dynamic systems. Comput Methods Programs Biomed. 2012 Nov; 108(2):750-9. PMID: 22727632.
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    26. Lotti F, Corona G, Colpi GM, Filimberti E, Innocenti SD, Mancini M, Baldi E, Noci I, Forti G, Maggi M. Seminal vesicles ultrasound features in a cohort of infertility patients. Hum Reprod. 2012 Apr; 27(4):974-82. PMID: 22343552.
      View in: PubMed
    27. Spain RI, St George RJ, Salarian A, Mancini M, Wagner JM, Horak FB, Bourdette D. Body-worn motion sensors detect balance and gait deficits in people with multiple sclerosis who have normal walking speed. Gait Posture. 2012 Apr; 35(4):573-8. PMID: 22277368; PMCID: PMC3614340.
    28. Chen W, Chang B, Saha P, Hartig SM, Li L, Reddy VT, Yang Y, Yechoor V, Mancini MA, Chan L. Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation. Mol Cell Biol. 2012 Mar; 32(6):1099-111. PMID: 22269949; PMCID: PMC3295006.
    29. Slattery SD, Newberg JY, Szafran AT, Hall RM, Brinkley BR, Mancini MA. A framework for image-based classification of mitotic cells in asynchronous populations. Assay Drug Dev Technol. 2012 Apr; 10(2):161-78. PMID: 22084958; PMCID: PMC3323936.
    30. Uray IP, Rodenberg JM, Bissonnette RP, Brown PH, Mancini MA. Cancer-preventive rexinoid modulates neutral lipid contents of mammary epithelial cells through a peroxisome proliferator-activated receptor ?-dependent mechanism. Mol Pharmacol. 2012 Feb; 81(2):228-38. PMID: 22053058; PMCID: PMC3263950.
    31. Mancini MA, Wyrick-Waugh W. Consumer and practitioner perceptions of the harm reduction approach in a community mental health setting. Community Ment Health J. 2013 Feb; 49(1):14-24. PMID: 22009266.
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    32. Lotti F, Corona G, Colpi GM, Filimberti E, Degli Innocenti S, Mancini M, Baldi E, Noci I, Forti G, Adorini L, Maggi M. Elevated body mass index correlates with higher seminal plasma interleukin 8 levels and ultrasonographic abnormalities of the prostate in men attending an andrology clinic for infertility. J Endocrinol Invest. 2011 Nov; 34(10):e336-42. PMID: 21738005.
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    33. Ashcroft FJ, Newberg JY, Jones ED, Mikic I, Mancini MA. High content imaging-based assay to classify estrogen receptor-? ligands based on defined mechanistic outcomes. Gene. 2011 May 15; 477(1-2):42-52. PMID: 21256200; PMCID: PMC3086628.
    34. Hartig SM, He B, Long W, Buehrer BM, Mancini MA. Homeostatic levels of SRC-2 and SRC-3 promote early human adipogenesis. J Cell Biol. 2011 Jan 10; 192(1):55-67. PMID: 21220509; PMCID: PMC3019557.
    35. Szafran AT, Sun H, Hartig S, Shen Y, Mediwala SN, Bell J, McPhaul MJ, Mancini MA, Marcelli M. Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine. Adv Exp Med Biol. 2011; 707:63-5. PMID: 21691957.
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    36. Hartig SM, Newberg JY, Bolt MJ, Szafran AT, Marcelli M, Mancini MA. Automated microscopy and image analysis for androgen receptor function. Methods Mol Biol. 2011; 776:313-31. PMID: 21796534; PMCID: PMC4437203.
    37. Lotti F, Corona G, Mancini M, Filimberti E, Degli Innocenti S, Colpi GM, Baldi E, Noci I, Forti G, Adorini L, Maggi M. Ultrasonographic and clinical correlates of seminal plasma interleukin-8 levels in patients attending an andrology clinic for infertility. Int J Androl. 2011 Dec; 34(6 Pt 1):600-13. PMID: 20969602.
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    38. Pelosi E, Billè A, Skanjeti A, Errico L, Arena V, Ardissone F, Borasio P, Mancini M. Prognostic role of the PET parameter maximum standardized uptake value in non small cell lung cancer: analysis in tumour of diameter ? and <25 mm. Q J Nucl Med Mol Imaging. 2011 Feb; 55(1):72-80. PMID: 20539268.
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    39. García-Becerra R, Berno V, Ordaz-Rosado D, Sharp ZD, Cooney AJ, Mancini MA, Larrea F. Ligand-induced large-scale chromatin dynamics as a biosensor for the detection of estrogen receptor subtype selective ligands. Gene. 2010 Jun 15; 458(1-2):37-44. PMID: 20347019.
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    40. Zwart W, de Leeuw R, Rondaij M, Neefjes J, Mancini MA, Michalides R. The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen. J Cell Sci. 2010 Apr 15; 123(Pt 8):1253-61. PMID: 20332105.
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    41. Long W, Yi P, Amazit L, LaMarca HL, Ashcroft F, Kumar R, Mancini MA, Tsai SY, Tsai MJ, O'Malley BW. SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell. 2010 Feb 12; 37(3):321-32. PMID: 20159552; PMCID: PMC2824333.
    42. Narayanan R, Yepuru M, Szafran AT, Szwarc M, Bohl CE, Young NL, Miller DD, Mancini MA, Dalton JT. Discovery and mechanistic characterization of a novel selective nuclear androgen receptor exporter for the treatment of prostate cancer. Cancer Res. 2010 Jan 15; 70(2):842-51. PMID: 20068182.
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    43. Mancini MA, Linhorst DM. Harm reduction in community mental health settings. J Soc Work Disabil Rehabil. 2010; 9(2):130-47. PMID: 20730672.
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    44. Szafran AT, Hartig S, Sun H, Uray IP, Szwarc M, Shen Y, Mediwala SN, Bell J, McPhaul MJ, Mancini MA, Marcelli M. Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine. PLoS One. 2009; 4(12):e8179. PMID: 20011049; PMCID: PMC2785468.
    45. Slattery SD, Mancini MA, Brinkley BR, Hall RM. Aurora-C kinase supports mitotic progression in the absence of Aurora-B. Cell Cycle. 2009 Sep 15; 8(18):2984-94. PMID: 19713763.
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    46. Spath L, Rotilio V, Alessandrini M, Gambara G, De Angelis L, Mancini M, Mitsiadis TA, Vivarelli E, Naro F, Filippini A, Papaccio G. Explant-derived human dental pulp stem cells enhance differentiation and proliferation potentials. J Cell Mol Med. 2010 Jun; 14(6B):1635-44. PMID: 19602052; PMCID: PMC3829026.
    47. Zwart W, Rondaij M, Jalink K, Sharp ZD, Mancini MA, Neefjes J, Michalides R. Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1. Mol Endocrinol. 2009 Sep; 23(9):1335-45. PMID: 19477949; PMCID: PMC2737554.
    48. Giordano C, Cui Y, Barone I, Ando S, Mancini MA, Berno V, Fuqua SA. Growth factor-induced resistance to tamoxifen is associated with a mutation of estrogen receptor alpha and its phosphorylation at serine 305. Breast Cancer Res Treat. 2010 Jan; 119(1):71-85. PMID: 19205871; PMCID: PMC4482256.
    49. Szafran AT, Szwarc M, Marcelli M, Mancini MA. Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects. PLoS One. 2008; 3(11):e3605. PMID: 18978937; PMCID: PMC2572143.
    50. Berno V, Amazit L, Hinojos C, Zhong J, Mancini MG, Sharp ZD, Mancini MA. Activation of estrogen receptor-alpha by E2 or EGF induces temporally distinct patterns of large-scale chromatin modification and mRNA transcription. PLoS One. 2008; 3(5):e2286. PMID: 18509470; PMCID: PMC2386239.
    51. Huang Y, Qiu J, Dong S, Redell MS, Poli V, Mancini MA, Tweardy DJ. Stat3 isoforms, alpha and beta, demonstrate distinct intracellular dynamics with prolonged nuclear retention of Stat3beta mapping to its unique C-terminal end. J Biol Chem. 2007 Nov 30; 282(48):34958-67. PMID: 17855361.
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    52. Amazit L, Pasini L, Szafran AT, Berno V, Wu RC, Mielke M, Jones ED, Mancini MG, Hinojos CA, O'Malley BW, Mancini MA. Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Mol Cell Biol. 2007 Oct; 27(19):6913-32. PMID: 17646391; PMCID: PMC2099228.
    53. Prigozhina NL, Zhong L, Hunter EA, Miki? I, Callaway S, Roop DR, Mancini MA, Zacharias DA, Price JH, McDonough PM. Plasma membrane assays and three-compartment image cytometry for high content screening. Assay Drug Dev Technol. 2007 Feb; 5(1):29-48. PMID: 17355198.
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    54. Boonyaratanakornkit V, McGowan E, Sherman L, Mancini MA, Cheskis BJ, Edwards DP. The role of extranuclear signaling actions of progesterone receptor in mediating progesterone regulation of gene expression and the cell cycle. Mol Endocrinol. 2007 Feb; 21(2):359-75. PMID: 17138644.
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    55. Sharp ZD, Mancini MG, Hinojos CA, Dai F, Berno V, Szafran AT, Smith KP, Lele TP, Lele TT, Ingber DE, Mancini MA. Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent. J Cell Sci. 2006 Oct 1; 119(Pt 19):4101-16. PMID: 16968748.
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    56. Marcelli M, Stenoien DL, Szafran AT, Simeoni S, Agoulnik IU, Weigel NL, Moran T, Mikic I, Price JH, Mancini MA. Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility. J Cell Biochem. 2006 Jul 1; 98(4):770-88. PMID: 16440331.
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    57. Trubia M, Albano F, Cavazzini F, Cambrin GR, Quarta G, Fabbiano F, Ciambelli F, Magro D, Hernandezo JM, Mancini M, Diverio D, Pelicci PG, Coco FL, Mecucci C, Specchia G, Rocchi M, Liso V, Castoldi G, Cuneo A. Characterization of a recurrent translocation t(2;3)(p15-22;q26) occurring in acute myeloid leukaemia. Leukemia. 2006 Jan; 20(1):48-54. PMID: 16619048.
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    58. Berno V, Hinojos CA, Amazit L, Szafran AT, Mancini MA. High-resolution, high-throughput microscopy analyses of nuclear receptor and coregulator function. Methods Enzymol. 2006; 414:188-210. PMID: 17110193.
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    59. Ho TH, Savkur RS, Poulos MG, Mancini MA, Swanson MS, Cooper TA. Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy. J Cell Sci. 2005 Jul 1; 118(Pt 13):2923-33. PMID: 15961406.
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    60. Hinojos CA, Sharp ZD, Mancini MA. Molecular dynamics and nuclear receptor function. Trends Endocrinol Metab. 2005 Jan-Feb; 16(1):12-8. PMID: 15620544.
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    61. Corona G, Mannucci E, Mansani R, Petrone L, Bartolini M, Giommi R, Mancini M, Forti G, Maggi M. Aging and pathogenesis of erectile dysfunction. Int J Impot Res. 2004 Oct; 16(5):395-402. PMID: 15164087.
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    62. Unni E, Sun S, Nan B, McPhaul MJ, Cheskis B, Mancini MA, Marcelli M. Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence. Cancer Res. 2004 Oct 1; 64(19):7156-68. PMID: 15466214.
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    63. Sharp ZD, Stenoien DL, Mancini MG, Ouspenski II, Mancini MA. Inactivating Pit-1 mutations alter subnuclear dynamics suggesting a protein misfolding and nuclear stress response. J Cell Biochem. 2004 Jul 1; 92(4):664-78. PMID: 15211565.
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    64. Dong S, Stenoien DL, Qiu J, Mancini MA, Tweardy DJ. Reduced intranuclear mobility of APL fusion proteins accompanies their mislocalization and results in sequestration and decreased mobility of retinoid X receptor alpha. Mol Cell Biol. 2004 May; 24(10):4465-75. PMID: 15121864; PMCID: PMC400470.
    65. Contreras A, Hale TK, Stenoien DL, Rosen JM, Mancini MA, Herrera RE. The dynamic mobility of histone H1 is regulated by cyclin/CDK phosphorylation. Mol Cell Biol. 2003 Dec; 23(23):8626-36. PMID: 14612406; PMCID: PMC262667.
    66. Stenoien DL, Sen S, Mancini MA, Brinkley BR. Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. Cell Motil Cytoskeleton. 2003 Jun; 55(2):134-46. PMID: 12740874.
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    67. Dong S, Qiu J, Stenoien DL, Brinkley WR, Mancini MA, Tweardy DJ. Essential role for the dimerization domain of NuMA-RARalpha in its oncogenic activities and localization to NuMA sites within the nucleus. Oncogene. 2003 Feb 13; 22(6):858-68. PMID: 12584566.
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    68. Stenoien DL, Mielke M, Mancini MA. Intranuclear ataxin1 inclusions contain both fast- and slow-exchanging components. Nat Cell Biol. 2002 Oct; 4(10):806-10. PMID: 12360291.
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    69. Nye AC, Rajendran RR, Stenoien DL, Mancini MA, Katzenellenbogen BS, Belmont AS. Alteration of large-scale chromatin structure by estrogen receptor. Mol Cell Biol. 2002 May; 22(10):3437-49. PMID: 11971975; PMCID: PMC133805.
    70. Stenoien DL, Nye AC, Mancini MG, Patel K, Dutertre M, O'Malley BW, Smith CL, Belmont AS, Mancini MA. Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells. Mol Cell Biol. 2001 Jul; 21(13):4404-12. PMID: 11390668; PMCID: PMC87100.
    71. Herrmann CH, Mancini MA. The Cdk9 and cyclin T subunits of TAK/P-TEFb localize to splicing factor-rich nuclear speckle regions. J Cell Sci. 2001 Apr; 114(Pt 8):1491-503. PMID: 11282025.
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    72. Stenoien DL, Patel K, Mancini MG, Dutertre M, Smith CL, O'Malley BW, Mancini MA. FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nat Cell Biol. 2001 Jan; 3(1):15-23. PMID: 11146621.
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    73. Mancini M, Negri L, Maggi M, Nerva F, Forti G, Colpi GM. [Doppler color ultrasonography in the diagnosis of erectile dysfunction of vascular origin]. Arch Ital Urol Androl. 2000 Dec; 72(4):361-5. PMID: 11221072.
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    74. Filippi S, Mancini M, Amerini S, Bartolini M, Natali A, Mancina R, Forti G, Ledda F, Maggi M. Functional adenosine receptors in human corpora cavernosa. Int J Androl. 2000 Aug; 23(4):210-7. PMID: 10886423.
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    75. Mancini M, Bartolini M, Maggi M, Innocenti P, Villari N, Forti G. Duplex ultrasound evaluation of cavernosal peak systolic velocity and waveform acceleration in the penile flaccid state: clinical significance in the assessment of the arterial supply in patients with erectile dysfunction. Int J Androl. 2000 Aug; 23(4):199-204. PMID: 10886421.
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    76. Stenoien DL, Mancini MG, Patel K, Allegretto EA, Smith CL, Mancini MA. Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1. Mol Endocrinol. 2000 Apr; 14(4):518-34. PMID: 10770489.
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    77. Prakash SK, Paylor R, Jenna S, Lamarche-Vane N, Armstrong DL, Xu B, Mancini MA, Zoghbi HY. Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA. Hum Mol Genet. 2000 Mar 1; 9(4):477-88. PMID: 10699171.
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    78. Simeoni S, Mancini MA, Stenoien DL, Marcelli M, Weigel NL, Zanisi M, Martini L, Poletti A. Motoneuronal cell death is not correlated with aggregate formation of androgen receptors containing an elongated polyglutamine tract. Hum Mol Genet. 2000 Jan 1; 9(1):133-44. PMID: 10587588.
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    79. Stenoien DL, Simeoni S, Sharp ZD, Mancini MA. Subnuclear dynamics and transcription factor function. J Cell Biochem Suppl. 2000; Suppl 35:99-106. PMID: 11389538.
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    80. Mancini M, Rubba P. The Mediterranean diet in Italy. World Rev Nutr Diet. 2000; 87:114-26. PMID: 10929530.
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    81. Nazareth LV, Stenoien DL, Bingman WE, James AJ, Wu C, Zhang Y, Edwards DP, Mancini M, Marcelli M, Lamb DJ, Weigel NL. A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1) Mol Endocrinol. 1999 Dec; 13(12):2065-75. PMID: 10598582.
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    82. Van Hooser AA, Mancini MA, Allis CD, Sullivan KF, Brinkley BR. The mammalian centromere: structural domains and the attenuation of chromatin modeling. FASEB J. 1999 Dec; 13 Suppl 2:S216-20. PMID: 10619130.
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    83. Ottonello L, Amelotti M, Barbera P, Dapino P, Mancini M, Tortolina G, Dallegri F. Chemoattractant-induced release of elastase by tumor necrosis factor-primed human neutrophils: auto-regulation by endogenous adenosine. Inflamm Res. 1999 Dec; 48(12):637-42. PMID: 10669115.
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    84. Assmann G, Carmena R, Cullen P, Fruchart JC, Jossa F, Lewis B, Mancini M, Paoletti R. Coronary heart disease: reducing the risk: a worldwide view. International Task Force for the Prevention of Coronary Heart Disease. Circulation. 1999 Nov 2; 100(18):1930-8. PMID: 10545439.
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    85. Kazansky AV, Kabotyanski EB, Wyszomierski SL, Mancini MA, Rosen JM. Differential effects of prolactin and src/abl kinases on the nuclear translocation of STAT5B and STAT5A. J Biol Chem. 1999 Aug 6; 274(32):22484-92. PMID: 10428824.
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    86. Stenoien DL, Cummings CJ, Adams HP, Mancini MG, Patel K, DeMartino GN, Marcelli M, Weigel NL, Mancini MA. Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone. Hum Mol Genet. 1999 May; 8(5):731-41. PMID: 10196362.
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    87. Mancini MG, Liu B, Sharp ZD, Mancini MA. Subnuclear partitioning and functional regulation of the Pit-1 transcription factor. J Cell Biochem. 1999 Mar 1; 72(3):322-38. PMID: 10022514.
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    88. Van Hooser A, Goodrich DW, Allis CD, Brinkley BR, Mancini MA. Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation. J Cell Sci. 1998 Dec; 111 ( Pt 23):3497-506. PMID: 9811564.
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    89. Stenoien D, Sharp ZD, Smith CL, Mancini MA. Functional subnuclear partitioning of transcription factors. J Cell Biochem. 1998 Aug 1; 70(2):213-21. PMID: 9671227.
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    90. Cummings CJ, Mancini MA, Antalffy B, DeFranco DB, Orr HT, Zoghbi HY. Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1. Nat Genet. 1998 Jun; 19(2):148-54. PMID: 9620770.
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    91. Hendzel MJ, Wei Y, Mancini MA, Van Hooser A, Ranalli T, Brinkley BR, Bazett-Jones DP, Allis CD. Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma. 1997 Nov; 106(6):348-60. PMID: 9362543.
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    92. Mancini MA, He D, Ouspenski II, Brinkley BR. Dynamic continuity of nuclear and mitotic matrix proteins in the cell cycle. J Cell Biochem. 1996 Aug; 62(2):158-64. PMID: 8844395.
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    93. Mancini M, Bartolini M, Maggi M, Innocenti P, Forti G. The presence of arterial anatomical variations can affect the results of duplex sonographic evaluation of penile vessels in impotent patients. J Urol. 1996 Jun; 155(6):1919-23. PMID: 8618288.
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    94. Chatterjee B, Song CS, Jung MH, Chen S, Walter CA, Herbert DC, Weaker FJ, Mancini MA, Roy AK. Targeted overexpression of androgen receptor with a liver-specific promoter in transgenic mice. Proc Natl Acad Sci U S A. 1996 Jan 23; 93(2):728-33. PMID: 8570624; PMCID: PMC40122.
    95. Zhu X, Mancini MA, Chang KH, Liu CY, Chen CF, Shan B, Jones D, Yang-Feng TL, Lee WH. Characterization of a novel 350-kilodalton nuclear phosphoprotein that is specifically involved in mitotic-phase progression. Mol Cell Biol. 1995 Sep; 15(9):5017-29. PMID: 7651420; PMCID: PMC230749.
    96. Zhu X, Chang KH, He D, Mancini MA, Brinkley WR, Lee WH. The C terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting, and dimerization. J Biol Chem. 1995 Aug 18; 270(33):19545-50. PMID: 7642639.
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    97. Durfee T, Mancini MA, Jones D, Elledge SJ, Lee WH. The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing. J Cell Biol. 1994 Nov; 127(3):609-22. PMID: 7525595; PMCID: PMC2120229.
    98. Mancini MA, Shan B, Nickerson JA, Penman S, Lee WH. The retinoblastoma gene product is a cell cycle-dependent, nuclear matrix-associated protein. Proc Natl Acad Sci U S A. 1994 Jan 4; 91(1):418-22. PMID: 8278403; PMCID: PMC42959.
    99. Lee WH, Xu Y, Hong F, Durfee T, Mancini MA, Ueng YC, Chen PL, Riley D. The corral hypothesis: a novel regulatory mode for retinoblastoma protein function. Cold Spring Harb Symp Quant Biol. 1994; 59:97-107. PMID: 7587136.
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    100. Stipa S, Danesi DT, Modini C, Cicconetti F, Mauro F, Schillaci A, Mecozzi A, Nicolanti V, Stipa F, Mancini M, et al. The importance of heterogeneity and of multiple site sampling in the prospective determination of deoxyribonucleic acid flow cytometry. Surg Gynecol Obstet. 1993 May; 176(5):427-34. PMID: 8386859.
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    101. Mancini MA, Song CS, Rao TR, Chatterjee B, Roy AK. Spatio-temporal expression of estrogen sulfotransferase within the hepatic lobule of male rats: implication of in situ estrogen inactivation in androgen action. Endocrinology. 1992 Sep; 131(3):1541-6. PMID: 1380444.
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    102. Magnuson VL, Young M, Schattenberg DG, Mancini MA, Chen DL, Steffensen B, Klebe RJ. The alternative splicing of fibronectin pre-mRNA is altered during aging and in response to growth factors. J Biol Chem. 1991 Aug 5; 266(22):14654-62. PMID: 1713586.
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    103. Mancini MA, Chatterjee B, Roy AK. Age-dependent reversal of the lobular distribution of androgen-inducible alpha 2u globulin and androgen-repressible SMP-2 in rat liver. J Histochem Cytochem. 1991 Apr; 39(4):401-5. PMID: 1706374.
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    104. Song CS, Rao TR, Demyan WF, Mancini MA, Chatterjee B, Roy AK. Androgen receptor messenger ribonucleic acid (mRNA) in the rat liver: changes in mRNA levels during maturation, aging, and calorie restriction. Endocrinology. 1991 Jan; 128(1):349-56. PMID: 1986927.
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    105. Chatterjee B, Mancini MA, Roy AK. The senescence marker protein (SMP-2) of the rat liver: purification, immunochemical characterization and age-dependent regulation. Biochim Biophys Acta. 1990 May 16; 1034(2):162-9. PMID: 2354191.
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    106. Mancini MA, Kennedy A, Frank RN, Trese MT, Hartzer M, Hukku B, Lin LR. A cell line derived from non-neoplastic human neuroretinal cells. Invest Ophthalmol Vis Sci. 1989 Mar; 30(3):499-508. PMID: 2925321.
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    107. Mancini MA, Majumdar D, Chatterjee B, Roy AK. Alpha 2u-globulin in modified sebaceous glands with pheromonal functions: localization of the protein and its mRNA in preputial, meibomian, and perianal glands. J Histochem Cytochem. 1989 Feb; 37(2):149-57. PMID: 2463299.
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    108. Weber ML, Mancini MA, Frank RN. Retinovitreal neovascularization in the Royal College of Surgeons rat. Curr Eye Res. 1989 Jan; 8(1):61-74. PMID: 2468452.
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    109. Olson MJ, Mancini MA, Garg BD, Roy AK. Leupeptin-mediated alteration of renal phagolysosomes: similarity to hyaline droplet nephropathy of male rats exposed to unleaded gasoline. Toxicol Lett. 1988 Jun; 41(3):245-54. PMID: 2453947.
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    110. Das A, Frank RN, Weber ML, Kennedy A, Reidy CA, Mancini MA. ATP causes retinal pericytes to contract in vitro. Exp Eye Res. 1988 Mar; 46(3):349-62. PMID: 3258246.
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    111. Murty CV, Mancini MA, Chatterjee B, Roy AK. Changes in transcriptional activity and matrix association of alpha 2u-globulin gene family in the rat liver during maturation and aging. Biochim Biophys Acta. 1988 Jan 25; 949(1):27-34. PMID: 2446666.
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    112. Murty CV, Sarkar FH, Mancini MA, Roy AK. Sex-independent synthesis of alpha 2u-globulin and its messenger ribonucleic acid in the rat preputial gland: biochemical and immunocytochemical analyses. Endocrinology. 1987 Sep; 121(3):1000-5. PMID: 2441975.
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    113. Frank RN, Dutta S, Mancini MA. Pericyte coverage is greater in the retinal than in the cerebral capillaries of the rat. Invest Ophthalmol Vis Sci. 1987 Jul; 28(7):1086-91. PMID: 3596989.
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    114. Sarkar FH, Mancini MA, Nag AC, Roy AK. Cellular interactions in the hormonal induction of alpha 2u-globulin in rat liver. J Endocrinol. 1986 Nov; 111(2):205-8. PMID: 2432143.
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    115. Kennedy A, Frank RN, Mancini MA. In vitro production of glycosaminoglycans by retinal microvessel cells and lens epithelium. Invest Ophthalmol Vis Sci. 1986 May; 27(5):746-54. PMID: 3700024.
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    116. Mancini MA, Frank RN, Keirn RJ, Kennedy A, Khoury JK. Does the retinal pigment epithelium polarize the choriocapillaris? Invest Ophthalmol Vis Sci. 1986 Mar; 27(3):336-45. PMID: 3949463.
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    117. Frank RN, Mancini MA. Presumed retinovitreal neovascularization in dystrophic retinas of spontaneously hypertensive rats. Invest Ophthalmol Vis Sci. 1986 Mar; 27(3):346-55. PMID: 2419273.
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    118. Kennedy A, Frank RN, Mancini MA, Lande M. Collagens of the retinal microvascular basement membrane and of retinal microvascular cells in vitro. Exp Eye Res. 1986 Feb; 42(2):177-99. PMID: 3516712.
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    119. Frank RN, Keirn RJ, Keirn GV, Mancini MA, Khoury JK. Retinal dystrophy: development retarded by galactose feeding in spontaneously hypertensive rats. Science. 1986 Jan 24; 231(4736):376-8. PMID: 3941900.
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    120. Roy AK, Sarkar FH, Nag AC, Mancini MA. Role of cytodifferentiation and cell-cell communication in the androgen dependent expression of alpha 2u globulin gene in rat liver. Prog Clin Biol Res. 1986; 226:401-15. PMID: 2433699.
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    121. LAVITOLA G, MANCINI M. [Effects of nicotinic acid on the total level of blood cholesterol and its alpha and beta lipoprotein fractions]. Osp Psichiatr. 1956 Apr-Jun; 24(2):153-6. PMID: 13388369.
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