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MARGARET GOODELL

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Cell & Gene Therapy
    DivisionCenter for Cell & Gene Therapy

    TitleChair
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Human Genetics
    DivisionMolecular & Human Genetics

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pathology & Immunology
    DivisionImmunology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pediatrics
    DivisionPediatrics-Hem/Onc Cell & Gene The

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentHuffington Center on Aging
    DivisionHuffington Ctr on Aging


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    R55CA081179     (GOODELL, MARGARET)Apr 1, 1999 - Mar 31, 2001
    NIH/NCI
    CD34NEGATIVE HUMAN HEMATOPOIETIC STEM CELLS
    Role: Principal Investigator
    R01CA081179     (GOODELL, MARGARET)Apr 1, 2000 - Mar 31, 2006
    NIH/NCI
    CD34 NEGATIVE HUMAN HEMATOPOIETIC STEM CELLS
    Role: Principal Investigator
    T32DK060445     (GOODELL, MARGARET A.)Sep 30, 2002 - Sep 29, 2008
    NIH/NIDDK
    Hematology Training Program
    Role: Principal Investigator
    S10RR017895     (GOODELL, MARGARET)Apr 1, 2003 - Mar 31, 2004
    NIH/NCRR
    ABI PRISM 7900 Sequence Detection System
    Role: Principal Investigator
    R13GM073351     (GOODELL, MARGARET)Sep 3, 2004 - Aug 31, 2005
    NIH/NIGMS
    Conference on Molecular Regulation of Stem Cells
    Role: Principal Investigator
    S10RR021054     (GOODELL, MARGARET)Feb 1, 2005 - Jan 31, 2006
    NIH/NCRR
    BD LSRII Four Laser Analytical Flow Cytometer
    Role: Principal Investigator
    R01DK075355     (GOODELL, MARGARET)Sep 30, 2005 - Aug 31, 2010
    NIH/NIDDK
    Safe and Efficient Generation of hES-derived Bone Marrow
    Role: Principal Investigator
    P01GM081627     (GOODELL, MARGARET)Sep 1, 2007 - Aug 31, 2014
    NIH/NIGMS
    Regulatory Networks in Human Embryonic Stem Cells
    Role: Principal Investigator
    R01DK058192     (GOODELL, MARGARET)Jul 16, 2009 - Sep 30, 2011
    NIH/NIDDK
    Hematopoietic Stem Cell Differentiation and Commitment
    Role: Principal Investigator
    R21AG034451     (GOODELL, MARGARET)Aug 15, 2009 - Jul 31, 2011
    NIH/NIA
    Cell Fate Tracking in the Aging Hematopoietic System
    Role: Principal Investigator
    R56DK092883     (GOODELL, MARGARET)Jul 1, 2011 - Jun 30, 2012
    NIH/NIDDK
    Regulation of Hematopoietic Progenitors by de novo DNA Methylation
    Role: Principal Investigator
    R01DK092883     (GOODELL, MARGARET A.)Sep 1, 2013 - May 31, 2021
    NIH/NIDDK
    Regulation of Hematopoietic Progenitors by de novo DNA methylation
    Role: Principal Investigator
    R01CA183252     (GOODELL, MARGARET A.)Sep 11, 2014 - Aug 31, 2024
    NIH/NCI
    DNMT3A in Development of Hematologic Malignancies
    Role: Principal Investigator
    U01CA236972     (GOODELL, MARGARET A.)Jun 4, 2019 - May 31, 2021
    NIH/NCI
    Clonal Hematopoiesis, Aging and Genome Stability in PPM1D Mutants
    Role: Principal Investigator
    R01CA237291     (GOODELL, MARGARET A.)Jul 1, 2019 - Jun 30, 2024
    NIH/NCI
    PPM1D in Clonal Hematopoiesis and Malignancies
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sportoletti P, Sorcini D, Guzman AG, Reyes JM, Stella A, Marra A, Sartori S, Brunetti L, Rossi R, Papa BD, Adamo FM, Pianigiani G, Betti C, Scialdone A, Guarente V, Spinozzi G, Tini V, Martelli MP, Goodell MA, Falini B. Bcor deficiency perturbs erythro-megakaryopoiesis and cooperates with Dnmt3a loss in acute erythroid leukemia onset in mice. Leukemia. 2020 Nov 06. PMID: 33159179.
      Citations:    Fields:    
    2. Challen GA, Goodell MA. Clonal hematopoiesis: mechanisms driving dominance of stem cell clones. Blood. 2020 Oct 01; 136(14):1590-1598. PMID: 32746453.
      Citations: 2     Fields:    
    3. Tovy A, Reyes JM, Gundry MC, Brunetti L, Lee-Six H, Petljak M, Park HJ, Guzman AG, Rosas C, Jeffries AR, Baple E, Mill J, Crosby AH, Sency V, Xin B, Machado HE, Castillo D, Weitzel JN, Li W, Stratton MR, Campbell PJ, Wang H, Sanders MA, Goodell MA. Tissue-Biased Expansion of DNMT3A-Mutant Clones in a Mosaic Individual Is Associated with Conserved Epigenetic Erosion. Cell Stem Cell. 2020 Aug 06; 27(2):326-335.e4. PMID: 32673568.
      Citations: 1     Fields:    
    4. Datar GK, Goodell MA. Where There's Smoke, There's Fire: Inflammation Drives MDS. Trends Immunol. 2020 07; 41(7):558-560. PMID: 32513619.
      Citations:    Fields:    Translation:Humans
    5. Zhang X, Jeong M, Huang X, Wang XQ, Wang X, Zhou W, Shamim MS, Gore H, Himadewi P, Liu Y, Bochkov ID, Reyes J, Doty M, Huang YH, Jung H, Heikamp E, Aiden AP, Li W, Su J, Aiden EL, Goodell MA. Large DNA Methylation Nadirs Anchor Chromatin Loops Maintaining Hematopoietic Stem Cell Identity. Mol Cell. 2020 05 07; 78(3):506-521.e6. PMID: 32386543.
      Citations: 3     Fields:    Translation:HumansCells
    6. Gundry MC, Goodell MA, Brunetti L. It's All About MEis: Menin-MLL Inhibition Eradicates NPM1-Mutated and MLL-Rearranged Acute Leukemias in Mice. Cancer Cell. 2020 03 16; 37(3):267-269. PMID: 32183947.
      Citations: 2     Fields:    Translation:AnimalsCells
    7. Zhang X, Wang X, Wang XQD, Su J, Putluri N, Zhou T, Qu Y, Jeong M, Guzman A, Rosas C, Huang Y, Sreekumar A, Li W, Goodell MA. Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis. Blood. 2020 03 12; 135(11):845-856. PMID: 31932841.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    8. Lavery LA, Ure K, Wan YW, Luo C, Trostle AJ, Wang W, Jin H, Lopez J, Lucero J, Durham MA, Castanon R, Nery JR, Liu Z, Goodell M, Ecker JR, Behrens MM, Zoghbi HY. Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome. Elife. 2020 03 11; 9. PMID: 32159514.
      Citations: 6     Fields:    
    9. Guo L, Li J, Zeng H, Guzman AG, Li T, Lee M, Zhou Y, Goodell MA, Stephan C, Davies PJA, Dawson MA, Sun D, Huang Y. A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells. Nat Commun. 2020 02 06; 11(1):740. PMID: 32029739.
      Citations:    Fields:    Translation:HumansAnimalsCells
    10. Choi BK, Fujiwara K, Dayaram T, Darlington Y, Dickerson J, Goodell MA, Donehower LA. WIP1 dephosphorylation of p27Kip1 Serine 140 destabilizes p27Kip1 and reverses anti-proliferative effects of ATM phosphorylation. Cell Cycle. 2020 02; 19(4):479-491. PMID: 31959038.
      Citations:    
    11. King KY, Huang Y, Nakada D, Goodell MA. Environmental influences on clonal hematopoiesis. Exp Hematol. 2020 03; 83:66-73. PMID: 31893524.
      Citations: 5     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    12. Zeng H, He H, Guo L, Li J, Lee M, Han W, Guzman AG, Zang S, Zhou Y, Zhang X, Goodell MA, King KY, Sun D, Huang Y. Antibiotic treatment ameliorates Ten-eleven translocation 2 (TET2) loss-of-function associated hematological malignancies. Cancer Lett. 2019 12 28; 467:1-8. PMID: 31563562.
      Citations: 2     Fields:    Translation:AnimalsCells
    13. Rau RE, Goodell MA. Measure Twice, Cut Once: Therapeutic Editing of HSPCs Requires Precise Planning. Cell Stem Cell. 2019 04 04; 24(4):511-512. PMID: 30951659.
      Citations:    Fields:    Translation:Cells
    14. Goodell MA, Bodine DM. Single-cell technology meets hematology: introduction to a review series. Blood. 2019 03 28; 133(13):1387-1388. PMID: 30728147.
      Citations:    Fields:    Translation:HumansCells
    15. Sandoval JE, Huang YH, Muise A, Goodell MA, Reich NO. Mutations in the DNMT3A DNA methyltransferase in acute myeloid leukemia patients cause both loss and gain of function and differential regulation by protein partners. J Biol Chem. 2019 03 29; 294(13):4898-4910. PMID: 30705090.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    16. Luo C, Lee QY, Wapinski O, Castanon R, Nery JR, Mall M, Kareta MS, Cullen SM, Goodell MA, Chang HY, Wernig M, Ecker JR. Global DNA methylation remodeling during direct reprogramming of fibroblasts to neurons. Elife. 2019 01 15; 8. PMID: 30644360.
      Citations: 9     Fields:    Translation:AnimalsCells
    17. Brunetti L, Gundry MC, Goodell MA. New insights into the biology of acute myeloid leukemia with mutated NPM1. Int J Hematol. 2019 Aug; 110(2):150-160. PMID: 30632059.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    18. Lei Y, Huang YH, Goodell MA. DNA methylation and de-methylation using hybrid site-targeting proteins. Genome Biol. 2018 11 06; 19(1):187. PMID: 30400938.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    19. Hsu JI, Dayaram T, Tovy A, De Braekeleer E, Jeong M, Wang F, Zhang J, Heffernan TP, Gera S, Kovacs JJ, Marszalek JR, Bristow C, Yan Y, Garcia-Manero G, Kantarjian H, Vassiliou G, Futreal PA, Donehower LA, Takahashi K, Goodell MA. PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy. Cell Stem Cell. 2018 11 01; 23(5):700-713.e6. PMID: 30388424.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    20. Brunetti L, Gundry MC, Sorcini D, Guzman AG, Huang YH, Ramabadran R, Gionfriddo I, Mezzasoma F, Milano F, Nabet B, Buckley DL, Kornblau SM, Lin CY, Sportoletti P, Martelli MP, Falini B, Goodell MA. Mutant NPM1 Maintains the Leukemic State through HOX Expression. Cancer Cell. 2018 09 10; 34(3):499-512.e9. PMID: 30205049.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    21. Su J, Huang YH, Cui X, Wang X, Zhang X, Lei Y, Xu J, Lin X, Chen K, Lv J, Goodell MA, Li W. Homeobox oncogene activation by pan-cancer DNA hypermethylation. Genome Biol. 2018 08 10; 19(1):108. PMID: 30097071.
      Citations: 14     Fields:    Translation:HumansCells
    22. Gu T, Lin X, Cullen SM, Luo M, Jeong M, Estecio M, Shen J, Hardikar S, Sun D, Su J, Rux D, Guzman A, Lee M, Qi LS, Chen JJ, Kyba M, Huang Y, Chen T, Li W, Goodell MA. DNMT3A and TET1 cooperate to regulate promoter epigenetic landscapes in mouse embryonic stem cells. Genome Biol. 2018 07 12; 19(1):88. PMID: 30001199.
      Citations: 21     Fields:    Translation:AnimalsCells
    23. Brunetti L, Gundry MC, Kitano A, Nakada D, Goodell MA. Highly Efficient Gene Disruption of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9. J Vis Exp. 2018 04 10; (134). PMID: 29708546.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    24. Jeong M, Park HJ, Celik H, Ostrander EL, Reyes JM, Guzman A, Rodriguez B, Lei Y, Lee Y, Ding L, Guryanova OA, Li W, Goodell MA, Challen GA. Loss of Dnmt3a Immortalizes Hematopoietic Stem Cells In Vivo. Cell Rep. 2018 04 03; 23(1):1-10. PMID: 29617651.
      Citations: 17     Fields:    Translation:AnimalsCells
    25. Tan Q, Brunetti L, Rousseaux MWC, Lu HC, Wan YW, Revelli JP, Liu Z, Goodell MA, Zoghbi HY. Loss of Capicua alters early T cell development and predisposes mice to T cell lymphoblastic leukemia/lymphoma. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):E1511-E1519. PMID: 29382756.
      Citations: 9     Fields:    Translation:AnimalsCells
    26. Huang YH, Su J, Lei Y, Brunetti L, Gundry MC, Zhang X, Jeong M, Li W, Goodell MA. DNA epigenome editing using CRISPR-Cas SunTag-directed DNMT3A. Genome Biol. 2017 09 18; 18(1):176. PMID: 28923089.
      Citations: 27     Fields:    Translation:HumansCells
    27. Lei Y, Zhang X, Su J, Jeong M, Gundry MC, Huang YH, Zhou Y, Li W, Goodell MA. Targeted DNA methylation in vivo using an engineered dCas9-MQ1 fusion protein. Nat Commun. 2017 07 11; 8:16026. PMID: 28695892.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    28. Brunetti L, Gundry MC, Goodell MA. DNMT3A in Leukemia. Cold Spring Harb Perspect Med. 2017 Feb 01; 7(2). PMID: 28003281.
      Citations: 20     Fields:    Translation:HumansCells
    29. Jeong M, Guzman AG, Goodell MA. Genome-Wide Analysis of DNA Methylation in Hematopoietic Cells: DNA Methylation Analysis by WGBS. Methods Mol Biol. 2017; 1633:137-149. PMID: 28735485.
      Citations:    Fields:    Translation:HumansCells
    30. Gundry MC, Brunetti L, Lin A, Mayle AE, Kitano A, Wagner D, Hsu JI, Hoegenauer KA, Rooney CM, Goodell MA, Nakada D. Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9. Cell Rep. 2016 10 25; 17(5):1453-1461. PMID: 27783956.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    31. Karlstaedt A, Zhang X, Vitrac H, Harmancey R, Vasquez H, Wang JH, Goodell MA, Taegtmeyer H. Oncometabolite d-2-hydroxyglutarate impairs a-ketoglutarate dehydrogenase and contractile function in rodent heart. Proc Natl Acad Sci U S A. 2016 09 13; 113(37):10436-41. PMID: 27582470.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    32. Yang L, Rodriguez B, Mayle A, Park HJ, Lin X, Luo M, Jeong M, Curry CV, Kim SB, Ruau D, Zhang X, Zhou T, Zhou M, Rebel VI, Challen GA, Göttgens B, Lee JS, Rau R, Li W, Goodell MA. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell. 2016 08 08; 30(2):363-365. PMID: 27505680.
      Citations: 10     Fields:    
    33. Zhang X, Su J, Jeong M, Ko M, Huang Y, Park HJ, Guzman A, Lei Y, Huang YH, Rao A, Li W, Goodell MA. DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells. Nat Genet. 2016 09; 48(9):1014-23. PMID: 27428748.
      Citations: 56     Fields:    Translation:AnimalsCells
    34. Rau RE, Rodriguez BA, Luo M, Jeong M, Rosen A, Rogers JH, Campbell CT, Daigle SR, Deng L, Song Y, Sweet S, Chevassut T, Andreeff M, Kornblau SM, Li W, Goodell MA. DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia. Blood. 2016 08 18; 128(7):971-81. PMID: 27335278.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    35. Yang L, Rodriguez B, Mayle A, Park HJ, Lin X, Luo M, Jeong M, Curry CV, Kim SB, Ruau D, Zhang X, Zhou T, Zhou M, Rebel VI, Challen GA, Gottgens B, Lee JS, Rau R, Li W, Goodell MA. DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias. Cancer Cell. 2016 06 13; 29(6):922-934. PMID: 27300438.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    36. Eckstein OS, Wang L, Punia JN, Kornblau SM, Andreeff M, Wheeler DA, Goodell MA, Rau RE. Mixed-phenotype acute leukemia (MPAL) exhibits frequent mutations in DNMT3A and activated signaling genes. Exp Hematol. 2016 08; 44(8):740-4. PMID: 27208809.
      Citations: 11     Fields:    Translation:HumansCells
    37. Goodell MA, Rando TA. Stem cells and healthy aging. Science. 2015 Dec 04; 350(6265):1199-204. PMID: 26785478.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    38. An J, González-Avalos E, Chawla A, Jeong M, López-Moyado IF, Li W, Goodell MA, Chavez L, Ko M, Rao A. Acute loss of TET function results in aggressive myeloid cancer in mice. Nat Commun. 2015 Nov 26; 6:10071. PMID: 26607761.
      Citations: 39     Fields:    Translation:AnimalsCells
    39. Wang J, Wegener JE, Huang TW, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J, Starwalt R, McDaniel L, Ward CS, Parra D, Newcomb B, Lao U, Nourigat C, Flowers DA, Cullen S, Jorstad NL, Yang Y, Glaskova L, Vigneau S, Kozlitina J, Yetman MJ, Jankowsky JL, Reichardt SD, Reichardt HM, Gärtner J, Bartolomei MS, Fang M, Loeb K, Keene CD, Bernstein I, Goodell M, Brat DJ, Huppke P, Neul JL, Bedalov A, Pieper AA. Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome. Nature. 2015 Sep 24; 525(7570):552. PMID: 26176914.
      Citations:    Fields:    
    40. King KY, Matatall KA, Shen CC, Goodell MA, Swierczek SI, Prchal JT. Comparative long-term effects of interferon a and hydroxyurea on human hematopoietic progenitor cells. Exp Hematol. 2015 Oct; 43(10):912-918.e2. PMID: 26072330.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    41. Artandi SE, Blau HM, de Haan G, Geiger H, Goodell MA, Jones L, Levine RL, Muñoz-Cánoves P, Rodewald HR, Wagers A, Wang ZQ, Yamashita Y. Stem Cells and Aging: What's Next? Cell Stem Cell. 2015 Jun 04; 16(6):578-81. PMID: 26247067.
      Citations: 4     Fields:    Translation:HumansCells
    42. Gibson BW, Boles NC, Souroullas GP, Herron AJ, Fraley JK, Schwiebert RS, Sharp JJ, Goodell MA. Comparison of Cesium-137 and X-ray Irradiators by Using Bone Marrow Transplant Reconstitution in C57BL/6J Mice. Comp Med. 2015 Jun; 65(3):165-72. PMID: 26141441.
      Citations: 5     Fields:    Translation:Animals
    43. Wang J, Wegener JE, Huang TW, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J, Starwalt R, McDaniel L, Ward CS, Parra D, Newcomb B, Lao U, Nourigat C, Flowers DA, Cullen S, Jorstad NL, Yang Y, Glaskova L, Vingeau S, Vigneau S, Kozlitina J, Yetman MJ, Jankowsky JL, Reichardt SD, Reichardt HM, Gärtner J, Bartolomei MS, Fang M, Loeb K, Keene CD, Bernstein I, Goodell M, Brat DJ, Huppke P, Neul JL, Bedalov A, Pieper AA. Wild-type microglia do not reverse pathology in mouse models of Rett syndrome. Nature. 2015 May 21; 521(7552):E1-4. PMID: 25993969.
      Citations: 44     Fields:    Translation:AnimalsCells
    44. Goodell MA, Nguyen H, Shroyer N. Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments. Nat Rev Mol Cell Biol. 2015 May; 16(5):299-309. PMID: 25907613.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    45. Luo M, Jeong M, Sun D, Park HJ, Rodriguez BA, Xia Z, Yang L, Zhang X, Sheng K, Darlington GJ, Li W, Goodell MA. Long non-coding RNAs control hematopoietic stem cell function. Cell Stem Cell. 2015 Apr 02; 16(4):426-38. PMID: 25772072.
      Citations: 46     Fields:    Translation:AnimalsCells
    46. Goodell M. Introduction to a review series on hematopoietic stem cells. Blood. 2015 Apr 23; 125(17):2587. PMID: 25762178.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    47. Yang L, Rau R, Goodell MA. DNMT3A in haematological malignancies. Nat Rev Cancer. 2015 Mar; 15(3):152-65. PMID: 25693834.
      Citations: 127     Fields:    Translation:HumansCells
    48. Mayle A, Yang L, Rodriguez B, Zhou T, Chang E, Curry CV, Challen GA, Li W, Wheeler D, Rebel VI, Goodell MA. Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation. Blood. 2015 Jan 22; 125(4):629-38. PMID: 25416277.
      Citations: 85     Fields:    Translation:AnimalsCells
    49. Cullen SM, Goodell MA. Dynamic DNA methylation discovered during HSC differentiation. . 2015; 14(5):693-4. PMID: 25714123.
      Citations:    
    50. Challen GA, Sun D, Mayle A, Jeong M, Luo M, Rodriguez B, Mallaney C, Celik H, Yang L, Xia Z, Cullen S, Berg J, Zheng Y, Darlington GJ, Li W, Goodell MA. Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells. Cell Stem Cell. 2014 Sep 04; 15(3):350-364. PMID: 25130491.
      Citations: 98     Fields:    Translation:AnimalsCells
    51. Jeong M, Goodell MA. New answers to old questions from genome-wide maps of DNA methylation in hematopoietic cells. Exp Hematol. 2014 Aug; 42(8):609-17. PMID: 24993071.
      Citations: 14     Fields:    Translation:AnimalsCells
    52. Goodell MA. A gallon of sweat to make a pint of blood. J Exp Med. 2014 Jun 30; 211(7):1271-2. PMID: 24980745.
      Citations:    Fields:    Translation:AnimalsCells
    53. Rodgers JT, King KY, Brett JO, Cromie MJ, Charville GW, Maguire KK, Brunson C, Mastey N, Liu L, Tsai CR, Goodell MA, Rando TA. mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert). Nature. 2014 Jun 19; 510(7505):393-6. PMID: 24870234.
      Citations: 168     Fields:    Translation:AnimalsCells
    54. Sun D, Luo M, Jeong M, Rodriguez B, Xia Z, Hannah R, Wang H, Le T, Faull KF, Chen R, Gu H, Bock C, Meissner A, Göttgens B, Darlington GJ, Li W, Goodell MA. Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal. Cell Stem Cell. 2014 May 01; 14(5):673-88. PMID: 24792119.
      Citations: 155     Fields:    Translation:AnimalsCells
    55. Sun D, Xi Y, Rodriguez B, Park HJ, Tong P, Meong M, Goodell MA, Li W. MOABS: model based analysis of bisulfite sequencing data. Genome Biol. 2014 Feb 24; 15(2):R38. PMID: 24565500.
      Citations: 69     Fields:    Translation:HumansCells
    56. Cullen SM, Mayle A, Rossi L, Goodell MA. Hematopoietic stem cell development: an epigenetic journey. Curr Top Dev Biol. 2014; 107:39-75. PMID: 24439802.
      Citations: 28     Fields:    Translation:HumansCells
    57. Jeong M, Sun D, Luo M, Huang Y, Challen GA, Rodriguez B, Zhang X, Chavez L, Wang H, Hannah R, Kim SB, Yang L, Ko M, Chen R, Göttgens B, Lee JS, Gunaratne P, Godley LA, Darlington GJ, Rao A, Li W, Goodell MA. Large conserved domains of low DNA methylation maintained by Dnmt3a. Nat Genet. 2014 Jan; 46(1):17-23. PMID: 24270360.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    58. Kim SJ, Zhao H, Hardikar S, Singh AK, Goodell MA, Chen T. A DNMT3A mutation common in AML exhibits dominant-negative effects in murine ES cells. Blood. 2013 Dec 12; 122(25):4086-9. PMID: 24167195.
      Citations: 75     Fields:    Translation:AnimalsCells
    59. Goodell MA. Parental permissions: H19 and keeping the stem cell progeny under control. Cell Stem Cell. 2013 Aug 01; 13(2):137-8. PMID: 23910078.
      Citations: 7     Fields:    Translation:AnimalsCells
    60. Shi FT, Kim H, Lu W, He Q, Liu D, Goodell MA, Wan M, Songyang Z. Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells. J Biol Chem. 2013 Jul 19; 288(29):20776-84. PMID: 23729667.
      Citations: 60     Fields:    Translation:AnimalsCells
    61. Cullen SM, Goodell MA. Rising from the crypt: decreasing DNA methylation during differentiation of the small intestine. Genome Biol. 2013 May 28; 14(5):116. PMID: 23714004.
      Citations:    Fields:    Translation:AnimalsCells
    62. Goodell MA, Godley LA. Perspectives and future directions for epigenetics in hematology. Blood. 2013 Jun 27; 121(26):5131-7. PMID: 23692857.
      Citations: 10     Fields:    Translation:Humans
    63. Kahle JJ, Souroullas GP, Yu P, Zohren F, Lee Y, Shaw CA, Zoghbi HY, Goodell MA. Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery. PLoS Genet. 2013 Mar; 9(3):e1003359. PMID: 23555280.
      Citations:    Fields:    Translation:AnimalsCells
    64. Ergen AV, Jeong M, Lin KK, Challen GA, Goodell MA. Isolation and characterization of mouse side population cells. Methods Mol Biol. 2013; 946:151-62. PMID: 23179831.
      Citations: 8     Fields:    Translation:AnimalsCells
    65. Rossi L, Lemoli RM, Goodell MA. Gpr171, a putative P2Y-like receptor, negatively regulates myeloid differentiation in murine hematopoietic progenitors. Exp Hematol. 2013 Jan; 41(1):102-12. PMID: 23022127.
      Citations: 8     Fields:    Translation:AnimalsCells
    66. Rossi L, Lin KK, Boles NC, Yang L, King KY, Jeong M, Mayle A, Goodell MA. Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice. Cell Stem Cell. 2012 Sep 07; 11(3):302-17. PMID: 22958929.
      Citations: 94     Fields:    Translation:AnimalsCells
    67. Zohren F, Souroullas GP, Luo M, Gerdemann U, Imperato MR, Wilson NK, Göttgens B, Lukov GL, Goodell MA. The transcription factor Lyl-1 regulates lymphoid specification and the maintenance of early T lineage progenitors. Nat Immunol. 2012 Jul 08; 13(8):761-9. PMID: 22772404.
      Citations: 18     Fields:    Translation:AnimalsCells
    68. Mayle A, Luo M, Jeong M, Goodell MA. Flow cytometry analysis of murine hematopoietic stem cells. Cytometry A. 2013 Jan; 83(1):27-37. PMID: 22736515.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    69. Li J, Harris RA, Cheung SW, Coarfa C, Jeong M, Goodell MA, White LD, Patel A, Kang SH, Shaw C, Chinault AC, Gambin T, Gambin A, Lupski JR, Milosavljevic A. Genomic hypomethylation in the human germline associates with selective structural mutability in the human genome. PLoS Genet. 2012; 8(5):e1002692. PMID: 22615578.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    70. James RA, Rao MM, Chen ES, Goodell MA, Shaw CA. The Hematopoietic Expression Viewer: expanding mobile apps as a scientific tool. Bioinformatics. 2012 Jul 15; 28(14):1941-2. PMID: 22576171.
      Citations: 4     Fields:    Translation:HumansCells
    71. Ergen AV, Boles NC, Goodell MA. Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing. Blood. 2012 Mar 15; 119(11):2500-9. PMID: 22289892.
      Citations: 70     Fields:    Translation:AnimalsCells
    72. Challen GA, Sun D, Jeong M, Luo M, Jelinek J, Berg JS, Bock C, Vasanthakumar A, Gu H, Xi Y, Liang S, Lu Y, Darlington GJ, Meissner A, Issa JP, Godley LA, Li W, Goodell MA. Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet. 2011 Dec 04; 44(1):23-31. PMID: 22138693.
      Citations: 348     Fields:    Translation:HumansAnimalsCells
    73. Berg JS, Lin KK, Sonnet C, Boles NC, Weksberg DC, Nguyen H, Holt LJ, Rickwood D, Daly RJ, Goodell MA. Imprinted genes that regulate early mammalian growth are coexpressed in somatic stem cells. PLoS One. 2011; 6(10):e26410. PMID: 22039481.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    74. Challen GA, Goodell MA. Bridge over troubled stem cells. Mol Ther. 2011 Oct; 19(10):1756-8. PMID: 21964307.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    75. Lin KK, Rossi L, Boles NC, Hall BE, George TC, Goodell MA. CD81 is essential for the re-entry of hematopoietic stem cells to quiescence following stress-induced proliferation via deactivation of the Akt pathway. PLoS Biol. 2011 Sep; 9(9):e1001148. PMID: 21931533.
      Citations: 16     Fields:    Translation:AnimalsCells
    76. King KY, Goodell MA. Inflammatory modulation of HSCs: viewing the HSC as a foundation for the immune response. Nat Rev Immunol. 2011 Sep 09; 11(10):685-92. PMID: 21904387.
      Citations: 162     Fields:    Translation:HumansAnimalsCells
    77. King KY, Baldridge MT, Weksberg DC, Chambers SM, Lukov GL, Wu S, Boles NC, Jung SY, Qin J, Liu D, Songyang Z, Eissa NT, Taylor GA, Goodell MA. Irgm1 protects hematopoietic stem cells by negative regulation of IFN signaling. Blood. 2011 Aug 11; 118(6):1525-33. PMID: 21633090.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    78. Souroullas GP, Goodell MA. A new allele of Lyl1 confirms its important role in hematopoietic stem cell function. Genesis. 2011 Jun; 49(6):441-8. PMID: 21387538.
      Citations: 2     Fields:    Translation:AnimalsCells
    79. Boles NC, Lin KK, Lukov GL, Bowman TV, Baldridge MT, Goodell MA. CD48 on hematopoietic progenitors regulates stem cells and suppresses tumor formation. Blood. 2011 Jul 07; 118(1):80-7. PMID: 21576698.
      Citations: 15     Fields:    Translation:AnimalsCells
    80. Rossi L, Ergen AV, Goodell MA. TIMP-1 deficiency subverts cell-cycle dynamics in murine long-term HSCs. Blood. 2011 Jun 16; 117(24):6479-88. PMID: 21521782.
      Citations: 6     Fields:    Translation:AnimalsCells
    81. Liao J, Hammerick KE, Challen GA, Goodell MA, Kasper FK, Mikos AG. Investigating the role of hematopoietic stem and progenitor cells in regulating the osteogenic differentiation of mesenchymal stem cells in vitro. J Orthop Res. 2011 Oct; 29(10):1544-53. PMID: 21495066.
      Citations: 12     Fields:    Translation:AnimalsCells
    82. King KY, Goodell MA. Direct conversion of skin cells into blood: alchemy or science? Mol Ther. 2011 Feb; 19(2):227-8. PMID: 21289635.
      Citations:    Fields:    Translation:HumansAnimalsCells
    83. King KY, Lew JD, Ha NP, Lin JS, Ma X, Graviss EA, Goodell MA. Polymorphic allele of human IRGM1 is associated with susceptibility to tuberculosis in African Americans. PLoS One. 2011 Jan 21; 6(1):e16317. PMID: 21283700.
      Citations: 30     Fields:    Translation:Humans
    84. Baldridge MT, King KY, Goodell MA. Inflammatory signals regulate hematopoietic stem cells. Trends Immunol. 2011 Feb; 32(2):57-65. PMID: 21233016.
      Citations: 131     Fields:    Translation:HumansAnimalsCells
    85. Rossi L, Challen GA, Sirin O, Lin KK, Goodell MA. Hematopoietic stem cell characterization and isolation. Methods Mol Biol. 2011; 750:47-59. PMID: 21618082.
      Citations: 16     Fields:    Translation:AnimalsCells
    86. Sirin O, Lukov GL, Mao R, Conneely OM, Goodell MA. The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic stem cells. Nat Cell Biol. 2010 Dec; 12(12):1213-9. PMID: 21076412.
      Citations: 43     Fields:    Translation:AnimalsCells
    87. Lukov GL, Goodell MA. LYL1 degradation by the proteasome is directed by a N-terminal PEST rich site in a phosphorylation-independent manner. PLoS One. 2010 Sep 10; 5(9). PMID: 20844761.
      Citations: 3     Fields:    Translation:HumansCells
    88. Lukov GL, Rossi L, Souroullas GP, Mao R, Goodell MA. The expansion of T-cells and hematopoietic progenitors as a result of overexpression of the lymphoblastic leukemia gene, Lyl1 can support leukemia formation. Leuk Res. 2011 Mar; 35(3):405-12. PMID: 20705338.
      Citations: 3     Fields:    Translation:AnimalsCells
    89. Baldridge MT, King KY, Boles NC, Weksberg DC, Goodell MA. Quiescent haematopoietic stem cells are activated by IFN-gamma in response to chronic infection. Nature. 2010 Jun 10; 465(7299):793-7. PMID: 20535209.
      Citations: 285     Fields:    Translation:AnimalsCells
    90. Challen GA, Boles NC, Chambers SM, Goodell MA. Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell. 2010 Mar 05; 6(3):265-78. PMID: 20207229.
      Citations: 216     Fields:    Translation:AnimalsCells
    91. Challen GA, Goodell MA. Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells. Exp Hematol. 2010 May; 38(5):403-16. PMID: 20206228.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    92. Boles NC, Peddibhotla S, Chen AJ, Goodell MA, Rosen JM. Chk1 haploinsufficiency results in anemia and defective erythropoiesis. PLoS One. 2010 Jan 05; 5(1):e8581. PMID: 20052416.
      Citations: 13     Fields:    Translation:HumansAnimals
    93. Ergen AV, Goodell MA. Mechanisms of hematopoietic stem cell aging. Exp Gerontol. 2010 Apr; 45(4):286-90. PMID: 20034552.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    94. Sharabi AB, Lee SH, Goodell MA, Huang XF, Chen SY. Enhanced generation of myeloid lineages in hematopoietic differentiation from embryonic stem cells by silencing transcriptional repressor Twist-2. . 2009 Dec; 11(4):523-33. PMID: 20025523.
      Citations:    
    95. Foster AE, Okur FV, Biagi E, Lu A, Dotti G, Yvon E, Savoldo B, Carrum G, Andreeff M, Goodell MA, Heslop HE, Brenner MK. Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression. Mol Cancer. 2009 Nov 18; 8:106. PMID: 19922650.
      Citations: 3     Fields:    Translation:HumansCells
    96. Vieyra DS, Rosen A, Goodell MA. Identification and characterization of side population cells in embryonic stem cell cultures. Stem Cells Dev. 2009 Oct; 18(8):1155-66. PMID: 19113897.
      Citations: 9     Fields:    Translation:AnimalsCells
    97. Souroullas GP, Salmon JM, Sablitzky F, Curtis DJ, Goodell MA. Adult hematopoietic stem and progenitor cells require either Lyl1 or Scl for survival. Cell Stem Cell. 2009 Feb 06; 4(2):180-6. PMID: 19200805.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    98. Challen GA, Boles N, Lin KK, Goodell MA. Mouse hematopoietic stem cell identification and analysis. Cytometry A. 2009 Jan; 75(1):14-24. PMID: 19023891.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    99. Challen GA, Goodell MA. Promiscuous expression of H2B-GFP transgene in hematopoietic stem cells. PLoS One. 2008 Jun 04; 3(6):e2357. PMID: 18523660.
      Citations: 11     Fields:    Translation:AnimalsCells
    100. Feng CG, Weksberg DC, Taylor GA, Sher A, Goodell MA. The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation. Cell Stem Cell. 2008 Jan 10; 2(1):83-9. PMID: 18371424.
      Citations: 65     Fields:    Translation:AnimalsCells
    101. Weksberg DC, Chambers SM, Boles NC, Goodell MA. CD150- side population cells represent a functionally distinct population of long-term hematopoietic stem cells. Blood. 2008 Feb 15; 111(4):2444-51. PMID: 18055867.
      Citations: 61     Fields:    Translation:AnimalsCells
    102. Chambers SM, Boles NC, Lin KY, Tierney MP, Bowman TV, Bradfute SB, Chen AJ, Merchant AA, Sirin O, Weksberg DC, Merchant MG, Fisk CJ, Shaw CA, Goodell MA. Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem Cell. 2007 Nov; 1(5):578-91. PMID: 18371395.
      Citations: 161     Fields:    Translation:AnimalsCells
    103. Yankelevich M, Goodell MA, Kaplan J. Efficacy of delayed administration of post-chemotherapy granulocyte colony-stimulating factor: evidence from murine studies of bone marrow cell kinetics. Exp Hematol. 2008 Jan; 36(1):9-16. PMID: 17949891.
      Citations: 7     Fields:    Translation:AnimalsCells
    104. Berg JS, Goodell MA. An argument against a role for Oct4 in somatic stem cells. Cell Stem Cell. 2007 Oct 11; 1(4):359-60. PMID: 18371372.
      Citations: 18     Fields:    Translation:AnimalsCells
    105. Chambers SM, Shaw CA, Gatza C, Fisk CJ, Donehower LA, Goodell MA. Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation. PLoS Biol. 2007 Aug; 5(8):e201. PMID: 17676974.
      Citations: 283     Fields:    Translation:HumansAnimalsCells
    106. Vieyra DS, Goodell MA. Pluripotentiality and conditional transgene regulation in human embryonic stem cells expressing insulated tetracycline-ON transactivator. Stem Cells. 2007 Oct; 25(10):2559-66. PMID: 17628023.
      Citations: 16     Fields:    Translation:HumansCells
    107. Jolicoeur EM, Granger CB, Fakunding JL, Mockrin SC, Grant SM, Ellis SG, Weisel RD, Goodell MA. Bringing cardiovascular cell-based therapy to clinical application: perspectives based on a National Heart, Lung, and Blood Institute Cell Therapy Working Group meeting. Am Heart J. 2007 May; 153(5):732-42. PMID: 17452146.
      Citations: 4     Fields:    Translation:HumansAnimals
    108. Bowman TV, Merchant AA, Goodell MA. Molecular profiling of hematopoietic stem cells. Methods Mol Med. 2007; 134:1-16. PMID: 17666739.
      Citations: 5     Fields:    Translation:AnimalsCells
    109. Kustikova OS, Geiger H, Li Z, Brugman MH, Chambers SM, Shaw CA, Pike-Overzet K, de Ridder D, Staal FJ, von Keudell G, Cornils K, Nattamai KJ, Modlich U, Wagemaker G, Goodell MA, Fehse B, Baum C. Retroviral vector insertion sites associated with dominant hematopoietic clones mark "stemness" pathways. Blood. 2007 Mar 01; 109(5):1897-907. PMID: 17119121.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    110. Dumble M, Moore L, Chambers SM, Geiger H, Van Zant G, Goodell MA, Donehower LA. The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging. Blood. 2007 Feb 15; 109(4):1736-42. PMID: 17032926.
      Citations: 101     Fields:    Translation:AnimalsCells
    111. Ramos CA, Bowman TA, Boles NC, Merchant AA, Zheng Y, Parra I, Fuqua SA, Shaw CA, Goodell MA. Evidence for diversity in transcriptional profiles of single hematopoietic stem cells. PLoS Genet. 2006 Sep 29; 2(9):e159. PMID: 17009876.
      Citations: 28     Fields:    Translation:AnimalsCells
    112. Civin CI, Gewirtz AM, Goodell MA, Hawley RG, Murphy MJ. Editorial retraction. Stem Cells. 2006 Apr; 24(4):804. PMID: 16582451.
      Citations:    Fields:    
    113. Lin KK, Goodell MA. Purification of hematopoietic stem cells using the side population. Methods Enzymol. 2006; 420:255-64. PMID: 17161700.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    114. Bowman TV, McCooey AJ, Merchant AA, Ramos CA, Fonseca P, Poindexter A, Bradfute SB, Oliveira DM, Green R, Zheng Y, Jackson KA, Chambers SM, McKinney-Freeman SL, Norwood KG, Darlington G, Gunaratne PH, Steffen D, Goodell MA. Differential mRNA processing in hematopoietic stem cells. Stem Cells. 2006 Mar; 24(3):662-70. PMID: 16373690.
      Citations: 5     Fields:    Translation:AnimalsCells
    115. Goodell MA. Stem cell identification and sorting using the Hoechst 33342 side population (SP). Curr Protoc Cytom. 2005 Nov; Chapter 9:Unit9.18. PMID: 18770827.
      Citations: 25     Fields:    Translation:AnimalsCells
    116. Camargo FD, Chambers SM, Drew E, McNagny KM, Goodell MA. Hematopoietic stem cells do not engraft with absolute efficiencies. Blood. 2006 Jan 15; 107(2):501-7. PMID: 16204316.
      Citations: 40     Fields:    Translation:AnimalsCells
    117. Bradfute SB, Graubert TA, Goodell MA. Roles of Sca-1 in hematopoietic stem/progenitor cell function. Exp Hematol. 2005 Jul; 33(7):836-43. PMID: 15963860.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    118. Vieyra DS, Jackson KA, Goodell MA. Plasticity and tissue regenerative potential of bone marrow-derived cells. Stem Cell Rev. 2005; 1(1):65-9. PMID: 17132877.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    119. Civin CI, Gewirtz AM, Hawley RG, Goodell MA. Advancing the fast-paced field of stem cell research: stem cells increases from 6 to 10 issues in its 23rd year of publication. Stem Cells. 2005; 23(1):1-2. PMID: 15625117.
      Citations:    Fields:    Translation:HumansAnimalsCells
    120. Goodell MA, McKinney-Freeman S, Camargo FD. Isolation and characterization of side population cells. Methods Mol Biol. 2005; 290:343-52. PMID: 15361673.
      Citations: 30     Fields:    Translation:AnimalsCells
    121. Venezia TA, Merchant AA, Ramos CA, Whitehouse NL, Young AS, Shaw CA, Goodell MA. Molecular signatures of proliferation and quiescence in hematopoietic stem cells. PLoS Biol. 2004 Oct; 2(10):e301. PMID: 15459755.
      Citations: 147     Fields:    Translation:HumansAnimalsCells
    122. McKinney-Freeman S, Goodell MA. Circulating hematopoietic stem cells do not efficiently home to bone marrow during homeostasis. Exp Hematol. 2004 Sep; 32(9):868-76. PMID: 15345289.
      Citations: 9     Fields:    Translation:AnimalsCells
    123. Qyang Y, Chambers SM, Wang P, Xia X, Chen X, Goodell MA, Zheng H. Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage. Biochemistry. 2004 May 11; 43(18):5352-9. PMID: 15122901.
      Citations: 22     Fields:    Translation:AnimalsCells
    124. Camargo FD, Finegold M, Goodell MA. Hematopoietic myelomonocytic cells are the major source of hepatocyte fusion partners. J Clin Invest. 2004 May; 113(9):1266-70. PMID: 15124017.
      Citations: 67     Fields:    Translation:AnimalsCells
    125. Snyder EY, Daley GQ, Goodell M. Taking stock and planning for the next decade: realistic prospects for stem cell therapies for the nervous system. J Neurosci Res. 2004 Apr 15; 76(2):157-68. PMID: 15048913.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    126. Norwood K, Wang RY, Hirschmann-Jax C, Andreeff M, Brenner MK, Goodell MA, Wulf GG. An in vivo propagated human acute myeloid leukemia expressing ABCA3. Leuk Res. 2004 Mar; 28(3):295-9. PMID: 14687625.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    127. Jackson KA, Snyder DS, Goodell MA. Skeletal muscle fiber-specific green autofluorescence: potential for stem cell engraftment artifacts. Stem Cells. 2004; 22(2):180-7. PMID: 14990857.
      Citations: 35     Fields:    Translation:AnimalsCells
    128. Olmsted-Davis EA, Gugala Z, Camargo F, Gannon FH, Jackson K, Kienstra KA, Shine HD, Lindsey RW, Hirschi KK, Goodell MA, Brenner MK, Davis AR. Primitive adult hematopoietic stem cells can function as osteoblast precursors. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15877-82. PMID: 14673088.
      Citations: 42     Fields:    Translation:AnimalsCells
    129. Camargo FD, Green R, Capetanaki Y, Jackson KA, Goodell MA, Capetenaki Y. Single hematopoietic stem cells generate skeletal muscle through myeloid intermediates. Nat Med. 2003 Dec; 9(12):1520-7. PMID: 14625546.
      Citations: 107     Fields:    Translation:AnimalsCells
    130. Welm B, Behbod F, Goodell MA, Rosen JM. Isolation and characterization of functional mammary gland stem cells. Cell Prolif. 2003 Oct; 36 Suppl 1:17-32. PMID: 14521513.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    131. McKinney-Freeman SL, Majka SM, Jackson KA, Norwood K, Hirschi KK, Goodell MA. Altered phenotype and reduced function of muscle-derived hematopoietic stem cells. Exp Hematol. 2003 Sep; 31(9):806-14. PMID: 12962727.
      Citations: 9     Fields:    Translation:AnimalsCells
    132. Oliveira DM, Goodell MA. Transient RNA interference in hematopoietic progenitors with functional consequences. Genesis. 2003 Aug; 36(4):203-8. PMID: 12929091.
      Citations: 11     Fields:    Translation:AnimalsCells
    133. Nadin BM, Goodell MA, Hirschi KK. Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood. 2003 Oct 01; 102(7):2436-43. PMID: 12805065.
      Citations: 25     Fields:    Translation:AnimalsCells
    134. Brenner MK, Wulf GG, Rill DR, Luo KL, Goodell MA, Mei Z, Kuehnle I, Brown MP, Pule M, Heslop HE, Krance RA. Complement-fixing CD45 monoclonal antibodies to facilitate stem cell transplantation in mouse and man. Ann N Y Acad Sci. 2003 May; 996:80-8. PMID: 12799286.
      Citations: 7     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    135. Wulf GG, Luo KL, Jackson KA, Brenner MK, Goodell MA. Cells of the hepatic side population contribute to liver regeneration and can be replenished with bone marrow stem cells. Haematologica. 2003 Apr; 88(4):368-78. PMID: 12681963.
      Citations: 38     Fields:    Translation:AnimalsCells
    136. Bradfute SB, Goodell MA. Adenoviral transduction of mouse hematopoietic stem cells. Mol Ther. 2003 Mar; 7(3):334-40. PMID: 12668129.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    137. Ramos CA, Venezia TA, Camargo FA, Goodell MA. Techniques for the study of adult stem cells: be fruitful and multiply. Biotechniques. 2003 Mar; 34(3):572-8, 580-4, 586-91. PMID: 12661162.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    138. Majka SM, Jackson KA, Kienstra KA, Majesky MW, Goodell MA, Hirschi KK. Distinct progenitor populations in skeletal muscle are bone marrow derived and exhibit different cell fates during vascular regeneration. J Clin Invest. 2003 Jan; 111(1):71-9. PMID: 12511590.
      Citations: 57     Fields:    Translation:AnimalsCells
    139. Ramos CA, Zheng Y, Colombowala I, Goodell MA. Tracing the origin of non-hematopoietic cells using CD45 PCR restriction fragment length polymorphisms. Biotechniques. 2003 Jan; 34(1):160-2. PMID: 12545553.
      Citations: 1     Fields:    Translation:AnimalsCells
    140. Daley GQ, Goodell MA, Snyder EY. Realistic prospects for stem cell therapeutics. Hematology Am Soc Hematol Educ Program. 2003; 398-418. PMID: 14633792.
      Citations: 19     Fields:    Translation:HumansCells
    141. Wulf GG, Luo KL, Goodell MA, Brenner MK. Anti-CD45-mediated cytoreduction to facilitate allogeneic stem cell transplantation. Blood. 2003 Mar 15; 101(6):2434-9. PMID: 12433683.
      Citations: 12     Fields:    Translation:AnimalsCells
    142. Castro RF, Jackson KA, Goodell MA, Robertson CS, Liu H, Shine HD. Failure of bone marrow cells to transdifferentiate into neural cells in vivo. Science. 2002 Aug 23; 297(5585):1299. PMID: 12193778.
      Citations: 82     Fields:    Translation:AnimalsCells
    143. Kuehnle I, Goodell MA. The therapeutic potential of stem cells from adults. BMJ. 2002 Aug 17; 325(7360):372-6. PMID: 12183311.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    144. Heinz M, Huang CA, Emery DW, Giovino MA, LeGuern A, Kurilla-Mahon B, Theodore P, Arn JS, Sykes M, Mulligan R, Down JD, Sachs DH, Goodell MA. Use of CD9 expression to enrich for porcine hematopoietic progenitors. Exp Hematol. 2002 Jul; 30(7):809-15. PMID: 12135680.
      Citations: 5     Fields:    Translation:AnimalsCells
    145. Welm BE, Tepera SB, Venezia T, Graubert TA, Rosen JM, Goodell MA. Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol. 2002 May 01; 245(1):42-56. PMID: 11969254.
      Citations: 183     Fields:    Translation:AnimalsCells
    146. McKinney-Freeman SL, Jackson KA, Camargo FD, Ferrari G, Mavilio F, Goodell MA. Muscle-derived hematopoietic stem cells are hematopoietic in origin. Proc Natl Acad Sci U S A. 2002 Feb 05; 99(3):1341-6. PMID: 11830662.
      Citations: 74     Fields:    Translation:AnimalsCells
    147. Jackson KA, Majka SM, Wulf GG, Goodell MA. Stem cells: a minireview. J Cell Biochem Suppl. 2002; 38:1-6. PMID: 12046843.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
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