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InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
DivisionMolecular & Cellular Biology
AddressOne Baylor Plaza
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, Mo Q, Edwards DP, Huang S, Xin L, Xu J, Li Y, Lewis MT, Wang T, Westbrook TF, Rosen JM, Zhang XH. Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 2016 Jun; 18(6):632-44. PMID: 27183469; PMCID: PMC4884142 [Available on 12/01/16].
    2. Niu W, Shen G, Yuan Y, Ma X, Li S, Wang J, Fan Z, Liao L. Biodegradable PTLGA Terpolymers versus Collagen Implants Used as an Adjuvant in Trabeculectomy in Rabbit Eye. J Ophthalmol. 2015; 2015:737198. PMID: 26697212.
      View in: PubMed
    3. Liu Z, Oyola MG, Zhou S, Chen X, Liao L, Tien JC, Mani SK, Xu J. Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors. Int J Biol Sci. 2015; 11(12):1447-57. PMID: 26681924.
      View in: PubMed
    4. Qin L, Xu Y, Xu Y, Ma G, Liao L, Wu Y, Li Y, Wang X, Wang X, Jiang J, Wang J, Xu J. NCOA1 promotes angiogenesis in breast tumors by simultaneously enhancing both HIF1a- and AP-1-mediated VEGFa transcription. Oncotarget. 2015 Sep 15; 6(27):23890-904. PMID: 26287601.
      View in: PubMed
    5. Wang L, Yu Y, Chow DC, Yan F, Hsu CC, Stossi F, Mancini MA, Palzkill T, Liao L, Zhou S, Xu J, Lonard DM, O'Malley BW. Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10; 28(2):240-52. PMID: 26267537.
      View in: PubMed
    6. Chen X, Qin L, Liu Z, Liao L, Martin JF, Xu J. Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype. Int J Biol Sci. 2015; 11(9):1056-72. PMID: 26221073.
      View in: PubMed
    7. Scoville DW, Cyphert HA, Liao L, Xu J, Reynolds A, Guo S, Stein R. MLL3 and MLL4 Methyltransferases Bind to the MAFA and MAFB Transcription Factors to Regulate Islet ?-Cell Function. Diabetes. 2015 Nov; 64(11):3772-83. PMID: 26180087.
      View in: PubMed
    8. Liu Z, Chen X, Zhou S, Liao L, Jiang R, Xu J. The histone H3K9 demethylase Kdm3b is required for somatic growth and female reproductive function. Int J Biol Sci. 2015; 11(5):494-507. PMID: 25892958; PMCID: PMC4400382.
    9. Tien JC, Liao L, Liu Y, Liu Z, Lee DK, Wang F, Xu J. The steroid receptor coactivator-3 is required for developing neuroendocrine tumor in the mouse prostate. Int J Biol Sci. 2014; 10(10):1116-27. PMID: 25332686; PMCID: PMC4202028.
    10. Lee DK, Liu Y, Liao L, Wang F, Xu J. The prostate basal cell (BC) heterogeneity and the p63-positive BC differentiation spectrum in mice. Int J Biol Sci. 2014; 10(9):1007-17. PMID: 25210499; PMCID: PMC4159692.
    11. Qin L, Wu YL, Toneff MJ, Li D, Liao L, Gao X, Bane FT, Tien JC, Xu Y, Feng Z, Yang Z, Xu Y, Theissen SM, Li Y, Young L, Xu J. NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis. Cancer Res. 2014 Jul 1; 74(13):3477-88. PMID: 24769444; PMCID: PMC4083628.
    12. Xu Y, Xu Y, Liao L, Zhou N, Theissen SM, Liao XH, Nguyen H, Ludwig T, Qin L, Martinez JD, Jiang J, Xu J. Inducible knockout of Twist1 in young and adult mice prolongs hair growth cycle and has mild effects on general health, supporting Twist1 as a preferential cancer target. Am J Pathol. 2013 Oct; 183(4):1281-92. PMID: 23906809; PMCID: PMC3791869.
    13. Tien JC, Liu Z, Liao L, Wang F, Xu Y, Wu YL, Zhou N, Ittmann M, Xu J. The steroid receptor coactivator-3 is required for the development of castration-resistant prostate cancer. Cancer Res. 2013 Jul 1; 73(13):3997-4008. PMID: 23650284; PMCID: PMC3732785.
    14. Zhu L, Yang Y, Xu P, Zou F, Yan X, Liao L, Xu J, O'Malley BW, Xu Y. Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice. Endocrinology. 2013 Jan; 154(1):150-8. PMID: 23211707; PMCID: PMC3529365.
    15. Kawagoe J, Li Q, Mussi P, Liao L, Lydon JP, DeMayo FJ, Xu J. Nuclear receptor coactivator-6 attenuates uterine estrogen sensitivity to permit embryo implantation. Dev Cell. 2012 Oct 16; 23(4):858-65. PMID: 23079602; PMCID: PMC3479668.
    16. Park S, Yoon S, Zhao Y, Park SE, Liao L, Xu J, Lydon JP, DeMayo FJ, O'Malley BW, Bagchi MK, Katzenellenbogen BS. Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA. Endocrinology. 2012 Aug; 153(8):3982-94. PMID: 22585830; PMCID: PMC3404350.
    17. Dearth RK, Kuiatse I, Wang YF, Liao L, Hilsenbeck SG, Brown PH, Xu J, Lee AV. A moderate elevation of circulating levels of IGF-I does not alter ErbB2 induced mammary tumorigenesis. BMC Cancer. 2011; 11:377. PMID: 21867536; PMCID: PMC3189189.
    18. Park S, Zhao Y, Yoon S, Xu J, Liao L, Lydon J, DeMayo F, O'Malley BW, Katzenellenbogen BS. Repressor of estrogen receptor activity (REA) is essential for mammary gland morphogenesis and functional activities: studies in conditional knockout mice. Endocrinology. 2011 Nov; 152(11):4336-49. PMID: 21862609; PMCID: PMC3199013.
    19. Zerrad-Saadi A, Lambert-Blot M, Mitchell C, Bretes H, Collin de l'Hortet A, Baud V, Chereau F, Sotiropoulos A, Kopchick JJ, Liao L, Xu J, Gilgenkrantz H, Guidotti JE. GH receptor plays a major role in liver regeneration through the control of EGFR and ERK1/2 activation. Endocrinology. 2011 Jul; 152(7):2731-41. PMID: 21540290.
      View in: PubMed
    20. Hong J, Zhou J, Fu J, He T, Qin J, Wang L, Liao L, Xu J. Phosphorylation of serine 68 of Twist1 by MAPKs stabilizes Twist1 protein and promotes breast cancer cell invasiveness. Cancer Res. 2011 Jun 1; 71(11):3980-90. PMID: 21502402; PMCID: PMC3107354.
    21. Qin L, Chen X, Wu Y, Feng Z, He T, Wang L, Liao L, Xu J. Steroid receptor coactivator-1 upregulates integrin ?? expression to promote breast cancer cell adhesion and migration. Cancer Res. 2011 Mar 1; 71(5):1742-51. PMID: 21343398; PMCID: PMC3076137.
    22. Fu J, Qin L, He T, Qin J, Hong J, Wong J, Liao L, Xu J. The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasis. Cell Res. 2011 Feb; 21(2):275-89. PMID: 20714342; PMCID: PMC3193433.
    23. Liu Z, Zhou S, Liao L, Chen X, Meistrich M, Xu J. Jmjd1a demethylase-regulated histone modification is essential for cAMP-response element modulator-regulated gene expression and spermatogenesis. J Biol Chem. 2010 Jan 22; 285(4):2758-70. PMID: 19910458; PMCID: PMC2807331.
    24. Li X, Liao L, Yan X, Huang G, Lin J, Lei M, Wang X, Zhou Z. Protective effects of 1-alpha-hydroxyvitamin D3 on residual beta-cell function in patients with adult-onset latent autoimmune diabetes (LADA). Diabetes Metab Res Rev. 2009 Jul; 25(5):411-6. PMID: 19488999.
      View in: PubMed
    25. Xu J, Liao L, Qin J, Xu J, Liu D, Songyang Z. Identification of Flightless-I as a substrate of the cytokine-independent survival kinase CISK. J Biol Chem. 2009 May 22; 284(21):14377-85. PMID: 19293151; PMCID: PMC2682886.
    26. Wang S, Yuan Y, Liao L, Kuang SQ, Tien JC, O'Malley BW, Xu J. Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proc Natl Acad Sci U S A. 2009 Jan 6; 106(1):151-6. PMID: 19109434; PMCID: PMC2629242.
    27. Liu Z, Liao L, Zhou S, Xu J. Generation and validation of a mouse line with a floxed SRC-3/AIB1 allele for conditional knockout. Int J Biol Sci. 2008; 4(4):202-7. PMID: 18690289; PMCID: PMC2491728.
    28. Qin L, Liao L, Redmond A, Young L, Yuan Y, Chen H, O'Malley BW, Xu J. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol Cell Biol. 2008 Oct; 28(19):5937-50. PMID: 18644862; PMCID: PMC2547002.
    29. Liao L, Chen X, Wang S, Parlow AF, Xu J. Steroid receptor coactivator 3 maintains circulating insulin-like growth factor I (IGF-I) by controlling IGF-binding protein 3 expression. Mol Cell Biol. 2008 Apr; 28(7):2460-9. PMID: 18212051; PMCID: PMC2268437.
    30. Xia J, Liao L, Sarkar J, Matsumoto K, Reddy JK, Xu J, Kemper B. Redundant enhancement of mouse constitutive androstane receptor transactivation by p160 coactivator family members. Arch Biochem Biophys. 2007 Dec 1; 468(1):49-57. PMID: 17950690; PMCID: PMC2151205.
    31. Chung AC, Zhou S, Liao L, Tien JC, Greenberg NM, Xu J. Genetic ablation of the amplified-in-breast cancer 1 inhibits spontaneous prostate cancer progression in mice. Cancer Res. 2007 Jun 15; 67(12):5965-75. PMID: 17575167; PMCID: PMC2898573.
    32. Mussi P, Liao L, Park SE, Ciana P, Maggi A, Katzenellenbogen BS, Xu J, O'Malley BW. Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland. Proc Natl Acad Sci U S A. 2006 Nov 7; 103(45):16716-21. PMID: 17065319; PMCID: PMC1636521.
    33. Liao L, Dearth RK, Zhou S, Britton OL, Lee AV, Xu J. Liver-specific overexpression of the insulin-like growth factor-I enhances somatic growth and partially prevents the effects of growth hormone deficiency. Endocrinology. 2006 Aug; 147(8):3877-88. PMID: 16709615.
      View in: PubMed
    34. Kuang SQ, Liao L, Wang S, Medina D, O'Malley BW, Xu J. Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Res. 2005 Sep 1; 65(17):7993-8002. PMID: 16140972.
      View in: PubMed
    35. Park SE, Xu J, Frolova A, Liao L, O'Malley BW, Katzenellenbogen BS. Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo. Mol Cell Biol. 2005 Mar; 25(5):1989-99. PMID: 15713652; PMCID: PMC549370.
    36. Zhang H, Kuang SQ, Liao L, Zhou S, Xu J. Haploid inactivation of the amplified-in-breast cancer 3 coactivator reduces the inhibitory effect of peroxisome proliferator-activated receptor gamma and retinoid X receptor on cell proliferation and accelerates polyoma middle-T antigen-induced mammary tumorigenesis in mice. Cancer Res. 2004 Oct 1; 64(19):7169-77. PMID: 15466215.
      View in: PubMed
    37. Mark M, Yoshida-Komiya H, Gehin M, Liao L, Tsai MJ, O'Malley BW, Chambon P, Xu J. Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4453-8. PMID: 15070739; PMCID: PMC384768.
    38. Kuang SQ, Liao L, Zhang H, Lee AV, O'Malley BW, Xu J. AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice. Cancer Res. 2004 Mar 1; 64(5):1875-85. PMID: 14996752.
      View in: PubMed
    39. Zhang H, Liao L, Kuang SQ, Xu J. Spatial distribution of the messenger ribonucleic acid and protein of the nuclear receptor coactivator, amplified in breast cancer-3, in mice. Endocrinology. 2003 Apr; 144(4):1435-43. PMID: 12639927.
      View in: PubMed
    40. Nishihara E, Yoshida-Komiya H, Chan CS, Liao L, Davis RL, O'Malley BW, Xu J. SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells. J Neurosci. 2003 Jan 1; 23(1):213-22. PMID: 12514218.
      View in: PubMed
    41. Liao L, Kuang SQ, Yuan Y, Gonzalez SM, O'Malley BW, Xu J. Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. J Steroid Biochem Mol Biol. 2002 Dec; 83(1-5):3-14. PMID: 12650696.
      View in: PubMed
    42. Kuang SQ, Liao L, Zhang H, Pereira FA, Yuan Y, DeMayo FJ, Ko L, Xu J. Deletion of the cancer-amplified coactivator AIB3 results in defective placentation and embryonic lethality. J Biol Chem. 2002 Nov 22; 277(47):45356-60. PMID: 12368298.
      View in: PubMed
    43. Liao L, Kuang SQ, Yuan YH, Xu JM. A rapid and cost-effective screening method for identification of targeted embryonic stem cells. Shi Yan Sheng Wu Xue Bao. 2002 Sep; 35(3):163-8. PMID: 15344375.
      View in: PubMed
    44. Yuan Y, Liao L, Tulis DA, Xu J. Steroid receptor coactivator-3 is required for inhibition of neointima formation by estrogen. Circulation. 2002 Jun 4; 105(22):2653-9. PMID: 12045172.
      View in: PubMed
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