TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
Address2450 HOLCOMBE
Houston, TX 77021
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Space Medicine
    DivisionCenter for Space Medicine

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Xu J, Wang Y, Kauffman AE, Zhang Y, Li Y, Zhu J, Maratea K, Fabre K, Zhang Q, Woodruff TK, Xiao S. A Tiered Female Ovarian Toxicity Screening Identifies Toxic Effects of Checkpoint Kinase 1 Inhibitors on Murine Growing Follicles. Toxicol Sci. 2020 Oct 01; 177(2):405-419. PMID: 32697846.
      Citations:    Fields:    
    2. Fabre K, Berridge B, Proctor WR, Ralston S, Will Y, Baran SW, Yoder G, Van Vleet TR. Introduction to a manuscript series on the characterization and use of microphysiological systems (MPS) in pharmaceutical safety and ADME applications. Lab Chip. 2020 03 17; 20(6):1049-1057. PMID: 32073020.
      Citations: 2     Fields:    
    3. Hardwick RN, Betts CJ, Whritenour J, Sura R, Thamsen M, Kaufman EH, Fabre K. Drug-induced skin toxicity: gaps in preclinical testing cascade as opportunities for complex in vitro models and assays. Lab Chip. 2020 01 21; 20(2):199-214. PMID: 31598618.
      Citations:    Fields:    
    4. McAleer CW, Pointon A, Long CJ, Brighton RL, Wilkin BD, Bridges LR, Narasimhan Sriram N, Fabre K, McDougall R, Muse VP, Mettetal JT, Srivastava A, Williams D, Schnepper MT, Roles JL, Shuler ML, Hickman JJ, Ewart L. On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships. Sci Rep. 2019 07 03; 9(1):9619. PMID: 31270362.
      Citations: 8     Fields:    Translation:Humans
    5. Fabre KM, Delsing L, Hicks R, Colclough N, Crowther DC, Ewart L. Utilizing microphysiological systems and induced pluripotent stem cells for disease modeling: a case study for blood brain barrier research in a pharmaceutical setting. Adv Drug Deliv Rev. 2019 02 01; 140:129-135. PMID: 30253201.
      Citations:    Fields:    Translation:HumansAnimalsCells
    6. Cook JA, Naz S, Anver MR, Sowers AL, Fabre K, Krishna MC, Mitchell JB. Cancer Incidence in C3H Mice Protected from Lethal Total-Body Radiation after Amifostine. Radiat Res. 2018 05; 189(5):490-496. PMID: 29528769.
      Citations: 2     Fields:    Translation:Animals
    7. Ewart L, Dehne EM, Fabre K, Gibbs S, Hickman J, Hornberg E, Ingelman-Sundberg M, Jang KJ, Jones DR, Lauschke VM, Marx U, Mettetal JT, Pointon A, Williams D, Zimmermann WH, Newham P. Application of Microphysiological Systems to Enhance Safety Assessment in Drug Discovery. Annu Rev Pharmacol Toxicol. 2018 01 06; 58:65-82. PMID: 29029591.
      Citations: 15     Fields:    Translation:HumansAnimals
    8. Ewart L, Fabre K, Chakilam A, Dragan Y, Duignan DB, Eswaraka J, Gan J, Guzzie-Peck P, Otieno M, Jeong CG, Keller DA, de Morais SM, Phillips JA, Proctor W, Sura R, Van Vleet T, Watson D, Will Y, Tagle D, Berridge B. Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective. Exp Biol Med (Maywood). 2017 10; 242(16):1579-1585. PMID: 28622731.
      Citations: 12     Fields:    Translation:Humans
    9. Livingston CA, Fabre KM, Tagle DA. Facilitating the commercialization and use of organ platforms generated by the microphysiological systems (Tissue Chip) program through public-private partnerships. Comput Struct Biotechnol J. 2016; 14:207-210. PMID: 27904714.
    10. Fabre KM, Livingston C, Tagle DA. Organs-on-chips (microphysiological systems): tools to expedite efficacy and toxicity testing in human tissue. Exp Biol Med (Maywood). 2014 Sep; 239(9):1073-7. PMID: 24962171.
      Citations: 24     Fields:    Translation:HumansAnimals
    11. Sutherland ML, Fabre KM, Tagle DA. The National Institutes of Health Microphysiological Systems Program focuses on a critical challenge in the drug discovery pipeline. Stem Cell Res Ther. 2013; 4 Suppl 1:I1. PMID: 24565163.
      Citations: 24     Fields:    Translation:HumansAnimals
    12. Li F, Jiang C, Krausz KW, Li Y, Albert I, Hao H, Fabre KM, Mitchell JB, Patterson AD, Gonzalez FJ. Microbiome remodelling leads to inhibition of intestinal farnesoid X receptor signalling and decreased obesity. Nat Commun. 2013; 4:2384. PMID: 24064762.
      Citations: 148     Fields:    Translation:AnimalsCells
    13. Fabre KM, Saito K, DeGraff W, Sowers AL, Thetford A, Cook JA, Krishna MC, Mitchell JB. The effects of resveratrol and selected metabolites on the radiation and antioxidant response. . 2011 Nov 15; 12(10):915-23. PMID: 22024758.
    14. Fabre KM, Ramaiah L, Dregalla RC, Desaintes C, Weil MM, Bailey SM, Ullrich RL. Murine Prkdc polymorphisms impact DNA-PKcs function. Radiat Res. 2011 Apr; 175(4):493-500. PMID: 21265624.
      Citations: 6     Fields:    Translation:AnimalsCells
    15. Mitchell JB, Choudhuri R, Fabre K, Sowers AL, Citrin D, Zabludoff SD, Cook JA. In vitro and in vivo radiation sensitization of human tumor cells by a novel checkpoint kinase inhibitor, AZD7762. Clin Cancer Res. 2010 Apr 01; 16(7):2076-84. PMID: 20233881.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
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