Loading...
Header Logo
Keywords
Last Name
Institution

KOEN J. T. VENKEN

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Biochemistry & Molecular Biology
DivisionBiochemistry & Molecular Biology
vCardDownload vCard
    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pharmacology and Chemical Biology
    DivisionPharmacology


    Collapse ORNG Applications 
    Collapse Verify Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Gilis E, Gaublomme D, Staal J, Venken K, Dhaenens M, Lambrecht S, Coudenys J, Decruy T, Schryvers N, Driege Y, Dumas E, Demeyer A, De Muynck A, van Hengel J, Van Hoorebeke L, Deforce D, Beyaert R, Elewaut D. MALT1-deletion in T-cells protects against the development of auto-immune arthritis, but causes spontaneous osteoporosis. Arthritis Rheumatol. 2019 Jul 01. PMID: 31259485.
      View in: PubMed
    2. Cambré I, Gaublomme D, Schryvers N, Lambrecht S, Lories R, Venken K, Elewaut D. Running promotes chronicity of arthritis by local modulation of complement activators and impairing T regulatory feedback loops. Ann Rheum Dis. 2019 Jun; 78(6):787-795. PMID: 30928902.
      View in: PubMed
    3. Venken K, Jacques P, Mortier C, Labadia ME, Decruy T, Coudenys J, Hoyt K, Wayne AL, Hughes R, Turner M, Van Gassen S, Martens L, Smith D, Harcken C, Wahle J, Wang CT, Verheugen E, Schryvers N, Varkas G, Cypers H, Wittoek R, Piette Y, Gyselbrecht L, Van Calenbergh S, Van den Bosch F, Saeys Y, Nabozny G, Elewaut D. ROR?t inhibition selectively targets IL-17 producing iNKT and ?d-T cells enriched in Spondyloarthritis patients. Nat Commun. 2019 01 02; 10(1):9. PMID: 30602780.
      View in: PubMed
    4. Janssens J, Bitra A, Wang J, Decruy T, Venken K, van der Eycken J, Elewaut D, Zajonc DM, van Calenbergh S. 4"-O-Alkylated a-Galactosylceramide Analogues as iNKT-Cell Antigens: Synthetic, Biological, and Structural Studies. ChemMedChem. 2019 Jan 08; 14(1):147-168. PMID: 30556652.
      View in: PubMed
    5. De Bruyne M, Bogaert DJ, Venken K, Van den Bossche L, Bonroy C, Roels L, Tavernier SJ, van de Vijver E, Driessen A, van Gijn M, Gámez-Diaz L, Elewaut D, Grimbacher B, Haerynck F, Moes N, Dullaers M. A novel LPS-responsive beige-like anchor protein (LRBA) mutation presents with normal cytotoxic T lymphocyte-associated protein 4 (CTLA-4) and overactive TH17 immunity. J Allergy Clin Immunol. 2018 Dec; 142(6):1968-1971. PMID: 30193839.
      View in: PubMed
    6. Venken K, Favreau M, Gaublomme D, Menu E, Vanderkerken K, Elewaut D. Checkpoint inhibition in the treatment of multiple myeloma: A way to boost innate-like T cell anti-tumor function? Mol Immunol. 2018 09; 101:521-526. PMID: 30153633.
      View in: PubMed
    7. Zhao M, Svensson MND, Venken K, Chawla A, Liang S, Engel I, Mydel P, Day J, Elewaut D, Bottini N, Kronenberg M. Altered thymic differentiation and modulation of arthritis by invariant NKT cells expressing mutant ZAP70. Nat Commun. 2018 07 06; 9(1):2627. PMID: 29980684.
      View in: PubMed
    8. Mortier C, Govindarajan S, Venken K, Elewaut D. It Takes "Guts" to Cause Joint Inflammation: Role of Innate-Like T Cells. Front Immunol. 2018; 9:1489. PMID: 30008717.
      View in: PubMed
    9. Gilis E, Mortier C, Venken K, Debusschere K, Vereecke L, Elewaut D. The Role of the Microbiome in Gut and Joint Inflammation in Psoriatic Arthritis and Spondyloarthritis. J Rheumatol Suppl. 2018 Jun; 94:36-39. PMID: 29858352.
      View in: PubMed
    10. Janssens J, Decruy T, Venken K, Seki T, Krols S, Van der Eycken J, Tsuji M, Elewaut D, Van Calenbergh S. Efficient Divergent Synthesis of New Immunostimulant 4?-Modified a-Galactosylceramide Analogues. ACS Med Chem Lett. 2017 Jun 08; 8(6):642-647. PMID: 28626526.
      View in: PubMed
    11. Favreau M, Venken K, Faict S, Maes K, De Veirman K, De Bruyne E, Leleu X, Boon L, Elewaut D, Vanderkerken K, Menu E. Both mucosal-associated invariant and natural killer T-cell deficiency in multiple myeloma can be countered by PD-1 inhibition. Haematologica. 2017 07; 102(7):e266-e270. PMID: 28385777.
      View in: PubMed
    12. Guillaume J, Seki T, Decruy T, Venken K, Elewaut D, Tsuji M, Van Calenbergh S. Synthesis of C6''-modified a-C-GalCer analogues as mouse and human iNKT cell agonists. Org Biomol Chem. 2017 Mar 08; 15(10):2217-2225. PMID: 28221388.
      View in: PubMed
    13. Palmer DJ, Grove NC, Ing J, Crane AM, Venken K, Davis BR, Ng P. Homology Requirements for Efficient, Footprintless Gene Editing at the CFTR Locus in Human iPSCs with Helper-dependent Adenoviral Vectors. Mol Ther Nucleic Acids. 2016 Oct 11; 5(10):e372. PMID: 27727248.
      View in: PubMed
    14. Favreau M, Vanderkerken K, Elewaut D, Venken K, Menu E. Does an NKT-cell-based immunotherapeutic approach have a future in multiple myeloma? Oncotarget. 2016 Apr 26; 7(17):23128-40. PMID: 26895468.
      View in: PubMed
    15. Venken K, Elewaut D. New immune cells in spondyloarthritis: Key players or innocent bystanders? Best Pract Res Clin Rheumatol. 2015 12; 29(6):706-14. PMID: 27107508.
      View in: PubMed
    16. Venken KJ, Sarrion-Perdigones A, Vandeventer PJ, Abel NS, Christiansen AE, Hoffman KL. Genome engineering: Drosophila melanogaster and beyond. Wiley Interdiscip Rev Dev Biol. 2016 Mar-Apr; 5(2):233-67. PMID: 26447401.
      View in: PubMed
    17. Nagarkar-Jaiswal S, Lee PT, Campbell ME, Chen K, Anguiano-Zarate S, Gutierrez MC, Busby T, Lin WW, He Y, Schulze KL, Booth BW, Evans-Holm M, Venken KJ, Levis RW, Spradling AC, Hoskins RA, Bellen HJ. A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila. Elife. 2015 Mar 31; 4. PMID: 25824290.
      View in: PubMed
    18. Gnerer JP, Venken KJ, Dierick HA. Gene-specific cell labeling using MiMIC transposons. Nucleic Acids Res. 2015 Apr 30; 43(8):e56. PMID: 25712101.
      View in: PubMed
    19. Shahab J, Baratta C, Scuric B, Godt D, Venken KJ, Ringuette MJ. Loss of SPARC dysregulates basal lamina assembly to disrupt larval fat body homeostasis in Drosophila melanogaster. Dev Dyn. 2015 Apr; 244(4):540-52. PMID: 25529377.
      View in: PubMed
    20. Haelterman NA, Jiang L, Li Y, Bayat V, Sandoval H, Ugur B, Tan KL, Zhang K, Bei D, Xiong B, Charng WL, Busby T, Jawaid A, David G, Jaiswal M, Venken KJ, Yamamoto S, Chen R, Bellen HJ. Large-scale identification of chemically induced mutations in Drosophila melanogaster. Genome Res. 2014 Oct; 24(10):1707-18. PMID: 25258387.
      View in: PubMed
    21. Venken KJ, Bellen HJ. Chemical mutagens, transposons, and transgenes to interrogate gene function in Drosophila melanogaster. Methods. 2014 Jun 15; 68(1):15-28. PMID: 24583113.
      View in: PubMed
    22. Cassidy JJ, Jha AR, Posadas DM, Giri R, Venken KJ, Ji J, Jiang H, Bellen HJ, White KP, Carthew RW. miR-9a minimizes the phenotypic impact of genomic diversity by buffering a transcription factor. Cell. 2013 Dec 19; 155(7):1556-67. PMID: 24360277.
      View in: PubMed
    23. Chen YC, Lin YQ, Banerjee S, Venken K, Li J, Ismat A, Chen K, Duraine L, Bellen HJ, Bhat MA. Drosophila neuroligin 2 is required presynaptically and postsynaptically for proper synaptic differentiation and synaptic transmission. J Neurosci. 2012 Nov 07; 32(45):16018-30. PMID: 23136438.
      View in: PubMed
    24. Szabad J, Bellen HJ, Venken KJ. An assay to detect in vivo Y chromosome loss in Drosophila wing disc cells. G3 (Bethesda). 2012 Sep; 2(9):1095-102. PMID: 22973547.
      View in: PubMed
    25. Alves-Silva J, Sánchez-Soriano N, Beaven R, Klein M, Parkin J, Millard TH, Bellen HJ, Venken KJ, Ballestrem C, Kammerer RA, Prokop A. Spectraplakins promote microtubule-mediated axonal growth by functioning as structural microtubule-associated proteins and EB1-dependent +TIPs (tip interacting proteins). J Neurosci. 2012 Jul 04; 32(27):9143-58. PMID: 22764224.
      View in: PubMed
    26. Geiser J, Venken KJ, De Lisle RC, Andrews GK. A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity. PLoS Genet. 2012; 8(6):e1002766. PMID: 22737083.
      View in: PubMed
    27. Venken KJ, Bellen HJ. Genome-wide manipulations of Drosophila melanogaster with transposons, Flp recombinase, and FC31 integrase. Methods Mol Biol. 2012; 859:203-28. PMID: 22367874.
      View in: PubMed
    28. Neumüller RA, Wirtz-Peitz F, Lee S, Kwon Y, Buckner M, Hoskins RA, Venken KJ, Bellen HJ, Mohr SE, Perrimon N. Stringent analysis of gene function and protein-protein interactions using fluorescently tagged genes. Genetics. 2012 Mar; 190(3):931-40. PMID: 22174071.
      View in: PubMed
    29. Venken KJ, Simpson JH, Bellen HJ. Genetic manipulation of genes and cells in the nervous system of the fruit fly. Neuron. 2011 Oct 20; 72(2):202-30. PMID: 22017985.
      View in: PubMed
    30. Venken KJ, Schulze KL, Haelterman NA, Pan H, He Y, Evans-Holm M, Carlson JW, Levis RW, Spradling AC, Hoskins RA, Bellen HJ. MiMIC: a highly versatile transposon insertion resource for engineering Drosophila melanogaster genes. Nat Methods. 2011 Sep; 8(9):737-43. PMID: 21985007.
      View in: PubMed
    31. Zheng L, Michelson Y, Freger V, Avraham Z, Venken KJ, Bellen HJ, Justice MJ, Wides R. Drosophila Ten-m and filamin affect motor neuron growth cone guidance. PLoS One. 2011; 6(8):e22956. PMID: 21857973.
      View in: PubMed
    32. Nègre N, Brown CD, Ma L, Bristow CA, Miller SW, Wagner U, Kheradpour P, Eaton ML, Loriaux P, Sealfon R, Li Z, Ishii H, Spokony RF, Chen J, Hwang L, Cheng C, Auburn RP, Davis MB, Domanus M, Shah PK, Morrison CA, Zieba J, Suchy S, Senderowicz L, Victorsen A, Bild NA, Grundstad AJ, Hanley D, MacAlpine DM, Mannervik M, Venken K, Bellen H, White R, Gerstein M, Russell S, Grossman RL, Ren B, Posakony JW, Kellis M, White KP. A cis-regulatory map of the Drosophila genome. Nature. 2011 Mar 24; 471(7339):527-31. PMID: 21430782.
      View in: PubMed
    33. Roy S, Ernst J, Kharchenko PV, Kheradpour P, Negre N, Eaton ML, Landolin JM, Bristow CA, Ma L, Lin MF, Washietl S, Arshinoff BI, Ay F, Meyer PE, Robine N, Washington NL, Di Stefano L, Berezikov E, Brown CD, Candeias R, Carlson JW, Carr A, Jungreis I, Marbach D, Sealfon R, Tolstorukov MY, Will S, Alekseyenko AA, Artieri C, Booth BW, Brooks AN, Dai Q, Davis CA, Duff MO, Feng X, Gorchakov AA, Gu T, Henikoff JG, Kapranov P, Li R, MacAlpine HK, Malone J, Minoda A, Nordman J, Okamura K, Perry M, Powell SK, Riddle NC, Sakai A, Samsonova A, Sandler JE, Schwartz YB, Sher N, Spokony R, Sturgill D, van Baren M, Wan KH, Yang L, Yu C, Feingold E, Good P, Guyer M, Lowdon R, Ahmad K, Andrews J, Berger B, Brenner SE, Brent MR, Cherbas L, Elgin SC, Gingeras TR, Grossman R, Hoskins RA, Kaufman TC, Kent W, Kuroda MI, Orr-Weaver T, Perrimon N, Pirrotta V, Posakony JW, Ren B, Russell S, Cherbas P, Graveley BR, Lewis S, Micklem G, Oliver B, Park PJ, Celniker SE, Henikoff S, Karpen GH, Lai EC, MacAlpine DM, Stein LD, White KP, Kellis M. Identification of functional elements and regulatory circuits by Drosophila modENCODE. Science. 2010 Dec 24; 330(6012):1787-97. PMID: 21177974.
      View in: PubMed
    34. Venken KJ, Popodi E, Holtzman SL, Schulze KL, Park S, Carlson JW, Hoskins RA, Bellen HJ, Kaufman TC. A molecularly defined duplication set for the X chromosome of Drosophila melanogaster. Genetics. 2010 Dec; 186(4):1111-25. PMID: 20876565.
      View in: PubMed
    35. Verstreken P, Ohyama T, Haueter C, Habets RL, Lin YQ, Swan LE, Ly CV, Venken KJ, De Camilli P, Bellen HJ. Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling. Neuron. 2009 Jul 30; 63(2):203-15. PMID: 19640479.
      View in: PubMed
    36. Venken KJ, Carlson JW, Schulze KL, Pan H, He Y, Spokony R, Wan KH, Koriabine M, de Jong PJ, White KP, Bellen HJ, Hoskins RA. Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster. Nat Methods. 2009 Jun; 6(6):431-4. PMID: 19465919.
      View in: PubMed
    37. Pepple KL, Atkins M, Venken K, Wellnitz K, Harding M, Frankfort B, Mardon G. Two-step selection of a single R8 photoreceptor: a bistable loop between senseless and rough locks in R8 fate. Development. 2008 Dec; 135(24):4071-9. PMID: 19004852.
      View in: PubMed
    38. Venken KJ, Kasprowicz J, Kuenen S, Yan J, Hassan BA, Verstreken P. Recombineering-mediated tagging of Drosophila genomic constructs for in vivo localization and acute protein inactivation. Nucleic Acids Res. 2008 Oct; 36(18):e114. PMID: 18676454.
      View in: PubMed
    39. Venken KJ, Bellen HJ. Transgenesis upgrades for Drosophila melanogaster. Development. 2007 Oct; 134(20):3571-84. PMID: 17905790.
      View in: PubMed
    40. Koh TW, Korolchuk VI, Wairkar YP, Jiao W, Evergren E, Pan H, Zhou Y, Venken KJ, Shupliakov O, Robinson IM, O'Kane CJ, Bellen HJ. Eps15 and Dap160 control synaptic vesicle membrane retrieval and synapse development. J Cell Biol. 2007 Jul 16; 178(2):309-22. PMID: 17620409.
      View in: PubMed
    41. Venken KJ, He Y, Hoskins RA, Bellen HJ. P[acman]: a BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster. Science. 2006 Dec 15; 314(5806):1747-51. PMID: 17138868.
      View in: PubMed
    42. Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY. Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15; 19(20):2412-7. PMID: 16230531.
      View in: PubMed
    43. Tsuda H, Jafar-Nejad H, Patel AJ, Sun Y, Chen HK, Rose MF, Venken KJ, Botas J, Orr HT, Bellen HJ, Zoghbi HY. The AXH domain of Ataxin-1 mediates neurodegeneration through its interaction with Gfi-1/Senseless proteins. Cell. 2005 Aug 26; 122(4):633-44. PMID: 16122429.
      View in: PubMed
    44. Verstreken P, Ly CV, Venken KJ, Koh TW, Zhou Y, Bellen HJ. Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions. Neuron. 2005 Aug 04; 47(3):365-78. PMID: 16055061.
      View in: PubMed
    45. Venken KJ, Bellen HJ. Emerging technologies for gene manipulation in Drosophila melanogaster. Nat Rev Genet. 2005 Mar; 6(3):167-78. PMID: 15738961.
      View in: PubMed
    46. Kazanjian A, Wallis D, Au N, Nigam R, Venken KJ, Cagle PT, Dickey BF, Bellen HJ, Gilks CB, Grimes HL. Growth factor independence-1 is expressed in primary human neuroendocrine lung carcinomas and mediates the differentiation of murine pulmonary neuroendocrine cells. Cancer Res. 2004 Oct 01; 64(19):6874-82. PMID: 15466176.
      View in: PubMed
    47. Watase K, Venken KJ, Sun Y, Orr HT, Zoghbi HY. Regional differences of somatic CAG repeat instability do not account for selective neuronal vulnerability in a knock-in mouse model of SCA1. Hum Mol Genet. 2003 Nov 01; 12(21):2789-95. PMID: 12952864.
      View in: PubMed
    48. Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ. The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development. 2003 Jan; 130(1):221-32. PMID: 12441305.
      View in: PubMed
    49. Venken K, Di Maria E, Bellone E, Balestra P, Cassandrini D, Mandich P, De Jonghe P, Timmerman V, Svaren J. Search for mutations in the EGR2 corepressor proteins, NAB1 and NAB2, in human peripheral neuropathies. Neurogenetics. 2002 Mar; 4(1):37-41. PMID: 12030330.
      View in: PubMed
    50. Irobi J, Nelis E, Meuleman J, Venken K, De Jonghe P, Van Broeckhoven C, Timmerman V. Exclusion of 5 functional candidate genes for distal hereditary motor neuropathy type II (distal HMN II) linked to 12q24.3. Ann Hum Genet. 2001 Nov; 65(Pt 6):517-29. PMID: 11851982.
      View in: PubMed
    51. Venken K, Meuleman J, Irobi J, Ceuterick C, Martini R, De Jonghe P, Timmerman V. Caspr1/Paranodin/Neurexin IV is most likely not a common disease-causing gene for inherited peripheral neuropathies. Neuroreport. 2001 Aug 08; 12(11):2609-14. PMID: 11496158.
      View in: PubMed
    VENKEN's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description