TitleDistinguished Service Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine

    Collapse Biography 
    Collapse awards and honors
    1996Marc Dresden Excellence in Graduate Education Award, Baylor College of Medicine
    2000Edwin B Astwood Lecture Award, Endocrine Society
    2002Barbara & Corbin J. Robertson, Jr. Presidential Award for Excellence in Education, Baylor College of Medicine
    2004Michael E. DeBakey Excellence in Research Award, Baylor College of Medicine
    2010Susan G. Komen for the Cure Brinker Basic Science Award, Komen Foundation
    2016AAAS Fellow, American Association for the Advancement of Science
    2017AACR Distinguished Lectureship in Breast Cancer Research, American Association of Cancer Research

    Collapse Research 
    Collapse research activities and funding
    R01CA195754     (PEROU, CHARLES M.)Aug 1, 2015 - Jul 31, 2019
    Mouse Models of Metastatic Triple-Negative Breast Cancer for Therapeutic Testing
    Role: Co-Principal Investigator

    R01CA148761     (PEROU, CHARLES M.)Mar 17, 2010 - Mar 31, 2026
    Therapeutic Targeting of Breast Cancer Tumor Initiating Cells
    Role: Co-Principal Investigator

    R21CA087383     (ROSEN, JEFFREY)Jul 14, 2000 - Jun 30, 2003
    Role: Principal Investigator

    U01CA084243     (ROSEN, JEFFREY)Sep 30, 1999 - Mar 31, 2010
    Mouse Models of Human Breast Cancer
    Role: Principal Investigator

    T32DK007696     (MOORE, DAVID D)Sep 5, 1993 - Aug 31, 2013
    Training Program in Molecular Endocrinology
    Role: Co-Principal Investigator

    R03TW000131     (ROSEN, JEFFREY)Dec 1, 1992 - Aug 31, 1997
    Role: Principal Investigator

    R13DK044290     (ROSEN, JEFFREY)Aug 4, 1991 - Jul 31, 1992
    Role: Principal Investigator

    R01CA016303     (ROSEN, JEFFREY MARK)Aug 1, 1978 - Feb 28, 2023
    Hormonal Regulation of Breast Cancer
    Role: Principal Investigator

    R37CA016303     (ROSEN, JEFFREY MARK)Aug 1, 1978 - Jul 31, 2012
    Hormonal Regulation of Breast Cancer
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Singh S, Lee N, Pedroza DA, Bado IL, Hamor C, Zhang L, Aguirre S, Hu J, Shen Y, Xu Y, Gao Y, Zhao N, Chen SH, Wan YW, Liu Z, Chang JT, Hollern D, Perou CM, Zhang XHF, Rosen JM. Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer. Cancer Res. 2022 06 15; 82(12):2281-2297. PMID: 35442423.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Janghorban M, Yang Y, Zhao N, Hamor C, Nguyen TM, Zhang XH, Rosen JM. Single-Cell Analysis Unveils the Role of the Tumor Immune Microenvironment and Notch Signaling in Dormant Minimal Residual Disease. Cancer Res. 2022 Mar 01; 82(5):885-899. PMID: 34965936.
      Citations: 2     Fields:    Translation:HumansCells
    3. Gao Y, Kabotyanski EB, Shepherd JH, Villegas E, Acosta D, Hamor C, Sun T, Montmeyor-Garcia C, He X, Dobrolecki LE, Westbrook TF, Lewis MT, Hilsenbeck SG, Zhang XH, Perou CM, Rosen JM. Tumor suppressor PLK2 may serve as a biomarker in triple-negative breast cancer for improved response to PLK1 therapeutics. Cancer Res Commun. 2021 Dec; 1(3):178-193. PMID: 35156101.
      Citations: 1     
    4. McGrail DJ, Pilié PG, Dai H, Lam TNA, Liang Y, Voorwerk L, Kok M, Zhang XH, Rosen JM, Heimberger AB, Peterson CB, Jonasch E, Lin SY. Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers. Sci Transl Med. 2021 Oct 27; 13(617):eabe6201. PMID: 34705519.
      Citations: 2     Fields:    Translation:Humans
    5. Zhao N, Rosen JM. Breast cancer heterogeneity through the lens of single-cell analysis and spatial pathologies. Semin Cancer Biol. 2022 07; 82:3-10. PMID: 34274486.
      Citations: 3     Fields:    Translation:Humans
    6. Zhao N, Powell RT, Yuan X, Bae G, Roarty KP, Stossi F, Strempfl M, Toneff MJ, Johnson HL, Mani SA, Jones P, Stephan CC, Rosen JM. Morphological screening of mesenchymal mammary tumor organoids to identify drugs that reverse epithelial-mesenchymal transition. Nat Commun. 2021 07 12; 12(1):4262. PMID: 34253738.
      Citations: 4     Fields:    Translation:Animals
    7. Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton KL, Tian L, den Hollander P, Isgandarova S, Haemmerle M, Mino B, Zhou T, Shin C, Martinez-Paniagua M, Sahin AA, Rodriguez-Canales J, Gelovani J, Chang JT, Acharya G, Sood AK, Wistuba II, Gibbons DL, Solis LM, Barton MC, Varadarajan N, Rosen JM, Zhang XH, Mani SA. CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021 07; 125(2):176-189. PMID: 33795809.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    8. Bowling EA, Wang JH, Gong F, Wu W, Neill NJ, Kim IS, Tyagi S, Orellana M, Kurley SJ, Dominguez-Vidaña R, Chung HC, Hsu TY, Dubrulle J, Saltzman AB, Li H, Meena JK, Canlas GM, Chamakuri S, Singh S, Simon LM, Olson CM, Dobrolecki LE, Lewis MT, Zhang B, Golding I, Rosen JM, Young DW, Malovannaya A, Stossi F, Miles G, Ellis MJ, Yu L, Buonamici S, Lin CY, Karlin KL, Zhang XH, Westbrook TF. Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer. Cell. 2021 01 21; 184(2):384-403.e21. PMID: 33450205.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    9. Singh S, Zhang XHF, Rosen JM. TIME Is a Great Healer-Targeting Myeloid Cells in the Tumor Immune Microenvironment to Improve Triple-Negative Breast Cancer Outcomes. Cells. 2020 12 23; 10(1). PMID: 33374595.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    10. Xu L, Liu X, Peng F, Zhang W, Zheng L, Ding Y, Gu T, Lv K, Wang J, Ortinau L, Hu T, Shi X, Shi G, Shang G, Sun S, Iwawaki T, Ji Y, Li W, Rosen JM, Zhang XH, Park D, Adoro S, Catic A, Tong W, Qi L, Nakada D, Chen X. Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions. Nat Cell Biol. 2020 10; 22(10):1162-1169. PMID: 32958856.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    11. Nguyen TM, Alchalabi S, Oluwatoyosi A, Ropri AS, Herschkowitz JI, Rosen JM. New twists on long noncoding RNAs: from mobile elements to motile cancer cells. RNA Biol. 2020 11; 17(11):1535-1549. PMID: 32522127.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    12. Lo HC, Xu Z, Kim IS, Pingel B, Aguirre S, Kodali S, Liu J, Zhang W, Muscarella AM, Hein SM, Krupnick AS, Neilson JR, Paust S, Rosen JM, Wang H, Zhang XH. Resistance to natural killer cell immunosurveillance confers a selective advantage to polyclonal metastasis. Nat Cancer. 2020 07; 1(7):709-722. PMID: 35122036.
      Citations: 10     Translation:AnimalsCells
    13. Lv X, Dobrolecki LE, Ding Y, Rosen JM, Lewis MT, Chen X. Orthotopic Transplantation of Breast Tumors as Preclinical Models for Breast Cancer. J Vis Exp. 2020 05 18; (159). PMID: 32478757.
      Citations: 1     Fields:    Translation:HumansAnimals
    14. Nguyen TM, Kabotyanski EB, Reineke LC, Shao J, Xiong F, Lee JH, Dubrulle J, Johnson H, Stossi F, Tsoi PS, Choi KJ, Ellis AG, Zhao N, Cao J, Adewunmi O, Ferreon JC, Ferreon ACM, Neilson JR, Mancini MA, Chen X, Kim J, Ma L, Li W, Rosen JM. The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis. Nucleic Acids Res. 2020 03 18; 48(5):2621-2642. PMID: 31863590.
      Citations: 25     Fields:    Translation:HumansCells
    15. Spike AJ, Rosen JM. C/EBPß Isoform Specific Gene Regulation: It's a Lot more Complicated than you Think! J Mammary Gland Biol Neoplasia. 2020 03; 25(1):1-12. PMID: 32078094.
      Citations: 1     Fields:    Translation:HumansAnimals
    16. Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng K, Niu Y, Goldstein A, Zhao N, Bado I, Lo HC, Toneff MJ, Nguyen T, Bu W, Jiang W, Arnold J, Gu F, He J, Jebakumar D, Walker K, Li Y, Mo Q, Westbrook TF, Zong C, Rao A, Sreekumar A, Rosen JM, Zhang XH. Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms. Nat Cell Biol. 2019 09; 21(9):1113-1126. PMID: 31451770.
      Citations: 88     Fields:    Translation:AnimalsCells
    17. Pfefferle AD, Darr DB, Calhoun BC, Mott KR, Rosen JM, Perou CM. The MMTV-Wnt1 murine model produces two phenotypically distinct subtypes of mammary tumors with unique therapeutic responses to an EGFR inhibitor. Dis Model Mech. 2019 07 05; 12(7). PMID: 31213486.
      Citations: 5     Fields:    Translation:AnimalsCells
    18. Soundararajan R, Fradette JJ, Konen JM, Moulder S, Zhang X, Gibbons DL, Varadarajan N, Wistuba II, Tripathy D, Bernatchez C, Byers LA, Chang JT, Contreras A, Lim B, Parra ER, Roarty EB, Wang J, Yang F, Barton M, Rosen JM, Mani SA. Targeting the Interplay between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy. Cancers (Basel). 2019 May 24; 11(5). PMID: 31137625.
      Citations: 42     
    19. Gao Y, Bado I, Wang H, Zhang W, Rosen JM, Zhang XH. Metastasis Organotropism: Redefining the Congenial Soil. Dev Cell. 2019 05 06; 49(3):375-391. PMID: 31063756.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    20. Vijay GV, Zhao N, Den Hollander P, Toneff MJ, Joseph R, Pietila M, Taube JH, Sarkar TR, Ramirez-Pena E, Werden SJ, Shariati M, Gao R, Sobieski M, Stephan CC, Sphyris N, Miura N, Davies P, Chang JT, Soundararajan R, Rosen JM, Mani SA. GSK3ß regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer. Breast Cancer Res. 2019 03 07; 21(1):37. PMID: 30845991.
      Citations: 34     Fields:    Translation:HumansCells
    21. Lu Y, Cao J, Napoli M, Xia Z, Zhao N, Creighton CJ, Li W, Chen X, Flores ER, McManus MT, Rosen JM. miR-205 Regulates Basal Cell Identity and Stem Cell Regenerative Potential During Mammary Reconstitution. Stem Cells. 2018 12; 36(12):1875-1889. PMID: 30267595.
      Citations: 7     Fields:    Translation:Animals
    22. Janghorban M, Xin L, Rosen JM, Zhang XH. Notch Signaling as a Regulator of the Tumor Immune Response: To Target or Not To Target? Front Immunol. 2018; 9:1649. PMID: 30061899.
      Citations: 40     Fields:    
    23. Nguyen TM, Kabotyanski EB, Dou Y, Reineke LC, Zhang P, Zhang XH, Malovannaya A, Jung SY, Mo Q, Roarty KP, Chen Y, Zhang B, Neilson JR, Lloyd RE, Perou CM, Ellis MJ, Rosen JM. FGFR1-Activated Translation of WNT Pathway Components with Structured 5' UTRs Is Vulnerable to Inhibition of EIF4A-Dependent Translation Initiation. Cancer Res. 2018 08 01; 78(15):4229-4240. PMID: 29844125.
      Citations: 9     Fields:    Translation:AnimalsCells
    24. Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson JB, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X. Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. J Clin Invest. 2018 04 02; 128(4):1283-1299. PMID: 29480818.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    25. Zhang P, He D, Xu Y, Hou J, Pan BF, Wang Y, Liu T, Davis CM, Ehli EA, Tan L, Zhou F, Hu J, Yu Y, Chen X, Nguyen TM, Rosen JM, Hawke DH, Ji Z, Chen Y. Genome-wide identification and differential analysis of translational initiation. Nat Commun. 2017 11 23; 8(1):1749. PMID: 29170441.
      Citations: 36     Fields:    Translation:HumansCells
    26. Sreekumar A, Toneff MJ, Toh E, Roarty K, Creighton CJ, Belka GK, Lee DK, Xu J, Chodosh LA, Richards JS, Rosen JM. WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis. Dev Cell. 2017 11 20; 43(4):436-448.e6. PMID: 29103953.
      Citations: 17     Fields:    Translation:AnimalsCells
    27. Roarty K, Pfefferle AD, Creighton CJ, Perou CM, Rosen JM. Ror2-mediated alternative Wnt signaling regulates cell fate and adhesion during mammary tumor progression. Oncogene. 2017 10 26; 36(43):5958-5968. PMID: 28650466.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    28. Zhang M, Lee AV, Rosen JM. The Cellular Origin and Evolution of Breast Cancer. Cold Spring Harb Perspect Med. 2017 Mar 01; 7(3). PMID: 28062556.
      Citations: 36     Fields:    Translation:HumansCells
    29. Welte T, Zhang XH, Rosen JM. Repurposing Antiestrogens for Tumor Immunotherapy. Cancer Discov. 2017 01; 7(1):17-19. PMID: 28062672.
      Citations: 6     Fields:    Translation:HumansCells
    30. Su X, Napoli M, Abbas HA, Venkatanarayan A, Bui NHB, Coarfa C, Gi YJ, Kittrell F, Gunaratne PH, Medina D, Rosen JM, Behbod F, Flores ER. TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway. Oncogene. 2017 04 27; 36(17):2377-2393. PMID: 27869165.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    31. Welte T, Rosen JM, Zhang XH. Fatal attraction: TICs and MDSCs. Cell Cycle. 2016 10; 15(19):2545-2546. PMID: 27574951.
      Citations: 1     Fields:    Translation:Cells
    32. Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, Mo Q, Edwards DP, Huang S, Xin L, Xu J, Li Y, Lewis MT, Wang T, Westbrook TF, Rosen JM, Zhang XH. Erratum: Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 2016 06 28; 18(7):822. PMID: 27350446.
      Citations: 1     Fields:    
    33. Welte T, Kim IS, Tian L, Gao X, Wang H, Li J, Holdman XB, Herschkowitz JI, Pond A, Xie G, Kurley S, Nguyen T, Liao L, Dobrolecki LE, Pang L, Mo Q, Edwards DP, Huang S, Xin L, Xu J, Li Y, Lewis MT, Wang T, Westbrook TF, Rosen JM, Zhang XH. Oncogenic mTOR signalling recruits myeloid-derived suppressor cells to promote tumour initiation. Nat Cell Biol. 2016 06; 18(6):632-44. PMID: 27183469.
      Citations: 98     Fields:    Translation:HumansAnimalsCells
    34. Pfefferle AD, Agrawal YN, Koboldt DC, Kanchi KL, Herschkowitz JI, Mardis ER, Rosen JM, Perou CM. Genomic profiling of murine mammary tumors identifies potential personalized drug targets for p53-deficient mammary cancers. Dis Model Mech. 2016 07 01; 9(7):749-57. PMID: 27149990.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    35. Paine I, Chauviere A, Landua J, Sreekumar A, Cristini V, Rosen J, Lewis MT. A Geometrically-Constrained Mathematical Model of Mammary Gland Ductal Elongation Reveals Novel Cellular Dynamics within the Terminal End Bud. PLoS Comput Biol. 2016 Apr; 12(4):e1004839. PMID: 27115287.
      Citations: 23     Fields:    Translation:Animals
    36. Zhang M, Rosen JM. Developmental Insights into Breast Cancer Intratumoral Heterogeneity. Trends Cancer. 2015 Dec 01; 1(4):242-251. PMID: 26753176.
      Citations: 11     Fields:    
    37. Holdman XB, Welte T, Rajapakshe K, Pond A, Coarfa C, Mo Q, Huang S, Hilsenbeck SG, Edwards DP, Zhang X, Rosen JM. Upregulation of EGFR signaling is correlated with tumor stroma remodeling and tumor recurrence in FGFR1-driven breast cancer. Breast Cancer Res. 2015 Nov 18; 17:141. PMID: 26581390.
      Citations: 35     Fields:    Translation:AnimalsCells
    38. Shore AN, Chang CH, Kwon OJ, Weston MC, Zhang M, Xin L, Rosen JM. PTEN is required to maintain luminal epithelial homeostasis and integrity in the adult mammary gland. Dev Biol. 2016 Jan 01; 409(1):202-217. PMID: 26526198.
      Citations: 8     Fields:    Translation:AnimalsCells
    39. Chang CH, Zhang M, Rajapakshe K, Coarfa C, Edwards D, Huang S, Rosen JM. Mammary Stem Cells and Tumor-Initiating Cells Are More Resistant to Apoptosis and Exhibit Increased DNA Repair Activity in Response to DNA Damage. Stem Cell Reports. 2015 Sep 08; 5(3):378-91. PMID: 26300228.
      Citations: 40     Fields:    Translation:AnimalsCells
    40. Sreekumar A, Roarty K, Rosen JM. The mammary stem cell hierarchy: a looking glass into heterogeneous breast cancer landscapes. Endocr Relat Cancer. 2015 Dec; 22(6):T161-76. PMID: 26206777.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    41. Silva GO, He X, Parker JS, Gatza ML, Carey LA, Hou JP, Moulder SL, Marcom PK, Ma J, Rosen JM, Perou CM. Cross-species DNA copy number analyses identifies multiple 1q21-q23 subtype-specific driver genes for breast cancer. Breast Cancer Res Treat. 2015 Jul; 152(2):347-56. PMID: 26109346.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    42. Knezevic J, Pfefferle AD, Petrovic I, Greene SB, Perou CM, Rosen JM. Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential. Oncogene. 2015 Dec 03; 34(49):5997-6006. PMID: 25746005.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    43. Zhang M, Tsimelzon A, Chang CH, Fan C, Wolff A, Perou CM, Hilsenbeck SG, Rosen JM. Intratumoral heterogeneity in a Trp53-null mouse model of human breast cancer. Cancer Discov. 2015 May; 5(5):520-33. PMID: 25735774.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    44. Roarty K, Shore AN, Creighton CJ, Rosen JM. Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium. J Cell Biol. 2015 Feb 02; 208(3):351-66. PMID: 25624393.
      Citations: 23     Fields:    Translation:AnimalsCells
    45. Wang H, Yu C, Gao X, Welte T, Muscarella AM, Tian L, Zhao H, Zhao Z, Du S, Tao J, Lee B, Westbrook TF, Wong ST, Jin X, Rosen JM, Osborne CK, Zhang XH. The osteogenic niche promotes early-stage bone colonization of disseminated breast cancer cells. Cancer Cell. 2015 Feb 09; 27(2):193-210. PMID: 25600338.
      Citations: 170     Fields:    Translation:HumansCells
    46. Karlin KL, Mondal G, Hartman JK, Tyagi S, Kurley SJ, Bland CS, Hsu TY, Renwick A, Fang JE, Migliaccio I, Callaway C, Nair A, Dominguez-Vidana R, Nguyen DX, Osborne CK, Schiff R, Yu-Lee LY, Jung SY, Edwards DP, Hilsenbeck SG, Rosen JM, Zhang XH, Shaw CA, Couch FJ, Westbrook TF. The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor. Cell Rep. 2014 Nov 20; 9(4):1318-32. PMID: 25453754.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    47. Wei W, Tweardy DJ, Tweardy DJ, Zhang M, Zhang X, Landua J, Petrovic I, Bu W, Roarty K, Hilsenbeck SG, Rosen JM, Lewis MT. STAT3 signaling is activated preferentially in tumor-initiating cells in claudin-low models of human breast cancer. Stem Cells. 2014 Oct; 32(10):2571-82. PMID: 24891218.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    48. Vadakkan TJ, Landua JD, Bu W, Wei W, Li F, Wong ST, Dickinson ME, Rosen JM, Lewis MT, Zhang M. Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer. Stem Cells Transl Med. 2014 Jul; 3(7):857-66. PMID: 24797826.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    49. Shore AN, Rosen JM. Regulation of mammary epithelial cell homeostasis by lncRNAs. Int J Biochem Cell Biol. 2014 Sep; 54:318-30. PMID: 24680897.
      Citations: 14     Fields:    Translation:HumansCells
    50. Villegas E, Kabotyanski EB, Shore AN, Creighton CJ, Westbrook TF, Rosen JM. Plk2 regulates mitotic spindle orientation and mammary gland development. Development. 2014 Apr; 141(7):1562-71. PMID: 24598160.
      Citations: 15     Fields:    Translation:AnimalsCells
    51. Rosen JM, Roarty K. Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity? Breast Cancer Res. 2014 Jan 29; 16(1):202. PMID: 24476463.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    52. Roarty K, Rosen JM. Pygopus 2: tilting the Wnt-Notch balance in mammary epithelial lineage determination. Breast Cancer Res. 2013 Dec 23; 15(6):322. PMID: 24365076.
      Citations:    Fields:    Translation:AnimalsCells
    53. Pfefferle AD, Herschkowitz JI, Usary J, Harrell JC, Spike BT, Adams JR, Torres-Arzayus MI, Brown M, Egan SE, Wahl GM, Rosen JM, Perou CM. Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biol. 2013 Nov 12; 14(11):R125. PMID: 24220145.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    54. Zhu Y, Li F, Vadakkan TJ, Zhang M, Landua J, Wei W, Ma J, Dickinson ME, Rosen JM, Lewis MT, Zhan M, Wong ST. Three-dimensional vasculature reconstruction of tumour microenvironment via local clustering and classification. Interface Focus. 2013 Aug 06; 3(4):20130015. PMID: 24511379.
      Citations: 4     
    55. Usary J, Zhao W, Darr D, Roberts PJ, Liu M, Balletta L, Karginova O, Jordan J, Combest A, Bridges A, Prat A, Cheang MC, Herschkowitz JI, Rosen JM, Zamboni W, Sharpless NE, Perou CM. Predicting drug responsiveness in human cancers using genetically engineered mice. Clin Cancer Res. 2013 Sep 01; 19(17):4889-99. PMID: 23780888.
      Citations: 36     Fields:    Translation:HumansAnimals
    56. Machado HL, Kittrell FS, Edwards D, White AN, Atkinson RL, Rosen JM, Medina D, Lewis MT. Separation by cell size enriches for mammary stem cell repopulation activity. Stem Cells Transl Med. 2013 Mar; 2(3):199-203. PMID: 23408103.
      Citations: 10     Fields:    Translation:AnimalsCells
    57. Hollier BG, Tinnirello AA, Werden SJ, Evans KW, Taube JH, Sarkar TR, Sphyris N, Shariati M, Kumar SV, Battula VL, Herschkowitz JI, Guerra R, Chang JT, Miura N, Rosen JM, Mani SA. FOXC2 expression links epithelial-mesenchymal transition and stem cell properties in breast cancer. Cancer Res. 2013 Mar 15; 73(6):1981-92. PMID: 23378344.
      Citations: 132     Fields:    Translation:HumansAnimalsCells
    58. Taube JH, Malouf GG, Lu E, Sphyris N, Vijay V, Ramachandran PP, Ueno KR, Gaur S, Nicoloso MS, Rossi S, Herschkowitz JI, Rosen JM, Issa JP, Calin GA, Chang JT, Mani SA. Epigenetic silencing of microRNA-203 is required for EMT and cancer stem cell properties. Sci Rep. 2013; 3:2687. PMID: 24045437.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    59. Pond AC, Bin X, Batts T, Roarty K, Hilsenbeck S, Rosen JM. Fibroblast growth factor receptor signaling is essential for normal mammary gland development and stem cell function. Stem Cells. 2013 Jan; 31(1):178-89. PMID: 23097355.
      Citations: 49     Fields:    Translation:AnimalsCells
    60. Shore AN, Kabotyanski EB, Roarty K, Smith MA, Zhang Y, Creighton CJ, Dinger ME, Rosen JM. Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation. PLoS Genet. 2012; 8(7):e1002840. PMID: 22911650.
      Citations: 28     Fields:    Translation:Animals
    61. Rosen JM. On murine mammary epithelial stem cells: discovery, function, and current status. Cold Spring Harb Perspect Biol. 2012 Apr 01; 4(4):a013268. PMID: 22474010.
      Citations: 2     Fields:    Translation:AnimalsCells
    62. Shore AN, Herschkowitz JI, Rosen JM. Noncoding RNAs involved in mammary gland development and tumorigenesis: there's a long way to go. J Mammary Gland Biol Neoplasia. 2012 Mar; 17(1):43-58. PMID: 22402938.
      Citations: 27     Fields:    Translation:HumansAnimals
    63. Behbod F, Rosen JM. Mammary gland development & breast cancer; connecting the dots by non-coding RNAs. J Mammary Gland Biol Neoplasia. 2012 Mar; 17(1):1-2. PMID: 22402939.
      Citations:    Fields:    Translation:Humans
    64. Rijnkels M, Kabotyanski E, Shore A, Rosen JM. The chromatin landscape of the casein gene locus. Horm Mol Biol Clin Investig. 2012 Mar 01; 10(1):201-205. PMID: 23914258.
      Citations: 3     Fields:    
    65. Zhang L, Zhang B, Han SJ, Shore AN, Rosen JM, Demayo FJ, Xin L. Targeting CreER(T2) expression to keratin 8-expressing murine simple epithelia using bacterial artificial chromosome transgenesis. Transgenic Res. 2012 Oct; 21(5):1117-23. PMID: 22350718.
      Citations: 13     Fields:    Translation:AnimalsCells
    66. Rosen JM. On hormone action in the mammary gland. Cold Spring Harb Perspect Biol. 2012 Feb 01; 4(2). PMID: 22300979.
      Citations: 4     Fields:    Translation:HumansAnimals
    67. Shahi P, Park D, Pond AC, Seethammagari M, Chiou SH, Cho K, Carstens JL, Decker WK, McCrea PD, Ittmann MM, Rosen JM, Spencer DM. Activation of Wnt signaling by chemically induced dimerization of LRP5 disrupts cellular homeostasis. PLoS One. 2012; 7(1):e30814. PMID: 22303459.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    68. Batts TD, Machado HL, Zhang Y, Creighton CJ, Li Y, Rosen JM. Stem cell antigen-1 (sca-1) regulates mammary tumor development and cell migration. PLoS One. 2011; 6(11):e27841. PMID: 22140470.
      Citations: 12     Fields:    Translation:AnimalsCells
    69. Heckman-Stoddard BM, Vargo-Gogola T, Herrick MP, Visbal AP, Lewis MT, Settleman J, Rosen JM. P190A RhoGAP is required for mammary gland development. Dev Biol. 2011 Dec 01; 360(1):1-10. PMID: 21945077.
      Citations: 9     Fields:    Translation:AnimalsCells
    70. Rainusso N, Man TK, Lau CC, Hicks J, Shen JJ, Yu A, Wang LL, Rosen JM. Identification and gene expression profiling of tumor-initiating cells isolated from human osteosarcoma cell lines in an orthotopic mouse model. Cancer Biol Ther. 2011 Aug 15; 12(4):278-87. PMID: 21617384.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    71. Herschkowitz JI, Zhao W, Zhang M, Usary J, Murrow G, Edwards D, Knezevic J, Greene SB, Darr D, Troester MA, Hilsenbeck SG, Medina D, Perou CM, Rosen JM. Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):2778-83. PMID: 21633010.
      Citations: 123     Fields:    Translation:HumansAnimalsCells
    72. Buser AC, Obr AE, Kabotyanski EB, Grimm SL, Rosen JM, Edwards DP. Progesterone receptor directly inhibits ß-casein gene transcription in mammary epithelial cells through promoting promoter and enhancer repressive chromatin modifications. Mol Endocrinol. 2011 Jun; 25(6):955-68. PMID: 21527503.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    73. Kittrell FS, Carletti MZ, Kerbawy S, Heestand J, Xian W, Zhang M, Lamarca HL, Sonnenberg A, Rosen JM, Medina D, Behbod F. Prospective isolation and characterization of committed and multipotent progenitors from immortalized mouse mammary epithelial cells with morphogenic potential. Breast Cancer Res. 2011 Apr 05; 13(2):R41. PMID: 21466693.
      Citations: 7     Fields:    Translation:AnimalsCells
    74. Peddibhotla S, Wei Z, Papineni R, Lam MH, Rosen JM, Zhang P. The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression. Cell Cycle. 2011 Feb 15; 10(4):671-9. PMID: 21301228.
      Citations: 9     Fields:    Translation:HumansCells
    75. Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, Schiff R, Rosen JM, Westbrook TF, Elledge SJ. The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo. Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3665-70. PMID: 21307310.
      Citations: 356     Fields:    Translation:HumansAnimalsCells
    76. Visbal AP, LaMarca HL, Villanueva H, Toneff MJ, Li Y, Rosen JM, Lewis MT. Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened. Dev Biol. 2011 Apr 01; 352(1):116-27. PMID: 21276786.
      Citations: 26     Fields:    Translation:AnimalsCells
    77. Wei Z, Peddibhotla S, Lin H, Fang X, Li M, Rosen JM, Zhang P. Early-onset aging and defective DNA damage response in Cdc14b-deficient mice. Mol Cell Biol. 2011 Apr; 31(7):1470-7. PMID: 21262768.
      Citations: 22     Fields:    Translation:AnimalsCells
    78. Roarty K, Rosen JM. Wnt and mammary stem cells: hormones cannot fly wingless. Curr Opin Pharmacol. 2010 Dec; 10(6):643-9. PMID: 20810315.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    79. Atkinson RL, Zhang M, Diagaradjane P, Peddibhotla S, Contreras A, Hilsenbeck SG, Woodward WA, Krishnan S, Chang JC, Rosen JM. Thermal enhancement with optically activated gold nanoshells sensitizes breast cancer stem cells to radiation therapy. Sci Transl Med. 2010 Oct 27; 2(55):55ra79. PMID: 20980696.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    80. McHenry PR, Sears JC, Herrick MP, Chang P, Heckman-Stoddard BM, Rybarczyk M, Chodosh LA, Gunther EJ, Hilsenbeck SG, Rosen JM, Vargo-Gogola T. P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis. Breast Cancer Res. 2010; 12(5):R73. PMID: 20860838.
      Citations: 21     Fields:    Translation:AnimalsCells
    81. Greene SB, Herschkowitz JI, Rosen JM. Small players with big roles: microRNAs as targets to inhibit breast cancer progression. Curr Drug Targets. 2010 Sep; 11(9):1059-73. PMID: 20545613.
      Citations: 20     Fields:    Translation:HumansCells
    82. Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander ES, Rosen JM, Weinberg RA, Mani SA. Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proc Natl Acad Sci U S A. 2010 Aug 31; 107(35):15449-54. PMID: 20713713.
      Citations: 535     Fields:    Translation:HumansCells
    83. Dong J, Tong T, Reynado AM, Rosen JM, Huang S, Li Y. Genetic manipulation of individual somatic mammary cells in vivo reveals a master role of STAT5a in inducing alveolar fate commitment and lactogenesis even in the absence of ovarian hormones. Dev Biol. 2010 Oct 15; 346(2):196-203. PMID: 20691178.
      Citations: 13     Fields:    Translation:AnimalsCells
    84. Pond AC, Herschkowitz JI, Schwertfeger KL, Welm B, Zhang Y, York B, Cardiff RD, Hilsenbeck S, Perou CM, Creighton CJ, Lloyd RE, Rosen JM. Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer. Cancer Res. 2010 Jun 15; 70(12):4868-79. PMID: 20501844.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    85. Greene SB, Herschkowitz JI, Rosen JM. The ups and downs of miR-205: identifying the roles of miR-205 in mammary gland development and breast cancer. RNA Biol. 2010 May-Jun; 7(3):300-4. PMID: 20436283.
      Citations: 38     Fields:    Translation:HumansAnimals
    86. Creighton CJ, Chang JC, Rosen JM. Epithelial-mesenchymal transition (EMT) in tumor-initiating cells and its clinical implications in breast cancer. J Mammary Gland Biol Neoplasia. 2010 Jun; 15(2):253-60. PMID: 20354771.
      Citations: 126     Fields:    Translation:HumansAnimalsCells
    87. LaMarca HL, Visbal AP, Creighton CJ, Liu H, Zhang Y, Behbod F, Rosen JM. CCAAT/enhancer binding protein beta regulates stem cell activity and specifies luminal cell fate in the mammary gland. Stem Cells. 2010 Mar 31; 28(3):535-44. PMID: 20054865.
      Citations: 34     Fields:    Translation:AnimalsCells
    88. Rijnkels M, Kabotyanski E, Montazer-Torbati MB, Hue Beauvais C, Vassetzky Y, Rosen JM, Devinoy E. The epigenetic landscape of mammary gland development and functional differentiation. J Mammary Gland Biol Neoplasia. 2010 Mar; 15(1):85-100. PMID: 20157770.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    89. Reddy JP, Peddibhotla S, Bu W, Zhao J, Haricharan S, Du YC, Podsypanina K, Rosen JM, Donehower LA, Li Y. Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3728-33. PMID: 20133707.
      Citations: 33     Fields:    Translation:Animals
    90. Zhang M, Atkinson RL, Rosen JM. Selective targeting of radiation-resistant tumor-initiating cells. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3522-7. PMID: 20133717.
      Citations: 99     Fields:    Translation:AnimalsCells
    91. Greene SB, Gunaratne PH, Hammond SM, Rosen JM. A putative role for microRNA-205 in mammary epithelial cell progenitors. J Cell Sci. 2010 Feb 15; 123(Pt 4):606-18. PMID: 20103531.
      Citations: 75     Fields:    Translation:AnimalsCells
    92. Boles NC, Peddibhotla S, Chen AJ, Goodell MA, Rosen JM. Chk1 haploinsufficiency results in anemia and defective erythropoiesis. PLoS One. 2010 Jan 05; 5(1):e8581. PMID: 20052416.
      Citations: 17     Fields:    Translation:HumansAnimals
    93. Heckman-Stoddard BM, Vargo-Gogola T, McHenry PR, Jiang V, Herrick MP, Hilsenbeck SG, Settleman J, Rosen JM. Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression. Breast Cancer Res. 2009; 11(4):R61. PMID: 19703301.
      Citations: 20     Fields:    Translation:AnimalsCells
    94. Rosen JM, Woo SL, Comstock JP. Regulation of casein messenger RNA during the development of the rat mammary gland. 1975. J Mammary Gland Biol Neoplasia. 2009 Sep; 14(3):343-51. PMID: 19653075.
      Citations: 1     Fields:    Translation:Animals
    95. Creighton CJ, Li X, Landis M, Dixon JM, Neumeister VM, Sjolund A, Rimm DL, Wong H, Rodriguez A, Herschkowitz JI, Fan C, Zhang X, He X, Pavlick A, Gutierrez MC, Renshaw L, Larionov AA, Faratian D, Hilsenbeck SG, Perou CM, Lewis MT, Rosen JM, Chang JC. Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features. Proc Natl Acad Sci U S A. 2009 Aug 18; 106(33):13820-5. PMID: 19666588.
      Citations: 707     Fields:    Translation:HumansCells
    96. Peddibhotla S, Rosen JM. Chking and executing cell division to prevent genomic instability. Cell Cycle. 2009 Aug; 8(15):2339-42. PMID: 19571679.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    97. Rosen JM, Jordan CT. The increasing complexity of the cancer stem cell paradigm. Science. 2009 Jun 26; 324(5935):1670-3. PMID: 19556499.
      Citations: 325     Fields:    Translation:HumansAnimalsCells
    98. Kabotyanski EB, Rijnkels M, Freeman-Zadrowski C, Buser AC, Edwards DP, Rosen JM. Lactogenic hormonal induction of long distance interactions between beta-casein gene regulatory elements. J Biol Chem. 2009 Aug 21; 284(34):22815-24. PMID: 19542223.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    99. Peddibhotla S, Lam MH, Gonzalez-Rimbau M, Rosen JM. The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis. Proc Natl Acad Sci U S A. 2009 Mar 31; 106(13):5159-64. PMID: 19289837.
      Citations: 44     Fields:    Translation:AnimalsCells
    100. Xian W, Pappas L, Pandya D, Selfors LM, Derksen PW, de Bruin M, Gray NS, Jonkers J, Rosen JM, Brugge JS. Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival. Cancer Res. 2009 Mar 15; 69(6):2244-51. PMID: 19258500.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    101. Behbod F, Kittrell FS, LaMarca H, Edwards D, Kerbawy S, Heestand JC, Young E, Mukhopadhyay P, Yeh HW, Allred DC, Hu M, Polyak K, Rosen JM, Medina D. An intraductal human-in-mouse transplantation model mimics the subtypes of ductal carcinoma in situ. Breast Cancer Res. 2009; 11(5):R66. PMID: 19735549.
      Citations: 123     Fields:    Translation:HumansAnimalsCells
    102. Zhang M, Behbod F, Atkinson RL, Landis MD, Kittrell F, Edwards D, Medina D, Tsimelzon A, Hilsenbeck S, Green JE, Michalowska AM, Rosen JM. Identification of tumor-initiating cells in a p53-null mouse model of breast cancer. Cancer Res. 2008 Jun 15; 68(12):4674-82. PMID: 18559513.
      Citations: 158     Fields:    Translation:AnimalsCells
    103. LaMarca HL, Rosen JM. Minireview: hormones and mammary cell fate--what will I become when I grow up? Endocrinology. 2008 Sep; 149(9):4317-21. PMID: 18556345.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    104. Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC, Wong H, Rosen J, Chang JC. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst. 2008 May 07; 100(9):672-9. PMID: 18445819.
      Citations: 817     Fields:    Translation:Humans
    105. Vargo-Gogola T, Rosen JM. Modelling breast cancer: one size does not fit all. Nat Rev Cancer. 2007 Sep; 7(9):659-72. PMID: 17721431.
      Citations: 267     Fields:    Translation:AnimalsCells
    106. Heckman BM, Chakravarty G, Vargo-Gogola T, Gonzales-Rimbau M, Hadsell DL, Lee AV, Settleman J, Rosen JM. Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development. Dev Biol. 2007 Sep 01; 309(1):137-49. PMID: 17662267.
      Citations: 24     Fields:    Translation:AnimalsCells
    107. Mukhopadhyay SS, Rosen JM. The C-terminal domain of the nuclear factor I-B2 isoform is glycosylated and transactivates the WAP gene in the JEG-3 cells. Biochem Biophys Res Commun. 2007 Jul 06; 358(3):770-6. PMID: 17511965.
      Citations: 6     Fields:    Translation:HumansCells
    108. Xian W, Schwertfeger KL, Rosen JM. Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition. Mol Endocrinol. 2007 Apr; 21(4):987-1000. PMID: 17284663.
      Citations: 35     Fields:    Translation:AnimalsCells
    109. Chen MS, Woodward WA, Behbod F, Peddibhotla S, Alfaro MP, Buchholz TA, Rosen JM. Wnt/beta-catenin mediates radiation resistance of Sca1+ progenitors in an immortalized mammary gland cell line. J Cell Sci. 2007 Feb 01; 120(Pt 3):468-77. PMID: 17227796.
      Citations: 87     Fields:    Translation:AnimalsCells
    110. Woodward WA, Chen MS, Behbod F, Alfaro MP, Buchholz TA, Rosen JM. WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells. Proc Natl Acad Sci U S A. 2007 Jan 09; 104(2):618-23. PMID: 17202265.
      Citations: 294     Fields:    Translation:HumansAnimalsCells
    111. LaMarca HL, Rosen JM. Estrogen regulation of mammary gland development and breast cancer: amphiregulin takes center stage. Breast Cancer Res. 2007; 9(4):304. PMID: 17659070.
      Citations: 30     Fields:    Translation:Humans
    112. Schwertfeger KL, Rosen JM, Cohen DA. Mammary gland macrophages: pleiotropic functions in mammary development. J Mammary Gland Biol Neoplasia. 2006 Oct; 11(3-4):229-38. PMID: 17115264.
      Citations: 35     Fields:    Translation:AnimalsCells
    113. Buser AC, Gass-Handel EK, Wyszomierski SL, Doppler W, Leonhardt SA, Schaack J, Rosen JM, Watkin H, Anderson SM, Edwards DP. Progesterone receptor repression of prolactin/signal transducer and activator of transcription 5-mediated transcription of the beta-casein gene in mammary epithelial cells. Mol Endocrinol. 2007 Jan; 21(1):106-25. PMID: 16973758.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    114. Grimm SL, Bu W, Longley MA, Roop DR, Li Y, Rosen JM. Keratin 6 is not essential for mammary gland development. Breast Cancer Res. 2006; 8(3):R29. PMID: 16790075.
      Citations: 21     Fields:    Translation:AnimalsCells
    115. Kabotyanski EB, Huetter M, Xian W, Rijnkels M, Rosen JM. Integration of prolactin and glucocorticoid signaling at the beta-casein promoter and enhancer by ordered recruitment of specific transcription factors and chromatin modifiers. Mol Endocrinol. 2006 Oct; 20(10):2355-68. PMID: 16772529.
      Citations: 34     Fields:    Translation:AnimalsCells
    116. Schwertfeger KL, Xian W, Kaplan AM, Burnett SH, Cohen DA, Rosen JM. A critical role for the inflammatory response in a mouse model of preneoplastic progression. Cancer Res. 2006 Jun 01; 66(11):5676-85. PMID: 16740705.
      Citations: 34     Fields:    Translation:AnimalsCells
    117. Cella N, Contreras A, Latha K, Rosen JM, Zhang M. Maspin is physically associated with [beta]1 integrin regulating cell adhesion in mammary epithelial cells. FASEB J. 2006 Jul; 20(9):1510-2. PMID: 16720730.
      Citations: 31     Fields:    Translation:HumansCells
    118. Ginger MR, Shore AN, Contreras A, Rijnkels M, Miller J, Gonzalez-Rimbau MF, Rosen JM. A noncoding RNA is a potential marker of cell fate during mammary gland development. Proc Natl Acad Sci U S A. 2006 Apr 11; 103(15):5781-6. PMID: 16574773.
      Citations: 89     Fields:    Translation:AnimalsCells
    119. Vargo-Gogola T, Heckman BM, Gunther EJ, Chodosh LA, Rosen JM. P190-B Rho GTPase-activating protein overexpression disrupts ductal morphogenesis and induces hyperplastic lesions in the developing mammary gland. Mol Endocrinol. 2006 Jun; 20(6):1391-405. PMID: 16469769.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    120. Grimm SL, Rosen JM. Stop! In the name of transforming growth factor-beta: keeping estrogen receptor-alpha-positive mammary epithelial cells from proliferating. Breast Cancer Res. 2006; 8(4):106. PMID: 16834786.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    121. Zhang M, Rosen JM. Stem cells in the etiology and treatment of cancer. Curr Opin Genet Dev. 2006 Feb; 16(1):60-4. PMID: 16377171.
      Citations: 57     Fields:    Translation:HumansCells
    122. Xian W, Schwertfeger KL, Vargo-Gogola T, Rosen JM. Pleiotropic effects of FGFR1 on cell proliferation, survival, and migration in a 3D mammary epithelial cell model. J Cell Biol. 2005 Nov 21; 171(4):663-73. PMID: 16301332.
      Citations: 72     Fields:    Translation:AnimalsCells
    123. Behbod F, Xian W, Shaw CA, Hilsenbeck SG, Tsimelzon A, Rosen JM. Transcriptional profiling of mammary gland side population cells. Stem Cells. 2006 Apr; 24(4):1065-74. PMID: 16282442.
      Citations: 17     Fields:    Translation:AnimalsCells
    124. Grimm SL, Contreras A, Barcellos-Hoff MH, Rosen JM. Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice. J Biol Chem. 2005 Oct 28; 280(43):36301-9. PMID: 16120603.
      Citations: 16     Fields:    Translation:AnimalsCells
    125. Woodward WA, Chen MS, Behbod F, Rosen JM. On mammary stem cells. J Cell Sci. 2005 Aug 15; 118(Pt 16):3585-94. PMID: 16105882.
      Citations: 103     Fields:    Translation:HumansAnimalsCells
    126. Li Y, Rosen JM. Stem/progenitor cells in mouse mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia. 2005 Jan; 10(1):17-24. PMID: 15886883.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    127. Lam MH, Rosen JM. Chk1 versus Cdc25: chking one's levels of cellular proliferation. Cell Cycle. 2004 Nov; 3(11):1355-7. PMID: 15483403.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    128. Behbod F, Rosen JM. Will cancer stem cells provide new therapeutic targets? Carcinogenesis. 2005 Apr; 26(4):703-11. PMID: 15459022.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    129. Lam MH, Liu Q, Elledge SJ, Rosen JM. Chk1 is haploinsufficient for multiple functions critical to tumor suppression. Cancer Cell. 2004 Jul; 6(1):45-59. PMID: 15261141.
      Citations: 121     Fields:    Translation:AnimalsCells
    130. Li Y, Welm B, Podsypanina K, Huang S, Chamorro M, Zhang X, Rowlands T, Egeblad M, Cowin P, Werb Z, Tan LK, Rosen JM, Varmus HE. Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15853-8. PMID: 14668450.
      Citations: 253     Fields:    Translation:AnimalsCells
    131. Freeman KW, Welm BE, Gangula RD, Rosen JM, Ittmann M, Greenberg NM, Spencer DM. Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice. Cancer Res. 2003 Dec 01; 63(23):8256-63. PMID: 14678983.
      Citations: 30     Fields:    Translation:AnimalsCells
    132. Contreras A, Hale TK, Stenoien DL, Rosen JM, Mancini MA, Herrera RE. The dynamic mobility of histone H1 is regulated by cyclin/CDK phosphorylation. Mol Cell Biol. 2003 Dec; 23(23):8626-36. PMID: 14612406.
      Citations: 66     Fields:    Translation:HumansCells
    133. Hernandez I, Maddison LA, Wei Y, DeMayo F, Petras T, Li B, Gingrich JR, Rosen JM, Greenberg NM. Prostate-specific expression of p53(R172L) differentially regulates p21, Bax, and mdm2 to inhibit prostate cancer progression and prolong survival. Mol Cancer Res. 2003 Dec; 1(14):1036-47. PMID: 14707287.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    134. Welm B, Behbod F, Goodell MA, Rosen JM. Isolation and characterization of functional mammary gland stem cells. Cell Prolif. 2003 Oct; 36 Suppl 1:17-32. PMID: 14521513.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    135. Rijnkels M, Elnitski L, Miller W, Rosen JM. Multispecies comparative analysis of a mammalian-specific genomic domain encoding secretory proteins. Genomics. 2003 Oct; 82(4):417-32. PMID: 13679022.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    136. Freeman KW, Gangula RD, Welm BE, Ozen M, Foster BA, Rosen JM, Ittmann M, Greenberg NM, Spencer DM. Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation. Cancer Res. 2003 Oct 01; 63(19):6237-43. PMID: 14559809.
      Citations: 32     Fields:    Translation:AnimalsCells
    137. Rosen JM. Striking it rich by data mining. Cell. 2003 Aug 08; 114(3):271-2. PMID: 12914689.
      Citations:    Fields:    Translation:Humans
    138. Ginger MR, Rosen JM. Pregnancy-induced changes in cell-fate in the mammary gland. Breast Cancer Res. 2003; 5(4):192-7. PMID: 12817990.
      Citations: 17     Fields:    Translation:Animals
    139. Grimm SL, Rosen JM. The role of C/EBPbeta in mammary gland development and breast cancer. J Mammary Gland Biol Neoplasia. 2003 Apr; 8(2):191-204. PMID: 14635794.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    140. Rosen JM. Transcription factors. J Mammary Gland Biol Neoplasia. 2003 Apr; 8(2):143-4. PMID: 14635790.
      Citations:    Fields:    Translation:HumansAnimals
    141. Pownall ME, Welm BE, Freeman KW, Spencer DM, Rosen JM, Isaacs HV. An inducible system for the study of FGF signalling in early amphibian development. Dev Biol. 2003 Apr 01; 256(1):89-99. PMID: 12654294.
      Citations: 12     Fields:    Translation:AnimalsCells
    142. Tepera SB, McCrea PD, Rosen JM. A beta-catenin survival signal is required for normal lobular development in the mammary gland. J Cell Sci. 2003 Mar 15; 116(Pt 6):1137-49. PMID: 12584256.
      Citations: 47     Fields:    Translation:AnimalsCells
    143. Chakravarty G, Hadsell D, Buitrago W, Settleman J, Rosen JM. p190-B RhoGAP regulates mammary ductal morphogenesis. Mol Endocrinol. 2003 Jun; 17(6):1054-65. PMID: 12637587.
      Citations: 27     Fields:    Translation:AnimalsCells
    144. Kabotyanski EB, Rosen JM. Signal transduction pathways regulated by prolactin and Src result in different conformations of activated Stat5b. J Biol Chem. 2003 May 09; 278(19):17218-27. PMID: 12621061.
      Citations: 15     Fields:    Translation:HumansCells
    145. Medina D, Kittrell FS, Shepard A, Contreras A, Rosen JM, Lydon J. Hormone dependence in premalignant mammary progression. Cancer Res. 2003 Mar 01; 63(5):1067-72. PMID: 12615724.
      Citations: 37     Fields:    Translation:Animals
    146. Rosen JM. Hormone receptor patterning plays a critical role in normal lobuloalveolar development and breast cancer progression. Breast Dis. 2003; 18:3-9. PMID: 15687684.
      Citations: 17     Fields:    
    147. Grimm SL, Seagroves TN, Kabotyanski EB, Hovey RC, Vonderhaar BK, Lydon JP, Miyoshi K, Hennighausen L, Ormandy CJ, Lee AV, Stull MA, Wood TL, Rosen JM. Disruption of steroid and prolactin receptor patterning in the mammary gland correlates with a block in lobuloalveolar development. Mol Endocrinol. 2002 Dec; 16(12):2675-91. PMID: 12456789.
      Citations: 51     Fields:    Translation:AnimalsCells
    148. Kingsley-Kallesen M, Mukhopadhyay SS, Wyszomierski SL, Schanler S, Schütz G, Rosen JM. The mineralocorticoid receptor may compensate for the loss of the glucocorticoid receptor at specific stages of mammary gland development. Mol Endocrinol. 2002 Sep; 16(9):2008-18. PMID: 12198239.
      Citations: 16     Fields:    Translation:Animals
    149. Welm BE, Freeman KW, Chen M, Contreras A, Spencer DM, Rosen JM. Inducible dimerization of FGFR1: development of a mouse model to analyze progressive transformation of the mammary gland. J Cell Biol. 2002 May 13; 157(4):703-14. PMID: 12011115.
      Citations: 61     Fields:    Translation:AnimalsCells
    150. Welm BE, Tepera SB, Venezia T, Graubert TA, Rosen JM, Goodell MA. Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol. 2002 May 01; 245(1):42-56. PMID: 11969254.
      Citations: 196     Fields:    Translation:AnimalsCells
    151. Shillingford JM, Miyoshi K, Robinson GW, Grimm SL, Rosen JM, Neubauer H, Pfeffer K, Hennighausen L. Jak2 is an essential tyrosine kinase involved in pregnancy-mediated development of mammary secretory epithelium. Mol Endocrinol. 2002 Mar; 16(3):563-70. PMID: 11875116.
      Citations: 42     Fields:    Translation:AnimalsCells
    152. Medina D, Sivaraman L, Hilsenbeck SG, Conneely O, Ginger M, Rosen J, Omalle BW. Mechanisms of hormonal prevention of breast cancer. Ann N Y Acad Sci. 2001 Dec; 952:23-35. PMID: 11795441.
      Citations: 23     Fields:    Translation:HumansAnimals
    153. Miyoshi K, Shillingford JM, Smith GH, Grimm SL, Wagner KU, Oka T, Rosen JM, Robinson GW, Hennighausen L. Signal transducer and activator of transcription (Stat) 5 controls the proliferation and differentiation of mammary alveolar epithelium. J Cell Biol. 2001 Nov 12; 155(4):531-42. PMID: 11706048.
      Citations: 110     Fields:    Translation:AnimalsCells
    154. Wyszomierski SL, Rosen JM. Cooperative effects of STAT5 (signal transducer and activator of transcription 5) and C/EBPbeta (CCAAT/enhancer-binding protein-beta) on beta-casein gene transcription are mediated by the glucocorticoid receptor. Mol Endocrinol. 2001 Feb; 15(2):228-40. PMID: 11158330.
      Citations: 38     Fields:    Translation:AnimalsCells
    155. Wyszomierski SL, Yeh J, Rosen JM. Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation. Mol Endocrinol. 1999 Feb; 13(2):330-43. PMID: 9973262.
      Citations: 32     Fields:    Translation:AnimalsCells
    156. Li B, Murphy KL, Laucirica R, Kittrell F, Medina D, Rosen JM. A transgenic mouse model for mammary carcinogenesis. Oncogene. 1998 Feb 26; 16(8):997-1007. PMID: 9519874.
      Citations: 25     Fields:    Translation:AnimalsCells
    157. Rosen JM, Zahnow C, Kazansky A, Raught B. Composite response elements mediate hormonal and developmental regulation of milk protein gene expression. Biochem Soc Symp. 1998; 63:101-13. PMID: 9513715.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    158. Humphreys RC, Lydon JP, O'Malley BW, Rosen JM. Use of PRKO mice to study the role of progesterone in mammary gland development. J Mammary Gland Biol Neoplasia. 1997 Oct; 2(4):343-54. PMID: 10935022.
      Citations: 30     Fields:    Translation:Animals
    159. Li B, Rosen JM, McMenamin-Balano J, Muller WJ, Perkins AS. neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice. Mol Cell Biol. 1997 Jun; 17(6):3155-63. PMID: 9154814.
      Citations: 39     Fields:    Translation:Animals
    160. Rosen JM, Li S, Raught B, Hadsell D. The mammary gland as a bioreactor: factors regulating the efficient expression of milk protein-based transgenes. Am J Clin Nutr. 1996 Apr; 63(4):627S-32S. PMID: 8599330.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    161. Yarus S, Hadsell D, Rosen JM. Engineering transgenes for use in the mammary gland. Genet Eng (N Y). 1996; 18:57-81. PMID: 8785127.
      Citations: 3     Fields:    Translation:HumansAnimals
    162. Rosen JM, Humphreys R, Krnacik S, Juo P, Raught B. The regulation of mammary gland development by hormones, growth factors, and oncogenes. Prog Clin Biol Res. 1994; 387:95-111. PMID: 7972261.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    163. Greenberg NM, Wolfe J, Rosen JM. Casein gene expression: from transfection to transgenics. Cancer Treat Res. 1992; 61:379-97. PMID: 1360241.
      Citations: 1     Fields:    Translation:AnimalsCells
    164. Brown TL, Rosen JM. Isolation and characterization of milk protein nuclear RNAs in rat mammary gland. Anal Biochem. 1986 Mar; 153(2):211-20. PMID: 2871772.
      Citations:    Fields:    Translation:AnimalsCells
    165. Yu-Lee LY, Richter-Mann L, Couch CH, Stewart AF, Mackinlay AG, Rosen JM. Evolution of the casein multigene family: conserved sequences in the 5' flanking and exon regions. Nucleic Acids Res. 1986 Feb 25; 14(4):1883-902. PMID: 3952000.
      Citations: 26     Fields:    Translation:AnimalsCells
    166. Rosen JM, Jones WK, Rodgers JR, Compton JG, Bisbee CA, David-Inouye Y, Yu-Lee LY. Regulatory sequences involved in the hormonal control of casein gene expression. Ann N Y Acad Sci. 1986; 464:87-99. PMID: 3014951.
      Citations: 3     Fields:    Translation:AnimalsCells
    167. Rosen JM, Rodgers JR, Couch CH, Bisbee CA, David-Inouye Y, Campbell SM, Yu-Lee LY. Multihormonal regulation of milk protein gene expression. Ann N Y Acad Sci. 1986; 478:63-76. PMID: 3541754.
      Citations: 8     Fields:    Translation:AnimalsCells
    168. Johnson ML, Levy J, Rosen JM. Maintenance of milk protein gene expression in a subpopulation of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinoma cells grown on attached collagen gels. In Vitro Cell Dev Biol. 1985 Aug; 21(8):439-44. PMID: 3928590.
      Citations:    Fields:    Translation:AnimalsCells
    169. Jones WK, Yu-Lee LY, Clift SM, Brown TL, Rosen JM. The rat casein multigene family. Fine structure and evolution of the beta-casein gene. J Biol Chem. 1985 Jun 10; 260(11):7042-50. PMID: 3997858.
      Citations: 30     Fields:    Translation:AnimalsCells
    170. Rodgers JR, Johnson ML, Rosen JM. Measurement of mRNA concentration and mRNA half-life as a function of hormonal treatment. Methods Enzymol. 1985; 109:572-92. PMID: 3838791.
      Citations: 18     Fields:    Translation:AnimalsCells
    171. Campbell SM, Rosen JM, Hennighausen LG, Strech-Jurk U, Sippel AE. Comparison of the whey acidic protein genes of the rat and mouse. Nucleic Acids Res. 1984 Nov 26; 12(22):8685-97. PMID: 6095207.
      Citations: 42     Fields:    Translation:AnimalsCells
    172. Yu-Lee LY, Rosen JM. The rat casein multigene family. I. Fine structure of the gamma-casein gene. J Biol Chem. 1983 Sep 10; 258(17):10794-804. PMID: 6309815.
      Citations: 16     Fields:    Translation:AnimalsCells
    173. Johnson ML, Levy J, Supowit SC, Yu-Lee LY, Rosen JM. Tissue- and cell-specific casein gene expression. II. Relationship to site-specific DNA methylation. J Biol Chem. 1983 Sep 10; 258(17):10805-11. PMID: 6411721.
      Citations: 7     Fields:    Translation:AnimalsCells
    174. Johnson ML, Levy J, Rosen JM. Isolation and characterization of casein-producing and -nonproducing cell populations from 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinomas. Cancer Res. 1983 May; 43(5):2199-209. PMID: 6187446.
      Citations: 2     Fields:    Translation:AnimalsCells
    175. Hobbs AA, Rosen JM. Sequence of rat alpha- and gamma-casein mRNAs: evolutionary comparison of the calcium-dependent rat casein multigene family. Nucleic Acids Res. 1982 Dec 20; 10(24):8079-98. PMID: 6298707.
      Citations: 15     Fields:    Translation:AnimalsCells
    176. Hennighausen LG, Sippel AE, Hobbs AA, Rosen JM. Comparative sequence analysis of the mRNAs coding for mouse and rat whey protein. Nucleic Acids Res. 1982 Jun 25; 10(12):3733-44. PMID: 6896749.
      Citations: 15     Fields:    Translation:AnimalsCells
    177. Blackburn DE, Hobbs AA, Rosen JM. Rat beta casein cDNA: sequence analysis and evolutionary comparisons. Nucleic Acids Res. 1982 Apr 10; 10(7):2295-307. PMID: 6283475.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    178. Hobbs AA, Richards DA, Kessler DJ, Rosen JM. Complex hormonal regulation of rat casein gene expression. J Biol Chem. 1982 Apr 10; 257(7):3598-605. PMID: 6895895.
      Citations: 49     Fields:    Translation:AnimalsCells
    179. Supowit SC, Rosen JM. Hormonal induction of casein gene expression limited to a small subpopulation of 7,12-dimethylbenz(a)anthracene-induced mammary tumor cells. Cancer Res. 1982 Apr; 42(4):1355-60. PMID: 6800652.
      Citations: 5     Fields:    Translation:Animals
    180. Gupta P, Rosen JM, D'Eustachio P, Ruddle FH. Localization of the casein gene family to a single mouse chromosome. J Cell Biol. 1982 Apr; 93(1):199-204. PMID: 6896059.
      Citations: 28     Fields:    Translation:AnimalsCells
    181. Supowit SC, Rosen JM. Tumor-specific polyadenylated RNA's from 7,12-dimethylbenz(a)anthracene-induced mammary tumors revealed through hybridization with fractionated single-copy DNA. Cancer Res. 1981 Oct; 41(10):3827-34. PMID: 6169428.
      Citations: 2     Fields:    Translation:AnimalsCells
    182. Richards DA, Rodgers JR, Supowit SC, Rosen JM. Construction and preliminary characterization of the rat casein and alpha-lactalbumin cDNA clones. J Biol Chem. 1981 Jan 10; 256(1):526-32. PMID: 7005218.
      Citations: 15     Fields:    Translation:AnimalsCells
    183. Richards DA, Blackburn DE, Rosen JM. Restriction enzyme mapping and heteroduplex analysis of the rat milk protein cDNA clones. J Biol Chem. 1981 Jan 10; 256(1):533-8. PMID: 6256356.
      Citations: 6     Fields:    Translation:AnimalsCells
    184. Supowit SC, Rosen JM. Gene expression in normal and neoplastic mammary tissue. Biochemistry. 1980 Jul 22; 19(15):3452-60. PMID: 6157399.
      Citations: 7     Fields:    Translation:AnimalsCells
    185. Warner MR, Yau L, Rosen JM. Long term effects of perinatal injection of estrogen and progesterone on the morphological and biochemical development of the mammary gland. Endocrinology. 1980 Mar; 106(3):823-32. PMID: 7353545.
      Citations:    Fields:    Translation:AnimalsCells
    186. Matusik RJ, Rosen JM. Prolactin regulation of casein gene expression: possible mediators. Endocrinology. 1980 Jan; 106(1):252-9. PMID: 6243098.
      Citations: 4     Fields:    Translation:AnimalsCells
    187. Rosen JM, Matusik RJ, Richards DA, Gupta P, Rodgers JR. Multihormonal regulation of casein gene expression at the transcriptional and posttransciptional levels in the mammary gland. Recent Prog Horm Res. 1980; 36:157-93. PMID: 6997941.
      Citations: 14     Fields:    Translation:AnimalsCells
    188. Guyette WA, Matusik RJ, Rosen JM. Prolactin-mediated transcriptional and post-transcriptional control of casein gene expression. Cell. 1979 Aug; 17(4):1013-23. PMID: 487427.
      Citations: 119     Fields:    Translation:AnimalsCells
    189. Vonderhaar BK, Smith GH, Pauley RJ, Rosen JM, Topper YJ. Difference between mammary epithelial cells from mature virgin and primiparous mice. Cancer Res. 1978 Nov; 38(11 Pt 2):4059-65. PMID: 100213.
      Citations: 8     Fields:    Translation:Animals
    190. Pauley RJ, Rosen JM, Socher SH. Mammary tumour virus and casein gene transcription during mouse mammary development. Nature. 1978 Oct 05; 275(5679):455-7. PMID: 211437.
      Citations: 5     Fields:    Translation:AnimalsCells
    191. Matusik RJ, Rosen JM. Prolactin induction of casein mRNA in organ culture. A model system for studying peptide hormone regulation of gene expression. J Biol Chem. 1978 Apr 10; 253(7):2343-7. PMID: 632273.
      Citations: 24     Fields:    Translation:AnimalsCells
    192. Rosen JM, O'Neal DL, McHugh JE, Comstock JP. Progesterone-mediated inhibition of casein mRNA and polysomal casein synthesis in the rat mammary gland during pregnancy. Biochemistry. 1978 Jan 24; 17(2):290-7. PMID: 619992.
      Citations: 26     Fields:    Translation:AnimalsCells
    193. Rosen JM, Socher SH. Detection of casein messenger RNA in hormone-dependent mammary cancer by molecular hybridisation. Nature. 1977 Sep 01; 269(5623):83-6. PMID: 408713.
      Citations: 1     Fields:    Translation:AnimalsCells
    194. Chan L, Harris SE, Rosen JM, Means AR, O'Malley BW. Processing of nuclear heterogeneous RNA: recent developments. Life Sci. 1977 Jan 01; 20(1):1-15. PMID: 319316.
      Citations: 2     Fields:    Translation:AnimalsCells
    195. Rosen JM. Isolation and characterization of purified rat casein messenger ribonucleic acids. Biochemistry. 1976 Nov 30; 15(24):5263-71. PMID: 999806.
      Citations: 11     Fields:    Translation:AnimalsCells
    196. Rosen JM, Barker SW. Quantitation of casein messenger ribonucleic acid sequences using a specific complementary DNA hybridization probe. Biochemistry. 1976 Nov 30; 15(24):5272-80. PMID: 63286.
      Citations: 14     Fields:    Translation:AnimalsCells
    197. Rosen JM, Woo SL, Comstock JP. Regulation of casein messenger RNA during the development of the rat mammary gland. Biochemistry. 1975 Jul; 14(13):2895-903. PMID: 1148182.
      Citations: 41     Fields:    Translation:AnimalsCells
    198. Rosen JM, Chan L, Woo SL, Harris SE, Means AR, O'Malley BW. Effect of estrogen on the synthesis and processing of ovalbumin messenger RNA in the chick oviduct. Brookhaven Symp Biol. 1975 Jul; (26):320-32. PMID: 1192242.
      Citations:    Fields:    Translation:AnimalsCells
    199. Harris SE, Rosen JM, Means AR, O'Malley BW. Use of a specific probe for ovalbumin messenger RNA to quantitate estrogen-induced gene transcripts. Biochemistry. 1975 May 20; 14(10):2072-81. PMID: 50081.
      Citations: 35     Fields:    Translation:AnimalsCells
    200. Rosen JM, Woo SL, Holder JW, Means AR, O'Malley BW. Preparation and preliminary characterization of purified ovalbumin messenger RNA from the hen oviduct. Biochemistry. 1975 Jan 14; 14(1):69-78. PMID: 1109593.
      Citations: 48     Fields:    Translation:AnimalsCells
    201. Rosen JM, Harris SE, Rosenfeld GC, Liarakos CD, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. 3. Hybridization studies with (3H) messenger RNA and (3H) complementary DNA under conditions of DNA excess. Cell Differ. 1974 Jul; 3(2):103-16. PMID: 4136693.
      Citations: 5     Fields:    Translation:AnimalsCells
    202. Woo SL, Harris SE, Rosen JM, Chan L, Sperry PJ, Means AR, O'Malley BW. Use of Sepharose 4B for preparative scale fractionation of eukaryotic messenger RNA's. Prep Biochem. 1974; 4(6):555-72. PMID: 4475423.
      Citations: 4     Fields:    Translation:Animals
    203. Rosen JM, Liarakos CD, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. I. Deoxyribonucleic acid--deoxyribonucleic acid renaturation studies. Biochemistry. 1973 Jul 17; 12(15):2803-9. PMID: 4719119.
      Citations: 3     Fields:    Translation:AnimalsCells
    204. Liarakos CD, Rosen JM, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. II. Transcription of chick tritiated unique deoxyribonucleic acid as measured by hybridization in ribonucleic acid excess. Biochemistry. 1973 Jul 17; 12(15):2809-16. PMID: 4719120.
      Citations: 4     Fields:    Translation:AnimalsCells
    205. Wang JJ, Chervinsky DS, Rosen JM. Comparative biochemical studies of adriamycin and daunomycin in leukemic cells. Cancer Res. 1972 Mar; 32(3):511-5. PMID: 5061305.
      Citations: 9     Fields:    Translation:Animals
    206. Rosen JM, Fina JJ, Milholland RJ, Rosen F. Inhibitory effect of cortisol in vitro on 2-deoxyglucose uptake and RNA and protein metabolism in lymphosarcoma P1798. Cancer Res. 1972 Feb; 32(2):350-5. PMID: 5066716.
      Citations: 5     Fields:    Translation:Animals
    207. Rosen JM, Milholland RJ, Rosen F. A comparison of the effect of glucocorticoids on glucose uptake and hexokinase activity in lymphosarcoma P1798. Biochim Biophys Acta. 1970 Dec 01; 219(2):447-54. PMID: 5537126.
      Citations: 3     Fields:    Translation:Animals
    208. Rosen JM, Fina JR, Milholland J, Rosen F. Inhibition of glucose uptake in lymphosarcoma P1798 by cortisol and its relationship to the biosynthesis of deoxyribonucleic acid. J Biol Chem. 1970 Apr 25; 245(8):2074-80. PMID: 5467455.
      Citations: 7     Fields:    Translation:Animals
    209. Rosen JM, Rosen F, Milholland RJ, Nichol CA. Effects of cortisol on DNA metabolism in the sensitive and resistant lines of mouse lymphoma P1798. Cancer Res. 1970 Apr; 30(4):1129-36. PMID: 5504353.
      Citations:    Fields:    Translation:Animals
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