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JAMES E CROWE

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Radiology
DivisionRadiology
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    R29HD036311     (CROWE, JAMES E)Sep 30, 1997 - Aug 31, 2002
    NIH/NICHD
    ONTOGENY OF RSV-SPECIFIC B CELL RESPONSES IN HUMANS
    Role: Principal Investigator

    R01HD036311     (CROWE, JAMES E)Sep 30, 1997 - Aug 31, 2003
    NIH/NICHD
    ONTOGENY OF RSV-SPECIFIC B CELL RESPONSES IN HUMANS
    Role: Principal Investigator

    R21DE014039     (CROWE, JAMES E)Sep 1, 2000 - Aug 31, 2003
    NIH/NIDCR
    RESPIRATORY VIRUS NEUTRALIZATION BY INTRACELLULAR AB
    Role: Principal Investigator

    U01AI048512     (CROWE, JAMES E)Sep 15, 2000 - Aug 31, 2003
    NIH/NIAID
    HUMAN MONOCLONAL ANTIBODIES THAT NEUTRALIZE VACCINIA
    Role: Principal Investigator

    R03TW001497     (CROWE, JAMES E)Aug 15, 2002 - Jun 30, 2005
    NIH/FIC
    Epitope Specificity of RSV Nucleoprotein-Specific T Cel*
    Role: Principal Investigator

    R01AI048677     (CROWE, JAMES E)Sep 1, 2002 - Aug 31, 2006
    NIH/NIAID
    Novel methods for generation of human B cell hybridomas
    Role: Principal Investigator

    R01AI053222     (CROWE, JAMES E)Jul 1, 2003 - Jun 30, 2007
    NIH/NIAID
    Human T Cells Responses to RSV
    Role: Principal Investigator

    R01AI057661     (CROWE, JAMES E)Sep 15, 2003 - Feb 28, 2008
    NIH/NIAID
    Cell-Mediated Immune Responses to Vaccinia Viruses
    Role: Principal Investigator

    S10RR019032     (CROWE, JAMES E)Apr 1, 2004 - Mar 31, 2005
    NIH/NCRR
    High Throughput Flow Cytometry Sorter
    Role: Principal Investigator

    R01AI059597     (CROWE, JAMES E)Apr 1, 2004 - Feb 28, 2010
    NIH/NIAID
    Alphavirus-based Vaccine for Prevention of MPV Infection
    Role: Principal Investigator

    R01AI057933     (CROWE, JAMES E)Jun 15, 2004 - May 31, 2009
    NIH/NIAID
    Human Antibody Responses to Rotavirus
    Role: Principal Investigator

    PN1EY016567     (CROWE, JAMES E)Sep 30, 2004 - Jul 31, 2005
    NIH/NEI
    Immunomodulation on the Nanoscale (RMI)
    Role: Principal Investigator

    R21AG030321     (CROWE, JAMES E)Sep 30, 2007 - Jul 31, 2010
    NIH/NIA
    Respiratory Syncytial Virus Nanoparticle Vaccines
    Role: Principal Investigator

    U01AI078407     (CROWE, JAMES E)Mar 15, 2008 - Feb 28, 2013
    NIH/NIAID
    Clonal Analysis of the Human B Cell Response to HIV
    Role: Principal Investigator

    R21AI083574     (CROWE, JAMES E)Jul 22, 2009 - Jun 30, 2011
    NIH/NIAID
    Rotavirus VP6 Specific Human IgA Antibodies
    Role: Principal Investigator

    S10RR027977     (CROWE, JAMES E)Mar 4, 2010 - Mar 3, 2011
    NIH/NCRR
    Multi-Laser Flow Cytometer for Polychromatic Analysis
    Role: Principal Investigator

    T32AI089554     (CROWE, JAMES E)May 1, 2010 - Apr 30, 2015
    NIH/NIAID
    Virology Training Program
    Role: Principal Investigator

    R01AI106002     (CROWE, JAMES E)Aug 15, 2012 - Jul 31, 2016
    NIH/NIAID
    Molecular Determinants of Cross-Reactive Antibody Response to Influenza in Humans
    Role: Principal Investigator

    R21AI103834     (CROWE, JAMES E)Jun 1, 2013 - May 31, 2015
    NIH/NIAID
    Human neutralizing monoclonal antibodies for Rift Valley fever virus
    Role: Principal Investigator

    R56AI110750     (MEILER, JENS)Sep 5, 2014 - Aug 31, 2015
    NIH/NIAID
    Hybrid Methods for Prediction and Design of Novel Human Influenza Antibodies
    Role: Co-Principal Investigator

    R01AI114816     (CROWE, JAMES E)Feb 10, 2015 - Jan 31, 2020
    NIH/NIAID
    Structural and functional basis of ultra potent CHKV neutralization by human mAbs
    Role: Principal Investigator

    U19AI117905     (CROWE, JAMES E)May 1, 2015 - Apr 30, 2020
    NIH/NIAID
    Structure based design of antibodies and vaccines
    Role: Principal Investigator

    R01AI127828     (CROWE, JAMES E)Jan 1, 2017 - Dec 31, 2021
    NIH/NIAID
    Human neutralizing antibodies for Zika virus
    Role: Principal Investigator

    R01AI141661     (BUKREYEV, ALEXANDER)Nov 1, 2018 - Oct 31, 2023
    NIH/NIAID
    Epitope-Based Design and Modified RNA Platform for Bivalent Marburgvirus Vaccine
    Role: Co-Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Reif DM, Chanock SJ, Edwards KM, Crowe JE. Inappropriate Citation of Vaccine Article. J Infect Dis. 2019 Jun 03. PMID: 31158294.
      View in: PubMed
    2. Kose N, Fox JM, Sapparapu G, Bombardi R, Tennekoon RN, de Silva AD, Elbashir SM, Theisen MA, Humphris-Narayanan E, Ciaramella G, Himansu S, Diamond MS, Crowe JE. A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection. Sci Immunol. 2019 May 17; 4(35). PMID: 31101672.
      View in: PubMed
    3. Bangaru S, Lang S, Schotsaert M, Vanderven HA, Zhu X, Kose N, Bombardi R, Finn JA, Kent SJ, Gilchuk P, Gilchuk I, Turner HL, García-Sastre A, Li S, Ward AB, Wilson IA, Crowe JE. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface. Cell. 2019 May 16; 177(5):1136-1152.e18. PMID: 31100268.
      View in: PubMed
    4. Colbert MD, Flyak AI, Ogega CO, Kinchen VJ, Massaccesi G, Hernandez M, Davidson E, Doranz BJ, Cox AL, Crowe JE, Bailey JR. Broadly neutralizing antibodies targeting new sites of vulnerability in hepatitis C virus E1E2. J Virol. 2019 May 08. PMID: 31068427.
      View in: PubMed
    5. King LB, West BR, Moyer CL, Gilchuk P, Flyak A, Ilinykh PA, Bombardi R, Hui S, Huang K, Bukreyev A, Crowe JE, Saphire EO. Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun. 2019 04 17; 10(1):1788. PMID: 30996276.
      View in: PubMed
    6. Bennett MR, Bombardi RG, Kose N, Parrish EH, Nagel MB, Petit RA, Read TD, Schey KL, Thomsen IP, Skaar EP, Crowe JE. Human mAbs to Staphylococcus aureus IsdA Provide Protection Through Both Heme-Blocking and Fc-Mediated Mechanisms. J Infect Dis. 2019 Apr 08; 219(8):1264-1273. PMID: 30496483.
      View in: PubMed
    7. Crowe JE. Antibody Determinants of Influenza Immunity. J Infect Dis. 2019 Apr 08; 219(Supplement_1):S21-S29. PMID: 30715373.
      View in: PubMed
    8. Williamson LE, Flyak AI, Kose N, Bombardi R, Branchizio A, Reddy S, Davidson E, Doranz BJ, Fusco ML, Saphire EO, Halfmann PJ, Kawaoka Y, Piper AE, Glass PJ, Crowe JE. Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection. J Virol. 2019 Apr 15; 93(8). PMID: 30728263.
      View in: PubMed
    9. Dong J, Finn JA, Larsen PA, Smith TPL, Crowe JE. Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains. Front Immunol. 2019; 10:558. PMID: 30967877.
      View in: PubMed
    10. Soto C, Bombardi RG, Branchizio A, Kose N, Matta P, Sevy AM, Sinkovits RS, Gilchuk P, Finn JA, Crowe JE. High frequency of shared clonotypes in human B cell receptor repertoires. Nature. 2019 02; 566(7744):398-402. PMID: 30760926.
      View in: PubMed
    11. Engelhardt BG, Savani U, Jung DK, Powers AC, Jagasia M, Chen H, Winnick JJ, Tamboli RA, Crowe JE, Abumrad NN. New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance, Not Immunosuppressive Medications. Biol Blood Marrow Transplant. 2019 Jun; 25(6):1225-1231. PMID: 30738170.
      View in: PubMed
    12. Salazar V, Jagger BW, Mongkolsapaya J, Burgomaster KE, Dejnirattisai W, Winkler ES, Fernandez E, Nelson CA, Fremont DH, Pierson TC, Crowe JE, Screaton GR, Diamond MS. Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice. Cell Rep. 2019 Feb 05; 26(6):1585-1597.e4. PMID: 30726740.
      View in: PubMed
    13. Kimble JB, Malherbe DC, Meyer M, Gunn BM, Karim MM, Ilinykh PA, Iampietro M, Mohamed KS, Negi S, Gilchuk P, Huang K, Wolf YI, Braun W, Crowe JE, Alter G, Bukreyev A. Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine. J Virol. 2019 Feb 15; 93(4). PMID: 30518655.
      View in: PubMed
    14. Turner HL, Pallesen J, Lang S, Bangaru S, Urata S, Li S, Cottrell CA, Bowman CA, Crowe JE, Wilson IA, Ward AB. Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains. PLoS Biol. 2019 Feb; 17(2):e3000139. PMID: 30716060.
      View in: PubMed
    15. Crowe JE. Influenza Virus-Specific Human Antibody Repertoire Studies. J Immunol. 2019 Jan 15; 202(2):368-373. PMID: 30617118.
      View in: PubMed
    16. Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe JE, Rossmann MG. Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1591-1596. PMID: 30642974.
      View in: PubMed
    17. Sevy AM, Wu NC, Gilchuk IM, Parrish EH, Burger S, Yousif D, Nagel MBM, Schey KL, Wilson IA, Crowe JE, Meiler J. Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1597-1602. PMID: 30642961.
      View in: PubMed
    18. Vogt MR, Crowe JE. Current Understanding of Humoral Immunity to Enterovirus D68. J Pediatric Infect Dis Soc. 2018 Dec 26; 7(suppl_2):S49-S53. PMID: 30590621.
      View in: PubMed
    19. Chukwuma VU, Kose N, Sather DN, Sapparapu G, Falk R, King H, Singh V, Lampley R, Malherbe DC, Ditto NT, Sullivan JT, Barnes T, Doranz BJ, Labranche CC, Montefiori DC, Kalams SA, Haigwood NL, Crowe JE. Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth. PLoS One. 2018; 13(12):e0209437. PMID: 30566528.
      View in: PubMed
    20. Ilinykh PA, Graber J, Kuzmina NA, Huang K, Ksiazek TG, Crowe JE, Bukreyev A. Ebolavirus Chimerization for the Development of a Mouse Model for Screening of Bundibugyo-Specific Antibodies. J Infect Dis. 2018 Nov 22; 218(suppl_5):S418-S422. PMID: 30060231.
      View in: PubMed
    21. Gilchuk P, Mire CE, Geisbert JB, Agans KN, Deer DJ, Cross RW, Slaughter JC, Flyak AI, Mani J, Pauly MH, Velasco J, Whaley KJ, Zeitlin L, Geisbert TW, Crowe JE. Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates. J Infect Dis. 2018 Nov 22; 218(suppl_5):S565-S573. PMID: 29982718.
      View in: PubMed
    22. Wirawan M, Fibriansah G, Marzinek JK, Lim XX, Ng TS, Sim AYL, Zhang Q, Kostyuchenko VA, Shi J, Smith SA, Verma CS, Anand G, Crowe JE, Bond PJ, Lok SM. Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure. 2019 Feb 05; 27(2):253-267.e8. PMID: 30471923.
      View in: PubMed
    23. Kim AS, Austin SK, Gardner CL, Zuiani A, Reed DS, Trobaugh DW, Sun C, Basore K, Williamson LE, Crowe JE, Slifka MK, Fremont DH, Klimstra WB, Diamond MS. Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein. Nat Microbiol. 2019 01; 4(1):187-197. PMID: 30455470.
      View in: PubMed
    24. Goo L, Debbink K, Kose N, Sapparapu G, Doyle MP, Wessel AW, Richner JM, Burgomaster KE, Larman BC, Dowd KA, Diamond MS, Crowe JE, Pierson TC. A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions. Nat Microbiol. 2019 01; 4(1):71-77. PMID: 30455471.
      View in: PubMed
    25. Flyak AI, Ruiz S, Colbert MD, Luong T, Crowe JE, Bailey JR, Bjorkman PJ. HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. Cell Host Microbe. 2018 11 14; 24(5):703-716.e3. PMID: 30439340.
      View in: PubMed
    26. Kinchen VJ, Zahid MN, Flyak AI, Soliman MG, Learn GH, Wang S, Davidson E, Doranz BJ, Ray SC, Cox AL, Crowe JE, Bjorkman PJ, Shaw GM, Bailey JR. Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection. Cell Host Microbe. 2018 11 14; 24(5):717-730.e5. PMID: 30439341.
      View in: PubMed
    27. Patel A, Park DH, Davis CW, Smith TRF, Leung A, Tierney K, Bryan A, Davidson E, Yu X, Racine T, Reed C, Gorman ME, Wise MC, Elliott STC, Esquivel R, Yan J, Chen J, Muthumani K, Doranz BJ, Saphire EO, Crowe JE, Broderick KE, Kobinger GP, He S, Qiu X, Kobasa D, Humeau L, Sardesai NY, Ahmed R, Weiner DB. In Vivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model. Cell Rep. 2018 Nov 13; 25(7):1982-1993.e4. PMID: 30428362.
      View in: PubMed
    28. Tsai WY, Chen HL, Tsai JJ, Dejnirattisai W, Jumnainsong A, Mongkolsapaya J, Screaton G, Crowe JE, Wang WK. Potent Neutralizing Human Monoclonal Antibodies Preferentially Target Mature Dengue Virus Particles: Implication for Novel Strategy for Dengue Vaccine. J Virol. 2018 Dec 01; 92(23). PMID: 30185598.
      View in: PubMed
    29. Bramble MS, Hoff N, Gilchuk P, Mukadi P, Lu K, Doshi RH, Steffen I, Nicholson BP, Lipson A, Vashist N, Sinai C, Spencer D, Olinger G, Wemakoy EO, Illunga BK, Pettitt J, Logue J, Marchand J, Varughese J, Bennett RS, Jahrling P, Cavet G, Serafini T, Ollmann Saphire E, Vilain E, Muyembe-Tamfum JJ, Hensely LE, Simmons G, Crowe JE, Rimoin AW. Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infection Survivors. J Infect Dis. 2018 Nov 05; 218(12):1929-1936. PMID: 30107445.
      View in: PubMed
    30. Alvarado G, Ettayebi K, Atmar RL, Bombardi RG, Kose N, Estes MK, Crowe JE. Human Monoclonal Antibodies That Neutralize Pandemic GII.4 Noroviruses. Gastroenterology. 2018 12; 155(6):1898-1907. PMID: 30170116.
      View in: PubMed
    31. Ilinykh PA, Santos RI, Gunn BM, Kuzmina NA, Shen X, Huang K, Gilchuk P, Flyak AI, Younan P, Alter G, Crowe JE, Bukreyev A. Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap. PLoS Pathog. 2018 08; 14(8):e1007204. PMID: 30138408.
      View in: PubMed
    32. Meyer M, Yoshida A, Ramanathan P, Saphire EO, Collins PL, Crowe JE, Samal S, Bukreyev A. Antibody Repertoires to the Same Ebola Vaccine Antigen Are Differentially Affected by Vaccine Vectors. Cell Rep. 2018 Aug 14; 24(7):1816-1829. PMID: 30110638.
      View in: PubMed
    33. Kuzmina NA, Younan P, Gilchuk P, Santos RI, Flyak AI, Ilinykh PA, Huang K, Lubaki NM, Ramanathan P, Crowe JE, Bukreyev A. Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors. Cell Rep. 2018 Aug 14; 24(7):1802-1815.e5. PMID: 30110637.
      View in: PubMed
    34. Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, Krause TB, Turner HL, Murin CD, Pallesen J, Davidson E, Ahmed R, Aman MJ, Bukreyev A, Burton DR, Crowe JE, Davis CW, Georgiou G, Krammer F, Kyratsous CA, Lai JR, Nykiforuk C, Pauly MH, Rijal P, Takada A, Townsend AR, Volchkov V, Walker LM, Wang CI, Zeitlin L, Doranz BJ, Ward AB, Korber B, Kobinger GP, Andersen KG, Kawaoka Y, Alter G, Chandran K, Dye JM. Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection. Cell. 2018 08 09; 174(4):938-952.e13. PMID: 30096313.
      View in: PubMed
    35. Gunn BM, Yu WH, Karim MM, Brannan JM, Herbert AS, Wec AZ, Halfmann PJ, Fusco ML, Schendel SL, Gangavarapu K, Krause T, Qiu X, He S, Das J, Suscovich TJ, Lai J, Chandran K, Zeitlin L, Crowe JE, Lauffenburger D, Kawaoka Y, Kobinger GP, Andersen KG, Dye JM, Saphire EO, Alter G. A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus. Cell Host Microbe. 2018 08 08; 24(2):221-233.e5. PMID: 30092199.
      View in: PubMed
    36. Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe JE. Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein. Immunity. 2018 08 21; 49(2):363-374.e10. PMID: 30029854.
      View in: PubMed
    37. Bangaru S, Zhang H, Gilchuk IM, Voss TG, Irving RP, Gilchuk P, Matta P, Zhu X, Lang S, Nieusma T, Richt JA, Albrecht RA, Vanderven HA, Bombardi R, Kent SJ, Ward AB, Wilson IA, Crowe JE. A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun. 2018 07 10; 9(1):2669. PMID: 29991715.
      View in: PubMed
    38. Crowe JE. Is It Possible to Develop a "Universal" Influenza Virus Vaccine? Potential for a Universal Influenza Vaccine. Cold Spring Harb Perspect Biol. 2018 Jul 02; 10(7). PMID: 28663208.
      View in: PubMed
    39. Setliff I, McDonnell WJ, Raju N, Bombardi RG, Murji AA, Scheepers C, Ziki R, Mynhardt C, Shepherd BE, Mamchak AA, Garrett N, Karim SA, Mallal SA, Crowe JE, Morris L, Georgiev IS. Multi-Donor Longitudinal Antibody Repertoire Sequencing Reveals the Existence of Public Antibody Clonotypes in HIV-1 Infection. Cell Host Microbe. 2018 06 13; 23(6):845-854.e6. PMID: 29861170.
      View in: PubMed
    40. Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE, Doranz BJ, Fremont DH, Diamond MS. Mxra8 is a receptor for multiple arthritogenic alphaviruses. Nature. 2018 05; 557(7706):570-574. PMID: 29769725.
      View in: PubMed
    41. Flyak AI, Kuzmina N, Murin CD, Bryan C, Davidson E, Gilchuk P, Gulka CP, Ilinykh PA, Shen X, Huang K, Ramanathan P, Turner H, Fusco ML, Lampley R, Kose N, King H, Sapparapu G, Doranz BJ, Ksiazek TG, Wright DW, Saphire EO, Ward AB, Bukreyev A, Crowe JE. Broadly neutralizing antibodies from human survivors target a conserved site in the Ebola virus glycoprotein HR2-MPER region. Nat Microbiol. 2018 06; 3(6):670-677. PMID: 29736037.
      View in: PubMed
    42. Lecouturier V, Berry C, Saulnier A, Naville S, Manin C, Girerd-Chambaz Y, Crowe JE, Jackson N, Guy B. Characterization of recombinant yellow fever-dengue vaccine viruses with human monoclonal antibodies targeting key conformational epitopes. Vaccine. 2018 Apr 26. PMID: 29706291.
      View in: PubMed
    43. Fernandez E, Kose N, Edeling MA, Adhikari J, Sapparapu G, Lazarte SM, Nelson CA, Govero J, Gross ML, Fremont DH, Crowe JE, Diamond MS. Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus. MBio. 2018 02 27; 9(1). PMID: 29487230.
      View in: PubMed
    44. Mousa JJ, Binshtein E, Human S, Fong RH, Alvarado G, Doranz BJ, Moore ML, Ohi MD, Crowe JE. Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins. PLoS Pathog. 2018 02; 14(2):e1006837. PMID: 29470533.
      View in: PubMed
    45. Sevy AM, Panda S, Crowe JE, Meiler J, Vorobeychik Y. Integrating linear optimization with structural modeling to increase HIV neutralization breadth. PLoS Comput Biol. 2018 02; 14(2):e1005999. PMID: 29451898.
      View in: PubMed
    46. King LB, Fusco ML, Flyak AI, Ilinykh PA, Huang K, Gunn B, Kirchdoerfer RN, Hastie KM, Sangha AK, Meiler J, Alter G, Bukreyev A, Crowe JE, Saphire EO. The Marburgvirus-Neutralizing Human Monoclonal Antibody MR191 Targets a Conserved Site to Block Virus Receptor Binding. Cell Host Microbe. 2018 Jan 10; 23(1):101-109.e4. PMID: 29324225.
      View in: PubMed
    47. Mankowski MC, Kinchen VJ, Wasilewski LN, Flyak AI, Ray SC, Crowe JE, Bailey JR. Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):E82-E91. PMID: 29255018.
      View in: PubMed
    48. Grifoni A, Pham J, Sidney J, O'Rourke PH, Paul S, Peters B, Martini SR, de Silva AD, Ricciardi MJ, Magnani DM, Silveira CGT, Maestri A, Costa PR, de-Oliveira-Pinto LM, de Azeredo EL, Damasco PV, Phillips E, Mallal S, de Silva AM, Collins M, Durbin A, Diehl SA, Cerpas C, Balmaseda A, Kuan G, Coloma J, Harris E, Crowe JE, Stone M, Norris PJ, Busch M, Vivanco-Cid H, Cox J, Graham BS, Ledgerwood JE, Turtle L, Solomon T, Kallas EG, Watkins DI, Weiskopf D, Sette A. Prior Dengue Virus Exposure Shapes T Cell Immunity to Zika Virus in Humans. J Virol. 2017 12 15; 91(24). PMID: 28978707.
      View in: PubMed
    49. Sangha AK, Dong J, Williamson L, Hashiguchi T, Saphire EO, Crowe JE, Meiler J. Role of Non-local Interactions between CDR Loops in Binding Affinity of MR78 Antibody to Marburg Virus Glycoprotein. Structure. 2017 12 05; 25(12):1820-1828.e2. PMID: 29153506.
      View in: PubMed
    50. Matho MH, Schlossman A, Gilchuk IM, Miller G, Mikulski Z, Hupfer M, Wang J, Bitra A, Meng X, Xiang Y, Kaever T, Doukov T, Ley K, Crotty S, Peters B, Hsieh-Wilson LC, Crowe JE, Zajonc DM. Structure-function characterization of three human antibodies targeting the vaccinia virus adhesion molecule D8. J Biol Chem. 2018 01 05; 293(1):390-401. PMID: 29123031.
      View in: PubMed
    51. Lim XX, Chandramohan A, Lim XE, Crowe JE, Lok SM, Anand GS. Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-Antibody Interface. Structure. 2017 09 05; 25(9):1391-1402.e3. PMID: 28823471.
      View in: PubMed
    52. Crowe JE. Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design. Cell Host Microbe. 2017 Aug 09; 22(2):193-206. PMID: 28799905.
      View in: PubMed
    53. Broeckel R, Fox JM, Haese N, Kreklywich CN, Sukulpovi-Petty S, Legasse A, Smith PP, Denton M, Corvey C, Krishnan S, Colgin LMA, Ducore RM, Lewis AD, Axthelm MK, Mandron M, Cortez P, Rothblatt J, Rao E, Focken I, Carter K, Sapparapau G, Crowe JE, Diamond MS, Streblow DN. Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques. PLoS Negl Trop Dis. 2017 Jun; 11(6):e0005637. PMID: 28628616.
      View in: PubMed
    54. Bailey JR, Flyak AI, Cohen VJ, Li H, Wasilewski LN, Snider AE, Wang S, Learn GH, Kose N, Loerinc L, Lampley R, Cox AL, Pfaff JM, Doranz BJ, Shaw GM, Ray SC, Crowe JE. Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance. JCI Insight. 2017 May 04; 2(9). PMID: 28469084.
      View in: PubMed
    55. Crowe JE. Treating Flu with Skin of Frog. Immunity. 2017 04 18; 46(4):517-518. PMID: 28423328.
      View in: PubMed
    56. Mire CE, Geisbert JB, Borisevich V, Fenton KA, Agans KN, Flyak AI, Deer DJ, Steinkellner H, Bohorov O, Bohorova N, Goodman C, Hiatt A, Kim DH, Pauly MH, Velasco J, Whaley KJ, Crowe JE, Zeitlin L, Geisbert TW. Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody. Sci Transl Med. 2017 04 05; 9(384). PMID: 28381540.
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    226. Crowe JE. Human metapneumovirus as a major cause of human respiratory tract disease. Pediatr Infect Dis J. 2004 Nov; 23(11 Suppl):S215-21. PMID: 15577576.
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    227. Talbot TR, Stapleton JT, Brady RC, Winokur PL, Bernstein DI, Germanson T, Yoder SM, Rock MT, Crowe JE, Edwards KM. Vaccination success rate and reaction profile with diluted and undiluted smallpox vaccine: a randomized controlled trial. JAMA. 2004 Sep 08; 292(10):1205-12. PMID: 15353533.
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    229. Suara RO, Crowe JE. Effect of zinc salts on respiratory syncytial virus replication. Antimicrob Agents Chemother. 2004 Mar; 48(3):783-90. PMID: 14982765.
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    230. Williams JV, Harris PA, Tollefson SJ, Halburnt-Rush LL, Pingsterhaus JM, Edwards KM, Wright PF, Crowe JE. Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children. N Engl J Med. 2004 Jan 29; 350(5):443-50. PMID: 14749452.
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    231. Brock SC, Goldenring JR, Crowe JE. Apical recycling systems regulate directional budding of respiratory syncytial virus from polarized epithelial cells. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15143-8. PMID: 14630951.
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    232. Weitkamp JH, Kallewaard N, Kusuhara K, Bures E, Williams JV, LaFleur B, Greenberg HB, Crowe JE. Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires. J Immunol. 2003 Nov 01; 171(9):4680-8. PMID: 14568943.
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    233. Halasa NB, Whitlock JA, McCurley TL, Smith JA, Zhu Q, Ochs H, Dermody TS, Crowe JE. Fatal hemophagocytic lymphohistiocytosis associated with Epstein-Barr virus infection in a patient with a novel mutation in the signaling lymphocytic activation molecule-associated protein. Clin Infect Dis. 2003 Nov 15; 37(10):e136-41. PMID: 14583885.
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    234. Venter M, Rock M, Puren AJ, Tiemessen CT, Crowe JE. Respiratory syncytial virus nucleoprotein-specific cytotoxic T-cell epitopes in a South African population of diverse HLA types are conserved in circulating field strains. J Virol. 2003 Jul; 77(13):7319-29. PMID: 12805430.
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    235. Crowe JE, Williams JV. Immunology of viral respiratory tract infection in infancy. Paediatr Respir Rev. 2003 Jun; 4(2):112-9. PMID: 12758048.
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    236. Crowe JE, Sannella EC, Pfeiffer S, Zorn GL, Azimzadeh A, Newman R, Miller GG, Pierson RN. CD154 regulates primate humoral immunity to influenza. Am J Transplant. 2003 Jun; 3(6):680-8. PMID: 12780559.
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    237. Weitkamp JH, Kallewaard N, Kusuhara K, Feigelstock D, Feng N, Greenberg HB, Crowe JE. Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles. J Immunol Methods. 2003 Apr 01; 275(1-2):223-37. PMID: 12667686.
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    238. Rock MT, Crowe JE. Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein. Immunology. 2003 Apr; 108(4):474-80. PMID: 12667209.
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    239. Brock SC, McGraw PA, Wright PF, Crowe JE. The human polymeric immunoglobulin receptor facilitates invasion of epithelial cells by Streptococcus pneumoniae in a strain-specific and cell type-specific manner. Infect Immun. 2002 Sep; 70(9):5091-5. PMID: 12183558.
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    240. Peters TR, Jennings MT, Crowe JE. Pneumocystis carinii pneumonia in a girl with a midbrain glioma. Pediatr Hematol Oncol. 2002 Mar; 19(2):141-3. PMID: 11881789.
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