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JAMES CROWE

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Radiology
DivisionRadiology
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    R29HD036311     (CROWE, JAMES E)Sep 30, 1997 - Aug 31, 2002
    NIH/NICHD
    ONTOGENY OF RSV-SPECIFIC B CELL RESPONSES IN HUMANS
    Role: Principal Investigator

    R01HD036311     (CROWE, JAMES E)Sep 30, 1997 - Aug 31, 2003
    NIH/NICHD
    ONTOGENY OF RSV-SPECIFIC B CELL RESPONSES IN HUMANS
    Role: Principal Investigator

    R21DE014039     (CROWE, JAMES E)Sep 1, 2000 - Aug 31, 2003
    NIH/NIDCR
    RESPIRATORY VIRUS NEUTRALIZATION BY INTRACELLULAR AB
    Role: Principal Investigator

    U01AI048512     (CROWE, JAMES E)Sep 15, 2000 - Aug 31, 2003
    NIH/NIAID
    HUMAN MONOCLONAL ANTIBODIES THAT NEUTRALIZE VACCINIA
    Role: Principal Investigator

    R03TW001497     (CROWE, JAMES E)Aug 15, 2002 - Jun 30, 2005
    NIH/FIC
    Epitope Specificity of RSV Nucleoprotein-Specific T Cel*
    Role: Principal Investigator

    R01AI048677     (CROWE, JAMES E)Sep 1, 2002 - Aug 31, 2006
    NIH/NIAID
    Novel methods for generation of human B cell hybridomas
    Role: Principal Investigator

    R01AI053222     (CROWE, JAMES E)Jul 1, 2003 - Jun 30, 2007
    NIH/NIAID
    Human T Cells Responses to RSV
    Role: Principal Investigator

    R01AI057661     (CROWE, JAMES E)Sep 15, 2003 - Feb 28, 2008
    NIH/NIAID
    Cell-Mediated Immune Responses to Vaccinia Viruses
    Role: Principal Investigator

    S10RR019032     (CROWE, JAMES E)Apr 1, 2004 - Mar 31, 2005
    NIH/NCRR
    High Throughput Flow Cytometry Sorter
    Role: Principal Investigator

    R01AI059597     (CROWE, JAMES E)Apr 1, 2004 - Feb 28, 2010
    NIH/NIAID
    Alphavirus-based Vaccine for Prevention of MPV Infection
    Role: Principal Investigator

    R01AI057933     (CROWE, JAMES E)Jun 15, 2004 - May 31, 2009
    NIH/NIAID
    Human Antibody Responses to Rotavirus
    Role: Principal Investigator

    PN1EY016567     (CROWE, JAMES E)Sep 30, 2004 - Jul 31, 2005
    NIH/NEI
    Immunomodulation on the Nanoscale (RMI)
    Role: Principal Investigator

    R21AG030321     (CROWE, JAMES E)Sep 30, 2007 - Jul 31, 2010
    NIH/NIA
    Respiratory Syncytial Virus Nanoparticle Vaccines
    Role: Principal Investigator

    U01AI078407     (CROWE, JAMES E)Mar 15, 2008 - Feb 28, 2013
    NIH/NIAID
    Clonal Analysis of the Human B Cell Response to HIV
    Role: Principal Investigator

    R21AI083574     (CROWE, JAMES E)Jul 22, 2009 - Jun 30, 2011
    NIH/NIAID
    Rotavirus VP6 Specific Human IgA Antibodies
    Role: Principal Investigator

    S10RR027977     (CROWE, JAMES E)Mar 4, 2010 - Mar 3, 2011
    NIH/NCRR
    Multi-Laser Flow Cytometer for Polychromatic Analysis
    Role: Principal Investigator

    T32AI089554     (CROWE, JAMES E)May 1, 2010 - Apr 30, 2015
    NIH/NIAID
    Virology Training Program
    Role: Principal Investigator

    R01AI106002     (CROWE, JAMES E)Aug 15, 2012 - Jul 31, 2016
    NIH/NIAID
    Molecular Determinants of Cross-Reactive Antibody Response to Influenza in Humans
    Role: Principal Investigator

    R21AI103834     (CROWE, JAMES E)Jun 1, 2013 - May 31, 2015
    NIH/NIAID
    Human neutralizing monoclonal antibodies for Rift Valley fever virus
    Role: Principal Investigator

    R56AI110750     (MEILER, JENS)Sep 5, 2014 - Aug 31, 2015
    NIH/NIAID
    Hybrid Methods for Prediction and Design of Novel Human Influenza Antibodies
    Role: Co-Principal Investigator

    R01AI114816     (CROWE, JAMES E)Feb 10, 2015 - Jan 31, 2020
    NIH/NIAID
    Structural and functional basis of ultra potent CHKV neutralization by human mAbs
    Role: Principal Investigator

    U19AI117905     (CROWE, JAMES E)May 1, 2015 - Apr 30, 2020
    NIH/NIAID
    Structure based design of antibodies and vaccines
    Role: Principal Investigator

    R01AI127828     (CROWE, JAMES E)Jan 1, 2017 - Dec 31, 2021
    NIH/NIAID
    Human neutralizing antibodies for Zika virus
    Role: Principal Investigator

    R01AI141661     (BUKREYEV, ALEXANDER)Nov 1, 2018 - Oct 31, 2023
    NIH/NIAID
    Epitope-Based Design and Modified RNA Platform for Bivalent Marburgvirus Vaccine
    Role: Co-Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Soto C, Finn JA, Willis JR, Day SB, Sinkovits RS, Jones T, Schmitz S, Meiler J, Branchizio A, Crowe JE. PyIR: a scalable wrapper for processing billions of immunoglobulin and T cell receptor sequences using IgBLAST. BMC Bioinformatics. 2020 Jul 16; 21(1):314. PMID: 32677886.
      View in: PubMed
    2. Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Nkolola JP, Schäfer A, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Martinez DR, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Shrihari S, Mueller BK, Meiler J, Chandrashekar A, Mercado NB, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, McCune BT, Keeler SP, Holtzman MJ, Barouch DH, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Potently neutralizing and protective human antibodies against SARS-CoV-2. Nature. 2020 Jul 15. PMID: 32668443.
      View in: PubMed
    3. Engdahl TB, Crowe JE. Humoral Immunity to Hantavirus Infection. mSphere. 2020 Jul 15; 5(4). PMID: 32669473.
      View in: PubMed
    4. Soto C, Bombardi RG, Kozhevnikov M, Sinkovits RS, Chen EC, Branchizio A, Kose N, Day SB, Pilkinton M, Gujral M, Mallal S, Crowe JE. High Frequency of Shared Clonotypes in Human T Cell Receptor Repertoires. Cell Rep. 2020 Jul 14; 32(2):107882. PMID: 32668251.
      View in: PubMed
    5. Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Eun-Hyung Lee F, Nguyen DC, Sanz I, Martinez DR, Rothlauf PW, Bloyet LM, Whelan SPJ, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein. Nat Med. 2020 Jul 10. PMID: 32651581.
      View in: PubMed
    6. Chen EC, Rubinstein S, Soto C, Bombardi RG, Day SB, Myers L, Zaytsev A, Majedi M, Cornell RF, Crowe JE. Diverse patterns of antibody variable gene repertoire disruption in patients with amyloid light chain (AL) amyloidosis. PLoS One. 2020; 15(7):e0235713. PMID: 32634163.
      View in: PubMed
    7. Vogt MR, Fu J, Kose N, Williamson LE, Bombardi R, Setliff I, Georgiev IS, Klose T, Rossmann MG, Bochkov YA, Gern JE, Kuhn RJ, Crowe JE. Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease. Sci Immunol. 2020 Jul 03; 5(49). PMID: 32620559.
      View in: PubMed
    8. Erasmus JH, Archer J, Fuerte-Stone J, Khandhar AP, Voigt E, Granger B, Bombardi RG, Govero J, Tan Q, Durnell LA, Coler RN, Diamond MS, Crowe JE, Reed SG, Thackray LB, Carnahan RH, Van Hoeven N. Intramuscular Delivery of Replicon RNA Encoding ZIKV-117 Human Monoclonal Antibody Protects against Zika Virus Infection. Mol Ther Methods Clin Dev. 2020 Sep 11; 18:402-414. PMID: 32695842.
      View in: PubMed
    9. Zost SJ, Gilchuk P, Case JB, Binshtein E, Chen RE, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Williamson LE, Chen EC, Jones T, Day S, Myers L, Hassan AO, Kafai NM, Winkler ES, Fox JM, Steinhardt JJ, Ren K, Loo YM, Kallewaard NL, Martinez DR, Schäfer A, Gralinski LE, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals. bioRxiv. 2020 May 22. PMID: 32511409.
      View in: PubMed
    10. Zost SJ, Gilchuk P, Chen RE, Case JB, Reidy JX, Trivette A, Nargi RS, Sutton RE, Suryadevara N, Chen EC, Binshtein E, Shrihari S, Ostrowski M, Chu HY, Didier JE, MacRenaris KW, Jones T, Day S, Myers L, Lee FE, Nguyen DC, Sanz I, Martinez DR, Baric RS, Thackray LB, Diamond MS, Carnahan RH, Crowe JE. Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein. bioRxiv. 2020 May 13. PMID: 32511414.
      View in: PubMed
    11. Young E, Carnahan RH, Andrade DV, Kose N, Nargi RS, Fritch EJ, Munt JE, Doyle MP, White L, Baric TJ, Stoops M, DeSilva A, Tse LV, Martinez DR, Zhu D, Metz S, Wong MP, Espinosa DA, Montoya M, Biering SB, Sukulpolvi-Petty S, Kuan G, Balmaseda A, Diamond MS, Harris E, Crowe JE, Baric RS. Identification of Dengue Virus Serotype 3 Specific Antigenic Sites Targeted by Neutralizing Human Antibodies. Cell Host Microbe. 2020 05 13; 27(5):710-724.e7. PMID: 32407709.
      View in: PubMed
    12. Sevy AM, Gilchuk IM, Brown BP, Bozhanova NG, Nargi R, Jensen M, Meiler J, Crowe JE. Computationally Designed Cyclic Peptides Derived from an Antibody Loop Increase Breadth of Binding for Influenza Variants. Structure. 2020 May 11. PMID: 32610044.
      View in: PubMed
    13. Powell LA, Fox JM, Kose N, Kim AS, Majedi M, Bombardi R, Carnahan RH, Slaughter JC, Morrison TE, Diamond MS, Crowe JE. Human monoclonal antibodies against Ross River virus target epitopes within the E2 protein and protect against disease. PLoS Pathog. 2020 05; 16(5):e1008517. PMID: 32365139.
      View in: PubMed
    14. Buchman A, Gamez S, Li M, Antoshechkin I, Li HH, Wang HW, Chen CH, Klein MJ, Duchemin JB, Crowe JE, Paradkar PN, Akbari OS. Correction: Broad dengue neutralization in mosquitoes expressing an engineered antibody. PLoS Pathog. 2020 04; 16(4):e1008545. PMID: 32348355.
      View in: PubMed
    15. Ilinykh PA, Huang K, Santos RI, Gilchuk P, Gunn BM, Karim MM, Liang J, Fouch ME, Davidson E, Parekh DV, Kimble JB, Pietzsch CA, Meyer M, Kuzmina NA, Zeitlin L, Saphire EO, Alter G, Crowe JE, Bukreyev A. Non-neutralizing Antibodies from a Marburg Infection Survivor Mediate Protection by Fc-Effector Functions and by Enhancing Efficacy of Other Antibodies. Cell Host Microbe. 2020 06 10; 27(6):976-991.e11. PMID: 32320678.
      View in: PubMed
    16. Hirsch J, Faber BW, Crowe JE, Verstrepen B, Cornelissen G. E. coli production process yields stable dengue 1 virus-sized particles (VSPs). Vaccine. 2020 Apr 09; 38(17):3305-3312. PMID: 32197924.
      View in: PubMed
    17. Sauer MF, Sevy AM, Crowe JE, Meiler J. Multi-state design of flexible proteins predicts sequences optimal for conformational change. PLoS Comput Biol. 2020 02; 16(2):e1007339. PMID: 32032348.
      View in: PubMed
    18. Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe JE. Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity. 2020 02 18; 52(2):388-403.e12. PMID: 32023489.
      View in: PubMed
    19. Zhao H, Xu L, Bombardi R, Nargi R, Deng Z, Errico JM, Nelson CA, Dowd KA, Pierson TC, Crowe JE, Diamond MS, Fremont DH. Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge. J Exp Med. 2020 Feb 03; 217(2). PMID: 31757867.
      View in: PubMed
    20. Briney BS, Willis JR, Finn JA, McKinney BA, Crowe JE. Correction: Tissue-Specific Expressed Antibody Variable Gene Repertoires. PLoS One. 2020; 15(1):e0228412. PMID: 31978140.
      View in: PubMed
    21. Buchman A, Gamez S, Li M, Antoshechkin I, Li HH, Wang HW, Chen CH, Klein MJ, Duchemin JB, Crowe JE, Paradkar PN, Akbari OS. Broad dengue neutralization in mosquitoes expressing an engineered antibody. PLoS Pathog. 2020 01; 16(1):e1008103. PMID: 31945137.
      View in: PubMed
    22. Ho BJ, Crowe JE, Dorfman SR, Camp EA, Yusuf S, Shenoi RP. Correlation of clinical and chest radiograph findings in pediatric submersion cases. Pediatr Radiol. 2020 04; 50(4):492-500. PMID: 31897567.
      View in: PubMed
    23. Schmitz S, Soto C, Crowe JE, Meiler J. Human-likeness of antibody biologics determined by back-translation and comparison with large antibody variable gene repertoires. MAbs. 2020 Jan-Dec; 12(1):1758291. PMID: 32397786.
      View in: PubMed
    24. Sevy AM, Soto C, Bombardi RG, Meiler J, Crowe JE. Immune repertoire fingerprinting by principal component analysis reveals shared features in subject groups with common exposures. BMC Bioinformatics. 2019 Dec 04; 20(1):629. PMID: 31801472.
      View in: PubMed
    25. Zhu X, Turner HL, Lang S, McBride R, Bangaru S, Gilchuk IM, Yu W, Paulson JC, Crowe JE, Ward AB, Wilson IA. Structural Basis of Protection against H7N9 Influenza Virus by Human Anti-N9 Neuraminidase Antibodies. Cell Host Microbe. 2019 12 11; 26(6):729-738.e4. PMID: 31757767.
      View in: PubMed
    26. Gilchuk IM, Bangaru S, Gilchuk P, Irving RP, Kose N, Bombardi RG, Thornburg NJ, Creech CB, Edwards KM, Li S, Turner HL, Yu W, Zhu X, Wilson IA, Ward AB, Crowe JE. Influenza H7N9 Virus Neuraminidase-Specific Human Monoclonal Antibodies Inhibit Viral Egress and Protect from Lethal Influenza Infection in Mice. Cell Host Microbe. 2019 12 11; 26(6):715-728.e8. PMID: 31757769.
      View in: PubMed
    27. Velayutham TS, Kumar S, Zhang X, Kose N, Walker DH, Winslow G, Crowe JE, McBride JW. Ehrlichia chaffeensis Outer Membrane Protein 1-Specific Human Antibody-Mediated Immunity Is Defined by Intracellular TRIM21-Dependent Innate Immune Activation and Extracellular Neutralization. Infect Immun. 2019 12; 87(12). PMID: 31548319.
      View in: PubMed
    28. Martinez Viedma MDP, Kose N, Parham L, Balmaseda A, Kuan G, Lorenzana I, Harris E, Crowe JE, Pickett BE. Peptide arrays of three collections of human sera from patients infected with mosquito-borne viruses. F1000Res. 2019; 8:1875. PMID: 32201571.
      View in: PubMed
    29. Cable J, Srikantiah P, Crowe JE, Pulendran B, Hill A, Ginsberg A, Koff W, Mathew A, Ng T, Jansen K, Glenn G, Permar S, Wilson I, Weiner DB, Weissman D, Rappuoli R. Vaccine innovations for emerging infectious diseases-a symposium report. Ann N Y Acad Sci. 2020 02; 1462(1):14-26. PMID: 31659752.
      View in: PubMed
    30. Bennett MR, Dong J, Bombardi RG, Soto C, Parrington HM, Nargi RS, Schoeder CT, Nagel MB, Schey KL, Meiler J, Skaar EP, Crowe JE. Human VH1-69 Gene-Encoded Human Monoclonal Antibodies against Staphylococcus aureus IsdB Use at Least Three Distinct Modes of Binding To Inhibit Bacterial Growth and Pathogenesis. mBio. 2019 10 22; 10(5). PMID: 31641091.
      View in: PubMed
    31. Knight FC, Gilchuk P, Kumar A, Becker KW, Sevimli S, Jacobson ME, Suryadevara N, Wang-Bishop L, Boyd KL, Crowe JE, Joyce S, Wilson JT. Mucosal Immunization with a pH-Responsive Nanoparticle Vaccine Induces Protective CD8+ Lung-Resident Memory T Cells. ACS Nano. 2019 10 22; 13(10):10939-10960. PMID: 31553872.
      View in: PubMed
    32. Kinchen VJ, Massaccesi G, Flyak AI, Mankowski MC, Colbert MD, Osburn WO, Ray SC, Cox AL, Crowe JE, Bailey JR. Plasma deconvolution identifies broadly neutralizing antibodies associated with hepatitis C virus clearance. J Clin Invest. 2019 08 13; 129(11):4786-4796. PMID: 31408439.
      View in: PubMed
    33. Colbert MD, Flyak AI, Ogega CO, Kinchen VJ, Massaccesi G, Hernandez M, Davidson E, Doranz BJ, Cox AL, Crowe JE, Bailey JR. Broadly Neutralizing Antibodies Targeting New Sites of Vulnerability in Hepatitis C Virus E1E2. J Virol. 2019 07 15; 93(14). PMID: 31068427.
      View in: PubMed
    34. Reif DM, Chanock SJ, Edwards KM, Crowe JE. Inappropriate Citation of Vaccine Article. J Infect Dis. 2019 Jun 03. PMID: 31158294.
      View in: PubMed
    35. Kose N, Fox JM, Sapparapu G, Bombardi R, Tennekoon RN, de Silva AD, Elbashir SM, Theisen MA, Humphris-Narayanan E, Ciaramella G, Himansu S, Diamond MS, Crowe JE. A lipid-encapsulated mRNA encoding a potently neutralizing human monoclonal antibody protects against chikungunya infection. Sci Immunol. 2019 05 17; 4(35). PMID: 31101672.
      View in: PubMed
    36. Bangaru S, Lang S, Schotsaert M, Vanderven HA, Zhu X, Kose N, Bombardi R, Finn JA, Kent SJ, Gilchuk P, Gilchuk I, Turner HL, García-Sastre A, Li S, Ward AB, Wilson IA, Crowe JE. A Site of Vulnerability on the Influenza Virus Hemagglutinin Head Domain Trimer Interface. Cell. 2019 05 16; 177(5):1136-1152.e18. PMID: 31100268.
      View in: PubMed
    37. King LB, West BR, Moyer CL, Gilchuk P, Flyak A, Ilinykh PA, Bombardi R, Hui S, Huang K, Bukreyev A, Crowe JE, Saphire EO. Cross-reactive neutralizing human survivor monoclonal antibody BDBV223 targets the ebolavirus stalk. Nat Commun. 2019 04 17; 10(1):1788. PMID: 30996276.
      View in: PubMed
    38. Bennett MR, Bombardi RG, Kose N, Parrish EH, Nagel MB, Petit RA, Read TD, Schey KL, Thomsen IP, Skaar EP, Crowe JE. Human mAbs to Staphylococcus aureus IsdA Provide Protection Through Both Heme-Blocking and Fc-Mediated Mechanisms. J Infect Dis. 2019 04 08; 219(8):1264-1273. PMID: 30496483.
      View in: PubMed
    39. Crowe JE. Antibody Determinants of Influenza Immunity. J Infect Dis. 2019 04 08; 219(Suppl_1):S21-S29. PMID: 30715373.
      View in: PubMed
    40. Williamson LE, Flyak AI, Kose N, Bombardi R, Branchizio A, Reddy S, Davidson E, Doranz BJ, Fusco ML, Saphire EO, Halfmann PJ, Kawaoka Y, Piper AE, Glass PJ, Crowe JE. Early Human B Cell Response to Ebola Virus in Four U.S. Survivors of Infection. J Virol. 2019 04 15; 93(8). PMID: 30728263.
      View in: PubMed
    41. Dong J, Finn JA, Larsen PA, Smith TPL, Crowe JE. Structural Diversity of Ultralong CDRH3s in Seven Bovine Antibody Heavy Chains. Front Immunol. 2019; 10:558. PMID: 30967877.
      View in: PubMed
    42. Soto C, Bombardi RG, Branchizio A, Kose N, Matta P, Sevy AM, Sinkovits RS, Gilchuk P, Finn JA, Crowe JE. High frequency of shared clonotypes in human B cell receptor repertoires. Nature. 2019 02; 566(7744):398-402. PMID: 30760926.
      View in: PubMed
    43. Engelhardt BG, Savani U, Jung DK, Powers AC, Jagasia M, Chen H, Winnick JJ, Tamboli RA, Crowe JE, Abumrad NN. New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance, Not Immunosuppressive Medications. Biol Blood Marrow Transplant. 2019 06; 25(6):1225-1231. PMID: 30738170.
      View in: PubMed
    44. Salazar V, Jagger BW, Mongkolsapaya J, Burgomaster KE, Dejnirattisai W, Winkler ES, Fernandez E, Nelson CA, Fremont DH, Pierson TC, Crowe JE, Screaton GR, Diamond MS. Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice. Cell Rep. 2019 02 05; 26(6):1585-1597.e4. PMID: 30726740.
      View in: PubMed
    45. Kimble JB, Malherbe DC, Meyer M, Gunn BM, Karim MM, Ilinykh PA, Iampietro M, Mohamed KS, Negi S, Gilchuk P, Huang K, Wolf YI, Braun W, Crowe JE, Alter G, Bukreyev A. Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine. J Virol. 2019 02 15; 93(4). PMID: 30518655.
      View in: PubMed
    46. Turner HL, Pallesen J, Lang S, Bangaru S, Urata S, Li S, Cottrell CA, Bowman CA, Crowe JE, Wilson IA, Ward AB. Potent anti-influenza H7 human monoclonal antibody induces separation of hemagglutinin receptor-binding head domains. PLoS Biol. 2019 02; 17(2):e3000139. PMID: 30716060.
      View in: PubMed
    47. Crowe JE. Influenza Virus-Specific Human Antibody Repertoire Studies. J Immunol. 2019 01 15; 202(2):368-373. PMID: 30617118.
      View in: PubMed
    48. Long F, Doyle M, Fernandez E, Miller AS, Klose T, Sevvana M, Bryan A, Davidson E, Doranz BJ, Kuhn RJ, Diamond MS, Crowe JE, Rossmann MG. Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1591-1596. PMID: 30642974.
      View in: PubMed
    49. Sevy AM, Wu NC, Gilchuk IM, Parrish EH, Burger S, Yousif D, Nagel MBM, Schey KL, Wilson IA, Crowe JE, Meiler J. Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses. Proc Natl Acad Sci U S A. 2019 01 29; 116(5):1597-1602. PMID: 30642961.
      View in: PubMed
    50. Vogt MR, Crowe JE. Current Understanding of Humoral Immunity to Enterovirus D68. J Pediatric Infect Dis Soc. 2018 Dec 26; 7(suppl_2):S49-S53. PMID: 30590621.
      View in: PubMed
    51. Chukwuma VU, Kose N, Sather DN, Sapparapu G, Falk R, King H, Singh V, Lampley R, Malherbe DC, Ditto NT, Sullivan JT, Barnes T, Doranz BJ, Labranche CC, Montefiori DC, Kalams SA, Haigwood NL, Crowe JE. Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth. PLoS One. 2018; 13(12):e0209437. PMID: 30566528.
      View in: PubMed
    52. Ilinykh PA, Graber J, Kuzmina NA, Huang K, Ksiazek TG, Crowe JE, Bukreyev A. Ebolavirus Chimerization for the Development of a Mouse Model for Screening of Bundibugyo-Specific Antibodies. J Infect Dis. 2018 11 22; 218(suppl_5):S418-S422. PMID: 30060231.
      View in: PubMed
    53. Gilchuk P, Mire CE, Geisbert JB, Agans KN, Deer DJ, Cross RW, Slaughter JC, Flyak AI, Mani J, Pauly MH, Velasco J, Whaley KJ, Zeitlin L, Geisbert TW, Crowe JE. Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates. J Infect Dis. 2018 11 22; 218(suppl_5):S565-S573. PMID: 29982718.
      View in: PubMed
    54. Wirawan M, Fibriansah G, Marzinek JK, Lim XX, Ng TS, Sim AYL, Zhang Q, Kostyuchenko VA, Shi J, Smith SA, Verma CS, Anand G, Crowe JE, Bond PJ, Lok SM. Mechanism of Enhanced Immature Dengue Virus Attachment to Endosomal Membrane Induced by prM Antibody. Structure. 2019 02 05; 27(2):253-267.e8. PMID: 30471923.
      View in: PubMed
    55. Kim AS, Austin SK, Gardner CL, Zuiani A, Reed DS, Trobaugh DW, Sun C, Basore K, Williamson LE, Crowe JE, Slifka MK, Fremont DH, Klimstra WB, Diamond MS. Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein. Nat Microbiol. 2019 01; 4(1):187-197. PMID: 30455470.
      View in: PubMed
    56. Goo L, Debbink K, Kose N, Sapparapu G, Doyle MP, Wessel AW, Richner JM, Burgomaster KE, Larman BC, Dowd KA, Diamond MS, Crowe JE, Pierson TC. A protective human monoclonal antibody targeting the West Nile virus E protein preferentially recognizes mature virions. Nat Microbiol. 2019 01; 4(1):71-77. PMID: 30455471.
      View in: PubMed
    57. Flyak AI, Ruiz S, Colbert MD, Luong T, Crowe JE, Bailey JR, Bjorkman PJ. HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. Cell Host Microbe. 2018 11 14; 24(5):703-716.e3. PMID: 30439340.
      View in: PubMed
    58. Kinchen VJ, Zahid MN, Flyak AI, Soliman MG, Learn GH, Wang S, Davidson E, Doranz BJ, Ray SC, Cox AL, Crowe JE, Bjorkman PJ, Shaw GM, Bailey JR. Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection. Cell Host Microbe. 2018 11 14; 24(5):717-730.e5. PMID: 30439341.
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    269. Weitkamp JH, Kallewaard N, Kusuhara K, Feigelstock D, Feng N, Greenberg HB, Crowe JE. Generation of recombinant human monoclonal antibodies to rotavirus from single antigen-specific B cells selected with fluorescent virus-like particles. J Immunol Methods. 2003 Apr 01; 275(1-2):223-37. PMID: 12667686.
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    270. Rock MT, Crowe JE. Identification of a novel human leucocyte antigen-A*01-restricted cytotoxic T-lymphocyte epitope in the respiratory syncytial virus fusion protein. Immunology. 2003 Apr; 108(4):474-80. PMID: 12667209.
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    271. Brock SC, McGraw PA, Wright PF, Crowe JE. The human polymeric immunoglobulin receptor facilitates invasion of epithelial cells by Streptococcus pneumoniae in a strain-specific and cell type-specific manner. Infect Immun. 2002 Sep; 70(9):5091-5. PMID: 12183558.
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    272. Peters TR, Jennings MT, Crowe JE. Pneumocystis carinii pneumonia in a girl with a midbrain glioma. Pediatr Hematol Oncol. 2002 Mar; 19(2):141-3. PMID: 11881789.
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