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HEINRICH TAEGTMEYER

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
DivisionMedicine-Endocrinology
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    Other Positions
    TitleAdjunct Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pediatrics
    DivisionPediatrics-Nutrition


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Li J, Minczuk K, Massey JC, Howell NL, Roy RJ, Paul S, Patrie JT, Kramer CM, Epstein FH, Carey RM, Taegtmeyer H, Keller SR, Kundu BK. Metformin Improves Cardiac Metabolism and Function, and Prevents Left Ventricular Hypertrophy in Spontaneously Hypertensive Rats. J Am Heart Assoc. 2020 Apr 07; 9(7):e015154. PMID: 32248762.
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    2. Hamidi V, Riggs K, Zhu L, Bermudez Saint Andre K, Westby C, Coverdale S, Dursteler A, Wang H, Miller Iii C, Taegtmeyer H, Gutierrez AD. Acute Exenatide Therapy Attenuates Postprandial Vasodilation in Humans with Prediabetes: A Randomized Controlled Trial. Metab Syndr Relat Disord. 2020 Jun; 18(5):225-233. PMID: 32228379.
      View in: PubMed
    3. Taegtmeyer H, Dasgupta P. Chronos and Kairos in Lockstep: Thoughts on the Enduring Productivity of Cardiovascular Investigators. Circulation. 2019 11 19; 140(21):1687-1689. PMID: 31738595.
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    4. Karlstaedt A, Khanna R, Thangam M, Taegtmeyer H. Glucose 6-Phosphate Accumulates via Phosphoglucose Isomerase Inhibition in Heart Muscle. Circ Res. 2020 01 03; 126(1):60-74. PMID: 31698999.
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    5. Glatz JFC, Nabben M, Young ME, Schulze PC, Taegtmeyer H, Luiken JJFP. Re-balancing cellular energy substrate metabolism to mend the failing heart. Biochim Biophys Acta Mol Basis Dis. 2020 May 01; 1866(5):165579. PMID: 31678200.
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    6. Koutroumpakis E, Jozwik B, Aguilar D, Taegtmeyer H. Strategies of Unloading the Failing Heart from Metabolic Stress. Am J Med. 2020 03; 133(3):290-296. PMID: 31520618.
      View in: PubMed
    7. Verma N, Liu M, Ly H, Loria A, Campbell KS, Bush H, Kern PA, Jose PA, Taegtmeyer H, Bers DM, Despa S, Goldstein LB, Murray AJ, Despa F. Diabetic microcirculatory disturbances and pathologic erythropoiesis are provoked by deposition of amyloid-forming amylin in red blood cells and capillaries. Kidney Int. 2020 01; 97(1):143-155. PMID: 31739987.
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    8. Hou X, Chen G, Bracamonte-Baran W, Choi HS, Diny NL, Sung J, Hughes D, Won T, Wood MK, Talor MV, Hackam DJ, Klingel K, Davogustto G, Taegtmeyer H, Coppens I, Barin JG, Ciháková D. The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis. Cell Rep. 2019 07 02; 28(1):172-189.e7. PMID: 31269438.
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    9. Bracamonte-Baran W, Chen G, Hou X, Talor MV, Choi HS, Davogustto G, Taegtmeyer H, Sung J, Hackam DJ, Nauen D, Ciháková D. Non-cytotoxic Cardiac Innate Lymphoid Cells Are a Resident and Quiescent Type 2-Commited Population. Front Immunol. 2019; 10:634. PMID: 30984196.
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    10. Li J, Kemp BA, Howell NL, Massey J, Minczuk K, Huang Q, Chordia MD, Roy RJ, Patrie JT, Davogustto GE, Kramer CM, Epstein FH, Carey RM, Taegtmeyer H, Keller SR, Kundu BK. Metabolic Changes in Spontaneously Hypertensive Rat Hearts Precede Cardiac Dysfunction and Left Ventricular Hypertrophy. J Am Heart Assoc. 2019 02 19; 8(4):e010926. PMID: 30764689.
      View in: PubMed
    11. Maack C, Lehrke M, Backs J, Heinzel FR, Hulot JS, Marx N, Paulus WJ, Rossignol P, Taegtmeyer H, Bauersachs J, Bayes-Genis A, Brutsaert D, Bugger H, Clarke K, Cosentino F, De Keulenaer G, Dei Cas A, González A, Huelsmann M, Iaccarino G, Lunde IG, Lyon AR, Pollesello P, Rena G, Riksen NP, Rosano G, Staels B, van Laake LW, Wanner C, Farmakis D, Filippatos G, Ruschitzka F, Seferovic P, de Boer RA, Heymans S. Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology. Eur Heart J. 2018 12 21; 39(48):4243-4254. PMID: 30295797.
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    12. Taegtmeyer H. Maternal-Fetal Parabiosis in Obesity Exposes Unexpected Roles for Cardiac Metabolism. JACC Cardiovasc Imaging. 2018 12; 11(12):1756-1757. PMID: 30343080.
      View in: PubMed
    13. Eblimit Z, Thevananther S, Karpen SJ, Taegtmeyer H, Moore DD, Adorini L, Penny DJ, Desai MS. TGR5 activation induces cytoprotective changes in the heart and improves myocardial adaptability to physiologic, inotropic, and pressure-induced stress in mice. Cardiovasc Ther. 2018 Oct; 36(5):e12462. PMID: 30070769.
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    14. Nam DH, Kim E, Benham A, Park HK, Soibam B, Taffet GE, Kaelber JT, Suh JH, Taegtmeyer H, Entman ML, Reineke EL. Transient activation of AMPK preceding left ventricular pressure overload reduces adverse remodeling and preserves left ventricular function. FASEB J. 2019 01; 33(1):711-721. PMID: 30024790.
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    15. Chen G, Bracamonte-Baran W, Diny NL, Hou X, Talor MV, Fu K, Liu Y, Davogustto G, Vasquez H, Taegtmeyer H, Frazier OH, Waisman A, Conway SJ, Wan F, Ciháková D. Sca-1+ cardiac fibroblasts promote development of heart failure. Eur J Immunol. 2018 09; 48(9):1522-1538. PMID: 29953616.
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    16. Karlstaedt A, Schiffer W, Taegtmeyer H. Actionable Metabolic Pathways in Heart Failure and Cancer-Lessons From Cancer Cell Metabolism. Front Cardiovasc Med. 2018; 5:71. PMID: 29971237.
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    17. Stoll BJ, Taegtmeyer H. Challenges for Today's Pediatric Physician-Scientists. JAMA Pediatr. 2018 03 01; 172(3):220-221. PMID: 29340573.
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    18. Taegtmeyer H, Karlstaedt A. Letter by Taegtmeyer and Karlstaedt Regarding Article, "Lower Risk of Heart Failure and Death in Patients Initiated on Sodium-Glucose Cotransporter-2 Inhibitors Versus Other Glucose-Lowering Drugs: The CVD-REAL Study (Comparative Effectiveness of Cardiovascular Outcomes in New Users of Sodium-Glucose Cotransporter-2 Inhibitors)". Circulation. 2018 02 27; 137(9):986-987. PMID: 29483178.
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    19. Brewer RA, Collins HE, Berry RD, Brahma MK, Tirado BA, Peliciari-Garcia RA, Stanley HL, Wende AR, Taegtmeyer H, Rajasekaran NS, Darley-Usmar V, Zhang J, Frank SJ, Chatham JC, Young ME. Temporal partitioning of adaptive responses of the murine heart to fasting. Life Sci. 2018 Mar 15; 197:30-39. PMID: 29410090.
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    20. Brookes PS, Taegtmeyer H. Metabolism: A Direct Link Between Cardiac Structure and Function. Circulation. 2017 11 28; 136(22):2158-2161. PMID: 29180494.
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    21. Garcia MI, Karlstaedt A, Chen JJ, Amione-Guerra J, Youker KA, Taegtmeyer H, Boehning D. Functionally redundant control of cardiac hypertrophic signaling by inositol 1,4,5-trisphosphate receptors. J Mol Cell Cardiol. 2017 11; 112:95-103. PMID: 28923351.
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    22. McGinnis GR, Tang Y, Brewer RA, Brahma MK, Stanley HL, Shanmugam G, Rajasekaran NS, Rowe GC, Frank SJ, Wende AR, Abel ED, Taegtmeyer H, Litovsky S, Darley-Usmar V, Zhang J, Chatham JC, Young ME. Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart. J Mol Cell Cardiol. 2017 09; 110:80-95. PMID: 28736261.
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    23. Rowlett VW, Mallampalli VKPS, Karlstaedt A, Dowhan W, Taegtmeyer H, Margolin W, Vitrac H. Impact of Membrane Phospholipid Alterations in Escherichia coli on Cellular Function and Bacterial Stress Adaptation. J Bacteriol. 2017 07 01; 199(13). PMID: 28439040.
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    24. Algahim MF, Taegtmeyer H. Comment on Gastaldelli et al. Short-term Effects of Laparoscopic Adjustable Gastric Banding Versus Roux-en-Y Gastric Bypass. Diabetes Care 2016;39:1925-1931. Diabetes Care. 2017 04; 40(4):e49. PMID: 28325805.
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    25. Taegtmeyer H, Karlstaedt A, Rees ML, Davogustto G. Oncometabolic Tracks in the Heart. Circ Res. 2017 01 20; 120(2):267-269. PMID: 28104766.
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    26. Vitrac H, MacLean DM, Karlstaedt A, Taegtmeyer H, Jayaraman V, Bogdanov M, Dowhan W. Dynamic Lipid-dependent Modulation of Protein Topology by Post-translational Phosphorylation. J Biol Chem. 2017 02 03; 292(5):1613-1624. PMID: 27974465.
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    27. Bux AS, Lindsey ML, Vasquez HG, Taegtmeyer H, Harmancey R. Glucose regulates the intrinsic inflammatory response of the heart to surgically induced hypothermic ischemic arrest and reperfusion. Physiol Genomics. 2017 01 01; 49(1):37-52. PMID: 27940566.
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    28. Desai MS, Mathur B, Eblimit Z, Vasquez H, Taegtmeyer H, Karpen SJ, Penny DJ, Moore DD, Anakk S. Bile acid excess induces cardiomyopathy and metabolic dysfunctions in the heart. Hepatology. 2017 01; 65(1):189-201. PMID: 27774647.
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    29. Taegtmeyer H, Lam T, Davogustto G. Cardiac Metabolism in Perspective. Compr Physiol. 2016 09 15; 6(4):1675-1699. PMID: 27783856.
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    30. Karlstaedt A, Zhang X, Vitrac H, Harmancey R, Vasquez H, Wang JH, Goodell MA, Taegtmeyer H. Oncometabolite d-2-hydroxyglutarate impairs a-ketoglutarate dehydrogenase and contractile function in rodent heart. Proc Natl Acad Sci U S A. 2016 09 13; 113(37):10436-41. PMID: 27582470.
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    31. Taegtmeyer H. Failing Heart and Starving Brain: Ketone Bodies to the Rescue. Circulation. 2016 Jul 26; 134(4):265-6. PMID: 27462050.
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    32. Karlstaedt A, Taegtmeyer H. Letter by Karlstaedt and Taegtmeyer Regarding Article, "Loss of Adult Cardiac Myocyte GSK-3 Leads to Mitotic Catastrophe Resulting in Fatal Dilated Cardiomyopathy". Circ Res. 2016 07 08; 119(2):e28. PMID: 27390339.
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    33. Taegtmeyer H, Young ME, Lopaschuk GD, Abel ED, Brunengraber H, Darley-Usmar V, Des Rosiers C, Gerszten R, Glatz JF, Griffin JL, Gropler RJ, Holzhuetter HG, Kizer JR, Lewandowski ED, Malloy CR, Neubauer S, Peterson LR, Portman MA, Recchia FA, Van Eyk JE, Wang TJ. Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association. Circ Res. 2016 May 13; 118(10):1659-701. PMID: 27012580.
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    34. Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016; 12(1):1-222. PMID: 26799652.
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    35. Hamirani YS, Kundu BK, Zhong M, McBride A, Li Y, Davogustto GE, Taegtmeyer H, Bourque JM. Noninvasive Detection of Early Metabolic Left Ventricular Remodeling in Systemic Hypertension. Cardiology. 2016; 133(3):157-62. PMID: 26594908.
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    36. Harmancey R, Haight DL, Watts KA, Taegtmeyer H. Chronic Hyperinsulinemia Causes Selective Insulin Resistance and Down-regulates Uncoupling Protein 3 (UCP3) through the Activation of Sterol Regulatory Element-binding Protein (SREBP)-1 Transcription Factor in the Mouse Heart. J Biol Chem. 2015 Dec 25; 290(52):30947-61. PMID: 26555260.
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    37. Taegtmeyer H, Beauloye C, Harmancey R, Hue L. Comment on Nolan et al. Insulin Resistance as a Physiological Defense Against Metabolic Stress: Implications for the Management of Subsets of Type 2 Diabetes. Diabetes 2015;64:673-686. Diabetes. 2015 Oct; 64(10):e37. PMID: 26405279.
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    38. Wu SP, Kao CY, Wang L, Creighton CJ, Yang J, Donti TR, Harmancey R, Vasquez HG, Graham BH, Bellen HJ, Taegtmeyer H, Chang CP, Tsai MJ, Tsai SY. Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure. Nat Commun. 2015 Sep 10; 6:8245. PMID: 26356605.
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    39. Davogustto G, Taegtmeyer H. Perhexiline, Cardiac Energetics, and Heart Failure: Lessons From the First Law of Thermodynamics. JACC Heart Fail. 2015 Aug; 3(8):659-60. PMID: 26251097.
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    40. Riggs K, Ali H, Taegtmeyer H, Gutierrez AD. The Use of SGLT-2 Inhibitors in Type 2 Diabetes and Heart Failure. Metab Syndr Relat Disord. 2015 Sep; 13(7):292-7. PMID: 26125313.
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    41. Davogustto G, Taegtmeyer H. The changing landscape of cardiac metabolism. J Mol Cell Cardiol. 2015 Jul; 84:129-32. PMID: 25937535.
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    42. Kundu BK, Zhong M, Sen S, Davogustto G, Keller SR, Taegtmeyer H. Remodeling of glucose metabolism precedes pressure overload-induced left ventricular hypertrophy: review of a hypothesis. Cardiology. 2015; 130(4):211-20. PMID: 25791172.
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    43. Ren J, Taegtmeyer H. Too much or not enough of a good thing--The Janus faces of autophagy in cardiac fuel and protein homeostasis. J Mol Cell Cardiol. 2015 Jul; 84:223-6. PMID: 25771142.
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    44. Rees ML, Subramaniam J, Li Y, Hamilton DJ, Frazier OH, Taegtmeyer H. A PKM2 signature in the failing heart. Biochem Biophys Res Commun. 2015 Apr 10; 459(3):430-6. PMID: 25735978.
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    45. Kamel PI, Qu X, Geiszler AM, Nagrath D, Harmancey R, Taegtmeyer H, Grande-Allen KJ. Metabolic regulation of collagen gel contraction by porcine aortic valvular interstitial cells. J R Soc Interface. 2014 Dec 06; 11(101):20140852. PMID: 25320066.
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    46. Imamura M, Chang BH, Kohjima M, Li M, Hwang B, Taegtmeyer H, Harris RA, Chan L. MondoA deficiency enhances sprint performance in mice. Biochem J. 2014 Nov 15; 464(1):35-48. PMID: 25145386.
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    47. Taegtmeyer H, Lubrano G. Rethinking cardiac metabolism: metabolic cycles to refuel and rebuild the failing heart. F1000Prime Rep. 2014; 6:90. PMID: 25374668.
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    48. Drews O, Taegtmeyer H. Targeting the ubiquitin-proteasome system in heart disease: the basis for new therapeutic strategies. Antioxid Redox Signal. 2014 Dec 10; 21(17):2322-43. PMID: 25133688.
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    49. Frazier OH, Baldwin AC, Demirozu ZT, Segura AM, Hernandez R, Taegtmeyer H, Mallidi H, Cohn WE. Ventricular reconditioning and pump explantation in patients supported by continuous-flow left ventricular assist devices. J Heart Lung Transplant. 2015 Jun; 34(6):766-72. PMID: 25447571.
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    50. Despa S, Sharma S, Harris TR, Dong H, Li N, Chiamvimonvat N, Taegtmeyer H, Margulies KB, Hammock BD, Despa F. Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. J Am Heart Assoc. 2014 Aug 21; 3(4). PMID: 25146704.
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    51. Segura AM, Dris L, Massin EK, Clubb FJ, Buja LM, Frazier OH, Taegtmeyer H. Heart failure in remission for more than 13 years after removal of a left ventricular assist device. Tex Heart Inst J. 2014 Aug; 41(4):389-94. PMID: 25120391.
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    52. Gupte AA, Hamilton DJ, Cordero-Reyes AM, Youker KA, Yin Z, Estep JD, Stevens RD, Wenner B, Ilkayeva O, Loebe M, Peterson LE, Lyon CJ, Wong ST, Newgard CB, Torre-Amione G, Taegtmeyer H, Hsueh WA. Mechanical unloading promotes myocardial energy recovery in human heart failure. Circ Cardiovasc Genet. 2014 Jun; 7(3):266-76. PMID: 24825877.
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    53. Reineke EL, Benham A, Soibam B, Stashi E, Taegtmeyer H, Entman ML, Schwartz RJ, O'Malley BW. Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function. J Biol Chem. 2014 Jun 20; 289(25):17721-31. PMID: 24811170.
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    54. Kwartler CS, Chen J, Thakur D, Li S, Baskin K, Wang S, Wang ZV, Walker L, Hill JA, Epstein HF, Taegtmeyer H, Milewicz DM. Overexpression of smooth muscle myosin heavy chain leads to activation of the unfolded protein response and autophagic turnover of thick filament-associated proteins in vascular smooth muscle cells. J Biol Chem. 2014 May 16; 289(20):14075-88. PMID: 24711452.
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    55. Taegtmeyer H, Lam T. In the footsteps of Virchow. JACC Cardiovasc Imaging. 2014 Apr; 7(4):432-3. PMID: 24742896.
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    56. Baskin KK, Rodriguez MR, Kansara S, Chen W, Carranza S, Frazier OH, Glass DJ, Taegtmeyer H. MAFbx/Atrogin-1 is required for atrophic remodeling of the unloaded heart. J Mol Cell Cardiol. 2014 Jul; 72:168-76. PMID: 24650875.
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    57. Carley AN, Taegtmeyer H, Lewandowski ED. Matrix revisited: mechanisms linking energy substrate metabolism to the function of the heart. Circ Res. 2014 Feb 14; 114(4):717-29. PMID: 24526677.
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    58. Cordero-Reyes AM, Gupte AA, Youker KA, Loebe M, Hsueh WA, Torre-Amione G, Taegtmeyer H, Hamilton DJ. Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function. J Mol Cell Cardiol. 2014 Mar; 68:98-105. PMID: 24412531.
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    59. Ekeruo IA, Solhpour A, Taegtmeyer H. Metformin in Diabetic Patients with Heart Failure: Safe and Effective? Curr Cardiovasc Risk Rep. 2013 Dec 01; 7(6):417-422. PMID: 24466358.
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    60. Taegtmeyer H. Mixed messages. JACC Heart Fail. 2013 Dec; 1(6):548. PMID: 24622008.
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    61. Taegtmeyer H, Beauloye C, Harmancey R, Hue L. Insulin resistance protects the heart from fuel overload in dysregulated metabolic states. Am J Physiol Heart Circ Physiol. 2013 Dec; 305(12):H1693-7. PMID: 24097426.
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    62. Harmancey R, Vasquez HG, Guthrie PH, Taegtmeyer H. Decreased long-chain fatty acid oxidation impairs postischemic recovery of the insulin-resistant rat heart. FASEB J. 2013 Oct; 27(10):3966-78. PMID: 23825227.
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    63. Chintalgattu V, Rees ML, Culver JC, Goel A, Jiffar T, Zhang J, Dunner K, Pati S, Bankson JA, Pasqualini R, Arap W, Bryan NS, Taegtmeyer H, Langley RR, Yao H, Kupferman ME, Entman ML, Dickinson ME, Khakoo AY. Coronary microvascular pericytes are the cellular target of sunitinib malate-induced cardiotoxicity. Sci Transl Med. 2013 May 29; 5(187):187ra69. PMID: 23720580.
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    64. Sen S, Kundu BK, Wu HC, Hashmi SS, Guthrie P, Locke LW, Roy RJ, Matherne GP, Berr SS, Terwelp M, Scott B, Carranza S, Frazier OH, Glover DK, Dillmann WH, Gambello MJ, Entman ML, Taegtmeyer H. Glucose regulation of load-induced mTOR signaling and ER stress in mammalian heart. J Am Heart Assoc. 2013 May 17; 2(3):e004796. PMID: 23686371.
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    65. Taegtmeyer H. Refugee cardiologists and the coexistence of the American Heart Association and the American College of Cardiology. J Am Coll Cardiol. 2013 Aug 13; 62(7):645-6. PMID: 23643504.
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    66. Desmoulin F, Galinier M, Trouillet C, Berry M, Delmas C, Turkieh A, Massabuau P, Taegtmeyer H, Smih F, Rouet P. Metabonomics analysis of plasma reveals the lactate to cholesterol ratio as an independent prognostic factor of short-term mortality in acute heart failure. PLoS One. 2013; 8(4):e60737. PMID: 23573279.
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    67. Khalaf KI, Taegtmeyer H. Clues from bariatric surgery: reversing insulin resistance to heal the heart. Curr Diab Rep. 2013 Apr; 13(2):245-51. PMID: 23354680.
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    68. Taegtmeyer H, Ingwall JS. Creatine--a dispensable metabolite? Circ Res. 2013 Mar 15; 112(6):878-80. PMID: 23493302.
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    69. Khalaf KI, Taegtmeyer H. Slimming the heart with bariatric surgery. J Am Coll Cardiol. 2013 Mar 05; 61(9):990-1. PMID: 23449436.
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    70. Zhong M, Alonso CE, Taegtmeyer H, Kundu BK. Quantitative PET imaging detects early metabolic remodeling in a mouse model of pressure-overload left ventricular hypertrophy in vivo. J Nucl Med. 2013 Apr; 54(4):609-15. PMID: 23426760.
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    71. Reineke EL, York B, Stashi E, Chen X, Tsimelzon A, Xu J, Newgard CB, Taffet GE, Taegtmeyer H, Entman ML, O'Malley BW. SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart. PLoS One. 2012; 7(12):e53395. PMID: 23300926.
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    72. Taegtmeyer H. The new cardiac metabolism. J Mol Cell Cardiol. 2013 Feb; 55:1. PMID: 23279969.
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    73. Khalaf K, Taegtmeyer H. Weight loss surgery, left ventricular mass and repolarization. Am J Cardiol. 2012 Nov 15; 110(10):1551-2. PMID: 23102231.
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    74. Taegtmeyer H, Rodriguez A. More than just an engine: the heart regulates body weight. Circ Res. 2012 Aug 17; 111(5):513-5. PMID: 22904039.
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    75. Ananaba I, Taegtmeyer H. Low serum cholesterol as prognostic indicator in heart failure. J Card Fail. 2012 Jul; 18(7):596. PMID: 22748494.
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    76. Harmancey R, Lam TN, Lubrano GM, Guthrie PH, Vela D, Taegtmeyer H. Insulin resistance improves metabolic and contractile efficiency in stressed rat heart. FASEB J. 2012 Aug; 26(8):3118-26. PMID: 22611083.
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    77. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490.
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    78. Algahim MF, Sen S, Taegtmeyer H. Bariatric surgery to unload the stressed heart: a metabolic hypothesis. Am J Physiol Heart Circ Physiol. 2012 Apr 15; 302(8):H1539-45. PMID: 22307676.
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    79. Osterholt M, Sen S, Dilsizian V, Taegtmeyer H. Targeted metabolic imaging to improve the management of heart disease. JACC Cardiovasc Imaging. 2012 Feb; 5(2):214-26. PMID: 22340831.
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    80. Despa S, Margulies KB, Chen L, Knowlton AA, Havel PJ, Taegtmeyer H, Bers DM, Despa F. Hyperamylinemia contributes to cardiac dysfunction in obesity and diabetes: a study in humans and rats. Circ Res. 2012 Feb 17; 110(4):598-608. PMID: 22275486.
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    81. Khalaf KI, Taegtmeyer H. After avandia: the use of antidiabetic drugs in patients with heart failure. Tex Heart Inst J. 2012; 39(2):174-8. PMID: 22740727.
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    82. Kaynak HE, Taegtmeyer H. Is bitter better? The benefits of chocolate for the cardiovascular system. Curr Hypertens Rep. 2011 Dec; 13(6):401-3. PMID: 21953488.
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    83. Ramani R, Vela D, Segura A, McNamara D, Lemster B, Samarendra V, Kormos R, Toyoda Y, Bermudez C, Frazier OH, Moravec CS, Gorcsan J, Taegtmeyer H, McTiernan CF. A micro-ribonucleic acid signature associated with recovery from assist device support in 2 groups of patients with severe heart failure. J Am Coll Cardiol. 2011 Nov 22; 58(22):2270-8. PMID: 22093502.
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    84. Taegtmeyer H, Khalaf KI. Letter by Taegtmeyer and Khalaf regarding article, "Glucose-insulin-potassium reduces the incidence of low cardiac output episodes after aortic valve replacement for aortic stenosis in patients with left ventricular hypertrophy: results from the hypertrophy, insulin, glucose, and electrolytes (HINGE) trial". Circulation. 2011 Oct 04; 124(14):e385; author reply e386. PMID: 21969324.
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    85. Baskin KK, Taegtmeyer H. AMP-activated protein kinase regulates E3 ligases in rodent heart. Circ Res. 2011 Oct 28; 109(10):1153-61. PMID: 21921267.
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    86. Taegtmeyer H. Metabolic crosstalk in heart failure new roles for B-type natriuretic peptide. J Am Coll Cardiol. 2011 Sep 06; 58(11):1126-7. PMID: 21884949.
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    87. Baskin KK, Taegtmeyer H. An expanded role for AMP-activated protein kinase: regulator of myocardial protein degradation. Trends Cardiovasc Med. 2011 May; 21(4):124-7. PMID: 22681968.
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    88. Baskin KK, Taegtmeyer H. Taking pressure off the heart: the ins and outs of atrophic remodelling. Cardiovasc Res. 2011 May 01; 90(2):243-50. PMID: 21354996.
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    89. Ellis JM, Mentock SM, Depetrillo MA, Koves TR, Sen S, Watkins SM, Muoio DM, Cline GW, Taegtmeyer H, Shulman GI, Willis MS, Coleman RA. Mouse cardiac acyl coenzyme a synthetase 1 deficiency impairs Fatty Acid oxidation and induces cardiac hypertrophy. Mol Cell Biol. 2011 Mar; 31(6):1252-62. PMID: 21245374.
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    90. Taegtmeyer H. Richard Bing remembered. Tex Heart Inst J. 2011; 38(1):5-8. PMID: 21423462.
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    91. Khalaf KI, Taegtmeyer H. Insulin sensitizers and heart failure: an engine flooded with fuel. Curr Hypertens Rep. 2010 Dec; 12(6):399-401. PMID: 20963518.
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    92. Trakhtenbroit M, Taegtmeyer H. Adiponectin, gut hormones, and insulin resistance. Obes Surg. 2010 Dec; 20(12):1748; author reply 1749. PMID: 20838917.
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    93. Taegtmeyer H, Stanley WC. Too much or not enough of a good thing? Cardiac glucolipotoxicity versus lipoprotection. J Mol Cell Cardiol. 2011 Jan; 50(1):2-5. PMID: 20869969.
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    94. Ballal K, Wilson CR, Harmancey R, Taegtmeyer H. Obesogenic high fat western diet induces oxidative stress and apoptosis in rat heart. Mol Cell Biochem. 2010 Nov; 344(1-2):221-30. PMID: 20676734.
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    95. Thomas SY, Harmancey R, Taegtmeyer H. Fat around the heart. JACC Cardiovasc Imaging. 2010 Jul; 3(7):786-7; author reply 787. PMID: 20633860.
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    96. Algahim MF, Lux TR, Leichman JG, Boyer AF, Miller CC, Laing ST, Wilson EB, Scarborough T, Yu S, Snyder B, Wolin-Riklin C, Kyle UG, Taegtmeyer H. Progressive regression of left ventricular hypertrophy two years after bariatric surgery. Am J Med. 2010 Jun; 123(6):549-55. PMID: 20569762.
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    97. Taegtmeyer H, Leichman JG, Reyes M, Lux TR. Early benefits from weight-loss surgery. J Am Coll Cardiol. 2010 Apr 20; 55(16):1754; author reply 1754. PMID: 20394883.
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    98. Taegtmeyer H. Tracing cardiac metabolism in vivo: one substrate at a time. J Nucl Med. 2010 May 01; 51 Suppl 1:80S-87S. PMID: 20395343.
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    99. Li MV, Chen W, Harmancey RN, Nuotio-Antar AM, Imamura M, Saha P, Taegtmeyer H, Chan L. Glucose-6-phosphate mediates activation of the carbohydrate responsive binding protein (ChREBP). Biochem Biophys Res Commun. 2010 May 07; 395(3):395-400. PMID: 20382127.
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    100. Taegtmeyer H, Sen S, Vela D. Return to the fetal gene program: a suggested metabolic link to gene expression in the heart. Ann N Y Acad Sci. 2010 Feb; 1188:191-8. PMID: 20201903.
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    101. Burgmaier M, Sen S, Philip F, Wilson CR, Miller CC, Young ME, Taegtmeyer H. Metabolic adaptation follows contractile dysfunction in the heart of obese Zucker rats fed a high-fat "Western" diet. Obesity (Silver Spring). 2010 Oct; 18(10):1895-901. PMID: 20111021.
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    102. Harmancey R, Wilson CR, Wright NR, Taegtmeyer H. Western diet changes cardiac acyl-CoA composition in obese rats: a potential role for hepatic lipogenesis. J Lipid Res. 2010 Jun; 51(6):1380-93. PMID: 20093477.
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    103. Wellnitz K, Taegtmeyer H. Mechanical unloading of the failing heart exposes the dynamic nature of autophagy. Autophagy. 2010 Jan; 6(1):155-6. PMID: 19949312.
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    104. Taegtmeyer H. Helen Taussig. Tex Heart Inst J. 2010; 37(2):254. PMID: 20401311.
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    105. Samudio I, Harmancey R, Fiegl M, Kantarjian H, Konopleva M, Korchin B, Kaluarachchi K, Bornmann W, Duvvuri S, Taegtmeyer H, Andreeff M. Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction. J Clin Invest. 2010 Jan; 120(1):142-56. PMID: 20038799.
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    106. Lux TR, Taegtmeyer H. All things considered-including glucose control in the ICU. Curr Hypertens Rep. 2009 Dec; 11(6):383-4. PMID: 19895748.
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    107. Soukoulis V, Dihu JB, Sole M, Anker SD, Cleland J, Fonarow GC, Metra M, Pasini E, Strzelczyk T, Taegtmeyer H, Gheorghiade M. Micronutrient deficiencies an unmet need in heart failure. J Am Coll Cardiol. 2009 Oct 27; 54(18):1660-73. PMID: 19850206.
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    108. Kassiotis C, Ballal K, Wellnitz K, Vela D, Gong M, Salazar R, Frazier OH, Taegtmeyer H. Markers of autophagy are downregulated in failing human heart after mechanical unloading. Circulation. 2009 Sep 15; 120(11 Suppl):S191-7. PMID: 19752367.
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    109. Taegtmeyer H. Richard Bing at 100: reflections on a lion in winter. J Mol Cell Cardiol. 2009 Nov; 47(5):562-4. PMID: 19695256.
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    110. Hue L, Taegtmeyer H. The Randle cycle revisited: a new head for an old hat. Am J Physiol Endocrinol Metab. 2009 Sep; 297(3):E578-91. PMID: 19531645.
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    111. Trakhtenbroit MA, Leichman JG, Algahim MF, Miller CC, Moody FG, Lux TR, Taegtmeyer H. Body weight, insulin resistance, and serum adipokine levels 2 years after 2 types of bariatric surgery. Am J Med. 2009 May; 122(5):435-42. PMID: 19375553.
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    112. Ashrith G, Algahim MF, Taegtmeyer H. Insulin resistance: marker or mediator? Am J Med. 2009 Mar; 122(3):e13; author reply e15. PMID: 19272470.
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    113. Pound KM, Sorokina N, Ballal K, Berkich DA, Fasano M, Lanoue KF, Taegtmeyer H, O'Donnell JM, Lewandowski ED. Substrate-enzyme competition attenuates upregulated anaplerotic flux through malic enzyme in hypertrophied rat heart and restores triacylglyceride content: attenuating upregulated anaplerosis in hypertrophy. Circ Res. 2009 Mar 27; 104(6):805-12. PMID: 19213957.
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    114. Lazar HL, McDonnell M, Chipkin SR, Furnary AP, Engelman RM, Sadhu AR, Bridges CR, Haan CK, Svedjeholm R, Taegtmeyer H, Shemin RJ. The Society of Thoracic Surgeons practice guideline series: Blood glucose management during adult cardiac surgery. Ann Thorac Surg. 2009 Feb; 87(2):663-9. PMID: 19161815.
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    115. Lux TR, Taegtmeyer H. Aliskiren combined with losartan: Thor's hammer or Sigurd's sword? Curr Hypertens Rep. 2008 Dec; 10(6):432-3. PMID: 18959827.
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    116. Leichman JG, Wilson EB, Scarborough T, Aguilar D, Miller CC, Yu S, Algahim MF, Reyes M, Moody FG, Taegtmeyer H. Dramatic reversal of derangements in muscle metabolism and left ventricular function after bariatric surgery. Am J Med. 2008 Nov; 121(11):966-73. PMID: 18954843.
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    117. Thakker GD, Frangogiannis NG, Zymek PT, Sharma S, Raya JL, Barger PM, Taegtmeyer H, Entman ML, Ballantyne CM. Increased myocardial susceptibility to repetitive ischemia with high-fat diet-induced obesity. Obesity (Silver Spring). 2008 Dec; 16(12):2593-600. PMID: 18833212.
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    118. Taegtmeyer H. Have your cake and eat it? Insulin strengthens the stunned heart. Crit Care Med. 2008 Oct; 36(10):2933-4. PMID: 18812796.
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    119. Taegtmeyer H, Harmancey R. Virchow's metamorphosis revealed triglycerides in the heart. J Am Coll Cardiol. 2008 Sep 16; 52(12):1013-4. PMID: 18786483.
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    120. Taegtmeyer H, Dilsizian V. Imaging myocardial metabolism and ischemic memory. Nat Clin Pract Cardiovasc Med. 2008 Aug; 5 Suppl 2:S42-8. PMID: 18641606.
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    121. Taegtmeyer H, Algahim MF. Obesity and cardiac metabolism in women. JACC Cardiovasc Imaging. 2008 Jul; 1(4):434-5. PMID: 19356463.
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    122. Kassiotis C, Rajabi M, Taegtmeyer H. Metabolic reserve of the heart: the forgotten link between contraction and coronary flow. Prog Cardiovasc Dis. 2008 Jul-Aug; 51(1):74-88. PMID: 18634919.
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    123. Harmancey R, Wilson CR, Taegtmeyer H. Adaptation and maladaptation of the heart in obesity. Hypertension. 2008 Aug; 52(2):181-7. PMID: 18574077.
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    124. Taegtmeyer H, Harinstein ME, Gheorghiade M. More than bricks and mortar: comments on protein and amino acid metabolism in the heart. Am J Cardiol. 2008 Jun 02; 101(11A):3E-7E. PMID: 18514624.
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    125. Pasini E, Aquilani R, Dioguardi FS, D'Antona G, Gheorghiade M, Taegtmeyer H. Hypercatabolic syndrome: molecular basis and effects of nutritional supplements with amino acids. Am J Cardiol. 2008 Jun 02; 101(11A):11E-15E. PMID: 18514619.
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    126. Harmancey R, Taegtmeyer H. The complexities of diabetic cardiomyopathy: lessons from patients and animal models. Curr Diab Rep. 2008 Jun; 8(3):243-8. PMID: 18625124.
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    127. Essop MF, Camp HS, Choi CS, Sharma S, Fryer RM, Reinhart GA, Guthrie PH, Bentebibel A, Gu Z, Shulman GI, Taegtmeyer H, Wakil SJ, Abu-Elheiga L. Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice. Am J Physiol Heart Circ Physiol. 2008 Jul; 295(1):H256-65. PMID: 18487439.
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    128. Harinstein ME, Berliner JI, Shah SJ, Taegtmeyer H, Gheorghiade M. Normalization of ejection fraction and resolution of symptoms in chronic severe heart failure is possible with modern medical therapy: clinical observations in 11 patients. Am J Ther. 2008 May-Jun; 15(3):206-13. PMID: 18496257.
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    129. Guha A, Harmancey R, Taegtmeyer H. Nonischemic heart failure in diabetes mellitus. Curr Opin Cardiol. 2008 May; 23(3):241-8. PMID: 18382213.
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    130. Rajabi M, Kassiotis C, Razeghi P, Taegtmeyer H. Return to the fetal gene program protects the stressed heart: a strong hypothesis. Heart Fail Rev. 2007 Dec; 12(3-4):331-43. PMID: 17516164.
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    131. Lux TR, Taegtmeyer H. Battling the four horsemen of the metabolic syndrome. Curr Hypertens Rep. 2007 Dec; 9(6):445-6. PMID: 18367005.
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    132. Young ME, Yan J, Razeghi P, Cooksey RC, Guthrie PH, Stepkowski SM, McClain DA, Tian R, Taegtmeyer H. Proposed regulation of gene expression by glucose in rodent heart. Gene Regul Syst Bio. 2007 Nov 05; 1:251-62. PMID: 19936093.
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    133. Essop MF, Chan WY, Taegtmeyer H. Metabolic gene switching in the murine female heart parallels enhanced mitochondrial respiratory function in response to oxidative stress. FEBS J. 2007 Oct; 274(20):5278-84. PMID: 17892491.
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    134. Wilson CR, Tran MK, Salazar KL, Young ME, Taegtmeyer H. Western diet, but not high fat diet, causes derangements of fatty acid metabolism and contractile dysfunction in the heart of Wistar rats. Biochem J. 2007 Sep 15; 406(3):457-67. PMID: 17550347.
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    135. Taegtmeyer H. The failing heart. N Engl J Med. 2007 Jun 14; 356(24):2545-6; author reply 2546. PMID: 17575596.
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    136. Sharma S, Guthrie PH, Chan SS, Haq S, Taegtmeyer H. Glucose phosphorylation is required for insulin-dependent mTOR signalling in the heart. Cardiovasc Res. 2007 Oct 01; 76(1):71-80. PMID: 17553476.
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    137. Sorokina N, O'Donnell JM, McKinney RD, Pound KM, Woldegiorgis G, LaNoue KF, Ballal K, Taegtmeyer H, Buttrick PM, Lewandowski ED. Recruitment of compensatory pathways to sustain oxidative flux with reduced carnitine palmitoyltransferase I activity characterizes inefficiency in energy metabolism in hypertrophied hearts. Circulation. 2007 Apr 17; 115(15):2033-41. PMID: 17404155.
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    138. Sano M, Izumi Y, Helenius K, Asakura M, Rossi DJ, Xie M, Taffet G, Hu L, Pautler RG, Wilson CR, Boudina S, Abel ED, Taegtmeyer H, Scaglia F, Graham BH, Kralli A, Shimizu N, Tanaka H, Mäkelä TP, Schneider MD. Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1. Cell Metab. 2007 Feb; 5(2):129-42. PMID: 17276355.
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    139. Razeghi P, Wang ME, Youker KA, Golfman L, Stepkowski S, Taegtmeyer H. Lack of NF-kappaB1 (p105/p50) attenuates unloading-induced downregulation of PPARalpha and PPARalpha-regulated gene expression in rodent heart. Cardiovasc Res. 2007 Apr 01; 74(1):133-9. PMID: 17276423.
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    140. Leichman JG, Taegtmeyer H. The fat ones fare well--but is it fair to compare? Crit Care Med. 2006 Dec; 34(12):3042-3. PMID: 17130699.
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    141. Taegtmeyer H, Lux TR. Rimonabant--a new weapon in the war on obesity. Curr Hypertens Rep. 2006 Dec; 8(6):441-2. PMID: 17087852.
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    142. Taegtmeyer H, Ballal K. No low-fat diet for the failing heart? Circulation. 2006 Nov 14; 114(20):2092-3. PMID: 17101867.
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    143. Leichman JG, Aguilar D, King TM, Mehta S, Majka C, Scarborough T, Wilson EB, Taegtmeyer H. Improvements in systemic metabolism, anthropometrics, and left ventricular geometry 3 months after bariatric surgery. Surg Obes Relat Dis. 2006 Nov-Dec; 2(6):592-9. PMID: 17138229.
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    144. Razeghi P, Volpini KC, Wang ME, Youker KA, Stepkowski S, Taegtmeyer H. Mechanical unloading of the heart activates the calpain system. J Mol Cell Cardiol. 2007 Feb; 42(2):449-52. PMID: 17027024.
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    145. Razeghi P, Taegtmeyer H. Hypertrophy and atrophy of the heart: the other side of remodeling. Ann N Y Acad Sci. 2006 Oct; 1080:110-9. PMID: 17132779.
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    146. Leichman JG, Aguilar D, King TM, Vlada A, Reyes M, Taegtmeyer H. Association of plasma free fatty acids and left ventricular diastolic function in patients with clinically severe obesity. Am J Clin Nutr. 2006 Aug; 84(2):336-41. PMID: 16895880.
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    147. Razeghi P, Buksinska-Lisik M, Palanichamy N, Stepkowski S, Frazier OH, Taegtmeyer H. Transcriptional regulators of ribosomal biogenesis are increased in the unloaded heart. FASEB J. 2006 Jun; 20(8):1090-6. PMID: 16770008.
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    148. Sharma S, Dewald O, Adrogue J, Salazar RL, Razeghi P, Crapo JD, Bowler RP, Entman ML, Taegtmeyer H. Induction of antioxidant gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species. Free Radic Biol Med. 2006 Jun 15; 40(12):2223-31. PMID: 16785036.
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    149. Taegtmeyer H. Did the fat lady sing? Crit Care Med. 2006 Mar; 34(3):915-6. PMID: 16505684.
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    150. Razeghi P, Baskin KK, Sharma S, Young ME, Stepkowski S, Essop MF, Taegtmeyer H. Atrophy, hypertrophy, and hypoxemia induce transcriptional regulators of the ubiquitin proteasome system in the rat heart. Biochem Biophys Res Commun. 2006 Apr 07; 342(2):361-4. PMID: 16483544.
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    151. Sharma S, Ying J, Razeghi P, Stepkowski S, Taegtmeyer H. Atrophic remodeling of the transplanted rat heart. Cardiology. 2006; 105(2):128-36. PMID: 16391472.
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    152. Koomen JM, Wilson CR, Guthrie P, Androlewicz MJ, Kobayashi R, Taegtmeyer H. Proteome analysis of isolated perfused organ effluent as a novel model for protein biomarker discovery. J Proteome Res. 2006 Jan; 5(1):177-82. PMID: 16396509.
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    153. Razeghi P, Taegtmeyer H. Cardiac remodeling: UPS lost in transit. Circ Res. 2005 Nov 11; 97(10):964-6. PMID: 16284188.
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    154. Adrogue JV, Sharma S, Ngumbela K, Essop MF, Taegtmeyer H. Acclimatization to chronic hypobaric hypoxia is associated with a differential transcriptional profile between the right and left ventricle. Mol Cell Biochem. 2005 Oct; 278(1-2):71-8. PMID: 16180091.
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    155. McClure TD, Young ME, Taegtmeyer H, Ning XH, Buroker NE, López-Guisa J, Portman MA. Thyroid hormone interacts with PPARalpha and PGC-1 during mitochondrial maturation in sheep heart. Am J Physiol Heart Circ Physiol. 2005 Nov; 289(5):H2258-64. PMID: 16024569.
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    156. Dewald O, Sharma S, Adrogue J, Salazar R, Duerr GD, Crapo JD, Entman ML, Taegtmeyer H. Downregulation of peroxisome proliferator-activated receptor-alpha gene expression in a mouse model of ischemic cardiomyopathy is dependent on reactive oxygen species and prevents lipotoxicity. Circulation. 2005 Jul 19; 112(3):407-15. PMID: 16009788.
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    157. Taegtmeyer H. Glucose for the heart: too much of a good thing? J Am Coll Cardiol. 2005 Jul 05; 46(1):49-50. PMID: 15992634.
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    158. Taegtmeyer H, Wilson CR, Razeghi P, Sharma S. Metabolic energetics and genetics in the heart. Ann N Y Acad Sci. 2005 Jun; 1047:208-18. PMID: 16093498.
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    159. Golfman LS, Wilson CR, Sharma S, Burgmaier M, Young ME, Guthrie PH, Van Arsdall M, Adrogue JV, Brown KK, Taegtmeyer H. Activation of PPARgamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats. Am J Physiol Endocrinol Metab. 2005 Aug; 289(2):E328-36. PMID: 15797988.
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    160. Skurk C, Izumiya Y, Maatz H, Razeghi P, Shiojima I, Sandri M, Sato K, Zeng L, Schiekofer S, Pimentel D, Lecker S, Taegtmeyer H, Goldberg AL, Walsh K. The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling. J Biol Chem. 2005 May 27; 280(21):20814-23. PMID: 15781459.
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    161. Taegtmeyer H, Salazar R. Myocardial metabolism: a new target for the treatment of heart disease? Curr Hypertens Rep. 2004 Dec; 6(6):414-5. PMID: 15527683.
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    162. Sharma S, Adrogue JV, Golfman L, Uray I, Lemm J, Youker K, Noon GP, Frazier OH, Taegtmeyer H. Intramyocardial lipid accumulation in the failing human heart resembles the lipotoxic rat heart. FASEB J. 2004 Nov; 18(14):1692-700. PMID: 15522914.
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    163. Nemoto S, Razeghi P, Ishiyama M, De Freitas G, Taegtmeyer H, Carabello BA. PPAR-gamma agonist rosiglitazone ameliorates ventricular dysfunction in experimental chronic mitral regurgitation. Am J Physiol Heart Circ Physiol. 2005 Jan; 288(1):H77-82. PMID: 15345480.
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    164. Taegtmeyer H. Cardiac metabolism as a target for the treatment of heart failure. Circulation. 2004 Aug 24; 110(8):894-6. PMID: 15326079.
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    165. Taegtmeyer H. Glycogen in the heart--an expanded view. J Mol Cell Cardiol. 2004 Jul; 37(1):7-10. PMID: 15242730.
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    166. Erol E, Cline GW, Kim JK, Taegtmeyer H, Binas B. Nonacute effects of H-FABP deficiency on skeletal muscle glucose uptake in vitro. Am J Physiol Endocrinol Metab. 2004 Nov; 287(5):E977-82. PMID: 15198933.
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    167. Taegtmeyer H, Golfman L, Sharma S, Razeghi P, van Arsdall M. Linking gene expression to function: metabolic flexibility in the normal and diseased heart. Ann N Y Acad Sci. 2004 May; 1015:202-13. PMID: 15201161.
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    168. Woods AA, Taegtmeyer H. Reversal of glucose-insulin-potassium-induced hyperglycemia by aggressive insulin treatment in postoperative heart failure. An observational study. Cardiology. 2004; 102(2):82-8. PMID: 15103177.
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    169. Gould KL, Taegtmeyer H. Myocardial ischemia, fluorodeoxyglucose, and severity of coronary artery stenosis: the complexities of metabolic remodeling in hibernating myocardium. Circulation. 2004 Mar 30; 109(12):e167-70; author reply e167-70. PMID: 15051653.
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    170. Essop MF, Razeghi P, McLeod C, Young ME, Taegtmeyer H, Sack MN. Hypoxia-induced decrease of UCP3 gene expression in rat heart parallels metabolic gene switching but fails to affect mitochondrial respiratory coupling. Biochem Biophys Res Commun. 2004 Feb 06; 314(2):561-4. PMID: 14733944.
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    171. Taegtmeyer H, Razeghi P. Heart disease in diabetes--resist the beginnings. J Am Coll Cardiol. 2004 Jan 21; 43(2):315; author reply 315. PMID: 14736456.
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    172. Razeghi P, Taegtmeyer H. Activity of the Akt/GSK-3beta pathway in the failing human heart before and after left ventricular assist device support. Cardiovasc Res. 2004 Jan 01; 61(1):196-7; author reply 198-9. PMID: 14732217.
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    173. Bruckner BA, Razeghi P, Stetson S, Thompson L, Lafuente J, Entman M, Loebe M, Noon G, Taegtmeyer H, Frazier OH, Youker K. Degree of cardiac fibrosis and hypertrophy at time of implantation predicts myocardial improvement during left ventricular assist device support. J Heart Lung Transplant. 2004 Jan; 23(1):36-42. PMID: 14734125.
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    174. Weisleder N, Soumaka E, Abbasi S, Taegtmeyer H, Capetanaki Y. Cardiomyocyte-specific desmin rescue of desmin null cardiomyopathy excludes vascular involvement. J Mol Cell Cardiol. 2004 Jan; 36(1):121-8. PMID: 14734054.
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    175. Taegtmeyer H, Sharma S. Anemia and energy depletion. J Am Coll Cardiol. 2003 Dec 03; 42(11):2030; author reply 2030. PMID: 14662270.
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    176. Taegtmeyer H, Woods A. Clinical trials report. Metabolic modulation as a principle for myocardial protection. Curr Hypertens Rep. 2003 Dec; 5(6):443-4. PMID: 14594561.
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    177. Sharma S, Taegtmeyer H, Adrogue J, Razeghi P, Sen S, Ngumbela K, Essop MF. Dynamic changes of gene expression in hypoxia-induced right ventricular hypertrophy. Am J Physiol Heart Circ Physiol. 2004 Mar; 286(3):H1185-92. PMID: 14630626.
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    178. Razeghi P, Sharma S, Ying J, Li YP, Stepkowski S, Reid MB, Taegtmeyer H. Atrophic remodeling of the heart in vivo simultaneously activates pathways of protein synthesis and degradation. Circulation. 2003 Nov 18; 108(20):2536-41. PMID: 14610007.
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    179. Castro-Chavez F, Yechoor VK, Saha PK, Martinez-Botas J, Wooten EC, Sharma S, O'Connell P, Taegtmeyer H, Chan L. Coordinated upregulation of oxidative pathways and downregulation of lipid biosynthesis underlie obesity resistance in perilipin knockout mice: a microarray gene expression profile. Diabetes. 2003 Nov; 52(11):2666-74. PMID: 14578284.
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    180. Haffner S, Taegtmeyer H. Epidemic obesity and the metabolic syndrome. Circulation. 2003 Sep 30; 108(13):1541-5. PMID: 14517149.
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    181. Cohen DM, Guthrie PH, Gao X, Sakai R, Taegtmeyer H. Glutamine cycling in isolated working rat heart. Am J Physiol Endocrinol Metab. 2003 Dec; 285(6):E1312-6. PMID: 12944323.
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    182. Uray IP, Connelly JH, Frazier OH, Taegtmeyer H, Davies PJ. Mechanical unloading increases caveolin expression in the failing human heart. Cardiovasc Res. 2003 Jul 01; 59(1):57-66. PMID: 12829176.
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    183. Razeghi P, Essop MF, Huss JM, Abbasi S, Manga N, Taegtmeyer H. Hypoxia-induced switches of myosin heavy chain iso-gene expression in rat heart. Biochem Biophys Res Commun. 2003 Apr 18; 303(4):1024-7. PMID: 12684037.
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    184. Sheikh-Hamad D, Bick R, Wu GY, Christensen BM, Razeghi P, Poindexter B, Taegtmeyer H, Wamsley A, Padda R, Entman M, Nielsen S, Youker K. Stanniocalcin-1 is a naturally occurring L-channel inhibitor in cardiomyocytes: relevance to human heart failure. Am J Physiol Heart Circ Physiol. 2003 Jul; 285(1):H442-8. PMID: 12663264.
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    185. Xia Y, Wen HY, Young ME, Guthrie PH, Taegtmeyer H, Kellems RE. Mammalian target of rapamycin and protein kinase A signaling mediate the cardiac transcriptional response to glutamine. J Biol Chem. 2003 Apr 11; 278(15):13143-50. PMID: 12522136.
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    186. Taegtmeyer H. Myocardial energetics: still only the tip of an iceberg. Heart Lung Circ. 2003; 12(1):3-6. PMID: 16352098.
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    187. Sharma S, Razeghi P, Shakir A, Keneson BJ, Clubb F, Taegtmeyer H. Regional heterogeneity in gene expression profiles: a transcript analysis in human and rat heart. Cardiology. 2003; 100(2):73-9. PMID: 14557693.
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    188. Razeghi P, Bruckner BA, Sharma S, Youker KA, Frazier OH, Taegtmeyer H. Mechanical unloading of the failing human heart fails to activate the protein kinase B/Akt/glycogen synthase kinase-3beta survival pathway. Cardiology. 2003; 100(1):17-22. PMID: 12975541.
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    189. Taegtmeyer H, Wilson CR. Obesity and the risk of heart failure. N Engl J Med. 2002 Dec 05; 347(23):1887-9; author reply 1887-9. PMID: 12472068.
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    190. Taegtmeyer H, Cohen DM. Overestimating glycolysis in rat heart. Am J Physiol Endocrinol Metab. 2002 Nov; 283(5):E1102-3; author reply E1103-4. PMID: 12395804.
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    191. Taegtmeyer H. Switching metabolic genes to build a better heart. Circulation. 2002 Oct 15; 106(16):2043-5. PMID: 12379570.
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    192. Young ME, Guthrie PH, Razeghi P, Leighton B, Abbasi S, Patil S, Youker KA, Taegtmeyer H. Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart. Diabetes. 2002 Aug; 51(8):2587-95. PMID: 12145175.
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    193. Razeghi P, Young ME, Cockrill TC, Frazier OH, Taegtmeyer H. Downregulation of myocardial myocyte enhancer factor 2C and myocyte enhancer factor 2C-regulated gene expression in diabetic patients with nonischemic heart failure. Circulation. 2002 Jul 23; 106(4):407-11. PMID: 12135937.
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    194. Uray IP, Connelly JH, Thomázy V, Shipley GL, Vaughn WK, Frazier OH, Taegtmeyer H, Davies PJ. Left ventricular unloading alters receptor tyrosine kinase expression in the failing human heart. J Heart Lung Transplant. 2002 Jul; 21(7):771-82. PMID: 12100903.
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    195. Young ME, McNulty P, Taegtmeyer H. Adaptation and maladaptation of the heart in diabetes: Part II: potential mechanisms. Circulation. 2002 Apr 16; 105(15):1861-70. PMID: 11956132.
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    196. Taegtmeyer H, McNulty P, Young ME. Adaptation and maladaptation of the heart in diabetes: Part I: general concepts. Circulation. 2002 Apr 09; 105(14):1727-33. PMID: 11940554.
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    197. Taegtmeyer H, Razeghi P, Young ME. Mitochondrial proteins in hypertrophy and atrophy: a transcript analysis in rat heart. Clin Exp Pharmacol Physiol. 2002 Apr; 29(4):346-50. PMID: 11985548.
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    198. Belke DD, Betuing S, Tuttle MJ, Graveleau C, Young ME, Pham M, Zhang D, Cooksey RC, McClain DA, Litwin SE, Taegtmeyer H, Severson D, Kahn CR, Abel ED. Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression. J Clin Invest. 2002 Mar; 109(5):629-39. PMID: 11877471.
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    199. Young ME, Wilson CR, Razeghi P, Guthrie PH, Taegtmeyer H. Alterations of the circadian clock in the heart by streptozotocin-induced diabetes. J Mol Cell Cardiol. 2002 Feb; 34(2):223-31. PMID: 11851361.
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    200. Razeghi P, Young ME, Ying J, Depre C, Uray IP, Kolesar J, Shipley GL, Moravec CS, Davies PJ, Frazier OH, Taegtmeyer H. Downregulation of metabolic gene expression in failing human heart before and after mechanical unloading. Cardiology. 2002; 97(4):203-9. PMID: 12145475.
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    201. Razeghi P, Myers TJ, Frazier OH, Taegtmeyer H. Reverse remodeling of the failing human heart with mechanical unloading. Emerging concepts and unanswered questions. Cardiology. 2002; 98(4):167-74. PMID: 12566644.
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