Harikanth Venkannagari

TitlePostdoc Fellows and Associates
InstitutionBaylor College of Medicine
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Venkannagari H, Kasper JM, Misra A, Rush SA, Fan S, Lee H, Sun H, Seshadrinathan S, Machius M, Hommel JD, Rudenko G. Highly Conserved Molecular Features in IgLONs Contrast Their Distinct Structural and Biological Outcomes. J Mol Biol. 2020 09 04; 432(19):5287-5303. PMID: 32710982.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Yin Z, Venkannagari H, Lynch H, Aglyamova G, Bhandari M, Machius M, Nestler EJ, Robison AJ, Rudenko G. Self-assembly of the bZIP transcription factor ?FosB. Curr Res Struct Biol. 2020; 2:1-13. PMID: 32542236.
    3. Murthy S, Desantis J, Verheugd P, Maksimainen MM, Venkannagari H, Massari S, Ashok Y, Obaji E, Nkizinkinko Y, Lüscher B, Tabarrini O, Lehtiö L. 4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10. Eur J Med Chem. 2018 Aug 05; 156:93-102. PMID: 30006177.
      Citations: 5     Fields:    Translation:HumansCells
    4. Zhang Y, Jumppanen M, Maksimainen MM, Auno S, Awol Z, Ghemtio L, Venkannagari H, Lehtiö L, Yli-Kauhaluoma J, Xhaard H, Boije Af Gennäs G. Adenosine analogs bearing phosphate isosteres as human MDO1 ligands. Bioorg Med Chem. 2018 05 01; 26(8):1588-1597. PMID: 29501416.
      Citations: 2     Fields:    Translation:HumansCells
    5. Venkannagari H, Verheugd P, Koivunen J, Haikarainen T, Obaji E, Ashok Y, Narwal M, Pihlajaniemi T, Lüscher B, Lehtiö L. Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage. Cell Chem Biol. 2016 Oct 20; 23(10):1251-1260. PMID: 27667561.
      Citations: 10     Fields:    Translation:HumansCells
    6. Schlesinger M, Vilchez Larrea SC, Haikarainen T, Narwal M, Venkannagari H, Flawiá MM, Lehtiö L, Fernández Villamil SH. Disrupted ADP-ribose metabolism with nuclear Poly (ADP-ribose) accumulation leads to different cell death pathways in presence of hydrogen peroxide in procyclic Trypanosoma brucei. Parasit Vectors. 2016 Mar 23; 9:173. PMID: 27007296.
      Citations: 4     Fields:    Translation:Animals
    7. Haikarainen T, Waaler J, Ignatev A, Nkizinkiko Y, Venkannagari H, Obaji E, Krauss S, Lehtiö L. Development and structural analysis of adenosine site binding tankyrase inhibitors. Bioorg Med Chem Lett. 2016 Jan 15; 26(2):328-333. PMID: 26706174.
      Citations: 4     Fields:    Translation:HumansCells
    8. Nkizinkiko Y, Suneel Kumar BVS, Jeankumar VU, Haikarainen T, Koivunen J, Madhuri C, Yogeeswari P, Venkannagari H, Obaji E, Pihlajaniemi T, Sriram D, Lehtiö L. Discovery of potent and selective nonplanar tankyrase inhibiting nicotinamide mimics. Bioorg Med Chem. 2015 Aug 01; 23(15):4139-4149. PMID: 26183543.
      Citations: 5     Fields:    Translation:HumansCells
    9. Haikarainen T, Koivunen J, Narwal M, Venkannagari H, Obaji E, Joensuu P, Pihlajaniemi T, Lehtiö L. para-Substituted 2-phenyl-3,4-dihydroquinazolin-4-ones as potent and selective tankyrase inhibitors. ChemMedChem. 2013 Dec; 8(12):1978-85. PMID: 24130191.
      Citations: 7     Fields:    Translation:HumansCells
    10. Narwal M, Koivunen J, Haikarainen T, Obaji E, Legala OE, Venkannagari H, Joensuu P, Pihlajaniemi T, Lehtiö L. Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J Med Chem. 2013 Oct 24; 56(20):7880-9. PMID: 24116873.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    11. Haikarainen T, Venkannagari H, Narwal M, Obaji E, Lee HW, Nkizinkiko Y, Lehtiö L. Structural basis and selectivity of tankyrase inhibition by a Wnt signaling inhibitor WIKI4. PLoS One. 2013; 8(6):e65404. PMID: 23762361.
      Citations: 12     Fields:    Translation:HumansCells
    12. Venkannagari H, Fallarero A, Feijs KL, Lüscher B, Lehtiö L. Activity-based assay for human mono-ADP-ribosyltransferases ARTD7/PARP15 and ARTD10/PARP10 aimed at screening and profiling inhibitors. Eur J Pharm Sci. 2013 May 13; 49(2):148-56. PMID: 23485441.
      Citations: 13     Fields:    Translation:HumansCells
    13. Vilchez Larrea SC, Haikarainen T, Narwal M, Schlesinger M, Venkannagari H, Flawiá MM, Villamil SH, Lehtiö L. Inhibition of poly(ADP-ribose) polymerase interferes with Trypanosoma cruzi infection and proliferation of the parasite. PLoS One. 2012; 7(9):e46063. PMID: 23049934.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    14. Narwal M, Venkannagari H, Lehtiö L. Structural basis of selective inhibition of human tankyrases. J Med Chem. 2012 Feb 09; 55(3):1360-7. PMID: 22233320.
      Citations: 44     Fields:    Translation:HumansCells
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