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GEORGE R JACKSON

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Neurology
DivisionNeurology
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    K08NS002116     (JACKSON, GEORGE R)Jul 5, 1999 - Aug 31, 2004
    NIH/NINDS
    Molecular Genetics of Polyglutamine-Induced Degeneration
    Role: Principal Investigator

    R01NS046489     (JACKSON, GEORGE R)Jul 15, 2004 - Jun 30, 2009
    NIH/NINDS
    Molecular Genetics of Tau-Associated Neurodegeneration
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Jackson GR. Lifestyles of a Toxic Twosome: A Novel Tau Strain Induced by a-Synuclein Oligomers. Biol Psychiatry. 2018 Oct 01; 84(7):472-473. PMID: 30176989.
      View in: PubMed
    2. Jackson GR, Maione AG, Klausner M, Hayden PJ. Prevalidation of an Acute Inhalation Toxicity Test Using the EpiAirway In Vitro Human Airway Model. Appl In Vitro Toxicol. 2018 Jun 01; 4(2):149-158. PMID: 29904643.
      View in: PubMed
    3. Jackson GR. SCA31 Flies Perform in a Balancing Act between RAN Translation and RNA-Binding Proteins. Neuron. 2017 04 05; 94(1):4-5. PMID: 28384473.
      View in: PubMed
    4. Bryant MS, Workman CD, Jamal F, Meng H, Jackson GR. Feasibility study: Effect of hand resistance exercise on handwriting in Parkinson's disease and essential tremor. J Hand Ther. 2018 Jan - Mar; 31(1):29-34. PMID: 28389133.
      View in: PubMed
    5. Moses E, Wang T, Corbett S, Jackson GR, Drizik E, Perdomo C, Perdomo C, Kleerup E, Brooks D, O'Connor G, Dubinett S, Hayden P, Lenburg ME, Spira A. Molecular Impact of Electronic Cigarette Aerosol Exposure in Human Bronchial Epithelium. Toxicol Sci. 2017 01; 155(1):248-257. PMID: 27701119.
      View in: PubMed
    6. Newsome MR, Mayer AR, Lin X, Troyanskaya M, Jackson GR, Scheibel RS, Walder A, Sathiyaraj A, Wilde EA, Mukhi S, Taylor BA, Levin HS. Chronic Effects of Blast-Related TBI on Subcortical Functional Connectivity in Veterans - Erratum. J Int Neuropsychol Soc. 2016 08; 22(7):790-2. PMID: 27459379.
      View in: PubMed
    7. Chouhan AK, Guo C, Hsieh YC, Ye H, Senturk M, Zuo Z, Li Y, Chatterjee S, Botas J, Jackson GR, Bellen HJ, Shulman JM. Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease. Acta Neuropathol Commun. 2016 06 23; 4(1):62. PMID: 27338814.
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    8. Newsome MR, Mayer AR, Lin X, Troyanskaya M, Jackson GR, Scheibel RS, Walder A, Sathiyaraj A, Wilde EA, Mukhi S, Taylor BA, Levin HS. Chronic Effects of Blast-Related TBI on Subcortical Functional Connectivity in Veterans. J Int Neuropsychol Soc. 2016 07; 22(6):631-42. PMID: 27264731.
      View in: PubMed
    9. Iyer J, Wang Q, Le T, Pizzo L, Grönke S, Ambegaokar SS, Imai Y, Srivastava A, Troisí BL, Mardon G, Artero R, Jackson GR, Isaacs AM, Partridge L, Lu B, Kumar JP, Girirajan S. Quantitative Assessment of Eye Phenotypes for Functional Genetic Studies Using Drosophila melanogaster. G3 (Bethesda). 2016 05 03; 6(5):1427-37. PMID: 26994292.
      View in: PubMed
    10. Stem MS, Dunbar GE, Jackson GR, Farsiu S, Pop-Busui R, Gardner TW. Glucose variability and inner retinal sensory neuropathy in persons with type 1 diabetes mellitus. Eye (Lond). 2016 Jun; 30(6):825-32. PMID: 27034201.
      View in: PubMed
    11. Bryant MS, Jackson GR, Hou JG, Protas EJ. Treadmill exercise tests in persons with Parkinson's disease: responses and disease severity. Aging Clin Exp Res. 2016 Oct; 28(5):1009-14. PMID: 26590841.
      View in: PubMed
    12. Lever AR, Park H, Mulhern TJ, Jackson GR, Comolli JC, Borenstein JT, Hayden PJ, Prantil-Baun R. Comprehensive evaluation of poly(I:C) induced inflammatory response in an airway epithelial model. Physiol Rep. 2015 Apr; 3(4). PMID: 25847914.
      View in: PubMed
    13. Bryant MS, Workman CD, Jackson GR. Multidirectional walk test in individuals with Parkinson's disease: a validity study. Int J Rehabil Res. 2015 Mar; 38(1):88-91. PMID: 25371075.
      View in: PubMed
    14. Bai J, Smock SL, Jackson GR, MacIsaac KD, Huang Y, Mankus C, Oldach J, Roberts B, Ma YL, Klappenbach JA, Crackower MA, Alves SE, Hayden PJ. Phenotypic responses of differentiated asthmatic human airway epithelial cultures to rhinovirus. PLoS One. 2015; 10(2):e0118286. PMID: 25706956.
      View in: PubMed
    15. Sengupta U, Guerrero-Muñoz MJ, Castillo-Carranza DL, Lasagna-Reeves CA, Gerson JE, Paulucci-Holthauzen AA, Krishnamurthy S, Farhed M, Jackson GR, Kayed R. Pathological interface between oligomeric alpha-synuclein and tau in synucleinopathies. Biol Psychiatry. 2015 Nov 15; 78(10):672-83. PMID: 25676491.
      View in: PubMed
    16. Jackson GR. Learn to forget: regulation of age-related memory impairment by neuronal-glial crosstalk. Neuron. 2014 Nov 19; 84(4):658-9. PMID: 25459404.
      View in: PubMed
    17. Guerrero-Muñoz MJ, Castillo-Carranza DL, Krishnamurthy S, Paulucci-Holthauzen AA, Sengupta U, Lasagna-Reeves CA, Ahmad Y, Jackson GR, Kayed R. Amyloid-ß oligomers as a template for secondary amyloidosis in Alzheimer's disease. Neurobiol Dis. 2014 Nov; 71:14-23. PMID: 25134727.
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    18. Lasagna-Reeves CA, Sengupta U, Castillo-Carranza D, Gerson JE, Guerrero-Munoz M, Troncoso JC, Jackson GR, Kayed R. The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Acta Neuropathol Commun. 2014 May 29; 2:56. PMID: 24887264.
      View in: PubMed
    19. Yassin AM, Shroff S, Patel SD, Paker AM, Berman MA, Jackson GR. Hemichorea in a patient with diabetic ketoacidosis. J Neurol Sci. 2014 Jul 15; 342(1-2):189-91. PMID: 24857350.
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    20. Castillo-Carranza DL, Sengupta U, Guerrero-Muñoz MJ, Lasagna-Reeves CA, Gerson JE, Singh G, Estes DM, Barrett AD, Dineley KT, Jackson GR, Kayed R. Passive immunization with Tau oligomer monoclonal antibody reverses tauopathy phenotypes without affecting hyperphosphorylated neurofibrillary tangles. J Neurosci. 2014 Mar 19; 34(12):4260-72. PMID: 24647946.
      View in: PubMed
    21. Bakhoum MF, Bakhoum CY, Ding Z, Carlton SM, Campbell GA, Jackson GR. Evidence for autophagic gridlock in aging and neurodegeneration. Transl Res. 2014 Jul; 164(1):1-12. PMID: 24561013.
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    22. Roy B, Jackson GR. Interactions between Tau and a-synuclein augment neurotoxicity in a Drosophila model of Parkinson's disease. Hum Mol Genet. 2014 Jun 01; 23(11):3008-23. PMID: 24430504.
      View in: PubMed
    23. Perdomo C, Campbell JD, Gerrein J, Tellez CS, Garrison CB, Walser TC, Drizik E, Si H, Gower AC, Vick J, Anderlind C, Jackson GR, Mankus C, Schembri F, O'Hara C, Gomperts BN, Dubinett SM, Hayden P, Belinsky SA, Lenburg ME, Spira A. MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):18946-51. PMID: 24158479.
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    24. Choksi DK, Roy B, Chatterjee S, Yusuff T, Bakhoum MF, Sengupta U, Ambegaokar S, Kayed R, Jackson GR. TDP-43 Phosphorylation by casein kinase Ie promotes oligomerization and enhances toxicity in vivo. Hum Mol Genet. 2014 Feb 15; 23(4):1025-35. PMID: 24105464.
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    25. Wightman PJ, Jackson GR, Dipple KM. Disruption of glycerol metabolism by RNAi targeting of genes encoding glycerol kinase results in a range of phenotype severity in Drosophila. PLoS One. 2013; 8(9):e71664. PMID: 24039719.
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    26. Hawkins BE, Krishnamurthy S, Castillo-Carranza DL, Sengupta U, Prough DS, Jackson GR, DeWitt DS, Kayed R. Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies. J Biol Chem. 2013 Jun 07; 288(23):17042-50. PMID: 23632019.
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    27. Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Guerrero-Munoz MJ, Kiritoshi T, Neugebauer V, Jackson GR, Kayed R. Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau. Sci Rep. 2012; 2:700. PMID: 23050084.
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    28. Ambegaokar SS, Jackson GR. The downward spiral of tau and autolysosomes: a new hypothesis in neurodegeneration. Autophagy. 2012 Jul 01; 8(7):1144-5. PMID: 22635052.
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    29. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490.
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    30. Wightman PJ, Jackson GR, Dipple KM. Glycerol hypersensitivity in a Drosophila model for glycerol kinase deficiency is affected by mutations in eye pigmentation genes. PLoS One. 2012; 7(3):e31779. PMID: 22427807.
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    31. Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Sarmiento J, Troncoso J, Jackson GR, Kayed R. Identification of oligomers at early stages of tau aggregation in Alzheimer's disease. FASEB J. 2012 May; 26(5):1946-59. PMID: 22253473.
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    32. Leist M, Lidbury BA, Yang C, Hayden PJ, Kelm JM, Ringeissen S, Detroyer A, Meunier JR, Rathman JF, Jackson GR, Stolper G, Hasiwa N. Novel technologies and an overall strategy to allow hazard assessment and risk prediction of chemicals, cosmetics, and drugs with animal-free methods. ALTEX. 2012; 29(4):373-88. PMID: 23138508.
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    33. Jackson GR, Scott IU, Quillen DA, Walter LE, Gardner TW. Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy. Br J Ophthalmol. 2012 May; 96(5):699-703. PMID: 22174096.
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    34. Clos AL, Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Jackson GR, Kelly B, Beachkofsky TM, Kayed R. Formation of immunoglobulin light chain amyloid oligomers in primary cutaneous nodular amyloidosis. Br J Dermatol. 2011 Dec; 165(6):1349-54. PMID: 21729025.
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    35. Ambegaokar SS, Jackson GR. Functional genomic screen and network analysis reveal novel modifiers of tauopathy dissociated from tau phosphorylation. Hum Mol Genet. 2011 Dec 15; 20(24):4947-77. PMID: 21949350.
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    36. Lasagna-Reeves CA, Castillo-Carranza DL, Jackson GR, Kayed R. Tau oligomers as potential targets for immunotherapy for Alzheimer's disease and tauopathies. Curr Alzheimer Res. 2011 Sep; 8(6):659-65. PMID: 21605039.
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    37. Clos AL, Lasagna-Reeves CA, Kelly B, Wagner R, Wilkerson M, Jackson GR, Kayed R. Role of oligomers in the amyloidogenesis of primary cutaneous amyloidosis. J Am Acad Dermatol. 2011 Nov; 65(5):1023-31. PMID: 21669474.
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    38. Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Clos AL, Jackson GR, Kayed R. Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. Mol Neurodegener. 2011 Jun 06; 6:39. PMID: 21645391.
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    39. Hackett TL, Singhera GK, Shaheen F, Hayden P, Jackson GR, Hegele RG, Van Eeden S, Bai TR, Dorscheid DR, Knight DA. Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution. Am J Respir Cell Mol Biol. 2011 Nov; 45(5):1090-100. PMID: 21642587.
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    40. Kayed R, Jackson GR, Estes DM, Barrett AD. Alzheimers disease: review of emerging treatment role for intravenous immunoglobulins. J Cent Nerv Syst Dis. 2011; 3:67-73. PMID: 23861639.
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    41. Holfort SK, Nørgaard K, Jackson GR, Hommel E, Madsbad S, Munch IC, Klemp K, Sander B, Larsen M. Retinal function in relation to improved glycaemic control in type 1 diabetes. Diabetologia. 2011 Jul; 54(7):1853-61. PMID: 21516521.
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    42. Chang YC, Hung WT, Chang YC, Chang HC, Wu CL, Chiang AS, Jackson GR, Sang TK. Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model. PLoS Genet. 2011 Feb 03; 7(2):e1001288. PMID: 21304887.
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    43. Bakhoum MF, Jackson GR. Demise of the flies: why Drosophila models still matter. Prog Mol Biol Transl Sci. 2011; 100:483-98. PMID: 21377634.
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    44. Lasagna-Reeves CA, Castillo-Carranza DL, Guerrero-Muoz MJ, Jackson GR, Kayed R. Preparation and characterization of neurotoxic tau oligomers. Biochemistry. 2010 Nov 30; 49(47):10039-41. PMID: 21047142.
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    45. Clos AL, Lasagna-Reeves CA, Wagner R, Kelly B, Jackson GR, Kayed R. Therapeutic removal of amyloid deposits in cutaneous amyloidosis by localised intra-lesional injections of anti-amyloid antibodies. Exp Dermatol. 2010 Oct; 19(10):904-11. PMID: 20626464.
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    46. Lasagna-Reeves CA, Clos AL, Midoro-Hiriuti T, Goldblum RM, Jackson GR, Kayed R. Inhaled insulin forms toxic pulmonary amyloid aggregates. Endocrinology. 2010 Oct; 151(10):4717-24. PMID: 20685871.
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    47. Ambegaokar SS, Jackson GR. Interaction between eye pigment genes and tau-induced neurodegeneration in Drosophila melanogaster. Genetics. 2010 Sep; 186(1):435-42. PMID: 20592261.
      View in: PubMed
    48. Ambegaokar SS, Roy B, Jackson GR. Neurodegenerative models in Drosophila: polyglutamine disorders, Parkinson disease, and amyotrophic lateral sclerosis. Neurobiol Dis. 2010 Oct; 40(1):29-39. PMID: 20561920.
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    49. Barrett AD, Kayed R, Jackson GR, Cunningham KA. New vaccine development for chronic brain disease. Neuropsychopharmacology. 2010 Jan; 35(1):354. PMID: 20010720.
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    50. Kuo SH, Jackson GR. Emerging subspecialties in neurology: translational research in movement disorders. Neurology. 2009 Aug 25; 73(8):e40-1. PMID: 19704074.
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    51. Hayden PJ, Petrali JP, Stolper G, Hamilton TA, Jackson GR, Wertz PW, Ito S, Smith WJ, Klausner M. Microvesicating effects of sulfur mustard on an in vitro human skin model. Toxicol In Vitro. 2009 Oct; 23(7):1396-405. PMID: 19619636.
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    52. Kayed R, Jackson GR. Prefilament tau species as potential targets for immunotherapy for Alzheimer disease and related disorders. Curr Opin Immunol. 2009 Jun; 21(3):359-63. PMID: 19482462.
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    53. Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. J Neurosci. 2009 Feb 18; 29(7):1962-76. PMID: 19228951.
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    54. Chatterjee S, Sang TK, Lawless GM, Jackson GR. Dissociation of tau toxicity and phosphorylation: role of GSK-3beta, MARK and Cdk5 in a Drosophila model. Hum Mol Genet. 2009 Jan 01; 18(1):164-77. PMID: 18930955.
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    55. Schaffer BA, Bertram L, Miller BL, Mullin K, Weintraub S, Johnson N, Bigio EH, Mesulam M, Wiedau-Pazos M, Jackson GR, Cummings JL, Cantor RM, Levey AI, Tanzi RE, Geschwind DH. Association of GSK3B with Alzheimer disease and frontotemporal dementia. Arch Neurol. 2008 Oct; 65(10):1368-74. PMID: 18852354.
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    56. Ratnaparkhi A, Lawless GM, Schweizer FE, Golshani P, Jackson GR. A Drosophila model of ALS: human ALS-associated mutation in VAP33A suggests a dominant negative mechanism. PLoS One. 2008 Jun 04; 3(6):e2334. PMID: 18523548.
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    57. Jackson GR. Guide to understanding Drosophila models of neurodegenerative diseases. PLoS Biol. 2008 Feb; 6(2):e53. PMID: 18303955.
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    58. Sang TK, Chang HY, Lawless GM, Ratnaparkhi A, Mee L, Ackerson LC, Maidment NT, Krantz DE, Jackson GR. A Drosophila model of mutant human parkin-induced toxicity demonstrates selective loss of dopaminergic neurons and dependence on cellular dopamine. J Neurosci. 2007 Jan 31; 27(5):981-92. PMID: 17267552.
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    59. Sengupta S, Horowitz PM, Karsten SL, Jackson GR, Geschwind DH, Fu Y, Berry RW, Binder LI. Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro. Biochemistry. 2006 Dec 19; 45(50):15111-9. PMID: 17154549.
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    60. Slepko N, Bhattacharyya AM, Jackson GR, Steffan JS, Marsh JL, Thompson LM, Wetzel R. Normal-repeat-length polyglutamine peptides accelerate aggregation nucleation and cytotoxicity of expanded polyglutamine proteins. Proc Natl Acad Sci U S A. 2006 Sep 26; 103(39):14367-72. PMID: 16980414.
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    61. Karsten SL, Sang TK, Gehman LT, Chatterjee S, Liu J, Lawless GM, Sengupta S, Berry RW, Pomakian J, Oh HS, Schulz C, Hui KS, Wiedau-Pazos M, Vinters HV, Binder LI, Geschwind DH, Jackson GR. A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration. Neuron. 2006 Sep 07; 51(5):549-60. PMID: 16950154.
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    62. Sang TK, Jackson GR. Drosophila models of neurodegenerative disease. NeuroRx. 2005 Jul; 2(3):438-46. PMID: 16389307.
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    63. Mee L, Honkala H, Kopra O, Vesa J, Finnilä S, Visapää I, Sang TK, Jackson GR, Salonen R, Kestilä M, Peltonen L. Hydrolethalus syndrome is caused by a missense mutation in a novel gene HYLS1. Hum Mol Genet. 2005 Jun 01; 14(11):1475-88. PMID: 15843405.
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    64. Sang TK, Li C, Liu W, Rodriguez A, Abrams JM, Zipursky SL, Jackson GR. Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis. Hum Mol Genet. 2005 Feb 01; 14(3):357-72. PMID: 15590702.
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    65. Raychowdhury MK, Ibarra C, Damiano A, Jackson GR, Smith PR, McLaughlin M, Prat AG, Ausiello DA, Lader AS, Cantiello HF. Characterization of Na+-permeable cation channels in LLC-PK1 renal epithelial cells. J Biol Chem. 2004 May 07; 279(19):20137-46. PMID: 14982925.
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    66. Jackson GR, Wiedau-Pazos M, Sang TK, Wagle N, Brown CA, Massachi S, Geschwind DH. Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron. 2002 May 16; 34(4):509-19. PMID: 12062036.
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    67. Steffan JS, Bodai L, Pallos J, Poelman M, McCampbell A, Apostol BL, Kazantsev A, Schmidt E, Zhu YZ, Greenwald M, Kurokawa R, Housman DE, Jackson GR, Marsh JL, Thompson LM. Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. Nature. 2001 Oct 18; 413(6857):739-43. PMID: 11607033.
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    68. Owsley C, Jackson GR, White M, Feist R, Edwards D. Delays in rod-mediated dark adaptation in early age-related maculopathy. Ophthalmology. 2001 Jul; 108(7):1196-202. PMID: 11425675.
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    69. Lader AS, Prat AG, Jackson GR, Chervinsky KL, Lapey A, Kinane TB, Cantiello HF. Increased circulating levels of plasma ATP in cystic fibrosis patients. Clin Physiol. 2000 Sep; 20(5):348-53. PMID: 10971545.
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    70. Lader AS, Wang Y, Jackson GR, Borkan SC, Cantiello HF. cAMP-activated anion conductance is associated with expression of CFTR in neonatal mouse cardiac myocytes. Am J Physiol Cell Physiol. 2000 Feb; 278(2):C436-50. PMID: 10666040.
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    71. Jackson GR, Owsley C. Scotopic sensitivity during adulthood. Vision Res. 2000; 40(18):2467-73. PMID: 10915886.
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    72. Owsley C, Jackson GR, Cideciyan AV, Huang Y, Fine SL, Ho AC, Maguire MG, Lolley V, Jacobson SG. Psychophysical evidence for rod vulnerability in age-related macular degeneration. Invest Ophthalmol Vis Sci. 2000 Jan; 41(1):267-73. PMID: 10634630.
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    73. Prat AG, Cunningham CC, Jackson GR, Borkan SC, Wang Y, Ausiello DA, Cantiello HF. Actin filament organization is required for proper cAMP-dependent activation of CFTR. Am J Physiol. 1999 12; 277(6):C1160-9. PMID: 10600767.
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    74. McGwin G, Jackson GR, Owsley C. Using nonlinear regression to estimate parameters of dark adaptation. Behav Res Methods Instrum Comput. 1999 Nov; 31(4):712-7. PMID: 10633991.
      View in: PubMed
    75. Jackson GR, Owsley C, McGwin G. Aging and dark adaptation. Vision Res. 1999 Nov; 39(23):3975-82. PMID: 10748929.
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    76. Jackson GR, Owsley C, Cordle EP, Finley CD. Aging and scotopic sensitivity. Vision Res. 1998 Nov; 38(22):3655-62. PMID: 9893796.
      View in: PubMed
    77. Jackson GR, Salecker I, Dong X, Yao X, Arnheim N, Faber PW, MacDonald ME, Zipursky SL. Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons. Neuron. 1998 Sep; 21(3):633-42. PMID: 9768849.
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    78. Cantiello HF, Jackson GR, Grosman CF, Prat AG, Borkan SC, Wang Y, Reisin IL, O'Riordan CR, Ausiello DA. Electrodiffusional ATP movement through the cystic fibrosis transmembrane conductance regulator. Am J Physiol. 1998 03; 274(3):C799-809. PMID: 9530112.
      View in: PubMed
    79. Bosch I, Jackson GR, Croop JM, Cantiello HF. Expression of Drosophila melanogaster P-glycoproteins is associated with ATP channel activity. Am J Physiol. 1996 Nov; 271(5 Pt 1):C1527-38. PMID: 8944636.
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    80. Prat AG, Holtzman EJ, Brown D, Cunningham CC, Reisin IL, Kleyman TR, McLaughlin M, Jackson GR, Lydon J, Cantiello HF. Renal epithelial protein (Apx) is an actin cytoskeleton-regulated Na+ channel. J Biol Chem. 1996 Jul 26; 271(30):18045-53. PMID: 8663566.
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    81. Sampath D, Jackson GR, Werrbach-Perez K, Perez-Polo JR. Effects of nerve growth factor on glutathione peroxidase and catalase in PC12 cells. J Neurochem. 1994 Jun; 62(6):2476-9. PMID: 8189251.
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    82. Jackson GR, Sampath D, Werrbach-Perez K, Perez-Polo JR. Effects of nerve growth factor on catalase and glutathione peroxidase in a hydrogen peroxide-resistant pheochromocytoma subclone. Brain Res. 1994 Jan 14; 634(1):69-76. PMID: 8156393.
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    83. Jackson GR, Werrbach-Perez K, Pan Z, Sampath D, Perez-Polo JR. Neurotrophin regulation of energy homeostasis in the central nervous system. Dev Neurosci. 1994; 16(5-6):285-90. PMID: 7768207.
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    84. Jackson GR, Werrbach-Perez K, Ezell EL, Post JF, Perez-Polo JR. Nerve growth factor effects on pyridine nucleotides after oxidant injury of rat pheochromocytoma cells. Brain Res. 1992 Oct 02; 592(1-2):239-48. PMID: 1450913.
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    85. Taglialatela G, Angelucci L, Ramacci MT, Werrbach-Perez K, Jackson GR, Perez-Polo JR. Stimulation of nerve growth factor receptors in PC12 by acetyl-L-carnitine. Biochem Pharmacol. 1992 Aug 04; 44(3):577-85. PMID: 1324679.
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    86. Foreman PJ, Taglialatela G, Jackson GR, Perez-Polo JR. Dexamethasone blocks nerve growth factor induction of nerve growth factor receptor mRNA in PC12 cells. J Neurosci Res. 1992 Jan; 31(1):52-7. PMID: 1319504.
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    87. Taglialatela G, Angelucci L, Ramacci MT, Werrbach-Perez K, Jackson GR, Perez-Polo JR. Acetyl-L-carnitine enhances the response of PC12 cells to nerve growth factor. Brain Res Dev Brain Res. 1991 Apr 24; 59(2):221-30. PMID: 1655307.
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    88. Jackson GR, Morgan BC, Werrbach-Perez K, Perez-Polo JR. Antioxidant effect of retinoic acid on PC12 rat pheochromocytoma. Int J Dev Neurosci. 1991; 9(2):161-70. PMID: 1647645.
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    89. Perez-Polo JR, Foreman PJ, Jackson GR, Shan D, Taglialatela G, Thorpe LW, Werrbach-Perez K. Nerve growth factor and neuronal cell death. Mol Neurobiol. 1990 Spring-Summer; 4(1-2):57-91. PMID: 2076219.
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    90. Jackson GR, Apffel L, Werrbach-Perez K, Perez-Polo JR. Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury. I. Stimulation of hydrogen peroxide resistance. J Neurosci Res. 1990 Mar; 25(3):360-8. PMID: 2325161.
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    91. Jackson GR, Werrbach-Perez K, Perez-Polo JR. Role of nerve growth factor in oxidant-antioxidant balance and neuronal injury. II. A conditioning lesion paradigm. J Neurosci Res. 1990 Mar; 25(3):369-74. PMID: 2325162.
      View in: PubMed
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