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EDWARD S CHEN

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Human Genetics
DivisionMolecular & Human Genetics
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    F32HL010068     (CHEN, EDWARD S)Dec 30, 1998
    NIH/NHLBI
    CYTOKINE EXPRESSION IN INDUCED PULMONARY FIBROSIS
    Role: Principal Investigator

    K08HL071100     (CHEN, EDWARD S)Aug 4, 2003 - Jul 31, 2008
    NIH/NHLBI
    Interferon-gamma regulation of bleomycin pulmonary toxicity
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cao Y, Tokita MJ, Chen ES, Ghosh R, Chen T, Feng Y, Gorman E, Gibellini F, Ward PA, Braxton A, Wang X, Meng L, Xiao R, Bi W, Xia F, Eng CM, Yang Y, Gambin T, Shaw C, Liu P, Stankiewicz P. A clinical survey of mosaic single nucleotide variants in disease-causing genes detected by exome sequencing. Genome Med. 2019 Jul 26; 11(1):48. PMID: 31349857.
      View in: PubMed
    2. Madan N, Ghazi AR, Kong X, Chen ES, Shaw CA, Edelstein LC. Functionalization of CD36 cardiovascular disease and expression associated variants by interdisciplinary high throughput analysis. PLoS Genet. 2019 Jul; 15(7):e1008287. PMID: 31344026.
      View in: PubMed
    3. Beck CR, Carvalho CMB, Akdemir ZC, Sedlazeck FJ, Song X, Meng Q, Hu J, Doddapaneni H, Chong Z, Chen ES, Thornton PC, Liu P, Yuan B, Withers M, Jhangiani SN, Kalra D, Walker K, English AC, Han Y, Chen K, Muzny DM, Ira G, Shaw CA, Gibbs RA, Hastings PJ, Lupski JR. Megabase Length Hypermutation Accompanies Human Structural Variation at 17p11.2. Cell. 2019 Mar 07; 176(6):1310-1324.e10. PMID: 30827684.
      View in: PubMed
    4. Lindner BK, Gilmore VT, Kruer RM, Alvanzo AA, Chen ES, Murray P, Niessen T, Perrin K, Rastegar DA, Young S, Jarrell AS. Evaluation of the Brief Alcohol Withdrawal Scale Protocol at an Academic Medical Center. J Addict Med. 2019 Feb 06. PMID: 30741834.
      View in: PubMed
    5. Chen ECM, Chen ES. Electron affinities from gas chromatography electron capture detector and negative ion mass spectrometry responses and complementary methods. J Chromatogr A. 2018 Oct 26; 1573:1-17. PMID: 30219237.
      View in: PubMed
    6. Ghazi AR, Chen ES, Henke DM, Madan N, Edelstein LC, Shaw CA. Design tools for MPRA experiments. Bioinformatics. 2018 08 01; 34(15):2682-2683. PMID: 30052913.
      View in: PubMed
    7. Chen ES, Chen ECM. Electron affinities of substituted nitrobenzenes from negative ion mass spectrometry lifetimes and literature electron affinities. Rapid Commun Mass Spectrom. 2018 04 15; 32(7):604-606. PMID: 29396993.
      View in: PubMed
    8. Crawford TC, Okada DR, Magruder JT, Fraser C, Patel N, Houston BA, Whitman GJ, Mandal K, Zehr KJ, Higgins RS, Chen ES, Tandri H, Kasper EK, Tedford RJ, Russell SD, Gilotra NA. A Contemporary Analysis of Heart Transplantation and Bridge-to-Transplant Mechanical Circulatory Support Outcomes in Cardiac Sarcoidosis. J Card Fail. 2018 Jun; 24(6):384-391. PMID: 29482029.
      View in: PubMed
    9. Chen ES. Reassessing Th1 versus Th17.1 in sarcoidosis: new tricks for old dogma. Eur Respir J. 2018 03; 51(3). PMID: 29496788.
      View in: PubMed
    10. Chen ES, Chen ECM. Comment on: Negative ions, molecular electron affinity and orbital structure of cata-condensed polycyclic aromatic hydrocarbons by Rustem V. Khatymov, Mars V. Muftakhov and Pavel V. Shchukin. Rapid Commun Mass Spectrom. 2018 Feb 15; 32(3):230-234. PMID: 29082631.
      View in: PubMed
    11. Galiatsatos P, Brigham EP, Pietri J, Littleton K, Hwang S, Grant MC, Hansel NN, Chen ES. The effect of community socioeconomic status on sepsis-attributable mortality. J Crit Care. 2018 08; 46:129-133. PMID: 29370964.
      View in: PubMed
    12. Patterson KC, Chen ES. The Pathogenesis of Pulmonary Sarcoidosis and Implications for Treatment. Chest. 2018 Jun; 153(6):1432-1442. PMID: 29224832.
      View in: PubMed
    13. Moller DR, Rybicki BA, Hamzeh NY, Montgomery CG, Chen ES, Drake W, Fontenot AP. Genetic, Immunologic, and Environmental Basis of Sarcoidosis. Ann Am Thorac Soc. 2017 Dec; 14(Supplement_6):S429-S436. PMID: 29073364.
      View in: PubMed
    14. Chareonthaitawee P, Beanlands RS, Chen W, Dorbala S, Miller EJ, Murthy VL, Birnie DH, Chen ES, Cooper LT, Tung RH, White ES, Borges-Neto S, Di Carli MF, Gropler RJ, Ruddy TD, Schindler TH, Blankstein R. Joint SNMMI-ASNC expert consensus document on the role of 18F-FDG PET/CT in cardiac sarcoid detection and therapy monitoring. J Nucl Cardiol. 2017 10; 24(5):1741-1758. PMID: 28770463.
      View in: PubMed
    15. Chareonthaitawee P, Beanlands RS, Chen W, Dorbala S, Miller EJ, Murthy VL, Birnie DH, Chen ES, Cooper LT, Tung RH, White ES, Borges-Neto S, Di Carli MF, Gropler RJ, Ruddy TD, Schindler TH, Blankstein R. Joint SNMMI-ASNC Expert Consensus Document on the Role of 18F-FDG PET/CT in Cardiac Sarcoid Detection and Therapy Monitoring. J Nucl Med. 2017 08; 58(8):1341-1353. PMID: 28765228.
      View in: PubMed
    16. Rastegar DA, Applewhite D, Alvanzo AAH, Welsh C, Niessen T, Chen ES. Development and implementation of an alcohol withdrawal protocol using a 5-item scale, the Brief Alcohol Withdrawal Scale (BAWS). Subst Abus. 2017 Oct-Dec; 38(4):394-400. PMID: 28699845.
      View in: PubMed
    17. Xu X, De Angelis C, Burke KA, Nardone A, Hu H, Qin L, Veeraraghavan J, Sethunath V, Heiser LM, Wang N, Ng CKY, Chen ES, Renwick A, Wang T, Nanda S, Shea M, Mitchell T, Rajendran M, Waters I, Zabransky DJ, Scott KL, Gutierrez C, Nagi C, Geyer FC, Chamness GC, Park BH, Shaw CA, Hilsenbeck SG, Rimawi MF, Gray JW, Weigelt B, Reis-Filho JS, Osborne CK, Schiff R. HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer. Clin Cancer Res. 2017 Sep 01; 23(17):5123-5134. PMID: 28487443.
      View in: PubMed
    18. Kruse MJ, Kovell L, Kasper EK, Pomper MG, Moller DR, Solnes L, Chen ES, Schindler TH. Myocardial Blood Flow and Inflammatory Cardiac Sarcoidosis. JACC Cardiovasc Imaging. 2017 02; 10(2):157-167. PMID: 28109920.
      View in: PubMed
    19. Loviglio MN, Beck CR, White JJ, Leleu M, Harel T, Guex N, Niknejad A, Bi W, Chen ES, Crespo I, Yan J, Charng WL, Gu S, Fang P, Coban-Akdemir Z, Shaw CA, Jhangiani SN, Muzny DM, Gibbs RA, Rougemont J, Xenarios I, Lupski JR, Reymond A. Identification of a RAI1-associated disease network through integration of exome sequencing, transcriptomics, and 3D genomics. Genome Med. 2016 11 01; 8(1):105. PMID: 27799067.
      View in: PubMed
    20. Chen ES. Innate immunity in sarcoidosis pathobiology. Curr Opin Pulm Med. 2016 09; 22(5):469-75. PMID: 27387100.
      View in: PubMed
    21. Chen ES, Chen EC, Rosenthal R, Chang S, Herder C. Mass spectrometric determination of Morse parameters for the fifty-four superoxide states dissociating to the lowest limit. Rapid Commun Mass Spectrom. 2016 06 30; 30(12):1384-90. PMID: 27197030.
      View in: PubMed
    22. Simon LM, Chen ES, Edelstein LC, Kong X, Bhatlekar S, Rigoutsos I, Bray PF, Shaw CA. Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2. Am J Hum Genet. 2016 05 05; 98(5):883-897. PMID: 27132591.
      View in: PubMed
    23. James RA, Campbell IM, Chen ES, Boone PM, Rao MA, Bainbridge MN, Lupski JR, Yang Y, Eng CM, Posey JE, Shaw CA. A visual and curatorial approach to clinical variant prioritization and disease gene discovery in genome-wide diagnostics. Genome Med. 2016 Feb 02; 8(1):13. PMID: 26838676.
      View in: PubMed
    24. Chen ES, Moller DR. Etiologies of Sarcoidosis. Clin Rev Allergy Immunol. 2015 Aug; 49(1):6-18. PMID: 25771769.
      View in: PubMed
    25. Chen ES, Chen EC, Barrera LK, Herder C. Atmospheric pressure anion mass spectrometry: electron affinities and activation energies of thermal electron attachment - perfluoromethylcyclohexane, C7F14. Rapid Commun Mass Spectrom. 2015 Jun 30; 29(12):1165-77. PMID: 25981547.
      View in: PubMed
    26. Chen ES, Keith H, Lim T, Pham D, Rosenthal R, Herder C, Pai S, Flores RA, Chen EC. Hylleraas hydride binding energy: diatomic electron affinities. J Mol Model. 2015 Apr; 21(4):79. PMID: 25758340.
      View in: PubMed
    27. Edelstein LC, Simon LM, Lindsay CR, Kong X, Teruel-Montoya R, Tourdot BE, Chen ES, Ma L, Coughlin S, Nieman M, Holinstat M, Shaw CA, Bray PF. Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race. Blood. 2014 Nov 27; 124(23):3450-8. PMID: 25293779.
      View in: PubMed
    28. Campbell IM, James RA, Chen ES, Shaw CA. NetComm: a network analysis tool based on communicability. Bioinformatics. 2014 Dec 01; 30(23):3387-9. PMID: 25123899.
      View in: PubMed
    29. Chen ES, Moller DR. Etiologic role of infectious agents. Semin Respir Crit Care Med. 2014 Jun; 35(3):285-95. PMID: 25007081.
      View in: PubMed
    30. Chen ES, Chen EC. Negative surface ionization electron affinities and activation energies of SF(n). Rapid Commun Mass Spectrom. 2014 Mar 15; 28(5):527-35. PMID: 24497291.
      View in: PubMed
    31. Simon LM, Edelstein LC, Nagalla S, Woodley AB, Chen ES, Kong X, Ma L, Fortina P, Kunapuli S, Holinstat M, McKenzie SE, Dong JF, Shaw CA, Bray PF. Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics. Blood. 2014 Apr 17; 123(16):e37-45. PMID: 24523238.
      View in: PubMed
    32. Edelstein LC, Simon LM, Montoya RT, Holinstat M, Chen ES, Bergeron A, Kong X, Nagalla S, Mohandas N, Cohen DE, Dong JF, Shaw C, Bray PF. Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c. Nat Med. 2013 Dec; 19(12):1609-16. PMID: 24216752.
      View in: PubMed
    33. Zhang X, Claerhout S, Prat A, Dobrolecki LE, Petrovic I, Lai Q, Landis MD, Wiechmann L, Schiff R, Giuliano M, Wong H, Fuqua SW, Contreras A, Gutierrez C, Huang J, Mao S, Pavlick AC, Froehlich AM, Wu MF, Tsimelzon A, Hilsenbeck SG, Chen ES, Zuloaga P, Shaw CA, Rimawi MF, Perou CM, Mills GB, Chang JC, Lewis MT. A renewable tissue resource of phenotypically stable, biologically and ethnically diverse, patient-derived human breast cancer xenograft models. Cancer Res. 2013 Aug 01; 73(15):4885-97. PMID: 23737486.
      View in: PubMed
    34. Darlington Y, Jeong JW, Lee KY, Franco HL, Chen ES, McOwiti A, Mistretta TA, Steffen D, Becnel L, DeMayo FJ. Research resource: the Endometrium Database Resource (EDR). Mol Endocrinol. 2013 Mar; 27(3):548-54. PMID: 23340253.
      View in: PubMed
    35. Chen ES, Chen EC. Ground state electron affinities based on " Generation of negative ions from SF6 gas by means of hot surface ionization": A. Pelc, Rapid Commun. Mass Spectrom. 2012, 26, 577-582. Rapid Commun Mass Spectrom. 2013 Jan 15; 27(1):281-3. PMID: 23239343.
      View in: PubMed
    36. Zhou T, Zhang W, Sweiss NJ, Chen ES, Moller DR, Knox KS, Ma SF, Wade MS, Noth I, Machado RF, Garcia JG. Peripheral blood gene expression as a novel genomic biomarker in complicated sarcoidosis. PLoS One. 2012; 7(9):e44818. PMID: 22984568.
      View in: PubMed
    37. James RA, Rao MM, Chen ES, Goodell MA, Shaw CA. The Hematopoietic Expression Viewer: expanding mobile apps as a scientific tool. Bioinformatics. 2012 Jul 15; 28(14):1941-2. PMID: 22576171.
      View in: PubMed
    38. Chen ES, Chen EC. Comment on "Ab initio molecular dynamics calculation of ion hydration free energies" [J. Chem. Phys. 130, 204507 (2009)]. J Chem Phys. 2010 Jul 28; 133(4):047103; author reply 047104. PMID: 20687695.
      View in: PubMed
    39. Ochsner SA, Steffen DL, Hilsenbeck SG, Chen ES, Watkins C, McKenna NJ. GEMS (Gene Expression MetaSignatures), a Web resource for querying meta-analysis of expression microarray datasets: 17beta-estradiol in MCF-7 cells. Cancer Res. 2009 Jan 01; 69(1):23-6. PMID: 19117983.
      View in: PubMed
    40. Chen ES, Wahlström J, Song Z, Willett MH, Wikén M, Yung RC, West EE, McDyer JF, Zhang Y, Eklund A, Grunewald J, Moller DR. T cell responses to mycobacterial catalase-peroxidase profile a pathogenic antigen in systemic sarcoidosis. J Immunol. 2008 Dec 15; 181(12):8784-96. PMID: 19050300.
      View in: PubMed
    41. Dhar SU, Scaglia F, Li FY, Smith L, Barshop BA, Eng CM, Haas RH, Hunter JV, Lotze T, Maranda B, Willis M, Abdenur JE, Chen E, O'Brien W, Wong LJ. Expanded clinical and molecular spectrum of guanidinoacetate methyltransferase (GAMT) deficiency. Mol Genet Metab. 2009 Jan; 96(1):38-43. PMID: 19027335.
      View in: PubMed
    42. Chen EC, Wiley JR, Chen ES. The electron affinities of deprotonated adenine, guanine, cytosine, uracil, and thymine. Nucleosides Nucleotides Nucleic Acids. 2008 May; 27(5):506-24. PMID: 18569789.
      View in: PubMed
    43. ECM Chen, ES Chen. Thermal Electrons and Watson Crick AT(-). Chemical Physics Letters. 2007; 435(4):331-335.
    44. ECM Chen, C Herder, ES Chen. The experimental and theoretical gas phase acidities of adenine, guanine, cytosine, uracil, thymine and halouracils. Journal of Molecular Structure. 2006; 798(1):126-133.
    45. Chen EC, Chen ES. Molecular electron affinities and the calculation of the temperature dependence of the electron-capture detector response. J Chromatogr A. 2004 May 28; 1037(1-2):83-106. PMID: 15214661.
      View in: PubMed
    46. Chen EC, Chen ES. Electron attachment to C(2)Cl(4) and Trojan horse ionization. J Chem Phys. 2004 Apr 01; 120(13):6312-3. PMID: 15267519.
      View in: PubMed
    47. Chen ES, Chen EC. Electron-capture detector and multiple negative ions of aromatic hydrocarbons. J Chromatogr A. 2002 Apr 05; 952(1-2):173-83. PMID: 12064529.
      View in: PubMed
    48. Ruths DA, Chen ES, Ellis L. Arbor 3D: an interactive environment for examining phylogenetic and taxonomic trees in multiple dimensions. Bioinformatics. 2000 Nov; 16(11):1003-9. PMID: 11159311.
      View in: PubMed
    49. ECM Chen, ES Chen. Negative ion mass spectra, electron affinities, gas phase acidities, bond dissociation energies, and negative ion states of cytosine and thymine. The Journal of Physical Chemistry B. 2000; 104(32):7835-7844.
    50. Chen ES, Chen EC, Sane N, Shulze S. Classification of organic molecules to obtain electron affinities from half-wave reduction potentials: cytosine, uracil, thymine, guanine and adenine. Bioelectrochem Bioenerg. 1999 Feb; 48(1):69-78. PMID: 10228572.
      View in: PubMed
    51. Chen ES, Chen EC, Sane N. The electron affinities of the radicals formed by the loss of an aromatic hydrogen atom from adenine, guanine, cytosine, uracil, and thymine. Biochem Biophys Res Commun. 1998 May 08; 246(1):228-30. PMID: 9600097.
      View in: PubMed
    52. Parrish JE, Ciccodicola A, Wehhert M, Cox GF, Chen E, Nelson DL. A muscle-specific DNase I-like gene in human Xq28. Hum Mol Genet. 1995 Sep; 4(9):1557-64. PMID: 8541839.
      View in: PubMed
    53. Chen ES, Asano C, Davison DB. Parallel alignment of DNA sequences on the Connection Machine CM-2. Comput Appl Biosci. 1993 Jun; 9(3):375. PMID: 8324640.
      View in: PubMed
    54. Wiley JR, Robinson JM, Ehdaie S, Chen EC, Chen ES, Wentworth WE. The determination of absolute electron affinities of the purines and pyrimidines in DNA and RNA from reversible reduction potentials. Biochem Biophys Res Commun. 1991 Oct 31; 180(2):841-5. PMID: 1719971.
      View in: PubMed
    55. Chen EC, Chen ES, Wentworth WE. The role of electron donors and acceptors in base stacking in DNA and RNA. Biochem Biophys Res Commun. 1990 Aug 31; 171(1):97-101. PMID: 1697469.
      View in: PubMed
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