DANIEL LEUNG

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6701 FANNIN
Houston, TX 77030
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    Collapse education and training
    University of Oklahoma, Norman, OKBS1999Biochemistry
    University of Texas School of Medicine, San Antonio, TXMD2003Medicine
    Baylor College of Medicine/Texas Children's Hospital, Houston, TXResidency2006Pediatrics
    University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PAFellowship2009Gastroenterology, Hepatology & Nutrition
    Collapse awards and honors
    2019Best CME Course, Director of the 24th Annual SPLIT Meeting, Texas Children's Hospital
    2018Clinical Research Award, Clinical Research Center/BCM RRO
    2018Fellow , American Association of the Study of Liver Diseases
    2017Houstonia Top Doctors, Houstonia Magazine
    2016BCM Academy of Distinguished Educators, Baylor College of Medicine
    2015Top Doctors Rising Stars, Texas Monthly
    2014Fulbright & Jaworski L. L. P. Faculty Excellence in Teaching Award, Baylor College of Medicine
    2014Dr. George Ferry Most Outstanding GI Faculty Award , Texas Children's Hospital
    2014 - 2017Cystic Fibrosis Foundation DIGEST Award, Cystic Fibrosis Foundation
    2013Texas Children’s Pediatric Pilot Award, BCM/Texas Children's Hospital

    Collapse Overview 

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    Collapse research activities and funding
    U01DK103149     (SHNEIDER, BENJAMIN L.)Sep 10, 2014 - May 31, 2024
    NIH/NIDDK
    BCM/TCH CHOLESTATIC LIVER DISEASE CONSORTIUM
    Role: Co-Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Shiau H, Schraw JM, Cavallo L, Leung DH, Harpavat S, Lupo PJ, Shneider BL. Operational Definitions for Chronic Liver Disease Manifestations and Recurring Clinical Events in Biliary Atresia. J Pediatr Gastroenterol Nutr. 2020 Dec 09. PMID: 33306582.
      Citations:    Fields:    
    2. Goss MB, Munoz FM, Ruan W, Galván NTN, O'Mahony CA, Rana A, Cotton RT, Moreno NF, Heczey AA, Leung DH, Goss JA. Liver transplant in a recently COVID-19 positive child with hepatoblastoma. Pediatr Transplant. 2020 Sep 26; e13880. PMID: 32979013.
      Citations:    Fields:    
    3. Goss MB, Galván NTN, Ruan W, Munoz FM, Brewer ED, O'Mahony CA, Melicoff-Portillo E, Dreyer WJ, Miloh TA, Cigarroa FG, Ranch D, Yoeli D, Adams MA, Koohmaraie S, Harter DM, Rana A, Cotton RT, Carter B, Patel S, Moreno NF, Leung DH, Goss JA. The pediatric solid organ transplant experience with COVID-19: An initial multi-center, multi-organ case series. Pediatr Transplant. 2020 Sep 18; e13868. PMID: 32949098.
      Citations:    Fields:    
    4. Leung DH, Squires JE, Jhaveri R, Kerkar N, Lin CH, Mohan P, Murray KF, Gonzalez-Peralta RP, Roberts EA, Sundaram SS. Hepatitis C in 2020: A North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper. J Pediatr Gastroenterol Nutr. 2020 09; 71(3):407-417. PMID: 32826718.
      Citations:    Fields:    
    5. Shneider BL, Goodrich NP, Ye W, Sawyers C, Molleston JP, Merion RM, Leung DH, Karpen SJ, Kamath BM, Cavallo L, Wang K, Teckman JH, Squires JE, Sundaram SS, Rosenthal P, Romero R, Murray KF, Loomes KM, Jensen MK, Bezerra JA, Bass LM, Sokol RJ, Magee JC. Nonfasted Liver Stiffness Correlates with Liver Disease Parameters and Portal Hypertension in Pediatric Cholestatic Liver Disease. Hepatol Commun. 2020 Nov; 4(11):1694-1707. PMID: 33163838.
      Citations:    
    6. Shiau H, Guffey D, Loomes KM, Seidman C, Ragozzino E, Molleston JP, Schady D, Leung DH. Biopsy Validated Study of Biomarkers for Liver Fibrosis and Transplant Prediction in Inherited Cholestasis. Hepatol Commun. 2020 Oct; 4(10):1516-1526. PMID: 33024920.
      Citations:    
    7. Mercedes R, Brown J, Minard C, Tsai CM, Devaraj S, Munden M, Leung D. A Liver Biopsy Validation Pilot Study of Shear Wave Elastography, APRI, FIB-4, and Novel Serum Biomarkers for Liver Fibrosis Staging in Children With Chronic Viral Hepatitis. Glob Pediatr Health. 2020; 7:2333794X20938931. PMID: 32821773.
      Citations:    
    8. Rosenthal P, Narkewicz MR, Yao BB, Jolley CD, Lobritto SJ, Wen J, Molleston JP, Hsu EK, Jonas MM, Zha J, Liu L, Leung DH. Ombitasvir, Paritaprevir, Ritonavir, and Dasabuvir Mini-Tabs Plus Ribavirin for Children Aged 3-11 Years with Hepatitis C Genotype 1a. Adv Ther. 2020 07; 37(7):3299-3310. PMID: 32451952.
      Citations:    Fields:    
    9. Indolfi G, Fischler B, Gonzalez-Peralta RP, Ciocca M, Porta G, Neelam M, El-Guindi M, Kelly D, Ni YH, Sibal A, Leung DH, Chang MH. Comparison of Recommendations for Treatment of Chronic Hepatitis C Virus Infection in Children and Adolescents: A Position Paper of the Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2020 05; 70(5):711-717. PMID: 32205770.
      Citations: 1     Fields:    
    10. Burrage LC, Madan S, Li X, Ali S, Mohammad M, Stroup BM, Jiang MM, Cela R, Bertin T, Jin Z, Dai J, Guffey D, Finegold M, Nagamani S, Minard CG, Marini J, Masand P, Schady D, Shneider BL, Leung DH, Bali D, Lee B. Chronic liver disease and impaired hepatic glycogen metabolism in argininosuccinate lyase deficiency. JCI Insight. 2020 02 27; 5(4). PMID: 31990680.
      Citations:    Fields:    
    11. Siegel MJ, Freeman AJ, Ye W, Palermo JJ, Molleston JP, Paranjape SM, Stoll J, Leung DH, Masand P, Karmazyn B, Harned R, Ling SC, Navarro OM, Karnsakul W, Alazraki A, Schwarzenberg SJ, Seidel FG, Towbin A, Alonso EM, Nicholas JL, Murray KF, Otto RK, Sherker AH, Magee JC, Narkewicz MR. Heterogeneous Liver on Research Ultrasound Identifies Children with Cystic Fibrosis at High Risk of Advanced Liver Disease: Interim Results of a Prospective Observational Case-Controlled Study. J Pediatr. 2020 04; 219:62-69.e4. PMID: 32061406.
      Citations:    Fields:    Translation:Humans
    12. Kamath BM, Ye W, Goodrich NP, Loomes KM, Romero R, Heubi JE, Leung DH, Spinner NB, Piccoli DA, Alonso EM, Guthery SL, Karpen SJ, Mack CL, Molleston JP, Murray KF, Rosenthal P, Squires JE, Teckman J, Wang KS, Thompson R, Magee JC, Sokol RJ. Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Study. Hepatol Commun. 2020 Mar; 4(3):387-398. PMID: 33313463.
      Citations:    
    13. Hayden HS, Eng A, Pope CE, Brittnacher MJ, Vo AT, Weiss EJ, Hager KR, Martin BD, Leung DH, Heltshe SL, Borenstein E, Miller SI, Hoffman LR. Fecal dysbiosis in infants with cystic fibrosis is associated with early linear growth failure. Nat Med. 2020 02; 26(2):215-221. PMID: 31959989.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    14. Ling SC, Ye W, Leung DH, Navarro OM, Weymann A, Karnsakul W, Freeman AJ, Magee JC, Narkewicz MR. Liver Ultrasound Patterns in Children With Cystic Fibrosis Correlate With Noninvasive Tests of Liver Disease. J Pediatr Gastroenterol Nutr. 2019 09; 69(3):351-357. PMID: 31436672.
      Citations:    Fields:    Translation:Humans
    15. Freeman AJ, Sellers ZM, Mazariegos G, Kelly A, Saiman L, Mallory G, Ling SC, Narkewicz MR, Leung DH. A Multidisciplinary Approach to Pretransplant and Posttransplant Management of Cystic Fibrosis-Associated Liver Disease. Liver Transpl. 2019 04; 25(4):640-657. PMID: 30697907.
      Citations:    Fields:    Translation:Humans
    16. Lewindon PJ, Puertolas-Lopez MV, Ramm LE, Noble C, Pereira TN, Wixey JA, Hartel GF, Calvopina DA, Leung DH, Ramm GA. Accuracy of Transient Elastography Data Combined With APRI in Detection and Staging of Liver Disease in Pediatric Patients With Cystic Fibrosis. Clin Gastroenterol Hepatol. 2019 11; 17(12):2561-2569.e5. PMID: 30880274.
      Citations:    Fields:    Translation:Humans
    17. Goetz D, Kopp BT, Salvator A, Moore-Clingenpeel M, McCoy K, Leung DH, Kloster M, Ramsey BR, Heltshe SH, Borowitz D. Pulmonary findings in infants with cystic fibrosis during the first year of life: Results from the Baby Observational and Nutrition Study (BONUS) cohort study. Pediatr Pulmonol. 2019 05; 54(5):581-586. PMID: 30672141.
      Citations:    Fields:    Translation:Humans
    18. Cortes-Santiago N, Leung DH, Castro E, Finegold M, Wu H, Patel KR. Hepatic Steatosis Is Prevalent Following Orthotopic Liver Transplantation in Children With Cystic Fibrosis. J Pediatr Gastroenterol Nutr. 2019 01; 68(1):96-103. PMID: 30234762.
      Citations: 2     Fields:    Translation:Humans
    19. Calvopina DA, Chatfield MD, Weis A, Coleman MA, Fernandez-Rojo MA, Noble C, Ramm LE, Leung DH, Lewindon PJ, Ramm GA. MicroRNA Sequencing Identifies a Serum MicroRNA Panel, Which Combined With Aspartate Aminotransferase to Platelet Ratio Index Can Detect and Monitor Liver Disease in Pediatric Cystic Fibrosis. Hepatology. 2018 12; 68(6):2301-2316. PMID: 30014495.
      Citations: 3     Fields:    Translation:Humans
    20. Wu H, Vu M, Dhingra S, Ackah R, Goss JA, Rana A, Quintanilla N, Patel K, Leung DH. Obliterative Portal Venopathy Without Cirrhosis Is Prevalent in Pediatric Cystic Fibrosis Liver Disease With Portal Hypertension. Clin Gastroenterol Hepatol. 2019 09; 17(10):2134-2136. PMID: 30404037.
      Citations: 2     Fields:    Translation:Humans
    21. Leung DH, Wirth S, Yao BB, Viani RM, Gonzalez-Peralta RP, Jonas MM, Lobritto SJ, Narkewicz MR, Sokal E, Fortuny C, Hsu EK, Del Valle-Segarra A, Zha J, Larsen L, Liu L, Shuster DL, Cohen DE, Rosenthal P. Ombitasvir/Paritaprevir/Ritonavir With or Without Dasabuvir and With or Without Ribavirin for Adolescents With HCV Genotype 1 or 4. Hepatol Commun. 2018 Nov; 2(11):1311-1319. PMID: 30411078.
      Citations:    
    22. Shneider BL, Spino C, Kamath BM, Magee JC, Bass LM, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Murray KF, Loomes KM, Rosenthal P, Karpen SJ, Leung DH, Guthery SL, Thomas D, Sherker AH, Sokol RJ. Placebo-Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome. Hepatol Commun. 2018 Oct; 2(10):1184-1198. PMID: 30288474.
      Citations:    
    23. Mysore KR, Leung DH. Hepatitis B and C. Clin Liver Dis. 2018 11; 22(4):703-722. PMID: 30266158.
      Citations: 3     Fields:    Translation:Humans
    24. Coffey A, Leung DH, Quintanilla NM. Erythropoietic Protoporphyria: Initial Diagnosis With Cholestatic Liver Disease. Pediatrics. 2018 04; 141(Suppl 5):S445-S450. PMID: 29610169.
      Citations:    Fields:    Translation:Humans
    25. Gelfond D, Heltshe SL, Skalland M, Heubi JE, Kloster M, Leung DH, Ramsey BW, Borowitz D. Pancreatic Enzyme Replacement Therapy Use in Infants With Cystic Fibrosis Diagnosed by Newborn Screening. J Pediatr Gastroenterol Nutr. 2018 04; 66(4):657-663. PMID: 29176494.
      Citations:    Fields:    Translation:HumansPHPublic Health
    26. Ye W, Narkewicz MR, Leung DH, Karnsakul W, Murray KF, Alonso EM, Magee JC, Schwarzenberg SJ, Weymann A, Molleston JP. Variceal Hemorrhage and Adverse Liver Outcomes in Patients With Cystic Fibrosis Cirrhosis. J Pediatr Gastroenterol Nutr. 2018 01; 66(1):122-127. PMID: 28906321.
      Citations: 1     Fields:    Translation:Humans
    27. Leung DH, Narkewicz MR. Cystic Fibrosis-related cirrhosis. J Cyst Fibros. 2017 Nov; 16 Suppl 2:S50-S61. PMID: 28986027.
      Citations: 2     Fields:    Translation:Humans
    28. Leung DH, Heltshe SL, Borowitz D, Gelfond D, Kloster M, Heubi JE, Stalvey M, Ramsey BW. Effects of Diagnosis by Newborn Screening for Cystic Fibrosis on Weight and Length in the First Year of Life. JAMA Pediatr. 2017 06 01; 171(6):546-554. PMID: 28437538.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    29. Leung DH, Yimlamai D. The intestinal microbiome and paediatric liver disease. Lancet Gastroenterol Hepatol. 2017 06; 2(6):446-455. PMID: 28497760.
      Citations: 8     Fields:    Translation:Humans
    30. Leung DH. Hepatic fibrosis scores and serum biomarkers in pediatric hepatology. Clin Liver Dis (Hoboken). 2017 May; 9(5):125-130. PMID: 30992975.
      Citations:    
    31. Leung DH, Narang A, Minard CG, Hiremath G, Goss JA, Shepherd R. A 10-Year united network for organ sharing review of mortality and risk factors in young children awaiting liver transplantation. Liver Transpl. 2016 11; 22(11):1584-1592. PMID: 27541809.
      Citations: 6     Fields:    Translation:Humans
    32. Patel SS, Leung DH. Hepatitis B immunity in the pediatric liver transplant population. Curr Opin Pediatr. 2016 10; 28(5):653-8. PMID: 27367054.
      Citations: 1     Fields:    Translation:Humans
    33. Leung DH, Grand RJ. 50 Years Ago in TheJournal ofPediatrics: Macroscopic Cysts of the Pancreas in a Case of Cystic Fibrosis. J Pediatr. 2016 09; 176:133. PMID: 27568251.
      Citations:    Fields:    Translation:Humans
    34. Shneider BL, de Ville de Goyet J, Leung DH, Srivastava A, Ling SC, Duché M, McKiernan P, Superina R, Squires RH, Bosch J, Groszmann R, Sarin SK, de Franchis R, Mazariegos GV. Primary prophylaxis of variceal bleeding in children and the role of MesoRex Bypass: Summary of the Baveno VI Pediatric Satellite Symposium. Hepatology. 2016 Apr; 63(4):1368-80. PMID: 26358549.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    35. Amin MD, Harpavat S, Leung DH. Drug-induced liver injury in children. Curr Opin Pediatr. 2015 Oct; 27(5):625-33. PMID: 26208237.
      Citations: 2     Fields:    Translation:Humans
    36. Leung DH, Khan M, Minard CG, Guffey D, Ramm LE, Clouston AD, Miller G, Lewindon PJ, Shepherd RW, Ramm GA. Aspartate aminotransferase to platelet ratio and fibrosis-4 as biomarkers in biopsy-validated pediatric cystic fibrosis liver disease. Hepatology. 2015 Nov; 62(5):1576-83. PMID: 26223427.
      Citations: 13     Fields:    Translation:Humans
    37. Xue MM, Glenn JS, Leung DH. Hepatitis D in Children. J Pediatr Gastroenterol Nutr. 2015 Sep; 61(3):271-81. PMID: 25988557.
      Citations: 2     Fields:    Translation:HumansCells
    38. Leung DH, Ye W, Molleston JP, Weymann A, Ling S, Paranjape SM, Romero R, Schwarzenberg SJ, Palermo J, Alonso EM, Murray KF, Marshall BC, Sherker AH, Siegel MJ, Krishnamurthy R, Harned R, Karmazyn B, Magee JC, Narkewicz MR. Baseline Ultrasound and Clinical Correlates in Children with Cystic Fibrosis. J Pediatr. 2015 Oct; 167(4):862-868.e2. PMID: 26254836.
      Citations: 3     Fields:    Translation:HumansCells
    39. Coburn-Miller C, Casey S, Luong Q, Cameron N, Hocevar-Trnka J, Leung DH, Gelfond D, Heubi JE, Ramsey B, Borowitz D. Standardization of Research-Quality Anthropometric Measurement of Infants and Implementation in a Multicenter Study. Clin Transl Sci. 2015 Aug; 8(4):330-3. PMID: 26053284.
      Citations: 4     Fields:    Translation:Humans
    40. Mann M, Goetz D, Leung DH, Borowitz D. Starting an academic career and starting a family: challenges and some potential solutions. J Pediatr. 2014 Sep; 165(3):430-1. PMID: 25152148.
      Citations:    Fields:    Translation:Humans
    41. Khaderi S, Shepherd R, Goss JA, Leung DH. Hepatitis C in the pediatric population: transmission, natural history, treatment and liver transplantation. World J Gastroenterol. 2014 Aug 28; 20(32):11281-6. PMID: 25170212.
      Citations: 3     Fields:    Translation:HumansCells
    42. Heltshe SL, Borowitz DS, Leung DH, Ramsey B, Mayer-Hamblett N. Early attained weight and length predict growth faltering better than velocity measures in infants with CF. J Cyst Fibros. 2014 Dec; 13(6):723-9. PMID: 24917114.
      Citations: 3     Fields:    Translation:Humans
    43. Xue M, Masand P, Thompson P, Finegold M, Leung DH. Angiosarcoma successfully treated with liver transplantation and sirolimus. Pediatr Transplant. 2014 Jun; 18(4):E114-9. PMID: 24641525.
      Citations: 3     Fields:    Translation:Humans
    44. Brackett J, Schafer ES, Leung DH, Bernhardt MB. Use of allopurinol in children with acute lymphoblastic leukemia to reduce skewed thiopurine metabolism. Pediatr Blood Cancer. 2014 Jun; 61(6):1114-7. PMID: 24376133.
      Citations: 7     Fields:    Translation:Humans
    45. Leung DH, Ahamba DC, Pillai LN, Khan MF, Smith EO, Mahoney DH. Unrecognized hepatitis B in pre-screened children with hematologic and oncologic conditions. Pediatr Blood Cancer. 2014 May; 61(5):865-8. PMID: 24249385.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    46. Mack CL, Gonzalez-Peralta RP, Gupta N, Leung D, Narkewicz MR, Roberts EA, Rosenthal P, Schwarz KB. NASPGHAN practice guidelines: Diagnosis and management of hepatitis C infection in infants, children, and adolescents. J Pediatr Gastroenterol Nutr. 2012 Jun; 54(6):838-55. PMID: 22487950.
      Citations: 46     Fields:    Translation:HumansCells
    47. Leung DH, Chung CT. Cases in pediatric gastroenterology from The Children's Hospital of Philadelphia: a 2-year-old boy with diarrhea, failure to thrive, and hepatomegaly. Medscape J Med. 2009; 11(1):13. PMID: 19295934.
      Citations:    Fields:    Translation:Humans
    48. Leung DH, Williams K, Fraley JK, Klish WJ. Age- and ethnic-specific elevation of ALT among obese children at risk for nonalcoholic steatohepatitis (NASH): implications for screening. Clin Pediatr (Phila). 2009 Jan; 48(1):50-7. PMID: 18832535.
      Citations: 6     Fields:    Translation:Humans
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