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CAROLINA JORGEZ

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Urology
DivisionUrology
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Reproductive Medicine
    DivisionCenter for Reproductive Medicine


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ren YA, Monkkonen T, Lewis MT, Bernard DJ, Christian HC, Jorgez CJ, Moore JA, Landua JD, Chin HM, Chen W, Singh S, Kim IS, Zhang XH, Xia Y, Phillips KJ, MacKay H, Waterland RA, Ljungberg MC, Saha PK, Hartig SM, Coll TF, Richards JS. S100a4-Cre-mediated deletion of Patched1 causes hypogonadotropic hypogonadism: role of pituitary hematopoietic cells in endocrine regulation. JCI Insight. 2019 Jul 02; 5. PMID: 31265437.
      View in: PubMed
    2. Gerber JA, Balasubramanian A, Jorgez CJ, Shukla MA, Jacob JS, Zhu H, Sheth KR, Mittal A, Tu DD, Koh CJ, Janzen N, Wang MH, Austin PF, Gonzales ET, Roth DR, Seth A. Do pediatricians routinely perform genitourinary examinations during well-child visits? A review from a large tertiary pediatric hospital. J Pediatr Urol. 2019 May 23. PMID: 31229415.
      View in: PubMed
    3. White JT, Kovar E, Chambers TM, Sheth KR, Peckham-Gregory EC, O'Neill M, Langlois PH, Jorgez CJ, Lupo PJ, Seth A. Hypospadias Risk from Maternal Residential Exposure to Heavy Metal Hazardous Air Pollutants. Int J Environ Res Public Health. 2019 03 15; 16(6). PMID: 30875870.
      View in: PubMed
    4. Sheth KR, Kovar E, White JT, Chambers TM, Peckham-Gregory EC, O'Neill M, Langlois PH, Seth A, Scheurer ME, Lupo PJ, Jorgez CJ. Hypospadias risk is increased with maternal residential exposure to hormonally active hazardous air pollutants. Birth Defects Res. 2019 Apr 15; 111(7):345-352. PMID: 30694020.
      View in: PubMed
    5. Sheth KR, White JT, Perez-Orozco AF, Debolske ND, Hyde CR, Geistkemper C, Roth DR, Austin PF, Gonzales ET, Janzen NK, Tu DD, Mittal AG, Koh CJ, Ryan SL, Jorgez C, Seth A. Evaluating Natural History and Follow Up Strategies for Non-obstructive Urolithiasis in Pediatric Population. Front Pediatr. 2018; 6:353. PMID: 30505832.
      View in: PubMed
    6. Sheriff FR, Lopez A, Lupo PJ, Seth A, Jorgez C, Agopian AJ. Maternal hypertension and hypospadias in offspring: A systematic review and meta-analysis. Birth Defects Res. 2019 01 01; 111(1):9-15. PMID: 30411533.
      View in: PubMed
    7. White JT, Sheth KR, Bilgutay AN, Roth DR, Austin PF, Gonzales ET, Janzen NK, Tu DD, Mittal AG, Koh CJ, Ryan SL, Jorgez C, Seth A. Corrigendum: Vesicoamniotic Shunting Improves Outcomes in a Subset of Prune Belly Syndrome Patients at a Single Tertiary Center. Front Pediatr. 2018; 6:229. PMID: 30140665.
      View in: PubMed
    8. Sheth KR, White JT, Janzen N, Koh CJ, Austin PF, Roth DR, Tu DD, Mittal A, Wang MH, Gonzales ET, Jorgez C, Seth A. Evaluating Outcomes of Differential Surgical Management of Nonfunctioning Upper Pole Renal Moieties in Duplex Collecting Systems. Urology. 2019 01; 123:198-203. PMID: 30031832.
      View in: PubMed
    9. White JT, Sheth KR, Bilgutay AN, Roth DR, Austin PF, Gonzales ET, Janzen NK, Tu DD, Mittal AG, Koh CJ, Ryan SL, Jorgez C, Seth A. Vesicoamniotic Shunting Improves Outcomes in a Subset of Prune Belly Syndrome Patients at a Single Tertiary Center. Front Pediatr. 2018; 6:180. PMID: 30018947.
      View in: PubMed
    10. Dietrich JE, Adeyemi O, Hakim J, Santos X, Bercaw-Pratt JL, Bournat JC, Chen CH, Jorgez CJ. Paratubal Cyst Size Correlates With Obesity and Dysregulation of the Wnt Signaling Pathway. J Pediatr Adolesc Gynecol. 2017 Oct; 30(5):571-577. PMID: 28456695.
      View in: PubMed
    11. Jorgez CJ, Wilken N, Addai JB, Newberg J, Vangapandu HV, Pastuszak AW, Mukherjee S, Rosenfeld JA, Lipshultz LI, Lamb DJ. Genomic and genetic variation in E2F transcription factor-1 in men with nonobstructive azoospermia. Fertil Steril. 2015 Jan; 103(1):44-52.e1. PMID: 25439843.
      View in: PubMed
    12. Jorgez CJ, Rosenfeld JA, Wilken NR, Vangapandu HV, Sahin A, Pham D, Carvalho CM, Bandholz A, Miller A, Weaver DD, Burton B, Babu D, Bamforth JS, Wilks T, Flynn DP, Roeder E, Patel A, Cheung SW, Lupski JR, Lamb DJ. Genitourinary defects associated with genomic deletions in 2p15 encompassing OTX1. PLoS One. 2014; 9(9):e107028. PMID: 25203062.
      View in: PubMed
    13. Jorgez CJ, Weedin JW, Sahin A, Tannour-Louet M, Han S, Bournat JC, Mielnik A, Cheung SW, Nangia A, Schlegel PN, Lipshultz LI, Lamb DJ. Y-chromosome microdeletions are not associated with SHOX haploinsufficiency. Hum Reprod. 2014 May; 29(5):1113-4. PMID: 24634249.
      View in: PubMed
    14. Jorgez CJ, Weedin JW, Sahin A, Tannour-Louet M, Han S, Bournat JC, Mielnik A, Cheung SW, Nangia AK, Schlegel PN, Lipshultz LI, Lamb DJ. Aberrations in pseudoautosomal regions (PARs) found in infertile men with Y-chromosome microdeletions. J Clin Endocrinol Metab. 2011 Apr; 96(4):E674-9. PMID: 21252244.
      View in: PubMed
    15. Hwang K, Yatsenko AN, Jorgez CJ, Mukherjee S, Nalam RL, Matzuk MM, Lamb DJ. Mendelian genetics of male infertility. Ann N Y Acad Sci. 2010 Dec; 1214:E1-E17. PMID: 21382200.
      View in: PubMed
    16. Jorgez CJ, Bischoff FZ. Improving enrichment of circulating fetal DNA for genetic testing: size fractionation followed by whole gene amplification. Fetal Diagn Ther. 2009; 25(3):314-9. PMID: 19776594.
      View in: PubMed
    17. Orozco AF, Jorgez CJ, Ramos-Perez WD, Popek EJ, Yu X, Kozinetz CA, Bischoff FZ, Lewis DE. Placental release of distinct DNA-associated micro-particles into maternal circulation: reflective of gestation time and preeclampsia. Placenta. 2009 Oct; 30(10):891-7. PMID: 19692120.
      View in: PubMed
    18. Shen JJ, Huang L, Li L, Jorgez C, Matzuk MM, Brown CW. Deficiency of growth differentiation factor 3 protects against diet-induced obesity by selectively acting on white adipose. Mol Endocrinol. 2009 Jan; 23(1):113-23. PMID: 19008465.
      View in: PubMed
    19. Jorgez CJ, Bischoff FZ. Stability of placental RNA using dried maternal blood spots. Reprod Biomed Online. 2008 Nov; 17(5):716-21. PMID: 18983758.
      View in: PubMed
    20. Orozco AF, Jorgez CJ, Horne C, Marquez-Do DA, Chapman MR, Rodgers JR, Bischoff FZ, Lewis DE. Membrane protected apoptotic trophoblast microparticles contain nucleic acids: relevance to preeclampsia. Am J Pathol. 2008 Dec; 173(6):1595-608. PMID: 18974299.
      View in: PubMed
    21. Li Q, Pangas SA, Jorgez CJ, Graff JM, Weinstein M, Matzuk MM. Redundant roles of SMAD2 and SMAD3 in ovarian granulosa cells in vivo. Mol Cell Biol. 2008 Dec; 28(23):7001-11. PMID: 18809571.
      View in: PubMed
    22. Pangas SA, Jorgez CJ, Tran M, Agno J, Li X, Brown CW, Kumar TR, Matzuk MM. Intraovarian activins are required for female fertility. Mol Endocrinol. 2007 Oct; 21(10):2458-71. PMID: 17609433.
      View in: PubMed
    23. Jorgez CJ, Dang DD, Wapner R, Farina A, Simpson JL, Bischoff FZ. Elevated levels of total (maternal and fetal) beta-globin DNA in maternal blood from first trimester pregnancies with trisomy 21. Hum Reprod. 2007 Aug; 22(8):2267-72. PMID: 17584747.
      View in: PubMed
    24. Jorgez CJ, Simpson JL, Bischoff FZ. Recovery and amplification of placental RNA from dried maternal blood spots: utility for non-invasive prenatal diagnosis. Reprod Biomed Online. 2006 Oct; 13(4):558-61. PMID: 17007679.
      View in: PubMed
    25. Jorgez CJ, Dang DD, Simpson JL, Lewis DE, Bischoff FZ. Quantity versus quality: optimal methods for cell-free DNA isolation from plasma of pregnant women. Genet Med. 2006 Oct; 8(10):615-9. PMID: 17079877.
      View in: PubMed
    26. Jorgez CJ, De Mayo FJ, Matzuk MM. Inhibin alpha-iCre mice: Cre deleter lines for the gonads, pituitary, and adrenal. Genesis. 2006 Apr; 44(4):183-8. PMID: 16604527.
      View in: PubMed
    27. Jorgez CJ, Lin YN, Matzuk MM. Genetic manipulations to study reproduction. Mol Cell Endocrinol. 2005 Apr 29; 234(1-2):127-35. PMID: 15836961.
      View in: PubMed
    28. Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I. Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell. 2004 Nov; 7(5):719-30. PMID: 15525533.
      View in: PubMed
    29. Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Wankell M, Werner S, Thesleff I. Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn. 2004 Sep; 231(1):98-108. PMID: 15305290.
      View in: PubMed
    30. Yao HH, Matzuk MM, Jorgez CJ, Menke DB, Page DC, Swain A, Capel B. Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn. 2004 Jun; 230(2):210-5. PMID: 15162500.
      View in: PubMed
    31. Tutuncu L, Stein P, Ord TS, Jorgez CJ, Williams CJ. Calreticulin on the mouse egg surface mediates transmembrane signaling linked to cell cycle resumption. Dev Biol. 2004 Jun 01; 270(1):246-60. PMID: 15136153.
      View in: PubMed
    32. Pangas SA, Jorgez CJ, Matzuk MM. Growth differentiation factor 9 regulates expression of the bone morphogenetic protein antagonist gremlin. J Biol Chem. 2004 Jul 30; 279(31):32281-6. PMID: 15133038.
      View in: PubMed
    33. Travis AJ, Tutuncu L, Jorgez CJ, Ord TS, Jones BH, Kopf GS, Williams CJ. Requirements for glucose beyond sperm capacitation during in vitro fertilization in the mouse. Biol Reprod. 2004 Jul; 71(1):139-45. PMID: 14985248.
      View in: PubMed
    34. Jorgez CJ, Klysik M, Jamin SP, Behringer RR, Matzuk MM. Granulosa cell-specific inactivation of follistatin causes female fertility defects. Mol Endocrinol. 2004 Apr; 18(4):953-67. PMID: 14701941.
      View in: PubMed
    35. Travis AJ, Jorgez CJ, Merdiushev T, Jones BH, Dess DM, Diaz-Cueto L, Storey BT, Kopf GS, Moss SB. Functional relationships between capacitation-dependent cell signaling and compartmentalized metabolic pathways in murine spermatozoa. J Biol Chem. 2001 Mar 09; 276(10):7630-6. PMID: 11115497.
      View in: PubMed
    36. Visconti PE, Galantino-Homer H, Ning X, Moore GD, Valenzuela JP, Jorgez CJ, Alvarez JG, Kopf GS. Cholesterol efflux-mediated signal transduction in mammalian sperm. beta-cyclodextrins initiate transmembrane signaling leading to an increase in protein tyrosine phosphorylation and capacitation. J Biol Chem. 1999 Jan 29; 274(5):3235-42. PMID: 9915865.
      View in: PubMed
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