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BERT W O'MALLEY

TitleChair
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
DivisionMolecular & Cellular Biology
AddressOne Baylor Plaza
Houston TX 77030
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    Other Positions
    TitleDistinguished Service Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Endocrinology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience
    DivisionNeuroscience

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Obstetrics & Gynecology
    DivisionObstetrics and Gynecology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Gates LA, Shi J, Rohira AD, Feng Q, Zhu B, Bedford MT, Sagum CA, Jung SY, Qin J, Tsai MJ, Tsai SY, Li W, Foulds CE, O'Malley BW. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017 Jul 17. PMID: 28717009.
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    2. Bur AM, Gomez ED, Newman JG, Weinstein GS, O'Malley BW, Rassekh CH, Kuchenbecker KJ. Evaluation of high-fidelity simulation as a training tool in transoral robotic surgery. Laryngoscope. 2017 Jun 28. PMID: 28657696.
      View in: PubMed
    3. Banerjee S, Tian T, Wei Z, Peck KN, Shih N, Chalian AA, O'Malley BW, Weinstein GS, Feldman MD, Alwine J, Robertson ES. Microbial Signatures Associated with Oropharyngeal and Oral Squamous Cell Carcinomas. Sci Rep. 2017 Jun 22; 7(1):4036. PMID: 28642609.
      View in: PubMed
    4. Zhang Z, Nikolai BC, Gates LA, Jung SY, Siwak EB, He B, Rice AP, O'Malley BW, Feng Q. Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency. Nucleic Acids Res. 2017 Jun 20. PMID: 28637181.
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    5. Rohira AD, Yan F, Wang L, Wang J, Zhou S, Lu A, Yu Y, Xu J, Lonard DM, O'Malley BW. Targeting SRC coactivators blocks the tumor-initiating capacity of cancer stem-like cells. Cancer Res. 2017 Jun 13. PMID: 28611048.
      View in: PubMed
    6. Geng C, Kaochar S, Li M, Rajapakshe K, Fiskus W, Dong J, Foley C, Dong B, Zhang L, Kwon OJ, Shah SS, Bolaki M, Xin L, Ittmann M, O'Malley BW, Coarfa C, Mitsiades N. SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein. Oncogene. 2017 Apr 17. PMID: 28414305.
      View in: PubMed
    7. Xu Y, O'Malley BW, Elmquist JK. Brain nuclear receptors and body weight regulation. J Clin Invest. 2017 Feb 20. PMID: 28218618.
      View in: PubMed
    8. Xu Q, Shanti RM, Zhang Q, Cannady SB, O'Malley BW, Le AD. A Gingiva-Derived Mesenchymal Stem Cell-Laden Porcine Small Intestinal Submucosa Extracellular Matrix Construct Promotes Myomucosal Regeneration of the Tongue. Tissue Eng Part A. 2017 Jan 04. PMID: 27923325.
      View in: PubMed
    9. Hatten KM, O'Malley BW, Bur AM, Patel MR, Rassekh CH, Newman JG, Cannady SB, Chalian AA, Hodnett BL, Lin A, Lukens JN, Cohen RB, Bauml JM, Montone KT, Livolsi VA, Weinstein GS. Transoral Robotic Surgery-Assisted Endoscopy With Primary Site Detection and Treatment in Occult Mucosal Primaries. JAMA Otolaryngol Head Neck Surg. 2016 Dec 08. PMID: 27930761.
      View in: PubMed
    10. Ojerholm E, Lukens JN, Ahn PH, Geiger G, Swisher-McClure S, Newman J, Chalian A, Weinstein G, O'Malley BW, Cohen R, Lin A. Benefits of omitting primary site radiation therapy after transoral robotic surgery: Only time will tell. Pract Radiat Oncol. 2016 Nov 04. PMID: 28094210.
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    11. O'Malley BW. Origins of the Field of Molecular Endocrinology: A Personal Perspective. Mol Endocrinol. 2016 Oct; 30(10):1015-1018. PMID: 27690769.
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    12. Lonard DM, O'Malley BW. Molecular Pathways: Targeting Steroid Receptor Coactivators in Cancer. Clin Cancer Res. 2016 Sep 21. PMID: 27654711.
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    13. Ahn PH, Mitra N, Alonso-Basanta M, Palmer JN, Adappa ND, O'Malley BW, Rassekh C, Chalian A, Cohen RB, Lin A. Risk of lymph node metastasis and recommendations for elective nodal treatment in squamous cell carcinoma of the nasal cavity and maxillary sinus: a SEER analysis. Acta Oncol. 2016 Sep - Oct; 55(9-10):1107-1114. PMID: 27685421.
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    14. Fleet T, Stashi E, Zhu B, Rajapakshe K, Marcelo KL, Kettner NM, Gorman BK, Coarfa C, Fu L, O'Malley BW, York B. Genetic and Environmental Models of Circadian Disruption Link SRC-2 Function to Hepatic Pathology. J Biol Rhythms. 2016 Jul 17. PMID: 27432117.
      View in: PubMed
    15. Brody RM, Pandey NC, Bur AM, O'Malley BW, Rassekh CH, Weinstein GS, Chalian AA, Newman JG, Cannady SB. Anterior lateral thigh osteomyocutaneous free flap reconstruction in the head and neck: The anterolateral thigh osteomyocutaneous femur bone flap. Head Neck. 2016 Dec; 38(12):1788-1793. PMID: 27310816.
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    16. Wang Q, Trevino LS, Wong RL, Medvedovic M, Chen J, Ho SM, Shen J, Foulds CE, Coarfa C, O'Malley BW, Shilatifard A, Walker CL. Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk. Mol Endocrinol. 2016 Aug; 30(8):856-71. PMID: 27219490; PMCID: PMC4965842 [Available on 08/01/17].
    17. Khalili S, Worrall DM, Brooks S, Morris SM, Farquhar D, Newman JG, Learned KO, Ahn PH, Craig J, Kennedy DW, O'Malley BW, Palmer JN, Adappa ND. Endoscopy versus imaging: Analysis of surveillance methods in sinonasal malignancy. Head Neck. 2016 Aug; 38(8):1229-33. PMID: 27142811.
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    18. Wang L, Lonard DM, O'Malley BW. The Role of Steroid Receptor Coactivators in Hormone Dependent Cancers and Their Potential as Therapeutic Targets. Horm Cancer. 2016 Aug; 7(4):229-35. PMID: 27125199; PMCID: PMC4930410 [Available on 08/01/17].
    19. Song X, Chen J, Zhao M, Zhang C, Yu Y, Lonard DM, Chow DC, Palzkill T, Xu J, O'Malley BW, Wang J. Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3. Proc Natl Acad Sci U S A. 2016 May 3; 113(18):4970-5. PMID: 27084884.
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    20. Rassekh CH, O'Malley BW, Bewley AF, Montone KT, Livolsi VA, Weinstein GS. Feasibility and relevance of level I substation node counts in oropharyngeal carcinoma. Head Neck. 2016 Aug; 38(8):1194-200. PMID: 27028011.
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    21. Farquhar D, Kim L, Worrall D, Chiu A, Lee JY, Khalili S, Grady S, O'Malley BW, Kennedy DW, Newman JG, Palmer JN, Adappa ND. Propensity score analysis of endoscopic and open approaches to malignant paranasal and anterior skull base tumor outcomes. Laryngoscope. 2016 Aug; 126(8):1724-9. PMID: 26972568.
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    22. Xu J, Zhou L, Ji L, Chen F, Fortmann K, Zhang K, Liu Q, Li K, Wang W, Wang H, Xie W, Wang Q, Liu J, Zheng B, Zhang P, Huang S, Shi T, Zhang B, Dang Y, Chen J, O'Malley BW, Moses RE, Wang P, Li L, Xiao J, Hoffmann A, Li X. The REG?-proteasome forms a regulatory circuit with I?B? and NF?B in experimental colitis. Nat Commun. 2016; 7:10761. PMID: 26899380; PMCID: PMC4764899.
    23. Ahn PH, Quon H, O'Malley BW, Weinstein G, Chalian A, Malloy K, Atkins JH, Sollecito T, Greenberg M, McNulty S, Lin A, Zhu TC, Finlay JC, Cengel K, Livolsi V, Feldman M, Mick R, Busch TM. Toxicities and early outcomes in a phase 1 trial of photodynamic therapy for premalignant and early stage head and neck tumors. Oral Oncol. 2016 Apr; 55:37-42. PMID: 26865261.
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    24. Nikolai BC, Lanz RB, York B, Dasgupta S, Mitsiades N, Creighton CJ, Tsimelzon A, Hilsenbeck SG, Lonard DM, Smith CL, O'Malley BW. HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes. Cancer Res. 2016 Feb 1. PMID: 26833126.
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    25. Li L, Chao T, Brant J, O'Malley B, Tsourkas A, Li D. Advances in Nano-based inner ear delivery systems for the treatment of sensorineural hearing loss. Adv Drug Deliv Rev. 2016 Jan 12. PMID: 26796230.
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    26. Foulds CE, Panigrahi AK, Coarfa C, Lanz RB, O'Malley BW. Long Noncoding RNAs as Targets and Regulators of Nuclear Receptors. Curr Top Microbiol Immunol. 2016; 394:143-76. PMID: 26362934.
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    27. Zhang Z, Brown JC, O'Malley BW, Troxel AB, Bauml JM, Rubnitz KR, Grosso CM, Weinstein GS, Schmitz KH. Post-treatment weight change in oral cavity and oropharyngeal squamous cell carcinoma. Support Care Cancer. 2016 May; 24(5):2333-40. PMID: 26619995.
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    28. Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Correction: Perturbing the Cellular Levels of Steroid Receptor Coactivator-2 Impairs Murine Endometrial Function. PLoS One. 2015; 10(11):e0143652. PMID: 26580555; PMCID: PMC4651323.
    29. Ahn PH, Mitra N, Alonso-Basanta M, Adappa ND, Palmer JN, O'Malley BW, Rassekh CH, Chalian A, Cohen RB, Lin A. Nodal metastasis and elective nodal level treatment in sinonasal small-cell and sinonasal undifferentiated carcinoma: a surveillance, epidemiology and end results analysis. Br J Radiol. 2016 Feb; 89(1058):20150488. PMID: 26559439.
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    30. Han SJ, Jung SY, Wu SP, Hawkins SM, Park MJ, Kyo S, Qin J, Lydon JP, Tsai SY, Tsai MJ, DeMayo FJ, O'Malley BW. Estrogen Receptor ß Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 2015 Nov 5; 163(4):960-74. PMID: 26544941.
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    31. Han SJ, Begum K, Foulds CE, Hamilton RA, Bailey S, Malovannaya A, Chan D, Qin J, O'Malley BW. The Dual ERa Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety. Mol Pharmacol. 2015 Oct 20. PMID: 26487511.
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    32. Fleet T, Zhang B, Lin F, Zhu B, Dasgupta S, Stashi E, Tackett B, Thevananther S, Rajapakshe KI, Gonzales N, Dean A, Mao J, Timchenko N, Malovannaya A, Qin J, Coarfa C, DeMayo F, Dacso CC, Foulds CE, O'Malley BW, York B. SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis. Proc Natl Acad Sci U S A. 2015 Nov 3; 112(44):E6068-77. PMID: 26487680.
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    33. Song X, Zhang C, Zhao M, Chen H, Liu X, Chen J, Lonard DM, Qin L, Xu J, Wang X, Li F, O'Malley BW, Wang J. Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug. PLoS One. 2015; 10(10):e0140011. PMID: 26431029.
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    34. Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BW. Correction: Acceleration of the Glycolytic Flux by Steroid Receptor Coactivator-2 Is Essential for Endometrial Decidualization. PLoS Genet. 2015 Sep; 11(9):e1005515. PMID: 26418340.
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    35. Lv Y, Meng B, Dong H, Jing T, Wu N, Yang Y, Huang L, Moses RE, O'Malley BW, Mei B, Li X. Upregulation of GSK3? Contributes to Brain Disorders in Elderly REG?-knockout Mice. Neuropsychopharmacology. 2016 Apr; 41(5):1340-9. PMID: 26370326; PMCID: PMC4793118 [Available on 04/01/17].
    36. Coarfa C, Fiskus W, Eedunuri VK, Rajapakshe K, Foley C, Chew SA, Shah SS, Geng C, Shou J, Mohamed JS, O'Malley BW, Mitsiades N. Comprehensive proteomic profiling identifies the androgen receptor axis and other signaling pathways as targets of microRNAs suppressed in metastatic prostate cancer. Oncogene. 2016 May 5; 35(18):2345-56. PMID: 26364608.
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    37. Tanaka N, Lajud SA, Ramsey A, Szymanowski AR, Ruffner R, O'Malley BW, Li D. Application of infrared-based molecular imaging to a mouse model with head and neck cancer. Head Neck. 2016 Apr; 38 Suppl 1:E1351-7. PMID: 26348614.
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    38. Jin F, Bhowmik SK, Putluri V, Gu F, Gohlke J, Von Rundstedt FC, Dasgupta S, Krishnapuram R, O'Malley BW, Sreekumar A, Putluri N. A Novel [(15)N] Glutamine Flux using LC-MS/MS-SRM for Determination of Nucleosides and Nucleobases. J Anal Bioanal Tech. 2015 Oct; 6(5). PMID: 27158554.
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    39. Szwarc MM, Lydon JP, O'Malley BW. Reprint of "Steroid receptor coactivators as therapeutic targets in the female reproductive system". J Steroid Biochem Mol Biol. 2015 Sep; 153:144-50. PMID: 26291832.
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    40. Wang L, Yu Y, Chow DC, Yan F, Hsu CC, Stossi F, Mancini MA, Palzkill T, Liao L, Zhou S, Xu J, Lonard DM, O'Malley BW. Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10; 28(2):240-52. PMID: 26267537.
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    41. Thaler ER, Rassekh CH, Lee JM, Weinstein GS, O'Malley BW. Outcomes for multilevel surgery for sleep apnea: Obstructive sleep apnea, transoral robotic surgery, and uvulopalatopharyngoplasty. Laryngoscope. 2016 Jan; 126(1):266-9. PMID: 26153069.
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    42. Szwarc MM, Lydon JP, O'Malley BW. Steroid receptor coactivators as therapeutic targets in the female reproductive system. J Steroid Biochem Mol Biol. 2015 Nov; 154:32-8. PMID: 26151740.
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    43. Gallagher-Colombo SM, Quon H, Malloy KM, Ahn PH, Cengel KA, Simone CB, Chalian AA, O'Malley BW, Weinstein GS, Zhu TC, Putt ME, Finlay JC, Busch TM. Measuring the Physiologic Properties of Oral Lesions Receiving Fractionated Photodynamic Therapy. Photochem Photobiol. 2015 Sep-Oct; 91(5):1210-8. PMID: 26037487.
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    44. Grover S, Swisher-McClure S, Mitra N, Li J, Cohen RB, Ahn PH, Lukens JN, Chalian AA, Weinstein GS, O'Malley BW, Lin A. Total Laryngectomy Versus Larynx Preservation for T4a Larynx Cancer: Patterns of Care and Survival Outcomes. Int J Radiat Oncol Biol Phys. 2015 Jul 1; 92(3):594-601. PMID: 26068492.
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    45. Gao L, Rabbitt EH, Condon JC, Renthal NE, Johnston JM, Mitsche MA, Chambon P, Xu J, O'Malley BW, Mendelson CR. Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest. 2015 Jul 1; 125(7):2808-24. PMID: 26098214.
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    46. Eedunuri VK, Rajapakshe K, Fiskus W, Geng C, Chew SA, Foley C, Shah SS, Shou J, Mohamed JS, Coarfa C, O'Malley BW, Mitsiades N. miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation. Mol Endocrinol. 2015 Aug; 29(8):1170-83. PMID: 26066330.
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    47. Kovatch KJ, Purkey MT, Martinez-Lage M, Gausas RE, Loevner LA, Grady MS, O'Malley BW, Rassekh CH. Management of an expansile orbital mass: Plexiform neurofibroma decompression by orbitozygomatic approach. Laryngoscope. 2015 Nov; 125(11):2457-60. PMID: 25960281.
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    48. Kaczmar JM, Tan KS, Heitjan DF, Lin A, Ahn PH, Newman JG, Rassekh CH, Chalian AA, O'Malley BW, Cohen RB, Weinstein GS. HPV-related oropharyngeal cancer: Risk factors for treatment failure in patients managed with primary transoral robotic surgery. Head Neck. 2016 Jan; 38(1):59-65. PMID: 25197014.
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    49. Kang YK, Putluri N, Maity S, Tsimelzon A, Ilkayeva O, Mo Q, Lonard D, Michailidis G, Sreekumar A, Newgard CB, Wang M, Tsai SY, Tsai MJ, O'Malley BW. CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-?-Gabpa and stress-induced adaptive responses via NF-?B-cMYC. PLoS Genet. 2015 Apr; 11(4):e1005116. PMID: 25830341; PMCID: PMC4382186.
    50. Yi P, Wang Z, Feng Q, Pintilie GD, Foulds CE, Lanz RB, Ludtke SJ, Schmid MF, Chiu W, O'Malley BW. Structure of a biologically active estrogen receptor-coactivator complex on DNA. Mol Cell. 2015 Mar 19; 57(6):1047-58. PMID: 25728767; PMCID: PMC4369429.
    51. Dasgupta S, Putluri N, Long W, Zhang B, Wang J, Kaushik AK, Arnold JM, Bhowmik SK, Stashi E, Brennan CA, Rajapakshe K, Coarfa C, Mitsiades N, Ittmann MM, Chinnaiyan AM, Sreekumar A, O'Malley BW. Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis. J Clin Invest. 2015 Mar 2; 125(3):1174-88. PMID: 25664849; PMCID: PMC4362260.
    52. Lajud SA, Nagda DA, Qiao P, Tanaka N, Civantos A, Gu R, Cheng Z, Tsourkas A, O'Malley BW, Li D. A novel chitosan-hydrogel-based nanoparticle delivery system for local inner ear application. Otol Neurotol. 2015 Feb; 36(2):341-7. PMID: 25587675; PMCID: PMC4365436.
    53. Sperry SM, O'Malley BW, Weinstein GS. The University of Pennsylvania curriculum for training otorhinolaryngology residents in transoral robotic surgery. ORL J Otorhinolaryngol Relat Spec. 2014; 76(6):342-52. PMID: 25591714.
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    54. Omolehinwa TT, Musbah T, Desai B, O'Malley BW, Stoopler ET. Neuralgia associated with transcutaneous electrical nerve stimulation therapy in a patient initially diagnosed with temporomandibular disorder. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Mar; 119(3):e101-4. PMID: 25660829.
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    55. McKenna NJ, Evans RM, O'Malley BW. Nuclear Receptor Signaling: a home for nuclear receptor and coregulator signaling research. Nucl Recept Signal. 2014; 12:e006. PMID: 25614732; PMCID: PMC4303009.
    56. He B, Lanz RB, Fiskus W, Geng C, Yi P, Hartig SM, Rajapakshe K, Shou J, Wei L, Shah SS, Foley C, Chew SA, Eedunuri VK, Bedoya DJ, Feng Q, Minami T, Mitsiades CS, Frolov A, Weigel NL, Hilsenbeck SG, Rosen DG, Palzkill T, Ittmann MM, Song Y, Coarfa C, O'Malley BW, Mitsiades N. GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):18261-6. PMID: 25489091; PMCID: PMC4280633.
    57. Weinstein GS, O'Malley BW, Rinaldo A, Silver CE, Werner JA, Ferlito A. Understanding contraindications for transoral robotic surgery (TORS) for oropharyngeal cancer. Eur Arch Otorhinolaryngol. 2015 Jul; 272(7):1551-2. PMID: 25327689.
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    58. Lajud SA, Nagda DA, Yamashita T, Zheng J, Tanaka N, Abuzeid WM, Civantos A, Bezpalko O, O'Malley BW, Li D. Dual disruption of DNA repair and telomere maintenance for the treatment of head and neck cancer. Clin Cancer Res. 2014 Dec 15; 20(24):6465-78. PMID: 25324139.
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    59. Gustafsson JA, Katzenellenbogen B, Jameson JL, Roth J, Melmed S, McDonnell D, Wartofsky L, Crowley WF, Griz LH, Becker C, Moore DD, Drucker D, Singh N, O'Malley B. Endocrine Society 2014 Laureate Awards. Horm Cancer. 2014 Oct; 5(5):339-55. PMID: 25091407.
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    60. Wang W, Bian K, Vallabhaneni S, Zhang B, Wu RC, O'Malley BW, Long W. ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expression. J Cell Physiol. 2014 Oct; 229(10):1529-37. PMID: 24585635; PMCID: PMC4078721.
    61. Rechoum Y, Rovito D, Iacopetta D, Barone I, Andò S, Weigel NL, O'Malley BW, Brown PH, Fuqua SA. AR collaborates with ER? in aromatase inhibitor-resistant breast cancer. Breast Cancer Res Treat. 2014 Oct; 147(3):473-85. PMID: 25178514; PMCID: PMC4337991.
    62. Tannour-Louet M, York B, Tang K, Stashi E, Bouguerra H, Zhou S, Yu H, Wong LJ, Stevens RD, Xu J, Newgard CB, O'Malley BW, Louet JF. Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis. Mol Endocrinol. 2014 Oct; 28(10):1707-18. PMID: 25148457; PMCID: PMC4179626.
    63. Dasgupta S, O'Malley BW. Transcriptional coregulators: emerging roles of SRC family of coactivators in disease pathology. J Mol Endocrinol. 2014 Oct; 53(2):R47-59. PMID: 25024406; PMCID: PMC4152414.
    64. Hays T, Ma'ayan A, Clark NR, Tan CM, Teixeira A, Teixeira A, Choi JW, Burdis N, Jung SY, Bajaj AO, O'Malley BW, He JC, Hyink DP, Klotman PE. Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte. PLoS One. 2014; 9(6):e100660. PMID: 24949636; PMCID: PMC4065073.
    65. Stashi E, York B, O'Malley BW. Steroid receptor coactivators: servants and masters for control of systems metabolism. Trends Endocrinol Metab. 2014 Jul; 25(7):337-47. PMID: 24953190; PMCID: PMC4108168.
    66. Feng Q, O'Malley BW. Nuclear receptor modulation--role of coregulators in selective estrogen receptor modulator (SERM) actions. Steroids. 2014 Nov; 90:39-43. PMID: 24945111; PMCID: PMC4192004.
    67. Lukens JN, Lin A, Gamerman V, Mitra N, Grover S, McMenamin EM, Weinstein GS, O'Malley BW, Cohen RB, Orisamolu A, Ahn PH, Quon H. Late consequential surgical bed soft tissue necrosis in advanced oropharyngeal squamous cell carcinomas treated with transoral robotic surgery and postoperative radiation therapy. Int J Radiat Oncol Biol Phys. 2014 Aug 1; 89(5):981-8. PMID: 24928257.
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    68. Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function. PLoS One. 2014; 9(6):e98664. PMID: 24905738; PMCID: PMC4048228.
    69. Bäck LJ, Mäkitie AA, O'Malley BW, Owen RP, Rinaldo A, Silver CE, Ferlito A. When is radiofrequency ablation not indicated in head and neck squamous cell carcinoma management? Eur Arch Otorhinolaryngol. 2015 May; 272(5):1045-6. PMID: 24880470.
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    70. Feng Q, Zhang Z, Shea MJ, Creighton CJ, Coarfa C, Hilsenbeck SG, Lanz R, He B, Wang L, Fu X, Nardone A, Song Y, Bradner J, Mitsiades N, Mitsiades CS, Osborne CK, Schiff R, O'Malley BW. An epigenomic approach to therapy for tamoxifen-resistant breast cancer. Cell Res. 2014 Jul; 24(7):809-19. PMID: 24874954; PMCID: PMC4085766.
    71. Reineke EL, Benham A, Soibam B, Stashi E, Taegtmeyer H, Entman ML, Schwartz RJ, O'Malley BW. Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function. J Biol Chem. 2014 Jun 20; 289(25):17721-31. PMID: 24811170; PMCID: PMC4067206.
    72. Putluri N, Maity S, Kommagani R, Kommangani R, Creighton CJ, Putluri V, Chen F, Nanda S, Bhowmik SK, Terunuma A, Dorsey T, Nardone A, Fu X, Shaw C, Sarkar TR, Schiff R, Lydon JP, O'Malley BW, Ambs S, Das GM, Michailidis G, Sreekumar A. Pathway-centric integrative analysis identifies RRM2 as a prognostic marker in breast cancer associated with poor survival and tamoxifen resistance. Neoplasia. 2014 May; 16(5):390-402. PMID: 25016594; PMCID: PMC4198742.
    73. Yan F, Yu Y, Chow DC, Palzkill T, Madoux F, Hodder P, Chase P, Griffin PR, O'Malley BW, Lonard DM. Identification of verrucarin a as a potent and selective steroid receptor coactivator-3 small molecule inhibitor. PLoS One. 2014; 9(4):e95243. PMID: 24743578; PMCID: PMC3990629.
    74. Kommagani R, Szwarc MM, Kovanci E, Creighton CJ, O'Malley BW, Demayo FJ, Lydon JP. A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells. Biol Reprod. 2014 Apr; 90(4):75. PMID: 24571987; PMCID: PMC4076383.
    75. Han SJ, O'Malley BW. The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis. Hum Reprod Update. 2014 Jul-Aug; 20(4):467-84. PMID: 24634322; PMCID: PMC4063700.
    76. Zheng J, Nagda DA, Lajud SA, Kumar S, Mouchli A, Bezpalko O, O'Malley BW, Li D. Biliverdin's regulation of reactive oxygen species signalling leads to potent inhibition of proliferative and angiogenic pathways in head and neck cancer. Br J Cancer. 2014 Apr 15; 110(8):2116-22. PMID: 24569474; PMCID: PMC3992514.
    77. Kang YK, Jung SY, Qin J, Li C, Tsai SY, Tsai MJ, O'Malley BW. E2/Estrogen receptor/sjogren syndrome-associated autoantigen relieves coactivator activator-induced G1/S arrest to promote breast tumorigenicity. Mol Cell Biol. 2014 May; 34(9):1670-81. PMID: 24567374; PMCID: PMC3993604.
    78. Stashi E, Lanz RB, Mao J, Michailidis G, Zhu B, Kettner NM, Putluri N, Reineke EL, Reineke LC, Dasgupta S, Dean A, Stevenson CR, Sivasubramanian N, Sreekumar A, Demayo F, York B, Fu L, O'Malley BW. SRC-2 is an essential coactivator for orchestrating metabolism and circadian rhythm. Cell Rep. 2014 Feb 27; 6(4):633-45. PMID: 24529706; PMCID: PMC4096300.
    79. Motamed M, Rajapakshe KI, Hartig SM, Coarfa C, Moses RE, Lonard DM, O'Malley BW. Steroid receptor coactivator 1 is an integrator of glucose and NAD+/NADH homeostasis. Mol Endocrinol. 2014 Mar; 28(3):395-405. PMID: 24438340; PMCID: PMC3938540.
    80. Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BW. Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet. 2013 Oct; 9(10):e1003900. PMID: 24204309; PMCID: PMC3812085.
    81. Savulescu D, Feng J, Ping YS, Mai O, Boehm U, He B, O'Malley BW, Melamed P. Gonadotropin-releasing hormone-regulated prohibitin mediates apoptosis of the gonadotrope cells. Mol Endocrinol. 2013 Nov; 27(11):1856-70. PMID: 24085822.
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    82. Owen RP, Lee JS, Silver CE, Bäck L, Beitler JJ, Rinaldo A, O'Malley BW, Haigentz M, Ferlito A. Radiofrequency ablation in advanced head and neck cancer. Eur Arch Otorhinolaryngol. 2014 Feb; 271(2):207-10. PMID: 24061569.
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    84. Dong S, Jia C, Zhang S, Fan G, Li Y, Shan P, Sun L, Xiao W, Li L, Zheng Y, Liu J, Wei H, Hu C, Zhang W, Chin YE, Zhai Q, Li Q, Liu J, Jia F, Mo Q, Edwards DP, Huang S, Chan L, O'Malley BW, Li X, Wang C. The REG? proteasome regulates hepatic lipid metabolism through inhibition of autophagy. Cell Metab. 2013 Sep 3; 18(3):380-91. PMID: 24011073; PMCID: PMC3813599.
    85. Stashi E, Wang L, Mani SK, York B, O'Malley BW. Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences. Mol Endocrinol. 2013 Oct; 27(10):1776-87. PMID: 23927929; PMCID: PMC3787127.
    86. Ramakrishnan VR, Lee JY, O'Malley BW, Palmer JN, Chiu AG. 18-FDG-PET in the initial staging of sinonasal malignancy. Laryngoscope. 2013 Dec; 123(12):2962-6. PMID: 23877974.
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    87. Foulds CE, Feng Q, Ding C, Bailey S, Hunsaker TL, Malovannaya A, Hamilton RA, Gates LA, Zhang Z, Li C, Chan D, Bajaj A, Callaway CG, Edwards DP, Lonard DM, Tsai SY, Tsai MJ, Qin J, O'Malley BW. Proteomic analysis of coregulators bound to ER? on DNA and nucleosomes reveals coregulator dynamics. Mol Cell. 2013 Jul 25; 51(2):185-99. PMID: 23850489; PMCID: PMC3900250.
    88. Swisher-McClure S, Mitra N, Lin A, Ahn P, Wan F, O'Malley B, Weinstein GS, Bekelman JE. Risk of fatal cerebrovascular accidents after external beam radiation therapy for early-stage glottic laryngeal cancer. Head Neck. 2014 May; 36(5):611-6. PMID: 23595858; PMCID: PMC3795979.
    89. Li L, Zhao D, Wei H, Yao L, Dang Y, Amjad A, Xu J, Liu J, Guo L, Li D, Li Z, Zuo D, Zhang Y, Liu J, Huang S, Jia C, Wang L, Wang Y, Xie Y, Luo J, Zhang B, Luo H, Donehower LA, Moses RE, Xiao J, O'Malley BW, Li X. REG? deficiency promotes premature aging via the casein kinase 1 pathway. Proc Natl Acad Sci U S A. 2013 Jul 2; 110(27):11005-10. PMID: 23766372; PMCID: PMC3703992.
    90. Bhat-Nakshatri P, Song EK, Collins NR, Uversky VN, Dunker AK, O'Malley BW, Geistlinger TR, Carroll JS, Brown M, Nakshatri H. Interplay between estrogen receptor and AKT in estradiol-induced alternative splicing. BMC Med Genomics. 2013; 6:21. PMID: 23758675; PMCID: PMC3687557.
    91. Stoopler ET, Sia YW, Chalian AA, O'Malley BW, Alawi F. A rare presentation of multiple primary squamous cell carcinoma of the tongue in a patient with recurrent hepatitis C infection. Spec Care Dentist. 2014 Mar-Apr; 34(2):96-9. PMID: 24588494.
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    92. Geng C, He B, Xu L, Barbieri CE, Eedunuri VK, Chew SA, Zimmermann M, Bond R, Shou J, Li C, Blattner M, Lonard DM, Demichelis F, Coarfa C, Rubin MA, Zhou P, O'Malley BW, Mitsiades N. Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6997-7002. PMID: 23559371; PMCID: PMC3637757.
    93. Redfern AD, Colley SM, Beveridge DJ, Ikeda N, Epis MR, Li X, Foulds CE, Stuart LM, Barker A, Russell VJ, Ramsay K, Kobelke SJ, Li X, Hatchell EC, Payne C, Giles KM, Messineo A, Gatignol A, Lanz RB, O'Malley BW, Leedman PJ. RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6536-41. PMID: 23550157; PMCID: PMC3631673.
    94. O'Malley BW, Khan S. Elwood V. Jensen (1920-2012): father of the nuclear receptors. Proc Natl Acad Sci U S A. 2013 Mar 5; 110(10):3707-8. PMID: 23471960; PMCID: PMC3593867.
    95. Yi P, Xia W, Wu RC, Lonard DM, Hung MC, O'Malley BW. SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. Genes Dev. 2013 Feb 1; 27(3):274-87. PMID: 23388826; PMCID: PMC3576513.
    96. York B, Sagen JV, Tsimelzon A, Louet JF, Chopra AR, Reineke EL, Zhou S, Stevens RD, Wenner BR, Ilkayeva O, Bain JR, Xu J, Hilsenbeck SG, Newgard CB, O'Malley BW. Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family. Mol Endocrinol. 2013 Feb; 27(2):366-80. PMID: 23315938; PMCID: PMC3683811.
    97. Stewart M, Chandra R, Chiu A, Hanna E, Kennedy D, Kraus D, Gleeson M, Levine P, Niparko J, O'Malley B, Rosenfeld R, Ruben R, Sataloff R, Smith R, Weber P. The value of resident presentations at scientific meetings. Otolaryngol Head Neck Surg. 2013 Jan; 148(1):5. PMID: 23243136.
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    98. Reineke EL, York B, Stashi E, Chen X, Tsimelzon A, Xu J, Newgard CB, Taffet GE, Taegtmeyer H, Entman ML, O'Malley BW. SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart. PLoS One. 2012; 7(12):e53395. PMID: 23300926; PMCID: PMC3534027.
    99. Sánchez-Quiles V, Segura V, Bigaud E, He B, O'Malley BW, Santamaría E, Prieto J, Corrales FJ. Prohibitin-1 deficiency promotes inflammation and increases sensitivity to liver injury. J Proteomics. 2012 Oct 22; 75(18):5783-92. PMID: 22951295.
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    100. Liu SH, Rao DD, Nemunaitis J, Senzer N, Zhou G, Dawson D, Gingras MC, Wang Z, Gibbs R, Norman M, Templeton NS, Demayo FJ, O'Malley B, Sanchez R, Fisher WE, Brunicardi FC. PDX-1 is a therapeutic target for pancreatic cancer, insulinoma and islet neoplasia using a novel RNA interference platform. PLoS One. 2012; 7(8):e40452. PMID: 22905092; PMCID: PMC3414490.
    101. Han SJ, Hawkins SM, Begum K, Jung SY, Kovanci E, Qin J, Lydon JP, DeMayo FJ, O'Malley BW. A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med. 2012 Jul; 18(7):1102-11. PMID: 22660634; PMCID: PMC3541027.
    102. O'Malley BW, Malovannaya A, Qin J. Minireview: nuclear receptor and coregulator proteomics--2012 and beyond. Mol Endocrinol. 2012 Oct; 26(10):1646-50. PMID: 22745194; PMCID: PMC3458220.
    103. Lonard DM, O'Malley BW. Nuclear receptor coregulators: modulators of pathology and therapeutic targets. Nat Rev Endocrinol. 2012 Oct; 8(10):598-604. PMID: 22733267; PMCID: PMC3564250.
    104. Liu A, Margaill I, Zhang S, Labombarda F, Coqueran B, Delespierre B, Liere P, Marchand-Leroux C, O'Malley BW, Lydon JP, De Nicola AF, Sitruk-Ware R, Mattern C, Plotkine M, Schumacher M, Guennoun R. Progesterone receptors: a key for neuroprotection in experimental stroke. Endocrinology. 2012 Aug; 153(8):3747-57. PMID: 22635678; PMCID: PMC3979171.
    105. Moses RE, O'Malley BW. DNA transcription and repair: a confluence. J Biol Chem. 2012 Jul 6; 287(28):23266-70. PMID: 22605334; PMCID: PMC3390605.
    106. Park S, Yoon S, Zhao Y, Park SE, Liao L, Xu J, Lydon JP, DeMayo FJ, O'Malley BW, Bagchi MK, Katzenellenbogen BS. Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA. Endocrinology. 2012 Aug; 153(8):3982-94. PMID: 22585830; PMCID: PMC3404350.
    107. O'Donnell KA, Keng VW, York B, Reineke EL, Seo D, Fan D, Silverstein KA, Schrum CT, Xie WR, Mularoni L, Wheelan SJ, Torbenson MS, O'Malley BW, Largaespada DA, Boeke JD. A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):E1377-86. PMID: 22556267; PMCID: PMC3361419.
    108. York B, Reineke EL, Sagen JV, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, Stevens RD, Wenner BR, Ilkayeva O, Xu J, Newgard CB, O'Malley BW. Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. Cell Metab. 2012 May 2; 15(5):752-63. PMID: 22560224; PMCID: PMC3349072.
    109. Long W, Foulds CE, Qin J, Liu J, Ding C, Lonard DM, Solis LM, Wistuba II, Qin J, Tsai SY, Tsai MJ, O'Malley BW. ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion. J Clin Invest. 2012 May; 122(5):1869-80. PMID: 22505454; PMCID: PMC3336992.
    110. Wu MY, Fu J, Xu J, O'Malley BW, Wu RC. Steroid receptor coactivator 3 regulates autophagy in breast cancer cells through macrophage migration inhibitory factor. Cell Res. 2012 Jun; 22(6):1003-21. PMID: 22430150; PMCID: PMC3367527.
    111. Grosskopf CC, Kuperstein AS, O'Malley BW, Sollecito TP. Parapharyngeal space tumors: another consideration for otalgia and temporomandibular disorders. Head Neck. 2013 May; 35(5):E153-6. PMID: 22307772.
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    112. Hartmaier RJ, Richter AS, Gillihan RM, Sallit JZ, McGuire SE, Wang J, Lee AV, Osborne CK, O'Malley BW, Brown PH, Xu J, Skaar TC, Philips S, Rae JM, Azzouz F, Li L, Hayden J, Henry NL, Nguyen AT, Stearns V, Hayes DF, Flockhart DA, Oesterreich S. A SNP in steroid receptor coactivator-1 disrupts a GSK3? phosphorylation site and is associated with altered tamoxifen response in bone. Mol Endocrinol. 2012 Feb; 26(2):220-7. PMID: 22174377; PMCID: PMC3275159.
    113. Wang Y, Lonard DM, Yu Y, Chow DC, Palzkill TG, O'Malley BW. Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1. Mol Endocrinol. 2011 Dec; 25(12):2041-53. PMID: 22053001; PMCID: PMC3231837.
    114. Park S, Zhao Y, Yoon S, Xu J, Liao L, Lydon J, DeMayo F, O'Malley BW, Katzenellenbogen BS. Repressor of estrogen receptor activity (REA) is essential for mammary gland morphogenesis and functional activities: studies in conditional knockout mice. Endocrinology. 2011 Nov; 152(11):4336-49. PMID: 21862609; PMCID: PMC3199013.
    115. Johnson AB, O'Malley BW. Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapy. Mol Cell Endocrinol. 2012 Jan 30; 348(2):430-9. PMID: 21664237; PMCID: PMC3202666.
    116. Johnson AB, O'Malley BW. ERasing breast cancer resistance through the kinome. Nat Med. 2011 Jun; 17(6):660-1. PMID: 21647142.
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    117. Malovannaya A, Lanz RB, Jung SY, Bulynko Y, Le NT, Chan DW, Ding C, Shi Y, Yucer N, Krenciute G, Kim BJ, Li C, Chen R, Li W, Wang Y, O'Malley BW, Qin J. Analysis of the human endogenous coregulator complexome. Cell. 2011 May 27; 145(5):787-99. PMID: 21620140; PMCID: PMC3131083.
    118. Li C, Ao J, Fu J, Lee DF, Xu J, Lonard D, O'Malley BW. Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1. Oncogene. 2011 Oct 20; 30(42):4350-64. PMID: 21577200; PMCID: PMC3158261.
    119. Reddy SD, Rayala SK, Ohshiro K, Pakala SB, Kobori N, Dash P, Yun S, Qin J, O'Malley BW, Kumar R. Multiple coregulatory control of tyrosine hydroxylase gene transcription. Proc Natl Acad Sci U S A. 2011 Mar 8; 108(10):4200-5. PMID: 21368136; PMCID: PMC3054001.
    120. Chopra AR, Kommagani R, Saha P, Louet JF, Salazar C, Song J, Jeong J, Finegold M, Viollet B, DeMayo F, Chan L, Moore DD, O'Malley BW. Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption. Cell Metab. 2011 Jan 5; 13(1):35-43. PMID: 21195347; PMCID: PMC3072049.
    121. He B, Kim TH, Kommagani R, Feng Q, Lanz RB, Jeong JW, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology. 2011 Mar; 152(3):1047-56. PMID: 21209023; PMCID: PMC3040048.
    122. O'Malley BW. Cellular proteome, coregulators, endocrine system and the human brain: the Regulatory biology of humanism. Aging (Albany NY). 2011 Jan; 3(1):22-5. PMID: 21258135; PMCID: PMC3047135.
    123. Bulynko YA, O'Malley BW. Nuclear receptor coactivators: structural and functional biochemistry. Biochemistry. 2011 Jan 25; 50(3):313-28. PMID: 21141906; PMCID: PMC3647688.
    124. Louet JF, Chopra AR, Sagen JV, An J, York B, Tannour-Louet M, Saha PK, Stevens RD, Wenner BR, Ilkayeva OR, Bain JR, Zhou S, DeMayo F, Xu J, Newgard CB, O'Malley BW. The coactivator SRC-1 is an essential coordinator of hepatic glucose production. Cell Metab. 2010 Dec 1; 12(6):606-18. PMID: 21109193; PMCID: PMC3024581.
    125. Lydon JP, O'Malley BW. Minireview: steroid receptor coactivator-3: a multifarious coregulator in mammary gland metastasis. Endocrinology. 2011 Jan; 152(1):19-25. PMID: 21047941; PMCID: PMC3219052.
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    127. McKenna NJ, O'Malley BW. SnapShot: NR coregulators. Cell. 2010 Oct 1; 143(1):172-172.e1. PMID: 20887900.
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    128. McKenna NJ, O'Malley BW. SnapShot: Nuclear receptors II. Cell. 2010 Sep 17; 142(6):986.e1. PMID: 20850017.
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    129. McKenna NJ, O'Malley BW. SnapShot: Nuclear receptors I. Cell. 2010 Sep 3; 142(5):822-822.e1. PMID: 20813267.
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    130. Brisken C, O'Malley B. Hormone action in the mammary gland. Cold Spring Harb Perspect Biol. 2010 Dec; 2(12):a003178. PMID: 20739412; PMCID: PMC2982168.
    131. Quon H, O'Malley BW, Weinstein GS. Transoral robotic surgery and a paradigm shift in the management of oropharyngeal squamous cell carcinoma. J Robot Surg. 2010 Aug; 4(2):79-86. PMID: 27628771.
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    132. Long W, O'Malley BW. Crosstalk among nuclear receptor coactivators and a membrane receptor promotes tumor cell growth and migration. Cell Cycle. 2010 Jun 15; 9(12):2269-70. PMID: 20519947.
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    133. York B, Yu C, Sagen JV, Liu Z, Nikolai BC, Wu RC, Finegold M, Xu J, O'Malley BW. Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):11122-7. PMID: 20534466; PMCID: PMC2890746.
    134. O'Malley BW. Masters of the genome. Nat Rev Mol Cell Biol. 2010 May; 11(5):311. PMID: 20422740.
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    135. Foulds CE, Tsimelzon A, Long W, Le A, Tsai SY, Tsai MJ, O'Malley BW. Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene. Mol Endocrinol. 2010 May; 24(5):1090-105. PMID: 20219889; PMCID: PMC2870939.
    136. Lanz RB, Bulynko Y, Malovannaya A, Labhart P, Wang L, Li W, Qin J, Harper M, O'Malley BW. Global characterization of transcriptional impact of the SRC-3 coregulator. Mol Endocrinol. 2010 Apr; 24(4):859-72. PMID: 20181721; PMCID: PMC2852354.
    137. Fu X, Yucer N, Liu S, Li M, Yi P, Mu JJ, Yang T, Chu J, Jung SY, O'Malley BW, Gu W, Qin J, Wang Y. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proc Natl Acad Sci U S A. 2010 Mar 9; 107(10):4579-84. PMID: 20173098; PMCID: PMC2842028.
    138. Long W, Yi P, Amazit L, LaMarca HL, Ashcroft F, Kumar R, Mancini MA, Tsai SY, Tsai MJ, O'Malley BW. SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell. 2010 Feb 12; 37(3):321-32. PMID: 20159552; PMCID: PMC2824333.
    139. Malovannaya A, Li Y, Bulynko Y, Jung SY, Wang Y, Lanz RB, O'Malley BW, Qin J. Streamlined analysis schema for high-throughput identification of endogenous protein complexes. Proc Natl Acad Sci U S A. 2010 Feb 9; 107(6):2431-6. PMID: 20133760; PMCID: PMC2823922.
    140. Stanisi? V, Lonard DM, O'Malley BW. Modulation of steroid hormone receptor activity. Prog Brain Res. 2010; 181:153-76. PMID: 20478437.
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    141. Stanišic V, Lonard DM, O'Malley BW. Estrogen receptor-a: molecular mechanisms and interactions with the ubiquitin proteasome system. Horm Mol Biol Clin Investig. 2010 Jan; 1(1):1-9. PMID: 25961966.
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    142. Han SJ, O'Malley BW, DeMayo FJ. An estrogen receptor alpha activity indicator model in mice. Genesis. 2009 Dec; 47(12):815-24. PMID: 19882671; PMCID: PMC2794894.
    143. Malik S, Jiang S, Garee JP, Verdin E, Lee AV, O'Malley BW, Zhang M, Belaguli NS, Oesterreich S. Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM. Mol Cell Biol. 2010 Jan; 30(2):399-412. PMID: 19917725; PMCID: PMC2798473.
    144. Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, Naitou M, Takeyama K, Minami Y, O'Malley BW, Kato S. Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell. 2009 Oct 23; 36(2):340-7. PMID: 19854141.
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    145. Lonard DM, Kumar R, O'Malley BW. Minireview: the SRC family of coactivators: an entrée to understanding a subset of polygenic diseases? Mol Endocrinol. 2010 Feb; 24(2):279-85. PMID: 19846539; PMCID: PMC2817609.
    146. O'Malley BW, Kumar R. Nuclear receptor coregulators in cancer biology. Cancer Res. 2009 Nov 1; 69(21):8217-22. PMID: 19843848; PMCID: PMC2783444.
    147. Feng Q, He B, Jung SY, Song Y, Qin J, Tsai SY, Tsai MJ, O'Malley BW. Biochemical control of CARM1 enzymatic activity by phosphorylation. J Biol Chem. 2009 Dec 25; 284(52):36167-74. PMID: 19843527; PMCID: PMC2794732.
    148. Lonard DM, O'Malley BW. Emerging roles of the ubiquitin proteasome system in nuclear hormone receptor signaling. Prog Mol Biol Transl Sci. 2009; 87:117-35. PMID: 20374703.
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    149. Xu J, Wu RC, O'Malley BW. Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nat Rev Cancer. 2009 Sep; 9(9):615-30. PMID: 19701241; PMCID: PMC2908510.
    150. Mödder UI, Monroe DG, Fraser DG, Spelsberg TC, Rosen CJ, Géhin M, Chambon P, O'Malley BW, Khosla S. Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2. J Biol Chem. 2009 Jul 10; 284(28):18767-77. PMID: 19423703; PMCID: PMC2707192.
    151. McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW. Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol. 2009 Jun; 23(6):740-6. PMID: 19423650; PMCID: PMC2691684.
    152. Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH. Foxa2-dependent hepatic gene regulatory networks depend on physiological state. Physiol Genomics. 2009 Jul 9; 38(2):186-95. PMID: 19417011; PMCID: PMC2712224.
    153. Stanisi? V, Malovannaya A, Qin J, Lonard DM, O'Malley BW. OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity. J Biol Chem. 2009 Jun 12; 284(24):16135-45. PMID: 19383985; PMCID: PMC2713518.
    154. O'Malley BW. The "fourth dimension" of gene transcription. Mol Endocrinol. 2009 May; 23(5):587-9. PMID: 19221049; PMCID: PMC2675955.
    155. Wang S, Yuan Y, Liao L, Kuang SQ, Tien JC, O'Malley BW, Xu J. Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proc Natl Acad Sci U S A. 2009 Jan 6; 106(1):151-6. PMID: 19109434; PMCID: PMC2629242.
    156. Chopra AR, Louet JF, Saha P, An J, Demayo F, Xu J, York B, Karpen S, Finegold M, Moore D, Chan L, Newgard CB, O'Malley BW. Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science. 2008 Nov 28; 322(5906):1395-9. PMID: 19039140; PMCID: PMC2668604.
    157. Han SJ, Lonard DM, O'Malley BW. Multi-modulation of nuclear receptor coactivators through posttranslational modifications. Trends Endocrinol Metab. 2009 Jan; 20(1):8-15. PMID: 19019695; PMCID: PMC3642869.
    158. Coste A, Louet JF, Lagouge M, Lerin C, Antal MC, Meziane H, Schoonjans K, Puigserver P, O'Malley BW, Auwerx J. The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. Proc Natl Acad Sci U S A. 2008 Nov 4; 105(44):17187-92. PMID: 18957541; PMCID: PMC2579399.
    159. O'Malley B. The Year in Basic Science: nuclear receptors and coregulators. Mol Endocrinol. 2008 Dec; 22(12):2751-8. PMID: 18845672.
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    160. Kang YK, Schiff R, Ko L, Wang T, Tsai SY, Tsai MJ, O'Malley BW. Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis. Cancer Res. 2008 Oct 1; 68(19):7887-96. PMID: 18829545; PMCID: PMC2597518.
    161. Li C, Liang YY, Feng XH, Tsai SY, Tsai MJ, O'Malley BW. Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. Mol Cell. 2008 Sep 26; 31(6):835-49. PMID: 18922467; PMCID: PMC2597059.
    162. O'Malley BW, McKenna NJ. Coactivators and corepressors: what's in a name? Mol Endocrinol. 2008 Oct; 22(10):2213-4. PMID: 18701638; PMCID: PMC2582534.
    163. Qin L, Liao L, Redmond A, Young L, Yuan Y, Chen H, O'Malley BW, Xu J. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol Cell Biol. 2008 Oct; 28(19):5937-50. PMID: 18644862; PMCID: PMC2547002.
    164. O'Malley BW, Qin J, Lanz RB. Cracking the coregulator codes. Curr Opin Cell Biol. 2008 Jun; 20(3):310-5. PMID: 18499426; PMCID: PMC3647352.
    165. Fereshteh MP, Tilli MT, Kim SE, Xu J, O'Malley BW, Wellstein A, Furth PA, Riegel AT. The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Res. 2008 May 15; 68(10):3697-706. PMID: 18483252; PMCID: PMC3641830.
    166. Lonard DM, O'Malley BW. Gene transcription: two worlds merged. Nature. 2008 Apr 24; 452(7190):946-7. PMID: 18432236.
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    167. Lonard DM, O'Malley BW. SRC-3 transcription-coupled activation, degradation, and the ubiquitin clock: is there enough coactivator to go around in cells? Sci Signal. 2008; 1(13):pe16. PMID: 18385039.
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    168. Yi P, Feng Q, Amazit L, Lonard DM, Tsai SY, Tsai MJ, O'Malley BW. Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell. 2008 Feb 29; 29(4):465-76. PMID: 18313384; PMCID: PMC2293272.
    169. Rickard DJ, Iwaniec UT, Evans G, Hefferan TE, Hunter JC, Waters KM, Lydon JP, O'Malley BW, Khosla S, Spelsberg TC, Turner RT. Bone growth and turnover in progesterone receptor knockout mice. Endocrinology. 2008 May; 149(5):2383-90. PMID: 18276762; PMCID: PMC2329269.
    170. Loehberg CR, Thompson T, Kastan MB, Maclean KH, Edwards DG, Kittrell FS, Medina D, Conneely OM, O'Malley BW. Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis. Cancer Res. 2007 Dec 15; 67(24):12026-33. PMID: 18089834.
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    171. Mödder UI, Sanyal A, Xu J, O'Malley BW, Spelsberg TC, Khosla S. The skeletal response to estrogen is impaired in female but not in male steroid receptor coactivator (SRC)-1 knock out mice. Bone. 2008 Feb; 42(2):414-21. PMID: 18055287; PMCID: PMC2248556.
    172. He B, Feng Q, Mukherjee A, Lonard DM, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. A repressive role for prohibitin in estrogen signaling. Mol Endocrinol. 2008 Feb; 22(2):344-60. PMID: 17932104; PMCID: PMC2234581.
    173. Jordan VC, O'Malley BW. Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. J Clin Oncol. 2007 Dec 20; 25(36):5815-24. PMID: 17893378.
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    174. Lonard DM, O'malley BW. Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation. Mol Cell. 2007 Sep 7; 27(5):691-700. PMID: 17803935.
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    175. Amazit L, Pasini L, Szafran AT, Berno V, Wu RC, Mielke M, Jones ED, Mancini MG, Hinojos CA, O'Malley BW, Mancini MA. Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Mol Cell Biol. 2007 Oct; 27(19):6913-32. PMID: 17646391; PMCID: PMC2099228.
    176. Louet JF, O'Malley BW. Coregulators in adipogenesis: what could we learn from the SRC (p160) coactivator family? Cell Cycle. 2007 Oct 15; 6(20):2448-52. PMID: 17704643.
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    177. Lonard DM, Lanz RB, O'Malley BW. Nuclear receptor coregulators and human disease. Endocr Rev. 2007 Aug; 28(5):575-87. PMID: 17609497.
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    178. Li X, Amazit L, Long W, Lonard DM, Monaco JJ, O'Malley BW. Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway. Mol Cell. 2007 Jun 22; 26(6):831-42. PMID: 17588518.
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    179. Wu RC, Feng Q, Lonard DM, O'Malley BW. SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. Cell. 2007 Jun 15; 129(6):1125-40. PMID: 17574025.
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    180. Jeong JW, Lee KY, Han SJ, Aronow BJ, Lydon JP, O'Malley BW, DeMayo FJ. The p160 steroid receptor coactivator 2, SRC-2, regulates murine endometrial function and regulates progesterone-independent and -dependent gene expression. Endocrinology. 2007 Sep; 148(9):4238-50. PMID: 17556502.
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    181. Fukuda T, Yamagata K, Fujiyama S, Matsumoto T, Koshida I, Yoshimura K, Mihara M, Naitou M, Endoh H, Nakamura T, Akimoto C, Yamamoto Y, Katagiri T, Foulds C, Takezawa S, Kitagawa H, Takeyama K, O'Malley BW, Kato S. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol. 2007 May; 9(5):604-11. PMID: 17435748.
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    182. Meng Q, Rayala SK, Gururaj AE, Talukder AH, O'Malley BW, Kumar R. Signaling-dependent and coordinated regulation of transcription, splicing, and translation resides in a single coregulator, PCBP1. Proc Natl Acad Sci U S A. 2007 Apr 3; 104(14):5866-71. PMID: 17389360; PMCID: PMC1851583.
    183. Yu C, York B, Wang S, Feng Q, Xu J, O'Malley BW. An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Mol Cell. 2007 Mar 9; 25(5):765-78. PMID: 17349961; PMCID: PMC1864954.
    184. Auboeuf D, Batsché E, Dutertre M, Muchardt C, O'Malley BW. Coregulators: transducing signal from transcription to alternative splicing. Trends Endocrinol Metab. 2007 Apr; 18(3):122-9. PMID: 17320409.
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    185. Han SJ, Tsai SY, Tsai MJ, O'Malley BW. Distinct temporal and spatial activities of RU486 on progesterone receptor function in reproductive organs of ovariectomized mice. Endocrinology. 2007 May; 148(5):2471-86. PMID: 17303655.
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    186. O'Malley BW. Coregulators: from whence came these "master genes". Mol Endocrinol. 2007 May; 21(5):1009-13. PMID: 17284664.
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    187. Han SJ, DeMayo FJ, O'Malley BW. Dynamic regulation of progesterone receptor activity in female reproductive tissues. Ernst Schering Found Symp Proc. 2007; (1):25-43. PMID: 18543433.
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    188. Mukherjee A, Amato P, Craig-Allred D, DeMayo FJ, O'Malley BW, Lydon JP. Steroid receptor coactivator 2: an essential coregulator of progestin-induced uterine and mammary morphogenesis. Ernst Schering Found Symp Proc. 2007; (1):55-76. PMID: 18540568.
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    189. Li C, Wu RC, Amazit L, Tsai SY, Tsai MJ, O'Malley BW. Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover. Mol Cell Biol. 2007 Feb; 27(4):1296-308. PMID: 17158932; PMCID: PMC1800725.
    190. Louet JF, Coste A, Amazit L, Tannour-Louet M, Wu RC, Tsai SY, Tsai MJ, Auwerx J, O'Malley BW. Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17868-73. PMID: 17098861; PMCID: PMC1693839.
    191. Mussi P, Liao L, Park SE, Ciana P, Maggi A, Katzenellenbogen BS, Xu J, O'Malley BW. Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland. Proc Natl Acad Sci U S A. 2006 Nov 7; 103(45):16716-21. PMID: 17065319; PMCID: PMC1636521.
    192. Mukherjee A, Amato P, Allred DC, Fernandez-Valdivia R, Nguyen J, O'Malley BW, DeMayo FJ, Lydon JP. Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: insights from the mouse--implications for the human. J Steroid Biochem Mol Biol. 2006 Dec; 102(1-5):22-31. PMID: 17045797.
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    193. O'Malley BW. Molecular biology. Little molecules with big goals. Science. 2006 Sep 22; 313(5794):1749-50. PMID: 16990541.
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    194. Mukherjee A, Soyal SM, Fernandez-Valdivia R, Gehin M, Chambon P, Demayo FJ, Lydon JP, O'Malley BW. Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol. 2006 Sep; 26(17):6571-83. PMID: 16914740; PMCID: PMC1592830.
    195. Feng Q, Yi P, Wong J, O'Malley BW. Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly. Mol Cell Biol. 2006 Nov; 26(21):7846-57. PMID: 16923966; PMCID: PMC1636757.
    196. Mussi P, Yu C, O'Malley BW, Xu J. Stimulation of steroid receptor coactivator-3 (SRC-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3. Mol Endocrinol. 2006 Dec; 20(12):3105-19. PMID: 16916939.
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    197. Han SJ, Jung SY, Malovannaya A, Kim T, Lanz RB, Qin J, O'Malley BW. A scoring system for the follow up study of nuclear receptor coactivator complexes. Nucl Recept Signal. 2006; 4:e014. PMID: 16862220; PMCID: PMC1513068.
    198. Dhananjayan SC, Ramamoorthy S, Khan OY, Ismail A, Sun J, Slingerland J, O'Malley BW, Nawaz Z. WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors. Mol Endocrinol. 2006 Oct; 20(10):2343-54. PMID: 16772533.
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    199. Hatchell EC, Colley SM, Beveridge DJ, Epis MR, Stuart LM, Giles KM, Redfern AD, Miles LE, Barker A, MacDonald LM, Arthur PG, Lui JC, Golding JL, McCulloch RK, Metcalf CB, Wilce JA, Wilce MC, Lanz RB, O'Malley BW, Leedman PJ. SLIRP, a small SRA binding protein, is a nuclear receptor corepressor. Mol Cell. 2006 Jun 9; 22(5):657-68. PMID: 16762838.
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    200. Lonard DM, O'Malley BW. The expanding cosmos of nuclear receptor coactivators. Cell. 2006 May 5; 125(3):411-4. PMID: 16678083.
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    201. Coste A, Antal MC, Chan S, Kastner P, Mark M, O'Malley BW, Auwerx J. Absence of the steroid receptor coactivator-3 induces B-cell lymphoma. EMBO J. 2006 Jun 7; 25(11):2453-64. PMID: 16675958; PMCID: PMC1478181.
    202. Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW, Chatterjee SK. Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells. J Cell Biochem. 2006 Apr 1; 97(5):1036-51. PMID: 16294321.
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    203. Frye CA, Sumida K, Lydon JP, O'Malley BW, Pfaff DW. Mid-aged and aged wild-type and progestin receptor knockout (PRKO) mice demonstrate rapid progesterone and 3alpha,5alpha-THP-facilitated lordosis. Psychopharmacology (Berl). 2006 May; 185(4):423-32. PMID: 16544163.
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    204. Frye CA, Sumida K, Dudek BC, Harney JP, Lydon JP, O'Malley BW, Pfaff DW, Rhodes ME. Progesterone's effects to reduce anxiety behavior of aged mice do not require actions via intracellular progestin receptors. Psychopharmacology (Berl). 2006 Jun; 186(3):312-22. PMID: 16538472.
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    205. Woolley SC, O'Malley B, Lydon J, Crews D. Genotype differences in behavior and tyrosine hydroxylase expression between wild-type and progesterone receptor knockout mice. Behav Brain Res. 2006 Feb 28; 167(2):197-204. PMID: 16413068.
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    206. Li X, Lonard DM, Jung SY, Malovannaya A, Feng Q, Qin J, Tsai SY, Tsai MJ, O'Malley BW. The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell. 2006 Jan 27; 124(2):381-92. PMID: 16439211.
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    207. Jeong JW, Kwak I, Lee KY, White LD, Wang XP, Brunicardi FC, O'Malley BW, DeMayo FJ. The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism. Mol Endocrinol. 2006 May; 20(5):1138-52. PMID: 16423883.
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    208. Winnay JN, Xu J, O'Malley BW, Hammer GD. Steroid receptor coactivator-1-deficient mice exhibit altered hypothalamic-pituitary-adrenal axis function. Endocrinology. 2006 Mar; 147(3):1322-32. PMID: 16339206.
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    209. Yi P, Wu RC, Sandquist J, Wong J, Tsai SY, Tsai MJ, Means AR, O'Malley BW. Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol. 2005 Nov; 25(21):9687-99. PMID: 16227615; PMCID: PMC1265806.
    210. Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW, Chatterjee SK. Inhibition of NK cell activity through TGF-beta 1 by down-regulation of NKG2D in a murine model of head and neck cancer. J Immunol. 2005 Oct 15; 175(8):5541-50. PMID: 16210663.
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    211. Schillinger KJ, Tsai SY, Taffet GE, Reddy AK, Marian AJ, Entman ML, Oka K, Chan L, O'Malley BW. Regulatable atrial natriuretic peptide gene therapy for hypertension. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):13789-94. PMID: 16162668; PMCID: PMC1236585.
    212. Han SJ, Jeong J, Demayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice. Mol Cell Biol. 2005 Sep; 25(18):8150-65. PMID: 16135805; PMCID: PMC1234322.
    213. Zheng FF, Wu RC, Smith CL, O'Malley BW. Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor. Mol Cell Biol. 2005 Sep; 25(18):8273-84. PMID: 16135815; PMCID: PMC1234335.
    214. Ying H, Furuya F, Willingham MC, Xu J, O'Malley BW, Cheng SY. Dual functions of the steroid hormone receptor coactivator 3 in modulating resistance to thyroid hormone. Mol Cell Biol. 2005 Sep; 25(17):7687-95. PMID: 16107715; PMCID: PMC1190271.
    215. Han SJ, DeMayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol. 2006 Jan; 20(1):45-55. PMID: 16141356.
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    216. Kuang SQ, Liao L, Wang S, Medina D, O'Malley BW, Xu J. Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Res. 2005 Sep 1; 65(17):7993-8002. PMID: 16140972.
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    217. McKenna NJ, O'Malley BW. Teaching resources. An interactive course in nuclear receptor signaling: concepts and models. Sci STKE. 2005 Aug 30; 2005(299):tr22. PMID: 16131668.
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    218. Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW, Chatterjee SK. Recombinant vaccinia virus expressing interleukin-2 invokes anti-tumor cellular immunity in an orthotopic murine model of head and neck squamous cell carcinoma. Mol Ther. 2006 Jan; 13(1):183-93. PMID: 16125469.
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    219. Jung SY, Malovannaya A, Wei J, O'Malley BW, Qin J. Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes. Mol Endocrinol. 2005 Oct; 19(10):2451-65. PMID: 16051665.
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    220. Margolis RN, Evans RM, O'Malley BW. The Nuclear Receptor Signaling Atlas: development of a functional atlas of nuclear receptors. Mol Endocrinol. 2005 Oct; 19(10):2433-6. PMID: 16051673.
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    221. Schneider JS, Burgess C, Sleiter NC, DonCarlos LL, Lydon JP, O'Malley B, Levine JE. Enhanced sexual behaviors and androgen receptor immunoreactivity in the male progesterone receptor knockout mouse. Endocrinology. 2005 Oct; 146(10):4340-8. PMID: 16002522.
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    222. Auboeuf D, Dowhan DH, Dutertre M, Martin N, Berget SM, O'Malley BW. A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts. Mol Cell Biol. 2005 Jul; 25(13):5307-16. PMID: 15964789; PMCID: PMC1156981.
    223. Ye X, Han SJ, Tsai SY, DeMayo FJ, Xu J, Tsai MJ, O'Malley BW. Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice. Proc Natl Acad Sci U S A. 2005 Jul 5; 102(27):9487-92. PMID: 15983373; PMCID: PMC1172261.
    224. Apostolakis EM, Riherd DN, O'Malley BW. PAC1 receptors mediate pituitary adenylate cyclase-activating polypeptide- and progesterone-facilitated receptivity in female rats. Mol Endocrinol. 2005 Nov; 19(11):2798-811. PMID: 15976009.
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    225. O'Malley BW. A life-long search for the molecular pathways of steroid hormone action. Mol Endocrinol. 2005 Jun; 19(6):1402-11. PMID: 15914709.
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    226. Masuhiro Y, Mezaki Y, Sakari M, Takeyama K, Yoshida T, Inoue K, Yanagisawa J, Hanazawa S, O'malley BW, Kato S. Splicing potentiation by growth factor signals via estrogen receptor phosphorylation. Proc Natl Acad Sci U S A. 2005 Jun 7; 102(23):8126-31. PMID: 15919818; PMCID: PMC1149443.
    227. Wu RC, Smith CL, O'Malley BW. Transcriptional regulation by steroid receptor coactivator phosphorylation. Endocr Rev. 2005 May; 26(3):393-9. PMID: 15814849.
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    228. Park KJ, Krishnan V, O'Malley BW, Yamamoto Y, Gaynor RB. Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation. Mol Cell. 2005 Apr 1; 18(1):71-82. PMID: 15808510.
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    229. Lonard DM, O'Malley BW. Expanding functional diversity of the coactivators. Trends Biochem Sci. 2005 Mar; 30(3):126-32. PMID: 15752984.
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    230. Park SE, Xu J, Frolova A, Liao L, O'Malley BW, Katzenellenbogen BS. Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo. Mol Cell Biol. 2005 Mar; 25(5):1989-99. PMID: 15713652; PMCID: PMC549370.
    231. Dennis AP, Lonard DM, Nawaz Z, O'Malley BW. Inhibition of the 26S proteasome blocks progesterone receptor-dependent transcription through failed recruitment of RNA polymerase II. J Steroid Biochem Mol Biol. 2005 Mar; 94(4):337-46. PMID: 15857753.
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    232. Dennis AP, O'Malley BW. Rush hour at the promoter: how the ubiquitin-proteasome pathway polices the traffic flow of nuclear receptor-dependent transcription. J Steroid Biochem Mol Biol. 2005 Feb; 93(2-5):139-51. PMID: 15860256.
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    233. Dowhan DH, Hong EP, Auboeuf D, Dennis AP, Wilson MM, Berget SM, O'Malley BW. Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta. Mol Cell. 2005 Feb 4; 17(3):429-39. PMID: 15694343.
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    234. Labhart P, Karmakar S, Salicru EM, Egan BS, Alexiadis V, O'Malley BW, Smith CL. Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator. Proc Natl Acad Sci U S A. 2005 Feb 1; 102(5):1339-44. PMID: 15677324; PMCID: PMC547886.
    235. Reddy DS, O'Malley BW, Rogawski MA. Anxiolytic activity of progesterone in progesterone receptor knockout mice. Neuropharmacology. 2005 Jan; 48(1):14-24. PMID: 15617723.
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    236. Nishihara E, O'Malley BW, Xu J. Nuclear receptor coregulators are new players in nervous system development and function. Mol Neurobiol. 2004 Dec; 30(3):307-25. PMID: 15655254.
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    237. O'Malley BW. Results of a search for the mechanisms of steroid receptor regulation of gene expression. Ann N Y Acad Sci. 2004 Dec; 1038:80-7. PMID: 15838100.
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    238. Wu HY, Hamamori Y, Xu J, Chang SC, Saluna T, Chang MF, O'Malley BW, Kedes L. Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD. J Biol Chem. 2005 Feb 4; 280(5):3129-37. PMID: 15563453.
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    239. Li X, Lonard DM, O'Malley BW. A contemporary understanding of progesterone receptor function. Mech Ageing Dev. 2004 Oct-Nov; 125(10-11):669-78. PMID: 15541762.
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    240. Verma S, Ismail A, Gao X, Fu G, Li X, O'Malley BW, Nawaz Z. The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors. Mol Cell Biol. 2004 Oct; 24(19):8716-26. PMID: 15367689; PMCID: PMC516762.
    241. Wu RC, Qin J, Yi P, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell. 2004 Sep 24; 15(6):937-49. PMID: 15383283.
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    242. Mark M, Yoshida-Komiya H, Gehin M, Liao L, Tsai MJ, O'Malley BW, Chambon P, Xu J. Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4453-8. PMID: 15070739; PMCID: PMC384768.
    243. Mollenhauer J, Helmke B, Medina D, Bergmann G, Gassler N, Müller H, Lyer S, Diedrichs L, Renner M, Wittig R, Blaich S, Hamann U, Madsen J, Holmskov U, Bikker F, Ligtenberg A, Carlén A, Olsson J, Otto HF, O'Malley B, Poustka A. Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis. Genes Chromosomes Cancer. 2004 Mar; 39(3):185-94. PMID: 14732920.
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    244. Kuang SQ, Liao L, Zhang H, Lee AV, O'Malley BW, Xu J. AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice. Cancer Res. 2004 Mar 1; 64(5):1875-85. PMID: 14996752.
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    245. Auboeuf D, Dowhan DH, Kang YK, Larkin K, Lee JW, Berget SM, O'Malley BW. Differential recruitment of nuclear receptor coactivators may determine alternative RNA splice site choice in target genes. Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8):2270-4. PMID: 14982999; PMCID: PMC356940.
    246. Reddy DS, Castaneda DC, O'Malley BW, Rogawski MA. Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice. J Pharmacol Exp Ther. 2004 Jul; 310(1):230-9. PMID: 14982969.
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    247. Smith CL, O'Malley BW. Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev. 2004 Feb; 25(1):45-71. PMID: 14769827.
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    248. Auboeuf D, Dowhan DH, Li X, Larkin K, Ko L, Berget SM, O'Malley BW. CoAA, a nuclear receptor coactivator protein at the interface of transcriptional coactivation and RNA splicing. Mol Cell Biol. 2004 Jan; 24(1):442-53. PMID: 14673176; PMCID: PMC303353.
    249. Lonard DM, Tsai SY, O'Malley BW. Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins. Mol Cell Biol. 2004 Jan; 24(1):14-24. PMID: 14673139; PMCID: PMC303341.
    250. Nawaz Z, O'Malley BW. Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription? Mol Endocrinol. 2004 Mar; 18(3):493-9. PMID: 14673136.
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    251. Ismail PM, Amato P, Soyal SM, DeMayo FJ, Conneely OM, O'Malley BW, Lydon JP. Progesterone involvement in breast development and tumorigenesis--as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids. 2003 Nov; 68(10-13):779-87. PMID: 14667968.
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    252. Apostolakis EM, Lanz R, O'Malley BW. Pituitary adenylate cyclase-activating peptide: a pivotal modulator of steroid-induced reproductive behavior in female rodents. Mol Endocrinol. 2004 Jan; 18(1):173-83. PMID: 14593074.
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    253. O'Malley BW. Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression. Nucl Recept Signal. 2003; 1:e010. PMID: 16604182; PMCID: PMC1402223.
    254. Mödder UI, Sanyal A, Kearns AE, Sibonga JD, Nishihara E, Xu J, O'Malley BW, Ritman EL, Riggs BL, Spelsberg TC, Khosla S. Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology. 2004 Feb; 145(2):913-21. PMID: 14563705.
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    255. Lanz RB, Chua SS, Barron N, Söder BM, DeMayo F, O'Malley BW. Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo. Mol Cell Biol. 2003 Oct; 23(20):7163-76. PMID: 14517287; PMCID: PMC230309.
    256. Kamiya Y, Zhang XY, Ying H, Kato Y, Willingham MC, Xu J, O'Malley BW, Cheng SY. Modulation by steroid receptor coactivator-1 of target-tissue responsiveness in resistance to thyroid hormone. Endocrinology. 2003 Sep; 144(9):4144-53. PMID: 12933689.
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    257. Lan ZJ, Gu P, Xu X, Jackson KJ, DeMayo FJ, O'Malley BW, Cooney AJ. GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility. EMBO J. 2003 Aug 15; 22(16):4070-81. PMID: 12912906; PMCID: PMC175795.
    258. Dasgupta S, Tripathi PK, Bhattacharya-Chatterjee M, O'Malley B, Chatterjee SK. Recombinant vaccinia virus expressing IL-2 generates effective anti-tumor responses in an orthotopic murine model of head and neck carcinoma. Mol Ther. 2003 Aug; 8(2):238-48. PMID: 12907146.
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    259. Ghoumari AM, Ibanez C, El-Etr M, Leclerc P, Eychenne B, O'Malley BW, Baulieu EE, Schumacher M. Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum. J Neurochem. 2003 Aug; 86(4):848-59. PMID: 12887683.
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    260. Li X, O'Malley BW. Unfolding the action of progesterone receptors. J Biol Chem. 2003 Oct 10; 278(41):39261-4. PMID: 12893816.
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    261. Monks DA, Xu J, O'Malley BW, Jordan CL. Steroid receptor coactivator-1 is not required for androgen-mediated sexual differentiation of spinal motoneurons. Neuroendocrinology. 2003 Jul; 78(1):45-51. PMID: 12869799.
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    262. Li X, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol. 2003 Jun; 23(11):3763-73. PMID: 12748280; PMCID: PMC155204.
    263. Sadow PM, Chassande O, Koo EK, Gauthier K, Samarut J, Xu J, O'Malley BW, Weiss RE. Regulation of expression of thyroid hormone receptor isoforms and coactivators in liver and heart by thyroid hormone. Mol Cell Endocrinol. 2003 May 30; 203(1-2):65-75. PMID: 12782404.
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    264. Rance J, Phillips C, Davies S, O'Malley B, Zaman Q, Price D. How much of a priority is treating erectile dysfunction? A study of patients' perceptions. Diabet Med. 2003 Mar; 20(3):205-9. PMID: 12675664.
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    265. Schneider JS, Stone MK, Wynne-Edwards KE, Horton TH, Lydon J, O'Malley B, Levine JE. Progesterone receptors mediate male aggression toward infants. Proc Natl Acad Sci U S A. 2003 Mar 4; 100(5):2951-6. PMID: 12601162; PMCID: PMC151447.
    266. Sadow PM, Koo E, Chassande O, Gauthier K, Samarut J, Xu J, O'Malley BW, Seo H, Murata Y, Weiss RE. Thyroid hormone receptor-specific interactions with steroid receptor coactivator-1 in the pituitary. Mol Endocrinol. 2003 May; 17(5):882-94. PMID: 12576486.
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    267. Cheskis BJ, McKenna NJ, Wong CW, Wong J, Komm B, Lyttle CR, O'Malley BW. Hierarchical affinities and a bipartite interaction model for estrogen receptor isoforms and full-length steroid receptor coactivator (SRC/p160) family members. J Biol Chem. 2003 Apr 11; 278(15):13271-7. PMID: 12540843.
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    268. Nishihara E, Yoshida-Komiya H, Chan CS, Liao L, Davis RL, O'Malley BW, Xu J. SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells. J Neurosci. 2003 Jan 1; 23(1):213-22. PMID: 12514218.
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    269. Picard F, Géhin M, Annicotte J, Rocchi S, Champy MF, O'Malley BW, Chambon P, Auwerx J. SRC-1 and TIF2 control energy balance between white and brown adipose tissues. Cell. 2002 Dec 27; 111(7):931-41. PMID: 12507421.
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    270. Liao L, Kuang SQ, Yuan Y, Gonzalez SM, O'Malley BW, Xu J. Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. J Steroid Biochem Mol Biol. 2002 Dec; 83(1-5):3-14. PMID: 12650696.
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    271. Lanz RB, Razani B, Goldberg AD, O'Malley BW. Distinct RNA motifs are important for coactivation of steroid hormone receptors by steroid receptor RNA activator (SRA). Proc Natl Acad Sci U S A. 2002 Dec 10; 99(25):16081-6. PMID: 12444263; PMCID: PMC138568.
    272. Picard F, Wanatabe M, Schoonjans K, Lydon J, O'Malley BW, Auwerx J. Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation. Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15644-8. PMID: 12438645; PMCID: PMC137770.
    273. Ismail PM, Li J, DeMayo FJ, O'Malley BW, Lydon JP. A novel LacZ reporter mouse reveals complex regulation of the progesterone receptor promoter during mammary gland development. Mol Endocrinol. 2002 Nov; 16(11):2475-89. PMID: 12403837.
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    274. Auboeuf D, Hönig A, Berget SM, O'Malley BW. Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science. 2002 Oct 11; 298(5592):416-9. PMID: 12376702.
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    275. Sadow PM, Chassande O, Gauthier K, Samarut J, Xu J, O'Malley BW, Weiss RE. Specificity of thyroid hormone receptor subtype and steroid receptor coactivator-1 on thyroid hormone action. Am J Physiol Endocrinol Metab. 2003 Jan; 284(1):E36-46. PMID: 12388168.
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    276. Xu J, O'Malley BW. Molecular mechanisms and cellular biology of the steroid receptor coactivator (SRC) family in steroid receptor function. Rev Endocr Metab Disord. 2002 Sep; 3(3):185-92. PMID: 12215713.
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    277. Hönig A, Auboeuf D, Parker MM, O'Malley BW, Berget SM. Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72. Mol Cell Biol. 2002 Aug; 22(16):5698-707. PMID: 12138182; PMCID: PMC133985.
    278. McKenna NJ, O'Malley BW. Minireview: nuclear receptor coactivators--an update. Endocrinology. 2002 Jul; 143(7):2461-5. PMID: 12072374.
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    279. Apostolakis EM, Ramamurphy M, Zhou D, Oñate S, O'Malley BW. Acute disruption of select steroid receptor coactivators prevents reproductive behavior in rats and unmasks genetic adaptation in knockout mice. Mol Endocrinol. 2002 Jul; 16(7):1511-23. PMID: 12089347.
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    280. Cao T, Tsai SY, O'Malley BW, Wang XJ, Roop DR. The epidermis as a bioreactor: topically regulated cutaneous delivery into the circulation. Hum Gene Ther. 2002 Jun 10; 13(9):1075-80. PMID: 12067440.
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    281. Liu Z, Auboeuf D, Wong J, Chen JD, Tsai SY, Tsai MJ, O'Malley BW. Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):7940-4. PMID: 12048256; PMCID: PMC122999.
    282. Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol. 2002 May; 22(10):3549-61. PMID: 11971985; PMCID: PMC133790.
    283. Sivaraman L, Gay J, Hilsenbeck SG, Shine HD, Conneely OM, Medina D, O'Malley BW. Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis. Breast Cancer Res Treat. 2002 May; 73(1):75-83. PMID: 12083633.
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    284. Takeuchi Y, Murata Y, Sadow P, Hayashi Y, Seo H, Xu J, O'Malley BW, Weiss RE, Refetoff S. Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo. Endocrinology. 2002 Apr; 143(4):1346-52. PMID: 11897691.
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    285. Weiss RE, Gehin M, Xu J, Sadow PM, O'Malley BW, Chambon P, Refetoff S. Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency. Endocrinology. 2002 Apr; 143(4):1554-7. PMID: 11897715.
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    286. Takeuchi Y, Murata Y, Sadow P, Hayashi Y, Seo H, Xu J, O'Malley BW, Weiss RE, Refetoff S. Steroid Receptor Coactivator-1 Deficiency Causes Variable Alterations in the Modulation of T3-Regulated Transcription of Genes in Vivo. Endocrinology. 2002 Apr 01; 143(4):1346-1352. PMID: 28201486.
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    287. McKenna NJ, O'Malley BW. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell. 2002 Feb 22; 108(4):465-74. PMID: 11909518.
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    288. Cavarretta IT, Mukopadhyay R, Lonard DM, Cowsert LM, Bennett CF, O'Malley BW, Smith CL. Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation. Mol Endocrinol. 2002 Feb; 16(2):253-70. PMID: 11818499.
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    289. Markaverich B, Mani S, Alejandro MA, Mitchell A, Markaverich D, Brown T, Velez-Trippe C, Murchison C, O'Malley B, Faith R. A novel endocrine-disrupting agent in corn with mitogenic activity in human breast and prostatic cancer cells. Environ Health Perspect. 2002 Feb; 110(2):169-77. PMID: 11836146; PMCID: PMC1240732.
    290. Finn FM, O'Malley BW. Klaus Hofmann, February 21, 1911 - December 25, 1995. Biogr Mem Natl Acad Sci. 2002; 81:116-34. PMID: 12661557.
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    291. Ye X, Schillinger K, Burcin MM, Tsai SY, O'Malley BW. Ligand-inducible transgene regulation for gene therapy. Methods Enzymol. 2002; 346:551-61. PMID: 11883090.
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    292. Smith CL, DeVera DG, Lamb DJ, Nawaz Z, Jiang YH, Beaudet AL, O'Malley BW. Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction. Mol Cell Biol. 2002 Jan; 22(2):525-35. PMID: 11756548; PMCID: PMC139730.
    293. Conneely OM, Mulac-Jericevic B, DeMayo F, Lydon JP, O'Malley BW. Reproductive functions of progesterone receptors. Recent Prog Horm Res. 2002; 57:339-55. PMID: 12017551.
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    294. McKenna NJ, O'Malley BW. Nuclear receptors, coregulators, ligands, and selective receptor modulators: making sense of the patchwork quilt. Ann N Y Acad Sci. 2001 Dec; 949:3-5. PMID: 11795367.
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    295. Liu Z, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12426-31. PMID: 11606780; PMCID: PMC60070.
    296. Sivaraman L, Conneely OM, Medina D, O'Malley BW. p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12379-84. PMID: 11606748; PMCID: PMC60062.
    297. Sivaraman L, Hilsenbeck SG, Zhong L, Gay J, Conneely OM, Medina D, O'Malley BW. Early exposure of the rat mammary gland to estrogen and progesterone blocks co-localization of estrogen receptor expression and proliferation. J Endocrinol. 2001 Oct; 171(1):75-83. PMID: 11572792.
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    298. Karas RH, van Eickels M, Lydon JP, Roddy S, Kwoun M, Aronovitz M, Baur WE, Conneely O, O'Malley BW, Mendelsohn ME. A complex role for the progesterone receptor in the response to vascular injury. J Clin Invest. 2001 Aug; 108(4):611-8. PMID: 11518735; PMCID: PMC209395.
    299. Monitto CL, Berkowitz D, Lee KM, Pin S, Li D, Breslow M, O'Malley B, Schiller M. Differential gene expression in a murine model of cancer cachexia. Am J Physiol Endocrinol Metab. 2001 Aug; 281(2):E289-97. PMID: 11440905.
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    300. Stenoien DL, Nye AC, Mancini MG, Patel K, Dutertre M, O'Malley BW, Smith CL, Belmont AS, Mancini MA. Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells. Mol Cell Biol. 2001 Jul; 21(13):4404-12. PMID: 11390668; PMCID: PMC87100.
    301. Kurita T, Wang YZ, Donjacour AA, Zhao C, Lydon JP, O'Malley BW, Isaacs JT, Dahiya R, Cunha GR. Paracrine regulation of apoptosis by steroid hormones in the male and female reproductive system. Cell Death Differ. 2001 Feb; 8(2):192-200. PMID: 11313721.
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    302. Mani SK, Mitchell A, O'Malley BW. Progesterone receptor and dopamine receptors are required in Delta 9-tetrahydrocannabinol modulation of sexual receptivity in female rats. Proc Natl Acad Sci U S A. 2001 Jan 30; 98(3):1249-54. PMID: 11158625; PMCID: PMC14740.
    303. New MI, Nimkarn S, Brandon DD, Cunningham-Rundles S, Wilson RC, Newfield RS, Vandermeulen J, Barron N, Russo C, Loriaux DL, O'Malley B. Resistance to multiple steroids in two sisters. J Steroid Biochem Mol Biol. 2001 Jan-Mar; 76(1-5):161-6. PMID: 11384874.
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    304. Chung AC, Katz D, Pereira FA, Jackson KJ, DeMayo FJ, Cooney AJ, O'Malley BW. Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation. Mol Cell Biol. 2001 Jan; 21(2):663-77. PMID: 11134352; PMCID: PMC86646.
    305. Stenoien DL, Patel K, Mancini MG, Dutertre M, Smith CL, O'Malley BW, Mancini MA. FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nat Cell Biol. 2001 Jan; 3(1):15-23. PMID: 11146621.
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    306. Rowan BG, Garrison N, Weigel NL, O'Malley BW. 8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein. Mol Cell Biol. 2000 Dec; 20(23):8720-30. PMID: 11073973; PMCID: PMC86491.
    307. McKenna NJ, O'Malley BW. From ligand to response: generating diversity in nuclear receptor coregulator function. J Steroid Biochem Mol Biol. 2000 Nov 30; 74(5):351-6. PMID: 11162944.
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    308. Robker RL, Russell DL, Yoshioka S, Sharma SC, Lydon JP, O'Malley BW, Espey LL, Richards JS. Ovulation: a multi-gene, multi-step process. Steroids. 2000 Oct-Nov; 65(10-11):559-70. PMID: 11108860.
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    309. Rowan BG, O'Malley BW. Progesterone receptor coactivators. Steroids. 2000 Oct-Nov; 65(10-11):545-9. PMID: 11108858.
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    310. Abruzzese RV, Godin D, Mehta V, Perrard JL, French M, Nelson W, Howell G, Coleman M, O'Malley BW, Nordstrom JL. Ligand-dependent regulation of vascular endothelial growth factor and erythropoietin expression by a plasmid-based autoinducible GeneSwitch system. Mol Ther. 2000 Sep; 2(3):276-87. PMID: 10985958.
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    311. McKenna NJ, O'Malley BW. An issue of tissues: divining the split personalities of selective estrogen receptor modulators. Nat Med. 2000 Sep; 6(9):960-2. PMID: 10973303.
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    312. Sivaraman L, Nawaz Z, Medina D, Conneely OM, O'Malley BW. The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis. Breast Cancer Res Treat. 2000 Aug; 62(3):185-95. PMID: 11072783.
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    313. O'Malley B. Citation for the 2000 Edwin B. Astwood Award Lecture of The Endocrine Society to Dr. Jeffrey M. Rosen. Endocr Rev. 2000 Aug; 21(4):449. PMID: 10950163.
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    314. Apostolakis EM, Garai J, Lohmann JE, Clark JH, O'Malley BW. Epidermal growth factor activates reproductive behavior independent of ovarian steroids in female rodents. Mol Endocrinol. 2000 Jul; 14(7):1086-98. PMID: 10894157.
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    315. Xu J, Liao L, Ning G, Yoshida-Komiya H, Deng C, O'Malley BW. The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc Natl Acad Sci U S A. 2000 Jun 6; 97(12):6379-84. PMID: 10823921; PMCID: PMC18611.
    316. Lonard DM, Nawaz Z, Smith CL, O'Malley BW. The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation. Mol Cell. 2000 Jun; 5(6):939-48. PMID: 10911988.
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    317. Robker RL, Russell DL, Espey LL, Lydon JP, O'Malley BW, Richards JS. Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases. Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9):4689-94. PMID: 10781075; PMCID: PMC18294.
    318. Li J, O'Malley BW, Wong J. p300 requires its histone acetyltransferase activity and SRC-1 interaction domain to facilitate thyroid hormone receptor activation in chromatin. Mol Cell Biol. 2000 Mar; 20(6):2031-42. PMID: 10688650; PMCID: PMC110820.
    319. Rowan BG, Weigel NL, O'Malley BW. Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway. J Biol Chem. 2000 Feb 11; 275(6):4475-83. PMID: 10660621.
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    320. Mani SK, Fienberg AA, O'Callaghan JP, Snyder GL, Allen PB, Dash PK, Moore AN, Mitchell AJ, Bibb J, Greengard P, O'Malley BW. Requirement for DARPP-32 in progesterone-facilitated sexual receptivity in female rats and mice. Science. 2000 Feb 11; 287(5455):1053-6. PMID: 10669419.
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    321. Conneely OM, Lydon JP, De Mayo F, O'Malley BW. Reproductive functions of the progesterone receptor. J Soc Gynecol Investig. 2000 Jan-Feb; 7(1 Suppl):S25-32. PMID: 10732326.
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    322. Wang Y, Tsai SY, O'Malley BW. An antiprogestin regulable gene switch for induction of gene expression in vivo. Adv Pharmacol. 2000; 47:343-55. PMID: 10582091.
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    323. Zhou D, Apostolakis EM, O'Malley BW. Distribution of D(5) dopamine receptor mRNA in rat ventromedial hypothalamic nucleus. Biochem Biophys Res Commun. 1999 Dec 20; 266(2):556-9. PMID: 10600540.
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    324. New MI, Nimkarn S, Brandon DD, Cunningham-Rundles S, Wilson RC, Newfield RS, Vandermeulen J, Barron N, Russo C, Loriaux DL, O'Malley B. Resistance to several steroids in two sisters. J Clin Endocrinol Metab. 1999 Dec; 84(12):4454-64. PMID: 10599702.
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    325. Puigserver P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman BM. Activation of PPARgamma coactivator-1 through transcription factor docking. Science. 1999 Nov 12; 286(5443):1368-71. PMID: 10558993.
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    326. Tibbetts TA, DeMayo F, Rich S, Conneely OM, O'Malley BW. Progesterone receptors in the thymus are required for thymic involution during pregnancy and for normal fertility. Proc Natl Acad Sci U S A. 1999 Oct 12; 96(21):12021-6. PMID: 10518569; PMCID: PMC18405.
    327. Smith CL, O'Malley BW. Evolving concepts of selective estrogen receptor action: from basic science to clinical applications. Trends Endocrinol Metab. 1999 Oct; 10(8):299-300. PMID: 10481159.
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    328. Lydon JP, Ge G, Kittrell FS, Medina D, O'Malley BW. Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function. Cancer Res. 1999 Sep 1; 59(17):4276-84. PMID: 10485472.
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    329. Liu Z, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9485-90. PMID: 10449719; PMCID: PMC22235.
    330. Chappell PE, Schneider JS, Kim P, Xu M, Lydon JP, O'Malley BW, Levine JE. Absence of gonadotropin surges and gonadotropin-releasing hormone self-priming in ovariectomized (OVX), estrogen (E2)-treated, progesterone receptor knockout (PRKO) mice. Endocrinology. 1999 Aug; 140(8):3653-8. PMID: 10433223.
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    331. Wang XJ, Liefer KM, Tsai S, O'Malley BW, Roop DR. Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis. Proc Natl Acad Sci U S A. 1999 Jul 20; 96(15):8483-8. PMID: 10411901; PMCID: PMC17542.
    332. Simon C, Hicks MJ, Nemechek AJ, Mehta R, O'Malley BW, Goepfert H, Flaitz CM, Boyd D. PD 098059, an inhibitor of ERK1 activation, attenuates the in vivo invasiveness of head and neck squamous cell carcinoma. Br J Cancer. 1999 Jul; 80(9):1412-9. PMID: 10424744; PMCID: PMC2363077.
    333. Abruzzese RV, Godin D, Burcin M, Mehta V, French M, Li Y, O'Malley BW, Nordstrom JL. Ligand-dependent regulation of plasmid-based transgene expression in vivo. Hum Gene Ther. 1999 Jun 10; 10(9):1499-507. PMID: 10395375.
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    334. McKenna NJ, Lanz RB, O'Malley BW. Nuclear receptor coregulators: cellular and molecular biology. Endocr Rev. 1999 Jun; 20(3):321-44. PMID: 10368774.
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    335. Tibbetts TA, Conneely OM, O'Malley BW. Progesterone via its receptor antagonizes the pro-inflammatory activity of estrogen in the mouse uterus. Biol Reprod. 1999 May; 60(5):1158-65. PMID: 10208978.
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    336. Lanz RB, McKenna NJ, Onate SA, Albrecht U, Wong J, Tsai SY, Tsai MJ, O'Malley BW. A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 1999 Apr 2; 97(1):17-27. PMID: 10199399.
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    337. Weiss RE, Xu J, Ning G, Pohlenz J, O'Malley BW, Refetoff S. Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone. EMBO J. 1999 Apr 1; 18(7):1900-4. PMID: 10202153; PMCID: PMC1171275.
    338. McKenna NJ, Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions. J Steroid Biochem Mol Biol. 1999 Apr-Jun; 69(1-6):3-12. PMID: 10418975.
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    339. Nawaz Z, Lonard DM, Dennis AP, Smith CL, O'Malley BW. Proteasome-dependent degradation of the human estrogen receptor. Proc Natl Acad Sci U S A. 1999 Mar 2; 96(5):1858-62. PMID: 10051559; PMCID: PMC26701.
    340. Nawaz Z, Lonard DM, Smith CL, Lev-Lehman E, Tsai SY, Tsai MJ, O'Malley BW. The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol Cell Biol. 1999 Feb; 19(2):1182-9. PMID: 9891052; PMCID: PMC116047.
    341. Vázquez F, Rodríguez-Manzaneque JC, Lydon JP, Edwards DP, O'Malley BW, Iruela-Arispe ML. Progesterone regulates proliferation of endothelial cells. J Biol Chem. 1999 Jan 22; 274(4):2185-92. PMID: 9890981.
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    342. Burcin MM, Schiedner G, Kochanek S, Tsai SY, O'Malley BW. Adenovirus-mediated regulable target gene expression in vivo. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):355-60. PMID: 9892637; PMCID: PMC15140.
    343. Wang Y, Tsai SY, O'Malley BW. Antiprogestin regulable gene switch for induction of gene expression in vivo. Methods Enzymol. 1999; 306:281-94. PMID: 10432460.
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    344. Phelps SM, Lydon JP, O'malley BW, Crews D. Regulation of male sexual behavior by progesterone receptor, sexual experience, and androgen. Horm Behav. 1998 Dec; 34(3):294-302. PMID: 9878278.
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    345. Kurita T, Young P, Brody JR, Lydon JP, O'Malley BW, Cunha GR. Stromal progesterone receptors mediate the inhibitory effects of progesterone on estrogen-induced uterine epithelial cell deoxyribonucleic acid synthesis. Endocrinology. 1998 Nov; 139(11):4708-13. PMID: 9794483.
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    346. Tibbetts TA, Mendoza-Meneses M, O'Malley BW, Conneely OM. Mutual and intercompartmental regulation of estrogen receptor and progesterone receptor expression in the mouse uterus. Biol Reprod. 1998 Nov; 59(5):1143-52. PMID: 9780321.
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    347. Kurita T, Young P, Brody JR, Lydon JP, O'Malley BW, Cunha GR. Stromal Progesterone Receptors Mediate the Inhibitory Effects of Progesterone on Estrogen-Induced Uterine Epithelial Cell Deoxyribonucleic Acid Synthesis* *This work was supported by NIH Grants AG-13784 and HD-07857. Endocrinology. 1998 Nov 01; 139(11):4708-4713. PMID: 28200453.
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    348. McKenna NJ, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Distinct steady-state nuclear receptor coregulator complexes exist in vivo. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11697-702. PMID: 9751728; PMCID: PMC21703.
    349. Sivaraman L, Stephens LC, Markaverich BM, Clark JA, Krnacik S, Conneely OM, O'Malley BW, Medina D. Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats. Carcinogenesis. 1998 Sep; 19(9):1573-81. PMID: 9771927.
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    350. Jeng MH, Kao C, Sivaraman L, Krnacik S, Chung LW, Medina D, Conneely OM, O'Malley BW. Reconstitution of estrogen-dependent transcriptional activation of an adenoviral target gene in select regions of the rat mammary gland. Endocrinology. 1998 Jun; 139(6):2916-25. PMID: 9607802.
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    351. Onate SA, Boonyaratanakornkit V, Spencer TE, Tsai SY, Tsai MJ, Edwards DP, O'Malley BW. The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors. J Biol Chem. 1998 May 15; 273(20):12101-8. PMID: 9575154.
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    352. Brisken C, Park S, Vass T, Lydon JP, O'Malley BW, Weinberg RA. A paracrine role for the epithelial progesterone receptor in mammary gland development. Proc Natl Acad Sci U S A. 1998 Apr 28; 95(9):5076-81. PMID: 9560231; PMCID: PMC20216.
    353. Oligino T, Poliani PL, Wang Y, Tsai SY, O'Malley BW, Fink DJ, Glorioso JC. Drug inducible transgene expression in brain using a herpes simplex virus vector. Gene Ther. 1998 Apr; 5(4):491-6. PMID: 9614573.
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    354. Xu J, Qiu Y, DeMayo FJ, Tsai SY, Tsai MJ, O'Malley BW. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science. 1998 Mar 20; 279(5358):1922-5. PMID: 9506940.
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    355. Burcin MM, O'Malley BW, Tsai SY. A regulatory system for target gene expression. Front Biosci. 1998; 3:c1-7. PMID: 9478886.
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    356. Chappell PE, Lydon JP, Conneely OM, O'Malley BW, Levine JE. Endocrine defects in mice carrying a null mutation for the progesterone receptor gene. Endocrinology. 1997 Oct; 138(10):4147-52. PMID: 9322923.
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    357. Humphreys RC, Lydon JP, O'Malley BW, Rosen JM. Use of PRKO mice to study the role of progesterone in mammary gland development. J Mammary Gland Biol Neoplasia. 1997 Oct; 2(4):343-54. PMID: 10935022.
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    358. Spencer TE, Jenster G, Burcin MM, Allis CD, Zhou J, Mizzen CA, McKenna NJ, Onate SA, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature. 1997 Sep 11; 389(6647):194-8. PMID: 9296499.
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    359. Said TK, Conneely OM, Medina D, O'Malley BW, Lydon JP. Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo. Endocrinology. 1997 Sep; 138(9):3933-9. PMID: 9275084.
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    360. Chang KH, Chen Y, Chen TT, Chou WH, Chen PL, Ma YY, Yang-Feng TL, Leng X, Tsai MJ, O'Malley BW, Lee WH. A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9040-5. PMID: 9256431; PMCID: PMC23019.
    361. Xiang M, Gan L, Li D, Chen ZY, Zhou L, O'Malley BW, Klein W, Nathans J. Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9445-50. PMID: 9256502; PMCID: PMC23217.
    362. Jenster G, Spencer TE, Burcin MM, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor induction of gene transcription: a two-step model. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):7879-84. PMID: 9223281; PMCID: PMC21523.
    363. Shibata H, Nawaz Z, Tsai SY, O'Malley BW, Tsai MJ. Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT). Mol Endocrinol. 1997 Jun; 11(6):714-24. PMID: 9171235.
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    364. Smith CL, Nawaz Z, O'Malley BW. Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen. Mol Endocrinol. 1997 Jun; 11(6):657-66. PMID: 9171229.
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    365. Mani SK, Blaustein JD, O'Malley BW. Progesterone receptor function from a behavioral perspective. Horm Behav. 1997 Jun; 31(3):244-55. PMID: 9213138.
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    366. Humphreys RC, Lydon J, O'Malley BW, Rosen JM. Mammary gland development is mediated by both stromal and epithelial progesterone receptors. Mol Endocrinol. 1997 Jun; 11(6):801-11. PMID: 9171243.
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    367. Wang Y, Xu J, Pierson T, O'Malley BW, Tsai SY. Positive and negative regulation of gene expression in eukaryotic cells with an inducible transcriptional regulator. Gene Ther. 1997 May; 4(5):432-41. PMID: 9274720.
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    368. Bai W, Rowan BG, Allgood VE, O'Malley BW, Weigel NL. Differential phosphorylation of chicken progesterone receptor in hormone-dependent and ligand-independent activation. J Biol Chem. 1997 Apr 18; 272(16):10457-63. PMID: 9099688.
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    369. Gangolli EA, Conneely OM, O'Malley BW. Neurotransmitters activate the human estrogen receptor in a neuroblastoma cell line. J Steroid Biochem Mol Biol. 1997 Apr; 61(1-2):1-9. PMID: 9328204.
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    370. Wang Y, DeMayo FJ, Tsai SY, O'Malley BW. Ligand-inducible and liver-specific target gene expression in transgenic mice. Nat Biotechnol. 1997 Mar; 15(3):239-43. PMID: 9062922.
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    371. Allgood VE, Zhang Y, O'Malley BW, Weigel NL. Analysis of chicken progesterone receptor function and phosphorylation using an adenovirus-mediated procedure for high-efficiency DNA transfer. Biochemistry. 1997 Jan 7; 36(1):224-32. PMID: 8993337.
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    372. Shibata H, Spencer TE, Oñate SA, Jenster G, Tsai SY, Tsai MJ, O'Malley BW. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Prog Horm Res. 1997; 52:141-64; discussion 164-5. PMID: 9238851.
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    373. Wang Y, O'Malley BW, Tsai SY. Inducible system designed for future gene therapy. Methods Mol Biol. 1997; 63:401-13. PMID: 9113665.
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    374. Mani SK, Allen JM, Lydon JP, Mulac-Jericevic B, Blaustein JD, DeMayo FJ, Conneely O, O'Malley BW. Dopamine requires the unoccupied progesterone receptor to induce sexual behavior in mice. Mol Endocrinol. 1996 Dec; 10(12):1728-37. PMID: 8961281.
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    375. Apostolakis EM, Garai J, Clark JH, O'Malley BW. In vivo regulation of central nervous system progesterone receptors: cocaine induces steroid-dependent behavior through dopamine transporter modulation of D5 receptors in rats. Mol Endocrinol. 1996 Dec; 10(12):1595-604. PMID: 8961269.
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    376. Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12195-9. PMID: 8901556; PMCID: PMC37966.
    377. McInerney EM, Tsai MJ, O'Malley BW, Katzenellenbogen BS. Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator. Proc Natl Acad Sci U S A. 1996 Sep 17; 93(19):10069-73. PMID: 8816752; PMCID: PMC38337.
    378. Smith CL, Oñate SA, Tsai MJ, O'Malley BW. CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription. Proc Natl Acad Sci U S A. 1996 Aug 20; 93(17):8884-8. PMID: 8799122; PMCID: PMC38563.
    379. Apostolakis EM, Garai J, Fox C, Smith CL, Watson SJ, Clark JH, O'Malley BW. Dopaminergic regulation of progesterone receptors: brain D5 dopamine receptors mediate induction of lordosis by D1-like agonists in rats. J Neurosci. 1996 Aug 15; 16(16):4823-34. PMID: 8756415.
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    380. Katzenellenbogen JA, O'Malley BW, Katzenellenbogen BS. Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones. Mol Endocrinol. 1996 Feb; 10(2):119-31. PMID: 8825552.
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    381. Lydon JP, DeMayo FJ, Conneely OM, O'Malley BW. Reproductive phenotpes of the progesterone receptor null mutant mouse. J Steroid Biochem Mol Biol. 1996 Jan; 56(1-6 Spec No):67-77. PMID: 8603049.
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    382. Nawaz Z, Tsai MJ, O'Malley BW. Specific mutations in the ligand binding domain selectively abolish the silencing function of human thyroid hormone receptor beta. Proc Natl Acad Sci U S A. 1995 Dec 5; 92(25):11691-5. PMID: 8524830; PMCID: PMC40468.
    383. Oñate SA, Tsai SY, Tsai MJ, O'Malley BW. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science. 1995 Nov 24; 270(5240):1354-7. PMID: 7481822.
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    384. Smith CL, Conneely OM, O'Malley BW. Oestrogen receptor activation in the absence of ligand. Biochem Soc Trans. 1995 Nov; 23(4):935-9. PMID: 8654870.
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    385. Burris TP, Nawaz Z, Tsai MJ, O'Malley BW. A nuclear hormone receptor-associated protein that inhibits transactivation by the thyroid hormone and retinoic acid receptors. Proc Natl Acad Sci U S A. 1995 Oct 10; 92(21):9525-9. PMID: 7568167; PMCID: PMC40834.
    386. Lydon JP, DeMayo FJ, Funk CR, Mani SK, Hughes AR, Montgomery CA, Shyamala G, Conneely OM, O'Malley BW. Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev. 1995 Sep 15; 9(18):2266-78. PMID: 7557380.
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    387. O'Malley BW. Thirty years of steroid hormone action: personal recollections of an investigator. Steroids. 1995 Aug; 60(8):490-8. PMID: 8539790.
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    388. Mani SK, Allen JM, Clark JH, Blaustein JD, O'Malley BW. Steroid hormone--and neurotransmitter-induced rat sexual behavior: addendum. Science. 1995 Jun 30; 268(5219):1833. PMID: 7604251.
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    389. Yovandich J, O'Malley B, Sikes M, Ledley FD. Gene transfer to synovial cells by intra-articular administration of plasmid DNA. Hum Gene Ther. 1995 May; 6(5):603-10. PMID: 7578397.
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    390. Monfardini C, Kieber-Emmons T, VonFeldt JM, O'Malley B, Rosenbaum H, Godillot AP, Kaushansky K, Brown CB, Voet D, McCallus DE, et al. Recombinant antibodies in bioactive peptide design. J Biol Chem. 1995 Mar 24; 270(12):6628-38. PMID: 7896802.
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    391. Blanco JC, Wang IM, Tsai SY, Tsai MJ, O'Malley BW, Jurutka PW, Haussler MR, Ozato K. Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1535-9. PMID: 7878015; PMCID: PMC42554.
    392. Baniahmad A, Leng X, Burris TP, Tsai SY, Tsai MJ, O'Malley BW. The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing. Mol Cell Biol. 1995 Jan; 15(1):76-86. PMID: 7799971; PMCID: PMC231910.
    393. Leng X, Blanco J, Tsai SY, Ozato K, O'Malley BW, Tsai MJ. Mouse retinoid X receptor contains a separable ligand-binding and transactivation domain in its E region. Mol Cell Biol. 1995 Jan; 15(1):255-63. PMID: 7799932; PMCID: PMC231947.
    394. O'Malley BW, Schrader WT, Mani S, Smith C, Weigel NL, Conneely OM, Clark JH. An alternative ligand-independent pathway for activation of steroid receptors. Recent Prog Horm Res. 1995; 50:333-47. PMID: 7740165.
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    395. Baniahmad C, Nawaz Z, Baniahmad A, Gleeson MA, Tsai MJ, O'Malley BW. Enhancement of human estrogen receptor activity by SPT6: a potential coactivator. Mol Endocrinol. 1995 Jan; 9(1):34-43. PMID: 7760849.
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    396. Leng X, Blanco J, Tsai SY, Ozato K, O'Malley BW, Tsai MJ. Mechanisms for synergistic activation of thyroid hormone receptor and retinoid X receptor on different response elements. J Biol Chem. 1994 Dec 16; 269(50):31436-42. PMID: 7989311.
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    397. Nawaz Z, Baniahmad C, Burris TP, Stillman DJ, O'Malley BW, Tsai MJ. The yeast SIN3 gene product negatively regulates the activity of the human progesterone receptor and positively regulates the activities of GAL4 and the HAP1 activator. Mol Gen Genet. 1994 Dec 15; 245(6):724-33. PMID: 7830720.
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    398. Law SW, Apostolakis EM, Samora PJ, O'Malley BW, Clark JH. Hormonal regulation of hypothalamic gene expression: identification of multiple novel estrogen induced genes. J Steroid Biochem Mol Biol. 1994 Nov; 51(3-4):131-6. PMID: 7981121.
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    399. Mani SK, Blaustein JD, Allen JM, Law SW, O'Malley BW, Clark JH. Inhibition of rat sexual behavior by antisense oligonucleotides to the progesterone receptor. Endocrinology. 1994 Oct; 135(4):1409-14. PMID: 7925102.
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    400. Chen F, Cooney AJ, Wang Y, Law SW, O'Malley BW. Cloning of a novel orphan receptor (GCNF) expressed during germ cell development. Mol Endocrinol. 1994 Oct; 8(10):1434-44. PMID: 7854358.
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    401. Mani SK, Allen JM, Clark JH, Blaustein JD, O'Malley BW. Convergent pathways for steroid hormone- and neurotransmitter-induced rat sexual behavior. Science. 1994 Aug 26; 265(5176):1246-9. PMID: 7915049.
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    402. Wang Y, O'Malley BW, Tsai SY, O'Malley BW. A regulatory system for use in gene transfer. Proc Natl Acad Sci U S A. 1994 Aug 16; 91(17):8180-4. PMID: 8058776; PMCID: PMC44569.
    403. Mani SK, Allen JM, Rettori V, McCann SM, O'Malley BW, Clark JH. Nitric oxide mediates sexual behavior in female rats. Proc Natl Acad Sci U S A. 1994 Jul 5; 91(14):6468-72. PMID: 7517551; PMCID: PMC44223.
    404. Sikes ML, O'Malley BW, Finegold MJ, Ledley FD. In vivo gene transfer into rabbit thyroid follicular cells by direct DNA injection. Hum Gene Ther. 1994 Jul; 5(7):837-44. PMID: 7981308.
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    405. Zeng Z, Allan GF, Thaller C, Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Detection of potential ligands for nuclear receptors in cellular extracts. Endocrinology. 1994 Jul; 135(1):248-52. PMID: 8013359.
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    406. Salomonsson M, Häggblad J, O'Malley BW, Sitbon GM. The human estrogen receptor hormone binding domain dimerizes independently of ligand activation. J Steroid Biochem Mol Biol. 1994 Apr; 48(5-6):447-52. PMID: 8180105.
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    407. Baniahmad C, Baniahmad A, O'Malley BW. A rapid method combining a functional test of fusion proteins in vivo and their purification. Biotechniques. 1994 Feb; 16(2):194-6. PMID: 8179872.
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    408. Tsai MJ, O'Malley BW. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem. 1994; 63:451-86. PMID: 7979245.
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    409. Law SW, Conneely OM, O'Malley BW. Molecular cloning of a novel member of the nuclear receptor superfamily related to the orphan receptor, TR2. Gene Expr. 1994; 4(1-2):77-84. PMID: 7841789.
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    410. Leng X, Tsai SY, O'Malley BW, Tsai MJ. Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor. J Steroid Biochem Mol Biol. 1993 Dec; 46(6):643-61. PMID: 8274399.
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    411. Ray MK, Magdaleno S, O'Malley BW, DeMayo FJ. Cloning and characterization of the mouse Clara cell specific 10 kDa protein gene: comparison of the 5'-flanking region with the human rat and rabbit gene. Biochem Biophys Res Commun. 1993 Nov 30; 197(1):163-71. PMID: 7916613.
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    412. Kieback DG, Runnebaum IB, Moebus VJ, Kreienberg R, McCamant SK, Edwards CL, Jones LA, Tsai MJ, O'Malley BW. Chicken ovalbumin upstream promoter transcription factor (COUP-TF): an orphan steroid receptor with a specific pattern of differential expression in human ovarian cancer cell lines. Gynecol Oncol. 1993 Nov; 51(2):167-70. PMID: 7903949.
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    413. O'Malley BW, Ledley FD. Somatic gene therapy in otolaryngology-head and neck surgery. Arch Otolaryngol Head Neck Surg. 1993 Nov; 119(11):1191-7. PMID: 8217078.
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    414. Chen F, Law SW, O'Malley BW. Identification of two mPPAR related receptors and evidence for the existence of five subfamily members. Biochem Biophys Res Commun. 1993 Oct 29; 196(2):671-7. PMID: 8240342.
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    415. Beekman JM, Allan GF, Tsai SY, Tsai MJ, O'Malley BW. Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain. Mol Endocrinol. 1993 Oct; 7(10):1266-74. PMID: 8264659.
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    416. O'Malley BW, Ledley FD. Somatic gene therapy. Methods for the present and future. Arch Otolaryngol Head Neck Surg. 1993 Oct; 119(10):1100-7. PMID: 8398061.
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    417. Vegeto E, Shahbaz MM, Wen DX, Goldman ME, O'Malley BW, McDonnell DP. Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. Mol Endocrinol. 1993 Oct; 7(10):1244-55. PMID: 8264658.
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    418. O'Malley BW, Ledley FD. DNA- and viral-mediated gene transfer in follicular cells: progress toward gene therapy of the thyroid. Laryngoscope. 1993 Oct; 103(10):1084-92. PMID: 8412442.
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    419. Baniahmad A, Ha I, Reinberg D, Tsai S, Tsai MJ, O'Malley BW. Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone. Proc Natl Acad Sci U S A. 1993 Oct 1; 90(19):8832-6. PMID: 8415616; PMCID: PMC47454.
    420. Poletti A, Conneely OM, McDonnell DP, Schrader WT, O'Malley BW, Weigel NL. Chicken progesterone receptor expressed in Saccharomyces cerevisiae is correctly phosphorylated at all four Ser-Pro phosphorylation sites. Biochemistry. 1993 Sep 21; 32(37):9563-9. PMID: 8373763.
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    421. Smith CL, Conneely OM, O'Malley BW. Modulation of the ligand-independent activation of the human estrogen receptor by hormone and antihormone. Proc Natl Acad Sci U S A. 1993 Jul 1; 90(13):6120-4. PMID: 8327492; PMCID: PMC46879.
    422. Ing NH, Beekman JM, Kessler DJ, Murphy M, Jayaraman K, Zendegui JG, Hogan ME, O'Malley BW, Tsai MJ. In vivo transcription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotide. Nucleic Acids Res. 1993 Jun 25; 21(12):2789-96. PMID: 8332487; PMCID: PMC309654.
    423. O'Malley BW, Adams RM, Sikes ML, Sawada T, Ledley FD. Retrovirus-mediated gene transfer into canine thyroid using an ex vivo strategy. Hum Gene Ther. 1993 Apr; 4(2):171-8. PMID: 8494926.
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    424. Cooney AJ, Leng X, Tsai SY, O'Malley BW, Tsai MJ. Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors. J Biol Chem. 1993 Feb 25; 268(6):4152-60. PMID: 8382695.
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    425. O'Malley BW, Finegold MJ, Ledley FD. Autologous, orthotopic thyroid follicular cell transplantation: a surgical component of ex vivo somatic gene therapy. Otolaryngol Head Neck Surg. 1993 Jan; 108(1):51-62. PMID: 8437874.
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    426. Fuqua SA, Allred DC, Elledge RM, Krieg SL, Benedix MG, Nawaz Z, O'Malley BW, Greene GL, McGuire WL. The ER-positive/PgR-negative breast cancer phenotype is not associated with mutations within the DNA binding domain. Breast Cancer Res Treat. 1993; 26(2):191-202. PMID: 8219256.
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    427. Allan GF, Tsai SY, Tsai MJ, O'Malley BW. Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):11750-4. PMID: 1465392; PMCID: PMC50634.
    428. O'Malley BW, Sikes ML, Adams RM, Finegold MJ, Ledley FD. Somatic gene therapy targeted to the thyroid: viral-mediated gene transfer in animal models. Transplant Proc. 1992 Dec; 24(6):2973-4. PMID: 1466018.
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    429. Law SW, Conneely OM, DeMayo FJ, O'Malley BW. Identification of a new brain-specific transcription factor, NURR1. Mol Endocrinol. 1992 Dec; 6(12):2129-35. PMID: 1491694.
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    430. McDonnell DP, Vegeto E, O'Malley BW. Identification of a negative regulatory function for steroid receptors. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):10563-7. PMID: 1438251; PMCID: PMC50381.
    431. Baniahmad A, Tsai SY, O'Malley BW, Tsai MJ. Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):10633-7. PMID: 1359543; PMCID: PMC50395.
    432. Ledley FD, Soriano HE, O'Malley BW, Lewis D, Darlington GJ, Finegold M. DiI as a marker for cellular transplantation into solid organs. Biotechniques. 1992 Oct; 13(4):580, 582, 584-7. PMID: 1282342.
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    433. Allan GF, Leng X, Tsai SY, Weigel NL, Edwards DP, Tsai MJ, O'Malley BW. Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation. J Biol Chem. 1992 Sep 25; 267(27):19513-20. PMID: 1326555.
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    434. Ing NH, Beekman JM, Tsai SY, Tsai MJ, O'Malley BW. Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II). J Biol Chem. 1992 Sep 5; 267(25):17617-23. PMID: 1517211.
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    435. Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Mol Cell Biol. 1992 Sep; 12(9):4153-63. PMID: 1324415; PMCID: PMC360317.
    436. O'Malley BW, Conneely OM. Orphan receptors: in search of a unifying hypothesis for activation. Mol Endocrinol. 1992 Sep; 6(9):1359-61. PMID: 1331771.
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    437. Power RF, Conneely OM, O'Malley BW. New insights into activation of the steroid hormone receptor superfamily. Trends Pharmacol Sci. 1992 Aug; 13(8):318-23. PMID: 1413090.
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    438. Bagchi MK, Tsai MJ, O'Malley BW, Tsai SY. Analysis of the mechanism of steroid hormone receptor-dependent gene activation in cell-free systems. Endocr Rev. 1992 Aug; 13(3):525-35. PMID: 1425487.
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    439. Pham TA, Hwung YP, Santiso-Mere D, McDonnell DP, O'Malley BW. Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast. Mol Endocrinol. 1992 Jul; 6(7):1043-50. PMID: 1508220.
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    440. Vegeto E, Allan GF, Schrader WT, Tsai MJ, McDonnell DP, O'Malley BW. The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. Cell. 1992 May 15; 69(4):703-13. PMID: 1586949.
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    441. Poletti A, Weigel NL, McDonnell DP, Schrader WT, O'Malley BW, Conneely OM. A novel, highly regulated, rapidly inducible system for the expression of chicken progesterone receptor, cPRA, in Saccharomyces cerevisiae. Gene. 1992 May 1; 114(1):51-8. PMID: 1316867.
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    442. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Ligand and DNA-dependent phosphorylation of human progesterone receptor in vitro. Proc Natl Acad Sci U S A. 1992 Apr 1; 89(7):2664-8. PMID: 1557371; PMCID: PMC48722.
    443. Elliston JF, Beekman JM, Tsai SY, O'Malley BW, Tsai MJ. Hormone activation of baculovirus expressed progesterone receptors. J Biol Chem. 1992 Mar 15; 267(8):5193-8. PMID: 1544902.
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    444. Pham TA, McDonnell DP, Tsai MJ, O'Malley BW. Modulation of progesterone receptor binding to progesterone response elements by positioned nucleosomes. Biochemistry. 1992 Feb 11; 31(5):1570-8. PMID: 1737013.
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    445. O'Malley BW, Tsai MJ. Molecular pathways of steroid receptor action. Biol Reprod. 1992 Feb; 46(2):163-7. PMID: 1536890.
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    446. Fuqua SA, Fitzgerald SD, Allred DC, Elledge RM, Nawaz Z, McDonnell DP, O'Malley BW, Greene GL, McGuire WL. Inhibition of estrogen receptor action by a naturally occurring variant in human breast tumors. Cancer Res. 1992 Jan 15; 52(2):483-6. PMID: 1728420.
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    447. Conneely OM, Power RF, O'Malley BW. Regulation of gene expression by dopamine: implications in drug addiction. NIDA Res Monogr. 1992; 126:84-97. PMID: 1491719.
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    448. Nawaz Z, Tsai MJ, McDonnell DP, O'Malley BW. Identification of novel steroid-response elements. Gene Expr. 1992; 2(1):39-47. PMID: 1617301.
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    449. Weigel NL, Carter TH, Schrader WT, O'Malley BW. Chicken progesterone receptor is phosphorylated by a DNA-dependent protein kinase during in vitro transcription assays. Mol Endocrinol. 1992 Jan; 6(1):8-14. PMID: 1738374.
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    450. Power RF, Mani SK, Codina J, Conneely OM, O'Malley BW. Dopaminergic and ligand-independent activation of steroid hormone receptors. Science. 1991 Dec 13; 254(5038):1636-9. PMID: 1749936.
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    451. Leibo SP, DeMayo FJ, O'Malley B. Production of transgenic mice from cryopreserved fertilized ova. Mol Reprod Dev. 1991 Dec; 30(4):313-9. PMID: 1751035.
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    452. Schowalter DB, Sullivan WP, Maihle NJ, Dobson AD, Conneely OM, O'Malley BW, Toft DO. Characterization of progesterone receptor binding to the 90- and 70-kDa heat shock proteins. J Biol Chem. 1991 Nov 5; 266(31):21165-73. PMID: 1939158.
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    453. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70. Mol Cell Biol. 1991 Oct; 11(10):4998-5004. PMID: 1922029; PMCID: PMC361487.
    454. Pham TA, Hwung YP, McDonnell DP, O'Malley BW. Transactivation functions facilitate the disruption of chromatin structure by estrogen receptor derivatives in vivo. J Biol Chem. 1991 Sep 25; 266(27):18179-87. PMID: 1917950.
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    455. Bradshaw MS, Tsai SY, Leng XH, Dobson AD, Conneely OM, O'Malley BW, Tsai MJ. Studies on the mechanism of functional cooperativity between progesterone and estrogen receptors. J Biol Chem. 1991 Sep 5; 266(25):16684-90. PMID: 1885597.
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    456. McDonnell DP, Nawaz Z, Densmore C, Weigel NL, Pham TA, Clark JH, O'Malley BW. High level expression of biologically active estrogen receptor in Saccharomyces cerevisiae. J Steroid Biochem Mol Biol. 1991 Sep; 39(3):291-7. PMID: 1911419.
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    457. McDonnell DP, Nawaz Z, O'Malley BW. In situ distinction between steroid receptor binding and transactivation at a target gene. Mol Cell Biol. 1991 Sep; 11(9):4350-5. PMID: 1875926; PMCID: PMC361296.
    458. O'Malley B, Brown AC, Tate M, Hertzler AA, Rojas MH. Infant feeding practices of migrant farm laborers in northern Colorado. J Am Diet Assoc. 1991 Sep; 91(9):1084-7. PMID: 1918760.
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    459. Fuqua SA, Hill SM, Chamness GC, Benedix MG, Greene GL, O'Malley BW, McGuire WL. Progesterone receptor gene restriction fragment length polymorphisms in human breast tumors. J Natl Cancer Inst. 1991 Aug 21; 83(16):1157-60. PMID: 1679459.
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    460. Power RF, Lydon JP, Conneely OM, O'Malley BW. Dopamine activation of an orphan of the steroid receptor superfamily. Science. 1991 Jun 14; 252(5012):1546-8. PMID: 2047861.
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    461. Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat. J Virol. 1991 Jun; 65(6):2853-60. PMID: 2033658; PMCID: PMC240909.
    462. O'Malley BW. 13th San Antonio Breast Cancer Symposium--Plenary Lecture. Steroid hormone receptors as transactivators of gene expression. Breast Cancer Res Treat. 1991 May; 18(2):67-71. PMID: 1912609.
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    463. Pham TA, Elliston JF, Nawaz Z, McDonnell DP, Tsai MJ, O'Malley BW. Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers. Proc Natl Acad Sci U S A. 1991 Apr 15; 88(8):3125-9. PMID: 2014231; PMCID: PMC51398.
    464. Allan GF, Ing NH, Tsai SY, Srinivasan G, Weigel NL, Thompson EB, Tsai MJ, O'Malley BW. Synergism between steroid response and promoter elements during cell-free transcription. J Biol Chem. 1991 Mar 25; 266(9):5905-10. PMID: 2005127.
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    465. Allan GF, Tsai SY, O'Malley BW, Tsai MJ. Steroid hormone receptors and in vitro transcription. Bioessays. 1991 Feb; 13(2):73-8. PMID: 2029268.
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    466. O'Malley BW. Steroid hormone receptors as transactivators of gene expression. Biotechnology. 1991; 16:35-41. PMID: 1848798.
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    467. Fuqua SA, Fitzgerald SD, Chamness GC, Tandon AK, McDonnell DP, Nawaz Z, O'Malley BW, McGuire WL. Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res. 1991 Jan 1; 51(1):105-9. PMID: 1988075.
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    468. Hughes MR, Malloy PJ, O'Malley BW, Pike JW, Feldman D. Genetic defects of the 1,25-dihydroxyvitamin D3 receptor. J Recept Res. 1991; 11(1-4):699-716. PMID: 1653354.
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    469. Wang LH, Ing NH, Tsai SY, O'Malley BW, Tsai MJ. The COUP-TFs compose a family of functionally related transcription factors. Gene Expr. 1991; 1(3):207-16. PMID: 1820218.
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    470. O'Malley BW, Tsai SY, Bagchi M, Weigel NL, Schrader WT, Tsai MJ. Molecular mechanism of action of a steroid hormone receptor. Recent Prog Horm Res. 1991; 47:1-24; discussion 24-6. PMID: 1745818.
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    471. Denner LA, Weigel NL, Maxwell BL, Schrader WT, O'Malley BW. Regulation of progesterone receptor-mediated transcription by phosphorylation. Science. 1990 Dec 21; 250(4988):1740-3. PMID: 2176746.
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    472. Sone T, McDonnell DP, O'Malley BW, Pike JW. Expression of human vitamin D receptor in Saccharomyces cerevisiae. Purification, properties, and generation of polyclonal antibodies. J Biol Chem. 1990 Dec 15; 265(35):21997-2003. PMID: 2174892.
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    473. Ritchie HH, Wang LH, Tsai S, O'Malley BW, Tsai MJ. COUP-TF gene: a structure unique for the steroid/thyroid receptor superfamily. Nucleic Acids Res. 1990 Dec 11; 18(23):6857-62. PMID: 2263450; PMCID: PMC332742.
    474. Rodriguez R, Weigel NL, O'Malley BW, Schrader WT. Dimerization of the chicken progesterone receptor in vitro can occur in the absence of hormone and DNA. Mol Endocrinol. 1990 Dec; 4(12):1782-90. PMID: 2082181.
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    475. Elliston JF, Fawell SE, Klein-Hitpass L, Tsai SY, Tsai MJ, Parker MG, O'Malley BW. Mechanism of estrogen receptor-dependent transcription in a cell-free system. Mol Cell Biol. 1990 Dec; 10(12):6607-12. PMID: 2247075; PMCID: PMC362937.
    476. Tsai SY, Srinivasan G, Allan GF, Thompson EB, O'Malley BW, Tsai MJ. Recombinant human glucocorticoid receptor induces transcription of hormone response genes in vitro. J Biol Chem. 1990 Oct 5; 265(28):17055-61. PMID: 2170364.
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    477. Denner LA, Schrader WT, O'Malley BW, Weigel NL. Hormonal regulation and identification of chicken progesterone receptor phosphorylation sites. J Biol Chem. 1990 Sep 25; 265(27):16548-55. PMID: 2398063.
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    478. Elliston JF, Tsai SY, O'Malley BW, Tsai MJ. Superactive estrogen receptors. Potent activators of gene expression. J Biol Chem. 1990 Jul 15; 265(20):11517-21. PMID: 2164005.
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    479. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription. Nature. 1990 Jun 7; 345(6275):547-50. PMID: 2348863.
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    480. Carson-Jurica MA, Schrader WT, O'Malley BW. Steroid receptor family: structure and functions. Endocr Rev. 1990 May; 11(2):201-20. PMID: 2194782.
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    481. Bagchi MK, Tsai SY, Weigel NL, Tsai MJ, O'Malley BW. Regulation of in vitro transcription by progesterone receptor. Characterization and kinetic studies. J Biol Chem. 1990 Mar 25; 265(9):5129-34. PMID: 2318886.
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    482. O'Malley B. The steroid receptor superfamily: more excitement predicted for the future. Mol Endocrinol. 1990 Mar; 4(3):363-9. PMID: 2188115.
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    483. Klein-Hitpass L, Tsai SY, Weigel NL, Allan GF, Riley D, Rodriguez R, Schrader WT, Tsai MJ, O'Malley BW. The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex. Cell. 1990 Jan 26; 60(2):247-57. PMID: 2153462.
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    484. Power RF, Conneely OM, McDonnell DP, Clark JH, Butt TR, Schrader WT, O'Malley BW. High level expression of a truncated chicken progesterone receptor in Escherichia coli. J Biol Chem. 1990 Jan 25; 265(3):1419-24. PMID: 2153132.
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    485. Mak P, McDonnell DP, Weigel NL, Schrader WT, O'Malley BW. Expression of functional chicken oviduct progesterone receptors in yeast (Saccharomyces cerevisiae). J Biol Chem. 1989 Dec 25; 264(36):21613-8. PMID: 2689442.
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    486. Sone T, Scott RA, Hughes MR, Malloy PJ, Feldman D, O'Malley BW, Pike JW. Mutant vitamin D receptors which confer hereditary resistance to 1,25-dihydroxyvitamin D3 in humans are transcriptionally inactive in vitro. J Biol Chem. 1989 Dec 5; 264(34):20230-4. PMID: 2555349.
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    487. Denner LA, Weigel NL, Schrader WT, O'Malley BW. Hormone-dependent regulation of chicken progesterone receptor deoxyribonucleic acid binding and phosphorylation. Endocrinology. 1989 Dec; 125(6):3051-8. PMID: 2583054.
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    488. Ritchie HH, Hughes MR, Thompson ET, Malloy PJ, Hochberg Z, Feldman D, Pike JW, O'Malley BW. An ochre mutation in the vitamin D receptor gene causes hereditary 1,25-dihydroxyvitamin D3-resistant rickets in three families. Proc Natl Acad Sci U S A. 1989 Dec; 86(24):9783-7. PMID: 2557627; PMCID: PMC298586.
    489. Weigel NL, Schrader WT, O'Malley BW. Antibodies to chicken progesterone receptor peptide 523-536 recognize a site exposed in receptor-deoxyribonucleic acid complexes but not in receptor-heat shock protein-90 complexes. Endocrinology. 1989 Nov; 125(5):2494-501. PMID: 2791998.
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    490. Munjaal RP, Conneely OM, O'Malley BW. In situ detection of progesterone receptor mRNA in the chicken oviduct using probe-on slides. Biotechniques. 1989 Nov-Dec; 7(10):1104-8. PMID: 2629842.
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    491. O'Malley B. The power within. RNABC News. 1989 Nov-Dec; 21(6):25-6. PMID: 2602845.
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    492. Densmore CL, Markaverich BM, O'Malley BW, Clark JH. Characterization and partial purification of an estrogen type II binding site in chick oviduct cytosol. Biochemistry. 1989 Sep 19; 28(19):7788-96. PMID: 2611214.
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    493. Peleg S, Schrader WT, O'Malley BW. Differential sensitivity of chicken progesterone receptor forms to sulfhydryl reactive reagents. Biochemistry. 1989 Sep 5; 28(18):7373-9. PMID: 2819076.
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    494. O'Malley BW. Did eucaryotic steroid receptors evolve from intracrine gene regulators? Endocrinology. 1989 Sep; 125(3):1119-20. PMID: 2759020.
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    495. Conneely OM, Kettelberger DM, Tsai MJ, Schrader WT, O'Malley BW. The chicken progesterone receptor A and B isoforms are products of an alternate translation initiation event. J Biol Chem. 1989 Aug 25; 264(24):14062-4. PMID: 2760059.
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    496. Pastorcic M, Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Multiple protein binding sites within the ovalbumin gene 5'-flanking region: isolation and characterization of sequence-specific binding proteins. Nucleic Acids Res. 1989 Aug 25; 17(16):6693-711. PMID: 2780293; PMCID: PMC318360.
    497. McDonnell DP, Pike JW, Drutz DJ, Butt TR, O'Malley BW. Reconstitution of the vitamin D-responsive osteocalcin transcription unit in Saccharomyces cerevisiae. Mol Cell Biol. 1989 Aug; 9(8):3517-23. PMID: 2552296; PMCID: PMC362399.
    498. Wang LH, Tsai SY, Cook RG, Beattie WG, Tsai MJ, O'Malley BW. COUP transcription factor is a member of the steroid receptor superfamily. Nature. 1989 Jul 13; 340(6229):163-6. PMID: 2739739.
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    499. O'Malley B. Carbimazole-induced cramps. Lancet. 1989 Jun 24; 1(8652):1456-7. PMID: 2567469.
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    500. Tsai SY, Tsai MJ, O'Malley BW. Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements. Cell. 1989 May 5; 57(3):443-8. PMID: 2566384.
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    501. McDonnell DP, Scott RA, Kerner SA, O'Malley BW, Pike JW. Functional domains of the human vitamin D3 receptor regulate osteocalcin gene expression. Mol Endocrinol. 1989 Apr; 3(4):635-44. PMID: 2542779.
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    502. Dobson AD, Conneely OM, Beattie W, Maxwell BL, Mak P, Tsai MJ, Schrader WT, O'Malley BW. Mutational analysis of the chicken progesterone receptor. J Biol Chem. 1989 Mar 5; 264(7):4207-11. PMID: 2917996.
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    503. Rodriguez R, Carson MA, Weigel NL, O'Malley BW, Schrader WT. Hormone-induced changes in the in vitro DNA-binding activity of the chicken progesterone receptor. Mol Endocrinol. 1989 Feb; 3(2):356-62. PMID: 2710137.
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    504. Carson-Jurica MA, Lee AT, Dobson AW, Conneely OM, Schrader WT, O'Malley BW. Interaction of the chicken progesterone receptor with heat shock protein (HSP) 90. J Steroid Biochem. 1989; 34(1-6):1-9. PMID: 2626012.
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    505. Klein-Hitpass L, Tsai SY, Greene GL, Clark JH, Tsai MJ, O'Malley BW. Specific binding of estrogen receptor to the estrogen response element. Mol Cell Biol. 1989 Jan; 9(1):43-9. PMID: 2927397; PMCID: PMC362143.
    506. Hughes M, Malloy P, Kieback D, McDonnell D, Feldman D, Pike JW, O'Malley B. Human vitamin D receptor mutations: identification of molecular defects in hypocalcemic vitamin D resistant rickets. Adv Exp Med Biol. 1989; 255:491-503. PMID: 2618873.
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    507. Hughes MR, Malloy PJ, Kieback DG, Kesterson RA, Pike JW, Feldman D, O'Malley BW. Point mutations in the human vitamin D receptor gene associated with hypocalcemic rickets. Science. 1988 Dec 23; 242(4886):1702-5. PMID: 2849209.
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    508. Bradshaw MS, Tsai MJ, O'Malley BW. A steroid response element can function in the absence of a distal promoter. Mol Endocrinol. 1988 Dec; 2(12):1286-93. PMID: 2905764.
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    509. Bagchi MK, Elliston JF, Tsai SY, Edwards DP, Tsai MJ, O'Malley BW. Steroid hormone-dependent interaction of human progesterone receptor with its target enhancer element. Mol Endocrinol. 1988 Dec; 2(12):1221-9. PMID: 3216861.
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    510. Tsai SY, Carlstedt-Duke J, Weigel NL, Dahlman K, Gustafsson JA, Tsai MJ, O'Malley BW. Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation. Cell. 1988 Oct 21; 55(2):361-9. PMID: 3167984.
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    511. Conneely OM, Dobson AD, Carson MA, Maxwell BL, Tsai MJ, Schrader WT, O'Malley BW. Structure-function relationships of the chicken progesterone receptor. Biochem Soc Trans. 1988 Oct; 16(5):683-7. PMID: 2466711.
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    512. Komm BS, Terpening CM, Benz DJ, Graeme KA, Gallegos A, Korc M, Greene GL, O'Malley BW, Haussler MR. Estrogen binding, receptor mRNA, and biologic response in osteoblast-like osteosarcoma cells. Science. 1988 Jul 1; 241(4861):81-4. PMID: 3164526.
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    513. Bradshaw MS, Tsai MJ, O'Malley BW. A far upstream ovalbumin enhancer binds nuclear factor-1-like factor. J Biol Chem. 1988 Jun 15; 263(17):8485-90. PMID: 3372538.
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    514. Baker AR, McDonnell DP, Hughes M, Crisp TM, Mangelsdorf DJ, Haussler MR, Pike JW, Shine J, O'Malley BW. Cloning and expression of full-length cDNA encoding human vitamin D receptor. Proc Natl Acad Sci U S A. 1988 May; 85(10):3294-8. PMID: 2835767; PMCID: PMC280195.
    515. Nardulli AM, Greene GL, O'Malley BW, Katzenellenbogen BS. Regulation of progesterone receptor messenger ribonucleic acid and protein levels in MCF-7 cells by estradiol: analysis of estrogen's effect on progesterone receptor synthesis and degradation. Endocrinology. 1988 Mar; 122(3):935-44. PMID: 3342760.
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    516. Peleg S, Schrader WT, O'Malley BW. Sulfhydryl group content of chicken progesterone receptor: effect of oxidation on DNA binding activity. Biochemistry. 1988 Jan 12; 27(1):358-67. PMID: 3349038.
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    517. McDonnell DP, Pike JW, O'Malley BW. The vitamin D receptor: a primitive steroid receptor related to thyroid hormone receptor. J Steroid Biochem. 1988; 30(1-6):41-6. PMID: 2838696.
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    518. Wei LL, Krett NL, Francis MD, Gordon DF, Wood WM, O'Malley BW, Horwitz KB. Multiple human progesterone receptor messenger ribonucleic acids and their autoregulation by progestin agonists and antagonists in breast cancer cells. Mol Endocrinol. 1988 Jan; 2(1):62-72. PMID: 3398843.
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    519. Tsai MJ, Tsai SY, Klein-Hitpass L, Bagchi M, Elliston JF, Carlstedt-Duke J, Gustafsson JA, Gustafsson JK, O'Malley BW. Cooperative interactions of steroid hormone receptors with their cognate response elements. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 2:829-33. PMID: 3254786.
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    520. Wang LH, Tsai SY, Wang H, Sagami I, Tsai MJ, O'Malley BW. The studies of COUP transcription factor from HeLa cells: purification and partial characterization. Prog Clin Biol Res. 1988; 284:37-51. PMID: 3217427.
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    521. Conneely OM, Maxwell BL, Toft DO, Schrader WT, O'Malley BW. The A and B forms of the chicken progesterone receptor arise by alternate initiation of translation of a unique mRNA. Biochem Biophys Res Commun. 1987 Dec 16; 149(2):493-501. PMID: 3426587.
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    522. Huckaby CS, Conneely OM, Beattie WG, Dobson AD, Tsai MJ, O'Malley BW. Structure of the chromosomal chicken progesterone receptor gene. Proc Natl Acad Sci U S A. 1987 Dec; 84(23):8380-4. PMID: 3479797; PMCID: PMC299546.
    523. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Purification and characterization of chicken ovalbumin gene upstream promoter transcription factor from homologous oviduct cells. Mol Cell Biol. 1987 Dec; 7(12):4151-8. PMID: 3437886; PMCID: PMC368095.
    524. Wang LH, Tsai SY, Sagami I, Tsai MJ, O'Malley BW. Purification and characterization of chicken ovalbumin upstream promoter transcription factor from HeLa cells. J Biol Chem. 1987 Nov 25; 262(33):16080-6. PMID: 3680243.
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    525. Carson MA, Tsai MJ, Conneely OM, Maxwell BL, Clark JH, Dobson AD, Elbrecht A, Toft DO, Schrader WT, O'Malley BW. Structure-function properties of the chicken progesterone receptor A synthesized from complementary deoxyribonucleic acid. Mol Endocrinol. 1987 Nov; 1(11):791-801. PMID: 3153463.
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    526. Scott MJ, Tsai MJ, O'Malley BW. Deoxyribonuclease I sensitivity of the ovomucoid-ovoinhibitor gene complex in oviduct nuclei and relative location of CR1 repetitive sequences. Biochemistry. 1987 Oct 20; 26(21):6831-40. PMID: 2827735.
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    527. Tsai SY, Sagami I, Wang H, Tsai MJ, O'Malley BW. Interactions between a DNA-binding transcription factor (COUP) and a non-DNA binding factor (S300-II). Cell. 1987 Aug 28; 50(5):701-9. PMID: 3040258.
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    528. Conneely OM, Dobson AD, Tsai MJ, Beattie WG, Toft DO, Huckaby CS, Zarucki T, Schrader WT, O'Malley BW. Sequence and expression of a functional chicken progesterone receptor. Mol Endocrinol. 1987 Aug; 1(8):517-25. PMID: 3153474.
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    529. Baez M, Sargan DR, Elbrecht A, Kulomaa MS, Zarucki-Schulz T, Tsai MJ, O'Malley BW. Steroid hormone regulation of the gene encoding the chicken heat shock protein hsp 108. J Biol Chem. 1987 May 15; 262(14):6582-8. PMID: 3571271.
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    530. Law ML, Kao FT, Wei Q, Hartz JA, Greene GL, Zarucki-Schulz T, Conneely OM, Jones C, Puck TT, O'Malley BW, et al. The progesterone receptor gene maps to human chromosome band 11q13, the site of the mammary oncogene int-2. Proc Natl Acad Sci U S A. 1987 May; 84(9):2877-81. PMID: 3472240; PMCID: PMC304763.
    531. Scott MJ, Huckaby CS, Kato I, Kohr WJ, Laskowski M, Tsai MJ, O'Malley BW. Ovoinhibitor introns specify functional domains as in the related and linked ovomucoid gene. J Biol Chem. 1987 Apr 25; 262(12):5899-907. PMID: 3571241.
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    532. Gope ML, Keinänen RA, Kristo PA, Conneely OM, Beattie WG, Zarucki-Schulz T, O'Malley BW, Kulomaa MS. Molecular cloning of the chicken avidin cDNA. Nucleic Acids Res. 1987 Apr 24; 15(8):3595-606. PMID: 3575102; PMCID: PMC340752.
    533. McDonnell DP, Mangelsdorf DJ, Pike JW, Haussler MR, O'Malley BW. Molecular cloning of complementary DNA encoding the avian receptor for vitamin D. Science. 1987 Mar 6; 235(4793):1214-7. PMID: 3029866.
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    534. Denner LA, Weigel NL, Schrader WT, O'Malley BW. High-yield high-performance liquid chromatographic analysis of steroid hormone receptors on glass columns. Anal Biochem. 1987 Mar; 161(2):291-9. PMID: 3578794.
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    535. Elbrecht A, DeMayo FJ, Tsai MJ, O'Malley BW. Episomal maintenance of a bovine papilloma virus vector in transgenic mice. Mol Cell Biol. 1987 Mar; 7(3):1276-9. PMID: 3031486; PMCID: PMC365203.
    536. Birnbaumer M, Hinrichs-Rosello MV, Cook RG, Schrader WT, O'Malley BW. Chemical and antigenic properties of pure 108,000 molecular weight chick progesterone receptor. Mol Endocrinol. 1987 Mar; 1(3):249-59. PMID: 3453892.
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    537. Maxwell BL, McDonnell DP, Conneely OM, Schulz TZ, Greene GL, O'Malley BW. Structural organization and regulation of the chicken estrogen receptor. Mol Endocrinol. 1987 Jan; 1(1):25-35. PMID: 2901032.
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    538. Kleinsek DA, Beattie WG, Tsai MJ, O'Malley BW. Molecular cloning of a steroid-regulated 108K heat shock protein gene from hen oviduct. Nucleic Acids Res. 1986 Dec 22; 14(24):10053-69. PMID: 3027654; PMCID: PMC341355.
    539. Sagami I, Tsai SY, Wang H, Tsai MJ, O'Malley BW. Identification of two factors required for transcription of the ovalbumin gene. Mol Cell Biol. 1986 Dec; 6(12):4259-67. PMID: 3796602; PMCID: PMC367207.
    540. Kulomaa MS, Weigel NL, Kleinsek DA, Beattie WG, Conneely OM, March C, Zarucki-Schulz T, Schrader WT, O'Malley BW. Amino acid sequence of a chicken heat shock protein derived from the complementary DNA nucleotide sequence. Biochemistry. 1986 Oct 7; 25(20):6244-51. PMID: 3024703.
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    541. Sargan DR, Tsai MJ, O'Malley BW. hsp108,,,,,, a novel heat shock inducible protein of chicken. Biochemistry. 1986 Oct 7; 25(20):6252-8. PMID: 3098286.
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    542. Conneely OM, Sullivan WP, Toft DO, Birnbaumer M, Cook RG, Maxwell BL, Zarucki-Schulz T, Greene GL, Schrader WT, O'Malley BW. Molecular cloning of the chicken progesterone receptor. Science. 1986 Aug 15; 233(4765):767-70. PMID: 2426779.
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    543. Pastorcic M, Wang H, Elbrecht A, Tsai SY, Tsai MJ, O'Malley BW. Control of transcription initiation in vitro requires binding of a transcription factor to the distal promoter of the ovalbumin gene. Mol Cell Biol. 1986 Aug; 6(8):2784-91. PMID: 3785213; PMCID: PMC367845.
    544. Grody WW, Schrader WT, O'Malley BW. Reversible dissociation of chick oviduct progesterone receptor subunits. Adv Exp Med Biol. 1986; 205:351-71. PMID: 3788718.
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    545. Comptom JG, Schrader WT, O'Malley BW. Progesterone receptor interaction in the 5'-flanking regulatory region of the ovalbumin gene. Adv Exp Med Biol. 1986; 196:291-304. PMID: 3716923.
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    546. O'Malley BW, Schrader WT, Tsai MJ. Molecular actions of steroid hormones. Adv Exp Med Biol. 1986; 196:1-10. PMID: 3012973.
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    547. Peleg S, Schrader WT, Edwards DP, McGuire WL, O'Malley BW. Immunologic detection of a protein homologous to chicken progesterone receptor B subunit. J Biol Chem. 1985 Jul 15; 260(14):8492-501. PMID: 2409088.
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    548. Elbrecht A, Tsai SY, Tsai MJ, O'Malley BW. Identification by exonuclease footprinting of a distal promoter-binding protein from HeLa cell extracts. DNA. 1985 Jun; 4(3):233-40. PMID: 2988892.
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    549. Sanzo M, Stevens B, Tsai MJ, O'Malley BW. Isolation of a protein fraction that binds preferentially to chicken middle repetitive DNA. Biochemistry. 1984 Dec 18; 23(26):6491-8. PMID: 6543321.
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    550. Stumph WE, Hodgson CP, Tsai MJ, O'Malley BW. Genomic structure and possible retroviral origin of the chicken CR1 repetitive DNA sequence family. Proc Natl Acad Sci U S A. 1984 Nov; 81(21):6667-71. PMID: 6593723; PMCID: PMC391991.
    551. Simmen FA, Gope ML, Schulz TZ, Wright DA, Carpenter G, O'Malley BW. Isolation of an evolutionarily conserved epidermal growth factor receptor cDNA from human A431 carcinoma cells. Biochem Biophys Res Commun. 1984 Oct 15; 124(1):125-32. PMID: 6093780.
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    552. Simmen FA, Schulz TZ, Headon DR, Wright DA, Carpenter G, O'Malley BW. Translation in Xenopus oocytes of messenger RNA from A431 cells for human epidermal growth factor receptor proteins. DNA. 1984 Oct; 3(5):393-9. PMID: 6096098.
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    553. Zarucki-Schulz T, Kulomaa MS, Headon DR, Weigel NL, Baez M, Edwards DP, McGuire WL, Schrader WT, O'Malley BW. Molecular cloning of a cDNA for the chicken progesterone receptor B antigen. Proc Natl Acad Sci U S A. 1984 Oct; 81(20):6358-62. PMID: 6593705; PMCID: PMC391923.
    554. Tsai SY, Dicker P, Fang P, Tsai MJ, O'Malley BW. Generation of monoclonal antibodies to RNA polymerase II for the identification of transcriptional factors. J Biol Chem. 1984 Sep 25; 259(18):11587-93. PMID: 6381502.
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    670. Socher SH, Krall JF, Jaffe RC, O'Malley BW. Distribution binding sites for the progesterone receptor within chick oviduct chromatin. Endocrinology. 1976 Sep; 99(3):891-900. PMID: 182471.
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    671. Tsai SY, Harris SE, Tsai MJ, O'Malley BW. Effects of estrogen on gene expression in chick oviduct. The role of chromatin proteins in regulating transcription of the ovalbumin gene. J Biol Chem. 1976 Aug 10; 251(15):4713-21. PMID: 947905.
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    672. Chan L, Jackson RL, O'Malley BW, Means AR. Synthesis of very low density lipoproteins in the cockerel. Effects of estrogen. J Clin Invest. 1976 Aug; 58(2):368-79. PMID: 182719; PMCID: PMC333192.
    673. Strätling WH, O'Malley BW. Studies on the structure and function of chick-oviduct chromatin. 2. Biochemical characterization of two chromatin fractions isolated by ECTHAM-cellulose chromatography. Eur J Biochem. 1976 Jul 15; 66(3):435-41. PMID: 182491.
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    675. Woo SL, Smith RG, Means AR, O'Malley BW. The ovalbumin gene. Partial purification of the coding strand. J Biol Chem. 1976 Jul 10; 251(13):3868-74. PMID: 932010.
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    676. Sperry PJ, Woo SL, Means AR, O'Malley BW. Partial purification of a progesterone-inducible messenger RNA (avidin) from hen oviduct. Endocrinology. 1976 Jul; 99(1):315-25. PMID: 939199.
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    677. Monahan JJ, Harris SE, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. Effect of estrogen on the sequence and population complexity of chick oviduct poly(A)-containing RNA. J Biol Chem. 1976 Jun 25; 251(12):3738-48. PMID: 932004.
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    678. Chan L, O'Malley BW. Mechanism of action of the sex steroid hormones (third of three parts). N Engl J Med. 1976 Jun 24; 294(26):1430-7. PMID: 58379.
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    679. Chan L, O'Malley BW. Mechanism of action of the sex steroid hormones (second of three parts). N Engl J Med. 1976 Jun 17; 294(25):1372-81. PMID: 177874.
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    680. Chan L, O'Malley BW. Mechanism of action of the sex steroid hormones (first of three parts). N Engl J Med. 1976 Jun 10; 294(24):1322-8. PMID: 177871.
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    681. Van NT, Holder JW, Woo SL, Means AR, O'Malley BW. Secondary structure of ovalbumin messenger RNA. Biochemistry. 1976 May 18; 15(10):2054-62. PMID: 1276125.
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    682. Keller RK, Chandra T, Schrader WT, O'Malley BW. Protein kinases of the chick oviduct: a study of the cytoplasmic and nuclear enzymes. Biochemistry. 1976 May 4; 15(9):1958-67. PMID: 1268202.
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    683. Tsai MJ, Towle TC, Harris SE, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. J Biol Chem. 1976 Apr 10; 251(7):1960-8. PMID: 773931.
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    684. Buller RE, Schwartz RJ, O'Malley BW. Steroid hormone receptor fraction stimulation of RNA synthesis: a caution. Biochem Biophys Res Commun. 1976 Mar 8; 69(1):106-13. PMID: 177017.
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    685. Chan L, Kohler PO, O'Malley BW. Translation of ovalbumin mRNA in Xenopus laevis oocytes. Characterization of the system and effects of estrogen on injected mRNA populations. J Clin Invest. 1976 Mar; 57(3):576-85. PMID: 765353; PMCID: PMC436690.
    686. Hirose M, Tsai MJ, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. Kinetics of initiation of in vitro transcription on chromatin. J Biol Chem. 1976 Feb 25; 251(4):1137-46. PMID: 765337.
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    687. O'Malley BW, Schrader WT. The receptors of steroid hormones. Sci Am. 1976 Feb; 234(2):32-43. PMID: 174193.
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    688. Harris SE, Schwartz RJ, Tsai MJ, O'Malley BW, Roy AK. Effect of estrogen on gene expression in the chick oviduct. In vitro transcription of the ovalbumin gene in chromatin. J Biol Chem. 1976 Jan 25; 251(2):524-9. PMID: 1245487.
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    689. Kalimi M, Tsai SY, Tsai MJ, Clark JH, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. Correlation between nuclear-bound estrogen receptor and chromatin initiation site for transcription. J Biol Chem. 1976 Jan 25; 251(2):516-23. PMID: 173720.
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    690. Monahan JJ, Harris SE, Woo SL, Robberson DL, O'Malley BW. The synthesis and properties of the complete complementary DNA transcript of ovalbumin mRNA. Biochemistry. 1976 Jan 13; 15(1):223-33. PMID: 55272.
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    691. Schrader WT, Schwartz RJ, Kuhn RW, Buller RE, O'Malley BW. Progesterone-receptor mediation of chromatin RNA transcription in a cell-free system. J Toxicol Environ Health Suppl. 1976; 1:77-96. PMID: 1078524.
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    692. Buller RE, O'Malley BW. The biology and mechanism of steroid hormone receptor interaction with the eukaryotic nucleus. Biochem Pharmacol. 1976 Jan; 25(1):1-12. PMID: 175801.
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    693. O'Malley BW, Means AR. The mechanism of steroid-hormone regulation of transcription of specific eukaryotic genes. Prog Nucleic Acid Res Mol Biol. 1976; 19:403-19. PMID: 798241.
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    694. O'Malley BW. Steroid hormone regulation of gene expression. Adv Pathobiol. 1976; 2:34-7. PMID: 1023762.
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    695. Towle HC, Tsai MJ, Hirose M, Tsai SY, Schwartz RJ, Parker MG, O'Malley BW. Regulation of transcription of the eucaryotic genome. Symp Soc Dev Biol. 1976; (34):107-36. PMID: 798339.
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    696. Krall JF, Socher SH, Van NT, O'Malley BW. Fractionation of chick oviduct chromatin. Nuclease-resistant deoxyribonucleic acid. Biochem J. 1975 Dec; 151(3):497-503. PMID: 1240757; PMCID: PMC1172396.
    697. Tsai SY, Tsai MJ, Schwartz R, Kalimi M, Clark JH, O'Malley BW. Effects of estrogen on gene expression in chick oviduct: nuclear receptor levels and initiation of transcription. Proc Natl Acad Sci U S A. 1975 Nov; 72(11):4228-32. PMID: 172899; PMCID: PMC388693.
    698. Woo SL, O'Malley BW. Hormone inducible messenger RNA. Life Sci. 1975 Oct 10; 17(7):1039-47. PMID: 1105042.
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    699. Keller RK, Socher SH, Krall JF, Chandra T, O'Malley BW. Fractionation of chick oviduct chromatin: IV. Association of protein kinase with transcriptionally active chromatin. Biochem Biophys Res Commun. 1975 Sep 16; 66(2):453-9. PMID: 1101886.
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    700. Jaffe RC, Socher SH, O'Malley BW. An analysis of the binding of the chick oviduct progesterone-receptor to chromatin. Biochim Biophys Acta. 1975 Aug 13; 399(2):403-19. PMID: 169905.
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    701. Schwartz RJ. Effect of estrogen on gene expression in the chick oviduct. V. Changes in the number of RNA polymerase binding and initiation sites in chromatin. J Biol Chem. 1975 Jul 10; 250(13):5175-82. PMID: 1097440.
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    702. Effects of estrogen on gene expression in the chick oviduct. IV. Initiation of RNA synthesis on DNA and chromatin. J Biol Chem. 1975 Jul 10; 250(13):5165-74. PMID: 1097439.
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    703. Rosen JM, Chan L, Woo SL, Harris SE, Means AR, O'Malley BW. Effect of estrogen on the synthesis and processing of ovalbumin messenger RNA in the chick oviduct. Brookhaven Symp Biol. 1975 Jul; (26):320-32. PMID: 1192242.
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    704. Kuhn RW, Schrader WT, Smith RG, O'Malley BW. Progesterone binding components of chick oviduct. X. Purification by affinity chromatography. J Biol Chem. 1975 Jun 10; 250(11):4220-8. PMID: 165193.
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    705. Harris SE, Rosen JM, Means AR, O'Malley BW. Use of a specific probe for ovalbumin messenger RNA to quantitate estrogen-induced gene transcripts. Biochemistry. 1975 May 20; 14(10):2072-81. PMID: 50081.
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    706. Conn PM, O'Malley B. Lysozyme (muramidase) in isolated chick oviduct nuclei. Biochem Biophys Res Commun. 1975 May 19; 64(2):740-6. PMID: 1147952.
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    707. Means AR, Woo S, Harris SE, O'Malley BW. Estrogen induction of ovalbumin mRNA: evidence for transcription control. Mol Cell Biochem. 1975 Apr 30; 7(1):33-42. PMID: 1094273.
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    708. Buller RE, Toft DO, Schrader WT, O'Malley BW. Progesterone-binding components of chick oviduct. VIII. Receptor activation and hormone-dependent binding to purified nuclei. J Biol Chem. 1975 Feb 10; 250(3):801-8. PMID: 163239.
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    709. Buller RE, Schrader WT, O'Malley BW. Progesterone-binding components of chick oviduct. IX. The kinetics of nuclear binding. J Biol Chem. 1975 Feb 10; 250(3):809-18. PMID: 163240.
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    710. Schrader WT, Heuer SS, O'Malley BW. Progesterone receptors of chick oviduct: identification of 6S receptor dimers. Biol Reprod. 1975 Feb; 12(1):134-42. PMID: 166713.
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    711. Smith RG, Iramain CA, Buttram VC, O'Malley BW. Purification of human uterine progesterone receptor. Nature. 1975 Jan 24; 253(5489):271-2. PMID: 163440.
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    712. Rosen JM, Woo SL, Holder JW, Means AR, O'Malley BW. Preparation and preliminary characterization of purified ovalbumin messenger RNA from the hen oviduct. Biochemistry. 1975 Jan 14; 14(1):69-78. PMID: 1109593.
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    713. Smith HE, Smith RG, Toft DO, Neergaard JR, Burrows EP, O'Malley BW. Binding of steroids to progesterone receptor proteins in chick oviduct and human uterus. J Biol Chem. 1974 Sep 25; 249(18):5924-32. PMID: 4369808.
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    714. Rosen JM, Harris SE, Rosenfeld GC, Liarakos CD, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. 3. Hybridization studies with (3H) messenger RNA and (3H) complementary DNA under conditions of DNA excess. Cell Differ. 1974 Jul; 3(2):103-16. PMID: 4136693.
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    715. Leavitt WW, Toft DO, Strott CA, O'Malley BW. A specific progesterone receptor in the hamster uterus: physiologic properties and regulation during the estrous cycle. Endocrinology. 1974 Apr; 94(4):1041-53. PMID: 4362041.
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    716. O'Malley BW, Means AR. Female steroid hormones and target cell nuclei. Science. 1974 Feb 15; 183(4125):610-20. PMID: 4359082.
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    717. Woo SL, Harris SE, Rosen JM, Chan L, Sperry PJ, Means AR, O'Malley BW. Use of Sepharose 4B for preparative scale fractionation of eukaryotic messenger RNA's. Prep Biochem. 1974; 4(6):555-72. PMID: 4475423.
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    718. O'Malley BW, Means AR, Socher SH, Spelsberg TC, Chytil F, Comstock JP, Mitchell WM. Hormonal control of oviduct growth and differentiation. Symp Soc Dev Biol. 1974; 30(0):53-77. PMID: 4276099.
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    719. Harris SE, Means AR, Mitchell WM, O'Malley BW. Synthesis of (3H)DNA complementary to ovalbumin messenger RNA: evidence for limited copies of the ovalbumin gene in chick oviduct. Proc Natl Acad Sci U S A. 1973 Dec; 70(12):3776-80. PMID: 4129926; PMCID: PMC427326.
    720. Spelsberg TC, Mitchell WM, Chytil F, Wilson EM, O'Malley BW. Chromatin of the developing chick oviduct: changes in the acidic proteins. Biochim Biophys Acta. 1973 Jul 27; 312(4):765-78. PMID: 4741145.
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    721. Liarakos CD, Rosen JM, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. II. Transcription of chick tritiated unique deoxyribonucleic acid as measured by hybridization in ribonucleic acid excess. Biochemistry. 1973 Jul 17; 12(15):2809-16. PMID: 4719120.
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    722. Rosen JM, Liarakos CD, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. I. Deoxyribonucleic acid--deoxyribonucleic acid renaturation studies. Biochemistry. 1973 Jul 17; 12(15):2803-9. PMID: 4719119.
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    723. Chan L, Means AR, O'Malley BW. Rates of induction of specific translatable messenger RNAs for ovalbumin and avidin by steroid hormones. Proc Natl Acad Sci U S A. 1973 Jun; 70(6):1870-4. PMID: 4515943; PMCID: PMC433615.
    724. O'Malley BW, Schrader WT, Spelsberg TC. Hormone-receptor interactions with the genome of eucaryotic target cells. Adv Exp Med Biol. 1973; 36(0):174-96. PMID: 4368779.
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    725. O'Malley BW, Rosenfeld GC, Comstock JP, Means AR. Steroid hormone induction of a specific translatable messenger RNA. Nat New Biol. 1972 Nov 8; 240(97):45-8. PMID: 4508393.
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    726. Feil PD, Glasser SR, Toft DO, O'Malley BW. Progesterone binding in the mouse and rat uterus. Endocrinology. 1972 Sep; 91(3):738-46. PMID: 5041206.
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    727. Comstock JP, Rosenfeld GC, O'Malley BW, Means AR. Estrogen-induced changes in translation, and specific messenger RNA levels during oviduct differentiation. Proc Natl Acad Sci U S A. 1972 Sep; 69(9):2377-80. PMID: 4506757; PMCID: PMC426944.
    728. Means AR, Comstock JP, Rosenfeld GC, O'Malley BW. Ovalbumin messenger RNA of chick oviduct: partial characterization, estrogen dependence, and translation in vitro. Proc Natl Acad Sci U S A. 1972 May; 69(5):1146-50. PMID: 4504328; PMCID: PMC426650.
    729. Rosenfeld GC, Comstock JP, Means AR, O'Malley BW. A rapid method for the isolation and partial purification of specific eucaryotic messenger RNA's. Biochem Biophys Res Commun. 1972 Apr 28; 47(2):387-92. PMID: 4662399.
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    730. Schrader WT, Toft DO, O'Malley BW. Progesterone-binding protein of chick oviduct. VI. Interaction of purified progesterone-receptor components with nuclear constituents. J Biol Chem. 1972 Apr 25; 247(8):2401-7. PMID: 5019955.
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    731. O'Malley BW, Schrader WT. Progesterone receptor components: identification of subunits binding to the target-cell genome. J Steroid Biochem. 1972 Apr; 3(3):617-29. PMID: 4343494.
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    732. Toft D, O'Malley BW. Target tissue receptors for progesterone: the influence of estrogen treatment. Endocrinology. 1972 Apr; 90(4):1041-5. PMID: 5011045.
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    733. Means AR, O'Malley BW. Mechanism of estrogen action: early transcriptional and translational events. Metabolism. 1972 Apr; 21(4):357-70. PMID: 4551383.
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    734. Spelsberg TC, Steggles AW, Chytil F, O'Malley BW. Progesterone-binding components of chick oviduct. V. Exchange of progesterone-binding capacity from target to nontarget tissue chromatins. J Biol Chem. 1972 Mar 10; 247(5):1368-74. PMID: 5012312.
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    735. Rosenfeld GC, Comstock JP, Means AR, O'Malley BW. Estrogen-induced synthesis of ovalbumin messenger RNA and its translation in a cell-free system. Biochem Biophys Res Commun. 1972 Feb 25; 46(4):1695-703. PMID: 5015606.
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    736. Comstock JP, O'Malley BW, Means AR. Stimulation of cell-free polypeptide synthesis by a protein fraction extracted from chick oviduct polyribosomes. Biochemistry. 1972 Feb 15; 11(4):646-52. PMID: 4622202.
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    737. O'Malley BW, Spelsberg TC, Scharder WT, Chytil F, Steggles AW. Mechanisms of interaction of a hormone--receptor complex with the genome of a eukaryotic target cell. Nature. 1972 Jan 21; 235(5334):141-4. PMID: 4551223.
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    738. Schrader WT, O'Malley BW. Progesterone-binding components of chick oviduct. IV. Characterization of purified subunits. J Biol Chem. 1972 Jan 10; 247(1):51-9. PMID: 5017767.
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    739. O'Malley BW, Rosenfeld GC, Comstock JP, Means AR. Induction of specific translatable messenger RNA's by oestrogen and progesterone. Acta Endocrinol Suppl (Copenh). 1972; 168:381-95. PMID: 4538753.
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    740. Spelsberg TC, Steggles AW, O'Malley B. Changes in chromatin composition and hormone binding during chick oviduct development. Biochim Biophys Acta. 1971 Nov 29; 254(1):129-34. PMID: 5134204.
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    741. Means AR, Comstock JP, O'Malley BW. Isolation of protein factors from oviduct polysomes which stimulate protein synthesis. Biochem Biophys Res Commun. 1971 Nov 5; 45(3):759-66. PMID: 5128183.
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    742. O'Malley BW. Unified hypothesis for early biochemical sequence of events in steroid hormone action. Metabolism. 1971 Oct; 20(10):981-8. PMID: 5097685.
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    743. Spelsberg TC, Steggles AW, O'Malley BW. Progesterone-binding components of chick oviduct. 3. Chromatin acceptor sites. J Biol Chem. 1971 Jul 10; 246(13):4188-97. PMID: 5559842.
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    744. Steggles AW, Spelsberg TC, Glasser SR, O'Malley BW. Soluble complexes between steroid hormones and target-tissue receptors bind specifically to target-tissue chromatin. Proc Natl Acad Sci U S A. 1971 Jul; 68(7):1479-82. PMID: 5283938; PMCID: PMC389222.
    745. Leung BS, Means AR, O'Malley BW. Effect of cyclic adenosine 3',5'-monophosphate on the incorporation of 3H-leucine into polypeptides by beef thyroid polysomes in vitro. Endocrinology. 1971 Jul; 89(1):70-8. PMID: 4325211.
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    746. Means AR, Abrass IB, O'Malley BW. Protein biosynthesis on chick oviduct polyribosomes. I. Changes during estrogen-mediated tissue differentiation. Biochemistry. 1971 Apr 27; 10(9):1561-70. PMID: 4931748.
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    747. Means AR, O'Malley BW. Protein biosynthesis on chick oviduct polyribosomes. II. Regulation by progesterone. Biochemistry. 1971 Apr 27; 10(9):1570-6. PMID: 5580670.
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    748. Steggles AW, Spelsberg TC, O'Malley BW. Tissue specific binding in vitro of progesterone-receptor to the chromatins of chick tissues. Biochem Biophys Res Commun. 1971 Apr 2; 43(1):20-7. PMID: 5579944.
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    749. O'Malley BW, Toft DO, Sherman MR. Progesterone-binding components of chick oviduct. II. Nuclear components. J Biol Chem. 1971 Feb 25; 246(4):1117-22. PMID: 5543677.
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    750. O'Malley BW. Mechanisms of action of steroid hormones. N Engl J Med. 1971 Feb 18; 284(7):370-7. PMID: 4924340.
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    751. Means AR, O'Malley BW. Assessment of sex steroid action in vitro. Acta Endocrinol Suppl (Copenh). 1971; 153:318-36. PMID: 5314239.
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    752. Sherman MR, Corvol PL, O'Malley BW. Progesterone-binding components of chick oviduct. I. Preliminary characterization of cytoplasmic components. J Biol Chem. 1970 Nov 25; 245(22):6085-96. PMID: 5484467.
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    753. Cohen S, O'Malley BW, Stastny M. Estrogenic induction of ornithine decarboxylase in vivo and in vitro. Science. 1970 Oct 16; 170(3955):336-8. PMID: 5460039.
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    754. O'Malley BW, Sherman MR, Toft DO. Progesterone "receptors" in the cytoplasm and nucleus of chick oviduct target tissue. Proc Natl Acad Sci U S A. 1970 Oct; 67(2):501-8. PMID: 5289005; PMCID: PMC283235.
    755. Kissel JH, Rosenfeld MG, Chase LR, O'Malley BW. Response of chick oviduct adenyl cyclase to steroid hormones. Endocrinology. 1970 May; 86(5):1019-23. PMID: 4314065.
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    756. Rosenfeld MG, O'Malley BW. Steroid hormones: effects on adenyl cyclase activity and adenosine 3',5'-momophosphate in target tissues. Science. 1970 Apr 10; 168(3928):253-5. PMID: 4313907.
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    757. O'Malley BW. Hormonal regulation of nucleic acid and protein synthesis. Trans N Y Acad Sci. 1969 May; 31(5):478-503. PMID: 4307379.
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    758. Dingman CW, Aronow A, Bunting SL, Peacock AC, O'Malley BW. Changes in chick oviduct ribonucleic acid following hormonal stimulation. Biochemistry. 1969 Feb; 8(2):489-95. PMID: 5793704.
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    759. O'Malley BW, McGuire WL. Progesterone-induced synthesis of a new species of nuclear RNA. Endocrinology. 1969 Jan; 84(1):63-8. PMID: 5782587.
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    760. O'Malley BW, McGuire WL, Kohler PO, Korenman SG. Studies on the mechanism of steroid hormone regulation of synthesis of specific proteins. Recent Prog Horm Res. 1969; 25:105-60. PMID: 4902947.
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    761. Kohler PO, Grimley PM, O'Malley BW. Estrogen-induced cytodifferentiation of the ovalbumin-secreting glands of the chick oviduct. J Cell Biol. 1969 Jan; 40(1):8-27. PMID: 5782453; PMCID: PMC2107600.
    762. O'Malley BW, Kohler PO. Hypoparathyroidism. Postgrad Med. 1968 Dec; 44(6):77-81 concl. PMID: 5726981.
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    763. O'Malley BW, Kohler PO. Hypoparathyroidism. 2. Postgrad Med. 1968 Nov; 44(5):182-6. PMID: 5714855.
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    764. O'Malley BW, Aronow A, Peacock AC, Dingman CW. Estrogen-dependent increase in transfer RNA during differentiation of the chick oviduct. Science. 1968 Nov 1; 162(3853):567-8. PMID: 5706938.
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    765. O'Malley BW, Kohler PO. Hypoparathyroidism. I. Postgrad Med. 1968 Oct; 44(4):71-5. PMID: 5682612.
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    766. O'Malley BW, McGuire WL. Changes in hybridizable nuclear RNA during progesterone induction of a specific oviduct protein. Biochem Biophys Res Commun. 1968 Aug 21; 32(4):595-8. PMID: 5682282.
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    767. O'Malley BW, McGuire WL. Studies on the mechanism of estrogen-mediated tissue differentiation: regulation of nuclear transcription and induction of new RNA species. Proc Natl Acad Sci U S A. 1968 Aug; 60(4):1527-34. PMID: 5244758; PMCID: PMC224950.
    768. Korenman SG, O'Malley BW. Progesterone action: regulation of avidin biosynthesis by hen oviduct in vivo and in vitro. Endocrinology. 1968 Jul; 83(1):11-7. PMID: 5659423.
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    769. O'Malley BW, McGuire WL, Middleton PA. Altered gene expression during differentiation: population changes in hybridizable RNA after stimulation of the chick oviduct with oestrogen. Nature. 1968 Jun 29; 218(5148):1249-51. PMID: 5656650.
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    770. Kohler PO, Grimley PM, O'Malley BW. Protein synthesis: differential stimulation of cell-specific proteins in epithelial cells of chick oviduct. Science. 1968 Apr 5; 160(3823):86-7. PMID: 4868141.
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    771. McGuire WL, O'Malley BW. Ribonucleic acid polymerase activity of the chick oviduct during steroid-induced synthesis of a specific protein. Biochim Biophys Acta. 1968 Mar 18; 157(1):187-94. PMID: 5689424.
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    772. O'Malley BW, McGuire WL. Studies on the mechanism of action of progesterone in regulation of the synthesis of specific protein. J Clin Invest. 1968 Mar; 47(3):654-64. PMID: 5637149; PMCID: PMC297211.
    773. O'Malley BW, Kirschner MA, Bardin CW. Estimation of plasma androgenic and progestational steroids in the laying hen. Proc Soc Exp Biol Med. 1968 Feb; 127(2):521-3. PMID: 5645041.
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    774. O'Malley BW, Kohler PO. Studies on steroid regulation of synthesis of a specific oviduct protein in a new monolayer culture system. Proc Natl Acad Sci U S A. 1967 Dec; 58(6):2359-66. PMID: 5242212; PMCID: PMC223843.
    775. Kohler PO, O'Malley BW. Estrogen-induced morphologic changes in monolayer cultures of immature chick oviduct. Endocrinology. 1967 Dec; 81(6):1422-7. PMID: 6080095.
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    776. Kulin HE, Kohler PO, O'Malley BW, Odell WD. Thyroid-stimulating hormone in thyroid dysgenesis. J Pediatr. 1967 Nov; 71(5):714-7. PMID: 4168021.
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    777. O'Malley BW, Korenman SG. Studies on the mechanism of hormone induction of a specific protein. Immunological identity and kinetic studies of avidin synthesized in vitro by the chick oviduct. Life Sci. 1967 Sep 15; 6(18):1953-9. PMID: 6052688.
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    778. O'Malley BW, McGuire WL, Middleton PA. Structure-function relationships of various steroids relative to induction of a specific oviduct protein (Avidin). Endocrinology. 1967 Sep; 81(3):677-8. PMID: 6033202.
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    780. O'Malley BW. In vitro hormonal induction of a specific protein (avidin) in chick oviduct. Biochemistry. 1967 Aug; 6(8):2546-51. PMID: 6058123.
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    781. O'Malley BW, Kohler PO. Hormonal induction of specific proteins in chick oviduct cell cultures. Biochem Biophys Res Commun. 1967 Jul 10; 28(1):1-7. PMID: 6049847.
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    782. O'Malley BW, Lipsett MB, Jackson MA. Steroid content and synthesis in a virilizing luteoma. J Clin Endocrinol Metab. 1967 Mar; 27(3):311-9. PMID: 4290318.
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    783. O'Malley BW, Mengel CE. Effects of in vivo hyperoxia on erythrocytes. V. Changes of RBC glycolytic intermediates in mice after in vivo oxygen under high pressure. Blood. 1967 Feb; 29(2):196-202. PMID: 4381497.
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    784. Kohler PO, O'Malley BW, Rayford PL, Lipsett MB, Odell WD. Effect of pyrogen on blood levels of pituitary trophic hormones. Observations of the usefulness of the growth hormone response in the detection of pituitary disease. J Clin Endocrinol Metab. 1967 Feb; 27(2):219-26. PMID: 6018576.
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    785. O'Malley BW, Lipsett MB. Urinary ketosteroids in the rhesus monkey. Steroids. 1966 Nov; 8(5):711-8. PMID: 4986630.
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    786. O'Malley BW, Mengel CE, Meriwether WD, Zirkle LG. Inhibition of erythrocyte acetylcholinesterase by peroxides. Biochemistry. 1966 Jan; 5(1):40-4. PMID: 5938954.
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    787. Mengel CE, Zirkle LG, O'Malley BW, Horton BD. Studies of the mechanism of in vivo RBC damage by oxygen. Aerosp Med. 1965 Nov; 36(11):1036-41. PMID: 5860102.
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    788. MENGEL CE, KANN HE, O'MALLEY BW. INCREASED HEMOLYSIS AFTER INTRAMUSCULAR IRON ADMINISTRATION IN PATIENTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA. REPORT OF SIX OCCURRENCES IN FOUR PATIENTS, AND SPECULATIONS ON A POSSIBLE MECHANISM. Blood. 1965 Jul; 26:74-81. PMID: 14314402.
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    789. O'MALLEY BW, ZEFT HJ. DISSEMINATED BONE TUBERCULOSIS WITHOUT PULMONARY MANIFESTATIONS. Am J Med. 1965 Jun; 38:932-6. PMID: 14310009.
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    790. MENGEL CE, HYMAN BN, O'MALLEY BW, HOWELL DA. [1ST LATINAMERICAN SEMINAR ON OCCUPATIONAL HEALTH]. Bol Oficina Sanit Panam. 1964 Oct; 57:329-36. PMID: 14220790.
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    791. MENGEL CE, HYMAN BN, O'MALLEY BW, HOWELL DA. COEXISTENT PAROXYSMAL NOCTURNAL AND COLD HEMOGLOBINURIA PRECEDED BY APLASTIC ANEMIA: A CASE REPORT AND FAMILY STUDY. Blood. 1964 Oct; 24:451-7. PMID: 14220787.
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    792. MENGEL CE, HYMAN BN, O'MALLEY BW, HOWELL DA. [RHEUMATIC FEVER IN THE AMERICAS]. Bol Oficina Sanit Panam. 1964 Oct; 57:321-8. PMID: 14220789.
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    793. MENGEL CE, HYMAN BN, O'MALLEY BW, HOWELL DA. [RHEUMATIC FEVER AND RHEUMATIC HEART DISEASE IN THE AMERICAS]. Bol Oficina Sanit Panam. 1964 Oct; 57:309-20. PMID: 14220788.
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    794. O'MALLEY BW, FIELD JB. EFFECTS OF IONS AND METABOLIC INHIBITORS ON THYROID-STIMULATING-HORMONE STIMULATION OF GLUCOSE OXIDATION IN THYROID SLICES. Biochim Biophys Acta. 1964 Aug 19; 90:349-56. PMID: 14220719.
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