BERT O'MALLEY

TitleDistinguished Service Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Endocrinology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience
    DivisionNeuroscience

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Obstetrics & Gynecology
    DivisionObstetrics and Gynecology


    Collapse Research 
    Collapse research activities and funding
    R01HD008188     (O'MALLEY, BERT W)Sep 1, 1974 - Mar 31, 2024
    NIH
    Reproductive Hormones - Biological and Molecular Actions
    Role: Principal Investigator

    R01HD007857     (O'MALLEY, BERT W)May 1, 1977 - Feb 28, 2022
    NIH
    Sex Hormone Receptor Components and the Cell Genome
    Role: Principal Investigator

    P30HD007495     (O'MALLEY, BERT W)Jun 1, 1978 - Mar 31, 1998
    NIH
    CENTER FOR REPRODUCTIVE BIOLOGY RESEARCH
    Role: Principal Investigator

    T32HD007165     (O'MALLEY, BERT W)Jul 1, 1979 - Apr 30, 2017
    NIH
    Reproductive Biology: Regulatory Mechanisms
    Role: Principal Investigator

    R01DK048896     (O'MALLEY, BERT W)Sep 30, 1994 - Aug 31, 1999
    NIH
    GF/STEROID RECEPTOR INTERACTION IN BREAST CANCER IN VIVO
    Role: Principal Investigator

    U54HD007495     (DEMAYO, FRANCESCO JOHN)Apr 1, 1997 - Mar 31, 2015
    NIH
    Center for Reproductive Biological Research
    Role: Co-Principal Investigator

    P01DK059820     (O'MALLEY, BERT W)Jul 1, 2001 - Jun 30, 2018
    NIH
    Genetic and Metabolic Fingerprints of Coativators Program Project
    Role: Principal Investigator

    U19DK062434     (O'MALLEY, BERT W)Aug 15, 2002 - Jun 30, 2012
    NIH
    Nuclear Receptors and Coregulators in Health and Disease
    Role: Principal Investigator

    U24DK097748     (O'MALLEY, BERT W)Sep 17, 2012 - Aug 31, 2019
    NIH
    A Hub for the Nuclear Receptor Signaling Atlas1
    Role: Principal Investigator

    R01ES023206     (WALKER, CHERYL L)Sep 1, 2013 - May 31, 2018
    NIH
    Epigenetic Programmers Targeted During Developmental Reprogramming
    Role: Co-Principal Investigator

    U01HD082786     (O'MALLEY, BERT W)Apr 14, 2014 - Mar 31, 2019
    NIH/NICHD
    The ERbeta/SRC-1 isoform complex drives endometriosis progression
    Role: Principal Investigator

    R01HD082786     (O'MALLEY, BERT W)Apr 14, 2014 - Mar 31, 2020
    NIH
    The ERbeta/SRC-1 isoform complex drives endometriosis progression
    Role: Principal Investigator

    P01DK113954     (O'MALLEY, BERT W)Jul 1, 2018 - Jun 30, 2023
    NIH
    Nuclear receptors and their Coactivators as Mediators of Systems Metabolism
    Role: Principal Investigator

    R41CA217561     (LONARD, DAVID M)Sep 1, 2018 - Aug 31, 2019
    NIH/NCI
    Small molecule Inhibitors of steroid receptor coactivator to treat breast cancer
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Della Flora Nunes G, Wilson ER, Hurley E, He B, O'Malley BW, Poitelon Y, Wrabetz L, Feltri ML. Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination. Elife. 2021 Sep 14; 10. PMID: 34519641.
      Citations:    Fields:    
    2. Tong CCL, Koptyra M, Raman P, Rathi KS, Choudhari N, Lin X, Seckar T, Wei Z, Kohanski MA, O'Malley BW, Cohen NA, Kennedy DW, Adappa ND, Robertson ES, Baranov E, Kuan EC, Papagiannopoulos P, Jalaly JB, Feldman MD, Storm PB, Resnick AC, Palmer JN. Targeted gene expression profiling of inverted papilloma and squamous cell carcinoma. Int Forum Allergy Rhinol. 2021 Sep 12. PMID: 34510780.
      Citations:    Fields:    
    3. Qin L, Chen J, Lu D, Jain P, Yu Y, Cardenas D, Peng X, Yu X, Xu J, Wang J, O'Malley BW, Lonard DM. Development of improved SRC-3 inhibitors as breast cancer therapeutic agents. Endocr Relat Cancer. 2021 Aug 13; 28(10):657-670. PMID: 34310341.
      Citations:    Fields:    
    4. Sun L, Shimunov D, Tan EX, Swisher-Mcclure S, Lin A, Lukens JN, Basu D, Chalian AA, Cannady SB, Newman JG, Rajasekaran K, O'Malley BW, Rassekh CH, Weinstein GS, Loevner LA, Aggarwal C, Singh A, Cohen RB, Bauml JM, Brody RM. Survival and toxicity in patients with human papilloma virus-associated oropharyngeal squamous cell cancer receiving trimodality therapy including transoral robotic surgery. Head Neck. 2021 Oct; 43(10):3053-3061. PMID: 34170052.
      Citations:    Fields:    
    5. Parhar HS, Weinstein GS, O'Malley BW, Shimunov D, Rassekh CH, Chalian AA, Newman JG, Basu D, Cannady SB, Rajasekaran K, Lin A, Lukens JN, Swisher-McClure S, Cohen RB, Bauml JM, Aggrawal C, Brody RM. Oncologic outcomes of transoral robotic surgery for HPV-negative oropharyngeal carcinomas. Head Neck. 2021 Oct; 43(10):2923-2934. PMID: 34101290.
      Citations:    Fields:    
    6. Carey RM, Brody RM, Shimunov D, Shinn JR, Mady LJ, Rajasekaran K, Cannady SB, Lin A, Lukens JN, Bauml JM, Cohen RB, Basu D, O'Malley BW, Weinstein GS, Newman JG. Locoregional Recurrence in p16-Positive Oropharyngeal Squamous Cell Carcinoma After TORS. Laryngoscope. 2021 Jun 02. PMID: 34076275.
      Citations:    Fields:    
    7. Della-Flora Nunes G, Wilson ER, Marziali LN, Hurley E, Silvestri N, He B, O'Malley BW, Beirowski B, Poitelon Y, Wrabetz L, Feltri ML. Prohibitin 1 is essential to preserve mitochondria and myelin integrity in Schwann cells. Nat Commun. 2021 06 02; 12(1):3285. PMID: 34078899.
      Citations:    Fields:    Translation:AnimalsCells
    8. Yi P, Yu X, Wang Z, O'Malley BW. Steroid receptor-coregulator transcriptional complexes: new insights from CryoEM. Essays Biochem. 2021 Jun 01. PMID: 34061186.
      Citations:    Fields:    
    9. Ding Y, Liu Y, Lee DK, Tong Z, Yu X, Li Y, Xu Y, Lanz RB, O'Malley BW, Xu J. Cell lineage tracing links ERa loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype. Proc Natl Acad Sci U S A. 2021 May 25; 118(21). PMID: 34006643.
      Citations:    Fields:    
    10. Yu W, Singh R, Wang Z, O'Malley BW, Yi P. The E3 ligase TRAF4 promotes IGF signaling by mediating atypical ubiquitination of IRS-1. J Biol Chem. 2021 Jan-Jun; 296:100739. PMID: 33991522.
      Citations:    Fields:    Translation:HumansCells
    11. Yver CM, Shimunov D, Weinstein GS, Rajasekaran K, Cannady SB, Lukens JN, Lin A, Swisher-McClure S, Cohen RB, Aggarwal C, Bauml JM, Loevner LA, Newman JG, Chalian AA, Rassekh CH, Basu D, O'Malley BW, Brody RM. Oncologic and survival outcomes for resectable locally-advanced HPV-related oropharyngeal cancer treated with transoral robotic surgery. Oral Oncol. 2021 Jul; 118:105307. PMID: 33932874.
      Citations:    Fields:    
    12. Rajasekaran K, Carey RM, Lin X, Seckar TD, Wei Z, Chorath K, Newman JG, O'Malley BW, Weinstein GS, Feldman MD, Robertson E. The microbiome of HPV-positive tonsil squamous cell carcinoma and neck metastasis. Oral Oncol. 2021 Jun; 117:105305. PMID: 33905914.
      Citations:    Fields:    
    13. Panigrahi A, O'Malley BW. Mechanisms of enhancer action: the known and the unknown. Genome Biol. 2021 04 15; 22(1):108. PMID: 33858480.
      Citations: 4     Fields:    
    14. Gilad Y, Eliaz Y, Yu Y, Dean AM, Han SJ, Qin L, O'Malley BW, Lonard DM. A genome-scale CRISPR Cas9 dropout screen identifies synthetically lethal targets in SRC-3 inhibited cancer cells. Commun Biol. 2021 03 25; 4(1):399. PMID: 33767353.
      Citations:    Translation:HumansCells
    15. Bankoti K, Generotti C, Hwa T, Wang L, O'Malley BW, Li D. Advances and challenges in adeno-associated viral inner-ear gene therapy for sensorineural hearing loss. Mol Ther Methods Clin Dev. 2021 Jun 11; 21:209-236. PMID: 33850952.
      Citations:    
    16. Mullany LK, Lonard DM, O'Malley BW. Wound Healing-related Functions of the p160 Steroid Receptor Coactivator Family. Endocrinology. 2021 03 01; 162(3). PMID: 33340403.
      Citations:    Fields:    Translation:HumansAnimalsCells
    17. Liu J, Xie Y, Guo J, Li X, Wang J, Jiang H, Peng Z, Wang J, Wang S, Li Q, Ye L, Zhong Y, Zhang Q, Liu X, Lonard DM, Wang J, O'Malley BW, Liu Z. Targeting NSD2-mediated SRC-3 liquid-liquid phase separation sensitizes bortezomib treatment in multiple myeloma. Nat Commun. 2021 02 15; 12(1):1022. PMID: 33589584.
      Citations: 2     Fields:    Translation:HumansCells
    18. Nikolai BC, Jain P, Cardenas DL, York B, Feng Q, McKenna NJ, Dasgupta S, Lonard DM, O'Malley BW. Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs. Sci Rep. 2021 Feb 09; 11(1):3441. PMID: 33564037.
      Citations: 1     Fields:    
    19. Gilad Y, Gellerman G, Lonard DM, O'Malley BW. Drug Combination in Cancer Treatment-From Cocktails to Conjugated Combinations. Cancers (Basel). 2021 Feb 07; 13(4). PMID: 33562300.
      Citations: 1     
    20. Rohira AD, Lonard DM, O'Malley BW. Emerging roles of steroid receptor coactivators in stromal cell responses. J Endocrinol. 2021 02; 248(2):R41-R50. PMID: 33337343.
      Citations:    Fields:    Translation:HumansAnimalsCells
    21. Carey RM, Shimunov D, Weinstein GS, Cannady SB, Lukens JN, Lin A, Swisher-McClure S, Bauml JM, Aggarwal C, Cohen RB, Newman JG, Chalian AA, Rassekh CH, Basu D, O'Malley BW, Rajasekaran K, Brody RM. Increased rate of recurrence and high rate of salvage in patients with human papillomavirus-associated oropharyngeal squamous cell carcinoma with adverse features treated with primary surgery without recommended adjuvant therapy. Head Neck. 2021 04; 43(4):1128-1141. PMID: 33325579.
      Citations: 1     Fields:    Translation:HumansCells
    22. Meng H, Gonzales NM, Lonard DM, Putluri N, Zhu B, Dacso CC, York B, O'Malley BW. XBP1 links the 12-hour clock to NAFLD and regulation of membrane fluidity and lipid homeostasis. Nat Commun. 2020 12 04; 11(1):6215. PMID: 33277471.
      Citations: 2     Fields:    Translation:HumansAnimals
    23. Sataloff RT, Chandra R, Fisher EW, Goldenberg D, Hanna EY, Johnson J, Kennedy DW, Kraus DH, Krouse JH, Link M, Lustig LR, O'Malley BW, Piccirillo JF, Ruben R, Selesnick SH, Sindwani R, Smith RJ, Stewart MG, Tysome J, Weber PC, Welling DB. Consortium of Otolaryngology Journal Editors: Collegiality and Contributions. Otolaryngol Head Neck Surg. 2020 12; 163(6):1067-1069. PMID: 33259266.
      Citations:    Fields:    Translation:Humans
    24. Mullany LK, Rohira AD, Leach JP, Kim JH, Monroe TO, Ortiz AR, Stork B, Gaber MW, Sarkar P, Sikora AG, Rosengart TK, York B, Song Y, Dacso CC, Lonard DM, Martin JF, O'Malley BW. A steroid receptor coactivator stimulator (MCB-613) attenuates adverse remodeling after myocardial infarction. Proc Natl Acad Sci U S A. 2020 12 08; 117(49):31353-31364. PMID: 33229578.
      Citations: 2     Fields:    Translation:AnimalsCells
    25. Parhar HS, Shimunov D, Brody RM, Cannady SB, Newman JG, O'Malley BW, Chalian AA, Rassekh CH, Weinstein GS, Rajasekaran K. Revisiting the Recommendation for Contralateral Tonsillectomy in HPV-Associated Tonsillar Carcinoma. Otolaryngol Head Neck Surg. 2021 06; 164(6):1222-1229. PMID: 33138700.
      Citations:    Fields:    Translation:Humans
    26. Sawant Dessai A, Dominguez MP, Chen UI, Hasper J, Prechtl C, Yu C, Katsuta E, Dai T, Zhu B, Jung SY, Putluri N, Takabe K, Zhang XH, O'Malley BW, Dasgupta S. Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone. Cancer Res. 2021 01 01; 81(1):50-63. PMID: 33115805.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    27. Parasher AK, Lerner DK, Glicksman JT, Miranda SP, Dimentberg R, Ebesutani D, Kohanski M, Lee JYK, Storm PB, O'Malley BW, Palmer JN, Grady MS, Adappa ND. Drivers of In-Hospital Costs Following Endoscopic Transphenoidal Pituitary Surgery. Laryngoscope. 2021 04; 131(4):760-764. PMID: 32830866.
      Citations: 1     Fields:    Translation:Humans
    28. Reny DC, Ranasinghe VJ, Magana LC, Kaufman AC, Chalian AA, O'Malley BW, Weinstein GS, Brody RM. Predictors of Nodal Metastasis in Mucoepidermoid Carcinoma of the Oral Cavity and Oropharynx. ORL J Otorhinolaryngol Relat Spec. 2020; 82(6):327-334. PMID: 32810854.
      Citations:    Fields:    Translation:Humans
    29. Yu X, Yi P, Hamilton RA, Shen H, Chen M, Foulds CE, Mancini MA, Ludtke SJ, Wang Z, O'Malley BW. Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes. Mol Cell. 2020 09 03; 79(5):812-823.e4. PMID: 32668201.
      Citations: 9     Fields:    Translation:HumansCells
    30. Parhar HS, Brody RM, Shimunov D, Rajasekaran K, Rassekh CH, Basu D, O'Malley BW, Chalian AA, Newman JG, Loevner L, Lazor JW, Weinstein GS, Cannady SB. Retropharyngeal Internal Carotid Artery Management in TORS Using Microvascular Reconstruction. Laryngoscope. 2021 03; 131(3):E821-E827. PMID: 32621638.
      Citations:    Fields:    Translation:Humans
    31. O'Malley BW. 90 YEARS OF PROGESTERONE: Reminiscing on the origins of the field of progesterone and estrogen receptor action. J Mol Endocrinol. 2020 07; 65(1):C1-C4. PMID: 32599564.
      Citations: 2     Fields:    Translation:HumansAnimals
    32. Ali S, Balachandran K, O'Malley B. 90 Years of progesterone: Ninety years of progesterone: the 'other' ovarian hormone. J Mol Endocrinol. 2020 07; 65(1):E1-E4. PMID: 32580155.
      Citations:    Fields:    Translation:Humans
    33. Weinstein GS, Cohen R, Lin A, O'Malley BW, Lukens J, Swisher-McClure S, Shanti RM, Newman JG, Parhar HS, Tasche K, Brody RM, Chalian A, Cannady S, Palmer JN, Adappa ND, Kohanski MA, Bauml J, Aggarwal C, Montone K, Livolsi V, Baloch ZW, Jalaly JB, Cooper K, Rajasekaran K, Loevner L, Rassekh C. Penn Medicine Head and Neck Cancer Service Line COVID-19 management guidelines. Head Neck. 2020 Jul; 42(7):1507-1515. PMID: 32584447.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    34. Sataloff RT, Chandra R, Fisher EW, Goldenberg D, Hanna EY, Johnson J, Kennedy DW, Kraus DH, Krouse JH, Link M, Lustig LR, O'Malley BW, Piccirillo JF, Ruben R, Schwartz S, Selesnick SH, Sindwani R, Smith RJ, Stewart MG, Tysome J, Weber PC, Welling DB. Consortium of Otolaryngology Journal Editors: Collegiality and Contributions. Laryngoscope. 2020 06; 130(6):1357-1358. PMID: 32469103.
      Citations:    Fields:    Translation:Humans
    35. Shanti RM, Stoopler ET, Weinstein GS, Newman JG, Cannady SB, Rajasekaran K, Tanaka TI, O'Malley BW, Le AD, Sollecito TP. Considerations in the evaluation and management of oral potentially malignant disorders during the COVID-19 pandemic. Head Neck. 2020 Jul; 42(7):1497-1502. PMID: 32415891.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    36. O'Malley BW. SRC-2 Coactivator: a role in human metabolic evolution and disease. Mol Med. 2020 05 14; 26(1):45. PMID: 32410572.
      Citations: 1     Fields:    Translation:Humans
    37. Parhar HS, Tasche K, Brody RM, Weinstein GS, O'Malley BW, Shanti RM, Newman JG. Topical preparations to reduce SARS-CoV-2 aerosolization in head and neck mucosal surgery. Head Neck. 2020 06; 42(6):1268-1272. PMID: 32333619.
      Citations: 23     Fields:    Translation:HumansCellsPHPublic Health
    38. Rassekh CH, Jenks CM, Ochroch EA, Douglas JE, O'Malley BW, Weinstein GS. Management of the difficult airway in the COVID-19 pandemic: Illustrative complex head and neck cancer scenario. Head Neck. 2020 06; 42(6):1273-1277. PMID: 32298017.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
    39. Lee WK, Kim WG, Fozzatti L, Park S, Zhao L, Willingham MC, Lonard D, O'Malley BW, Cheng SY. Steroid receptor coactivator-3 as a target for anaplastic thyroid cancer. Endocr Relat Cancer. 2020 04; 27(4):209-220. PMID: 31977311.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    40. Gilad Y, Eliaz Y, Yu Y, Han SJ, O'Malley BW, Lonard DM. Author Correction: Drug-induced PD-L1 expression and cell stress response in breast cancer cells can be balanced by drug combination. Sci Rep. 2020 Mar 05; 10(1):4463. PMID: 32132607.
      Citations: 2     Fields:    
    41. Sherins RJ, Santen RJ, Sitruk-Ware R, O'Malley B, Bouchard P. In Memoriam: C. Wayne Bardin, MD (1934 - 2019). Andrology. 2020 Mar; 8(2):264-265. PMID: 32124563.
      Citations:    Fields:    
    42. Shah RR, Maina IW, Patel NN, Triantafillou V, Workman AD, Kuan EC, Tong CCL, Kohanski MA, O'Malley BW, Adappa ND, Palmer JN. Incidence, risk factors, and outcomes of endoscopic sinus surgery after endoscopic skull-base surgery. Int Forum Allergy Rhinol. 2020 04; 10(4):521-525. PMID: 32104979.
      Citations:    Fields:    
    43. Chao TN, Kuan EC, Tong CCL, Kohanski MA, Grady MS, Palmer JN, Adappa ND, O'Malley BW. Surgical Treatment of Sinonasal Mucosal Melanoma in Patients Treated with Systemic Immunotherapy. J Neurol Surg B Skull Base. 2021 Jul; 82(Suppl 3):e148-e154. PMID: 34306930.
      Citations:    
    44. Carey RM, Rajasekaran K, Seckar T, Lin X, Wei Z, Tong CCL, Ranasinghe VJ, Newman JG, O'Malley BW, Weinstein GS, Feldman MD, Robertson ES. The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis. Oncotarget. 2020 Jan 21; 11(3):282-293. PMID: 32076488.
      Citations: 1     Fields:    
    45. Pan Y, Ballance H, Meng H, Gonzalez N, Kim SM, Abdurehman L, York B, Chen X, Schnytzer Y, Levy O, Dacso CC, McClung CA, O'Malley BW, Liu S, Zhu B. 12-h clock regulation of genetic information flow by XBP1s. PLoS Biol. 2020 01; 18(1):e3000580. PMID: 31935211.
      Citations: 5     Fields:    Translation:AnimalsCells
    46. Shen B, Huang D, Ramsey AJ, Ig-Izevbekhai K, Zhang K, Lajud SA, O'Malley BW, Li D. PD-L1 and MRN synergy in platinum-based chemoresistance of head and neck squamous cell carcinoma. Br J Cancer. 2020 03; 122(5):640-647. PMID: 31853007.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    47. Fu X, Pereira R, De Angelis C, Veeraraghavan J, Nanda S, Qin L, Cataldo ML, Sethunath V, Mehravaran S, Gutierrez C, Chamness GC, Feng Q, O'Malley BW, Selenica P, Weigelt B, Reis-Filho JS, Cohen O, Wagle N, Nardone A, Jeselsohn R, Brown M, Rimawi MF, Osborne CK, Schiff R. FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer. Proc Natl Acad Sci U S A. 2019 Dec 11. PMID: 31826955.
      Citations: 15     Fields:    
    48. Swisher-McClure S, Lukens JN, Aggarwal C, Ahn P, Basu D, Bauml JM, Brody R, Chalian A, Cohen RB, Fotouhi-Ghiam A, Geiger G, Gershowitz J, Livolsi V, Mitra N, Montone K, Newman J, Ojerholm E, O'Malley B, Rajasekaran K, Tan E, Weinstein G, Lin A. A Phase 2 Trial of Alternative Volumes of Oropharyngeal Irradiation for De-intensification (AVOID): Omission of the Resected Primary Tumor Bed After Transoral Robotic Surgery for Human Papilloma Virus-Related Squamous Cell Carcinoma of the Oropharynx. Int J Radiat Oncol Biol Phys. 2020 03 15; 106(4):725-732. PMID: 31785337.
      Citations: 13     Fields:    Translation:HumansCellsCTClinical Trials
    49. Han SJ, Lee JE, Cho YJ, Park MJ, O'Malley BW. Genomic Function of Estrogen Receptor ß in Endometriosis. Endocrinology. 2019 11 01; 160(11):2495-2516. PMID: 31504401.
      Citations: 4     Fields:    Translation:HumansAnimals
    50. Holsinger FC, Magnuson JS, Weinstein GS, Chan JYK, Starmer HM, Tsang RKY, Wong EWY, Rassekh CH, Bedi N, Hong SSY, Orosco R, O'Malley BW, Moore EJ. A Next-Generation Single-Port Robotic Surgical System for Transoral Robotic Surgery: Results From Prospective Nonrandomized Clinical Trials. JAMA Otolaryngol Head Neck Surg. 2019 Nov 01; 145(11):1027-1034. PMID: 31536129.
      Citations: 5     Fields:    
    51. Zhang QZ, Chen C, Chang MB, Shanti RM, Cannady SB, O'Malley BW, Shi S, Le AD. Oral Rehabilitation of Patients Sustaining Orofacial Injuries: The UPenn Initiative. Adv Dent Res. 2019 11; 30(2):50-56. PMID: 31633385.
      Citations: 2     Fields:    Translation:Humans
    52. Gilad Y, Eliaz Y, Yu Y, Han SJ, O'Malley BW, Lonard DM. Drug-induced PD-L1 expression and cell stress response in breast cancer cells can be balanced by drug combination. Sci Rep. 2019 10 22; 9(1):15099. PMID: 31641154.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    53. Gershowitz J, Chao HH, Doucette A, Lukens JN, Swisher-McClure S, Weinstein GS, O'Malley BW, Chalian AA, Rassekh CH, Newman JG, Cohen RB, Bauml JM, Aggarwal C, Lin A. Risk of post-operative, pre-radiotherapy contralateral neck recurrence in patients treated with surgery followed by adjuvant radiotherapy for human papilloma virus-associated tonsil cancer. Br J Radiol. 2019 Dec; 92(1104):20190466. PMID: 31600090.
      Citations:    Fields:    Translation:HumansCells
    54. Fathy R, Kuan E, Lee JYK, Grady MS, Alonso-Basanta M, Palmer JN, Adappa ND, O'Malley BW, Brant J. Factors Associated with and Temporal Trends in the Use of Radiation Therapy for the Treatment of Pituitary Adenoma in the National Cancer Database. J Neurol Surg B Skull Base. 2021 Jun; 82(3):285-294. PMID: 34026404.
      Citations: 1     
    55. Chao HH, Schonewolf CA, Tan EX, Swisher-McClure S, Ghiam AF, Weinstein GS, O'Malley BW, Chalian AA, Rassekh CH, Newman JG, Cohen RB, Bauml JM, Aggarwal C, Lin A, Lukens JN. The impact of treatment package time on locoregional control for HPV+ oropharyngeal squamous cell carcinoma treated with surgery and postoperative (chemo)radiation. Head Neck. 2019 11; 41(11):3858-3868. PMID: 31411356.
      Citations: 1     Fields:    Translation:Humans
    56. Grewal AS, Rajasekaran K, Cannady SB, Chalian AA, Ghiam AF, Lin A, LiVolsi V, Lukens JN, Mitra N, Montone KT, Newman JG, O'Malley BW, Rassekh CH, Weinstein GS, Swisher-McClure S. Pharyngeal-sparing radiation for head and neck carcinoma of unknown primary following TORS assisted work-up. Laryngoscope. 2020 03; 130(3):691-697. PMID: 31411747.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    57. Kuan EC, Trent MS, Luu NN, Kohanski MA, Tong CC, O'Malley BW, Adappa ND, Palmer JN. Preventing Restenosis of Marsupialized Rathke Cleft Cysts Using a Nasoseptal Flap Lining. Laryngoscope. 2019 10; 129(10):2258-2261. PMID: 31038765.
      Citations:    Fields:    Translation:Humans
    58. Yang Y, van der Klaauw AA, Zhu L, Cacciottolo TM, He Y, Stadler LKJ, Wang C, Xu P, Saito K, Hinton A, Yan X, Keogh JM, Henning E, Banton MC, Hendricks AE, Bochukova EG, Mistry V, Lawler KL, Liao L, Xu J, O'Rahilly S, Tong Q, O'Malley BW, Farooqi IS, Xu Y. Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis. Nat Commun. 2019 04 12; 10(1):1718. PMID: 30979869.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    59. Henry LE, Haugen TW, Rassekh CH, Adappa ND, Weinstein GS, O'Malley BW. A novel transpalatal-transoral robotic surgery approach to clival chordomas extending into the nasopharynx. Head Neck. 2019 08; 41(8):E133-E140. PMID: 30969009.
      Citations: 4     Fields:    Translation:Humans
    60. Gomez ED, Thaler ER, O'Malley BW, Rassekh CH, Weinstein GS, Newman JG, Brody RM. Techniques for developing and viewing stereoscopic three-dimensional teaching videos for transoral robotic surgery (TORS). J Robot Surg. 2019 Aug; 13(4):581-584. PMID: 30945096.
      Citations:    Fields:    Translation:Humans
    61. Kuan EC, Rereddy SK, Patel NN, Maina IW, Triantafillou V, Kohanski MA, Tong CCL, Nabavizadeh SA, Lee JYK, Grady MS, O'Malley BW, Palmer JN, Adappa ND. Asymptomatic radiographic sinonasal inflammation does not affect pituitary surgery outcomes. Laryngoscope. 2019 07; 129(7):1545-1548. PMID: 30835847.
      Citations: 1     Fields:    Translation:Humans
    62. Petrov D, Spadola M, Berger C, Glauser G, Mahmoud AF, O'Malley B, Malhotra NR. Novel approach using ultrasonic bone curettage and transoral robotic surgery for en bloc resection of cervical spine chordoma: case report. J Neurosurg Spine. 2019 Mar 01; 1-6. PMID: 30835711.
      Citations:    Fields:    
    63. Kumar R, Murad F, Bogler O, O'Malley BW, Hortobagyi GN. John Mendelsohn: A visionary scientist, oncologist and leader. Genes Cancer. 2019; 10(5-6):109-118. PMID: 31798764.
      Citations: 1     
    64. Sharma S, Zhou O, Thompson R, Gabriel P, Chalian A, Rassekh C, Weinstein GS, O'Malley BW, Aggarwal C, Bauml J, Cohen RB, Lukens JN, Swisher-McClure S, Ghiam AF, Ahn PH, Lin A. Quality of Life of Postoperative Photon versus Proton Radiation Therapy for Oropharynx Cancer. Int J Part Ther. 2018; 5(2):11-17. PMID: 31773030.
      Citations: 6     
    65. McCann AC, Berger C, Mahmoud AF, Kuan EC, Malhotra NR, O'Malley BW. Novel approach using transoral robotic surgery for resection of cervical spine chordoma. Laryngoscope. 2019 06; 129(6):1395-1399. PMID: 30456816.
      Citations:    Fields:    Translation:Humans
    66. Bader DA, Hartig SM, Putluri V, Foley C, Hamilton MP, Smith EA, Saha PK, Panigrahi A, Walker C, Zong L, Martini-Stoica H, Chen R, Rajapakshe K, Coarfa C, Sreekumar A, Mitsiades N, Bankson JA, Ittmann MM, O'Malley BW, Putluri N, McGuire SE. Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer. Nat Metab. 2019 01; 1(1):70-85. PMID: 31198906.
      Citations: 30     Translation:HumansAnimalsCells
    67. Song X, Chen H, Zhang C, Yu Y, Chen Z, Liang H, Van Buren G, McElhany AL, Fisher WE, Lonard DM, O'Malley BW, Wang J. SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma. Cancer Lett. 2019 02 01; 442:310-319. PMID: 30423406.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    68. Szwarc MM, Hai L, Gibbons WE, White LD, Mo Q, Kommagani R, Lanz RB, DeMayo FJ, O'Malley BW, Lydon JP. Retinoid signaling controlled by SRC-2 in decidualization revealed by transcriptomics Reproduction. 2018 10 16; 156(5):387-395. PMID: 30325183.
      Citations: 6     Fields:    Translation:HumansCells
    69. Cheng D, Vemulapalli V, Lu Y, Shen J, Aoyagi S, Fry CJ, Yang Y, Foulds CE, Stossi F, Treviño LS, Mancini MA, O'Malley BW, Walker CL, Boyer TG, Bedford MT. CARM1 methylates MED12 to regulate its RNA-binding ability. Life Sci Alliance. 2018 Oct; 1(5):e201800117. PMID: 30456381.
      Citations: 15     Fields:    
    70. Antoulas AC, Zhu B, Zhang Q, York B, O'Malley BW, Dacso CC. A novel mathematical method for disclosing oscillations in gene transcription: A comparative study. PLoS One. 2018; 13(9):e0198503. PMID: 30231032.
      Citations: 4     Fields:    Translation:AnimalsCells
    71. Szwarc MM, Kommagani R, Putluri V, Dubrulle J, Stossi F, Mancini MA, Coarfa C, Lanz RB, Putluri N, DeMayo FJ, Lydon JP, O'Malley BW. Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells. Sci Rep. 2018 09 03; 8(1):13134. PMID: 30177747.
      Citations: 1     Fields:    Translation:HumansCells
    72. Workman AD, Brody RM, Kuan EC, Baranov E, Brooks SG, Alonso-Basanta M, Newman JG, Rassekh CH, Chalian AA, Chiu AG, Weinstein GS, Feldman MD, Adappa ND, O'Malley BW, Palmer JN. Sinonasal Undifferentiated Carcinoma: A 15-Year Single Institution Experience. J Neurol Surg B Skull Base. 2019 Feb; 80(1):88-95. PMID: 30733906.
      Citations:    
    73. Singh R, Karri D, Shen H, Shao J, Dasgupta S, Huang S, Edwards DP, Ittmann MM, O'Malley BW, Yi P. TRAF4-mediated ubiquitination of NGF receptor TrkA regulates prostate cancer metastasis. J Clin Invest. 2018 07 02; 128(7):3129-3143. PMID: 29715200.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    74. Zhu B, Dacso CC, O'Malley BW. Unveiling "Musica Universalis" of the Cell: A Brief History of Biological 12-Hour Rhythms. J Endocr Soc. 2018 Jul 01; 2(7):727-752. PMID: 29978151.
      Citations: 5     
    75. Tanaka K, Martinez GJ, Yan X, Long W, Ichiyama K, Chi X, Kim BS, Reynolds JM, Chung Y, Tanaka S, Liao L, Nakanishi Y, Yoshimura A, Zheng P, Wang X, Tian Q, Xu J, O'Malley BW, Dong C. Regulation of Pathogenic T Helper 17 Cell Differentiation by Steroid Receptor Coactivator-3. Cell Rep. 2018 05 22; 23(8):2318-2329. PMID: 29791844.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    76. Panigrahi AK, Foulds CE, Lanz RB, Hamilton RA, Yi P, Lonard DM, Tsai MJ, Tsai SY, O'Malley BW. SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription. Mol Cell. 2018 05 17; 70(4):679-694.e7. PMID: 29775582.
      Citations: 13     Fields:    Translation:HumansCells
    77. Gates LA, Gu G, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, Jung SY, Malovannaya A, Li S, Shao J, Roeder RG, Ellis MJ, Qin J, Fuqua SAW, O'Malley BW, Foulds CE. Proteomic profiling identifies key coactivators utilized by mutant ERa proteins as potential new therapeutic targets. Oncogene. 2018 08; 37(33):4581-4598. PMID: 29748621.
      Citations: 21     Fields:    Translation:HumansCells
    78. Kayyali MN, Wooltorton JRA, Ramsey AJ, Lin M, Chao TN, Tsourkas A, O'Malley BW, Li D. A novel nanoparticle delivery system for targeted therapy of noise-induced hearing loss. J Control Release. 2018 06 10; 279:243-250. PMID: 29673641.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    79. Cho YJ, Lee JE, Park MJ, O'Malley BW, Han SJ. Bufalin suppresses endometriosis progression by inducing pyroptosis and apoptosis. J Endocrinol. 2018 06; 237(3):255-269. PMID: 29636364.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    80. Dasgupta S, Rajapakshe K, Zhu B, Nikolai BC, Yi P, Putluri N, Choi JM, Jung SY, Coarfa C, Westbrook TF, Zhang XH, Foulds CE, Tsai SY, Tsai MJ, O'Malley BW. Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. Nature. 2018 04; 556(7700):249-254. PMID: 29615789.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    81. Padmanabhan A, Candelaria N, Wong KK, Nikolai BC, Lonard DM, O'Malley BW, Richards JS. USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells. Nat Commun. 2018 03 28; 9(1):1270. PMID: 29593334.
      Citations: 23     Fields:    Translation:HumansCells
    82. Chandra R, Fisher EW, Jones TM, Kennedy DW, Kraus DH, Krouse JH, Link M, Lustig LR, O'Malley BW, Piccirillo JF, Ruben R, Sataloff RT, Schwartz S, Sindwani R, Smith RJ, Stewart MG, Weber PC, Welling DB, Youngs R. Open access: Is there a predator at the door? Laryngoscope. 2018 06; 128(6):1255-1256. PMID: 29572916.
      Citations:    Fields:    
    83. Chandra R, Fisher EW, Jones TM, Kennedy DW, Kraus DH, Krouse JH, Link M, Lustig LR, O'Malley BW, Piccirillo JF, Ruben R, Sataloff RT, Schwartz S, Sindwani R, Smith RJ, Stewart MG, Weber PC, Welling DB, Youngs R. Open Access: Is There a Predator at the Door? Otol Neurotol. 2018 03; 39(3):271-272. PMID: 29424818.
      Citations:    Fields:    
    84. Chandra R, Fisher EW, Jones TM, Kennedy DW, Kraus DH, Krouse JH, Link M, Lustig LR, O'Malley BW, Piccirillo JF, Ruben R, Sataloff RT, Sindwani R, Smith RJ, Stewart MG, Weber PC, Welling DB, Youngs R. Open Access: Is There a Predator at the Door? Otolaryngol Head Neck Surg. 2018 03; 158(3):401-402. PMID: 29470137.
      Citations: 2     Fields:    Translation:Humans
    85. Kayyali MN, Ramsey AJ, Higbee-Dempsey EM, Yan L, O'Malley BW, Tsourkas A, Li D. The Development of a Nano-based Approach to Alleviate Cisplatin-Induced Ototoxicity. J Assoc Res Otolaryngol. 2018 04; 19(2):123-132. PMID: 29349595.
      Citations: 1     Fields:    Translation:Animals
    86. Gates LA, Foulds CE, O'Malley BW. Histone Marks in the 'Driver's Seat': Functional Roles in Steering the Transcription Cycle. Trends Biochem Sci. 2017 12; 42(12):977-989. PMID: 29122461.
      Citations: 33     Fields:    Translation:HumansCells
    87. Ahn PH, Finlay JC, Gallagher-Colombo SM, Quon H, O'Malley BW, Weinstein GS, Chalian A, Malloy K, Sollecito T, Greenberg M, Simone CB, McNulty S, Lin A, Zhu TC, Livolsi V, Feldman M, Mick R, Cengel KA, Busch TM. Lesion oxygenation associates with clinical outcomes in premalignant and early stage head and neck tumors treated on a phase 1 trial of photodynamic therapy. Photodiagnosis Photodyn Ther. 2018 Mar; 21:28-35. PMID: 29113960.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    88. Kayyali MN, Wright AC, Ramsey AJ, Brant JA, Stein JM, O'Malley BW, Li D. Challenges and opportunities in developing targeted molecular imaging to determine inner ear defects of sensorineural hearing loss. Nanomedicine. 2018 02; 14(2):397-404. PMID: 29074310.
      Citations: 2     Fields:    Translation:HumansAnimals
    89. Shanti RM, O'Malley BW. Surgical Management of Oral Cancer. Dent Clin North Am. 2018 01; 62(1):77-86. PMID: 29126495.
      Citations: 4     Fields:    Translation:Humans
    90. Zhang Z, Nikolai BC, Gates LA, Jung SY, Siwak EB, He B, Rice AP, O'Malley BW, Feng Q. Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency. Nucleic Acids Res. 2017 Sep 19; 45(16):9348-9360. PMID: 28637181.
      Citations: 16     Fields:    Translation:HumansCells
    91. Camden AJ, Szwarc MM, Chadchan SB, DeMayo FJ, O'Malley BW, Lydon JP, Kommagani R. Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization. Mol Hum Reprod. 2017 09 01; 23(9):646-653. PMID: 28911214.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    92. Kayyali MN, Brake L, Ramsey AJ, Wright AC, O'Malley BW, Li DD. A Novel Nano-approach for Targeted Inner Ear Imaging. J Nanomed Nanotechnol. 2017 Aug; 8(4). PMID: 29104815.
      Citations: 3     
    93. Yi P, Wang Z, Feng Q, Chou CK, Pintilie GD, Shen H, Foulds CE, Fan G, Serysheva I, Ludtke SJ, Schmid MF, Hung MC, Chiu W, O'Malley BW. Structural and Functional Impacts of ER Coactivator Sequential Recruitment. Mol Cell. 2017 Sep 07; 67(5):733-743.e4. PMID: 28844863.
      Citations: 26     Fields:    Translation:HumansCells
    94. Gates LA, Shi J, Rohira AD, Feng Q, Zhu B, Bedford MT, Sagum CA, Jung SY, Qin J, Tsai MJ, Tsai SY, Li W, Foulds CE, O'Malley BW. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017 09 01; 292(35):14456-14472. PMID: 28717009.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    95. Bur AM, Gomez ED, Newman JG, Weinstein GS, O'Malley BW, Rassekh CH, Kuchenbecker KJ. Evaluation of high-fidelity simulation as a training tool in transoral robotic surgery. Laryngoscope. 2017 12; 127(12):2790-2795. PMID: 28657696.
      Citations: 2     Fields:    Translation:Animals
    96. Routman DM, Funk RK, Tangsriwong K, Lin A, Keeney MG, García JJ, Zarka MA, Lewis JT, Stoddard DG, Moore EJ, Day CN, Zhai Q, Price KA, Lukens JN, Swisher-McClure S, Weinstein GS, O'Malley BW, Foote RL, Ma DJ. Relapse Rates With Surgery Alone in Human Papillomavirus-Related Intermediate- and High-Risk Group Oropharynx Squamous Cell Cancer: A Multi-Institutional Review. Int J Radiat Oncol Biol Phys. 2017 11 15; 99(4):938-946. PMID: 28847412.
      Citations:    Fields:    Translation:HumansCells
    97. Banerjee S, Tian T, Wei Z, Peck KN, Shih N, Chalian AA, O'Malley BW, Weinstein GS, Feldman MD, Alwine J, Robertson ES. Microbial Signatures Associated with Oropharyngeal and Oral Squamous Cell Carcinomas. Sci Rep. 2017 06 22; 7(1):4036. PMID: 28642609.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    98. Rohira AD, Yan F, Wang L, Wang J, Zhou S, Lu A, Yu Y, Xu J, Lonard DM, O'Malley BW. Targeting SRC Coactivators Blocks the Tumor-Initiating Capacity of Cancer Stem-like Cells. Cancer Res. 2017 08 15; 77(16):4293-4304. PMID: 28611048.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    99. Zhu B, Zhang Q, Pan Y, Mace EM, York B, Antoulas AC, Dacso CC, O'Malley BW. A Cell-Autonomous Mammalian 12 hr Clock Coordinates Metabolic and Stress Rhythms. Cell Metab. 2017 Jun 06; 25(6):1305-1319.e9. PMID: 28591634.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    100. Geng C, Kaochar S, Li M, Rajapakshe K, Fiskus W, Dong J, Foley C, Dong B, Zhang L, Kwon OJ, Shah SS, Bolaki M, Xin L, Ittmann M, O'Malley BW, Coarfa C, Mitsiades N. SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein. Oncogene. 2017 08 17; 36(33):4767-4777. PMID: 28414305.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    101. Hatten KM, O'Malley BW, Bur AM, Patel MR, Rassekh CH, Newman JG, Cannady SB, Chalian AA, Hodnett BL, Lin A, Lukens JN, Cohen RB, Bauml JM, Montone KT, Livolsi VA, Weinstein GS. Transoral Robotic Surgery-Assisted Endoscopy With Primary Site Detection and Treatment in Occult Mucosal Primaries. JAMA Otolaryngol Head Neck Surg. 2017 03 01; 143(3):267-273. PMID: 27930761.
      Citations: 6     Fields:    Translation:Humans
    102. Xu Y, O'Malley BW, Elmquist JK. Brain nuclear receptors and body weight regulation. J Clin Invest. 2017 Apr 03; 127(4):1172-1180. PMID: 28218618.
      Citations: 9     Fields:    Translation:HumansAnimals
    103. Xu Q, Shanti RM, Zhang Q, Cannady SB, O'Malley BW, Le AD. A Gingiva-Derived Mesenchymal Stem Cell-Laden Porcine Small Intestinal Submucosa Extracellular Matrix Construct Promotes Myomucosal Regeneration of the Tongue. Tissue Eng Part A. 2017 04; 23(7-8):301-312. PMID: 27923325.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    104. Grover S, Mitra N, Wan F, Lukens JN, Sharma S, Bauman J, Masroor F, Cohen RB, Desai A, Algazy K, Alonso-Basanta M, Ahn P, Kevin Teo BK, Chalian AA, Weinstein GS, O'Malley BW, Lin A. A Single-institution Comparison of Cetuximab, Carboplatin, and Paclitaxel Induction Chemotherapy Followed by Chemoradiation (CRT) Versus CRT for Locally Advanced Squamous Cell Carcinoma of the Head and Neck (LA-SCCHN). Am J Clin Oncol. 2016 10; 39(5):522-7. PMID: 27441910.
      Citations:    Fields:    Translation:Humans
    105. O'Malley BW. Origins of the Field of Molecular Endocrinology: A Personal Perspective. Mol Endocrinol. 2016 10; 30(10):1015-1018. PMID: 27690769.
      Citations: 1     Fields:    Translation:HumansAnimals
    106. Lonard DM, O'Malley BW. Molecular Pathways: Targeting Steroid Receptor Coactivators in Cancer. Clin Cancer Res. 2016 Nov 15; 22(22):5403-5407. PMID: 27654711.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    107. Ahn PH, Mitra N, Alonso-Basanta M, Palmer JN, Adappa ND, O'Malley BW, Rassekh C, Chalian A, Cohen RB, Lin A. Risk of lymph node metastasis and recommendations for elective nodal treatment in squamous cell carcinoma of the nasal cavity and maxillary sinus: a SEER analysis. Acta Oncol. 2016 Sep - Oct; 55(9-10):1107-1114. PMID: 27685421.
      Citations: 6     Fields:    Translation:Humans
    108. Fleet T, Stashi E, Zhu B, Rajapakshe K, Marcelo KL, Kettner NM, Gorman BK, Coarfa C, Fu L, O'Malley BW, York B. Genetic and Environmental Models of Circadian Disruption Link SRC-2 Function to Hepatic Pathology. J Biol Rhythms. 2016 10; 31(5):443-60. PMID: 27432117.
      Citations: 7     Fields:    Translation:HumansAnimals
    109. Brody RM, Pandey NC, Bur AM, O'Malley BW, Rassekh CH, Weinstein GS, Chalian AA, Newman JG, Cannady SB. Anterior lateral thigh osteomyocutaneous free flap reconstruction in the head and neck: The anterolateral thigh osteomyocutaneous femur bone flap. Head Neck. 2016 12; 38(12):1788-1793. PMID: 27310816.
      Citations: 2     Fields:    Translation:Humans
    110. Wang Q, Trevino LS, Wong RL, Medvedovic M, Chen J, Ho SM, Shen J, Foulds CE, Coarfa C, O'Malley BW, Shilatifard A, Walker CL. Reprogramming of the Epigenome by MLL1 Links Early-Life Environmental Exposures to Prostate Cancer Risk. Mol Endocrinol. 2016 Aug; 30(8):856-71. PMID: 27219490.
      Citations: 31     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    111. Khalili S, Worrall DM, Brooks S, Morris SM, Farquhar D, Newman JG, Learned KO, Ahn PH, Craig J, Kennedy DW, O'Malley BW, Palmer JN, Adappa ND. Endoscopy versus imaging: Analysis of surveillance methods in sinonasal malignancy. Head Neck. 2016 08; 38(8):1229-33. PMID: 27142811.
      Citations: 2     Fields:    Translation:Humans
    112. Wang L, Lonard DM, O'Malley BW. The Role of Steroid Receptor Coactivators in Hormone Dependent Cancers and Their Potential as Therapeutic Targets. Horm Cancer. 2016 08; 7(4):229-35. PMID: 27125199.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    113. Song X, Chen J, Zhao M, Zhang C, Yu Y, Lonard DM, Chow DC, Palzkill T, Xu J, O'Malley BW, Wang J. Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3. Proc Natl Acad Sci U S A. 2016 May 03; 113(18):4970-5. PMID: 27084884.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    114. Rassekh CH, O'Malley BW, Bewley AF, Montone KT, Livolsi VA, Weinstein GS. Feasibility and relevance of level I substation node counts in oropharyngeal carcinoma. Head Neck. 2016 08; 38(8):1194-200. PMID: 27028011.
      Citations: 2     Fields:    Translation:Humans
    115. Farquhar D, Kim L, Worrall D, Chiu A, Lee JY, Khalili S, Grady S, O'Malley BW, Kennedy DW, Newman JG, Palmer JN, Adappa ND. Propensity score analysis of endoscopic and open approaches to malignant paranasal and anterior skull base tumor outcomes. Laryngoscope. 2016 08; 126(8):1724-9. PMID: 26972568.
      Citations: 7     Fields:    Translation:Humans
    116. Xu J, Zhou L, Ji L, Chen F, Fortmann K, Zhang K, Liu Q, Li K, Wang W, Wang H, Xie W, Wang Q, Liu J, Zheng B, Zhang P, Huang S, Shi T, Zhang B, Dang Y, Chen J, O'Malley BW, Moses RE, Wang P, Li L, Xiao J, Hoffmann A, Li X. The REG?-proteasome forms a regulatory circuit with I?B? and NF?B in experimental colitis. Nat Commun. 2016 Feb 22; 7:10761. PMID: 26899380.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    117. Ahn PH, Quon H, O'Malley BW, Weinstein G, Chalian A, Malloy K, Atkins JH, Sollecito T, Greenberg M, McNulty S, Lin A, Zhu TC, Finlay JC, Cengel K, Livolsi V, Feldman M, Mick R, Busch TM. Toxicities and early outcomes in a phase 1 trial of photodynamic therapy for premalignant and early stage head and neck tumors. Oral Oncol. 2016 Apr; 55:37-42. PMID: 26865261.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    118. Nikolai BC, Lanz RB, York B, Dasgupta S, Mitsiades N, Creighton CJ, Tsimelzon A, Hilsenbeck SG, Lonard DM, Smith CL, O'Malley BW. HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes. Cancer Res. 2016 Mar 15; 76(6):1463-75. PMID: 26833126.
      Citations: 13     Fields:    Translation:HumansCells
    119. Li L, Chao T, Brant J, O'Malley B, Tsourkas A, Li D. Advances in nano-based inner ear delivery systems for the treatment of sensorineural hearing loss. Adv Drug Deliv Rev. 2017 01 01; 108:2-12. PMID: 26796230.
      Citations: 20     Fields:    Translation:Humans
    120. Foulds CE, Panigrahi AK, Coarfa C, Lanz RB, O'Malley BW. Long Noncoding RNAs as Targets and Regulators of Nuclear Receptors. Curr Top Microbiol Immunol. 2016; 394:143-76. PMID: 26362934.
      Citations: 4     Fields:    Translation:HumansCells
    121. Zhang Z, Brown JC, O'Malley BW, Troxel AB, Bauml JM, Rubnitz KR, Grosso CM, Weinstein GS, Schmitz KH. Post-treatment weight change in oral cavity and oropharyngeal squamous cell carcinoma. Support Care Cancer. 2016 May; 24(5):2333-2340. PMID: 26619995.
      Citations: 1     Fields:    Translation:Humans
    122. Zhu B, Gates LA, Stashi E, Dasgupta S, Gonzales N, Dean A, Dacso CC, York B, O'Malley BW. Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading. Mol Cell. 2015 Dec 03; 60(5):769-783. PMID: 26611104.
      Citations: 33     Fields:    Translation:AnimalsCells
    123. Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Correction: Perturbing the Cellular Levels of Steroid Receptor Coactivator-2 Impairs Murine Endometrial Function. PLoS One. 2015; 10(11):e0143652. PMID: 26580555.
      Citations:    Fields:    
    124. Han SJ, Jung SY, Wu SP, Hawkins SM, Park MJ, Kyo S, Qin J, Lydon JP, Tsai SY, Tsai MJ, DeMayo FJ, O'Malley BW. Estrogen Receptor ß Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 2015 Nov 05; 163(4):960-74. PMID: 26544941.
      Citations: 79     Fields:    Translation:HumansAnimals
    125. Han SJ, Begum K, Foulds CE, Hamilton RA, Bailey S, Malovannaya A, Chan D, Qin J, O'Malley BW. The Dual Estrogen Receptor a Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety. Mol Pharmacol. 2016 Jan; 89(1):14-26. PMID: 26487511.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    126. Fleet T, Zhang B, Lin F, Zhu B, Dasgupta S, Stashi E, Tackett B, Thevananther S, Rajapakshe KI, Gonzales N, Dean A, Mao J, Timchenko N, Malovannaya A, Qin J, Coarfa C, DeMayo F, Dacso CC, Foulds CE, O'Malley BW, York B. SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis. Proc Natl Acad Sci U S A. 2015 Nov 03; 112(44):E6068-77. PMID: 26487680.
      Citations: 5     Fields:    Translation:AnimalsCells
    127. Song X, Zhang C, Zhao M, Chen H, Liu X, Chen J, Lonard DM, Qin L, Xu J, Wang X, Li F, O'Malley BW, Wang J. Steroid Receptor Coactivator-3 (SRC-3/AIB1) as a Novel Therapeutic Target in Triple Negative Breast Cancer and Its Inhibition with a Phospho-Bufalin Prodrug. PLoS One. 2015; 10(10):e0140011. PMID: 26431029.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    128. Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BW. Correction: Acceleration of the Glycolytic Flux by Steroid Receptor Coactivator-2 Is Essential for Endometrial Decidualization. PLoS Genet. 2015 Sep; 11(9):e1005515. PMID: 26418340.
      Citations: 1     Fields:    
    129. Lv Y, Meng B, Dong H, Jing T, Wu N, Yang Y, Huang L, Moses RE, O'Malley BW, Mei B, Li X. Upregulation of GSK3ß Contributes to Brain Disorders in Elderly REG?-knockout Mice. Neuropsychopharmacology. 2016 Apr; 41(5):1340-9. PMID: 26370326.
      Citations: 1     Fields:    Translation:AnimalsCells
    130. Coarfa C, Fiskus W, Eedunuri VK, Rajapakshe K, Foley C, Chew SA, Shah SS, Geng C, Shou J, Mohamed JS, O'Malley BW, Mitsiades N. Comprehensive proteomic profiling identifies the androgen receptor axis and other signaling pathways as targets of microRNAs suppressed in metastatic prostate cancer. Oncogene. 2016 05 05; 35(18):2345-56. PMID: 26364608.
      Citations: 39     Fields:    Translation:HumansCells
    131. Tanaka N, Lajud SA, Ramsey A, Szymanowski AR, Ruffner R, O'Malley BW, Li D. Application of infrared-based molecular imaging to a mouse model with head and neck cancer. Head Neck. 2016 04; 38 Suppl 1:E1351-7. PMID: 26348614.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    132. Jin F, Bhowmik SK, Putluri V, Gu F, Gohlke J, Von Rundstedt FC, Dasgupta S, Krishnapuram R, O'Malley BW, Sreekumar A, Putluri N. A Novel [15N] Glutamine Flux using LC-MS/MS-SRM for Determination of Nucleosides and Nucleobases. J Anal Bioanal Tech. 2015 Oct; 6(5). PMID: 27158554.
      Citations: 1     
    133. Szwarc MM, Lydon JP, O'Malley BW. Reprint of "Steroid receptor coactivators as therapeutic targets in the female reproductive system". J Steroid Biochem Mol Biol. 2015 Sep; 153:144-50. PMID: 26291832.
      Citations:    Fields:    
    134. Wang L, Yu Y, Chow DC, Yan F, Hsu CC, Stossi F, Mancini MA, Palzkill T, Liao L, Zhou S, Xu J, Lonard DM, O'Malley BW. Characterization of a Steroid Receptor Coactivator Small Molecule Stimulator that Overstimulates Cancer Cells and Leads to Cell Stress and Death. Cancer Cell. 2015 Aug 10; 28(2):240-52. PMID: 26267537.
      Citations: 42     Fields:    Translation:HumansCells
    135. Thaler ER, Rassekh CH, Lee JM, Weinstein GS, O'Malley BW. Outcomes for multilevel surgery for sleep apnea: Obstructive sleep apnea, transoral robotic surgery, and uvulopalatopharyngoplasty. Laryngoscope. 2016 Jan; 126(1):266-9. PMID: 26153069.
      Citations: 9     Fields:    Translation:Humans
    136. Szwarc MM, Lydon JP, O'Malley BW. Steroid receptor coactivators as therapeutic targets in the female reproductive system. J Steroid Biochem Mol Biol. 2015 Nov; 154:32-8. PMID: 26151740.
      Citations: 4     Fields:    Translation:HumansAnimals
    137. Gallagher-Colombo SM, Quon H, Malloy KM, Ahn PH, Cengel KA, Simone CB, Chalian AA, O'Malley BW, Weinstein GS, Zhu TC, Putt ME, Finlay JC, Busch TM. Measuring the Physiologic Properties of Oral Lesions Receiving Fractionated Photodynamic Therapy. Photochem Photobiol. 2015 Sep-Oct; 91(5):1210-8. PMID: 26037487.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    138. Gao L, Rabbitt EH, Condon JC, Renthal NE, Johnston JM, Mitsche MA, Chambon P, Xu J, O'Malley BW, Mendelson CR. Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest. 2015 Jul 01; 125(7):2808-24. PMID: 26098214.
      Citations: 35     Fields:    Translation:AnimalsCells
    139. Eedunuri VK, Rajapakshe K, Fiskus W, Geng C, Chew SA, Foley C, Shah SS, Shou J, Mohamed JS, Coarfa C, O'Malley BW, Mitsiades N. miR-137 Targets p160 Steroid Receptor Coactivators SRC1, SRC2, and SRC3 and Inhibits Cell Proliferation. Mol Endocrinol. 2015 Aug; 29(8):1170-83. PMID: 26066330.
      Citations: 18     Fields:    Translation:HumansCells
    140. Kovatch KJ, Purkey MT, Martinez-Lage M, Gausas RE, Loevner LA, Grady MS, O'Malley BW, Rassekh CH. Management of an expansile orbital mass: Plexiform neurofibroma decompression by orbitozygomatic approach. Laryngoscope. 2015 Nov; 125(11):2457-60. PMID: 25960281.
      Citations:    Fields:    Translation:Humans
    141. Kaczmar JM, Tan KS, Heitjan DF, Lin A, Ahn PH, Newman JG, Rassekh CH, Chalian AA, O'Malley BW, Cohen RB, Weinstein GS. HPV-related oropharyngeal cancer: Risk factors for treatment failure in patients managed with primary transoral robotic surgery. Head Neck. 2016 Jan; 38(1):59-65. PMID: 25197014.
      Citations: 9     Fields:    Translation:HumansCells
    142. Kang YK, Putluri N, Maity S, Tsimelzon A, Ilkayeva O, Mo Q, Lonard D, Michailidis G, Sreekumar A, Newgard CB, Wang M, Tsai SY, Tsai MJ, O'Malley BW. CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-a-Gabpa and stress-induced adaptive responses via NF-?B-cMYC. PLoS Genet. 2015 Apr; 11(4):e1005116. PMID: 25830341.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    143. Lonard DM, Xu J, O'Malley BW. Bufalin is a steroid receptor coactivator inhibitor-response. Cancer Res. 2015 Mar 15; 75(6):1157. PMID: 25736684.
      Citations: 2     Fields:    Translation:HumansAnimals
    144. Yi P, Wang Z, Feng Q, Pintilie GD, Foulds CE, Lanz RB, Ludtke SJ, Schmid MF, Chiu W, O'Malley BW. Structure of a biologically active estrogen receptor-coactivator complex on DNA. Mol Cell. 2015 Mar 19; 57(6):1047-1058. PMID: 25728767.
      Citations: 47     Fields:    Translation:HumansCells
    145. Dasgupta S, Putluri N, Long W, Zhang B, Wang J, Kaushik AK, Arnold JM, Bhowmik SK, Stashi E, Brennan CA, Rajapakshe K, Coarfa C, Mitsiades N, Ittmann MM, Chinnaiyan AM, Sreekumar A, O'Malley BW. Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis. J Clin Invest. 2015 Mar 02; 125(3):1174-88. PMID: 25664849.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    146. Lajud SA, Nagda DA, Qiao P, Tanaka N, Civantos A, Gu R, Cheng Z, Tsourkas A, O'Malley BW, Li D. A novel chitosan-hydrogel-based nanoparticle delivery system for local inner ear application. Otol Neurotol. 2015 Feb; 36(2):341-7. PMID: 25587675.
      Citations: 14     Fields:    Translation:Animals
    147. Sperry SM, O'Malley BW, Weinstein GS. The University of Pennsylvania curriculum for training otorhinolaryngology residents in transoral robotic surgery. ORL J Otorhinolaryngol Relat Spec. 2014; 76(6):342-52. PMID: 25591714.
      Citations: 2     Fields:    Translation:Humans
    148. Omolehinwa TT, Musbah T, Desai B, O'Malley BW, Stoopler ET. Neuralgia associated with transcutaneous electrical nerve stimulation therapy in a patient initially diagnosed with temporomandibular disorder. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015 Mar; 119(3):e101-4. PMID: 25660829.
      Citations: 1     Fields:    Translation:Humans
    149. McKenna NJ, Evans RM, O'Malley BW. Nuclear Receptor Signaling: a home for nuclear receptor and coregulator signaling research. Nucl Recept Signal. 2014; 12:e006. PMID: 25614732.
      Citations: 7     Fields:    Translation:Cells
    150. He B, Lanz RB, Fiskus W, Geng C, Yi P, Hartig SM, Rajapakshe K, Shou J, Wei L, Shah SS, Foley C, Chew SA, Eedunuri VK, Bedoya DJ, Feng Q, Minami T, Mitsiades CS, Frolov A, Weigel NL, Hilsenbeck SG, Rosen DG, Palzkill T, Ittmann MM, Song Y, Coarfa C, O'Malley BW, Mitsiades N. GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex. Proc Natl Acad Sci U S A. 2014 Dec 23; 111(51):18261-6. PMID: 25489091.
      Citations: 47     Fields:    Translation:HumansCells
    151. Weinstein GS, O'Malley BW, Rinaldo A, Silver CE, Werner JA, Ferlito A. Understanding contraindications for transoral robotic surgery (TORS) for oropharyngeal cancer. Eur Arch Otorhinolaryngol. 2015 Jul; 272(7):1551-2. PMID: 25327689.
      Citations: 16     Fields:    
    152. Lajud SA, Nagda DA, Yamashita T, Zheng J, Tanaka N, Abuzeid WM, Civantos A, Bezpalko O, O'Malley BW, Li D. Dual disruption of DNA repair and telomere maintenance for the treatment of head and neck cancer. Clin Cancer Res. 2014 Dec 15; 20(24):6465-78. PMID: 25324139.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    153. Gustafsson JA, Katzenellenbogen B, Jameson JL, Roth J, Melmed S, McDonnell D, Wartofsky L, Crowley WF, Griz LH, Becker C, Moore DD, Drucker D, Singh N, O'Malley B. Endocrine Society 2014 Laureate Awards. Horm Cancer. 2014 Oct; 5(5):339-55. PMID: 25091407.
      Citations:    Fields:    Translation:Humans
    154. Wang W, Bian K, Vallabhaneni S, Zhang B, Wu RC, O'Malley BW, Long W. ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expression. J Cell Physiol. 2014 Oct; 229(10):1529-37. PMID: 24585635.
      Citations: 16     Fields:    Translation:HumansCells
    155. Rechoum Y, Rovito D, Iacopetta D, Barone I, Andò S, Weigel NL, O'Malley BW, Brown PH, Fuqua SA. AR collaborates with ERa in aromatase inhibitor-resistant breast cancer. Breast Cancer Res Treat. 2014 Oct; 147(3):473-85. PMID: 25178514.
      Citations: 34     Fields:    Translation:HumansCells
    156. Tannour-Louet M, York B, Tang K, Stashi E, Bouguerra H, Zhou S, Yu H, Wong LJ, Stevens RD, Xu J, Newgard CB, O'Malley BW, Louet JF. Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis. Mol Endocrinol. 2014 Oct; 28(10):1707-18. PMID: 25148457.
      Citations: 3     Fields:    Translation:AnimalsCells
    157. Dasgupta S, O'Malley BW. Transcriptional coregulators: emerging roles of SRC family of coactivators in disease pathology. J Mol Endocrinol. 2014 Oct; 53(2):R47-59. PMID: 25024406.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    158. Hays T, Ma'ayan A, Clark NR, Tan CM, Teixeira A, Teixeira A, Choi JW, Burdis N, Jung SY, Bajaj AO, O'Malley BW, He JC, Hyink DP, Klotman PE. Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte. PLoS One. 2014; 9(6):e100660. PMID: 24949636.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    159. Stashi E, York B, O'Malley BW. Steroid receptor coactivators: servants and masters for control of systems metabolism. Trends Endocrinol Metab. 2014 Jul; 25(7):337-47. PMID: 24953190.
      Citations: 34     Fields:    Translation:HumansAnimals
    160. Feng Q, O'Malley BW. Nuclear receptor modulation--role of coregulators in selective estrogen receptor modulator (SERM) actions. Steroids. 2014 Nov; 90:39-43. PMID: 24945111.
      Citations: 10     Fields:    Translation:HumansAnimals
    161. Szwarc MM, Kommagani R, Jeong JW, Wu SP, Tsai SY, Tsai MJ, O'Malley BW, DeMayo FJ, Lydon JP. Perturbing the cellular levels of steroid receptor coactivator-2 impairs murine endometrial function. PLoS One. 2014; 9(6):e98664. PMID: 24905738.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    162. Bäck LJ, Mäkitie AA, O'Malley BW, Owen RP, Rinaldo A, Silver CE, Ferlito A. When is radiofrequency ablation not indicated in head and neck squamous cell carcinoma management? Eur Arch Otorhinolaryngol. 2015 May; 272(5):1045-6. PMID: 24880470.
      Citations:    Fields:    Translation:Humans
    163. Feng Q, Zhang Z, Shea MJ, Creighton CJ, Coarfa C, Hilsenbeck SG, Lanz R, He B, Wang L, Fu X, Nardone A, Song Y, Bradner J, Mitsiades N, Mitsiades CS, Osborne CK, Schiff R, O'Malley BW. An epigenomic approach to therapy for tamoxifen-resistant breast cancer. Cell Res. 2014 Jul; 24(7):809-19. PMID: 24874954.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    164. Reineke EL, Benham A, Soibam B, Stashi E, Taegtmeyer H, Entman ML, Schwartz RJ, O'Malley BW. Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function. J Biol Chem. 2014 Jun 20; 289(25):17721-31. PMID: 24811170.
      Citations: 9     Fields:    Translation:Animals
    165. Putluri N, Maity S, Kommagani R, Kommangani R, Creighton CJ, Putluri V, Chen F, Nanda S, Bhowmik SK, Terunuma A, Dorsey T, Nardone A, Fu X, Shaw C, Sarkar TR, Schiff R, Lydon JP, O'Malley BW, Ambs S, Das GM, Michailidis G, Sreekumar A. Pathway-centric integrative analysis identifies RRM2 as a prognostic marker in breast cancer associated with poor survival and tamoxifen resistance. Neoplasia. 2014 May; 16(5):390-402. PMID: 25016594.
      Citations: 26     Fields:    Translation:HumansCells
    166. Yan F, Yu Y, Chow DC, Palzkill T, Madoux F, Hodder P, Chase P, Griffin PR, O'Malley BW, Lonard DM. Identification of verrucarin a as a potent and selective steroid receptor coactivator-3 small molecule inhibitor. PLoS One. 2014; 9(4):e95243. PMID: 24743578.
      Citations: 18     Fields:    Translation:HumansCells
    167. Kommagani R, Szwarc MM, Kovanci E, Creighton CJ, O'Malley BW, Demayo FJ, Lydon JP. A murine uterine transcriptome, responsive to steroid receptor coactivator-2, reveals transcription factor 23 as essential for decidualization of human endometrial stromal cells. Biol Reprod. 2014 Apr; 90(4):75. PMID: 24571987.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    168. Han SJ, O'Malley BW. The dynamics of nuclear receptors and nuclear receptor coregulators in the pathogenesis of endometriosis. Hum Reprod Update. 2014 Jul-Aug; 20(4):467-84. PMID: 24634322.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    169. Zheng J, Nagda DA, Lajud SA, Kumar S, Mouchli A, Bezpalko O, O'Malley BW, Li D. Biliverdin's regulation of reactive oxygen species signalling leads to potent inhibition of proliferative and angiogenic pathways in head and neck cancer. Br J Cancer. 2014 Apr 15; 110(8):2116-22. PMID: 24569474.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    170. Kang YK, Jung SY, Qin J, Li C, Tsai SY, Tsai MJ, O'Malley BW. E2/Estrogen receptor/sjogren syndrome-associated autoantigen relieves coactivator activator-induced G1/S arrest to promote breast tumorigenicity. Mol Cell Biol. 2014 May; 34(9):1670-81. PMID: 24567374.
      Citations: 2     Fields:    Translation:HumansCells
    171. Stashi E, Lanz RB, Mao J, Michailidis G, Zhu B, Kettner NM, Putluri N, Reineke EL, Reineke LC, Dasgupta S, Dean A, Stevenson CR, Sivasubramanian N, Sreekumar A, Demayo F, York B, Fu L, O'Malley BW. SRC-2 is an essential coactivator for orchestrating metabolism and circadian rhythm. Cell Rep. 2014 Feb 27; 6(4):633-45. PMID: 24529706.
      Citations: 37     Fields:    Translation:AnimalsCells
    172. Motamed M, Rajapakshe KI, Hartig SM, Coarfa C, Moses RE, Lonard DM, O'Malley BW. Steroid receptor coactivator 1 is an integrator of glucose and NAD+/NADH homeostasis. Mol Endocrinol. 2014 Mar; 28(3):395-405. PMID: 24438340.
      Citations: 8     Fields:    Translation:HumansCells
    173. Wang Y, Lonard DM, Yu Y, Chow DC, Palzkill TG, Wang J, Qi R, Matzuk AJ, Song X, Madoux F, Hodder P, Chase P, Griffin PR, Zhou S, Liao L, Xu J, O'Malley BW. Bufalin is a potent small-molecule inhibitor of the steroid receptor coactivators SRC-3 and SRC-1. Cancer Res. 2014 Mar 01; 74(5):1506-1517. PMID: 24390736.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    174. Kommagani R, Szwarc MM, Kovanci E, Gibbons WE, Putluri N, Maity S, Creighton CJ, Sreekumar A, DeMayo FJ, Lydon JP, O'Malley BW. Acceleration of the glycolytic flux by steroid receptor coactivator-2 is essential for endometrial decidualization. PLoS Genet. 2013 Oct; 9(10):e1003900. PMID: 24204309.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    175. Savulescu D, Feng J, Ping YS, Mai O, Boehm U, He B, O'Malley BW, Melamed P. Gonadotropin-releasing hormone-regulated prohibitin mediates apoptosis of the gonadotrope cells. Mol Endocrinol. 2013 Nov; 27(11):1856-70. PMID: 24085822.
      Citations: 11     Fields:    Translation:AnimalsCells
    176. Owen RP, Lee JS, Silver CE, Bäck L, Beitler JJ, Rinaldo A, O'Malley BW, Haigentz M, Ferlito A. Radiofrequency ablation in advanced head and neck cancer. Eur Arch Otorhinolaryngol. 2014 Feb; 271(2):207-10. PMID: 24061569.
      Citations: 1     Fields:    Translation:Humans
    177. Dasgupta S, Lonard DM, O'Malley BW. Nuclear receptor coactivators: master regulators of human health and disease. Annu Rev Med. 2014; 65:279-92. PMID: 24111892.
      Citations: 77     Fields:    Translation:HumansCells
    178. Dong S, Jia C, Zhang S, Fan G, Li Y, Shan P, Sun L, Xiao W, Li L, Zheng Y, Liu J, Wei H, Hu C, Zhang W, Chin YE, Zhai Q, Li Q, Liu J, Jia F, Mo Q, Edwards DP, Huang S, Chan L, O'Malley BW, Li X, Wang C. The REG? proteasome regulates hepatic lipid metabolism through inhibition of autophagy. Cell Metab. 2013 Sep 03; 18(3):380-91. PMID: 24011073.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    179. Stashi E, Wang L, Mani SK, York B, O'Malley BW. Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences. Mol Endocrinol. 2013 Oct; 27(10):1776-87. PMID: 23927929.
      Citations: 9     Fields:    Translation:Animals
    180. Ramakrishnan VR, Lee JY, O'Malley BW, Palmer JN, Chiu AG. 18-FDG-PET in the initial staging of sinonasal malignancy. Laryngoscope. 2013 Dec; 123(12):2962-6. PMID: 23877974.
      Citations: 3     Fields:    Translation:Humans
    181. Foulds CE, Feng Q, Ding C, Bailey S, Hunsaker TL, Malovannaya A, Hamilton RA, Gates LA, Zhang Z, Li C, Chan D, Bajaj A, Callaway CG, Edwards DP, Lonard DM, Tsai SY, Tsai MJ, Qin J, O'Malley BW. Proteomic analysis of coregulators bound to ERa on DNA and nucleosomes reveals coregulator dynamics. Mol Cell. 2013 Jul 25; 51(2):185-99. PMID: 23850489.
      Citations: 64     Fields:    Translation:HumansCells
    182. Swisher-McClure S, Mitra N, Lin A, Ahn P, Wan F, O'Malley B, Weinstein GS, Bekelman JE. Risk of fatal cerebrovascular accidents after external beam radiation therapy for early-stage glottic laryngeal cancer. Head Neck. 2014 May; 36(5):611-6. PMID: 23595858.
      Citations: 16     Fields:    Translation:Humans
    183. Li L, Zhao D, Wei H, Yao L, Dang Y, Amjad A, Xu J, Liu J, Guo L, Li D, Li Z, Zuo D, Zhang Y, Liu J, Huang S, Jia C, Wang L, Wang Y, Xie Y, Luo J, Zhang B, Luo H, Donehower LA, Moses RE, Xiao J, O'Malley BW, Li X. REG? deficiency promotes premature aging via the casein kinase 1 pathway. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):11005-10. PMID: 23766372.
      Citations: 31     Fields:    Translation:Animals
    184. Bhat-Nakshatri P, Song EK, Collins NR, Uversky VN, Dunker AK, O'Malley BW, Geistlinger TR, Carroll JS, Brown M, Nakshatri H. Interplay between estrogen receptor and AKT in estradiol-induced alternative splicing. BMC Med Genomics. 2013 Jun 11; 6:21. PMID: 23758675.
      Citations: 10     Fields:    Translation:HumansCells
    185. Stoopler ET, Sia YW, Chalian AA, O'Malley BW, Alawi F. A rare presentation of multiple primary squamous cell carcinoma of the tongue in a patient with recurrent hepatitis C infection. Spec Care Dentist. 2014 Mar-Apr; 34(2):96-9. PMID: 24588494.
      Citations:    Fields:    Translation:Humans
    186. Geng C, He B, Xu L, Barbieri CE, Eedunuri VK, Chew SA, Zimmermann M, Bond R, Shou J, Li C, Blattner M, Lonard DM, Demichelis F, Coarfa C, Rubin MA, Zhou P, O'Malley BW, Mitsiades N. Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6997-7002. PMID: 23559371.
      Citations: 106     Fields:    Translation:HumansCells
    187. Redfern AD, Colley SM, Beveridge DJ, Ikeda N, Epis MR, Li X, Foulds CE, Stuart LM, Barker A, Russell VJ, Ramsay K, Kobelke SJ, Li X, Hatchell EC, Payne C, Giles KM, Messineo A, Gatignol A, Lanz RB, O'Malley BW, Leedman PJ. RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6536-41. PMID: 23550157.
      Citations: 44     Fields:    Translation:HumansCells
    188. O'Malley BW, Khan S. Elwood V. Jensen (1920-2012): father of the nuclear receptors. Proc Natl Acad Sci U S A. 2013 Mar 05; 110(10):3707-8. PMID: 23471960.
      Citations: 5     Fields:    Translation:HumansAnimals
    189. Yi P, Xia W, Wu RC, Lonard DM, Hung MC, O'Malley BW. SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. Genes Dev. 2013 Feb 01; 27(3):274-87. PMID: 23388826.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    190. York B, Sagen JV, Tsimelzon A, Louet JF, Chopra AR, Reineke EL, Zhou S, Stevens RD, Wenner BR, Ilkayeva O, Bain JR, Xu J, Hilsenbeck SG, Newgard CB, O'Malley BW. Research resource: tissue- and pathway-specific metabolomic profiles of the steroid receptor coactivator (SRC) family. Mol Endocrinol. 2013 Feb; 27(2):366-80. PMID: 23315938.
      Citations: 15     Fields:    Translation:Animals
    191. Stewart M, Chandra R, Chiu A, Hanna E, Kennedy D, Kraus D, Gleeson M, Levine P, Niparko J, O'Malley B, Rosenfeld R, Ruben R, Sataloff R, Smith R, Weber P. The value of resident presentations at scientific meetings. Otolaryngol Head Neck Surg. 2013 Jan; 148(1):5. PMID: 23243136.
      Citations:    
    192. Reineke EL, York B, Stashi E, Chen X, Tsimelzon A, Xu J, Newgard CB, Taffet GE, Taegtmeyer H, Entman ML, O'Malley BW. SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart. PLoS One. 2012; 7(12):e53395. PMID: 23300926.
      Citations: 15     Fields:    Translation:AnimalsCells
    193. Sánchez-Quiles V, Segura V, Bigaud E, He B, O'Malley BW, Santamaría E, Prieto J, Corrales FJ. Prohibitin-1 deficiency promotes inflammation and increases sensitivity to liver injury. J Proteomics. 2012 Oct 22; 75(18):5783-92. PMID: 22951295.
      Citations: 10     Fields:    Translation:AnimalsCells
    194. Liu SH, Rao DD, Nemunaitis J, Senzer N, Zhou G, Dawson D, Gingras MC, Wang Z, Gibbs R, Norman M, Templeton NS, Demayo FJ, O'Malley B, Sanchez R, Fisher WE, Brunicardi FC. PDX-1 is a therapeutic target for pancreatic cancer, insulinoma and islet neoplasia using a novel RNA interference platform. PLoS One. 2012; 7(8):e40452. PMID: 22905092.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    195. Han SJ, Hawkins SM, Begum K, Jung SY, Kovanci E, Qin J, Lydon JP, DeMayo FJ, O'Malley BW. A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis. Nat Med. 2012 Jul; 18(7):1102-11. PMID: 22660634.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    196. O'Malley BW, Malovannaya A, Qin J. Minireview: nuclear receptor and coregulator proteomics--2012 and beyond. Mol Endocrinol. 2012 Oct; 26(10):1646-50. PMID: 22745194.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    197. Lonard DM, O'Malley BW. Nuclear receptor coregulators: modulators of pathology and therapeutic targets. Nat Rev Endocrinol. 2012 Oct; 8(10):598-604. PMID: 22733267.
      Citations: 102     Fields:    Translation:HumansAnimals
    198. Liu A, Margaill I, Zhang S, Labombarda F, Coqueran B, Delespierre B, Liere P, Marchand-Leroux C, O'Malley BW, Lydon JP, De Nicola AF, Sitruk-Ware R, Mattern C, Plotkine M, Schumacher M, Guennoun R. Progesterone receptors: a key for neuroprotection in experimental stroke. Endocrinology. 2012 Aug; 153(8):3747-57. PMID: 22635678.
      Citations: 37     Fields:    Translation:AnimalsCells
    199. Moses RE, O'Malley BW. DNA transcription and repair: a confluence. J Biol Chem. 2012 Jul 06; 287(28):23266-70. PMID: 22605334.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    200. Park S, Yoon S, Zhao Y, Park SE, Liao L, Xu J, Lydon JP, DeMayo FJ, O'Malley BW, Bagchi MK, Katzenellenbogen BS. Uterine development and fertility are dependent on gene dosage of the nuclear receptor coregulator REA. Endocrinology. 2012 Aug; 153(8):3982-94. PMID: 22585830.
      Citations: 12     Fields:    Translation:AnimalsCells
    201. O'Donnell KA, Keng VW, York B, Reineke EL, Seo D, Fan D, Silverstein KA, Schrum CT, Xie WR, Mularoni L, Wheelan SJ, Torbenson MS, O'Malley BW, Largaespada DA, Boeke JD. A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer. Proc Natl Acad Sci U S A. 2012 May 22; 109(21):E1377-86. PMID: 22556267.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    202. York B, Reineke EL, Sagen JV, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, Stevens RD, Wenner BR, Ilkayeva O, Xu J, Newgard CB, O'Malley BW. Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. Cell Metab. 2012 May 02; 15(5):752-63. PMID: 22560224.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    203. Long W, Foulds CE, Qin J, Liu J, Ding C, Lonard DM, Solis LM, Wistuba II, Qin J, Tsai SY, Tsai MJ, O'Malley BW. ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion. J Clin Invest. 2012 May; 122(5):1869-80. PMID: 22505454.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    204. Wu MY, Fu J, Xu J, O'Malley BW, Wu RC. Steroid receptor coactivator 3 regulates autophagy in breast cancer cells through macrophage migration inhibitory factor. Cell Res. 2012 Jun; 22(6):1003-21. PMID: 22430150.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    205. Grosskopf CC, Kuperstein AS, O'Malley BW, Sollecito TP. Parapharyngeal space tumors: another consideration for otalgia and temporomandibular disorders. Head Neck. 2013 May; 35(5):E153-6. PMID: 22307772.
      Citations: 2     Fields:    Translation:Humans
    206. Hartmaier RJ, Richter AS, Gillihan RM, Sallit JZ, McGuire SE, Wang J, Lee AV, Osborne CK, O'Malley BW, Brown PH, Xu J, Skaar TC, Philips S, Rae JM, Azzouz F, Li L, Hayden J, Henry NL, Nguyen AT, Stearns V, Hayes DF, Flockhart DA, Oesterreich S. A SNP in steroid receptor coactivator-1 disrupts a GSK3ß phosphorylation site and is associated with altered tamoxifen response in bone. Mol Endocrinol. 2012 Feb; 26(2):220-7. PMID: 22174377.
      Citations: 9     Fields:    Translation:HumansCells
    207. Wang Y, Lonard DM, Yu Y, Chow DC, Palzkill TG, O'Malley BW. Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1. Mol Endocrinol. 2011 Dec; 25(12):2041-53. PMID: 22053001.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    208. Park S, Zhao Y, Yoon S, Xu J, Liao L, Lydon J, DeMayo F, O'Malley BW, Katzenellenbogen BS. Repressor of estrogen receptor activity (REA) is essential for mammary gland morphogenesis and functional activities: studies in conditional knockout mice. Endocrinology. 2011 Nov; 152(11):4336-49. PMID: 21862609.
      Citations: 12     Fields:    Translation:AnimalsCells
    209. Johnson AB, O'Malley BW. Steroid receptor coactivators 1, 2, and 3: critical regulators of nuclear receptor activity and steroid receptor modulator (SRM)-based cancer therapy. Mol Cell Endocrinol. 2012 Jan 30; 348(2):430-9. PMID: 21664237.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    210. Johnson AB, O'Malley BW. ERasing breast cancer resistance through the kinome. Nat Med. 2011 Jun; 17(6):660-1. PMID: 21647142.
      Citations: 8     Fields:    Translation:Humans
    211. Malovannaya A, Lanz RB, Jung SY, Bulynko Y, Le NT, Chan DW, Ding C, Shi Y, Yucer N, Krenciute G, Kim BJ, Li C, Chen R, Li W, Wang Y, O'Malley BW, Qin J. Analysis of the human endogenous coregulator complexome. Cell. 2011 May 27; 145(5):787-99. PMID: 21620140.
      Citations: 186     Fields:    Translation:HumansCells
    212. Li C, Ao J, Fu J, Lee DF, Xu J, Lonard D, O'Malley BW. Tumor-suppressor role for the SPOP ubiquitin ligase in signal-dependent proteolysis of the oncogenic co-activator SRC-3/AIB1. Oncogene. 2011 Oct 20; 30(42):4350-64. PMID: 21577200.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    213. Reddy SD, Rayala SK, Ohshiro K, Pakala SB, Kobori N, Dash P, Yun S, Qin J, O'Malley BW, Kumar R. Multiple coregulatory control of tyrosine hydroxylase gene transcription. Proc Natl Acad Sci U S A. 2011 Mar 08; 108(10):4200-5. PMID: 21368136.
      Citations: 16     Fields:    Translation:AnimalsCells
    214. Chopra AR, Kommagani R, Saha P, Louet JF, Salazar C, Song J, Jeong J, Finegold M, Viollet B, DeMayo F, Chan L, Moore DD, O'Malley BW. Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption. Cell Metab. 2011 Jan 05; 13(1):35-43. PMID: 21195347.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    215. He B, Kim TH, Kommagani R, Feng Q, Lanz RB, Jeong JW, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. Estrogen-regulated prohibitin is required for mouse uterine development and adult function. Endocrinology. 2011 Mar; 152(3):1047-56. PMID: 21209023.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    216. O'Malley BW. Cellular proteome, coregulators, endocrine system and the human brain: the Regulatory biology of humanism. Aging (Albany NY). 2011 Jan; 3(1):22-5. PMID: 21258135.
      Citations:    Fields:    Translation:HumansAnimals
    217. Bulynko YA, O'Malley BW. Nuclear receptor coactivators: structural and functional biochemistry. Biochemistry. 2011 Jan 25; 50(3):313-28. PMID: 21141906.
      Citations: 37     Fields:    Translation:HumansAnimals
    218. Louet JF, Chopra AR, Sagen JV, An J, York B, Tannour-Louet M, Saha PK, Stevens RD, Wenner BR, Ilkayeva OR, Bain JR, Zhou S, DeMayo F, Xu J, Newgard CB, O'Malley BW. The coactivator SRC-1 is an essential coordinator of hepatic glucose production. Cell Metab. 2010 Dec 01; 12(6):606-18. PMID: 21109193.
      Citations: 35     Fields:    Translation:AnimalsCells
    219. Lydon JP, O'Malley BW. Minireview: steroid receptor coactivator-3: a multifarious coregulator in mammary gland metastasis. Endocrinology. 2011 Jan; 152(1):19-25. PMID: 21047941.
      Citations: 23     Fields:    Translation:HumansCells
    220. York B, O'Malley BW. Steroid receptor coactivator (SRC) family: masters of systems biology. J Biol Chem. 2010 Dec 10; 285(50):38743-50. PMID: 20956538.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    221. McKenna NJ, O'Malley BW. SnapShot: NR coregulators. Cell. 2010 Oct 01; 143(1):172-172.e1. PMID: 20887900.
      Citations: 6     Fields:    Translation:HumansAnimals
    222. McKenna NJ, O'Malley BW. SnapShot: Nuclear receptors II. Cell. 2010 Sep 17; 142(6):986.e1. PMID: 20850017.
      Citations:    Fields:    Translation:HumansAnimalsCells
    223. McKenna NJ, O'Malley BW. SnapShot: Nuclear receptors I. Cell. 2010 Sep 03; 142(5):822-822.e1. PMID: 20813267.
      Citations: 6     Fields:    Translation:HumansAnimals
    224. Brisken C, O'Malley B. Hormone action in the mammary gland. Cold Spring Harb Perspect Biol. 2010 Dec; 2(12):a003178. PMID: 20739412.
      Citations: 144     Fields:    Translation:Animals
    225. Quon H, O'Malley BW, Weinstein GS. Transoral robotic surgery and a paradigm shift in the management of oropharyngeal squamous cell carcinoma. J Robot Surg. 2010 Aug; 4(2):79-86. PMID: 27628771.
      Citations:    Fields:    
    226. Long W, O'Malley BW. Crosstalk among nuclear receptor coactivators and a membrane receptor promotes tumor cell growth and migration. Cell Cycle. 2010 Jun 15; 9(12):2269-70. PMID: 20519947.
      Citations: 1     
    227. York B, Yu C, Sagen JV, Liu Z, Nikolai BC, Wu RC, Finegold M, Xu J, O'Malley BW. Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):11122-7. PMID: 20534466.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    228. O'Malley BW. Masters of the genome. Nat Rev Mol Cell Biol. 2010 May; 11(5):311. PMID: 20422740.
      Citations: 6     Fields:    
    229. Foulds CE, Tsimelzon A, Long W, Le A, Tsai SY, Tsai MJ, O'Malley BW. Research resource: expression profiling reveals unexpected targets and functions of the human steroid receptor RNA activator (SRA) gene. Mol Endocrinol. 2010 May; 24(5):1090-105. PMID: 20219889.
      Citations: 31     Fields:    Translation:HumansCells
    230. Lanz RB, Bulynko Y, Malovannaya A, Labhart P, Wang L, Li W, Qin J, Harper M, O'Malley BW. Global characterization of transcriptional impact of the SRC-3 coregulator. Mol Endocrinol. 2010 Apr; 24(4):859-72. PMID: 20181721.
      Citations: 35     Fields:    Translation:HumansCells
    231. Fu X, Yucer N, Liu S, Li M, Yi P, Mu JJ, Yang T, Chu J, Jung SY, O'Malley BW, Gu W, Qin J, Wang Y. RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proc Natl Acad Sci U S A. 2010 Mar 09; 107(10):4579-84. PMID: 20173098.
      Citations: 33     Fields:    Translation:HumansCells
    232. Long W, Yi P, Amazit L, LaMarca HL, Ashcroft F, Kumar R, Mancini MA, Tsai SY, Tsai MJ, O'Malley BW. SRC-3Delta4 mediates the interaction of EGFR with FAK to promote cell migration. Mol Cell. 2010 Feb 12; 37(3):321-32. PMID: 20159552.
      Citations: 75     Fields:    Translation:HumansAnimalsCells
    233. Malovannaya A, Li Y, Bulynko Y, Jung SY, Wang Y, Lanz RB, O'Malley BW, Qin J. Streamlined analysis schema for high-throughput identification of endogenous protein complexes. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2431-6. PMID: 20133760.
      Citations: 63     Fields:    Translation:HumansCells
    234. Stanisic V, Lonard DM, O'Malley BW. Modulation of steroid hormone receptor activity. Prog Brain Res. 2010; 181:153-76. PMID: 20478437.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    235. Stanišic V, Lonard DM, O'Malley BW. Estrogen receptor-a: molecular mechanisms and interactions with the ubiquitin proteasome system. Horm Mol Biol Clin Investig. 2010 Jan; 1(1):1-9. PMID: 25961966.
      Citations: 1     Fields:    
    236. Han SJ, O'Malley BW, DeMayo FJ. An estrogen receptor alpha activity indicator model in mice. Genesis. 2009 Dec; 47(12):815-24. PMID: 19882671.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    237. Malik S, Jiang S, Garee JP, Verdin E, Lee AV, O'Malley BW, Zhang M, Belaguli NS, Oesterreich S. Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM. Mol Cell Biol. 2010 Jan; 30(2):399-412. PMID: 19917725.
      Citations: 37     Fields:    Translation:HumansCells
    238. Yamagata K, Fujiyama S, Ito S, Ueda T, Murata T, Naitou M, Takeyama K, Minami Y, O'Malley BW, Kato S. Maturation of microRNA is hormonally regulated by a nuclear receptor. Mol Cell. 2009 Oct 23; 36(2):340-7. PMID: 19854141.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    239. Lonard DM, Kumar R, O'Malley BW. Minireview: the SRC family of coactivators: an entrée to understanding a subset of polygenic diseases? Mol Endocrinol. 2010 Feb; 24(2):279-85. PMID: 19846539.
      Citations: 19     Fields:    Translation:HumansAnimals
    240. O'Malley BW, Kumar R. Nuclear receptor coregulators in cancer biology. Cancer Res. 2009 Nov 01; 69(21):8217-22. PMID: 19843848.
      Citations: 52     Fields:    Translation:HumansAnimals
    241. Feng Q, He B, Jung SY, Song Y, Qin J, Tsai SY, Tsai MJ, O'Malley BW. Biochemical control of CARM1 enzymatic activity by phosphorylation. J Biol Chem. 2009 Dec 25; 284(52):36167-36174. PMID: 19843527.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    242. Lonard DM, O'Malley BW. Emerging roles of the ubiquitin proteasome system in nuclear hormone receptor signaling. Prog Mol Biol Transl Sci. 2009; 87:117-35. PMID: 20374703.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    243. Xu J, Wu RC, O'Malley BW. Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nat Rev Cancer. 2009 Sep; 9(9):615-30. PMID: 19701241.
      Citations: 241     Fields:    Translation:HumansAnimalsCells
    244. Mödder UI, Monroe DG, Fraser DG, Spelsberg TC, Rosen CJ, Géhin M, Chambon P, O'Malley BW, Khosla S. Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2. J Biol Chem. 2009 Jul 10; 284(28):18767-77. PMID: 19423703.
      Citations: 15     Fields:    Translation:AnimalsCells
    245. McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW. Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol. 2009 Jun; 23(6):740-6. PMID: 19423650.
      Citations: 56     Fields:    Translation:Cells
    246. Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH. Foxa2-dependent hepatic gene regulatory networks depend on physiological state. Physiol Genomics. 2009 Jul 09; 38(2):186-95. PMID: 19417011.
      Citations: 12     Fields:    Translation:AnimalsCells
    247. Stanišic V, Malovannaya A, Qin J, Lonard DM, O'Malley BW. OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity. J Biol Chem. 2009 Jun 12; 284(24):16135-16145. PMID: 19383985.
      Citations: 33     Fields:    Translation:HumansCells
    248. O'Malley BW. The "fourth dimension" of gene transcription. Mol Endocrinol. 2009 May; 23(5):587-9. PMID: 19221049.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    249. Wang S, Yuan Y, Liao L, Kuang SQ, Tien JC, O'Malley BW, Xu J. Disruption of the SRC-1 gene in mice suppresses breast cancer metastasis without affecting primary tumor formation. Proc Natl Acad Sci U S A. 2009 Jan 06; 106(1):151-6. PMID: 19109434.
      Citations: 61     Fields:    Translation:Animals
    250. Chopra AR, Louet JF, Saha P, An J, Demayo F, Xu J, York B, Karpen S, Finegold M, Moore D, Chan L, Newgard CB, O'Malley BW. Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease. Science. 2008 Nov 28; 322(5906):1395-9. PMID: 19039140.
      Citations: 94     Fields:    Translation:AnimalsCells
    251. Han SJ, Lonard DM, O'Malley BW. Multi-modulation of nuclear receptor coactivators through posttranslational modifications. Trends Endocrinol Metab. 2009 Jan; 20(1):8-15. PMID: 19019695.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    252. Coste A, Louet JF, Lagouge M, Lerin C, Antal MC, Meziane H, Schoonjans K, Puigserver P, O'Malley BW, Auwerx J. The genetic ablation of SRC-3 protects against obesity and improves insulin sensitivity by reducing the acetylation of PGC-1{alpha}. Proc Natl Acad Sci U S A. 2008 Nov 04; 105(44):17187-92. PMID: 18957541.
      Citations: 88     Fields:    Translation:AnimalsCells
    253. O'Malley B. The Year in Basic Science: nuclear receptors and coregulators. Mol Endocrinol. 2008 Dec; 22(12):2751-8. PMID: 18845672.
      Citations: 12     Fields:    Translation:HumansAnimals
    254. Kang YK, Schiff R, Ko L, Wang T, Tsai SY, Tsai MJ, O'Malley BW. Dual roles for coactivator activator and its counterbalancing isoform coactivator modulator in human kidney cell tumorigenesis. Cancer Res. 2008 Oct 01; 68(19):7887-96. PMID: 18829545.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    255. Li C, Liang YY, Feng XH, Tsai SY, Tsai MJ, O'Malley BW. Essential phosphatases and a phospho-degron are critical for regulation of SRC-3/AIB1 coactivator function and turnover. Mol Cell. 2008 Sep 26; 31(6):835-49. PMID: 18922467.
      Citations: 37     Fields:    Translation:HumansCells
    256. O'Malley BW, McKenna NJ. Coactivators and corepressors: what's in a name? Mol Endocrinol. 2008 Oct; 22(10):2213-4. PMID: 18701638.
      Citations: 14     Fields:    Translation:Humans
    257. Qin L, Liao L, Redmond A, Young L, Yuan Y, Chen H, O'Malley BW, Xu J. The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression. Mol Cell Biol. 2008 Oct; 28(19):5937-50. PMID: 18644862.
      Citations: 103     Fields:    Translation:HumansAnimalsCells
    258. O'Malley BW, Qin J, Lanz RB. Cracking the coregulator codes. Curr Opin Cell Biol. 2008 Jun; 20(3):310-5. PMID: 18499426.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    259. Fereshteh MP, Tilli MT, Kim SE, Xu J, O'Malley BW, Wellstein A, Furth PA, Riegel AT. The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice. Cancer Res. 2008 May 15; 68(10):3697-706. PMID: 18483252.
      Citations: 57     Fields:    Translation:AnimalsCells
    260. Lonard DM, O'Malley BW. Gene transcription: two worlds merged. Nature. 2008 Apr 24; 452(7190):946-7. PMID: 18432236.
      Citations: 3     Fields:    Translation:Cells
    261. Lonard DM, O'Malley BW. SRC-3 transcription-coupled activation, degradation, and the ubiquitin clock: is there enough coactivator to go around in cells? Sci Signal. 2008 Apr 01; 1(13):pe16. PMID: 18385039.
      Citations: 22     Fields:    Translation:HumansCells
    262. Yi P, Feng Q, Amazit L, Lonard DM, Tsai SY, Tsai MJ, O'Malley BW. Atypical protein kinase C regulates dual pathways for degradation of the oncogenic coactivator SRC-3/AIB1. Mol Cell. 2008 Feb 29; 29(4):465-76. PMID: 18313384.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    263. Rickard DJ, Iwaniec UT, Evans G, Hefferan TE, Hunter JC, Waters KM, Lydon JP, O'Malley BW, Khosla S, Spelsberg TC, Turner RT. Bone growth and turnover in progesterone receptor knockout mice. Endocrinology. 2008 May; 149(5):2383-90. PMID: 18276762.
      Citations: 18     Fields:    Translation:AnimalsCells
    264. Loehberg CR, Thompson T, Kastan MB, Maclean KH, Edwards DG, Kittrell FS, Medina D, Conneely OM, O'Malley BW. Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis. Cancer Res. 2007 Dec 15; 67(24):12026-33. PMID: 18089834.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    265. Mödder UI, Sanyal A, Xu J, O'Malley BW, Spelsberg TC, Khosla S. The skeletal response to estrogen is impaired in female but not in male steroid receptor coactivator (SRC)-1 knock out mice. Bone. 2008 Feb; 42(2):414-21. PMID: 18055287.
      Citations: 11     Fields:    Translation:Animals
    266. He B, Feng Q, Mukherjee A, Lonard DM, DeMayo FJ, Katzenellenbogen BS, Lydon JP, O'Malley BW. A repressive role for prohibitin in estrogen signaling. Mol Endocrinol. 2008 Feb; 22(2):344-60. PMID: 17932104.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    267. Jordan VC, O'Malley BW. Selective estrogen-receptor modulators and antihormonal resistance in breast cancer. J Clin Oncol. 2007 Dec 20; 25(36):5815-24. PMID: 17893378.
      Citations: 120     Fields:    Translation:Humans
    268. Lonard DM, O'malley BW. Nuclear receptor coregulators: judges, juries, and executioners of cellular regulation. Mol Cell. 2007 Sep 07; 27(5):691-700. PMID: 17803935.
      Citations: 186     Fields:    Translation:HumansCells
    269. Amazit L, Pasini L, Szafran AT, Berno V, Wu RC, Mielke M, Jones ED, Mancini MG, Hinojos CA, O'Malley BW, Mancini MA. Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Mol Cell Biol. 2007 Oct; 27(19):6913-32. PMID: 17646391.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    270. Louet JF, O'Malley BW. Coregulators in adipogenesis: what could we learn from the SRC (p160) coactivator family? Cell Cycle. 2007 Oct 15; 6(20):2448-52. PMID: 17704643.
      Citations: 19     Translation:HumansAnimalsCells
    271. Lonard DM, Lanz RB, O'Malley BW. Nuclear receptor coregulators and human disease. Endocr Rev. 2007 Aug; 28(5):575-87. PMID: 17609497.
      Citations: 128     Fields:    Translation:HumansAnimals
    272. Li X, Amazit L, Long W, Lonard DM, Monaco JJ, O'Malley BW. Ubiquitin- and ATP-independent proteolytic turnover of p21 by the REGgamma-proteasome pathway. Mol Cell. 2007 Jun 22; 26(6):831-42. PMID: 17588518.
      Citations: 121     Fields:    Translation:HumansAnimalsCells
    273. Wu RC, Feng Q, Lonard DM, O'Malley BW. SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. Cell. 2007 Jun 15; 129(6):1125-40. PMID: 17574025.
      Citations: 118     Fields:    Translation:HumansCells
    274. Jeong JW, Lee KY, Han SJ, Aronow BJ, Lydon JP, O'Malley BW, DeMayo FJ. The p160 steroid receptor coactivator 2, SRC-2, regulates murine endometrial function and regulates progesterone-independent and -dependent gene expression. Endocrinology. 2007 Sep; 148(9):4238-50. PMID: 17556502.
      Citations: 30     Fields:    Translation:Animals
    275. Fukuda T, Yamagata K, Fujiyama S, Matsumoto T, Koshida I, Yoshimura K, Mihara M, Naitou M, Endoh H, Nakamura T, Akimoto C, Yamamoto Y, Katagiri T, Foulds C, Takezawa S, Kitagawa H, Takeyama K, O'Malley BW, Kato S. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol. 2007 May; 9(5):604-11. PMID: 17435748.
      Citations: 192     Fields:    Translation:AnimalsCells
    276. Meng Q, Rayala SK, Gururaj AE, Talukder AH, O'Malley BW, Kumar R. Signaling-dependent and coordinated regulation of transcription, splicing, and translation resides in a single coregulator, PCBP1. Proc Natl Acad Sci U S A. 2007 Apr 03; 104(14):5866-71. PMID: 17389360.
      Citations: 45     Fields:    Translation:HumansCells
    277. Yu C, York B, Wang S, Feng Q, Xu J, O'Malley BW. An essential function of the SRC-3 coactivator in suppression of cytokine mRNA translation and inflammatory response. Mol Cell. 2007 Mar 09; 25(5):765-78. PMID: 17349961.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    278. Auboeuf D, Batsché E, Dutertre M, Muchardt C, O'Malley BW. Coregulators: transducing signal from transcription to alternative splicing. Trends Endocrinol Metab. 2007 Apr; 18(3):122-9. PMID: 17320409.
      Citations: 25     Fields:    Translation:HumansCells
    279. Han SJ, Tsai SY, Tsai MJ, O'Malley BW. Distinct temporal and spatial activities of RU486 on progesterone receptor function in reproductive organs of ovariectomized mice. Endocrinology. 2007 May; 148(5):2471-86. PMID: 17303655.
      Citations: 11     Fields:    Translation:AnimalsCells
    280. O'Malley BW. Coregulators: from whence came these "master genes". Mol Endocrinol. 2007 May; 21(5):1009-13. PMID: 17284664.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    281. Han SJ, DeMayo FJ, O'Malley BW. Dynamic regulation of progesterone receptor activity in female reproductive tissues. Ernst Schering Found Symp Proc. 2007; (1):25-43. PMID: 18543433.
      Citations: 4     Fields:    Translation:HumansAnimals
    282. Mukherjee A, Amato P, Craig-Allred D, DeMayo FJ, O'Malley BW, Lydon JP. Steroid receptor coactivator 2: an essential coregulator of progestin-induced uterine and mammary morphogenesis. Ernst Schering Found Symp Proc. 2007; (1):55-76. PMID: 18540568.
      Citations: 2     Fields:    Translation:HumansAnimals
    283. Li C, Wu RC, Amazit L, Tsai SY, Tsai MJ, O'Malley BW. Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover. Mol Cell Biol. 2007 Feb; 27(4):1296-308. PMID: 17158932.
      Citations: 25     Fields:    Translation:HumansCells
    284. Louet JF, Coste A, Amazit L, Tannour-Louet M, Wu RC, Tsai SY, Tsai MJ, Auwerx J, O'Malley BW. Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17868-73. PMID: 17098861.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    285. Mussi P, Liao L, Park SE, Ciana P, Maggi A, Katzenellenbogen BS, Xu J, O'Malley BW. Haploinsufficiency of the corepressor of estrogen receptor activity (REA) enhances estrogen receptor function in the mammary gland. Proc Natl Acad Sci U S A. 2006 Nov 07; 103(45):16716-21. PMID: 17065319.
      Citations: 23     Fields:    Translation:AnimalsCells
    286. Mukherjee A, Amato P, Allred DC, Fernandez-Valdivia R, Nguyen J, O'Malley BW, DeMayo FJ, Lydon JP. Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: insights from the mouse--implications for the human. J Steroid Biochem Mol Biol. 2006 Dec; 102(1-5):22-31. PMID: 17045797.
      Citations: 11     Fields:    Translation:HumansAnimals
    287. O'Malley BW. Molecular biology. Little molecules with big goals. Science. 2006 Sep 22; 313(5794):1749-50. PMID: 16990541.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    288. Mukherjee A, Soyal SM, Fernandez-Valdivia R, Gehin M, Chambon P, Demayo FJ, Lydon JP, O'Malley BW. Steroid receptor coactivator 2 is critical for progesterone-dependent uterine function and mammary morphogenesis in the mouse. Mol Cell Biol. 2006 Sep; 26(17):6571-83. PMID: 16914740.
      Citations: 56     Fields:    Translation:AnimalsCells
    289. Feng Q, Yi P, Wong J, O'Malley BW. Signaling within a coactivator complex: methylation of SRC-3/AIB1 is a molecular switch for complex disassembly. Mol Cell Biol. 2006 Nov; 26(21):7846-57. PMID: 16923966.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    290. Mussi P, Yu C, O'Malley BW, Xu J. Stimulation of steroid receptor coactivator-3 (SRC-3) gene overexpression by a positive regulatory loop of E2F1 and SRC-3. Mol Endocrinol. 2006 Dec; 20(12):3105-19. PMID: 16916939.
      Citations: 37     Fields:    Translation:HumansCells
    291. Han SJ, Jung SY, Malovannaya A, Kim T, Lanz RB, Qin J, O'Malley BW. A scoring system for the follow up study of nuclear receptor coactivator complexes. Nucl Recept Signal. 2006; 4:e014. PMID: 16862220.
      Citations: 5     Fields:    
    292. Dhananjayan SC, Ramamoorthy S, Khan OY, Ismail A, Sun J, Slingerland J, O'Malley BW, Nawaz Z. WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors. Mol Endocrinol. 2006 Oct; 20(10):2343-54. PMID: 16772533.
      Citations: 38     Fields:    Translation:HumansCells
    293. Hatchell EC, Colley SM, Beveridge DJ, Epis MR, Stuart LM, Giles KM, Redfern AD, Miles LE, Barker A, MacDonald LM, Arthur PG, Lui JC, Golding JL, McCulloch RK, Metcalf CB, Wilce JA, Wilce MC, Lanz RB, O'Malley BW, Leedman PJ. SLIRP, a small SRA binding protein, is a nuclear receptor corepressor. Mol Cell. 2006 Jun 09; 22(5):657-68. PMID: 16762838.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    294. Lonard DM, O'Malley BW. The expanding cosmos of nuclear receptor coactivators. Cell. 2006 May 05; 125(3):411-4. PMID: 16678083.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    295. Coste A, Antal MC, Chan S, Kastner P, Mark M, O'Malley BW, Auwerx J. Absence of the steroid receptor coactivator-3 induces B-cell lymphoma. EMBO J. 2006 Jun 07; 25(11):2453-64. PMID: 16675958.
      Citations: 31     Fields:    Translation:AnimalsCells
    296. Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW, Chatterjee SK. Tumor metastasis in an orthotopic murine model of head and neck cancer: possible role of TGF-beta 1 secreted by the tumor cells. J Cell Biochem. 2006 Apr 01; 97(5):1036-51. PMID: 16294321.
      Citations: 17     Fields:    Translation:AnimalsCellsPHPublic Health
    297. Frye CA, Sumida K, Lydon JP, O'Malley BW, Pfaff DW. Mid-aged and aged wild-type and progestin receptor knockout (PRKO) mice demonstrate rapid progesterone and 3alpha,5alpha-THP-facilitated lordosis. Psychopharmacology (Berl). 2006 May; 185(4):423-32. PMID: 16544163.
      Citations: 23     Fields:    Translation:Animals
    298. Frye CA, Sumida K, Dudek BC, Harney JP, Lydon JP, O'Malley BW, Pfaff DW, Rhodes ME. Progesterone's effects to reduce anxiety behavior of aged mice do not require actions via intracellular progestin receptors. Psychopharmacology (Berl). 2006 Jun; 186(3):312-22. PMID: 16538472.
      Citations: 35     Fields:    Translation:Animals
    299. Woolley SC, O'Malley B, Lydon J, Crews D. Genotype differences in behavior and tyrosine hydroxylase expression between wild-type and progesterone receptor knockout mice. Behav Brain Res. 2006 Feb 28; 167(2):197-204. PMID: 16413068.
      Citations: 6     Fields:    Translation:Animals
    300. Li X, Lonard DM, Jung SY, Malovannaya A, Feng Q, Qin J, Tsai SY, Tsai MJ, O'Malley BW. The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome. Cell. 2006 Jan 27; 124(2):381-92. PMID: 16439211.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    301. Jeong JW, Kwak I, Lee KY, White LD, Wang XP, Brunicardi FC, O'Malley BW, DeMayo FJ. The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism. Mol Endocrinol. 2006 May; 20(5):1138-52. PMID: 16423883.
      Citations: 36     Fields:    Translation:Animals
    302. Winnay JN, Xu J, O'Malley BW, Hammer GD. Steroid receptor coactivator-1-deficient mice exhibit altered hypothalamic-pituitary-adrenal axis function. Endocrinology. 2006 Mar; 147(3):1322-32. PMID: 16339206.
      Citations: 22     Fields:    Translation:AnimalsCells
    303. Yi P, Wu RC, Sandquist J, Wong J, Tsai SY, Tsai MJ, Means AR, O'Malley BW. Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol. 2005 Nov; 25(21):9687-99. PMID: 16227615.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    304. Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW, Chatterjee SK. Inhibition of NK cell activity through TGF-beta 1 by down-regulation of NKG2D in a murine model of head and neck cancer. J Immunol. 2005 Oct 15; 175(8):5541-50. PMID: 16210663.
      Citations: 58     Fields:    Translation:AnimalsCells
    305. Schillinger KJ, Tsai SY, Taffet GE, Reddy AK, Marian AJ, Entman ML, Oka K, Chan L, O'Malley BW. Regulatable atrial natriuretic peptide gene therapy for hypertension. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):13789-94. PMID: 16162668.
      Citations: 18     Fields:    Translation:AnimalsCells
    306. Hockstein NG, Weinstein GS, O'malley BW. Maintenance of hemostasis in transoral robotic surgery. ORL J Otorhinolaryngol Relat Spec. 2005; 67(4):220-4. PMID: 16145284.
      Citations: 9     Fields:    Translation:Animals
    307. Han SJ, DeMayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator (SRC)-1 and SRC-3 differentially modulate tissue-specific activation functions of the progesterone receptor. Mol Endocrinol. 2006 Jan; 20(1):45-55. PMID: 16141356.
      Citations: 41     Fields:    Translation:AnimalsCells
    308. Kuang SQ, Liao L, Wang S, Medina D, O'Malley BW, Xu J. Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis. Cancer Res. 2005 Sep 01; 65(17):7993-8002. PMID: 16140972.
      Citations: 55     Fields:    Translation:AnimalsCells
    309. Han SJ, Jeong J, Demayo FJ, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Dynamic cell type specificity of SRC-1 coactivator in modulating uterine progesterone receptor function in mice. Mol Cell Biol. 2005 Sep; 25(18):8150-65. PMID: 16135805.
      Citations: 16     Fields:    Translation:AnimalsCells
    310. Zheng FF, Wu RC, Smith CL, O'Malley BW. Rapid estrogen-induced phosphorylation of the SRC-3 coactivator occurs in an extranuclear complex containing estrogen receptor. Mol Cell Biol. 2005 Sep; 25(18):8273-84. PMID: 16135815.
      Citations: 39     Fields:    Translation:HumansCells
    311. Ying H, Furuya F, Willingham MC, Xu J, O'Malley BW, Cheng SY. Dual functions of the steroid hormone receptor coactivator 3 in modulating resistance to thyroid hormone. Mol Cell Biol. 2005 Sep; 25(17):7687-95. PMID: 16107715.
      Citations: 11     Fields:    Translation:Cells
    312. McKenna NJ, O'Malley BW. Teaching resources. An interactive course in nuclear receptor signaling: concepts and models. Sci STKE. 2005 Aug 30; 2005(299):tr22. PMID: 16131668.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    313. Dasgupta S, Bhattacharya-Chatterjee M, O'Malley BW, Chatterjee SK. Recombinant vaccinia virus expressing interleukin-2 invokes anti-tumor cellular immunity in an orthotopic murine model of head and neck squamous cell carcinoma. Mol Ther. 2006 Jan; 13(1):183-93. PMID: 16125469.
      Citations: 9     Fields:    Translation:AnimalsCells
    314. Jung SY, Malovannaya A, Wei J, O'Malley BW, Qin J. Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes. Mol Endocrinol. 2005 Oct; 19(10):2451-65. PMID: 16051665.
      Citations: 58     Fields:    Translation:HumansCells
    315. Margolis RN, Evans RM, O'Malley BW. The Nuclear Receptor Signaling Atlas: development of a functional atlas of nuclear receptors. Mol Endocrinol. 2005 Oct; 19(10):2433-6. PMID: 16051673.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    316. Schneider JS, Burgess C, Sleiter NC, DonCarlos LL, Lydon JP, O'Malley B, Levine JE. Enhanced sexual behaviors and androgen receptor immunoreactivity in the male progesterone receptor knockout mouse. Endocrinology. 2005 Oct; 146(10):4340-8. PMID: 16002522.
      Citations: 22     Fields:    Translation:Animals
    317. Auboeuf D, Dowhan DH, Dutertre M, Martin N, Berget SM, O'Malley BW. A subset of nuclear receptor coregulators act as coupling proteins during synthesis and maturation of RNA transcripts. Mol Cell Biol. 2005 Jul; 25(13):5307-16. PMID: 15964789.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    318. Ye X, Han SJ, Tsai SY, DeMayo FJ, Xu J, Tsai MJ, O'Malley BW. Roles of steroid receptor coactivator (SRC)-1 and transcriptional intermediary factor (TIF) 2 in androgen receptor activity in mice. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9487-92. PMID: 15983373.
      Citations: 18     Fields:    Translation:Animals
    319. Apostolakis EM, Riherd DN, O'Malley BW. PAC1 receptors mediate pituitary adenylate cyclase-activating polypeptide- and progesterone-facilitated receptivity in female rats. Mol Endocrinol. 2005 Nov; 19(11):2798-811. PMID: 15976009.
      Citations: 9     Fields:    Translation:Animals
    320. O'Malley BW. A life-long search for the molecular pathways of steroid hormone action. Mol Endocrinol. 2005 Jun; 19(6):1402-11. PMID: 15914709.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    321. Masuhiro Y, Mezaki Y, Sakari M, Takeyama K, Yoshida T, Inoue K, Yanagisawa J, Hanazawa S, O'malley BW, Kato S. Splicing potentiation by growth factor signals via estrogen receptor phosphorylation. Proc Natl Acad Sci U S A. 2005 Jun 07; 102(23):8126-31. PMID: 15919818.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    322. Wu RC, Smith CL, O'Malley BW. Transcriptional regulation by steroid receptor coactivator phosphorylation. Endocr Rev. 2005 May; 26(3):393-9. PMID: 15814849.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    323. Park KJ, Krishnan V, O'Malley BW, Yamamoto Y, Gaynor RB. Formation of an IKKalpha-dependent transcription complex is required for estrogen receptor-mediated gene activation. Mol Cell. 2005 Apr 01; 18(1):71-82. PMID: 15808510.
      Citations: 74     Fields:    Translation:HumansCells
    324. Lonard DM, O'Malley BW. Expanding functional diversity of the coactivators. Trends Biochem Sci. 2005 Mar; 30(3):126-32. PMID: 15752984.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    325. Park SE, Xu J, Frolova A, Liao L, O'Malley BW, Katzenellenbogen BS. Genetic deletion of the repressor of estrogen receptor activity (REA) enhances the response to estrogen in target tissues in vivo. Mol Cell Biol. 2005 Mar; 25(5):1989-99. PMID: 15713652.
      Citations: 43     Fields:    Translation:AnimalsCells
    326. Dennis AP, Lonard DM, Nawaz Z, O'Malley BW. Inhibition of the 26S proteasome blocks progesterone receptor-dependent transcription through failed recruitment of RNA polymerase II. J Steroid Biochem Mol Biol. 2005 Mar; 94(4):337-46. PMID: 15857753.
      Citations: 25     Fields:    Translation:HumansCells
    327. Dennis AP, O'Malley BW. Rush hour at the promoter: how the ubiquitin-proteasome pathway polices the traffic flow of nuclear receptor-dependent transcription. J Steroid Biochem Mol Biol. 2005 Feb; 93(2-5):139-51. PMID: 15860256.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    328. Dowhan DH, Hong EP, Auboeuf D, Dennis AP, Wilson MM, Berget SM, O'Malley BW. Steroid hormone receptor coactivation and alternative RNA splicing by U2AF65-related proteins CAPERalpha and CAPERbeta. Mol Cell. 2005 Feb 04; 17(3):429-39. PMID: 15694343.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    329. Labhart P, Karmakar S, Salicru EM, Egan BS, Alexiadis V, O'Malley BW, Smith CL. Identification of target genes in breast cancer cells directly regulated by the SRC-3/AIB1 coactivator. Proc Natl Acad Sci U S A. 2005 Feb 01; 102(5):1339-44. PMID: 15677324.
      Citations: 61     Fields:    Translation:HumansCells
    330. Reddy DS, O'Malley BW, Rogawski MA. Anxiolytic activity of progesterone in progesterone receptor knockout mice. Neuropharmacology. 2005 Jan; 48(1):14-24. PMID: 15617723.
      Citations: 48     Fields:    Translation:Animals
    331. Nishihara E, O'Malley BW, Xu J. Nuclear receptor coregulators are new players in nervous system development and function. Mol Neurobiol. 2004 Dec; 30(3):307-25. PMID: 15655254.
      Citations: 10     Fields:    Translation:HumansAnimals
    332. O'Malley BW. Results of a search for the mechanisms of steroid receptor regulation of gene expression. Ann N Y Acad Sci. 2004 Dec; 1038:80-7. PMID: 15838100.
      Citations: 2     Fields:    Translation:AnimalsCells
    333. Wu HY, Hamamori Y, Xu J, Chang SC, Saluna T, Chang MF, O'Malley BW, Kedes L. Nuclear hormone receptor coregulator GRIP1 suppresses, whereas SRC1A and p/CIP coactivate, by domain-specific binding of MyoD. J Biol Chem. 2005 Feb 04; 280(5):3129-37. PMID: 15563453.
      Citations: 9     Fields:    Translation:AnimalsCells
    334. Li X, Lonard DM, O'Malley BW. A contemporary understanding of progesterone receptor function. Mech Ageing Dev. 2004 Oct-Nov; 125(10-11):669-78. PMID: 15541762.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    335. Verma S, Ismail A, Gao X, Fu G, Li X, O'Malley BW, Nawaz Z. The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors. Mol Cell Biol. 2004 Oct; 24(19):8716-26. PMID: 15367689.
      Citations: 26     Fields:    Translation:HumansCells
    336. Wu RC, Qin J, Yi P, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell. 2004 Sep 24; 15(6):937-49. PMID: 15383283.
      Citations: 129     Fields:    Translation:HumansAnimalsCells
    337. Mark M, Yoshida-Komiya H, Gehin M, Liao L, Tsai MJ, O'Malley BW, Chambon P, Xu J. Partially redundant functions of SRC-1 and TIF2 in postnatal survival and male reproduction. Proc Natl Acad Sci U S A. 2004 Mar 30; 101(13):4453-8. PMID: 15070739.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    338. Mollenhauer J, Helmke B, Medina D, Bergmann G, Gassler N, Müller H, Lyer S, Diedrichs L, Renner M, Wittig R, Blaich S, Hamann U, Madsen J, Holmskov U, Bikker F, Ligtenberg A, Carlén A, Olsson J, Otto HF, O'Malley B, Poustka A. Carcinogen inducibility in vivo and down-regulation of DMBT1 during breast carcinogenesis. Genes Chromosomes Cancer. 2004 Mar; 39(3):185-94. PMID: 14732920.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    339. Kuang SQ, Liao L, Zhang H, Lee AV, O'Malley BW, Xu J. AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice. Cancer Res. 2004 Mar 01; 64(5):1875-85. PMID: 14996752.
      Citations: 84     Fields:    Translation:AnimalsCells
    340. Auboeuf D, Dowhan DH, Kang YK, Larkin K, Lee JW, Berget SM, O'Malley BW. Differential recruitment of nuclear receptor coactivators may determine alternative RNA splice site choice in target genes. Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8):2270-4. PMID: 14982999.
      Citations: 44     Fields:    Translation:Cells
    341. Reddy DS, Castaneda DC, O'Malley BW, Rogawski MA. Anticonvulsant activity of progesterone and neurosteroids in progesterone receptor knockout mice. J Pharmacol Exp Ther. 2004 Jul; 310(1):230-9. PMID: 14982969.
      Citations: 60     Fields:    Translation:Animals
    342. Smith CL, O'Malley BW. Coregulator function: a key to understanding tissue specificity of selective receptor modulators. Endocr Rev. 2004 Feb; 25(1):45-71. PMID: 14769827.
      Citations: 241     Fields:    Translation:HumansAnimals
    343. Auboeuf D, Dowhan DH, Li X, Larkin K, Ko L, Berget SM, O'Malley BW. CoAA, a nuclear receptor coactivator protein at the interface of transcriptional coactivation and RNA splicing. Mol Cell Biol. 2004 Jan; 24(1):442-53. PMID: 14673176.
      Citations: 67     Fields:    Translation:HumansCells
    344. Lonard DM, Tsai SY, O'Malley BW. Selective estrogen receptor modulators 4-hydroxytamoxifen and raloxifene impact the stability and function of SRC-1 and SRC-3 coactivator proteins. Mol Cell Biol. 2004 Jan; 24(1):14-24. PMID: 14673139.
      Citations: 27     Fields:    Translation:HumansCells
    345. Nawaz Z, O'Malley BW. Urban renewal in the nucleus: is protein turnover by proteasomes absolutely required for nuclear receptor-regulated transcription? Mol Endocrinol. 2004 Mar; 18(3):493-9. PMID: 14673136.
      Citations: 38     Fields:    Translation:Cells
    346. Ismail PM, Amato P, Soyal SM, DeMayo FJ, Conneely OM, O'Malley BW, Lydon JP. Progesterone involvement in breast development and tumorigenesis--as revealed by progesterone receptor "knockout" and "knockin" mouse models. Steroids. 2003 Nov; 68(10-13):779-87. PMID: 14667968.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    347. Apostolakis EM, Lanz R, O'Malley BW. Pituitary adenylate cyclase-activating peptide: a pivotal modulator of steroid-induced reproductive behavior in female rodents. Mol Endocrinol. 2004 Jan; 18(1):173-83. PMID: 14593074.
      Citations: 15     Fields:    Translation:Animals
    348. O'Malley BW. Sequentiality and processivity of nuclear receptor coregulators in regulation of target gene expression. Nucl Recept Signal. 2003; 1:e010. PMID: 16604182.
      Citations: 6     Fields:    
    349. Mödder UI, Sanyal A, Kearns AE, Sibonga JD, Nishihara E, Xu J, O'Malley BW, Ritman EL, Riggs BL, Spelsberg TC, Khosla S. Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. Endocrinology. 2004 Feb; 145(2):913-21. PMID: 14563705.
      Citations: 34     Fields:    Translation:Animals
    350. Lanz RB, Chua SS, Barron N, Söder BM, DeMayo F, O'Malley BW. Steroid receptor RNA activator stimulates proliferation as well as apoptosis in vivo. Mol Cell Biol. 2003 Oct; 23(20):7163-76. PMID: 14517287.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    351. Kamiya Y, Zhang XY, Ying H, Kato Y, Willingham MC, Xu J, O'Malley BW, Cheng SY. Modulation by steroid receptor coactivator-1 of target-tissue responsiveness in resistance to thyroid hormone. Endocrinology. 2003 Sep; 144(9):4144-53. PMID: 12933689.
      Citations: 15     Fields:    Translation:Animals
    352. Lan ZJ, Gu P, Xu X, Jackson KJ, DeMayo FJ, O'Malley BW, Cooney AJ. GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility. EMBO J. 2003 Aug 15; 22(16):4070-81. PMID: 12912906.
      Citations: 27     Fields:    Translation:AnimalsCells
    353. Dasgupta S, Tripathi PK, Bhattacharya-Chatterjee M, O'Malley B, Chatterjee SK. Recombinant vaccinia virus expressing IL-2 generates effective anti-tumor responses in an orthotopic murine model of head and neck carcinoma. Mol Ther. 2003 Aug; 8(2):238-48. PMID: 12907146.
      Citations: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    354. Ghoumari AM, Ibanez C, El-Etr M, Leclerc P, Eychenne B, O'Malley BW, Baulieu EE, Schumacher M. Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum. J Neurochem. 2003 Aug; 86(4):848-59. PMID: 12887683.
      Citations: 65     Fields:    Translation:AnimalsCells
    355. Li X, O'Malley BW. Unfolding the action of progesterone receptors. J Biol Chem. 2003 Oct 10; 278(41):39261-4. PMID: 12893816.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    356. Monks DA, Xu J, O'Malley BW, Jordan CL. Steroid receptor coactivator-1 is not required for androgen-mediated sexual differentiation of spinal motoneurons. Neuroendocrinology. 2003 Jul; 78(1):45-51. PMID: 12869799.
      Citations: 8     Fields:    Translation:AnimalsCells
    357. Li X, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Progesterone and glucocorticoid receptors recruit distinct coactivator complexes and promote distinct patterns of local chromatin modification. Mol Cell Biol. 2003 Jun; 23(11):3763-73. PMID: 12748280.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    358. Sadow PM, Chassande O, Koo EK, Gauthier K, Samarut J, Xu J, O'Malley BW, Weiss RE. Regulation of expression of thyroid hormone receptor isoforms and coactivators in liver and heart by thyroid hormone. Mol Cell Endocrinol. 2003 May 30; 203(1-2):65-75. PMID: 12782404.
      Citations: 10     Fields:    Translation:Animals
    359. Rance J, Phillips C, Davies S, O'Malley B, Zaman Q, Price D. How much of a priority is treating erectile dysfunction? A study of patients' perceptions. Diabet Med. 2003 Mar; 20(3):205-9. PMID: 12675664.
      Citations:    Fields:    Translation:Humans
    360. Schneider JS, Stone MK, Wynne-Edwards KE, Horton TH, Lydon J, O'Malley B, Levine JE. Progesterone receptors mediate male aggression toward infants. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2951-6. PMID: 12601162.
      Citations: 32     Fields:    Translation:Animals
    361. Sadow PM, Koo E, Chassande O, Gauthier K, Samarut J, Xu J, O'Malley BW, Seo H, Murata Y, Weiss RE. Thyroid hormone receptor-specific interactions with steroid receptor coactivator-1 in the pituitary. Mol Endocrinol. 2003 May; 17(5):882-94. PMID: 12576486.
      Citations: 8     Fields:    Translation:AnimalsCells
    362. Cheskis BJ, McKenna NJ, Wong CW, Wong J, Komm B, Lyttle CR, O'Malley BW. Hierarchical affinities and a bipartite interaction model for estrogen receptor isoforms and full-length steroid receptor coactivator (SRC/p160) family members. J Biol Chem. 2003 Apr 11; 278(15):13271-7. PMID: 12540843.
      Citations: 7     Fields:    Translation:AnimalsCells
    363. Nishihara E, Yoshida-Komiya H, Chan CS, Liao L, Davis RL, O'Malley BW, Xu J. SRC-1 null mice exhibit moderate motor dysfunction and delayed development of cerebellar Purkinje cells. J Neurosci. 2003 Jan 01; 23(1):213-22. PMID: 12514218.
      Citations: 49     Fields:    Translation:AnimalsCells
    364. Picard F, Géhin M, Annicotte J, Rocchi S, Champy MF, O'Malley BW, Chambon P, Auwerx J. SRC-1 and TIF2 control energy balance between white and brown adipose tissues. Cell. 2002 Dec 27; 111(7):931-41. PMID: 12507421.
      Citations: 174     Fields:    Translation:AnimalsCells
    365. Liao L, Kuang SQ, Yuan Y, Gonzalez SM, O'Malley BW, Xu J. Molecular structure and biological function of the cancer-amplified nuclear receptor coactivator SRC-3/AIB1. J Steroid Biochem Mol Biol. 2002 Dec; 83(1-5):3-14. PMID: 12650696.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    366. Lanz RB, Razani B, Goldberg AD, O'Malley BW. Distinct RNA motifs are important for coactivation of steroid hormone receptors by steroid receptor RNA activator (SRA). Proc Natl Acad Sci U S A. 2002 Dec 10; 99(25):16081-6. PMID: 12444263.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    367. Picard F, Wanatabe M, Schoonjans K, Lydon J, O'Malley BW, Auwerx J. Progesterone receptor knockout mice have an improved glucose homeostasis secondary to beta -cell proliferation. Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15644-8. PMID: 12438645.
      Citations: 41     Fields:    Translation:AnimalsCells
    368. Ismail PM, Li J, DeMayo FJ, O'Malley BW, Lydon JP. A novel LacZ reporter mouse reveals complex regulation of the progesterone receptor promoter during mammary gland development. Mol Endocrinol. 2002 Nov; 16(11):2475-89. PMID: 12403837.
      Citations: 55     Fields:    Translation:AnimalsCells
    369. Auboeuf D, Hönig A, Berget SM, O'Malley BW. Coordinate regulation of transcription and splicing by steroid receptor coregulators. Science. 2002 Oct 11; 298(5592):416-9. PMID: 12376702.
      Citations: 120     Fields:    Translation:HumansAnimalsCells
    370. Sadow PM, Chassande O, Gauthier K, Samarut J, Xu J, O'Malley BW, Weiss RE. Specificity of thyroid hormone receptor subtype and steroid receptor coactivator-1 on thyroid hormone action. Am J Physiol Endocrinol Metab. 2003 Jan; 284(1):E36-46. PMID: 12388168.
      Citations: 10     Fields:    Translation:AnimalsCells
    371. Xu J, O'Malley BW. Molecular mechanisms and cellular biology of the steroid receptor coactivator (SRC) family in steroid receptor function. Rev Endocr Metab Disord. 2002 Sep; 3(3):185-92. PMID: 12215713.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    372. Hönig A, Auboeuf D, Parker MM, O'Malley BW, Berget SM. Regulation of alternative splicing by the ATP-dependent DEAD-box RNA helicase p72. Mol Cell Biol. 2002 Aug; 22(16):5698-707. PMID: 12138182.
      Citations: 50     Fields:    Translation:HumansCells
    373. McKenna NJ, O'Malley BW. Minireview: nuclear receptor coactivators--an update. Endocrinology. 2002 Jul; 143(7):2461-5. PMID: 12072374.
      Citations: 98     Fields:    Translation:HumansAnimals
    374. Apostolakis EM, Ramamurphy M, Zhou D, Oñate S, O'Malley BW. Acute disruption of select steroid receptor coactivators prevents reproductive behavior in rats and unmasks genetic adaptation in knockout mice. Mol Endocrinol. 2002 Jul; 16(7):1511-23. PMID: 12089347.
      Citations: 35     Fields:    Translation:AnimalsCells
    375. Cao T, Tsai SY, O'Malley BW, Wang XJ, Roop DR. The epidermis as a bioreactor: topically regulated cutaneous delivery into the circulation. Hum Gene Ther. 2002 Jun 10; 13(9):1075-80. PMID: 12067440.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    376. Liu Z, Auboeuf D, Wong J, Chen JD, Tsai SY, Tsai MJ, O'Malley BW. Coactivator/corepressor ratios modulate PR-mediated transcription by the selective receptor modulator RU486. Proc Natl Acad Sci U S A. 2002 Jun 11; 99(12):7940-4. PMID: 12048256.
      Citations: 34     Fields:    Translation:HumansCells
    377. Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol. 2002 May; 22(10):3549-61. PMID: 11971985.
      Citations: 108     Fields:    Translation:HumansAnimalsCells
    378. Sivaraman L, Gay J, Hilsenbeck SG, Shine HD, Conneely OM, Medina D, O'Malley BW. Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis. Breast Cancer Res Treat. 2002 May; 73(1):75-83. PMID: 12083633.
      Citations: 3     Fields:    Translation:AnimalsCells
    379. Takeuchi Y, Murata Y, Sadow P, Hayashi Y, Seo H, Xu J, O'Malley BW, Weiss RE, Refetoff S. Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo. Endocrinology. 2002 Apr; 143(4):1346-52. PMID: 11897691.
      Citations: 16     Fields:    Translation:Animals
    380. Weiss RE, Gehin M, Xu J, Sadow PM, O'Malley BW, Chambon P, Refetoff S. Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency. Endocrinology. 2002 Apr; 143(4):1554-7. PMID: 11897715.
      Citations: 8     Fields:    Translation:Animals
    381. McKenna NJ, O'Malley BW. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell. 2002 Feb 22; 108(4):465-74. PMID: 11909518.
      Citations: 433     Fields:    Translation:HumansAnimalsCells
    382. Cavarretta IT, Mukopadhyay R, Lonard DM, Cowsert LM, Bennett CF, O'Malley BW, Smith CL. Reduction of coactivator expression by antisense oligodeoxynucleotides inhibits ERalpha transcriptional activity and MCF-7 proliferation. Mol Endocrinol. 2002 Feb; 16(2):253-70. PMID: 11818499.
      Citations: 25     Fields:    Translation:HumansCells
    383. Markaverich B, Mani S, Alejandro MA, Mitchell A, Markaverich D, Brown T, Velez-Trippe C, Murchison C, O'Malley B, Faith R. A novel endocrine-disrupting agent in corn with mitogenic activity in human breast and prostatic cancer cells. Environ Health Perspect. 2002 Feb; 110(2):169-77. PMID: 11836146.
      Citations: 30     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    384. Finn FM, O'Malley BW. Klaus Hofmann, February 21, 1911 - December 25, 1995. Biogr Mem Natl Acad Sci. 2002; 81:116-34. PMID: 12661557.
      Citations:    
    385. Ye X, Schillinger K, Burcin MM, Tsai SY, O'Malley BW. Ligand-inducible transgene regulation for gene therapy. Methods Enzymol. 2002; 346:551-61. PMID: 11883090.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    386. Smith CL, DeVera DG, Lamb DJ, Nawaz Z, Jiang YH, Beaudet AL, O'Malley BW. Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction. Mol Cell Biol. 2002 Jan; 22(2):525-35. PMID: 11756548.
      Citations: 23     Fields:    Translation:Animals
    387. Conneely OM, Mulac-Jericevic B, DeMayo F, Lydon JP, O'Malley BW. Reproductive functions of progesterone receptors. Recent Prog Horm Res. 2002; 57:339-55. PMID: 12017551.
      Citations: 82     Fields:    Translation:HumansAnimals
    388. McKenna NJ, O'Malley BW. Nuclear receptors, coregulators, ligands, and selective receptor modulators: making sense of the patchwork quilt. Ann N Y Acad Sci. 2001 Dec; 949:3-5. PMID: 11795367.
      Citations: 34     Fields:    Translation:Humans
    389. Liu Z, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12426-31. PMID: 11606780.
      Citations: 39     Fields:    Translation:HumansCells
    390. Sivaraman L, Conneely OM, Medina D, O'Malley BW. p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12379-84. PMID: 11606748.
      Citations: 40     Fields:    Translation:Animals
    391. Sivaraman L, Hilsenbeck SG, Zhong L, Gay J, Conneely OM, Medina D, O'Malley BW. Early exposure of the rat mammary gland to estrogen and progesterone blocks co-localization of estrogen receptor expression and proliferation. J Endocrinol. 2001 Oct; 171(1):75-83. PMID: 11572792.
      Citations: 13     Fields:    Translation:Animals
    392. Karas RH, van Eickels M, Lydon JP, Roddy S, Kwoun M, Aronovitz M, Baur WE, Conneely O, O'Malley BW, Mendelsohn ME. A complex role for the progesterone receptor in the response to vascular injury. J Clin Invest. 2001 Aug; 108(4):611-8. PMID: 11518735.
      Citations: 7     Fields:    Translation:AnimalsCells
    393. Monitto CL, Berkowitz D, Lee KM, Pin S, Li D, Breslow M, O'Malley B, Schiller M. Differential gene expression in a murine model of cancer cachexia. Am J Physiol Endocrinol Metab. 2001 Aug; 281(2):E289-97. PMID: 11440905.
      Citations: 7     Fields:    Translation:AnimalsCells
    394. Stenoien DL, Nye AC, Mancini MG, Patel K, Dutertre M, O'Malley BW, Smith CL, Belmont AS, Mancini MA. Ligand-mediated assembly and real-time cellular dynamics of estrogen receptor alpha-coactivator complexes in living cells. Mol Cell Biol. 2001 Jul; 21(13):4404-12. PMID: 11390668.
      Citations: 51     Fields:    Translation:AnimalsCells
    395. Kurita T, Wang YZ, Donjacour AA, Zhao C, Lydon JP, O'Malley BW, Isaacs JT, Dahiya R, Cunha GR. Paracrine regulation of apoptosis by steroid hormones in the male and female reproductive system. Cell Death Differ. 2001 Feb; 8(2):192-200. PMID: 11313721.
      Citations: 48     Fields:    Translation:AnimalsCells
    396. Mani SK, Mitchell A, O'Malley BW. Progesterone receptor and dopamine receptors are required in Delta 9-tetrahydrocannabinol modulation of sexual receptivity in female rats. Proc Natl Acad Sci U S A. 2001 Jan 30; 98(3):1249-54. PMID: 11158625.
      Citations: 16     Fields:    Translation:Animals
    397. New MI, Nimkarn S, Brandon DD, Cunningham-Rundles S, Wilson RC, Newfield RS, Vandermeulen J, Barron N, Russo C, Loriaux DL, O'Malley B. Resistance to multiple steroids in two sisters. J Steroid Biochem Mol Biol. 2001 Jan-Mar; 76(1-5):161-6. PMID: 11384874.
      Citations: 2     Fields:    Translation:Humans
    398. Chung AC, Katz D, Pereira FA, Jackson KJ, DeMayo FJ, Cooney AJ, O'Malley BW. Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation. Mol Cell Biol. 2001 Jan; 21(2):663-77. PMID: 11134352.
      Citations: 36     Fields:    Translation:Animals
    399. Stenoien DL, Patel K, Mancini MG, Dutertre M, Smith CL, O'Malley BW, Mancini MA. FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nat Cell Biol. 2001 Jan; 3(1):15-23. PMID: 11146621.
      Citations: 113     Fields:    Translation:HumansCells
    400. Rowan BG, Garrison N, Weigel NL, O'Malley BW. 8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein. Mol Cell Biol. 2000 Dec; 20(23):8720-30. PMID: 11073973.
      Citations: 64     Fields:    Translation:AnimalsCells
    401. McKenna NJ, O'Malley BW. From ligand to response: generating diversity in nuclear receptor coregulator function. J Steroid Biochem Mol Biol. 2000 Nov 30; 74(5):351-6. PMID: 11162944.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    402. Robker RL, Russell DL, Yoshioka S, Sharma SC, Lydon JP, O'Malley BW, Espey LL, Richards JS. Ovulation: a multi-gene, multi-step process. Steroids. 2000 Oct-Nov; 65(10-11):559-70. PMID: 11108860.
      Citations: 26     Fields:    Translation:AnimalsCells
    403. Rowan BG, O'Malley BW. Progesterone receptor coactivators. Steroids. 2000 Oct-Nov; 65(10-11):545-9. PMID: 11108858.
      Citations: 12     Fields:    Translation:HumansAnimals
    404. Abruzzese RV, Godin D, Mehta V, Perrard JL, French M, Nelson W, Howell G, Coleman M, O'Malley BW, Nordstrom JL. Ligand-dependent regulation of vascular endothelial growth factor and erythropoietin expression by a plasmid-based autoinducible GeneSwitch system. Mol Ther. 2000 Sep; 2(3):276-87. PMID: 10985958.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    405. McKenna NJ, O'Malley BW. An issue of tissues: divining the split personalities of selective estrogen receptor modulators. Nat Med. 2000 Sep; 6(9):960-2. PMID: 10973303.
      Citations: 14     Fields:    Translation:HumansCells
    406. Sivaraman L, Nawaz Z, Medina D, Conneely OM, O'Malley BW. The dual function steroid receptor coactivator/ubiquitin protein-ligase integrator E6-AP is overexpressed in mouse mammary tumorigenesis. Breast Cancer Res Treat. 2000 Aug; 62(3):185-95. PMID: 11072783.
      Citations: 6     Fields:    Translation:Animals
    407. O'Malley B. Citation for the 2000 Edwin B. Astwood Award Lecture of The Endocrine Society to Dr. Jeffrey M. Rosen. Endocr Rev. 2000 Aug; 21(4):449. PMID: 10950163.
      Citations:    Fields:    
    408. Apostolakis EM, Garai J, Lohmann JE, Clark JH, O'Malley BW. Epidermal growth factor activates reproductive behavior independent of ovarian steroids in female rodents. Mol Endocrinol. 2000 Jul; 14(7):1086-98. PMID: 10894157.
      Citations: 17     Fields:    Translation:Animals
    409. Xu J, Liao L, Ning G, Yoshida-Komiya H, Deng C, O'Malley BW. The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development. Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6379-84. PMID: 10823921.
      Citations: 183     Fields:    Translation:Animals
    410. Lonard DM, Nawaz Z, Smith CL, O'Malley BW. The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation. Mol Cell. 2000 Jun; 5(6):939-48. PMID: 10911988.
      Citations: 183     Fields:    Translation:HumansCells
    411. Robker RL, Russell DL, Espey LL, Lydon JP, O'Malley BW, Richards JS. Progesterone-regulated genes in the ovulation process: ADAMTS-1 and cathepsin L proteases. Proc Natl Acad Sci U S A. 2000 Apr 25; 97(9):4689-94. PMID: 10781075.
      Citations: 109     Fields:    Translation:AnimalsCells
    412. Li J, O'Malley BW, Wong J. p300 requires its histone acetyltransferase activity and SRC-1 interaction domain to facilitate thyroid hormone receptor activation in chromatin. Mol Cell Biol. 2000 Mar; 20(6):2031-42. PMID: 10688650.
      Citations: 44     Fields:    Translation:AnimalsCells
    413. Rowan BG, Weigel NL, O'Malley BW. Phosphorylation of steroid receptor coactivator-1. Identification of the phosphorylation sites and phosphorylation through the mitogen-activated protein kinase pathway. J Biol Chem. 2000 Feb 11; 275(6):4475-83. PMID: 10660621.
      Citations: 59     Fields:    Translation:AnimalsCells
    414. Mani SK, Fienberg AA, O'Callaghan JP, Snyder GL, Allen PB, Dash PK, Moore AN, Mitchell AJ, Bibb J, Greengard P, O'Malley BW. Requirement for DARPP-32 in progesterone-facilitated sexual receptivity in female rats and mice. Science. 2000 Feb 11; 287(5455):1053-6. PMID: 10669419.
      Citations: 35     Fields:    Translation:AnimalsCells
    415. Conneely OM, Lydon JP, De Mayo F, O'Malley BW. Reproductive functions of the progesterone receptor. J Soc Gynecol Investig. 2000 Jan-Feb; 7(1 Suppl):S25-32. PMID: 10732326.
      Citations: 15     Fields:    Translation:HumansAnimals
    416. Wang Y, Tsai SY, O'Malley BW. An antiprogestin regulable gene switch for induction of gene expression in vivo. Adv Pharmacol. 2000; 47:343-55. PMID: 10582091.
      Citations: 1     Fields:    Translation:HumansAnimals
    417. Zhou D, Apostolakis EM, O'Malley BW. Distribution of D(5) dopamine receptor mRNA in rat ventromedial hypothalamic nucleus. Biochem Biophys Res Commun. 1999 Dec 20; 266(2):556-9. PMID: 10600540.
      Citations: 3     Fields:    Translation:Animals
    418. New MI, Nimkarn S, Brandon DD, Cunningham-Rundles S, Wilson RC, Newfield RS, Vandermeulen J, Barron N, Russo C, Loriaux DL, O'Malley B. Resistance to several steroids in two sisters. J Clin Endocrinol Metab. 1999 Dec; 84(12):4454-64. PMID: 10599702.
      Citations: 5     Fields:    Translation:Humans
    419. Puigserver P, Adelmant G, Wu Z, Fan M, Xu J, O'Malley B, Spiegelman BM. Activation of PPARgamma coactivator-1 through transcription factor docking. Science. 1999 Nov 12; 286(5443):1368-71. PMID: 10558993.
      Citations: 217     Fields:    Translation:AnimalsCells
    420. Tibbetts TA, DeMayo F, Rich S, Conneely OM, O'Malley BW. Progesterone receptors in the thymus are required for thymic involution during pregnancy and for normal fertility. Proc Natl Acad Sci U S A. 1999 Oct 12; 96(21):12021-6. PMID: 10518569.
      Citations: 42     Fields:    Translation:AnimalsCells
    421. Smith CL, O'Malley BW. Evolving concepts of selective estrogen receptor action: from basic science to clinical applications. Trends Endocrinol Metab. 1999 Oct; 10(8):299-300. PMID: 10481159.
      Citations: 2     Fields:    
    422. Lydon JP, Ge G, Kittrell FS, Medina D, O'Malley BW. Murine mammary gland carcinogenesis is critically dependent on progesterone receptor function. Cancer Res. 1999 Sep 01; 59(17):4276-84. PMID: 10485472.
      Citations: 63     Fields:    Translation:Animals
    423. Liu Z, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9485-90. PMID: 10449719.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    424. Chappell PE, Schneider JS, Kim P, Xu M, Lydon JP, O'Malley BW, Levine JE. Absence of gonadotropin surges and gonadotropin-releasing hormone self-priming in ovariectomized (OVX), estrogen (E2)-treated, progesterone receptor knockout (PRKO) mice. Endocrinology. 1999 Aug; 140(8):3653-8. PMID: 10433223.
      Citations: 47     Fields:    Translation:Animals
    425. Wang XJ, Liefer KM, Tsai S, O'Malley BW, Roop DR. Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis. Proc Natl Acad Sci U S A. 1999 Jul 20; 96(15):8483-8. PMID: 10411901.
      Citations: 32     Fields:    Translation:AnimalsCells
    426. Simon C, Hicks MJ, Nemechek AJ, Mehta R, O'Malley BW, Goepfert H, Flaitz CM, Boyd D. PD 098059, an inhibitor of ERK1 activation, attenuates the in vivo invasiveness of head and neck squamous cell carcinoma. Br J Cancer. 1999 Jul; 80(9):1412-9. PMID: 10424744.
      Citations: 9     Fields:    Translation:HumansAnimals
    427. Abruzzese RV, Godin D, Burcin M, Mehta V, French M, Li Y, O'Malley BW, Nordstrom JL. Ligand-dependent regulation of plasmid-based transgene expression in vivo. Hum Gene Ther. 1999 Jun 10; 10(9):1499-507. PMID: 10395375.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    428. McKenna NJ, Lanz RB, O'Malley BW. Nuclear receptor coregulators: cellular and molecular biology. Endocr Rev. 1999 Jun; 20(3):321-44. PMID: 10368774.
      Citations: 448     Fields:    Translation:HumansAnimalsCells
    429. Tibbetts TA, Conneely OM, O'Malley BW. Progesterone via its receptor antagonizes the pro-inflammatory activity of estrogen in the mouse uterus. Biol Reprod. 1999 May; 60(5):1158-65. PMID: 10208978.
      Citations: 51     Fields:    Translation:AnimalsCells
    430. Lanz RB, McKenna NJ, Onate SA, Albrecht U, Wong J, Tsai SY, Tsai MJ, O'Malley BW. A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 1999 Apr 02; 97(1):17-27. PMID: 10199399.
      Citations: 265     Fields:    Translation:HumansAnimalsCells
    431. Weiss RE, Xu J, Ning G, Pohlenz J, O'Malley BW, Refetoff S. Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone. EMBO J. 1999 Apr 01; 18(7):1900-4. PMID: 10202153.
      Citations: 68     Fields:    Translation:Animals
    432. McKenna NJ, Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions. J Steroid Biochem Mol Biol. 1999 Apr-Jun; 69(1-6):3-12. PMID: 10418975.
      Citations: 81     Fields:    Translation:HumansAnimals
    433. Nawaz Z, Lonard DM, Dennis AP, Smith CL, O'Malley BW. Proteasome-dependent degradation of the human estrogen receptor. Proc Natl Acad Sci U S A. 1999 Mar 02; 96(5):1858-62. PMID: 10051559.
      Citations: 161     Fields:    Translation:HumansAnimalsCells
    434. Nawaz Z, Lonard DM, Smith CL, Lev-Lehman E, Tsai SY, Tsai MJ, O'Malley BW. The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol Cell Biol. 1999 Feb; 19(2):1182-9. PMID: 9891052.
      Citations: 134     Fields:    Translation:HumansCells
    435. Vázquez F, Rodríguez-Manzaneque JC, Lydon JP, Edwards DP, O'Malley BW, Iruela-Arispe ML. Progesterone regulates proliferation of endothelial cells. J Biol Chem. 1999 Jan 22; 274(4):2185-92. PMID: 9890981.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    436. Burcin MM, Schiedner G, Kochanek S, Tsai SY, O'Malley BW. Adenovirus-mediated regulable target gene expression in vivo. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):355-60. PMID: 9892637.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    437. Wang Y, Tsai SY, O'Malley BW. Antiprogestin regulable gene switch for induction of gene expression in vivo. Methods Enzymol. 1999; 306:281-94. PMID: 10432460.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    438. Phelps SM, Lydon JP, O'malley BW, Crews D. Regulation of male sexual behavior by progesterone receptor, sexual experience, and androgen. Horm Behav. 1998 Dec; 34(3):294-302. PMID: 9878278.
      Citations: 16     Fields:    Translation:Animals
    439. Kurita T, Young P, Brody JR, Lydon JP, O'Malley BW, Cunha GR. Stromal progesterone receptors mediate the inhibitory effects of progesterone on estrogen-induced uterine epithelial cell deoxyribonucleic acid synthesis. Endocrinology. 1998 Nov; 139(11):4708-13. PMID: 9794483.
      Citations: 64     Fields:    Translation:AnimalsCells
    440. Tibbetts TA, Mendoza-Meneses M, O'Malley BW, Conneely OM. Mutual and intercompartmental regulation of estrogen receptor and progesterone receptor expression in the mouse uterus. Biol Reprod. 1998 Nov; 59(5):1143-52. PMID: 9780321.
      Citations: 45     Fields:    Translation:AnimalsCells
    441. McKenna NJ, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Distinct steady-state nuclear receptor coregulator complexes exist in vivo. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11697-702. PMID: 9751728.
      Citations: 48     Fields:    Translation:HumansCells
    442. Sivaraman L, Stephens LC, Markaverich BM, Clark JA, Krnacik S, Conneely OM, O'Malley BW, Medina D. Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats. Carcinogenesis. 1998 Sep; 19(9):1573-81. PMID: 9771927.
      Citations: 38     Fields:    Translation:Animals
    443. Jeng MH, Kao C, Sivaraman L, Krnacik S, Chung LW, Medina D, Conneely OM, O'Malley BW. Reconstitution of estrogen-dependent transcriptional activation of an adenoviral target gene in select regions of the rat mammary gland. Endocrinology. 1998 Jun; 139(6):2916-25. PMID: 9607802.
      Citations: 3     Fields:    Translation:AnimalsCells
    444. Onate SA, Boonyaratanakornkit V, Spencer TE, Tsai SY, Tsai MJ, Edwards DP, O'Malley BW. The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors. J Biol Chem. 1998 May 15; 273(20):12101-8. PMID: 9575154.
      Citations: 99     Fields:    Translation:HumansCells
    445. Brisken C, Park S, Vass T, Lydon JP, O'Malley BW, Weinberg RA. A paracrine role for the epithelial progesterone receptor in mammary gland development. Proc Natl Acad Sci U S A. 1998 Apr 28; 95(9):5076-81. PMID: 9560231.
      Citations: 160     Fields:    Translation:Animals
    446. Oligino T, Poliani PL, Wang Y, Tsai SY, O'Malley BW, Fink DJ, Glorioso JC. Drug inducible transgene expression in brain using a herpes simplex virus vector. Gene Ther. 1998 Apr; 5(4):491-6. PMID: 9614573.
      Citations: 4     Fields:    Translation:AnimalsCells
    447. Xu J, Qiu Y, DeMayo FJ, Tsai SY, Tsai MJ, O'Malley BW. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science. 1998 Mar 20; 279(5358):1922-5. PMID: 9506940.
      Citations: 187     Fields:    Translation:AnimalsCells
    448. Burcin MM, O'Malley BW, Tsai SY. A regulatory system for target gene expression. Front Biosci. 1998 Jan 01; 3:c1-7. PMID: 9478886.
      Citations: 15     Fields:    Translation:HumansAnimals
    449. Chappell PE, Lydon JP, Conneely OM, O'Malley BW, Levine JE. Endocrine defects in mice carrying a null mutation for the progesterone receptor gene. Endocrinology. 1997 Oct; 138(10):4147-52. PMID: 9322923.
      Citations: 42     Fields:    Translation:Animals
    450. Humphreys RC, Lydon JP, O'Malley BW, Rosen JM. Use of PRKO mice to study the role of progesterone in mammary gland development. J Mammary Gland Biol Neoplasia. 1997 Oct; 2(4):343-54. PMID: 10935022.
      Citations: 27     Fields:    Translation:Animals
    451. Spencer TE, Jenster G, Burcin MM, Allis CD, Zhou J, Mizzen CA, McKenna NJ, Onate SA, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature. 1997 Sep 11; 389(6647):194-8. PMID: 9296499.
      Citations: 303     Fields:    Translation:HumansAnimalsCells
    452. Said TK, Conneely OM, Medina D, O'Malley BW, Lydon JP. Progesterone, in addition to estrogen, induces cyclin D1 expression in the murine mammary epithelial cell, in vivo. Endocrinology. 1997 Sep; 138(9):3933-9. PMID: 9275084.
      Citations: 33     Fields:    Translation:AnimalsCells
    453. Chang KH, Chen Y, Chen TT, Chou WH, Chen PL, Ma YY, Yang-Feng TL, Leng X, Tsai MJ, O'Malley BW, Lee WH. A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9040-5. PMID: 9256431.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    454. Xiang M, Gan L, Li D, Chen ZY, Zhou L, O'Malley BW, Klein W, Nathans J. Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9445-50. PMID: 9256502.
      Citations: 91     Fields:    Translation:AnimalsCells
    455. Jenster G, Spencer TE, Burcin MM, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor induction of gene transcription: a two-step model. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):7879-84. PMID: 9223281.
      Citations: 47     Fields:    Translation:HumansCells
    456. Shibata H, Nawaz Z, Tsai SY, O'Malley BW, Tsai MJ. Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT). Mol Endocrinol. 1997 Jun; 11(6):714-24. PMID: 9171235.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    457. Smith CL, Nawaz Z, O'Malley BW. Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen. Mol Endocrinol. 1997 Jun; 11(6):657-66. PMID: 9171229.
      Citations: 125     Fields:    Translation:HumansCells
    458. Mani SK, Blaustein JD, O'Malley BW. Progesterone receptor function from a behavioral perspective. Horm Behav. 1997 Jun; 31(3):244-55. PMID: 9213138.
      Citations: 33     Fields:    Translation:Animals
    459. Humphreys RC, Lydon J, O'Malley BW, Rosen JM. Mammary gland development is mediated by both stromal and epithelial progesterone receptors. Mol Endocrinol. 1997 Jun; 11(6):801-11. PMID: 9171243.
      Citations: 50     Fields:    Translation:AnimalsCells
    460. Wang Y, Xu J, Pierson T, O'Malley BW, Tsai SY. Positive and negative regulation of gene expression in eukaryotic cells with an inducible transcriptional regulator. Gene Ther. 1997 May; 4(5):432-41. PMID: 9274720.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    461. Bai W, Rowan BG, Allgood VE, O'Malley BW, Weigel NL. Differential phosphorylation of chicken progesterone receptor in hormone-dependent and ligand-independent activation. J Biol Chem. 1997 Apr 18; 272(16):10457-63. PMID: 9099688.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    462. Gangolli EA, Conneely OM, O'Malley BW. Neurotransmitters activate the human estrogen receptor in a neuroblastoma cell line. J Steroid Biochem Mol Biol. 1997 Apr; 61(1-2):1-9. PMID: 9328204.
      Citations: 5     Fields:    Translation:HumansCells
    463. Wang Y, DeMayo FJ, Tsai SY, O'Malley BW. Ligand-inducible and liver-specific target gene expression in transgenic mice. Nat Biotechnol. 1997 Mar; 15(3):239-43. PMID: 9062922.
      Citations: 46     Fields:    Translation:AnimalsCells
    464. Allgood VE, Zhang Y, O'Malley BW, Weigel NL. Analysis of chicken progesterone receptor function and phosphorylation using an adenovirus-mediated procedure for high-efficiency DNA transfer. Biochemistry. 1997 Jan 07; 36(1):224-32. PMID: 8993337.
      Citations: 12     Fields:    Translation:AnimalsCells
    465. Shibata H, Spencer TE, Oñate SA, Jenster G, Tsai SY, Tsai MJ, O'Malley BW. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Prog Horm Res. 1997; 52:141-64; discussion 164-5. PMID: 9238851.
      Citations: 95     Fields:    Translation:HumansAnimalsCells
    466. Wang Y, O'Malley BW, Tsai SY. Inducible system designed for future gene therapy. Methods Mol Biol. 1997; 63:401-13. PMID: 9113665.
      Citations: 1     Fields:    Translation:AnimalsCells
    467. Mani SK, Allen JM, Lydon JP, Mulac-Jericevic B, Blaustein JD, DeMayo FJ, Conneely O, O'Malley BW. Dopamine requires the unoccupied progesterone receptor to induce sexual behavior in mice. Mol Endocrinol. 1996 Dec; 10(12):1728-37. PMID: 8961281.
      Citations: 44     Fields:    Translation:AnimalsCells
    468. Apostolakis EM, Garai J, Clark JH, O'Malley BW. In vivo regulation of central nervous system progesterone receptors: cocaine induces steroid-dependent behavior through dopamine transporter modulation of D5 receptors in rats. Mol Endocrinol. 1996 Dec; 10(12):1595-604. PMID: 8961269.
      Citations: 6     Fields:    Translation:AnimalsCells
    469. Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12195-9. PMID: 8901556.
      Citations: 17     Fields:    Translation:HumansCells
    470. McInerney EM, Tsai MJ, O'Malley BW, Katzenellenbogen BS. Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator. Proc Natl Acad Sci U S A. 1996 Sep 17; 93(19):10069-73. PMID: 8816752.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    471. Smith CL, Oñate SA, Tsai MJ, O'Malley BW. CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription. Proc Natl Acad Sci U S A. 1996 Aug 20; 93(17):8884-8. PMID: 8799122.
      Citations: 87     Fields:    Translation:HumansCells
    472. Apostolakis EM, Garai J, Fox C, Smith CL, Watson SJ, Clark JH, O'Malley BW. Dopaminergic regulation of progesterone receptors: brain D5 dopamine receptors mediate induction of lordosis by D1-like agonists in rats. J Neurosci. 1996 Aug 15; 16(16):4823-34. PMID: 8756415.
      Citations: 13     Fields:    Translation:AnimalsCells