Loading...
Header Logo
Keywords
Last Name
Institution

B V Venkatar Prasad

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Biochemistry & Molecular Biology
DivisionBiochemistry & Molecular Biology
vCardDownload vCard
    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular Virology & Microbiology
    DivisionMolecular Virology & Microbiology


    Collapse ORNG Applications 
    Collapse Faculty Mentor
    Collapse Aliases
    Collapse Verify Publications

    Collapse Biography 
    Collapse awards and honors
    2015• Elected Fellow of American Academy of Microbiology
    2013 • NIH MERIT Award
    2013 • Ruth Mclean Bowman Bowers Excellence in Research Award
    2010• Ruth Mclean Bowman Bowers Excellence in Research Award
    2004 - 2005• Indo-US Professorship of American Society of Microbiology
    2003 • NIH MERIT Award
    1983• Indian National Science Academy Young Scientist Award

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Stojanoski V, Sankaran B, Prasad BV, Poirel L, Nordmann P, Palzkill T. Structure of the catalytic domain of the colistin resistance enzyme MCR-1. BMC Biol. 2016 Sep 21; 14(1):81. PMID: 27655155.
      View in: PubMed
    2. Shanker S, Czakó R, Sapparapu G, Alvarado G, Viskovska M, Sankaran B, Atmar RL, Crowe JE, Estes MK, Prasad BV. Structural basis for norovirus neutralization by an HBGA blocking human IgA antibody. Proc Natl Acad Sci U S A. 2016 10 04; 113(40):E5830-E5837. PMID: 27647885.
      View in: PubMed
    3. Hesse S, Neill FH, Estes MK, Shanker S, Prasad BV, Ferreira J, Atmar RL. Correction for Hesse et al., Serological Responses to a Norovirus Nonstructural Fusion Protein after Vaccination and Infection. Clin Vaccine Immunol. 2016 08; 23(8):735. PMID: 27495982.
      View in: PubMed
    4. Sapparapu G, Czakó R, Alvarado G, Shanker S, Prasad BV, Atmar RL, Estes MK, Crowe JE. Frequent Use of the IgA Isotype in Human B Cells Encoding Potent Norovirus-Specific Monoclonal Antibodies That Block HBGA Binding. PLoS Pathog. 2016 06; 12(6):e1005719. PMID: 27355511.
      View in: PubMed
    5. Park GW, Collins N, Barclay L, Hu L, Prasad BV, Lopman BA, Vinjé J. Strain-Specific Virolysis Patterns of Human Noroviruses in Response to Alcohols. PLoS One. 2016; 11(6):e0157787. PMID: 27337036.
      View in: PubMed
    6. Prasad BV, Shanker S, Muhaxhiri Z, Deng L, Choi JM, Estes MK, Song Y, Palzkill T, Atmar RL. Antiviral targets of human noroviruses. Curr Opin Virol. 2016 06; 18:117-25. PMID: 27318434.
      View in: PubMed
    7. Stojanoski V, Adamski CJ, Hu L, Mehta SC, Sankaran B, Zwart P, Prasad BV, Palzkill T. Removal of the Side Chain at the Active-Site Serine by a Glycine Substitution Increases the Stability of a Wide Range of Serine ß-Lactamases by Relieving Steric Strain. Biochemistry. 2016 05 03; 55(17):2479-90. PMID: 27073009.
      View in: PubMed
    8. Hesse S, Neill FH, Estes MK, Shanker S, Prasad BV, Ferreira J, Atmar RL. Serological Responses to a Norovirus Nonstructural Fusion Protein after Vaccination and Infection. Clin Vaccine Immunol. 2016 02; 23(2):181-3. PMID: 26656120.
      View in: PubMed
    9. Ogden KM, Prasad BV. Quelling an innate response to dsRNA. Oncotarget. 2015 Oct 06; 6(30):28535-6. PMID: 26356565.
      View in: PubMed
    10. Hu L, Ramani S, Czako R, Sankaran B, Yu Y, Smith DF, Cummings RD, Estes MK, Venkataram Prasad BV. Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus. Nat Commun. 2015 Sep 30; 6:8346. PMID: 26420502.
      View in: PubMed
    11. Ogden KM, Hu L, Jha BK, Sankaran B, Weiss SR, Silverman RH, Patton JT, Prasad BV. Structural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist. J Virol. 2015 Jul; 89(13):6633-45. PMID: 25878106.
      View in: PubMed
    12. Chaudhry AS, Prasad B, Shirasaka Y, Fohner A, Finkelstein D, Fan Y, Wang S, Wu G, Aklillu E, Sim SC, Thummel KE, Schuetz EG. The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles. Drug Metab Dispos. 2015 Aug; 43(8):1226-35. PMID: 26021325.
      View in: PubMed
    13. Stojanoski V, Chow DC, Fryszczyn B, Hu L, Nordmann P, Poirel L, Sankaran B, Prasad BV, Palzkill T. Structural Basis for Different Substrate Profiles of Two Closely Related Class D ß-Lactamases and Their Inhibition by Halogens. Biochemistry. 2015 Jun 02; 54(21):3370-80. PMID: 25938261.
      View in: PubMed
    14. Stojanoski V, Chow DC, Hu L, Sankaran B, Gilbert HF, Prasad BV, Palzkill T. A triple mutant in the O-loop of TEM-1 ß-lactamase changes the substrate profile via a large conformational change and an altered general base for catalysis. J Biol Chem. 2015 Apr 17; 290(16):10382-94. PMID: 25713062.
      View in: PubMed
    15. Adamski CJ, Cardenas AM, Brown NG, Horton LB, Sankaran B, Prasad BV, Gilbert HF, Palzkill T. Molecular basis for the catalytic specificity of the CTX-M extended-spectrum ß-lactamases. Biochemistry. 2015 Jan 20; 54(2):447-57. PMID: 25489790.
      View in: PubMed
    16. Sastri NP, Viskovska M, Hyser JM, Tanner MR, Horton LB, Sankaran B, Prasad BV, Estes MK. Structural plasticity of the coiled-coil domain of rotavirus NSP4. J Virol. 2014 Dec; 88(23):13602-12. PMID: 25231315.
      View in: PubMed
    17. Viskovska M, Anish R, Hu L, Chow DC, Hurwitz AM, Brown NG, Palzkill T, Estes MK, Prasad BV. Probing the sites of interactions of rotaviral proteins involved in replication. J Virol. 2014 Nov; 88(21):12866-81. PMID: 25165107.
      View in: PubMed
    18. Venkataram Prasad BV, Air GM. Editorial overview: virus-glycan interactions and pathogenesis. Curr Opin Virol. 2014 Aug; 7:v-vi. PMID: 25128970.
      View in: PubMed
    19. Venkataram Prasad BV, Shanker S, Hu L, Choi JM, Crawford SE, Ramani S, Czako R, Atmar RL, Estes MK. Structural basis of glycan interaction in gastroenteric viral pathogens. Curr Opin Virol. 2014 Aug; 7:119-27. PMID: 25073118.
      View in: PubMed
    20. Ashline DJ, Yu Y, Lasanajak Y, Song X, Hu L, Ramani S, Prasad V, Estes MK, Cummings RD, Smith DF, Reinhold VN. Structural characterization by multistage mass spectrometry (MSn) of human milk glycans recognized by human rotaviruses. Mol Cell Proteomics. 2014 Nov; 13(11):2961-74. PMID: 25048706.
      View in: PubMed
    21. Yu Y, Lasanajak Y, Song X, Hu L, Ramani S, Mickum ML, Ashline DJ, Prasad BV, Estes MK, Reinhold VN, Cummings RD, Smith DF. Human milk contains novel glycans that are potential decoy receptors for neonatal rotaviruses. Mol Cell Proteomics. 2014 Nov; 13(11):2944-60. PMID: 25048705.
      View in: PubMed
    22. Qu L, Vongpunsawad S, Atmar RL, Prasad BV, Estes MK. Development of a Gaussia luciferase-based human norovirus protease reporter system: cell type-specific profile of Norwalk virus protease precursors and evaluation of inhibitors. J Virol. 2014 Sep; 88(18):10312-26. PMID: 25008934.
      View in: PubMed
    23. Shanker S, Czako R, Sankaran B, Atmar RL, Estes MK, Prasad BV. Structural analysis of determinants of histo-blood group antigen binding specificity in genogroup I noroviruses. J Virol. 2014 Jun; 88(11):6168-80. PMID: 24648450.
      View in: PubMed
    24. Carrillo B, Choi JM, Bornholdt ZA, Sankaran B, Rice AP, Prasad BV. The influenza A virus protein NS1 displays structural polymorphism. J Virol. 2014 Apr; 88(8):4113-22. PMID: 24478439.
      View in: PubMed
    25. Criglar JM, Hu L, Crawford SE, Hyser JM, Broughman JR, Prasad BV, Estes MK. A novel form of rotavirus NSP2 and phosphorylation-dependent NSP2-NSP5 interactions are associated with viroplasm assembly. J Virol. 2014 Jan; 88(2):786-98. PMID: 24198401.
      View in: PubMed
    26. Deng L, Muhaxhiri Z, Estes MK, Palzkill T, Prasad BV, Song Y. Synthesis, Activity and Structure-Activity Relationship of Noroviral Protease Inhibitors. Medchemcomm. 2013 Oct; 4(10). PMID: 24244836.
      View in: PubMed
    27. Rahman GM, Shanker S, Lewin NE, Kedei N, Hill CS, Prasad BV, Blumberg PM, Das J. Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase C? (PKC?). Biochem J. 2013 Jul 1; 453(1):153. PMID: 23763314.
      View in: PubMed
    28. Zheng B, Yao Y, Liu Z, Deng L, Anglin JL, Jiang H, Prasad BV, Song Y. Crystallographic Investigation and Selective Inhibition of Mutant Isocitrate Dehydrogenase. ACS Med Chem Lett. 2013 Jun 13; 4(6):542-546. PMID: 23795241.
      View in: PubMed
    29. Ramani S, Cortes-Penfield NW, Hu L, Crawford SE, Czako R, Smith DF, Kang G, Ramig RF, Le Pendu J, Prasad BV, Estes MK. The VP8* domain of neonatal rotavirus strain G10P[11] binds to type II precursor glycans. J Virol. 2013 Jul; 87(13):7255-64. PMID: 23616650.
      View in: PubMed
    30. Rahman GM, Shanker S, Lewin NE, Kedei N, Hill CS, Prasad BV, Blumberg PM, Das J. Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase C? (PKC?). Biochem J. 2013 Apr 01; 451(1):33-44. PMID: 23289588.
      View in: PubMed
    31. Vongpunsawad S, Venkataram Prasad BV, Estes MK. Norwalk Virus Minor Capsid Protein VP2 Associates within the VP1 Shell Domain. J Virol. 2013 May; 87(9):4818-25. PMID: 23408637.
      View in: PubMed
    32. Muhaxhiri Z, Deng L, Shanker S, Sankaran B, Estes MK, Palzkill T, Song Y, Prasad BV. Structural basis of substrate specificity and protease inhibition in Norwalk virus. J Virol. 2013 Apr; 87(8):4281-92. PMID: 23365454.
      View in: PubMed
    33. Ajami NJ, Barry MA, Carrillo B, Muhaxhiri Z, Neill FH, Prasad BV, Opekun AR, Gilger MA, Graham DY, Atmar RL, Estes MK. Antibody responses to norovirus genogroup GI.1 and GII.4 proteases in volunteers administered Norwalk virus. Clin Vaccine Immunol. 2012 Dec; 19(12):1980-3. PMID: 23035177.
      View in: PubMed
    34. Horton LB, Shanker S, Mikulski R, Brown NG, Phillips KJ, Lykissa E, Venkataram Prasad BV, Palzkill T. Mutagenesis of zinc ligand residue Cys221 reveals plasticity in the IMP-1 metallo-ß-lactamase active site. Antimicrob Agents Chemother. 2012 Nov; 56(11):5667-77. PMID: 22908171.
      View in: PubMed
    35. Hu L, Chow DC, Patton JT, Palzkill T, Estes MK, Prasad BV. Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity. J Virol. 2012 Oct; 86(19):10547-57. PMID: 22811529.
      View in: PubMed
    36. Hu L, Crawford SE, Hyser JM, Estes MK, Prasad BV. Rotavirus non-structural proteins: structure and function. Curr Opin Virol. 2012 Aug; 2(4):380-8. PMID: 22789743.
      View in: PubMed
    37. Hu L, Crawford SE, Czako R, Cortes-Penfield NW, Smith DF, Le Pendu J, Estes MK, Prasad BV. Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen. Nature. 2012 Apr 15; 485(7397):256-9. PMID: 22504179.
      View in: PubMed
    38. Prasad BV, Schmid MF. Principles of virus structural organization. Adv Exp Med Biol. 2012; 726:17-47. PMID: 22297509.
      View in: PubMed
    39. Baclayon M, Shoemaker GK, Uetrecht C, Crawford SE, Estes MK, Prasad BV, Heck AJ, Wuite GJ, Roos WH. Prestress strengthens the shell of Norwalk virus nanoparticles. Nano Lett. 2011 Nov 09; 11(11):4865-9. PMID: 21967663.
      View in: PubMed
    40. Yao Y, Chen P, Diao J, Cheng G, Deng L, Anglin JL, Prasad BV, Song Y. Selective inhibitors of histone methyltransferase DOT1L: design, synthesis, and crystallographic studies. J Am Chem Soc. 2011 Oct 26; 133(42):16746-9. PMID: 21936531.
      View in: PubMed
    41. Brown NG, Chow DC, Sankaran B, Zwart P, Prasad BV, Palzkill T. Analysis of the binding forces driving the tight interactions between beta-lactamase inhibitory protein-II (BLIP-II) and class A beta-lactamases. J Biol Chem. 2011 Sep 16; 286(37):32723-35. PMID: 21775426.
      View in: PubMed
    42. Shanker S, Choi JM, Sankaran B, Atmar RL, Estes MK, Prasad BV. Structural analysis of histo-blood group antigen binding specificity in a norovirus GII.4 epidemic variant: implications for epochal evolution. J Virol. 2011 Sep; 85(17):8635-45. PMID: 21715503.
      View in: PubMed
    43. Deng L, Diao J, Chen P, Pujari V, Yao Y, Cheng G, Crick DC, Prasad BV, Song Y. Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies. J Med Chem. 2011 Jul 14; 54(13):4721-34. PMID: 21561155.
      View in: PubMed
    44. Hu L, Crawford SE, Estes MK, Prasad BV. Rotavirus structure and functional implications. In “Viruses Responsible for Emerging Diseases in South-east Asia”. Eds: T.H. Nguyen Tran Hien, G. Baldacci, A. Haenni. Publishers: Science and Technology, Hanoi, Vietnam. 2011; pp 199-224.
    45. Shoemaker GK, van Duijn E, Crawford SE, Uetrecht C, Baclayon M, Roos WH, Wuite GJ, Estes MK, Prasad BV, Heck AJ. Norwalk virus assembly and stability monitored by mass spectrometry. Mol Cell Proteomics. 2010 Aug; 9(8):1742-51. PMID: 20418222.
      View in: PubMed
    46. Ossiboff RJ, Zhou Y, Lightfoot PJ, Prasad BV, Parker JS. Conformational changes in the capsid of a calicivirus upon interaction with its functional receptor. J Virol. 2010 Jun; 84(11):5550-64. PMID: 20357100.
      View in: PubMed
    47. Baker M, Prasad BV. Rotavirus cell entry. Curr Top Microbiol Immunol. 2010; 343:121-48. PMID: 20397068.
      View in: PubMed
    48. Bornholdt Z, Carrillo B, Prasad BV. . Structural insights into the function of influenza NS1. In "Influenza: Molecular Virology" Chapter 2 (Eds. Wang, Q., and Tao, Y.J) Horizon Scientific Press, Norfolk, UK. 2010; 15-28.
    49. Brown NG, Shanker S, Prasad BV, Palzkill T. Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis. J Biol Chem. 2009 Nov 27; 284(48):33703-12. PMID: 19812041.
      View in: PubMed
    50. Li Z, Baker ML, Jiang W, Estes MK, Prasad BV. Rotavirus architecture at subnanometer resolution. J Virol. 2009 Feb; 83(4):1754-66. PMID: 19036817.
      View in: PubMed
    51. Bornholdt ZA, Prasad BV. X-ray structure of NS1 from a highly pathogenic H5N1 influenza virus. Nature. 2008 Dec 18; 456(7224):985-8. PMID: 18987632.
      View in: PubMed
    52. Choi JM, Hutson AM, Estes MK, Prasad BV. Atomic resolution structural characterization of recognition of histo-blood group antigens by Norwalk virus. Proc Natl Acad Sci U S A. 2008 Jul 08; 105(27):9175-80. PMID: 18599458.
      View in: PubMed
    53. Kallewaard NL, McKinney BA, Gu Y, Chen A, Prasad BV, Crowe JE. Functional maturation of the human antibody response to rotavirus. J Immunol. 2008 Mar 15; 180(6):3980-9. PMID: 18322207.
      View in: PubMed
    54. Taraporewala Z, Kumar M, Prasad BV, Patton J. . Structure function of rotavirus NSP2 octamer, an essential component of the viroplasm. In "Structure and Molecular Biology of Segmented Double-Stranded RNA Viruses" (Ed. J. Patton). Horizon Scientific Press. 2008; pp 273-290.
    55. Jiang X, Crawford SE, Estes MK, Prasad BV. Rotavirus Structure. In "Structure and Molecular Biology of Segmented Double-Stranded RNA Viruses" (Ed. J. Patton). Horizon Scientific Press. 2008; pp45-60.
    56. Chung SH, Weiss RS, Frese KK, Prasad BV, Javier RT. Functionally distinct monomers and trimers produced by a viral oncoprotein. Oncogene. 2008 Feb 28; 27(10):1412-20. PMID: 17828302.
      View in: PubMed
    57. Kumar M, Jayaram H, Vasquez-Del Carpio R, Jiang X, Taraporewala ZF, Jacobson RH, Patton JT, Prasad BV. Crystallographic and biochemical analysis of rotavirus NSP2 with nucleotides reveals a nucleoside diphosphate kinase-like activity. J Virol. 2007 Nov; 81(22):12272-84. PMID: 17804496.
      View in: PubMed
    58. Chung SH, Frese KK, Weiss RS, Prasad BV, Javier RT. A new crucial protein interaction element that targets the adenovirus E4-ORF1 oncoprotein to membrane vesicles. J Virol. 2007 May; 81(9):4787-97. PMID: 17314165.
      View in: PubMed
    59. Estes MK, Prasad BV, Atmar RL. Noroviruses everywhere: has something changed? Curr Opin Infect Dis. 2006 Oct; 19(5):467-74. PMID: 16940871.
      View in: PubMed
    60. Jiang X, Jayaram H, Kumar M, Ludtke SJ, Estes MK, Prasad BV. Cryoelectron microscopy structures of rotavirus NSP2-NSP5 and NSP2-RNA complexes: implications for genome replication. J Virol. 2006 Nov; 80(21):10829-35. PMID: 16928740.
      View in: PubMed
    61. Taraporewala ZF, Jiang X, Vasquez-Del Carpio R, Jayaram H, Prasad BV, Patton JT. Structure-function analysis of rotavirus NSP2 octamer by using a novel complementation system. J Virol. 2006 Aug; 80(16):7984-94. PMID: 16873255.
      View in: PubMed
    62. Jayaram H, Fan H, Bowman BR, Ooi A, Jayaram J, Collisson EW, Lescar J, Prasad BV. X-ray structures of the N- and C-terminal domains of a coronavirus nucleocapsid protein: implications for nucleocapsid formation. J Virol. 2006 Jul; 80(13):6612-20. PMID: 16775348.
      View in: PubMed
    63. Bornholdt ZA, Prasad BV. X-ray structure of influenza virus NS1 effector domain. Nat Struct Mol Biol. 2006 Jun; 13(6):559-60. PMID: 16715094.
      View in: PubMed
    64. Chen R, Neill JD, Estes MK, Prasad BV. X-ray structure of a native calicivirus: structural insights into antigenic diversity and host specificity. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8048-53. PMID: 16702551.
      View in: PubMed
    65. Zeitler CE, Estes MK, Venkataram Prasad BV. X-ray crystallographic structure of the Norwalk virus protease at 1.5-A resolution. J Virol. 2006 May; 80(10):5050-8. PMID: 16641296.
      View in: PubMed
    66. Reddy DA, Prasad BV, Mitra CK. Comparative analysis of core promoter region: information content from mono and dinucleotide substitution matrices. Comput Biol Chem. 2006 Feb; 30(1):58-62. PMID: 16321573.
      View in: PubMed
    67. Monnier N, Higo-Moriguchi K, Sun ZY, Prasad BV, Taniguchi K, Dormitzer PR. High-resolution molecular and antigen structure of the VP8* core of a sialic acid-independent human rotavirus strain. J Virol. 2006 Feb; 80(3):1513-23. PMID: 16415027.
      View in: PubMed
    68. Pesavento JB, Crawford SE, Estes MK, Prasad BV. Rotavirus proteins: structure and assembly. Curr Top Microbiol Immunol. 2006; 309:189-219. PMID: 16913048.
      View in: PubMed
    69. Clark KM, Wetzel JD, Gu Y, Ebert DH, McAbee SA, Stoneman EK, Baer GS, Zhu Y, Wilson GJ, Prasad BV, Dermody TS. Reovirus variants selected for resistance to ammonium chloride have mutations in viral outer-capsid protein sigma3. J Virol. 2006 Jan; 80(2):671-81. PMID: 16378970.
      View in: PubMed
    70. Pesavento JB, Crawford SE, Roberts E, Estes MK, Prasad BV. pH-induced conformational change of the rotavirus VP4 spike: implications for cell entry and antibody neutralization. J Virol. 2005 Jul; 79(13):8572-80. PMID: 15956598.
      View in: PubMed
    71. Chakravarty S, Hutson AM, Estes MK, Prasad BV. Evolutionary trace residues in noroviruses: importance in receptor binding, antigenicity, virion assembly, and strain diversity. J Virol. 2005 Jan; 79(1):554-68. PMID: 15596848.
      View in: PubMed
    72. Dormitzer PR, Nason EB, Prasad BV, Harrison SC. Structural rearrangements in the membrane penetration protein of a non-enveloped virus. Nature. 2004 Aug 26; 430(7003):1053-8. PMID: 15329727.
      View in: PubMed
    73. Nason EL, Rothagel R, Mukherjee SK, Kar AK, Forzan M, Prasad BV, Roy P. Interactions between the inner and outer capsids of bluetongue virus. J Virol. 2004 Aug; 78(15):8059-67. PMID: 15254177.
      View in: PubMed
    74. Chen R, Neill JD, Noel JS, Hutson AM, Glass RI, Estes MK, Prasad BV. Inter- and intragenus structural variations in caliciviruses and their functional implications. J Virol. 2004 Jun; 78(12):6469-79. PMID: 15163740.
      View in: PubMed
    75. Jayaram H, Estes MK, Prasad BV. Emerging themes in rotavirus cell entry, genome organization, transcription and replication. Virus Res. 2004 Apr; 101(1):67-81. PMID: 15010218.
      View in: PubMed
    76. Crowther RA, Prasad BV. Macromolecular assemblages - putting the pieces together. Curr Opin Struct Biol. 2004 Apr; 14(2):117-20. PMID: 15093824.
      View in: PubMed
    77. Carpio RV, González-Nilo FD, Jayaram H, Spencer E, Prasad BV, Patton JT, Taraporewala ZF. Role of the histidine triad-like motif in nucleotide hydrolysis by the rotavirus RNA-packaging protein NSP2. J Biol Chem. 2004 Mar 12; 279(11):10624-33. PMID: 14699117.
      View in: PubMed
    78. Pesavento JB, Billingsley AM, Roberts EJ, Ramig RF, Prasad BV. Structures of rotavirus reassortants demonstrate correlation of altered conformation of the VP4 spike and expression of unexpected VP4-associated phenotypes. J Virol. 2003 Mar; 77(5):3291-6. PMID: 12584352.
      View in: PubMed
    79. Chen R, Neill JD, Prasad BV. Crystallization and preliminary crystallographic analysis of San Miguel sea lion virus: an animal calicivirus. J Struct Biol. 2003 Feb; 141(2):143-8. PMID: 12615540.
      View in: PubMed
    80. Prasad BV, Prevelige PE. Viral genome organization. Adv Protein Chem. 2003; 64:219-58. PMID: 13677049.
      View in: PubMed
    81. Chen R, Neill JD, Prasad BV. Crystallization and preliminary crystallographic analysis of San Miguel sea lion virus: An animal calicivirus. J. Struct. Biol. 2003; 141(2):143-148.
    82. Pesavento JB, Estes MK, Prasad BV. Structural organization of the genome in rotavirus. In "Viral Gastroenteritis: Perspectives in Medical Virology". (Eds: J. Gray and U.Desselberger), Elsevier. 2003; pp455-465.
    83. Bertolotti-Ciarlet A, Chen R, Estes MK, Prasad BV. Structure of Norwalk virus: the prototype human calicivirus. In "Viral Gastroenteritis: Perspectives in Medical Virology" (Eds: J. Gray and U.Desselberger). Elsevier. 2003; pp115-127,.
    84. Wilson GJ, Nason EL, Hardy CS, Ebert DH, Wetzel JD, Venkataram Prasad BV, Dermody TS. A single mutation in the carboxy terminus of reovirus outer-capsid protein sigma 3 confers enhanced kinetics of sigma 3 proteolysis, resistance to inhibitors of viral disassembly, and alterations in sigma 3 structure. J Virol. 2002 Oct; 76(19):9832-43. PMID: 12208961.
      View in: PubMed
    85. Jayaram H, Taraporewala Z, Patton JT, Prasad BV. Rotavirus protein involved in genome replication and packaging exhibits a HIT-like fold. Nature. 2002 May 16; 417(6886):311-5. PMID: 12015608.
      View in: PubMed
    86. Feng N, Lawton JA, Gilbert J, Kuklin N, Vo P, Prasad BV, Greenberg HB. Inhibition of rotavirus replication by a non-neutralizing, rotavirus VP6-specific IgA mAb. J Clin Invest. 2002 May; 109(9):1203-13. PMID: 11994409.
      View in: PubMed
    87. Bertolotti-Ciarlet A, White LJ, Chen R, Prasad BV, Estes MK. Structural requirements for the assembly of Norwalk virus-like particles. J Virol. 2002 Apr; 76(8):4044-55. PMID: 11907243.
      View in: PubMed
    88. Crawford SE, Mukherjee SK, Estes MK, Lawton JA, Shaw AL, Ramig RF, Prasad BV. Trypsin cleavage stabilizes the rotavirus VP4 spike. J Virol. 2001 Jul; 75(13):6052-61. PMID: 11390607.
      View in: PubMed
    89. Nason EL, Wetzel JD, Mukherjee SK, Barton ES, Prasad BV, Dermody TS. A monoclonal antibody specific for reovirus outer-capsid protein sigma3 inhibits sigma1-mediated hemagglutination by steric hindrance. J Virol. 2001 Jul; 75(14):6625-34. PMID: 11413330.
      View in: PubMed
    90. Mathieu M, Petitpas I, Navaza J, Lepault J, Kohli E, Pothier P, Prasad BV, Cohen J, Rey FA. Atomic structure of the major capsid protein of rotavirus: implications for the architecture of the virion. EMBO J. 2001 Apr 02; 20(7):1485-97. PMID: 11285213.
      View in: PubMed
    91. Pesavento JB, Lawton JA, Estes ME, Venkataram Prasad BV. The reversible condensation and expansion of the rotavirus genome. Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):1381-6. PMID: 11171959.
      View in: PubMed
    92. Lawton JA, Estes MK, Prasad BV. Identification and characterization of a transcription pause site in rotavirus. J Virol. 2001 Feb; 75(4):1632-42. PMID: 11160661.
      View in: PubMed
    93. Prasad BV, Crawford S, Lawton JA, Pesavento J, Hardy M, Estes MK. Structural studies on gastroenteritis viruses. Novartis Found Symp. 2001; 238:26-37; discussion 37-46. PMID: 11444031.
      View in: PubMed
    94. Prasad BV, Crawford SE, Lawton JA, Pesavento J, Hardy M, Estes MK. Structural studies on gastroenteritis viruses. Novartis Found Symp. 2001; 238:26-37.
    95. Nason EL, Samal SK, Venkataram Prasad BV. Trypsin-induced structural transformation in aquareovirus. J Virol. 2000 Jul; 74(14):6546-55. PMID: 10864668.
      View in: PubMed
    96. Venkataram Prasad BV, Hardy ME, Estes MK. Structural studies of recombinant Norwalk capsids. J Infect Dis. 2000 May; 181 Suppl 2:S317-21. PMID: 10804144.
      View in: PubMed
    97. Venkataram Prasad BV, Estes MK. Electron cryomicroscopy and computer image processing techniques : use in structure-function studies of rotavirus. Methods Mol Med. 2000; 34:9-31. PMID: 21318853.
      View in: PubMed
    98. Lawton JA, Estes MK, Prasad BV. Mechanism of genome transcription in segmented dsRNA viruses. Adv Virus Res. 2000; 55:185-229. PMID: 11050943.
      View in: PubMed
    99. Prasad BV, Hardy ME, Dokland T, Bella J, Rossmann MG, Estes MK. X-ray crystallographic structure of the Norwalk virus capsid. Science. 1999 Oct 08; 286(5438):287-90. PMID: 10514371.
      View in: PubMed
    100. Hill CL, Booth TF, Prasad BV, Grimes JM, Mertens PP, Sutton GC, Stuart DI. The structure of a cypovirus and the functional organization of dsRNA viruses. Nat Struct Biol. 1999 Jun; 6(6):565-8. PMID: 10360362.
      View in: PubMed
    101. Lawton JA, Estes MK, Prasad BV. Comparative structural analysis of transcriptionally competent and incompetent rotavirus-antibody complexes. Proc Natl Acad Sci U S A. 1999 May 11; 96(10):5428-33. PMID: 10318900.
      View in: PubMed
    102. Paredes AM, Heidner H, Thuman-Commike P, Prasad BV, Johnston RE, Chiu W. Structural localization of the E3 glycoprotein in attenuated Sindbis virus mutants. J Virol. 1998 Feb; 72(2):1534-41. PMID: 9445057.
      View in: PubMed
    103. Lawton JA, Zeng CQ, Mukherjee SK, Cohen J, Estes MK, Prasad BV. Three-dimensional structural analysis of recombinant rotavirus-like particles with intact and amino-terminal-deleted VP2: implications for the architecture of the VP2 capsid layer. J Virol. 1997 Oct; 71(10):7353-60. PMID: 9311813.
      View in: PubMed
    104. Grimes JM, Jakana J, Ghosh M, Basak AK, Roy P, Chiu W, Stuart DI, Prasad BV. An atomic model of the outer layer of the bluetongue virus core derived from X-ray crystallography and electron cryomicroscopy. Structure. 1997 Jul 15; 5(7):885-93. PMID: 9261080.
      View in: PubMed
    105. Weiss RS, Lee SS, Prasad BV, Javier RT. Human adenovirus early region 4 open reading frame 1 genes encode growth-transforming proteins that may be distantly related to dUTP pyrophosphatase enzymes. J Virol. 1997 Mar; 71(3):1857-70. PMID: 9032316.
      View in: PubMed
    106. Lawton JA, Estes MK, Prasad BV. Three-dimensional visualization of mRNA release from actively transcribing rotavirus particles. Nat Struct Biol. 1997 Feb; 4(2):118-21. PMID: 9033591.
      View in: PubMed
    107. Prasad BV, Estes MK. . Molecular basis of rotavirus replication: Structure-function correlations. In Structural Biology of Viruses, (Editors, Chiu, W., Burnett, R. and Garcia, R.). Oxford University Press. 1997; 239-269.
    108. Shaw AL, Samal SK, Subramanian K, Prasad BV. The structure of aquareovirus shows how the different geometries of the two layers of the capsid are reconciled to provide symmetrical interactions and stabilization. Structure. 1996 Aug 15; 4(8):957-67. PMID: 8805574.
      View in: PubMed
    109. Prasad BV, Rothnagel R, Zeng CQ, Jakana J, Lawton JA, Chiu W, Estes MK. Visualization of ordered genomic RNA and localization of transcriptional complexes in rotavirus. Nature. 1996 Aug 01; 382(6590):471-3. PMID: 8684490.
      View in: PubMed
    110. Thuman-Commike PA, Greene B, Jakana J, Prasad BV, King J, Prevelige PE, Chiu W. Three-dimensional structure of scaffolding-containing phage p22 procapsids by electron cryo-microscopy. J Mol Biol. 1996 Jul 05; 260(1):85-98. PMID: 8676394.
      View in: PubMed
    111. Shaw AL, Rothnagel R, Zeng CQ, Lawton JA, Ramig RF, Estes MK, Prasad BV. Rotavirus structure: interactions between the structural proteins. Arch Virol Suppl. 1996; 12:21-7. PMID: 9015098.
      View in: PubMed
    112. Prasad BV, Hardy ME, Jiang X, Estes MK. Structure of Norwalk virus. Arch Virol Suppl. 1996; 12:237-42. PMID: 9015120.
      View in: PubMed
    113. Lawton JA, Venkataram Prasad BV. Automated software package for icosahedral virus reconstruction. J Struct Biol. 1996 Jan-Feb; 116(1):209-15. PMID: 8742745.
      View in: PubMed
    114. Singh S, Rothnagel R, Prasad BV, Buckley B. Expression of tobacco ringspot virus capsid protein and satellite RNA in insect cells and three-dimensional structure of tobacco ringspot virus-like particles. Virology. 1995 Nov 10; 213(2):472-81. PMID: 7491772.
      View in: PubMed
    115. Zhou ZH, Prasad BV, Jakana J, Rixon FJ, Chiu W. Protein subunit structures in the herpes simplex virus A-capsid determined from 400 kV spot-scan electron cryomicroscopy. J Mol Biol. 1994 Sep 30; 242(4):456-69. PMID: 7932703.
      View in: PubMed
    116. Prasad BV, Rothnagel R, Jiang X, Estes MK. Three-dimensional structure of baculovirus-expressed Norwalk virus capsids. J Virol. 1994 Aug; 68(8):5117-25. PMID: 8035511.
      View in: PubMed
    117. Prasad BV, Matson DO, Smith AW. Three-dimensional structure of calicivirus. J Mol Biol. 1994 Jul 15; 240(3):256-64. PMID: 8028008.
      View in: PubMed
    118. Zeng CQ, Labbé M, Cohen J, Prasad BV, Chen D, Ramig RF, Estes MK. Characterization of rotavirus VP2 particles. Virology. 1994 May 15; 201(1):55-65. PMID: 8178489.
      View in: PubMed
    119. Schmid MF, Prasad BV, Chiu W. Structural studies of viruses by electron cryomicroscopy. Arch Virol Suppl. 1994; 9:523-9. PMID: 8032281.
      View in: PubMed
    120. Prasad BV, Chiu W. Structure of rotavirus. Curr Top Microbiol Immunol. 1994; 185:9-29. PMID: 8050286.
      View in: PubMed
    121. Paredes AM, Brown DT, Rothnagel R, Chiu W, Schoepp RJ, Johnston RE, Prasad BV. Three-dimensional structure of a membrane-containing virus. Proc Natl Acad Sci U S A. 1993 Oct 01; 90(19):9095-9. PMID: 8415660.
      View in: PubMed
    122. Shaw AL, Rothnagel R, Chen D, Ramig RF, Chiu W, Prasad BV. Three-dimensional visualization of the rotavirus hemagglutinin structure. Cell. 1993 Aug 27; 74(4):693-701. PMID: 8395350.
      View in: PubMed
    123. Prasad BV, Prevelige PE, Marietta E, Chen RO, Thomas D, King J, Chiu W. Three-dimensional transformation of capsids associated with genome packaging in a bacterial virus. J Mol Biol. 1993 May 05; 231(1):65-74. PMID: 8496966.
      View in: PubMed
    124. Chiu W, Schmid MF, Prasad BV. Teaching electron diffraction and imaging of macromolecules. Biophys J. 1993 May; 64(5):1610-25. PMID: 8324196.
      View in: PubMed
    125. Guevara J, Spurlino J, Jan AY, Yang CY, Tulinsky A, Prasad BV, Gaubatz JW, Morrisett JD. Proposed mechanisms for binding of apo[a] kringle type 9 to apo B-100 in human lipoprotein[a]. Biophys J. 1993 Mar; 64(3):686-700. PMID: 8386013.
      View in: PubMed
    126. Guevara J, Knapp RD, Spurlino J, Prasad BV, Morrisett JD. Method for calculating 3-D coordinates from molecular stereograms. J Protein Chem. 1992 Dec; 11(6):653-6. PMID: 1281634.
      View in: PubMed
    127. Citovsky V, Wong ML, Shaw AL, Prasad BV, Zambryski P. Visualization and characterization of tobacco mosaic virus movement protein binding to single-stranded nucleic acids. Plant Cell. 1992 Apr; 4(4):397-411. PMID: 1379865.
      View in: PubMed
    128. Prasad BV, Yamaguchi S, Roy P. Three-dimensional structure of single-shelled bluetongue virus. J Virol. 1992 Apr; 66(4):2135-42. PMID: 1312624.
      View in: PubMed
    129. Prasad BV, Degn LL, Jeng TW, Chiu W. Estimation of allowable errors for tilt parameter determination in protein electron crystallography. Ultramicroscopy. 1990 Oct; 33(4):281-5. PMID: 2260229.
      View in: PubMed
    130. Prasad BV, Burns JW, Marietta E, Estes MK, Chiu W. Localization of VP4 neutralization sites in rotavirus by three-dimensional cryo-electron microscopy. Nature. 1990 Feb 01; 343(6257):476-9. PMID: 2153941.
      View in: PubMed
    131. Schrag JD, Prasad BV, Rixon FJ, Chiu W. Three-dimensional structure of the HSV1 nucleocapsid. Cell. 1989 Feb 24; 56(4):651-60. PMID: 2537151.
      View in: PubMed
    132. Prasad BV, Wang GJ, Clerx JP, Chiu W. Three-dimensional structure of rotavirus. J Mol Biol. 1988 Jan 20; 199(2):269-75. PMID: 2832610.
      View in: PubMed
    133. Talmon Y, Prasad BV, Clerx JP, Wang GJ, Chiu W, Hewlett MJ. Electron microscopy of vitrified-hydrated La Crosse virus. J Virol. 1987 Jul; 61(7):2319-21. PMID: 3586135.
      View in: PubMed
    134. Prasad BV, Chiu W. Sequence comparison of single-stranded DNA binding proteins and its structural implications. J Mol Biol. 1987 Feb 05; 193(3):579-84. PMID: 3295261.
      View in: PubMed
    135. Prasad BV, Wang GJ, Clerx JPM, and Chiu W. Cryo electron microscopy of spherical viruses: An application to rotaviruses. Micron and Microscopica Acta. 1987; 18(4):327-331.
    136. Chiu W, Jeng TW, Degn LL, Prasad BV. Potential for high-resolution electron crystallography at intermediate high voltage. Ann N Y Acad Sci. 1986; 483:149-56. PMID: 3471122.
      View in: PubMed
    137. Prasad BV, Balaram P. The stereochemistry of peptides containing alpha-aminoisobutyric acid. CRC Crit Rev Biochem. 1984; 16(4):307-48. PMID: 6389004.
      View in: PubMed
    138. Prasad BV, Balaram H, Balaram p. Acyclic peptides as conformational models. Crystal structure of Boc-Aib-Leu-Pro-NHMe ±2H2O. Int J Pept Protein Res. 1984; 24(2):135-140.
    139. Prasad BV. Sci. Acad. Medals for Young Scientists - Lectures, Indian National Science Academy. Molecular model systems for peptide folding. 1983; 156-182.
    140. Ravi A, Prasad BV, Balaram P. . Cyclic peptide disulphides. Solution and solid state conformation of Boc-Cys-Pro-Aib-Cys-NHMe, A disulphide bridged helix. J. Am. Chem. Soc. 1983; 105:105-109.
    141. Prasad BV, Sudha TS, Balaram P. Molecular structure of Boc-Aib-Aib-Phe-Met-NH 2· DMSO. A fragment of a biologically active enkephalin analogue. J. Chem. Soc. Perkin Trans 1. 1983; 417-421.
    142. Balaram H, Prasad BV, Balaram P. Multiple conformational states of a Pro-Pro peptide. Solid-state and solution conformations of Boc-Aib-Pro-Pro-NHMe. J. Amer. Chem. Soc. 1983; 105(12):4065-4071.
    143. Balaram H, Enkatara Prasad BV, Balaram P. Conformational transitions in a Pro-Pro peptide on dissolution of single crystals. Biochem Biophys Res Commun. 1982 Dec 15; 109(3):825-31. PMID: 7159445.
      View in: PubMed
    144. Venkatachalapathi YV, Prasad BV, Balaram P. Conformational analysis of small disulfide loops. Spectroscopic and theoretical studies on a synthetic cyclic tetrapeptide containing cystine. Biochemistry. 1982 Oct 26; 21(22):5502-9. PMID: 7171571.
      View in: PubMed
    145. Prasad BV, Balaram H, Balaram, P. Type II ß-turn conformation of pivaloyl-L-prolyl-a-aminoisobutyryl-N-methylamide: Theoretical, spectroscopic, and X-ray studies. Biopolymers. 1982; 21(7):1261–1273.
    146. Prasad BV, Balaram P. X-Pro peptides. A theoretical study of the hydrogen bonded conformations of (a-aminoisobutyryl-L-prolyl) n sequences. Int J Pept Protein Res. 1982; 4(2):99-102.
    147. Suguna K, Ramakumar S, Shamala N, Prasad BV, Balaram P. Crystal structures of diketopiperazines containing a-aminoisobutyric acid: Cyclo (Aib-Aib) and cyclo (Aib-L-Ile). Biopolymers. 1982; 21(9):1847-1855.
    148. Prasad BV, Balaram P . Stereochemically constrained peptides. Model systems for the study of peptide conformations. in "Conformation in Biology" (R. Srinivasan, R.H. Sarma, eds). 1982; 133-140.
    149. Prasad BV, Ravi A, Balaram P. Molecular structure of a cyclic tetrapeptide disulfide. A novel 3(10) helical conformation with an S-S bridge. Biochem Biophys Res Commun. 1981 Dec 31; 103(4):1138-44. PMID: 7332588.
      View in: PubMed
    150. Prasad BV, Shamala N, Nagaraj R, Balaram P. The crystal structure of benzyloxycarbonyl-(-aminoisobutyryl) 2-L-alanyl methyl ester. Acta Crystallogr Section B: Structural Crystallography and Crystal Chemistry. 1980; 36(1):107-110.
    151. Prasad BV, Sasisekharan V. Conformation of Poly-(a-Aminoisobutyric Acid): A Modified a-Helix. Curr. Sci. 1979; 48(12):517-519.
    152. Prasad BV, Shamala N, Nagaraj R, Chandrasekaran R, Balaram P. Crystal and molecular structure of benzyloxycarbonyl-a-aminoisobutyryl-L-prolyl methylamide: The observation of an X2-Pro3 Type III ß-Turn. Biopolymers. 1979; 18(7):1635-1646.
    153. Prasad BV, Sasisekharan V. A Case Study of the Conformation of Poly (a-aminoisobutyric acid): a-or 310-Helix. Macromolecules. 1979; 12(6):1107-1110.
    154. Chandrasekaran R, Venkataram Prasad BV. The conformation of polypeptides containing alternating L- and D-amino acids. CRC Crit Rev Biochem. 1978; 5(2):125-61. PMID: 363349.
      View in: PubMed
    155. Prasad BV, Chandrasekaran R. Conformation of polypeptide chains containing both L- and D-residues. II. Double-helical structures of poly-LD-peptides. Int J Pept Protein Res. 1977; 10(2):129-38. PMID: 892986.
      View in: PubMed
    Prasad's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description