AMOS GAIKWAD

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yost CM, Gaikwad AS, Parsons DW, Rabin KR, Gant VU, Fisher KE, Marcogliese AN, Schafer ES. Aberrant leukemia-associated immunophenotype as potential harbinger of lineage switch in KMT2A-rearranged leukemia: a case series. Leuk Lymphoma. 2020 Sep 02; 1-4. PMID: 32876512.
      Citations:    Fields:    
    2. Stevens AM, Xiang M, Heppler LN, Tošic I, Jiang K, Munoz JO, Gaikwad AS, Horton TM, Long X, Narayanan P, Seashore EL, Terrell MC, Rashid R, Krueger MJ, Mangubat-Medina AE, Ball ZT, Sumazin P, Walker SR, Hamada Y, Oyadomari S, Redell MS, Frank DA. Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation. Blood Adv. 2019 12 23; 3(24):4215-4227. PMID: 31856268.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Hashmi SK, Punia JN, Marcogliese AN, Gaikwad AS, Fisher KE, Roy A, Rao P, Lopez-Terrada DH, Ringrose J, Loh ML, Niemeyer CM, Rau RE. Sustained remission with azacitidine monotherapy and an aberrant precursor B-lymphoblast population in juvenile myelomonocytic leukemia. Pediatr Blood Cancer. 2019 10; 66(10):e27905. PMID: 31250550.
      Citations:    Fields:    Translation:HumansCells
    4. Coffey AM, Lewis A, Marcogliese AN, Elghetany MT, Punia JN, Chang CC, Allen CE, McClain KL, Gaikwad AS, El-Mallawany NK, Curry CV. A clinicopathologic study of the spectrum of systemic forms of EBV-associated T-cell lymphoproliferative disorders of childhood: A single tertiary care pediatric institution experience in North America. Pediatr Blood Cancer. 2019 08; 66(8):e27798. PMID: 31099136.
      Citations: 1     Fields:    Translation:HumansCellsCTClinical Trials
    5. Namazzi R, Gaikwad A, Wasswa P, Cubbage M, Kambugu JB, Kasirye P, Geriga F, Allen C, Lubega J. Improving diagnosis and treatment of acute childhood leukemia in Uganda: impact of flow cytometry. Blood Adv. 2018 11 30; 2(Suppl 1):21-23. PMID: 30504192.
      Citations: 1     Fields:    Translation:Humans
    6. Long DJ, Gaikwad A, Multani A, Pathak S, Montgomery CA, Gonzalez FJ, Jaiswal AK. Retraction: Disruption of the NAD(P)H:Quinone Oxidoreductase 1 (NQO1) Gene in Mice Causes Myelogenous Hyperplasia. Cancer Res. 2018 Nov 15; 78(22):6526. PMID: 30442815.
      Citations:    Fields:    
    7. Arasaratnam RJ, Tzannou I, Gray T, Aguayo-Hiraldo PI, Kuvalekar M, Naik S, Gaikwad A, Liu H, Miloh T, Vera JF, Himes RW, Munoz FM, Leen AM. Dynamics of virus-specific T cell immunity in pediatric liver transplant recipients. Am J Transplant. 2018 09; 18(9):2238-2249. PMID: 29900673.
      Citations:    Fields:    Translation:HumansCellsCTClinical Trials
    8. Whittle SB, Punia JN, López-Terrada D, Gaikwad A, Hampton OA, Heczey A. Therapy-related Acute Leukemia With Mixed Phenotype and Novel t(1: 6)(q25;p23) After Treatment for High-risk Neuroblastoma. J Pediatr Hematol Oncol. 2017 11; 39(8):e486-e488. PMID: 28902076.
      Citations:    Fields:    Translation:HumansCells
    9. Stevens AM, Miller JM, Munoz JO, Gaikwad AS, Redell MS. Interleukin-6 levels predict event-free survival in pediatric AML and suggest a mechanism of chemotherapy resistance. Blood Adv. 2017 Aug 08; 1(18):1387-1397. PMID: 29296780.
      Citations: 6     Fields:    
    10. Bonifant CL, Szoor A, Torres D, Joseph N, Velasquez MP, Iwahori K, Gaikwad A, Nguyen P, Arber C, Song XT, Redell M, Gottschalk S. CD123-Engager T Cells as a Novel Immunotherapeutic for Acute Myeloid Leukemia. Mol Ther. 2016 09 29; 24(9):1615-26. PMID: 27401038.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    11. Gaikwad A, Bonifant CL, Cubbage M, Goltsova T, Mudannayake M, Ringrose J, Punia J, Lopez-Terrada D, Sheehan AM. Detection of lymphoid and myeloid lineages in infantile B-cell acute lymphoblastic leukemia with mixed-lineage leukemia rearrangement by use of flow cytometry and cytogenetic analysis. Clin Lymphoma Myeloma Leuk. 2014 Sep; 14 Suppl:S2-5. PMID: 25486951.
      Citations:    Fields:    Translation:HumansCells
    12. Gaikwad AS, Donohue RE, Elghetany MT, Sheehan AM, Lu XY, Gramatges MM, McClain KL, Mistretta TA, Punia JN, Moore TJ, Goltsova T, Cubbage M, Curry CV. Expression of CD25 is a specific and relatively sensitive marker for the Philadelphia chromosome (BCR-ABL1) translocation in pediatric B acute lymphoblastic leukemia. Int J Clin Exp Pathol. 2014; 7(9):6225-30. PMID: 25337274.
      Citations: 4     Fields:    Translation:HumansCells
    13. Quintás-Cardama A, Manshouri T, Estrov Z, Harris D, Zhang Y, Gaikwad A, Kantarjian HM, Verstovsek S. Preclinical characterization of atiprimod, a novel JAK2 AND JAK3 inhibitor. Invest New Drugs. 2011 Oct; 29(5):818-26. PMID: 20372971.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    14. Allen CE, Li L, Peters TL, Leung HC, Yu A, Man TK, Gurusiddappa S, Phillips MT, Hicks MJ, Gaikwad A, Merad M, McClain KL. Cell-specific gene expression in Langerhans cell histiocytosis lesions reveals a distinct profile compared with epidermal Langerhans cells. J Immunol. 2010 Apr 15; 184(8):4557-67. PMID: 20220088.
      Citations: 75     Fields:    Translation:HumansCells
    15. Gaikwad A, Rye CL, Devidas M, Heerema NA, Carroll AJ, Izraeli S, Plon SE, Basso G, Pession A, Rabin KR. Prevalence and clinical correlates of JAK2 mutations in Down syndrome acute lymphoblastic leukaemia. Br J Haematol. 2009 Mar; 144(6):930-2. PMID: 19120350.
      Citations: 34     Fields:    Translation:HumansCells
    16. Manshouri T, Quintás-Cardama A, Nussenzveig RH, Gaikwad A, Estrov Z, Prchal J, Cortes JE, Kantarjian HM, Verstovsek S. The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation. Cancer Sci. 2008 Jun; 99(6):1265-73. PMID: 18482053.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    17. Zhang C, Li B, Gaikwad AS, Haridas V, Xu Z, Gutterman JU, Duvic M. Avicin D selectively induces apoptosis and downregulates p-STAT-3, bcl-2, and survivin in cutaneous T-cell lymphoma cells. J Invest Dermatol. 2008 Nov; 128(11):2728-2735. PMID: 18496567.
      Citations: 13     Fields:    Translation:HumansCells
    18. Agarwal N, Kutlar F, Mojica-Henshaw MP, Ou CN, Gaikwad A, Reading NS, Bailey L, Kutlar A, Prchal JT. Missense mutation of the last nucleotide of exon 1 (G->C) of beta globin gene not only leads to undetectable mutant peptide and transcript but also interferes with the expression of wild allele. Haematologica. 2007 Dec; 92(12):1715-6. PMID: 18056002.
      Citations: 2     Fields:    Translation:HumansCells
    19. Gaikwad A, Prchal JT. Study of two tyrosine kinase inhibitors on growth and signal transduction in polycythemia vera. Exp Hematol. 2007 Nov; 35(11):1647-56. PMID: 17976517.
      Citations: 2     Fields:    Translation:HumansCells
    20. Xu ZX, Liang J, Haridas V, Gaikwad A, Connolly FP, Mills GB, Gutterman JU. A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase. Cell Death Differ. 2007 Nov; 14(11):1948-57. PMID: 17690712.
      Citations: 31     Fields:    Translation:HumansCells
    21. Gaikwad A, Verstovsek S, Yoon D, Chang KT, Manshouri T, Nussenzveig R, Cortes J, Vainchenker W, Prchal JT. Imatinib effect on growth and signal transduction in polycythemia vera. Exp Hematol. 2007 Jun; 35(6):931-8. PMID: 17533047.
      Citations: 11     Fields:    Translation:HumansCells
    22. Gaikwad A, Nussenzveig R, Liu E, Gottshalk S, Chang K, Prchal JT. In vitro expansion of erythroid progenitors from polycythemia vera patients leads to decrease in JAK2 V617F allele. Exp Hematol. 2007 Apr; 35(4):587-95. PMID: 17379069.
      Citations: 18     Fields:    Translation:HumansCells
    23. Nussenzveig RH, Swierczek SI, Jelinek J, Gaikwad A, Liu E, Verstovsek S, Prchal JF, Prchal JT. Polycythemia vera is not initiated by JAK2V617F mutation. Exp Hematol. 2007 Jan; 35(1):32-8. PMID: 17198871.
      Citations: 81     Fields:    Translation:HumansCells
    24. Nussenzveig RH, Lingam HB, Gaikwad A, Zhu Q, Jing N, Prchal JT. A novel mutation of the cytochrome-b5 reductase gene in an Indian patient: the molecular basis of type I methemoglobinemia. Haematologica. 2006 Nov; 91(11):1542-5. PMID: 17082011.
      Citations: 2     Fields:    Translation:Humans
    25. Gutterman JU, Lai HT, Yang P, Haridas V, Gaikwad A, Marcus S. Effects of the tumor inhibitory triterpenoid avicin G on cell integrity, cytokinesis, and protein ubiquitination in fission yeast. Proc Natl Acad Sci U S A. 2005 Sep 06; 102(36):12771-6. PMID: 16118282.
      Citations: 6     Fields:    Translation:AnimalsCells
    26. Iskander K, Gaikwad A, Paquet M, Long DJ, Brayton C, Barrios R, Jaiswal AK. Lower induction of p53 and decreased apoptosis in NQO1-null mice lead to increased sensitivity to chemical-induced skin carcinogenesis. Cancer Res. 2005 Mar 15; 65(6):2054-8. PMID: 15781611.
      Citations: 29     Fields:    Translation:AnimalsCells
    27. Gaikwad A, Poblenz A, Haridas V, Zhang C, Duvic M, Gutterman J. Triterpenoid electrophiles (avicins) suppress heat shock protein-70 and x-linked inhibitor of apoptosis proteins in malignant cells by activation of ubiquitin machinery: implications for proapoptotic activity. Clin Cancer Res. 2005 Mar 01; 11(5):1953-62. PMID: 15756021.
      Citations: 12     Fields:    Translation:HumansCells
    28. Stringer JL, Gaikwad A, Gonzales BN, Long DJ, Marks LM, Jaiswal AK. Presence and induction of the enzyme NAD(P)H: quinone oxidoreductase 1 in the central nervous system. J Comp Neurol. 2004 Apr 05; 471(3):289-97. PMID: 14991562.
      Citations: 8     Fields:    Translation:Animals
    29. Haridas V, Hanausek M, Nishimura G, Soehnge H, Gaikwad A, Narog M, Spears E, Zoltaszek R, Walaszek Z, Gutterman JU. Triterpenoid electrophiles (avicins) activate the innate stress response by redox regulation of a gene battery. J Clin Invest. 2004 Jan; 113(1):65-73. PMID: 14702110.
      Citations: 22     Fields:    Translation:HumansCells
    30. Long DJ, Iskander K, Gaikwad A, Arin M, Roop DR, Knox R, Barrios R, Jaiswal AK. Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity. J Biol Chem. 2002 Nov 29; 277(48):46131-9. PMID: 12351651.
      Citations: 23     Fields:    Translation:AnimalsCells
    31. Gaikwad A, Hop DV, Mukherjee SK. A 70-kDa chloroplast DNA polymerase from pea ( Pisum sativum) that shows high processivity and displays moderate fidelity. Mol Genet Genomics. 2002 Mar; 267(1):45-56. PMID: 11919714.
      Citations: 3     Fields:    Translation:AnimalsCells
    32. Gaikwad A, Long DJ, Stringer JL, Jaiswal AK. In vivo role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in the regulation of intracellular redox state and accumulation of abdominal adipose tissue. J Biol Chem. 2001 Jun 22; 276(25):22559-64. PMID: 11309386.
      Citations: 52     Fields:    Translation:AnimalsCells
    33. Gaikwad A, Van Hop D, Mukherjee SK. Carboxy terminal region of a chloroplast DNA polymerase accessory factor stimulates DNA polymerase activity. Indian J Biochem Biophys. 2000 Dec; 37(6):424-32. PMID: 11355629.
      Citations: 1     Fields:    Translation:Cells
    34. Gaikwad A, Babbarwal V, Pant V, Mukherjee SK. Pea chloroplast FtsZ can form multimers and correct the thermosensitive defect of an Escherichia coli ftsZ mutant. Mol Gen Genet. 2000 Mar; 263(2):213-21. PMID: 10778739.
      Citations: 11     Fields:    Translation:AnimalsCells
    35. Ehtesham NZ, Phan TN, Gaikwad A, Sopory SK, Tuteja N. Calnexin from Pisum sativum: cloning of the cDNA and characterization of the encoded protein. DNA Cell Biol. 1999 Nov; 18(11):853-62. PMID: 10595399.
      Citations: 6     Fields:    Translation:AnimalsCells
    36. Gaikwad A, Tewari KK, Kumar D, Chen W, Mukherjee SK. Isolation and characterisation of the cDNA encoding a glycosylated accessory protein of pea chloroplast DNA polymerase. Nucleic Acids Res. 1999 Aug 01; 27(15):3120-9. PMID: 10454608.
      Citations: 7     Fields:    Translation:AnimalsCells
    37. Gaikwad A, Yadav BS, Reddy MK, Sopory S, Mukherjee SK. Suppression of pea nuclear topoisomerase I enzyme activity by pea PCNA. Plant J. 1999 Jul; 19(2):153-162. PMID: 10476062.
      Citations: 1     Fields:    
    38. Chen W, Gaikwad A, Mukherjee SK, Choudhary NR, Kumar D, Tewari KK. A 43 kDa DNA binding protein from the pea chloroplast interacts with and stimulates the cognate DNA polymerase. Nucleic Acids Res. 1996 Oct 15; 24(20):3953-61. PMID: 8918797.
      Citations: 4     Fields:    Translation:AnimalsCells
    39. Omkumar RV, Gaikwad AS, Ramasarma T. Feedback-type inhibition of activity of 3-hydroxy-3-methylglutaryl coenzyme a reductase by ubiquinone. Biochem Biophys Res Commun. 1992 May 15; 184(3):1280-7. PMID: 1590790.
      Citations: 2     Fields:    Translation:AnimalsCells
    40. Gaikwad AS, Ramasarma T, Ramakrishna Kurup CK. Brown adipose tissue mitochondria are cytochrome c-subsaturated. Mol Cell Biochem. 1991 Jul 10; 105(2):119-25. PMID: 1656204.
      Citations: 2     Fields:    Translation:AnimalsCells
    41. Gaikwad A, Ramasarma T, Kurup CK. Regulation of respiratory activity of brown adipose tissue mitochondria through changes in cytochromes. Biotechnol Appl Biochem. 1990 Oct; 12(5):562-6. PMID: 2288713.
      Citations:    Fields:    Translation:AnimalsCells
    42. Gaikwad AS, Ramasarma T, Kurup CK. Decrease of oxidative activities in brown adipose tissue mitochondria of cold acclimated rats on short term exposure to heat stress. Biochim Biophys Acta. 1990 Jun 26; 1017(3):242-50. PMID: 2372558.
      Citations: 1     Fields:    Translation:AnimalsCells
    43. Gaikwad AS, Ramasarma T, Kurup CK. Changes in thyroid hormone and insulin status of the brown adipose tissue of cold acclimated rats on short term exposure to heat. Indian J Biochem Biophys. 1990 Jun; 27(3):167-71. PMID: 2201623.
      Citations:    Fields:    Translation:Animals
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