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ALLAN CHRIS FERREON

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pharmacology and Chemical Biology
DivisionPharmacology
AddressBaylor College of Medicine
One Baylor Plaza
Houston TX 77030
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    Collapse Research 
    Collapse research activities and funding
    F32NS054468     (FERREON, ALLAN CHRIS)Aug 1, 2006 - Jul 31, 2009
    NIH/NINDS
    Single-Molecule Study of Synuclein Folding/Fibrillation
    Role: Principal Investigator

    R21NS107792     (FERREON, ALLAN CHRIS)Apr 1, 2019 - Mar 31, 2021
    NIH/NINDS
    Mechanism of Pathologic hnRNP Droplet Maturation
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Moosa MM, Ferreon JC, Ferreon ACM. Single-Molecule FRET Detection of Early-Stage Conformations in a-Synuclein Aggregation. Methods Mol Biol. 2019; 1948:221-233. PMID: 30771181.
      View in: PubMed
    2. Choi KJ, Tsoi PS, Moosa MM, Paulucci-Holthauzen A, Liao SJ, Ferreon JC, Ferreon ACM. A Chemical Chaperone Decouples TDP-43 Disordered Domain Phase Separation from Fibrillation. Biochemistry. 2018 Dec 18; 57(50):6822-6826. PMID: 30520303.
      View in: PubMed
    3. Moosa MM, Tsoi PS, Choi KJ, Ferreon ACM, Ferreon JC. Direct Single-Molecule Observation of Sequential DNA Bending Transitions by the Sox2 HMG Box. Int J Mol Sci. 2018 Dec 04; 19(12). PMID: 30518054.
      View in: PubMed
    4. Hu L, Sankaran B, Laucirica DR, Patil K, Salmen W, Ferreon ACM, Tsoi PS, Lasanajak Y, Smith DF, Ramani S, Atmar RL, Estes MK, Ferreon JC, Prasad BVV. Glycan recognition in globally dominant human rotaviruses. Nat Commun. 2018 07 06; 9(1):2631. PMID: 29980685.
      View in: PubMed
    5. Ren Z, Lee J, Moosa MM, Nian Y, Hu L, Xu Z, McCoy JG, Ferreon ACM, Im W, Zhou M. Structure of an EIIC sugar transporter trapped in an inward-facing conformation. Proc Natl Acad Sci U S A. 2018 06 05; 115(23):5962-5967. PMID: 29784777.
      View in: PubMed
    6. Moosa MM, Ferreon JC, Ferreon ACM. Ligand interactions and the protein order-disorder energetic continuum. Semin Cell Dev Biol. 2018 May 12. PMID: 29753880.
      View in: PubMed
    7. Ferreon JC, Jain A, Choi KJ, Tsoi PS, MacKenzie KR, Jung SY, Ferreon AC. Acetylation Disfavors Tau Phase Separation. Int J Mol Sci. 2018 May 04; 19(5). PMID: 29734651.
      View in: PubMed
    8. Moosa MM, Goodman AZ, Ferreon JC, Lee CW, Ferreon ACM, Deniz AA. Denaturant-specific effects on the structural energetics of a protein-denatured ensemble. Eur Biophys J. 2018 Jan; 47(1):89-94. PMID: 29080139.
      View in: PubMed
    9. Jiang X, Chen J, Bajic A, Zhang C, Song X, Carroll SL, Cai ZL, Tang M, Xue M, Cheng N, Schaaf CP, Li F, MacKenzie KR, Ferreon ACM, Xia F, Wang MC, Maletic-Savatic M, Wang J. Corrigendum: Quantitative real-time imaging of glutathione. Nat Commun. 2017 10 03; 8:16163. PMID: 28972204.
      View in: PubMed
    10. Tsoi PS, Choi KJ, Leonard PG, Sizovs A, Moosa MM, MacKenzie KR, Ferreon JC, Ferreon ACM. The N-Terminal Domain of ALS-Linked TDP-43 Assembles without Misfolding. Angew Chem Int Ed Engl. 2017 10 02; 56(41):12590-12593. PMID: 28833982.
      View in: PubMed
    11. Jiang X, Chen J, Bajic A, Zhang C, Song X, Carroll SL, Cai ZL, Tang M, Xue M, Cheng N, Schaaf CP, Li F, MacKenzie KR, Ferreon ACM, Xia F, Wang MC, Maletic-Savatic M, Wang J. Quantitative real-time imaging of glutathione. Nat Commun. 2017 07 13; 8:16087. PMID: 28703127.
      View in: PubMed
    12. Moosa MM, Ferreon AC, Deniz AA. Forced folding of a disordered protein accesses an alternative folding landscape. Chemphyschem. 2015 Jan 12; 16(1):90-4. PMID: 25345588.
      View in: PubMed
    13. Ferreon AC, Ferreon JC, Wright PE, Deniz AA. Modulation of allostery by protein intrinsic disorder. Nature. 2013 Jun 20; 498(7454):390-4. PMID: 23783631.
      View in: PubMed
    14. Ferreon AC, Moosa MM, Gambin Y, Deniz AA. Counteracting chemical chaperone effects on the single-molecule a-synuclein structural landscape. Proc Natl Acad Sci U S A. 2012 Oct 30; 109(44):17826-31. PMID: 22826265.
      View in: PubMed
    15. Ferreon AC, Deniz AA. Osmolyte-, binding-, and temperature-induced transitions of intrinsically disordered proteins. Methods Mol Biol. 2012; 896:257-66. PMID: 22821530.
      View in: PubMed
    16. Ferreon AC, Deniz AA. Protein folding at single-molecule resolution. Biochim Biophys Acta. 2011 Aug; 1814(8):1021-9. PMID: 21303706.
      View in: PubMed
    17. Gambin Y, VanDelinder V, Ferreon AC, Lemke EA, Groisman A, Deniz AA. Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing. Nat Methods. 2011 Mar; 8(3):239-41. PMID: 21297620.
      View in: PubMed
    18. Lee CW, Ferreon JC, Ferreon AC, Arai M, Wright PE. Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation. Proc Natl Acad Sci U S A. 2010 Nov 09; 107(45):19290-5. PMID: 20962272.
      View in: PubMed
    19. Ferreon AC, Moran CR, Ferreon JC, Deniz AA. Alteration of the alpha-synuclein folding landscape by a mutation related to Parkinson's disease. Angew Chem Int Ed Engl. 2010 May 03; 49(20):3469-72. PMID: 20544898.
      View in: PubMed
    20. Ferreon AC, Moran CR, Gambin Y, Deniz AA. Single-molecule fluorescence studies of intrinsically disordered proteins. Methods Enzymol. 2010; 472:179-204. PMID: 20580965.
      View in: PubMed
    21. Vandelinder V, Ferreon AC, Gambin Y, Deniz AA, Groisman A. High-resolution temperature-concentration diagram of alpha-synuclein conformation obtained from a single Förster resonance energy transfer image in a microfluidic device. Anal Chem. 2009 Aug 15; 81(16):6929-35. PMID: 19555081.
      View in: PubMed
    22. Gambin Y, Schug A, Lemke EA, Lavinder JJ, Ferreon AC, Magliery TJ, Onuchic JN, Deniz AA. Direct single-molecule observation of a protein living in two opposed native structures. Proc Natl Acad Sci U S A. 2009 Jun 23; 106(25):10153-8. PMID: 19506258.
      View in: PubMed
    23. Ferreon AC, Gambin Y, Lemke EA, Deniz AA. Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5645-50. PMID: 19293380.
      View in: PubMed
    24. Ferreon AC, Deniz AA. Alpha-synuclein multistate folding thermodynamics: implications for protein misfolding and aggregation. Biochemistry. 2007 Apr 17; 46(15):4499-509. PMID: 17378587.
      View in: PubMed
    25. Ferreon AC, Ferreon JC, Bolen DW, Rösgen J. Protein phase diagrams II: nonideal behavior of biochemical reactions in the presence of osmolytes. Biophys J. 2007 Jan 01; 92(1):245-56. PMID: 17028144.
      View in: PubMed
    26. Auton M, Ferreon AC, Bolen DW. Metrics that differentiate the origins of osmolyte effects on protein stability: a test of the surface tension proposal. J Mol Biol. 2006 Sep 01; 361(5):983-92. PMID: 16889793.
      View in: PubMed
    27. Ferreon JC, Ferreon AC, Li K, Lemon SM. Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease. J Biol Chem. 2005 May 27; 280(21):20483-92. PMID: 15767257.
      View in: PubMed
    28. Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M, Lemon SM. Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):2992-7. PMID: 15710891.
      View in: PubMed
    29. Ferreon AC, Bolen DW. Thermodynamics of denaturant-induced unfolding of a protein that exhibits variable two-state denaturation. Biochemistry. 2004 Oct 26; 43(42):13357-69. PMID: 15491142.
      View in: PubMed
    30. Yang M, Ferreon AC, Bolen DW. Structural thermodynamics of a random coil protein in guanidine hydrochloride. Proteins. 2000; Suppl 4:44-9. PMID: 11013399.
      View in: PubMed
    31. Halos SC, Chu JY, Ferreon AC, Magno MM. Philippine population database at nine microsatellite loci for forensic and paternity applications. Forensic Sci Int. 1999 Apr 12; 101(1):27-32. PMID: 10376334.
      View in: PubMed
    32. Halos SC, Fortuno ES, Ferreon AC, Chu JY, Miranda J, Harada S, Benecke M. Allele frequency distributions of the polymorphic STR loci HUMVWA, HUMFES, HUMF13A01 and the VNTR D1S80 in a Filipino population from Metro Manila. Int J Legal Med. 1998; 111(4):224-6. PMID: 9646171.
      View in: PubMed
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