ALLAN FERREON

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pharmacology and Chemical Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Collapse Research 
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    F32NS054468     (FERREON, ALLAN CHRIS)Aug 1, 2006 - Jul 31, 2009
    NIH/NINDS
    Single-Molecule Study of Synuclein Folding/Fibrillation
    Role: Principal Investigator

    R21NS107792     (FERREON, ALLAN CHRIS)Apr 1, 2019 - Mar 31, 2021
    NIH/NINDS
    Mechanism of Pathologic hnRNP Droplet Maturation
    Role: Principal Investigator

    R21NS109678     (FERREON, ALLAN CHRIS)Aug 15, 2019 - Jul 31, 2021
    NIH/NINDS
    Pharmacologic inhibition of ribonucleoprotein droplet maturation
    Role: Principal Investigator

    R01NS105874     (FERREON, ALLAN CHRIS)Aug 15, 2019 - Jul 31, 2024
    NIH/NINDS
    Phase Transition-Mediated Tau Function and Dysfunction
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tsoi PS, Quan MD, Choi KJ, Dao KM, Ferreon JC, Ferreon ACM. Electrostatic modulation of hnRNPA1 low-complexity domain liquid-liquid phase separation and aggregation. Protein Sci. 2021 07; 30(7):1408-1417. PMID: 33982369.
      Citations: 2     Fields:    
    2. Mitra S, Kumar D, Hu L, Sankaran B, Moosa MM, Rice AP, Ferreon JC, Ferreon ACM, Prasad BVV. Influenza A Virus Protein NS1 Exhibits Strain-Independent Conformational Plasticity. J Virol. 2019 11 01; 93(21). PMID: 31375595.
      Citations: 6     Fields:    Translation:Cells
    3. Moosa MM, Ferreon JC, Ferreon ACM. Single-Molecule FRET Detection of Early-Stage Conformations in a-Synuclein Aggregation. Methods Mol Biol. 2019; 1948:221-233. PMID: 30771181.
      Citations: 1     Fields:    Translation:Cells
    4. Choi KJ, Tsoi PS, Moosa MM, Paulucci-Holthauzen A, Liao SJ, Ferreon JC, Ferreon ACM. A Chemical Chaperone Decouples TDP-43 Disordered Domain Phase Separation from Fibrillation. Biochemistry. 2018 12 18; 57(50):6822-6826. PMID: 30520303.
      Citations: 14     Fields:    Translation:HumansCells
    5. Moosa MM, Tsoi PS, Choi KJ, Ferreon ACM, Ferreon JC. Direct Single-Molecule Observation of Sequential DNA Bending Transitions by the Sox2 HMG Box. Int J Mol Sci. 2018 Dec 04; 19(12). PMID: 30518054.
      Citations: 3     Fields:    Translation:Cells
    6. Hu L, Sankaran B, Laucirica DR, Patil K, Salmen W, Ferreon ACM, Tsoi PS, Lasanajak Y, Smith DF, Ramani S, Atmar RL, Estes MK, Ferreon JC, Prasad BVV. Glycan recognition in globally dominant human rotaviruses. Nat Commun. 2018 07 06; 9(1):2631. PMID: 29980685.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    7. Ferreon JC, Jain A, Choi KJ, Tsoi PS, MacKenzie KR, Jung SY, Ferreon AC. Acetylation Disfavors Tau Phase Separation. Int J Mol Sci. 2018 May 04; 19(5). PMID: 29734651.
      Citations: 35     Fields:    Translation:HumansCells
    8. Moosa MM, Goodman AZ, Ferreon JC, Lee CW, Ferreon ACM, Deniz AA. Denaturant-specific effects on the structural energetics of a protein-denatured ensemble. Eur Biophys J. 2018 Jan; 47(1):89-94. PMID: 29080139.
      Citations: 1     Fields:    Translation:Cells
    9. Jiang X, Chen J, Bajic A, Zhang C, Song X, Carroll SL, Cai ZL, Tang M, Xue M, Cheng N, Schaaf CP, Li F, MacKenzie KR, Ferreon ACM, Xia F, Wang MC, Maletic-Savatic M, Wang J. Corrigendum: Quantitative real-time imaging of glutathione. Nat Commun. 2017 10 03; 8:16163. PMID: 28972204.
      Citations: 1     Fields:    
    10. Tsoi PS, Choi KJ, Leonard PG, Sizovs A, Moosa MM, MacKenzie KR, Ferreon JC, Ferreon ACM. The N-Terminal Domain of ALS-Linked TDP-43 Assembles without Misfolding. Angew Chem Int Ed Engl. 2017 10 02; 56(41):12590-12593. PMID: 28833982.
      Citations: 17     Fields:    Translation:HumansCells
    11. Jiang X, Chen J, Bajic A, Zhang C, Song X, Carroll SL, Cai ZL, Tang M, Xue M, Cheng N, Schaaf CP, Li F, MacKenzie KR, Ferreon ACM, Xia F, Wang MC, Maletic-Savatic M, Wang J. Quantitative real-time imaging of glutathione. Nat Commun. 2017 07 13; 8:16087. PMID: 28703127.
      Citations: 39     Fields:    Translation:HumansCells
    12. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 29753880.
      Citations: 3     Fields:    Translation:HumansCells
    13. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 29784777.
      Citations: 4     Fields:    Translation:Cells
    14. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 31863590.
      Citations: 20     Fields:    Translation:HumansCells
    15. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 34552088.
      Citations:    Fields:    Translation:HumansCells
    16. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 16889793.
      Citations: 18     Fields:    Translation:Cells
    17. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 19555081.
      Citations: 10     Fields:    Translation:HumansCells
    18. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 21297620.
      Citations: 42     Fields:    Translation:HumansCells
    19. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 20962272.
      Citations: 83     Fields:    Translation:Cells
    20. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 20580965.
      Citations: 40     Fields:    Translation:HumansCells
    21. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 25345588.
      Citations: 12     Fields:    Translation:Cells
    22. Ferreon AC, Ferreon JC, Wright PE, Deniz AA. Modulation of allostery by protein intrinsic disorder. Nature. 2013 Jun 20; 498(7454):390-4. PMID: 23783631.
      Citations: 126     Fields:    Translation:HumansAnimalsCells
    23. Ferreon AC, Moosa MM, Gambin Y, Deniz AA. Counteracting chemical chaperone effects on the single-molecule a-synuclein structural landscape. Proc Natl Acad Sci U S A. 2012 Oct 30; 109(44):17826-31. PMID: 22826265.
      Citations: 28     Fields:    Translation:Cells
    24. Ferreon AC, Deniz AA. Osmolyte-, binding-, and temperature-induced transitions of intrinsically disordered proteins. Methods Mol Biol. 2012; 896:257-66. PMID: 22821530.
      Citations: 1     Fields:    Translation:Cells
    25. Ferreon AC, Deniz AA. Protein folding at single-molecule resolution. Biochim Biophys Acta. 2011 Aug; 1814(8):1021-9. PMID: 21303706.
      Citations: 10     Fields:    Translation:Cells
    26. Ferreon AC, Moran CR, Ferreon JC, Deniz AA. Alteration of the alpha-synuclein folding landscape by a mutation related to Parkinson's disease. Angew Chem Int Ed Engl. 2010 May 03; 49(20):3469-72. PMID: 20544898.
      Citations: 32     Fields:    Translation:Cells
    27. Gambin Y, Schug A, Lemke EA, Lavinder JJ, Ferreon AC, Magliery TJ, Onuchic JN, Deniz AA. Direct single-molecule observation of a protein living in two opposed native structures. Proc Natl Acad Sci U S A. 2009 Jun 23; 106(25):10153-8. PMID: 19506258.
      Citations: 30     Fields:    Translation:Cells
    28. Ferreon AC, Gambin Y, Lemke EA, Deniz AA. Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence. Proc Natl Acad Sci U S A. 2009 Apr 07; 106(14):5645-50. PMID: 19293380.
      Citations: 170     Fields:    Translation:Cells
    29. Ferreon AC, Deniz AA. Alpha-synuclein multistate folding thermodynamics: implications for protein misfolding and aggregation. Biochemistry. 2007 Apr 17; 46(15):4499-509. PMID: 17378587.
      Citations: 38     Fields:    Translation:Cells
    30. Ferreon AC, Ferreon JC, Bolen DW, Rösgen J. Protein phase diagrams II: nonideal behavior of biochemical reactions in the presence of osmolytes. Biophys J. 2007 Jan 01; 92(1):245-56. PMID: 17028144.
      Citations: 8     Fields:    Translation:Cells
    31. Ferreon JC, Ferreon AC, Li K, Lemon SM. Molecular determinants of TRIF proteolysis mediated by the hepatitis C virus NS3/4A protease. J Biol Chem. 2005 May 27; 280(21):20483-92. PMID: 15767257.
      Citations: 37     Fields:    Translation:Cells
    32. Li K, Foy E, Ferreon JC, Nakamura M, Ferreon AC, Ikeda M, Ray SC, Gale M, Lemon SM. Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):2992-7. PMID: 15710891.
      Citations: 403     Fields:    Translation:HumansCells
    33. Ferreon AC, Bolen DW. Thermodynamics of denaturant-induced unfolding of a protein that exhibits variable two-state denaturation. Biochemistry. 2004 Oct 26; 43(42):13357-69. PMID: 15491142.
      Citations: 23     Fields:    Translation:Cells
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